CN108801752B - A sample loading device and a sample driving device - Google Patents
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- 238000012360 testing method Methods 0.000 claims abstract description 67
- 239000011324 bead Substances 0.000 claims description 27
- 238000003325 tomography Methods 0.000 abstract description 8
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- 238000009434 installation Methods 0.000 abstract description 6
- 230000003287 optical effect Effects 0.000 description 8
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
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Abstract
本发明公开了一种样品装载装置以及样品驱动装置，样品装载装置包括样品固定模块、试管模块以及装载台，装载台中部位置设有阶梯通孔，阶梯通孔内设有第一环形凸台以及第二环形凸台，样品固定模块包括圆形面板以及直棒，试管模块磁性扣合在第二环形凸台上表面，样品固定模块的面板磁性扣合在第一环形凸台上表面，直棒可插入到试管模块内部。本发明创造通过磁力吸合方式实现试管模块与装载台之间、样品固定模块与装载台之间的安装连接，在装置应用过程中提高了操作的方便性和精确性，提高了测量的精确度。样品驱动装置通过样品装载装置将待测样品安装在旋转组件上，提高应用过程中装置操作的便捷性，提高层析成像测量的准确度。
The invention discloses a sample loading device and a sample driving device. The sample loading device includes a sample fixing module, a test tube module and a loading platform. The loading platform is provided with a stepped through hole in the middle, and a first annular boss is provided in the stepped through hole. The second annular boss, the sample fixing module includes a circular panel and a straight rod. The test tube module is magnetically fastened to the upper surface of the second annular boss. The panel of the sample fixing module is magnetically fastened to the upper surface of the first annular boss. The straight rod Can be inserted inside the test tube module. The invention realizes the installation connection between the test tube module and the loading platform and between the sample fixing module and the loading platform through magnetic attraction, which improves the convenience and accuracy of operation and improves the accuracy of measurement during the application of the device. . The sample driving device installs the sample to be tested on the rotating assembly through the sample loading device, which improves the convenience of device operation during application and improves the accuracy of tomography measurement.
Description
技术领域Technical field
本发明涉及光学投影层析成像装置技术领域，更加具体地说涉及一种应用于光学投影层析成像系统的样品装载装置以及样品驱动装置。The present invention relates to the technical field of optical projection tomography devices, and more specifically to a sample loading device and a sample driving device used in an optical projection tomography system.
背景技术Background technique
光学投影层析三维成像（optical projection tomography）是一种新型的小型生物标本三维成像技术，这种三维成像技术通过光学清除剂清洁或采用透明样品，利用紫外线、可见光和近红外光谱，通过样品传输光子来计算三维结构。Optical projection tomography is a new three-dimensional imaging technology for small biological specimens. This three-dimensional imaging technology uses ultraviolet, visible light and near-infrared spectra to transmit through the sample by cleaning it with optical clearers or using transparent samples. photons to calculate three-dimensional structures.
目前，光学投影层析成像系统的样品装载方案，主要是利用开孔橡胶塞，将样本固定装置穿过橡胶塞上的通孔，样本固定装置上固定有待测样品，最后将橡胶塞塞入试管端口处，将待测样品置于试管内部，最后将整个试管安放在成像系统上进行测量。At present, the sample loading scheme of the optical projection tomography system mainly uses an open-hole rubber plug. The sample fixing device is passed through the through hole in the rubber plug. The sample to be measured is fixed on the sample fixing device, and finally the rubber plug is inserted. At the test tube port, place the sample to be tested inside the test tube, and finally place the entire test tube on the imaging system for measurement.
现有的样品装载方案，好处在于所需要的装载组件简单，成本低，但是缺点在于橡胶塞容易受到环境或使用次数的影响而老化，导致橡胶塞通孔变形，容易使试管内部的待测样品偏移中心位置，而且将橡胶塞塞入试管端口后，橡胶塞或多或少都会存在一定程度的倾斜，这也容易使试管内部的待测样品偏移中心位置，在试管转动过程中待测样品容易脱离景深范围，影响投影数据的准确度。The advantage of the existing sample loading scheme is that the required loading components are simple and low cost, but the disadvantage is that the rubber stopper is easily affected by the environment or the number of uses and ages, causing the through hole of the rubber stopper to deform, which can easily damage the sample to be tested inside the test tube. Offset from the center position, and after inserting the rubber stopper into the test tube port, the rubber stopper will be more or less tilted to a certain extent, which will also easily cause the sample to be tested inside the test tube to shift from the center position, and the test tube will be tested during the rotation process. The sample easily leaves the depth of field range, affecting the accuracy of the projection data.
发明内容Contents of the invention
本发明要解决的技术问题是：由于橡胶塞自身存在的形变以及将橡胶塞装载到试管上时橡胶塞所存在的倾斜，导致试管内部的待测样品偏移中心位置。The technical problem to be solved by the present invention is that due to the deformation of the rubber stopper itself and the inclination of the rubber stopper when loading the rubber stopper onto the test tube, the sample to be tested inside the test tube deviates from the center position.
本发明解决其技术问题的解决方案是：The solution of the present invention to solve its technical problems is:
一种应用于光学投影层析成像系统的样品装载装置，包括样品固定模块、试管模块以及装载台，所述装载台中部位置设有阶梯通孔，所述阶梯通孔内自上而下依次设有第一环形凸台以及第二环形凸台，所述第一环形凸台与第二环形凸台圆心共点，所述第二环形凸台高度大于第一环形凸台高度，所述样品固定模块包括圆形面板以及直棒，应用时待测样品固定在直棒底部，所述直棒安装在面板底部圆心位置处，所述试管模块磁性扣合在第二环形凸台上表面，所述样品固定模块的面板磁性扣合在第一环形凸台上表面，所述直棒可插入到试管模块内部。A sample loading device used in an optical projection tomography system, including a sample fixing module, a test tube module and a loading platform. The loading platform is provided with a stepped through hole in the middle, and the stepped through hole is provided with a ladder from top to bottom. There is a first annular boss and a second annular boss, the first annular boss and the second annular boss have the same center point, the height of the second annular boss is greater than the height of the first annular boss, and the sample is fixed The module includes a circular panel and a straight rod. During application, the sample to be tested is fixed at the bottom of the straight rod. The straight rod is installed at the center of the bottom of the panel. The test tube module is magnetically fastened to the upper surface of the second annular boss. The panel of the sample fixing module is magnetically fastened to the upper surface of the first annular boss, and the straight rod can be inserted into the inside of the test tube module.
作为上述技术方案的进一步改进，所述试管模块包括试管以及试管固定环，所述试管固定环扣合在第二环形凸台上表面；所述试管固定环的壁厚自上而下逐渐变大，所述试管包括管体与设置在管体顶部的限位部，所述试管固定环的内环尺寸与试管的管体尺寸相匹配，所述限位部与试管固定环内侧壁面接触。As a further improvement of the above technical solution, the test tube module includes a test tube and a test tube fixing ring. The test tube fixing ring is fastened on the upper surface of the second annular boss; the wall thickness of the test tube fixing ring gradually increases from top to bottom. , the test tube includes a tube body and a limiting portion arranged on the top of the tube body, the inner ring size of the test tube fixing ring matches the size of the test tube body, and the limit portion is in contact with the inner wall surface of the test tube fixing ring.
作为上述技术方案的进一步改进，所述第二环形凸台上表面设有多个第一磁珠，所述试管固定环底部设有多个与第一磁珠相匹配的第一磁性凹位，所述试管固定环扣合在第二环形凸台时，所述第一磁珠与第一磁性凹位磁性连接。As a further improvement of the above technical solution, a plurality of first magnetic beads are provided on the upper surface of the second annular boss, and a plurality of first magnetic recesses matching the first magnetic beads are provided on the bottom of the test tube fixing ring. When the test tube fixing ring is engaged with the second annular boss, the first magnetic beads are magnetically connected to the first magnetic concave position.
作为上述技术方案的进一步改进，所述第一环形凸台上表面设有多个第二磁性凹位，所述样品固定模块的面板底部设有多个与第二磁性凹位相匹配的第二磁珠，所述样品固定模块的面板底部扣合在第一环形凸台上表面时，所述第二磁珠与第二磁性凹位磁性连接。As a further improvement of the above technical solution, a plurality of second magnetic recesses are provided on the upper surface of the first annular boss, and a plurality of second magnetic recesses matching the second magnetic recesses are provided on the bottom of the panel of the sample fixing module. beads, when the bottom of the panel of the sample fixing module is fastened to the upper surface of the first annular boss, the second magnetic beads are magnetically connected to the second magnetic concave position.
本发明的有益效果是：本发明创造通过磁力吸合方式实现试管模块与装载台之间、样品固定模块与装载台之间的安装连接，避免了现有技术方案中利用橡胶塞老化而产生形变的技术问题，在装置应用过程中提高了操作的方便性和精确性，提高了测量的精确度。The beneficial effects of the present invention are: the invention realizes the installation connection between the test tube module and the loading platform and between the sample fixing module and the loading platform through magnetic attraction, avoiding the deformation caused by the aging of the rubber stopper in the existing technical solution. The technical problems are solved, and the convenience and accuracy of operation are improved during the application of the device, and the accuracy of measurement is improved.
本发明同时还公开了一种样品驱动装置，包括升降组件、旋转组件、三维调节组件以及上述样品装载装置，所述旋转组件安装在升降组件上，所述三维调节组件安装在旋转组件上，所述样品装载装置安装在三维调节组件上。The invention also discloses a sample driving device, which includes a lifting component, a rotating component, a three-dimensional adjusting component and the above-mentioned sample loading device. The rotating component is installed on the lifting component, and the three-dimensional adjusting component is installed on the rotating component. The sample loading device is installed on the three-dimensional adjustment assembly.
作为上述技术方案的进一步改进，所述装载台上表面设有多个第三磁珠，多个所述第三磁珠以装载台中心为圆心呈环形阵列分布，所述三维调节组件底部设有多个与第三磁珠相匹配的第三磁性凹位，所述样品装载装置安装在三维调节组件底部时，所述第三磁珠与第三磁性凹位磁性连接。As a further improvement of the above technical solution, a plurality of third magnetic beads are provided on the upper surface of the loading platform, and the plurality of third magnetic beads are distributed in an annular array with the center of the loading platform as the center, and the bottom of the three-dimensional adjustment component is provided with There are a plurality of third magnetic recesses matching the third magnetic beads. When the sample loading device is installed at the bottom of the three-dimensional adjustment assembly, the third magnetic beads are magnetically connected to the third magnetic recesses.
本发明的有益效果是：本发明创造通过样品装载装置将待测样品安装在旋转组件上，并通过三维调节组件调节样品装载装置的位置，保证待测样品准确地固定在旋转组件的转动中心轴位置，提高应用过程中装置操作的便捷性，提高层析成像测量的准确度。The beneficial effects of the present invention are: the present invention installs the sample to be tested on the rotating component through the sample loading device, and adjusts the position of the sample loading device through the three-dimensional adjustment component to ensure that the sample to be tested is accurately fixed on the rotation center axis of the rotating component position, improving the convenience of device operation during application and improving the accuracy of tomographic imaging measurements.
附图说明Description of the drawings
为了更清楚地说明本发明实施例中的技术方案，下面将对实施例描述中所需要使用的附图作简单说明。显然，所描述的附图只是本发明的一部分实施例，而不是全部实施例，本领域的技术人员在不付出创造性劳动的前提下，还可以根据这些附图获得其他设计方案和附图。In order to explain the technical solutions in the embodiments of the present invention more clearly, the drawings needed to be used in the description of the embodiments will be briefly described below. Obviously, the described drawings are only some of the embodiments of the present invention, not all embodiments. Those skilled in the art can also obtain other design solutions and drawings based on these drawings without exerting creative efforts.
图1是本发明创造的样品装载装置结构示意图；Figure 1 is a schematic structural diagram of the sample loading device created by the present invention;
图2是本发明创造的样品驱动装置结构示意图。Figure 2 is a schematic structural diagram of the sample driving device created by the present invention.
具体实施方式Detailed ways
以下将结合实施例和附图对本发明的构思、具体结构及产生的技术效果进行清楚、完整的描述，以充分地理解本发明的目的、特征和效果。显然，所描述的实施例只是本发明的一部分实施例，而不是全部实施例，基于本发明的实施例，本领域的技术人员在不付出创造性劳动的前提下所获得的其他实施例，均属于本发明保护的范围。另外，文中所提到的所有联接/连接关系，并非单指构件直接相接，而是指可根据具体实施情况，通过添加或减少联接辅件，来组成更优的联接结构。本发明创造中的各个技术特征，在不互相矛盾冲突的前提下可以交互组合。The following will clearly and completely describe the concept, specific structure and technical effects of the present invention in conjunction with the embodiments and drawings to fully understand the purpose, features and effects of the present invention. Obviously, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, other embodiments obtained by those skilled in the art without exerting creative efforts are all protection scope of the present invention. In addition, all the connections/connection relationships mentioned in the article do not only refer to the direct connection of components, but refer to the fact that a better connection structure can be formed by adding or reducing connection accessories according to the specific implementation conditions. Various technical features in the invention can be combined interactively without conflicting with each other.
参照图1，针对现有技术中光学投影层析成像系统的样品装载方案的缺陷，本发明创造公开了一种应用于光学投影层析成像系统的样品装载装置，包括样品固定模块、试管模块以及装载台1，所述装载台1中部位置设有阶梯通孔11，所述阶梯通孔11内自上而下依次设有第一环形凸台12以及第二环形凸台13，所述第一环形凸台12与第二环形凸台13圆心共点，所述第二环形凸台13高度大于第一环形凸台12高度，即第一环形凸台12所围成的圆的半径大于第二环形凸台13所围成的圆的半径，所述样品固定模块包括圆形面板21以及直棒22，应用时待测样品固定在直棒22底部，所述直棒22安装在面板21底部圆心位置处，所述试管模块磁性扣合在第二环形凸台13上表面，所述样品固定模块的面板21磁性扣合在第一环形凸台12上表面，所述直棒22可插入到试管模块内部。具体地，本发明创造通过磁力吸合方式实现试管模块与装载台1之间、样品固定模块与装载台1之间的安装连接，避免了现有技术方案中利用橡胶塞老化而产生形变的技术问题，在装置应用过程中提高了操作的方便性和精确性，提高了测量的精确度。Referring to Figure 1, in view of the defects of the sample loading scheme of the optical projection tomography system in the prior art, the present invention creates and discloses a sample loading device for the optical projection tomography system, which includes a sample fixing module, a test tube module and a Loading platform 1, the loading platform 1 is provided with a stepped through hole 11 in the middle position, and a first annular boss 12 and a second annular boss 13 are provided in the stepped through hole 11 from top to bottom. The circular centers of the annular boss 12 and the second annular boss 13 are at the same point. The height of the second annular boss 13 is greater than the height of the first annular boss 12. That is, the radius of the circle enclosed by the first annular boss 12 is greater than that of the second annular boss 12. The radius of the circle enclosed by the annular boss 13. The sample fixing module includes a circular panel 21 and a straight rod 22. When used, the sample to be tested is fixed at the bottom of the straight rod 22. The straight rod 22 is installed at the center of the bottom of the panel 21. At the position, the test tube module is magnetically fastened to the upper surface of the second annular boss 13, the panel 21 of the sample fixing module is magnetically fastened to the upper surface of the first annular boss 12, and the straight rod 22 can be inserted into the test tube. inside the module. Specifically, the present invention realizes the installation connection between the test tube module and the loading platform 1 and between the sample fixing module and the loading platform 1 through magnetic attraction, avoiding the technology of using rubber plugs to cause deformation due to aging in the existing technical solutions. Problem, the convenience and accuracy of operation are improved during the application of the device, and the accuracy of measurement is improved.
进一步作为优选的实施方式，本发明创造具体实施方式，所述试管模块包括试管31以及试管固定环32，所述试管固定环32扣合在第二环形凸台13上表面；所述试管固定环32的壁厚自上而下逐渐变大，所述试管31包括管体312与设置在管体312顶部的限位部311，所述试管固定环32的内环尺寸与试管31的管体312尺寸相匹配，所述限位部311与试管固定环32内侧壁面接触。更具体地，所述试管31的限位部311与试管固定环32内侧壁之间的接触面均呈弧形结构，通过上述设置有效提高应用过程中装置操作的便捷性以及试管31的稳定性。As a further preferred embodiment, the present invention creates a specific embodiment in which the test tube module includes a test tube 31 and a test tube fixing ring 32, and the test tube fixing ring 32 is fastened to the upper surface of the second annular boss 13; the test tube fixing ring The wall thickness of the test tube 32 gradually increases from top to bottom. The test tube 31 includes a tube body 312 and a limiting portion 311 provided on the top of the tube body 312. The inner ring size of the test tube fixing ring 32 is consistent with the tube body 312 of the test tube 31. The dimensions match, and the limiting portion 311 is in contact with the inner wall surface of the test tube fixing ring 32 . More specifically, the contact surface between the limiting portion 311 of the test tube 31 and the inner wall of the test tube fixing ring 32 is in an arc-shaped structure. The above arrangement effectively improves the convenience of device operation and the stability of the test tube 31 during the application process. .
进一步作为优选的实施方式，本发明创造具体实施方式，所述第二环形凸台13上表面设有多个第一磁珠14，所述试管固定环32底部设有多个与第一磁珠14相匹配的第一磁性凹位，所述试管固定环32扣合在第二环形凸台13时，所述第一磁珠14与第一磁性凹位磁性连接。具体地，所述试管固定环32扣合在第二环形凸台13后，试管固定环32底部与第二环形凸台13上表面相贴合，所述试管固定环32顶部与第一环形凸台12上表面齐平，保证了试管固定环32与装载台1之间安装牢固性的同时，还方便使用者对其进行拆卸。As a further preferred embodiment, the present invention creates a specific embodiment in which a plurality of first magnetic beads 14 are provided on the upper surface of the second annular boss 13, and a plurality of first magnetic beads 14 are provided on the bottom of the test tube fixing ring 32. 14 matches the first magnetic concave position. When the test tube fixing ring 32 is engaged with the second annular boss 13, the first magnetic beads 14 are magnetically connected to the first magnetic concave position. Specifically, the test tube fixing ring 32 is fastened behind the second annular boss 13, the bottom of the test tube fixing ring 32 is in contact with the upper surface of the second annular boss 13, and the top of the test tube fixing ring 32 is in contact with the first annular boss 13. The upper surface of the platform 12 is flush, which not only ensures the firmness of the installation between the test tube fixing ring 32 and the loading platform 1, but also facilitates the user's disassembly.
进一步作为优选的实施方式，本发明创造具体实施方式，所述第一环形凸台12上表面设有多个第二磁性凹位15，所述样品固定模块的面板21底部设有多个与第二磁性凹位15相匹配的第二磁珠，所述样品固定模块的面板21底部扣合在第一环形凸台12上表面时，所述第二磁珠与第二磁性凹位15磁性连接。具体地，所述样品固定模块的面板21底部扣合在第一环形凸台12上表面后，面板21底部与第一环形凸台12上表面相贴合，面板21顶部与装载台1上表面齐平，保证了样品固定模块与装载台1之间安装牢固性的同时，还方便使用者对其进行拆卸。As a further preferred embodiment, the present invention creates a specific embodiment in which a plurality of second magnetic recesses 15 are provided on the upper surface of the first annular boss 12, and a plurality of second magnetic recesses 15 are provided on the bottom of the panel 21 of the sample fixing module. The second magnetic bead matches the two magnetic recessed positions 15. When the bottom of the panel 21 of the sample fixing module is fastened to the upper surface of the first annular boss 12, the second magnetic bead is magnetically connected to the second magnetic recessed position 15. . Specifically, after the bottom of the panel 21 of the sample fixing module is fastened to the upper surface of the first annular boss 12, the bottom of the panel 21 is in contact with the upper surface of the first annular boss 12, and the top of the panel 21 is in contact with the upper surface of the loading platform 1. Flush, which not only ensures the firmness of the installation between the sample fixing module and the loading platform 1, but also facilitates the user's disassembly.
参照图2，本发明创造同时还公开了一种样品驱动装置，包括升降组件4、旋转组件5、三维调节组件6以及上述样品装载装置，所述旋转组件5安装在升降组件4上，所述三维调节组件6安装在旋转组件5上，所述样品装载装置安装在三维调节组件6上。具体地，所述升降组件4用于调节待测样品的高度，保证在进行层析成像过程中待测样品处于合适的位置，所述旋转组件5用于实现待测样品的转动操作，实现待测样品多角度图像采集操作，所述三维调节组件6用于对待测样品的位置进行细微的调节，保证待测样品位于旋转组件5的转动中心轴上。另外需要说明的是，本发明创造具体实施方式中，所述旋转组件5不是直接安装在升降组件4上的，而是通过一连接构件7实现旋转组件5与升降组件4的安装连接。Referring to Figure 2, the present invention also discloses a sample driving device, which includes a lifting component 4, a rotating component 5, a three-dimensional adjustment component 6 and the above-mentioned sample loading device. The rotating component 5 is installed on the lifting component 4, and the The three-dimensional adjustment assembly 6 is installed on the rotating assembly 5 , and the sample loading device is installed on the three-dimensional adjustment assembly 6 . Specifically, the lifting component 4 is used to adjust the height of the sample to be tested to ensure that the sample to be tested is in an appropriate position during the tomographic imaging process, and the rotating component 5 is used to realize the rotation operation of the sample to be tested to achieve For the multi-angle image acquisition operation of the sample to be tested, the three-dimensional adjustment component 6 is used to finely adjust the position of the sample to be tested to ensure that the sample to be tested is located on the central axis of rotation of the rotating component 5 . In addition, it should be noted that in the specific embodiment of the present invention, the rotating component 5 is not directly installed on the lifting component 4, but is installed and connected to the lifting component 4 through a connecting member 7.
本发明创造通过样品装载装置将待测样品安装在旋转组件5上，并通过三维调节组件6调节样品装载装置的位置，保证待测样品准确地固定在旋转组件5的转动中心轴位置，提高应用过程中装置操作的便捷性，提高层析成像测量的准确度。The invention installs the sample to be tested on the rotating component 5 through the sample loading device, and adjusts the position of the sample loading device through the three-dimensional adjustment component 6 to ensure that the sample to be tested is accurately fixed on the rotation center axis of the rotating component 5, improving application The convenience of device operation during the process improves the accuracy of tomographic imaging measurements.
进一步作为优选的实施方式，本发明创造具体实施方式，所述装载台1上表面设有多个第三磁珠16，多个所述第三磁珠16以装载台1中心为圆心呈环形阵列分布，所述三维调节组件6底部设有多个与第三磁珠16相匹配的第三磁性凹位，所述样品装载装置安装在三维调节组件6底部时，所述第三磁珠16与第三磁性凹位磁性连接。完成扣合后，所述三维调节组件6底部与装载台1上表面相贴合，保证了三维调节组件6与装载台1之间安装牢固性的同时，还方便使用者对其进行拆卸。As a further preferred embodiment, the present invention creates a specific embodiment in which a plurality of third magnetic beads 16 are provided on the upper surface of the loading platform 1, and the plurality of third magnetic beads 16 form an annular array with the center of the loading platform 1 as the center. Distribution, the bottom of the three-dimensional adjustment assembly 6 is provided with a plurality of third magnetic recesses that match the third magnetic beads 16. When the sample loading device is installed at the bottom of the three-dimensional adjustment assembly 6, the third magnetic beads 16 and The third magnetic concave position is magnetically connected. After the buckling is completed, the bottom of the three-dimensional adjustment component 6 fits the upper surface of the loading platform 1, which ensures the firmness of the installation between the three-dimensional adjustment component 6 and the loading platform 1 and also facilitates the user's disassembly.
以上对本发明的较佳实施方式进行了具体说明，但本发明创造并不限于所述实施例，熟悉本领域的技术人员在不违背本发明精神的前提下还可作出种种的等同变型或替换，这些等同的变型或替换均包含在本申请权利要求所限定的范围内。The preferred embodiments of the present invention have been specifically described above, but the present invention is not limited to the embodiments. Those skilled in the art can also make various equivalent modifications or substitutions without violating the spirit of the present invention. These equivalent modifications or substitutions are included within the scope defined by the claims of this application.
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