CN108815683B - Device for treating gall-stone and use method and application thereof - Google Patents

Abstract

The application discloses a device for treating gall-stone and a use method and application thereof. The device comprises a placement system and a dissolution treatment system, wherein the placement system comprises a duodenoscope, a guide wire and a catheter A; the duodenoscope is used for extending to the common bile duct sphincter through the mouth cavity, and the guide wire is used for extending into the gall bladder through the duodenoscope; the catheter A is used for sleeving a guide wire and extends into the gall bladder along the guide wire; the outer side of the front end of the conduit A is provided with a controllable opening and closing spherical air bag, and a liquid conveying pipeline and an air bag control pipeline are additionally arranged in the conduit A; the dissolving and removing treatment system comprises a drip chamber which is in a swimming ring shape when in use, wherein an independent inflatable balloon is arranged in the drip chamber, and a cavity outside the inflatable balloon is a medicine storage bin; the inflatable balloon is independently communicated with the reactant bin; the medicine storage bin is provided with a instillation pipe and a liquid injection pipe. The device of the application can uniformly and continuously send the liquid medicine into the gall bladder without affecting the normal life of people, thereby improving the effect of dissolving and removing gall-stone of the liquid medicine.

Description

Device for treating gall-stone and use method and application thereof

Technical Field

The application relates to the field of gall-stone treatment equipment, in particular to a device for treating gall-stone as well as a use method and application thereof.

Background

Gall-stone refers to the disease of gall-stone system, which is classified into gall-stone, gall-stone and choledocholithiasis according to the different positions of the gall-stone in the gall-stone system. According to national survey results, the incidence of gall bladder stones in China is about 52.8%, the incidence of bile duct stones is about 36.2%, and the incidence of common bile duct stones is about 11%.

Current treatment for gall stones mainly includes surgical and non-surgical therapies. Wherein, the operation therapy, such as traditional open-abdomen operation gall bladder lithotomy, open-abdomen exploration gall bladder lithotomy, laparoscopic excision of gall bladder and laparoscopic combined choledochoscope exploration gall bladder lithotomy. Among surgical therapies, cholecystectomy is the most mature and low risk surgery, but nevertheless the overall impact of cholecystectomy on the health of the human system is temporarily not yet defined and concluded reliably, let alone other surgical treatments.

Non-surgical therapies mainly include: the method comprises the steps of extracorporeal shock wave lithotripsy, extracorporeal contact lithotripsy, laser lamp energy contact lithotripsy, lithotripsy extraction of near-scope minimally invasive surgery, lithotripsy of traditional Chinese medicine lithotripsy and lithotripsy promotion and drainage. Wherein, the extracorporeal contact lithotripter is used for lithotripting by placing a choledochoscope into a liquid-electric lithotripter; the Chinese medicine litholytic lithotripsy and promoting the discharge of calculus mainly refers to the oral administration of cholic acid and other medicines for litholytic calculus. Non-surgical therapies, while not affecting the overall human system as do bile dissections or cholecystectomy, currently do not have a relatively effective treatment.

Disclosure of Invention

The application aims to provide a novel device for treating gall-stone, and a use method and application thereof.

The application adopts the following technical scheme:

One aspect of the application discloses a device for treating gall-stone, comprising a placement system and a dissolution treatment system, wherein the placement system comprises a duodenoscope, a guide wire and a catheter A; the duodenoscope is used for extending to the common bile duct sphincter through the mouth, esophagus, stomach, pylorus and duodenum; the guide wire is used for passing through a forceps channel or a biopsy pipeline of the duodenoscope, passing through the common bile duct sphincter and extending into the gall bladder through the common bile duct; the catheter A is used for sleeving a guide wire and extending into the gall bladder along the guide wire; the outer side of the front end of the conduit A is provided with a spherical air bag which can be controlled to open and close, and at least two sets of pipelines are additionally arranged in the pipeline of the conduit A; one set of pipeline is a liquid conveying pipeline, one end of the liquid conveying pipeline extends to or extends out of the front end of the catheter A and is used for releasing the liquid medicine in the gall bladder, and the other end of the liquid conveying pipeline extends out of the external operation end of the catheter A; the other set of pipeline is an air bag control pipeline, one end of the air bag control pipeline is communicated with the spherical air bag, and the other end of the air bag control pipeline extends out of the external operation end of the catheter A; the dissolving and removing treatment system comprises a instillator 1 which is in a swimming ring shape when in use, an independent inflatable balloon 11 is arranged in the instillator 1, and a cavity outside the inflatable balloon 11 is a medicine storage bin 12; the inflatable balloon 11 is communicated with an independent reactant bin 13, a first reactant is placed in the inflatable balloon 11, the reactant bin 13 is used for accommodating and placing a second reactant, and when the first reactant contacts with the second reactant, the first reactant reacts to generate gas, so that the inflatable balloon 11 is inflated, and the medicine storage bin 12 is extruded; the drip chamber 1 has a drip tube 14 and an infusion tube 15; one end of the instillation tube 14 is communicated with the medicine storage bin 12, and the other end is used for being connected with a liquid conveying pipeline of the catheter A; one end of the liquid injection pipe 15 is communicated with the medicine storage bin 12, and the other end is used for extending to the outside of the body so as to facilitate the injection of the medicine liquid into the medicine storage bin 12 in the outside of the body.

In the present application, the duodenum mirror and the method of using the same refer to a conventional duodenum mirror, and can extend to the common bile duct sphincter through the mouth, esophagus, stomach, pylorus and duodenum. The guide wire and the use method thereof refer to the guide wire commonly used in vascular interventional operation, but the guide wire passes through the forceps channel or the biopsy pipeline of the duodenoscope, finally passes through the common bile duct sphincter and stretches into the gall bladder through the common bile duct. It will be appreciated that the catheter A of the present application is required to pass along a guidewire through the mouth, esophagus, stomach, pylorus, duodenum, common bile sphincter, common bile duct, and ultimately into the gallbladder, and therefore, it is preferred that the catheter A be a hollow hose.

The gall-stone treatment device can directly send the medicine for dissolving and removing the gall-stone into the gall-stone, can effectively dissolve and remove the gall-stone, and can directly and better play a role in dissolving and removing the gall-stone compared with the existing oral medicine. It will be appreciated that the key to the present application is the construction of the gallstone treatment device, and as for the gallstone removal medicament, reference may be made to the existing gallstone removal scheme, and is not specifically limited herein.

It should also be noted that the drip chamber of the present application is rolled in its initial state, rolled to a size of about one capsule, so that it enters the stomach, and takes the form of a swim ring after being filled with the drug. On the one hand, the swim ring-shaped instillator can avoid being sucked into the duodenum; on the other hand, food can be allowed to pass through the swimming life-buoy and enter the duodenum, namely, the food is not influenced to enter the duodenum normally.

Preferably, the placement system further comprises a catheter B and a fiberscope, wherein the catheter B and the fiberscope are used for extending into the pipeline of the catheter A and extending into the gall bladder along the catheter A so as to facilitate observation of a required examination position; the front end of the conduit B is provided with an openable spherical air bag, a plurality of spray holes are arranged below the air bag, and liquid is conveyed through a pipeline of the conduit B and can be sprayed out by the spray holes; and at least one set of balloon control pipeline is arranged in the pipeline of the catheter B, one end of the balloon control pipeline of the catheter B is communicated with the balloon of the catheter B, and the other end of the balloon control pipeline extends to the external operation end of the catheter B.

It should be noted that, the effect of the conduit B is mainly to solve the problem that the observation lens is blocked by dirt, so that the optical fiber lens can observe the part to be examined clearly, when in use, the optical fiber lens is just located between the spherical air bags of the conduit a and the conduit B, and the jet hole of the conduit B is designed near the side of the optical fiber lens. Therefore, if observation is not performed by using a fiberscope, the catheter a may be used without using the catheter B, and the catheter a may be directly connected to the drip chamber.

Preferably, the device of the present application further comprises a set-down system for use with, the set-down system comprising a gastroscope, biopsy forceps and an electrotome for removing the drip chamber 1 and the catheter a.

It should be noted that the gastroscope, biopsy forceps and electrotome used in the application are conventional gastroscope, biopsy forceps and electrotome. Because the instillator is placed in the stomach when in use, after the instillator is used, a gastroscope and a biopsy forceps can be directly used for grabbing the liquid injection tube of the instillator from the stomach, so that the instillator can be taken out.

The other side of the application discloses the application of the gall-stone treatment device in slow release drug delivery of pancreas or liver.

It should be noted that the key point of the gall-stone therapeutic device of the present application is that the catheter a is inserted into the portion to be treated in advance and then administered by using a drip chamber with a special design, and it is understood that the catheter a may be inserted into the content of the gall bladder to administer the gall-stone removing drug, or inserted into other portions to administer the corresponding drug, such as pancreas or liver, and the specific drug is not limited herein.

The application also discloses a using method of the gall-stone therapeutic device, which comprises the following steps that firstly, the duodenoscope is stretched into the common bile duct sphincter through the mouth cavity, the guide wire is stretched into along the forceps channel or the biopsy pipeline of the duodenoscope, passes through the common bile duct sphincter, passes through the common bile duct and stretches into the gall bladder;

Removing the duodenoscope, and leaving a guide wire with one end in the gall bladder and the other end outside the body;

then, the catheter A is sleeved into the guide wire, the catheter A extends into the gall bladder through the oral cavity and along the guide wire, after the catheter A extends into the gall bladder, the guide wire is removed, and the catheter A with one end in the gall bladder and the other end outside the body is left, wherein the end of the catheter A outside the body is the external operation end of the catheter A;

In the dissolution treatment system, the instillator 1 is in an initial coiled shape, the instillator pipe 14 of the instillator is communicated with the liquid conveying pipeline at the external operation end of the catheter A outside the body, and then the coiled instillator 1 and the catheter A extend into the stomach, and the liquid injection pipe 15 of the instillator 1 is left outside the body; wherein, in one implementation of the application, the coiled drip chamber 1 is only about one capsule size, can be directly swallowed into the stomach, and can also be fed into the stomach by other auxiliary devices;

Finally, the liquid medicine is injected into the medicine storage bin 12 of the instillator 1 through the liquid injection pipe 15, the instillator 1 is expanded to be in a swimming life-buoy shape, the liquid injection pipe 15 is closed, and the liquid injection pipe 15 is integrally sent into the stomach, so that the installation is completed.

Before the gall-stone therapeutic device is used, the catheter A and the instillator are independent, when the gall-stone therapeutic device is used, the catheter A is placed in place in advance, then the catheter A is connected with the instillator in vitro, the instillator is sent into the stomach, then medicines are injected, and finally the liquid injection pipe 15 is sealed and sent into the stomach, so that the whole device is installed. Then, according to the design, the reactant bin 13 automatically and slowly releases the second reactant into the inflatable balloon 11, so that the second reactant contacts and reacts with the first reactant to generate gas, the inflatable balloon 11 is inflated, the medicine storage bin 12 is extruded, the medicine liquid is extruded by the instillation tube 14, and the medicine liquid is injected into the gall bladder through the liquid conveying pipeline of the catheter A.

Preferably, before the guide wire is removed, the balloon control pipeline of the catheter A is used for inflating the spherical balloon at the front end of the catheter A, and then the guide wire is removed again.

It will be appreciated that the removal of the guide wire, in order to avoid the guide wire carrying out the catheter a, thus inflating the balloon at the front end of the catheter a, serves to locate the catheter a.

Preferably, before the instillation tube 14 is communicated with the liquid delivery line of the extracorporeal operation end of the catheter A, the catheter B and the fiberscope are stretched into the pipeline of the catheter A, and stretched into the gall bladder along the catheter A, and the required examination position is observed, specifically, after the catheter B is stretched out of the catheter A, the spherical balloon of the catheter A and the balloon of the catheter B are opened; spraying clear water or physiological saline through the conduit B, and pumping the clear water or physiological saline out of the conduit A, and circulating until the optical fiber lens can clearly observe, so as to solve the problem that the observation lens is blocked by dirt; after the observation is completed, the balloon of the catheter B is closed, the catheter B and the fiberscope are removed, and the catheter a with one end inside the gallbladder and the other end outside the body is left with the catheter a with one end inside the gallbladder and the other end outside the body.

Preferably, after the release of the liquid medicine is completed, the drip chamber 1 is also taken out by adopting a gastroscope, a biopsy forceps and an electrotome, or the drip chamber 1 and the catheter A are taken out, specifically, if the gastroscope stretches into the stomach for observation, if the reaction gas or residual liquid medicine fills the drip chamber 1, the drip chamber is cut by the electrotome from a biopsy hole of the gastroscope, and the gas and/or the liquid medicine are released; then, grasping the infusion tube 15 of the drip chamber 1 from the biopsy hole with a biopsy forceps, and removing the infusion tube 15 together with the gastroscope outside the body; drawing the instillator 1 out of the body by the liquid injection pipe 15, and simultaneously bringing the external operation end of the catheter A out of the body; finally, if necessary, the catheter A is continuously pulled out of the body to finish the dismantling of the gall-stone treatment device.

It can be understood that in the dismantling process, the instillator can be just dismantled, and after the external operation end of the catheter A is brought out of the body, if the administration is further needed, a new instillator can be replaced, and new liquid medicine is injected for administration, so that the catheter A does not need to be taken out, and the step of putting the catheter A is saved; if continued administration is not required, the entire catheter A may be withdrawn through the extracorporeal operating end of the catheter A.

The application has the beneficial effects that:

The gall-stone treatment device can directly send the liquid medicine into the gall bladder, and improves the treatment effect of dissolving and removing gall-stone of the liquid medicine. The medicine liquid is directly fed into the gall bladder, and the instability or potential safety hazard of the administration modes such as oral administration and the like are avoided. In addition, the device disclosed by the application can not influence food to enter the duodenum and normal eating in the whole using process.

Drawings

Fig. 1 is a schematic view of a drip chamber in accordance with an embodiment of the present application;

FIG. 2 is a schematic view showing the structure of the balloon at the front end of the catheter A in different states when the balloon is closed and opened according to the embodiment of the present application;

FIG. 3 is a schematic view of the structure of the external operation end liquid delivery pipeline and the balloon control pipeline of the catheter A according to the embodiment of the application;

FIG. 4 is a schematic diagram of an assembled structure of a catheter A, a catheter B and a fiberscope according to an embodiment of the application;

Fig. 5 is a schematic view of the structure of the gall stone treatment device according to the embodiment of the present application in vivo when in use.

Detailed Description

The non-operative therapy has the advantages that the gallbladder is not required to be resected or dissected, and the integrity of the human body system is not affected; however, the greatest disadvantage of non-operative therapies is that the therapeutic effect is difficult to guarantee. Particularly, the effect of the oral litholytic medicament is difficult to ensure, and the oral medicament needs to pass through the parts of the oral cavity, esophagus, stomach, duodenum and the like, so that the parts are inevitably influenced, and potential safety hazards exist.

Aiming at the characteristics of bending of gall bladder, gall bladder tube, common bile duct, narrow area and the like, the application develops and designs a special device, namely the gall-stone treatment device, which can directly inject the stone dissolving medicine into the gall bladder and can effectively and safely dissolve and remove the gall bladder, common bile duct and other stones.

In the present application, the front end of the catheter A is the end that guides the catheter A to extend into the body, and the external operation end is the end that remains outside the oral cavity after the catheter A extends into the body. In the present application, the first reactant and the second reactant refer to two or two groups of reactants capable of generating gas when in contact; it will be appreciated that for safety reasons the first reactant, the second reactant and the gas produced are preferably safe and harmless to the human body, for example the first reactant and the second reactant are respectively an acidic solution and baking soda, and the gas produced is carbon dioxide, wherein the acidic solution may be gastric acid or hydrochloric acid, or other acidic substances or acidic mixtures which are harmless to the human body.

The application is described in further detail below with reference to specific examples and figures. The following examples are merely illustrative of the present application and should not be construed as limiting the application.

Examples

The gall-stone treatment device comprises a placement system and a dissolution treatment system, wherein the placement system comprises a duodenal mirror, a guide wire and a catheter A; the dissolution therapy system includes a drip chamber that is in the form of a swim ring when in use.

The duodenoscope is a conventional duodenoscope and is used for extending to the common bile duct sphincter through the mouth, esophagus, stomach, pylorus and duodenum. The guide wire is also a common guide wire for vascular interventional operations and is used for passing through a forceps channel or a biopsy pipeline of a duodenoscope, passing through the common bile duct sphincter and extending into the gall bladder through the common bile duct.

The catheter A in the embodiment is a soft hollow tube, is used for being sleeved into a guide wire and extends into the gall bladder along the guide wire; as shown in fig. 2,2 is a catheter a, the outer side of the front end of the catheter a is provided with a spherical air bag 21 capable of controlling opening and closing, and as shown in fig. 3, two sets of pipelines are additionally arranged in the pipeline of the catheter a; one set of pipeline is a liquid conveying pipeline 22, one end of the liquid conveying pipeline extends out of the front end of the catheter A and is used for releasing the liquid medicine so as to release the liquid medicine into the gall bladder, and the other end of the liquid conveying pipeline extends out of the external operation end of the catheter A; the other set of pipeline is an air bag control pipeline 23, one end of the air bag control pipeline is communicated with the spherical air bag, and the other end of the air bag control pipeline extends out of the external operation end of the catheter A.

The dissolving and removing treatment system comprises a drip chamber 1 which is in a swimming ring shape when in use, as shown in figure 1, an independent inflatable balloon 11 is arranged in the drip chamber 1, and a cavity except the inflatable balloon 11 is a medicine storage bin 12; the inflatable balloon 11 is communicated with an independent reactant bin 13, a first reactant is placed in the inflatable balloon 11, a second reactant is placed in the reactant bin 13, and the first reactant reacts to generate gas when contacting with the second reactant, so that the inflatable balloon 11 is inflated, and the medicine storage bin 12 is extruded; the drip chamber 1 has a drip tube 14 and an infusion tube 15; one end of the instillation tube 14 is communicated with the medicine storage bin 12, and the other end is used for being connected with a liquid conveying pipeline of the catheter A; one end of the liquid injection pipe 15 is communicated with the medicine storage bin 12, and the other end is used for extending to the outside of the body so as to facilitate the injection of the medicine liquid into the medicine storage bin 12 in the outside of the body. The inflatable balloon 11 is isolated by the isolating film 111 on the side close to the drip tube 14, so that the inflatable balloon 11 does not expand to the part of the drip tube 14, and the inflatable balloon 11 is prevented from closing the drip tube 14, and in fact, the inflatable balloon 11 is controlled to expand along one direction of the swim ring-shaped drip chamber. The drip chamber 1 of this example is initially in a rolled state prior to administration of the medical fluid, and is approximately one capsule size as a whole, except for the drip tube 14 and the infusion tube 15.

In one implementation of this example, the first reactant is baking soda, the first reactant is gastric acid, the second reactant is sodium bicarbonate, and the second reactant reacts with the baking soda to generate carbon dioxide after entering the inflatable balloon through the reactant bin, so that the inflatable balloon is inflated.

In order to facilitate observation of the desired examination site, in a modification of this embodiment, the placement system further includes a catheter B and a fiberscope, as shown in fig. 4, in the drawing, 21 is a spherical balloon of the catheter a, 42 is the catheter B, 43 is the fiberscope, 421 is the balloon of the catheter B, 422 is the jet orifice of the catheter B, and the catheter B and the fiberscope are used for extending into the pipe of the catheter a and extending into the gallbladder along the catheter a so as to facilitate observation of the desired examination site; the front end of the conduit B is provided with an openable spherical air bag, a plurality of spray holes are arranged below the air bag, and liquid is conveyed through a pipeline of the conduit B and can be sprayed out by the spray holes; and a set of air bag control pipeline is arranged in the pipeline of the conduit B, one end of the air bag control pipeline of the conduit B is communicated with the air bag of the conduit B, and the other end of the air bag control pipeline extends to the external operation end of the conduit B.

In addition, in order to facilitate disassembly, the gall-stone treatment device of the embodiment further comprises a matched removing system, wherein the removing system comprises a gastroscope, a biopsy forceps and an electrotome and is used for taking out the instillator 1 and the catheter A. Wherein, the gastroscope, the biopsy forceps and the electrotome are all conventional gastroscope, biopsy forceps and electrotome. When the device of the embodiment is disassembled, the instillator is placed in the stomach, so that after the device is used, the gastroscope and the biopsy forceps can be directly adopted to grasp the liquid injection pipe of the instillator from the stomach, the liquid injection pipe is pulled out along with the gastroscope, then the instillator is pulled out, and finally the catheter A is pulled out, so that the device is disassembled, and the device is simple and convenient to use.

In order to better explain the gall-stone treatment device of the embodiment, the embodiment provides a detailed use method, which specifically comprises the following steps:

1. Placing step

A. extending the duodenoscope through the mouth, esophagus, stomach, pylorus and duodenum to the common bile duct sphincter;

b. The guide wire passes through the sphincter to enter the common bile duct through the forceps channel or the biopsy pipeline and then goes into the gall bladder;

b1: if it is felt that there is difficulty in accessing the catheter A into the common bile duct sphincter or it is difficult to insert the catheter A, conventional endoscopic retrograde cholangiography (abbreviated ERCP) can be performed by using a duodenoscope to cut the common bile duct sphincter;

b2: in addition, conventional angiography (abbreviated DSA) may be used to observe the guidewire trace during guidewire advancement;

c. After the guide wire is stretched into the gall bladder, the duodenal mirror is slowly removed, the guide wire is left, and at the moment, one end of the guide wire is positioned in the gall bladder and one end of the guide wire is positioned outside the body;

d. The catheter A is sleeved into a guide wire and enters the gall bladder through the oral cavity, the esophagus, the stomach, the pylorus, the duodenum, the sphincter and the common bile duct;

e. Slowly removing the guide wire, wherein one end of the guide tube A is positioned in the gall bladder, and one end of the guide tube A is positioned outside the body;

When the guide wire is removed, in order to prevent the guide wire from being pulled outwards by the guide wire, an air bag control pipeline is controlled at the external operation end of the guide wire A, so that the spherical air bag is opened, the air bag control pipeline is sealed, air leakage is avoided, the spherical air bag is maintained in an opened state, and the front end of the guide wire A is stabilized in the gall bladder;

f. if DSA is not used, observing the required examination part by adopting a fiber optic mirror, and pushing the fiber optic mirror and the catheter B into the catheter A to the front end of the catheter A; the fiberoptic is easily obscured by material in the common bile duct, and is therefore observed as follows:

① After the optical fiber mirror and the catheter B are stretched into the appointed position, opening a balloon at the front end of the catheter B;

② Introducing clear water or physiological saline into the catheter B, spraying out the clear water or physiological saline from the spraying hole of the catheter B, cleaning the optical fiber mirror, and simultaneously extracting the clear water or the physiological saline through the catheter A to extract the clear water or the physiological saline in the body;

③ Continuously introducing and extracting clear water or normal saline until the optical fiber mirror can clearly observe;

④ Observing the required examination part;

⑤ Closing the air sac at the front end of the catheter B, and removing the fiberscope and the catheter B;

Finally, after the observation, only one end of the catheter A is left in the gall bladder and the other end is outside the body. If the examination part is not required to be observed, the step f is not required, and the subsequent steps can be directly carried out after the guide wire is removed.

2. Instillation treatment step

The initial state of the instillator outside the body is a winding state, namely the whole instillator is wound into a capsule size, the capsule is provided with two pipes, one is a shorter instillator pipe and the other is a longer liquid injection pipe, and the specific using method is as follows:

1) A liquid delivery line of the catheter A left outside the body is communicated with a instillation tube of the instillator;

2) After connection is completed, the instillator and the conduit A are left at one end outside the body, finger stomach is pushed through the whole mouth cavity, and one end of a liquid injection pipe of the instillator is left outside the mouth cavity;

3) The medicine liquid which is dissolved by the liquid injection pipe and removes the stones is filled in the medicine storage bin of the instillator, so that the medicine storage bin is expanded to be in a swimming ring shape, and then the liquid injection pipe is sealed after being tied up and pushed into the stomach.

At this time, the drip chamber is opened in the stomach in the shape of a swim ring, and the total internal volume is a certain value.

A. the second reactant in the reactant chamber slowly overflows into the inflatable balloon 11 and reacts with the first reactant in the inflatable balloon 11 to generate gas.

B. The generated gas expands the inflatable saccule, occupies the volume of the medicine storage bin, injects the medicine liquid in the medicine storage bin into the liquid conveying pipeline of the catheter A through the instillation pipe, continuously inputs the medicine liquid into the gall bladder, and enables the medicine liquid to directly contact with the knot in the gall bladder to dissolve and remove gall stones; as shown in fig. 5, a dashed line 51 in fig. 5 is a flow curve of the drug solution along with the catheter a. In fig. 5, 1 denotes a drip chamber, 52 denotes esophagus, 53 denotes stomach, 54 denotes pancreatic duct, 55 denotes common bile duct sphincter, 56 denotes duodenum, 57 denotes common bile duct, 58 denotes gall bladder, 59 denotes liver, and 50 denotes gall bladder stone.

Generally, according to different liquid medicines adopted, the calculus can be dissolved and removed after 10-50 hours, and the swim ring-shaped instillator can not only prevent the calculus from being sucked into the duodenum, but also allow food to normally enter the duodenum without influencing normal feeding.

3. Removing

After the calculus is dissolved, the gall-stone treatment device of the example needs to be removed, and the specific steps are as follows:

a. Extending the gastroscope into the stomach for observation, and if the reaction gas or residual liquid medicine fills the instillator, cutting the instillator from the biopsy hole by an electrotome to shrink the instillator;

b. Grasping a liquid injection tube of the instillator from the biopsy hole with a biopsy forceps, and simultaneously removing the liquid injection tube and the gastroscope from the body;

c. dragging the liquid injection pipe to drag the instillator out of the body, and pulling the external operation end of the catheter A out of the body;

d. and controlling the spherical air bag to be closed from the external operation end of the catheter A, and then drawing the catheter A out of the body to finish the disassembly.

The gall-stone treatment device can directly send the liquid medicine into the gall bladder, improves the treatment effect of dissolving and removing the gall-stone by the liquid medicine, and has high safety. In addition, in the whole using process, food can not enter the duodenum and normal eating is not influenced. The gall-stone treatment device of the embodiment can be used for administration of pancreas, liver and the like according to the specific extending-in position of the catheter A and different medicines adopted specifically, and can control the expansion speed of the inflatable balloon of the instillator so as to achieve the effect of controlling the slow release of the medicines.

The foregoing is a further detailed description of the application in connection with specific embodiments, and it is not intended that the application be limited to such description. It will be apparent to those skilled in the art that several simple deductions or substitutions may be made without departing from the spirit of the application, and these should be considered to be within the scope of the application.

Claims (4)

1. A device for treating gall-stone, characterized in that: comprises a placement system and a dissolving treatment system, wherein the placement system comprises a duodenoscope, a guide wire and a catheter A;

The duodenoscope is used for extending to the common bile duct sphincter through the mouth, esophagus, stomach, pylorus and duodenum; the guide wire is used for passing through a forceps channel or a biopsy pipeline of the duodenum scope, passing through the common bile duct sphincter and extending into the gall bladder through the common bile duct;

the catheter A is used for being sleeved into the guide wire and extending into the gall bladder along the guide wire; the outer side of the front end of the conduit A is provided with a spherical air bag which can be controlled to open and close, and at least two sets of pipelines are additionally arranged in the pipeline of the conduit A; one set of pipeline is a liquid conveying pipeline, one end of the liquid conveying pipeline extends to the front end of the catheter A and is used for releasing the liquid medicine in the gall bladder, and the other end of the liquid conveying pipeline extends out of the external operation end of the catheter A; the other set of pipeline is an air bag control pipeline, one end of the air bag control pipeline is communicated with the spherical air bag, and the other end of the air bag control pipeline extends out of the external operation end of the catheter A;

The dissolving and removing treatment system comprises a instillator (1) which is in a swimming life-buoy shape when in use, an independent inflatable balloon (11) is arranged in the instillator (1), and a cavity except the inflatable balloon (11) is a medicine storage bin (12); the inflatable balloon (11) is communicated with an independent reactant bin (13), a first reactant is placed in the inflatable balloon (11), the reactant bin (13) is used for accommodating and placing a second reactant, and the first reactant reacts to generate gas when contacting with the second reactant, so that the inflatable balloon (11) is inflated, and the medicine storage bin (12) is extruded;

The drip chamber (1) has a drip tube (14) and an infusion tube (15); one end of the instillation tube (14) is communicated with the medicine storage bin (12), and the other end of the instillation tube is used for being connected with an external operation end of the liquid conveying pipeline of the catheter A; one end of the liquid injection pipe (15) is communicated with the medicine storage bin (12), and the other end of the liquid injection pipe is used for extending to the outside of the body so as to facilitate the injection of the liquid medicine into the medicine storage bin (12) in the outside of the body.

2. The apparatus according to claim 1, wherein: one end of the liquid conveying pipeline can also extend out of the front end of the conduit A.

3. The apparatus according to claim 1, wherein: the placement system also comprises a catheter B and a fiber optic mirror, wherein the catheter B and the fiber optic mirror are used for extending into the pipeline of the catheter A and extending into the gall bladder along the catheter A so as to facilitate the observation of a required examination position; the front end of the conduit B is provided with an openable spherical air bag, a plurality of spray holes are arranged below the air bag, and liquid is conveyed through a pipeline of the conduit B and can be sprayed out from the spray holes; and at least one set of balloon control pipeline is arranged in the pipeline of the catheter B, one end of the balloon control pipeline of the catheter B is communicated with the balloon of the catheter B, and the other end of the balloon control pipeline extends to the external operation end of the catheter B.

4. The apparatus according to claim 1, wherein: the medical drip chamber also comprises a matched removing system, wherein the removing system comprises a gastroscope, a biopsy forceps and an electrotome and is used for taking out the drip chamber (1) and the catheter A.