CN106730088A - A kind of two-chamber for blood purification balances liquid-supplying system with liquid - Google Patents
A kind of two-chamber for blood purification balances liquid-supplying system with liquid Download PDFInfo
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- CN106730088A CN106730088A CN201611141840.5A CN201611141840A CN106730088A CN 106730088 A CN106730088 A CN 106730088A CN 201611141840 A CN201611141840 A CN 201611141840A CN 106730088 A CN106730088 A CN 106730088A
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- 239000007788 liquid Substances 0.000 title claims abstract description 197
- 239000008280 blood Substances 0.000 title claims abstract description 129
- 210000004369 blood Anatomy 0.000 title claims abstract description 129
- 238000000746 purification Methods 0.000 title claims abstract description 18
- 238000006073 displacement reaction Methods 0.000 claims abstract description 74
- 239000002699 waste material Substances 0.000 claims abstract description 35
- 210000003462 vein Anatomy 0.000 claims abstract description 11
- 210000001367 artery Anatomy 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 238000001223 reverse osmosis Methods 0.000 claims description 14
- 239000003146 anticoagulant agent Substances 0.000 claims description 9
- 229940127219 anticoagulant drug Drugs 0.000 claims description 9
- 238000002347 injection Methods 0.000 claims description 8
- 239000007924 injection Substances 0.000 claims description 8
- 238000004891 communication Methods 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 7
- 238000001514 detection method Methods 0.000 claims description 5
- 239000011229 interlayer Substances 0.000 claims description 4
- 230000008676 import Effects 0.000 claims description 3
- 238000012806 monitoring device Methods 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 238000000108 ultra-filtration Methods 0.000 description 11
- 238000002360 preparation method Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 239000003053 toxin Substances 0.000 description 4
- 231100000765 toxin Toxicity 0.000 description 4
- 108700012359 toxins Proteins 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000001631 haemodialysis Methods 0.000 description 3
- 230000003204 osmotic effect Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 238000011085 pressure filtration Methods 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 206010028813 Nausea Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000002615 hemofiltration Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D1/00—Pipe-line systems
- F17D1/08—Pipe-line systems for liquids or viscous products
- F17D1/14—Conveying liquids or viscous products by pumping
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D3/00—Arrangements for supervising or controlling working operations
- F17D3/01—Arrangements for supervising or controlling working operations for controlling, signalling, or supervising the conveyance of a product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Mechanical Engineering (AREA)
- Water Supply & Treatment (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a kind of two-chamber for blood purification liquid-supplying system is balanced with liquid, including blood circuit, blood filter, displacement liquid loop, dialyzate supply switching circuit and waste liquid discharge loop, the artery of outlet and human body that the first entrance of the blood filter supplies switching circuit by blood circuit and dialyzate is connected, and the first outlet of blood filter is connected by blood circuit with the vein of human body；The second entrance of the blood filter supplies the outlet of switching circuit and displacement liquid loop by dialyzate, and the second outlet of blood filter supplies switching circuit by dialyzate and waste liquid is discharged loop and discharged；The dialyzate supply switching circuit includes at least two-way supply loop, and each road supply loop is alternately connected or closed with the second entrance of blood filter, and each road supply loop is alternately connected or closed with the second outlet of blood filter, forms switching structure without interruption.The present invention have automatically adjust, control accuracy is high, beneficial effect easy to use and reliable and stable.
Description
Technical field
The present invention relates to blood purification technology field, refer in particular to a kind of two-chamber for blood purification and balance feed flow with liquid
System.
Background technology
Blood cleaning equipment is by a kind of allowing, in the hollowfibre semi-permeable membrance that passes through of small-molecule substance by blood
Center portion point, allows the isotonic liquid (such as dialyzate, displacement liquid, peritoneal dialysis liquid, equilibrium liquid) of preparation, by the outer of hollow-fibre membrane
Side, in the presence of the osmotic pressure and transmembrane pressure by the principles such as Mass, convection current and ultrafiltration remove large quantity of moisture in patient body and in,
Small molecule toxins, maintain internal water, electrolyte and alkali acid balance, to reach the therapeutic system of blood purification.Current blood is net
Change equipment is divided into hemodialysis apparatus (being divided into haemodialysis control unit and hemodialysis filter again) and continuation blood cleaning equipment
(CRRT machines).
The isotonic liquid of conventional blood cleaning equipment is prepared and had the disadvantage that at present：1) isotonic liquid need to be by computer
System can be only achieved accurately with liquid in the rotation of fixed ratio rotating speed control A liquid pumps, B liquid pumps and reverse osmosis water liquid pump.If three
The rotating speed of individual liquid pump slightly little deviation or asynchronous, will cause the strength of fluid of preparation that very big skew, serious shadow occur
Ring treatment effect, or even patient life security.And because this preparation can only take fixed flow velocity to be matched, nothing
Method accomplishes the speed and flow of linear regulation preparation；2) electronic equilibrium must be claimed and by all displacements when doing Hemofiltration for Treatment
The liquid for going out is contained at one side of title, and clean displacement liquid bag hangs over the another side of title, to balance turnover liquid measure, palpus during blood filter
Liquid bag is changed in shutdown, influences treatment time, and this process manually to operate, and operation is loaded down with trivial details and easily causes operational error；3) it is necessary
Using two electronic scales, a title displacement liquid weight, another claims to displace the weight of waste liquid, and computer passes through gravity and pressure
Force snesor balance electronic scale, therefore two electronic scales must imitate periodically just, otherwise influence therapeutic effect；4) device structure is multiple
Miscellaneous, parts are more, are easily out of order, and maintenance and detection difficult, and reliability and stability are poor.
The content of the invention
It is an object of the invention to solve above-mentioned shortcoming, there is provided one kind is automatically adjusted, control accuracy is high, use scope
Extensively, easy to use, low cost and the reliable and stable two-chamber for blood purification balance liquid-supplying system with liquid.
The purpose of the present invention can be reached using following technical scheme：
A kind of two-chamber for blood purification balances liquid-supplying system with liquid, including blood circuit, blood filter, displacement liquid are returned
Road, dialyzate supply switching circuit and waste liquid discharge loop, the first entrance of the blood filter pass through blood circuit and dialyzate
The outlet of switching circuit and the artery connection of human body are supplied, the first outlet of the blood filter connected with the entrance is returned by blood
Road connects with the vein of human body；The second entrance of the blood filter supplies going out for switching circuit and displacement liquid loop by dialyzate
Mouth connection, the second outlet of the blood filter connected with the entrance supplies switching circuit by dialyzate and waste liquid discharge loop is outside
Discharge；Dialyzate supply switching circuit includes at least two-way supply loop, and each road supply loop is alternately with the of blood filter
Two entrances are connected or closed, and each road supply loop is alternately connected or closed with the second outlet of blood filter, forms switching continuous
Supply Structure.
Further, the supply loop includes cylinder body and magnetic valve, the cylinder interior be provided with elastic interlayer and by cylinder
Body is divided into closed the first cavity and the second cavity, and inlet and outlet is all provided with the first cavity and the second cavity；Described
The import of one cavity passes through the outlet of magnetic valve and the displacement liquid loop, and the outlet of first cavity passes through magnetic valve
Second entrance with the blood filter is connected；The entrance of second cavity passes through the second outlet of magnetic valve and the blood filter
Connection, the outlet of second cavity is in communication with the outside by magnetic valve.
Further, the outlet of dialyzate supply switching circuit entering by ultrafiltrate pump and net filter and blood circuit
Mouth connection is simultaneously connected with the first entrance of the blood filter.
Further, the waste liquid discharge loop includes waste drains pump and the first check valve, and the entrance of the waste drains pump passes through
First check valve is connected with the second outlet of the blood filter, and the outlet of the waste drains pump is in communication with the outside.
Further, the displacement liquid loop includes the first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump, described
The entrance of the first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump connects corresponding single liquid, first liquid respectively
The outlet of pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump is connected with the entrance of first cavity.
Further, the blood circuit includes first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second
Pressure monitor, blender, the 3rd pressure monitor, leve monitor and bubble choked flow folder, the artery of human body pass sequentially through institute
State the first of first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, blender and blood filter
Entrance is connected, and it is gentle that the first outlet of the blood filter connected with the entrance passes sequentially through the 3rd pressure monitor, leve monitor
Bubble choked flow folder is connected with the vein of human body.
Further, it is serially connected with the outlet of second cavity for preventing liquid from flowing back to the second single of the second cavity
To valve.
Further, the cylinder body is provided with the temperature control system for fluid temperature in master cylinder body.
Further, the outlet of the dialyzate supply switching circuit is provided with temperature and conductive detection device.
Implement the present invention, have the advantages that：
1st, the present invention uses multichannel supply loop alternately for blood filter supplies dialyzate/displacement liquid, and operationally, one kind is supplied
When answering loop for blood filter supply dialyzate/displacement liquid feed flow, the road supply loop is not connected with displacement liquid loop.Now, separately
Supply loop and displacement liquid circuit communication, make displacement liquid loop start to prepare dialyzate/displacement liquid and flow into supply loop all the way
In stored, when the dialyzate/displacement liquid in other supply loops has been used up, can switch in time and alternately for blood filter enters
Row feed flow, whole process changes liquid without shutting down, it is ensured that energy dialyzate/displacement liquid without interruption so that fluid flow and pressure are steady
Fixed, stable and reliable in work, the blood pressure stabilization of patient during treatment dramatically reduces headache, Nausea and vomiting, extremely effective improves
The effect for the treatment of.
2nd, supply loop of the present invention using the dialyzate/displacement liquid feed flow of reserve type Supply Structure, the dialyzate of supply/
The concentration of displacement liquid, temperature and osmotic pressure will not be influenceed by flow rate of liquid speed, be capable of achieving dialyzate/displacement flow velocity
It is linear adjustable, it is easy to use and reliable and stable with the need for meeting flow rate of liquid speed is adjusted in treatment at any time.Solve existing
There are the need produced by displacement liquid loop is directly supplied to control A liquid pumps, B liquid in fixed ratio rotating speed by computer system
The rotation of pump and reverse osmosis water liquid pump, can be only achieved accurately with liquid, and if three rotating speeds of liquid pump slightly little deviation or not
It is synchronous, will cause the strength of fluid of preparation that very big skew occurs, the effect for the treatment of is had a strong impact on, or even the life of patient is pacified
Full problem.
3rd, the present invention can adjust the dialyzate/displacement liquid mixed with blood in inflow blood circuit by adjusting ultrafiltrate pump
Amount realize the control to ultrasiltrated rate, ultrafiltration pressure and ultrafiltration volume etc., meeting to the requirement in treatment to ultrafiltration parameter,
With versatility it is good and easy to use the characteristics of.
4th, the present invention installs waste drains pump to realize to waste liquid and dialyzate/displacement liquid stream at the second outlet of blood filter
The control of amount, without using gravity and pressure sensor and electronic equilibrium weighing device, greatly simplifies the structure of equipment, and behaviour
Make simple, work more security reliability.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
The accompanying drawing to be used needed for having technology description is briefly described, it should be apparent that, drawings in the following description are only this
Some embodiments of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can be with
Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is the structural representation that the present invention balances liquid-supplying system for the two-chamber of blood purification with liquid.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made
Embodiment, belongs to the scope of protection of the invention.
Embodiment
Reference picture 1, the present embodiment is related to liquid-supplying system, including blood circuit 1, blood filter 2, displacement liquid loop 3, dialyzate
Supply switching circuit 4 and waste liquid discharge loop 5, the first entrance 21 of the blood filter 2 are supplied by blood circuit 1 with dialyzate
The outlet of switching circuit 4 and the artery connection of human body, the first outlet 22 of the blood filter 2 connected with the entrance are returned by blood
Road 1 connects with the vein of human body；The second entrance 23 of the blood filter 2 is supplied switching circuit 4 and is returned with displacement liquid by dialyzate
The outlet on road 3, the second outlet 24 of the blood filter 2 connected with the entrance supplies switching circuit 4 and waste liquid by dialyzate
Discharge loop 5 discharges；The dialyzate supply switching circuit 4 includes at least two-way supply loop 41, each road supply loop
41 alternately connect or close with the second entrance 23 of blood filter 2, and each road supply loop 41 replaces the second outlet with blood filter 2
24 connections are closed, and form switching structure without interruption.
The structure uses multichannel supply loop 41 alternately for blood filter 2 supplies dialyzate/displacement liquid, operationally, a kind of
When supply loop 41 is that blood filter 2 supplies dialyzate/displacement liquid feed flow, the road supply loop 41 is not connected with displacement liquid loop 3.
Now, another road supply loop 41 is connected with displacement liquid loop 3, makes displacement liquid loop 3 start to prepare dialyzate/displacement liquid cocurrent
To enter stored in supply loop 41, when the dialyzate/displacement liquid in other supply loops 41 has been used up, can switch in time and
Alternately for blood filter 2 carries out feed flow, whole process changes liquid without shutting down, it is ensured that energy dialyzate/displacement liquid without interruption so that liquid
Body flow and pressure stability, stable and reliable in work, the blood pressure stabilization of patient during treatment dramatically reduce headache, nausea, vomit
Tell, extremely effective improve the effect for the treatment of.
Because the supply loop 41 is using the Supply Structure of the dialyzate/displacement liquid feed flow of reserve type, the dialyzate of supply/
The concentration of displacement liquid, temperature and osmotic pressure will not be influenceed by flow rate of liquid speed, be capable of achieving dialyzate/displacement flow velocity
It is linear adjustable, it is easy to use and reliable and stable with the need for meeting flow rate of liquid speed is adjusted in treatment at any time.Solve existing
There are the need produced by displacement liquid loop 3 is directly supplied to control A liquid pumps, B in fixed ratio rotating speed by computer system
The rotation of liquid pump and reverse osmosis water liquid pump, can be only achieved accurately with liquid, and if three rotating speeds of liquid pump slightly little deviation or
It is asynchronous, will cause the strength of fluid of preparation that very big skew occurs, have a strong impact on the effect for the treatment of, in addition patient life
The problem of safety.
The supply loop 41 includes cylinder body 411 and magnetic valve 412, be provided with elastic interlayer inside the cylinder body 411 and incite somebody to action
Cylinder body 411 is divided into closed the first cavity 413 and the second cavity 414, is all provided with the first cavity 413 and the second cavity 414
Inlet and outlet；The import of first cavity 413 passes through the outlet of magnetic valve 412 and the displacement liquid loop 3, described
The outlet of the first cavity 413 is connected by magnetic valve 412 with the second entrance 23 of the blood filter 2；Second cavity 414
Entrance is connected by magnetic valve 412 with the second outlet 24 of the blood filter 2, and the outlet of second cavity 414 passes through electromagnetism
Valve 412 is in communication with the outside.
First cavity 413 is used to store the dialyzate/displacement liquid of concentration needed for the proportioning of displacement liquid loop 3 is completed, the second chamber
Body 414 is used to store the waste liquid flowed out from the second outlet 24 of blood filter 2.Prepared in the first cavity 413 in displacement liquid loop 3
During dialyzate/displacement liquid, the liquid in the first cavity 413 is squeezed by elastic interlayer to the spatial spread in the second cavity 414
The waste liquid in the second cavity 414 is pressed, so as to play a part of that the waste liquid in the second cavity 414 is cleared up in advance.And
During one cavity 413 is to the supply dialyzate/displacement liquid of blood filter 2, constantly second is flowed back to from the second outlet 24 of blood filter 2
Waste liquid in cavity 414 extrudes the dialyzate/displacement liquid in the first cavity 413 to the spatial spread in the first cavity 413, carries
Dialyzate/displacement liquid is set stably to be flowed for extruding force, simple structure reduces the use of liquid pump and other auxiliary components
Amount, low cost of manufacture and can reduce fault rate.
The outlet of the dialyzate supply switching circuit 4 is connected by ultrafiltrate pump 6 and net filter 7 with the entrance of blood circuit 1
Lead to and connected with the first entrance 21 of the blood filter 2.By adjust ultrafiltrate pump 6 can adjust inflow blood circuit 1 in blood
The amount of the dialyzate/displacement liquid of liquid mixing realizes the control to ultrasiltrated rate, ultrafiltration pressure and ultrafiltration volume etc., to meet to controlling
To the requirement of ultrafiltration parameter in treatment, with versatility it is good and easy to use the characteristics of.Returned by the adjustable blood that enters of ultrafiltrate pump 6
The flow speed scope of the dialyzate/displacement liquid in road 1 is 50-500ml/ minute, be conducive to making preposition displacement liquid blood filter or after
Put the selection of the methods such as displacement liquid blood filter.
Waste liquid discharge loop 5 includes the check valve 52 of waste drains pump 51 and first, and the entrance of the waste drains pump 51 is by the
One check valve 52 is connected with the second outlet 24 of the blood filter 2, and the outlet of the waste drains pump 51 is in communication with the outside.In blood filter
Waste drains pump 51 is installed at 2 second outlet 24 to realize the control to waste liquid and dialyzate/displacement flow quantity, without using weight
Power and pressure sensor and electronic equilibrium weighing device, greatly simplifie the structure of equipment, and simple to operate, work safer
Reliability.Flow speed scope by the adjustable waste liquid for pumping out the external world of waste drains pump 51 is 0-2000ml/ hours, the ultrafiltration
The flow speed of the waste liquid for going out is adjustable at any time, is easy to Clinical practice, and the liquid that ultrafiltration goes out loads with graduated ultrafiltrate vessel
In, how much the amount of liquid that ultrafiltration goes out can in real time know that the liquid measure that ultrafiltration goes out should be the dehydrating amount of patient.
The displacement liquid loop 3 includes the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34, described
The entrance of the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34 connects corresponding single liquid respectively, described
The outlet of the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34 connects with the entrance of first cavity 413
It is logical.Control system controls the rotating speed ratio of the first liquid pump 31, the second liquid pump 32, the 3rd liquid pump 33 and reverse osmosis water pump 34, and A is made respectively
Liquid, B liquid, S liquid are mixed by firm discharge with reverse osmosis water and are matched into required concentration.
The blood circuit 1 includes that first pressure monitor 11, the 4th liquid pump 12, anti-coagulants injection device 13, second are pressed
Power monitor 14, blender 15, the 3rd pressure monitor 16, leve monitor 17 and bubble choked flow folder 18, the artery of human body according to
It is secondary by the first pressure monitor 11, the 4th liquid pump 12, anti-coagulants injection device 13, second pressure monitor 14, mixing
Device 15 is connected with the first entrance 21 of blood filter 2, and the first outlet 22 of the blood filter 2 connected with the entrance passes sequentially through the 3rd pressure
Power monitor 16, leve monitor 17 and bubble choked flow folder 18 is connected with the vein of human body.
The artery of patient by arterial puncture needle successively with the first pressure monitor 11, the 4th liquid pump 12, anti-coagulants
Injection device 13, second pressure monitor 14 and blender 15 are connected with the first entrance 21 of blood filter 2；Blood flows into artery and wears
After pricker, after injecting anti-coagulants through anti-coagulants injection device 13, it is input into blender 15 by the 4th liquid pump 12.In blender 15
Middle blood is conveyed into blood filter 2 after mixing with dialyzate/displacement liquid by the first entrance 21 of blood filter 2.Wherein contain toxin
Dialyzate/displacement liquid be filtered out, clean blood is exported from the first outlet 22 of blood filter 2, by passing sequentially through the 3rd pressure
Power monitor 16, leve monitor 17 and bubble choked flow folder 18 is connected with the vein of human body and flows to the vein of human body, so that
Defeated time in patient body.
Enter the second cavity 414 to prevent the waste liquid adverse current of discharge line, gone here and there in the outlet of second cavity 414
It is connected to for preventing liquid from flowing back the second check valve 8 to the second cavity 414.
In order to ensure that the mixed temperature value of the dialyzate/displacement liquid for flowing into the second entrance 23 of blood filter 2 reaches requirement and constant temperature,
The cylinder body 411 is provided with the temperature control system for controlling fluid temperature in cylinder body 411.
The outlet of the dialyzate supply switching circuit 4 is provided with temperature and conductive detection device 9.By temperature and conductance
Detection means 9 can in real time be examined to the temperature and concentration that enter the dialyzate/displacement liquid of the second entrance 23 of blood filter 2
Survey, and the data that will be detected are sent to control system in real time, such as temperature or concentration does not reach standard, then control system control phase
The magnetic valve 412 answered is closed, and the dialyzate/displacement liquid in the first cavity 413 is flowed into the second entrance 23 of blood filter 2,
The problem for requiring even malpractice is not reached so as to prevent therapeutic effect.
Operation principle of the invention：
The blood of patient is connected to the entrance of the 4th liquid pump 12 by arterial puncture needle, is input into mixing by the 4th liquid pump 12
In device 15.First entrance 21 after blood mixes with dialyzate/displacement liquid in the blender 15 by blood filter 2 is conveyed into blood
Filter 2.Wherein dialyzate/the displacement liquid containing toxin is filtered out, and clean blood is exported from the first outlet 22 of blood filter 2, warp
Cross and pass sequentially through the 3rd pressure monitor 16, leve monitor 17 and bubble choked flow folder and 18 connected with the vein of human body and flow to people
In the vein of body, thus defeated time in patient body.
Dialyzate/displacement liquid through putting the extraction of ultrafiltrate pump 6 flows through net filter 7 and is input in blender 15, in blender 15
Middle blood is transported to blood filter 2 after mixing with dialyzate/displacement liquid by the first entrance 21 of blood filter 2, the dialysis containing toxin
The second outlet 24 that liquid/displacement liquid turns into waste liquid and passes through blood filter 2 is drawn in the second cavity 414, is installed on blood filter 2
Second outlet 24 pipeline on waste drains pump 51 extract liquid out can be loaded in ultrafiltrate vessel or being connected on sewer pipe directly
Exclude, dehydrating amount when this liquid is the filter treatment of patient's blood.
During the supply dialyzate/displacement liquid of second entrance 23 for blood filter 2, first by the first supply loop 41
In the first cavity 413 of cylinder body 411 supplied, meanwhile, displacement liquid loop 3 prepares dialyzate/displacement liquid and flows into second
In the cylinder of supply loop 41.When the dialyzate/displacement liquid in the first cavity 413 runs out, the cylinder body of the second supply loop 41
The magnetic valve 412 of the outlet of 411 the first cavity 413 is opened, so that tangentially to the second supply loop 41 for blood filter 2 is supplied
Analysis liquid/displacement liquid.The magnetic valve 412 of the outlet of the first cavity 413 of the cylinder body 411 of the first supply loop 41 is closed simultaneously, and
And the magnetic valve 412 of its entrance is opened, displacement liquid loop 3 prepares dialyzate/displacement liquid and flows into the cylinder of the first supply loop 41
It is interior, so as to realize alternately being supplied for blood filter 2 purpose of dialyzate/displacement liquid.
Above disclosed is only a kind of preferred embodiment of the invention, can not limit the power of the present invention with this certainly
Sharp scope, therefore the equivalent variations made according to the claims in the present invention, still belong to the scope that the present invention is covered.
Claims (9)
1. a kind of two-chamber for blood purification balances liquid-supplying system with liquid, it is characterised in that：Including blood circuit, blood filter,
Displacement liquid loop, dialyzate supply switching circuit and waste liquid discharge loop, the first entrance of the blood filter pass through blood circuit
The artery of outlet and human body with dialyzate supply switching circuit is connected, and the first outlet of the blood filter connected with the entrance is led to
Blood circuit is crossed to be connected with the vein of human body；The second entrance of the blood filter supplies switching circuit and displacement liquid by dialyzate
The outlet in loop, the second outlet of the blood filter connected with the entrance supplies switching circuit by dialyzate and waste liquid is discharged
Loop discharges；The dialyzate supply switching circuit includes at least two-way supply loop, and each road supply loop replaces and blood
The second entrance connection of filter is closed, and each road supply loop is alternately connected or closed with the second outlet of blood filter, is formed
Switch structure without interruption.
2. a kind of two-chamber for blood purification according to claim 1 balances liquid-supplying system with liquid, it is characterised in that：Institute
Stating supply loop includes cylinder body and magnetic valve, and the cylinder interior is provided with elastic interlayer and cylinder body is divided into the first closed chamber
Inlet and outlet is all provided with body and the second cavity, the first cavity and the second cavity；The import of first cavity passes through electromagnetism
The outlet in valve and the displacement liquid loop, the outlet of first cavity is entered by magnetic valve with the second of the blood filter
Mouth connection；The entrance of second cavity is connected by magnetic valve with the second outlet of the blood filter, second cavity
Outlet is in communication with the outside by magnetic valve.
3. a kind of two-chamber for blood purification according to claim 1 balances liquid-supplying system with liquid, it is characterised in that：Institute
The outlet for stating dialyzate supply switching circuit is connected with the entrance of blood circuit by ultrafiltrate pump and net filter and filtered with the blood
The first entrance connection of device.
4. a kind of two-chamber for blood purification according to claim 1 balances liquid-supplying system with liquid, it is characterised in that：Institute
Stating waste liquid discharge loop includes waste drains pump and the first check valve, and the entrance of the waste drains pump is filtered by the first check valve with the blood
The second outlet connection of device, the outlet of the waste drains pump is in communication with the outside.
5. a kind of two-chamber for blood purification according to claim 1 balances liquid-supplying system with liquid, it is characterised in that：Institute
Displacement liquid loop is stated including the first liquid pump, the second liquid pump, the 3rd liquid pump and reverse osmosis water pump, first liquid pump, the second liquid pump, the
The entrance of three liquid pumps and reverse osmosis water pump connects corresponding single liquid respectively, first liquid pump, the second liquid pump, the 3rd liquid pump and
The outlet of reverse osmosis water pump is connected with the entrance of first cavity.
6. liquid-supplying system, its feature are balanced with liquid according to a kind of any described two-chamber for blood purification of claim 1 to 5
It is：The blood circuit includes first pressure monitor, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, mixed
Clutch, the 3rd pressure monitor, leve monitor and bubble choked flow folder, the artery of human body pass sequentially through the first pressure monitoring
Device, the 4th liquid pump, anti-coagulants injection device, second pressure monitor, blender are connected with the first entrance of blood filter, are entered with this
The first outlet of the blood filter of mouthful connection passes sequentially through the 3rd pressure monitor, leve monitor and bubble choked flow folder and human body
Vein is connected.
7. a kind of two-chamber for blood purification according to claim 2 balances liquid-supplying system with liquid, it is characterised in that：Institute
It is serially connected with the outlet for stating the second cavity for preventing liquid from flowing back the second check valve to the second cavity.
8. a kind of two-chamber for blood purification according to claim 2 balances liquid-supplying system with liquid, it is characterised in that：Institute
State cylinder body and be provided with temperature control system for fluid temperature in master cylinder body.
9. liquid-supplying system, its feature are balanced with liquid according to a kind of any described two-chamber for blood purification of claim 1 to 5
It is：The outlet of the dialyzate supply switching circuit is provided with temperature and conductive detection device.
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| CN201611141840.5A CN106730088A (en) | 2016-12-12 | 2016-12-12 | A kind of two-chamber for blood purification balances liquid-supplying system with liquid |
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| CN201611141840.5A CN106730088A (en) | 2016-12-12 | 2016-12-12 | A kind of two-chamber for blood purification balances liquid-supplying system with liquid |
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Cited By (3)
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| CN108744103A (en) * | 2018-07-11 | 2018-11-06 | 何忠贵 | A kind of filtering device for blood dialysis with blood filtering function |
| CN109663159A (en) * | 2019-01-17 | 2019-04-23 | 郑州大学第附属医院 | A kind of blood purification automatic liquid matching capacity balancing device |
| CN110741263A (en) * | 2017-06-30 | 2020-01-31 | 深圳迈瑞生物医疗电子股份有限公司 | Liquid supply device, sample analyzer and liquid supply method |
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