CN108744103A - A kind of filtering device for blood dialysis with blood filtering function - Google Patents

Abstract

The invention belongs to the technical field of medical equipment, and discloses a hemodialysis filtration device with hemofiltration function, including a dialyzer, a blood collection tube and a return tube connected to the dialyzer, and a replacement fluid pipeline connected to the blood collection tube The dialyzer is provided with a dialysate inlet and a waste liquid outlet; the waste liquid pipeline is connected with a waste liquid inlet, and the waste liquid inlet matches the waste liquid outlet; the dialysate pipeline is connected with a dialysate outlet, and the dialysate outlet is connected with the dialysis The liquid inlet is matched; the three-way joint includes a first joint, a second joint and a third joint, the first joint matches the dialysate outlet, the second joint matches the waste liquid outlet, and the third joint matches the waste liquid inlet. The hemodiafiltration device of the present invention, on the basis of conventional hemodiafiltration function, only needs to bypass the external pipeline without changing the working mode of the dialysis machine, and can perform hemodiafiltration while performing hemodiafiltration. Guaranteed to balance and function properly.

Description

A hemodiafiltration device with hemofiltration function

technical field

The invention belongs to the technical field of medical devices, and in particular relates to a hemodialysis filtration device with hemofiltration function.

Background technique

Hemodialysis (HD) is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body, and passes through a dialyzer composed of countless hollow fibers. The whole process of exchanging substances with the principle of convection, removing metabolic waste in the body, maintaining electrolyte and acid-base balance; at the same time removing excess water in the body, and returning the purified blood is called hemodialysis.

Hemofiltration (HF) means that instead of using dialysate in the process of blood purification, a certain amount of replacement fluid is continuously added to the vascular access, fully mixed with blood, and then ultrafiltered at the same speed to achieve the removal of blood from the body. The purpose of excess water and toxins. Compared with hemodialysis, hemofiltration has the advantages of less impact on hemodynamics and higher clearance of middle molecular substances.

Hemodiafiltration (HDF) combines the advantages of hemodialysis (HD) and hemofiltration (HF), that is, the efficient removal of small molecular substances through diffusion and the efficient removal of middle molecular substances through convection. Ordinary HD has insufficient removal of middle-molecule toxins and can induce new toxins, causing high complications, reducing the quality of life of patients, and increasing mortality.

Some existing dialysis machines only have the function of hemodiafiltration (HDF), and no separate bypass system is designed. The principle of this type of dialysis machine 100 is shown in FIG. The present invention is improved based on the existing dialysis machine of this type, and has the function of hemofiltration (HF) through a simple external bypass system.

Contents of the invention

In order to solve the above-mentioned problems in the prior art, the purpose of the present invention is to provide a hemodiafiltration device with hemofiltration function.

The technical scheme adopted in the present invention is:

A hemodiafiltration device with hemofiltration function, comprising a dialyzer, a blood collection tube, a blood return line, a dialysate line, a replacement fluid line, a waste liquid line, and a tee joint;

The blood collection line and return line are both connected to the dialyzer, and the replacement fluid line is connected to the blood collection line;

The dialyzer is equipped with a dialysate inlet and a waste liquid outlet;

The waste liquid pipeline is connected with a waste liquid inlet, and the waste liquid inlet matches the waste liquid outlet;

The dialysate pipeline is connected with a dialysate outlet, and the dialysate outlet matches the dialysate inlet;

The three-way joint includes a first joint, a second joint and a third joint, the first joint matches the dialysate outlet, the second joint matches the waste liquid outlet, and the third joint matches the waste liquid inlet.

Preferably, a one-way valve is provided on the pipeline connected to the third joint on the three-way joint.

Preferably, the other end of the dialysate pipeline opposite to the dialysate outlet is connected to the source, and the inlet end of the replacement fluid pipeline is connected to the dialysate pipeline.

Preferably, an endotoxin filter is provided on the dialysate pipeline, and the endotoxin filter is located upstream of the connection between the replacement fluid pipeline and the dialysate pipeline.

Preferably, an endotoxin filter is provided on the replacement fluid pipeline.

Preferably, the other end of the waste liquid pipeline opposite to the waste liquid inlet is connected to a drain, and both the drain and the source are connected to the balance chamber of the dialysis machine.

Preferably, the blood collection tube is provided with a replacement fluid inlet, the replacement fluid pipeline is connected with a replacement fluid outlet, and the replacement fluid outlet is detachably connected to the replacement fluid inlet.

Preferably, a valve is provided at the inlet of the replacement fluid.

Preferably, a peristaltic pump is provided on the dialysate pipeline, the replacement fluid pipeline and the waste fluid pipeline.

Preferably, flow meters are provided on the dialysate pipeline, the replacement fluid pipeline and the waste fluid pipeline.

The beneficial effects of the present invention are:

The hemodiafiltration device provided by the present invention, on the basis of conventional hemodiafiltration function, only bypasses the external pipeline without changing the working mode of the dialysis machine. , can guarantee balance and normal operation.

Description of drawings

Fig. 1 is a schematic diagram of the hemodiafiltration state of the hemodiafiltration device of the present invention.

Fig. 2 is a schematic diagram of the hemofiltration state of the hemodiafiltration device in Example 1 of the present invention.

Fig. 3 is a schematic diagram of the hemofiltration state of the hemodiafiltration device in Example 2 of the present invention.

In the figure: 1-dialyzer; 11-blood inlet; 12-return blood outlet; 13-dialysis fluid inlet; 14-waste fluid outlet; 2-blood collection tube; 21-replacement fluid inlet; 22-valve; 4-dialysis fluid pipeline; 41-dialysis fluid outlet; 42-source; 5-replacement fluid pipeline; 51-replacement fluid outlet; 6-waste fluid pipeline; 61-waste fluid inlet; 62-outlet; 7-tee joint; 71-first joint; 72-second joint; 73-third joint; 74-one-way valve; 100-dialysis machine; 200-balance chamber; 300-peristaltic pump; 400-flow meter; 500 - endotoxin filter.

Detailed ways

The present invention will be further explained below in conjunction with the accompanying drawings and specific embodiments.

Example 1:

As shown in Figures 1 and 2, this embodiment provides a hemodiafiltration device with hemofiltration function, including a dialyzer 1, a blood collection tube circuit 2, a blood return circuit 3, a dialysate circuit 4, a replacement fluid Pipeline 5, waste liquid pipe 6 and tee joint 7.

The dialyzer 1 is provided with a blood inlet 11 , a blood return outlet 12 , a waste liquid outlet 14 and a dialysate inlet 13 . The dialyzer 1 is usually provided with many semi-permeable membranes in the form of hollow fibers, through which the substances to be removed from the blood are transferred into the dialysate, and the substances to be removed are drawn away through the dialysate. At the same time, excess fluid volumes can be ultrafiltered from the blood by means of the pressure gradient and removed by the dialysate flowing away. Finally, the opposite diffusion gradient, such as sodium ions, can also be used to transfer substances from the dialysate into the blood.

Both the blood collection line 2 and the blood return line 3 are connected to the dialyzer 1 , specifically, the blood collection line 2 is detachably connected to the blood inlet 11 , and the return line 3 is detachably connected to the blood return outlet 12 .

One end of the dialysate pipeline 4 is connected to the dialysate outlet 41 , and the other end is connected to the source 42 , and the dialysate outlet 41 matches the dialysate inlet 13 .

One end of the replacement fluid pipeline 5 is connected to the blood collection tube 2 . Specifically, the blood collection tube 2 is provided with a replacement fluid inlet 21 , and a valve 22 is provided at the replacement fluid inlet 21 . The replacement fluid pipeline 5 is connected with a replacement fluid outlet 51 , and the replacement fluid outlet 51 is detachably connected to the replacement fluid inlet 21 .

The other end of the replacement fluid pipeline 5 communicates with the dialysate pipeline 4 , and the replacement fluid pipeline 5 is provided with an endotoxin filter 500 .

The reverse osmosis water filtered by the dialysis machine is mixed with the concentrates of A and B liquids to become dialysate, which enters the dialysate pipeline 4 from the source 42, part of which directly enters the dialyzer 1, and the other part enters the replacement fluid pipeline 5, and passes through two series-connected The endotoxin filter 500 makes the endotoxin bacteria more up to standard and enters the blood collection tube 2 as a replacement fluid.

One end of the waste liquid pipeline 6 is connected to a waste liquid inlet 61 , and the waste liquid inlet 61 is matched with the waste liquid outlet 14 . The other end of the waste liquid pipeline 6 is connected to the drain 62 .

Both the drain port 62 and the source 42 are connected to the balance chamber 200 of the dialysis machine, the source 42 is used to receive dialysate, and the drain port 62 is used to receive waste liquid.

The tee joint 7 includes a first joint 71, a second joint 72 and a third joint 73. The first joint 71 matches the dialysate outlet 41, the second joint 72 matches the waste liquid outlet 14, and the third joint 73 matches the waste liquid inlet. 61 matches.

The above-mentioned components that are matched to each other and components that are detachably connected are correspondingly complementary, and are usually matched or detachably connected to each other in the form of a coupler.

The dialysate pipeline 4 , the replacement fluid pipeline 5 and the waste fluid pipeline 6 are provided with a peristaltic pump 300 , which is used for circulating fluid and controlling fluid discharge during dialysis treatment.

The dialysate pipeline 4 , the replacement fluid pipeline 5 and the waste fluid pipeline 6 are all provided with a flow meter 400 so that the system can monitor the volume of liquid flowing through the pipelines and achieve balance.

The hemodiafiltration device in this embodiment has a hemodiafiltration function and a hemofiltration function. As shown in Figure 1, when the hemodiafiltration device performs hemodiafiltration, the replacement fluid outlet 51 is communicated with the replacement fluid inlet 21, the waste fluid inlet 61 is communicated with the waste fluid outlet 14, and the dialysate outlet 41 is connected with the dialysate outlet. The inlet 13 is connected, and the peristaltic pump 300 and valve 22 are turned on. The replacement fluid connected from the replacement fluid pipeline 5 first enters the blood collection tube 2 and mixes with blood before entering the dialyzer 1. At the same time, the dialysis fluid connected from the dialysate pipeline 4 The liquid enters the dialyzer 1 for hemodiafiltration, and finally the waste liquid after hemodiafiltration is discharged through the waste liquid pipeline 6 . Wherein the volume A of the replacement fluid introduced from the replacement fluid pipeline 5 plus the volume B of the dialysate introduced from the dialysate pipeline 4 is equal to the volume C of the waste liquid discharged from the waste fluid pipeline 6 , so as to achieve balance.

As shown in Figure 2, when the hemodiafiltration device performs hemofiltration, the replacement fluid outlet 51 is communicated with the replacement fluid inlet 21, the first joint 71 is communicated with the dialysate outlet 41, and the second joint 72 is communicated with the waste liquid outlet. 14, connect the third joint 73 with the waste liquid inlet 61, open the peristaltic pump 300 and the valve 22, and the replacement fluid connected from the replacement fluid pipeline 5 first enters the blood collection tube 2 to mix with the blood and then enters the dialyzer 1 for further processing. During hemofiltration, the dialysate connected from the dialysate line 4 enters the three-way joint 7, and the waste liquid after hemofiltration also enters the three-way joint 7, and finally the dialysate and waste liquid enter the waste liquid line 6 to be discharged. The volume A of the replacement fluid introduced from the replacement fluid pipeline 5 plus the volume B of the dialysate introduced from the dialysate pipeline 4 is equal to the volume C of the waste fluid discharged from the waste fluid pipeline 6 . After only bypassing the external pipeline, there is no need to change the working mode of the dialysis machine 100, the balance can still be ensured, and the system can run normally.

In order to prevent pollution caused by backflow of waste liquid in the waste liquid pipeline 6 , a one-way valve 74 is provided on the pipeline connected to the third joint 73 on the three-way joint 7 .

Example 2

As shown in Figure 3, this embodiment provides a hemodiafiltration device with hemofiltration function, which differs from the hemodiafiltration device in Embodiment 1 only in that the endotoxin filter 500 is arranged in the dialysate On the pipeline 4 , the endotoxin filter 500 is located upstream of the connection between the replacement fluid pipeline 5 and the dialysate pipeline 4 .

The reverse osmosis water filtered by the dialysis machine is mixed with the concentrates of liquids A and B to become dialysate, which comes out from the source 42 and passes through two endotoxin filters 500 in series to make the endotoxin bacteria more up to standard, and part of it passes through the dialysate pipeline 4 It directly enters the dialyzer 1, and the other part enters the replacement fluid pipeline 5 to become the replacement fluid.

The present invention is not limited to the above optional embodiments, and anyone can obtain other various forms of products under the enlightenment of the present invention. The above specific implementation methods should not be construed as limiting the protection scope of the present invention. The protection scope of the present invention should be defined in the claims, and the description can be used to interpret the claims.

Claims (10)

1. a kind of filtering device for blood dialysis with blood filtering function, it is characterised in that：Including dialyzer (1), heparin tube Road (2), blood back pipeline (3), dialysis liquid pipeline (4), displacement liquid pipeline (5), waste-solution line (6) and three-way connection (7)；

Blood sampling pipe (2) and blood back pipeline (3) are connected with dialyzer (1), and displacement liquid pipeline (5) is connected with blood sampling pipe (2)；

Dialyzer (1) is equipped with dialyzate entrance (13) and waste liquid outlet (14)；

Waste-solution line (6) is connected with waste liquid entrance (61), and waste liquid entrance (61) is matched with waste liquid outlet (14)；

Dialysis liquid pipeline (4) is connected with dialyzate outlet (41), and dialyzate outlet (41) is matched with dialyzate entrance (13)；

Three-way connection (7) includes the first connector (71), the second connector (72) and third connector (73), the first connector (71) and dialysis Liquid exports (41) matching, and the second connector (72) is matched with waste liquid outlet (14), and third connector (73) is matched with waste liquid entrance (61).

2. filtering device for blood dialysis according to claim 1, it is characterised in that：Third connects on the three-way connection (7) The pipeline that head (73) is connected is equipped with check valve (74).

3. filtering device for blood dialysis according to claim 1 or 2, it is characterised in that：The dialysis liquid pipeline (4) is opposite Dialyzate exports other end connection source (42) of (41), the arrival end connection dialysis liquid pipeline (4) of displacement liquid pipeline (5).

4. filtering device for blood dialysis according to claim 3, it is characterised in that：The dialysis liquid pipeline (4) is equipped with Endotoxin filter (500), endotoxin filter (500) are located at displacement liquid pipeline (5) and the upper of liquid pipeline (4) junction of dialysing Trip.

5. filtering device for blood dialysis according to claim 3, it is characterised in that：The displacement liquid pipeline (5) is equipped with Endotoxin filter (500).

6. filtering device for blood dialysis according to claim 3, it is characterised in that：The waste-solution line (6) is with respect to waste liquid Other end connection row's mouth (62) of entrance (61), row's mouth (62) and source (42) are connected with the counter balance pocket of dialysis machine (200).

7. filtering device for blood dialysis according to claim 1, it is characterised in that：The blood sampling pipe (2) is equipped with and sets Liquid entrance (21) is changed, displacement liquid pipeline (5) is connected with displacement liquid outlet (51), and displacement liquid exports (51) and displacement liquid entrance (21) it is detachably connected.

8. filtering device for blood dialysis according to claim 7, it is characterised in that：It is equipped at the displacement liquid entrance (21) Valve (22).

9. filtering device for blood dialysis according to claim 1, it is characterised in that：The dialysis liquid pipeline (4), displacement liquid It is equipped with peristaltic pump (300) on pipeline (5) and waste-solution line (6).

10. the filtering device for blood dialysis according to claim 1 or 9, it is characterised in that：The dialysis liquid pipeline (4) is set It changes on liquid pipeline (5) and waste-solution line (6) and is equipped with flowmeter (400).