CN109172386A

CN109172386A - A kind of compound moisturizing hydrogel

Info

Publication number: CN109172386A
Application number: CN201811183158.1A
Authority: CN
Inventors: 郑延丘
Original assignee: Guangzhou Huaser Technology Co Ltd
Current assignee: Guangzhou Huaser Technology Co Ltd
Priority date: 2018-10-11
Filing date: 2018-10-11
Publication date: 2019-01-11

Abstract

The invention discloses a kind of compound moisturizing hydrogels, it includes the following components'mass percentage: widow's victory 100~500PPM of peptide, purslane extract 1~10%, camomile extract 1~5%, Essential Oil of Acorus tatarinowii 0.2~1%, glycerine polyacrylate 10~30%, propylene glycol 1~5%, glycerine 1~5%, parahydroxyacet-ophenone 0.1~0.5%, pungent glycol 0.1~0.5%, deionized water surplus.Skin sense while with strong moisture-keeping efficacy of the compound moisturizing hydrogel of the present invention also has the function of whitening, crease-resistant and anti-aging, active matter is helped to disperse and permeate, effectively promotion active function clearly without sticky.

Description

A kind of compound moisturizing hydrogel

Technical field

The present invention relates to daily chemical product field more particularly to a kind of compound moisturizing hydrogels.

Background technique

With the improvement of living standards, the irradiation of operating pressure, ultraviolet light, irregular daily life system etc. cause aging to add Speed, to use more extensive of cosmetics, while the requirement to cosmetics is also increasingly particular about, and pursues comfortable salubrious skin sense It also wants both effectiveness simultaneously and realizes beauty, moisturizing moisturizing, the white exquisiteness of skin delays senescence, beautiful life.

Most hydrophilic traditional moisturizing raw materials currently on the market, including polyalcohol, polysaccharide, reed fragrant plant glue oil and macromolecule Hyaluronic acid etc. is all more sticky.On the other hand, moistening effect is influenced by ambient humidity more easily, leads to the effect for retaining hydrone Fruit decline, it is more difficult to reach the purpose of efficient moisture-retention, long-time moistening effect is also undesirable.Furthermore it was developed in cosmetic formulations It is low with effective rate of utilization to be easy to appear effect failure for polypeptide, growth factor, Co-Q10, Polyphenols and other effects property raw material in journey Situation causes product formula cost high effect undesirable.

Summary of the invention

To solve the above problems, the present invention provides a kind of compound moisturizing hydrogel, be it is a kind of have it is not sticky and can The multi-functional glycerine polyacrylate cage type hydrogel of strong moistening effect is provided.Skin can be directly acted on, has one Fixed light diffuses effect, is capable of providing pure and fresh smooth skin sense, and energy cutin-softening layer promotes skin fair and tender such as baby skin.Simultaneously Also have the function of whitening, crease-resistant and anti-aging, active matter is helped to disperse and permeate, effectively promotion active function.

The present invention is achieved through the following technical solutions:

A kind of Multifunctional composite water gel, includes the following components'mass percentage: widow victory 100~500PPM of peptide, horse Sativa extract 1~10%, camomile extract 1~5%, Essential Oil of Acorus tatarinowii 0.2~1%, glycerine polyacrylate 10~ 30%, propylene glycol 1~5%, glycerine 1~5%, parahydroxyacet-ophenone 0.1~0.5%, pungent glycol 0.1~0.5%, deionization Water surplus.

Further, the Multifunctional composite water gel further includes ascorbic acid glucoside 0.1~0.5%.

Further, the Multifunctional composite water gel, further include PCA zinc, Anjidew NL50, PCA magnesium 0.1~ 0.5%, wherein PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

A kind of Multifunctional composite water gel, the purslane extract the preparation method comprises the following steps: (1) washes purslane cauline leaf Decontamination is cleaned, and distilled water slightly soaking flushing 10-15min repetitive operation 2~3 times, dries；(2) it is placed in disinfection cabinet, uses Pasteur's low temperature disinfection sterilizes 30~40min；(3) the purslane cauline leaf after disinfection is placed in juice extractor and is squeezed, obtain purslane Crude extract；(4) purslane crude extract is used into ultrasonic cell disintegration instrument 10~15min of ultrasonic extraction, obtains purslane extract.

A kind of Multifunctional composite water gel, the camomile extract the preparation method comprises the following steps: (1) washes chamomile cauline leaf Decontamination is cleaned, and distilled water slightly soaking flushing 10-15min repetitive operation 2~3 times, dries；(2) it is placed in disinfection cabinet, uses Pasteur's low temperature disinfection sterilizes 30~40min；(3) the chamomile cauline leaf after disinfection is placed in juice extractor and is squeezed, obtain chamomile Crude extract；(4) chamomile crude extract is used into ultrasonic cell disintegration instrument 10~15min of ultrasonic extraction, obtains camomile extract.

A kind of Multifunctional composite water gel, the Essential Oil of Acorus tatarinowii the preparation method comprises the following steps: (1) picks rhizoma acori graminei rhizome Decontamination is cleaned, slightly impregnates, moisturize, and is sliced, dries；(2) be ground into powder with pulverizer, be added 1-4 times of parts by weight 70~ 80% ethyl alcohol immersion 10~extracted after twenty minutes；(3) extraction conditions: 38~45 DEG C of constant temperature extractings, extracting pressure 30~ 37MPa, CO₂2.5~3.2kg/h of flow velocity, 10~23MPa of separating pressure, 1.5~2h of extraction time；(4) separating-purifying obtains stone Calamus volatile oil.

Hydrogel provided by the invention can be used for the preparation of cosmetics, wherein and the additive amount of hydrogel is 0.1~10%, It can be used as preparation of the additive for facial mask.

The invention also discloses a kind of facial masks, further include the component of following mass percent: carbomer 0.1~0.3%, and three Ethanol amine 0.1~0.3%, Chlorphenesin 0.1~0.3%, Phenoxyethanol 0.5~1.0%, deionized water surplus.

Conventional method generally realizes moisture-keeping efficacy using moisturizing, and the present invention uses Hydrogenbond and Van der Waals force shape At lattice structure tightly lockked skin moisture, strong moistening effect is presented.

A kind of Multifunctional composite water gel of the present invention, has the following beneficial effects:

(1) moisture is tightly lockked by the lattice structure that Hydrogenbond and Van der Waals force are formed, there is strong moisturizing effect Fruit is mainly used in medicine and personal care articles field, provides moisture-keeping efficacy for skin and hair, be strong skin-moisturizing, skin Agent；

(2) also have the function of whitening, crease-resistant and anti-aging；

(3) have the function of dispersing and helping active matter infiltration, be the sustained release of other active matters, active matter is in hydrogel shape At moisture film in can there is one uniformly to sprawl, have higher efficiency it, while the infiltration of the intraor extracellular interstitial of cutin It is pressed in the help of hydrogel thoroughly and remains at the state of balance, to allow active matter is continual to seep into skin Thoroughly；

(4) easy to use, it is conveniently used in the opaque products such as various personal care articles formula；

(5) mildly, it does not stimulate, antiallergy；

(6) in the products such as toner, facial mask, lotion, essence, cream and facial cleanser, can play well film forming moisturizing, Skin sense conditioning, the effect for assisting both effectiveness raw material sustained release.

Specific embodiment

In order that those skilled in the art will better understand the technical solution of the present invention, below with reference to embodiment and to this Invention product is described in further detail.Embodiments of the present invention are not limited thereto, and not specifically specified technique is joined Several or condition can refer to routine techniques progress.

Each ingredient involved in composition of the present invention is described as follows:

Rhizoma acori graminei, slightly warm in nature, qi-regulating, promoting blood circulation.For the rhizome of day South section plant rhizoma acori graminei, rhizome and Ye Zhongjun are containing volatilization Oily (0.11~0.42%), main component are beta-Asarones 63.2~81.2%, secondly asarone 8.8~13.7% is stone Bamboo alkene, α-Humuleno, sekishone etc..Also contain amino acid, organic acid and carbohydrate.Beta-Asarone relative molecular mass is small, and liposoluble Property it is preferable, with easy percutaneous absorbtion basic physicochemical property.

The flavones and saponin contained in purslane, which has, removes free radical and antioxidation, can be with delay skin aging.Horse Biologically active amino acid has contraction to vascular smooth muscle in bitterroot, and such contraction has maincenter and tip concurrently Property, it can soothe the skin, pruitus caused by inhibiting because of drying.Purslane extract has anti-drying aging, increasing in winter Add skin comfort degree and remove free radical, improves the comprehensive performance of skin comfort etc..

Embodiment 1

A kind of Multifunctional composite water gel, includes the following components'mass percentage: widow victory peptide 245PPM, purslane mention Take object 5.5%, camomile extract 3%, Essential Oil of Acorus tatarinowii 0.45%, glycerine polyacrylate 20%, propylene glycol 3%, third Triol 3%, parahydroxyacet-ophenone 0.3%, pungent glycol 0.3%, ascorbic acid glucoside 0.3%, PCA zinc, Anjidew NL50, PCA magnesium 0.3%, deionized water surplus.The PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

Embodiment 2

A kind of Multifunctional composite water gel, includes the following components'mass percentage: widow victory peptide 100PPM, purslane mention Take object 1%, camomile extract 1%, Essential Oil of Acorus tatarinowii 0.2%, glycerine polyacrylate 10~30%, propylene glycol 1%, third Triol 1%, parahydroxyacet-ophenone 0.1%, pungent glycol 0.1%, ascorbic acid glucoside 0.1%, PCA zinc, Anjidew NL50, PCA magnesium 0.1%, deionized water surplus.The PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

Embodiment 3

A kind of Multifunctional composite water gel, includes the following components'mass percentage: widow victory peptide 500PPM, purslane mention Take object 10%, camomile extract 5%, Essential Oil of Acorus tatarinowii 1%, glycerine polyacrylate 30%, propylene glycol 5%, glycerine 5%, parahydroxyacet-ophenone 0.5%, pungent glycol 0.5%, ascorbic acid glucoside 0.5%, PCA zinc, Anjidew NL50, PCA magnesium 0.5% are gone Ion water surplus.The PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

Embodiment 4

A kind of Multifunctional composite water gel, includes the following components'mass percentage: widow victory peptide 160PPM, purslane mention Take object 3%, camomile extract 2%, Essential Oil of Acorus tatarinowii 0.35%, glycerine polyacrylate 14%, propylene glycol 2.5%, third Triol 2.5%, parahydroxyacet-ophenone 0.45%, pungent glycol 0.2%, ascorbic acid glucoside 0.2%, PCA zinc, Anjidew NL50, PCA magnesium 0.2%, deionized water surplus.The PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

Embodiment 5

A kind of compound moisturizing hydrogel, includes the following components'mass percentage: widow victory peptide 480PPM, purslane are extracted Object 8.5%, camomile extract 4.5%, Essential Oil of Acorus tatarinowii 0.8%, glycerine polyacrylate 28%, propylene glycol 4.5%, third Triol 4.5%, parahydroxyacet-ophenone 0.2%, pungent glycol 0.45%, ascorbic acid glucoside 0.14%, PCA zinc, Anjidew NL50, PCA magnesium 0.4%, deionized water surplus.The PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

Embodiment 6

A kind of facial mask, includes the following components'mass percentage: hydrogel 0.1% obtained by above-described embodiment 1, card wave Nurse 0.1%, triethanolamine 0.1%, Chlorphenesin 0.1%, Phenoxyethanol 0.5%, deionized water surplus.

Embodiment 7

A kind of facial mask, includes the following components'mass percentage: hydrogel 10% obtained by above-described embodiment 1, card wave Nurse 0.3%, triethanolamine 0.3%, Chlorphenesin 0.3%, Phenoxyethanol 1.0%, deionized water surplus.

Embodiment 8

A kind of facial mask, includes the following components'mass percentage: hydrogel 5%, carbomer obtained by above-described embodiment 1 0.2%, triethanolamine 0.2%, Chlorphenesin 0.2%, Phenoxyethanol 0.8%, deionized water surplus.

Embodiment 9

A kind of facial mask, includes the following components'mass percentage: hydrogel 1%, carbomer obtained by above-described embodiment 1 0.15%, triethanolamine 0.15%, Chlorphenesin 0.15%, Phenoxyethanol 0.85%, deionized water surplus.

Embodiment 10

A kind of facial mask, includes the following components'mass percentage: hydrogel 8.5% obtained by above-described embodiment 1, card wave Nurse 0.25%, triethanolamine 0.25%, Chlorphenesin 0.25%, Phenoxyethanol 0.55%, deionized water surplus.

Comparative example 1

Difference with embodiment 6 is, purslane extract, camomile extract is not added in embodiment 1, and rhizoma acori graminei is waved Hair oil.

Comparative example 2

It is with the difference for implementing 6, few victory peptide 90PPM is added in embodiment 1, purslane extract 11%, chamomile mentions Take object 0.9%, Essential Oil of Acorus tatarinowii 1.1%.

Comparative example 3

Difference with embodiment 6 is, PCA zinc, Anjidew NL50, PCA magnesium is not added in embodiment 1.

Comparative example 4

Difference with embodiment 6 is, few victory peptide is not added in embodiment 1.

Comparative example 5

Difference with embodiment 6 is, few victory 501PPM, purslane extract 0.9%, chamomile are added in embodiment 1 Extract 5.1%, Essential Oil of Acorus tatarinowii 0.15%.

Control group

Certain commercially available moisture saver mask.

Human body patch test

Organize 50 volunteers according to the human skin patch of " cosmetics safety technical specification " (2015 editions) record, The back of subject will be pasted on low sensitization adhesive tape added with the spot tester of tested material or forearm song is surveyed, gently pressed with palm and be allowed to equal It is pasted on skin, continues for 24 hours evenly.Facial mask obtained by 6-10 of the embodiment of the present invention and comparative example 1-5 is tested to human body skin The potential adverse reaction of skin, the results are shown in Table 1.

Table 1

Joined as can be seen from Table 1 facial mask made from the embodiment 6-10 of compound moisturizing hydrogel to human skin without Irritation.

Moisture-keeping efficacy evaluation

Detection effect on probation is carried out to the embodiment 6-10 and comparative example 1-5 product prepared.Rear skin is used by detection Percutaneous water loss amount verifies moisture-keeping efficacy.

Laboratory apparatus:

Moisture of skin scatters and disappears tester: TM300Courage+Khakaza Cologne Germany.

Test environment: 22 DEG C ± 1 DEG C of temperature, humidity is 50% ± 5%

Volunteer requires: effective volunteer at least 80 people；Age is between 18 years old~65 years old；Forearm test zone capacitance method The basic value of moisture of skin analyzer is between 15 years old~45 without serious systemic disease, without immune deficiency or autoimmune disease Person；No active anaphylactia person；Previously to skin-care cosmetics without severe allergy history person；Not using sharp in nearly 1 month Plain class drug and immunosuppressor person；Other clinical test persons are not participated in；Use according to regulations tested material and all information；Before test All volunteers should fill in informed consent form.

Prepare before test: any product (cosmetics or topical drug) cannot be used within 2 days~3 days before recipient site.Test Before, subject, which needs to clean in both hands forearm, to survey, with dry face tissue wiped clean.After cleaning, in subject's both hands forearm Measured zone label is carried out in survey.Before official testing, it should which sit quietly at least 30min in standard compliant room, cannot drink water, preceding Arm exposure, places in test mode, keeps loosening.

Measurement through transepidermal water lost (TEWL)

Measure 80 subjects smear addition embodiment 6-10 and comparative example 1-5 facial mask before and smear 1h, 2h and 4h Moisture of skin windage afterwards calculates TEWL mean value, the results are shown in Table 2.

Table 2: the facial mask water loss amount of different time measurement

TEWL/%	0h	1h	2h	3h	4h
						Embodiment 6	13.9	13.6	12.8	11.2	10.6
Embodiment 7	13.6	13.5	13.1	11.8	11.3
						Embodiment 8	13.9	13.8	13.5	12.9	11.4
Embodiment 9	13.8	13.6	13.4	12.3	10.9
						Embodiment 10	13.8	13.4	12.9	11.9	11.1
Comparative example 1	13.7	13.6	13.6	13.4	13.4
						Comparative example 2	14.1	13.9	13.5	13.1	12.8
Comparative example 3	13.9	13.8	13.4	13.2	12.7
						Comparative example 4	13.8	13.7	13.4	13.3	12.9
Comparative example 5	14.2	13.9	13.6	12.8	12.6
						Blank control	13.8	13.5	13.8	13.4	13.2

As can be seen from Table 2, as time increases, smear embodiment 6-10 facial mask tested region water loss amount by It gradually reduces, therefore adds subject hydrogel in face pack prescription, strong moistening effect can be played, and reduce the water of skin Disperse vector.

Elastic efficacy validation

Detection effect on probation is carried out to the embodiment 6-10 and comparative example 1-5 product prepared.Rear skin is used by detection Elasticity verifies moisture-keeping crease-shedding effect.

Test object: each experimental group is male 20 female 30 (25-50 year old)；Test zone: face；Test equipment: skin Skin elastic apparatus (Cutometer MPA 580).It uses: applying 1 time, persistently use 4 weeks every other day；Test item: skin elasticity.

Method: the environment on the day of subject tests after face cleaning in 23~25 DEG C of room temperature, relative humidity 50%-60% is sat quietly After 30min, looks steadily it and loosen facial muscle groups, gently close eyes.Its face is detected with skin elasticity instrument (Cutometer MPA 580) Portion's skin elasticity, probe is averaged in same tested region duplicate measurements 3 times when measurement.Test environment phase is kept when measurement To temperature, the influence of light, sound interference is avoided, is firmly wanted uniformly using when probe, the pressure of application should be constant.Subject Use the elasticity number for measuring tested region after 1 week, 2 weeks, 3 weeks, 4 weeks again.Terminate measurement, saves data, finishing analysis data.

Test result and evaluation:

The tested region of subject is shown in Table 3 using before and after product, elastic test Value Data analysis is compared:

Tested elasticity of skin variation gradually shows a increasing trend with the product time is used in embodiment 6-10 seen from table 3.By Embodiment 6-10 and comparative example 1-5 comparison can obtain each ingredient in compound moisturizing hydrogel of the invention and act synergistically, and realize brighter Aobvious moistening effect, enhances skin wettability, and compact skin realizes anti-wrinkle effect.

Skin sense verifying

Skin sense detection effect is carried out to hydrogel made from embodiment 1 and tradition, selects 500 volunteers, every test group Each 100 triers.Certain cream is separately added into using hydrogel made from embodiment 1, polyalcohol, polysaccharide, polymer hyaluronic acid In liquid, participant respectively uses 1 time sooner or later daily, persistently uses 1 month.Other any skin cares must not be used to produce in experimentation Product, and subject has been fully completed verification process, and experimental result is shown in Table 4, three states of effect point:

Upper hand skin sense: water profit is salubrious, score value are as follows: 7-10 points；More sticky, score value is 3-7 points；It is sticky, score value 1-3 Point.

Half-dried skin sense: sticky unobvious, score value are as follows: 8-10 points；More sticky, score value is 3-7 points；It is sticky obvious, score value It is 1-3 points.

Table 4:

Absolutely dry skin sense: obvious silty sense, score value are as follows: 8.5-10 points；Silty sense is general, and score value is 3-7 points；Without silty sense, Score value is 0 point.

As shown in Table 4, compound moisturizing hydrogel produced by the present invention can bring salubrious not sticky skin sense.

White-skinned face function verifying

Choose 880 volunteers, every each 80 triers of test group.The face prepared using embodiment 6-10, comparative example 1-5 The commercially available facial mask of film, control group, participant use 1 time daily, persistently use 1 month.Other any shields are not used in experimentation Skin product, and subject has been fully completed verification process, and experimental result is shown in Table 1, and effect divides three grades:

Whitening effect is obvious: whitening effect is obvious, and spot significantly reduces；

Whitening effect is general: whitening effect is general, and spot fading effect is general；

Whitening effect is unobvious: the obscure no improvement of the colour of skin, the colour of skin and difference before are little, skin relaxation, without obvious after Feel.

Table 5: each embodiment, comparative example, control group using effect

It can be seen that compound moisture retention water provided by the embodiment of the present invention from the result of the self-assessment of 5 trier of table Gel has preferable skin white-skinned face function to most trier's skin, also has crease-resistant, compact skin effect, realizes that skin is grown Profit, whitening, water is tender bright, smooth and high resilience.

The present invention is described by way of example above, but the present invention is not limited to above-mentioned specific embodiment, all to be based on Any changes or modifications that the present invention is done are fallen within the scope of the claimed invention.

Claims

1. a kind of compound moisturizing hydrogel, which is characterized in that include the following components'mass percentage: widow's victory peptide 100~ 500PPM, purslane extract 1~10%, camomile extract 1~5%, Essential Oil of Acorus tatarinowii 0.2~1%, glycerol polypropylene Acid esters 10~30%, propylene glycol 1~5%, glycerine 1~5%, parahydroxyacet-ophenone 0.1~0.5%, pungent glycol 0.1~ 0.5%, deionized water surplus.

2. a kind of compound moisturizing hydrogel according to claim 1, which is characterized in that the system of the purslane extract Preparation Method are as follows: (1) purslane cauline leaf is washed away into impurity, cleaned, distilled water slightly soaking flushing 10-15min, repetitive operation 2~3 It is secondary, it dries；(2) it is placed in disinfection cabinet, 30~40min is sterilized using Pasteur's low temperature disinfection；(3) by the purslane stem after disinfection Leaf is placed in juice extractor and squeezes, and obtains purslane crude extract；(4) purslane crude extract is used into ultrasonic cell disintegration instrument ultrasonic extraction 10~15min obtains purslane extract.

3. a kind of compound moisturizing hydrogel according to claim 1, which is characterized in that the system of the camomile extract Preparation Method are as follows: (1) chamomile cauline leaf is washed away into impurity, cleaned, distilled water slightly soaking flushing 10-15min, repetitive operation 2~3 It is secondary, it dries；(2) it is placed in disinfection cabinet, 30~40min is sterilized using Pasteur's low temperature disinfection；(3) by the chamomile stem after disinfection Leaf is placed in juice extractor and squeezes, and obtains chamomile crude extract；(4) chamomile crude extract is used into ultrasonic cell disintegration instrument ultrasonic extraction 10~15min obtains camomile extract.

4. a kind of compound moisturizing hydrogel according to claim 1, which is characterized in that the system of the Essential Oil of Acorus tatarinowii Preparation Method are as follows: (1) rhizoma acori graminei rhizome is picked into impurity, clean, slightly impregnate, moisturize, be sliced, dry；(2) it is ground into pulverizer Powder, 70~80% ethyl alcohol that 1-4 times of parts by weight are added impregnate 10~it is extracted after twenty minutes；(3) extraction conditions: 38~45 DEG C constant temperature extracting, extracting pressure 30~37MPa, CO₂2.5~3.2kg/h of flow velocity, 10~23MPa of separating pressure, extraction time 1.5~2h；(4) separating-purifying obtains Essential Oil of Acorus tatarinowii.

5. a kind of compound moisturizing hydrogel according to claim 1, which is characterized in that the compound moisturizing hydrogel It further include ascorbic acid glucoside 0.1~0.5%.

6. a kind of compound moisturizing hydrogel according to claim 1, which is characterized in that the compound moisturizing hydrogel Further include PCA zinc, Anjidew NL50, PCA magnesium 0.1~0.5%, wherein PCA zinc, Anjidew NL50, PCA magnesium weight ratio be 1:3:2.

7. described in any item compound moisturizing hydrogels according to claim 1~6, which is characterized in that the compound moisturizing Hydrogel can be used for the preparation of cosmetics, wherein additive amount is 0.1~10%.

8. compound moisturizing hydrogel as claimed in claim 7, which is characterized in that the compound moisturizing hydrogel can be used as Additive is used for the preparation of facial mask.

9. a kind of facial mask, which is characterized in that further include the component of following mass percent: carbomer 0.1~0.3%, three ethyl alcohol Amine 0.1~0.3%, Chlorphenesin 0.1~0.3%, Phenoxyethanol 0.5~1.0%, deionized water surplus.