CN108542349B - Bimodal lens fundus imaging system - Google Patents
Bimodal lens fundus imaging system Download PDFInfo
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- CN108542349B CN108542349B CN201810497080.4A CN201810497080A CN108542349B CN 108542349 B CN108542349 B CN 108542349B CN 201810497080 A CN201810497080 A CN 201810497080A CN 108542349 B CN108542349 B CN 108542349B
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- lens group
- fundus
- blood oxygen
- beam splitter
- beams
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- 230000002902 bimodal effect Effects 0.000 title claims abstract description 21
- 238000003384 imaging method Methods 0.000 title claims abstract description 12
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 56
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 56
- 239000001301 oxygen Substances 0.000 claims abstract description 56
- 239000008280 blood Substances 0.000 claims abstract description 55
- 210000004369 blood Anatomy 0.000 claims abstract description 55
- 230000000149 penetrating effect Effects 0.000 claims abstract description 4
- 210000001525 retina Anatomy 0.000 description 7
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 208000030533 eye disease Diseases 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000003161 choroid Anatomy 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000004088 microvessel Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003733 optic disk Anatomy 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
- 238000012014 optical coherence tomography Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14555—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for the eye fundus
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Ophthalmology & Optometry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The invention discloses and provides a bimodal lens fundus imaging system which has the advantages of simple structure, small lens size, good universality and strong fundus image acquisition capability. The invention comprises a fundus beam generating unit, a relay lens group, a first beam splitter, a second beam splitter, a single-reflection lens group, a blood oxygen lens group, a second blood oxygen lens group, a single-reflection image sensor, a first blood oxygen image sensor and a second blood oxygen image sensor; the first beam splitter is positioned behind the relay lens group; the fundus beam generating unit sends out fundus beams reflected by fundus, the fundus beams reach the first beam splitter after penetrating the relay lens group, the first beam splitter splits the fundus beams into two beams of light, the two beams of light split by the first beam splitter respectively enter the single-reflection lens group and the second beam splitter, the second beam splitter splits the beams of light into two beams of light, and the two beams of light split by the second beam splitter respectively enter the first blood oxygen lens group and the second blood oxygen lens group. The invention is applied to the technical field of a bimodal lens fundus imaging system.
Description
Technical Field
The invention relates to a fundus camera, in particular to a bimodal lens fundus imaging system.
Background
Fundus refers to the bottom of the eye, i.e., the bottommost tissue of the eye. It includes retina, fundus blood vessel, optic nerve head, optic nerve fiber, macula on retina, choroid behind retina, etc. If lesions occur at these sites, they are collectively referred to as fundus diseases.
The retina is a film with a highly complex structure, a large number of capillaries are distributed on the film, and the retina is the only deep micro-vascular network which can be directly observed from non-wound in a human body. The observation of the vascular veins on the retina of the human eye can provide important basis for doctors to diagnose a plurality of eye diseases, even systemic diseases. For example, hypertension, hyperlipidemia, nephropathy, diabetes, coronary heart disease, etc., and changes in physiological state at the early stage of onset are all reflected on the fundus.
Whether diabetes, eye diseases or other cardiovascular diseases, the eye bottom is checked along with the change of the eye bottom state when the disease is developed, so that the method is an effective way for timely finding and controlling the disease. Currently, clinically effective fundus examination devices mainly have five types: ophthalmoscope, slit-lamp microscope, fundus camera, scanning laser ophthalmoscope, optical coherence tomography, etc. The five inspection modes are characterized. But comprehensively considers the maturity, the practicability, the operation difficulty and the production cost of the prior technical development, the fundus camera is still the most widely applied fundus examination equipment. However, the existing fundus examination device is complex in structure, and generally only can realize single-mode photographing, for example, only can obtain gray level images or color fundus images of fundus, and further cannot sufficiently examine fundus.
Disclosure of Invention
The invention aims to solve the technical problem of overcoming the defects of the prior art and providing a bimodal lens fundus imaging system which has the advantages of simple structure, small lens size, good universality and strong fundus image acquisition capability.
The technical scheme adopted by the invention is as follows: the invention comprises a fundus beam generating unit, a relay lens group, a first beam splitter, a second beam splitter, a single-reflecting lens group and a bimodal lens, wherein the bimodal lens comprises a first blood oxygen lens group and a second blood oxygen lens group, and a single-reflecting image sensor, a first blood oxygen image sensor and a second blood oxygen image sensor are respectively arranged behind the single-reflecting lens group, the first blood oxygen lens group and the second blood oxygen lens group; the first beam splitter is positioned behind the relay lens group; the fundus beam generating unit sends out fundus beams reflected by fundus, the fundus beams reach the first beam splitter after penetrating through the relay lens group, the first beam splitter divides the fundus beams into two beams of light, the two beams of light split by the first beam splitter enter the single-reflecting lens group and the second beam splitter respectively, the second beam splitter divides the beams of light into two beams of light again, and the two beams of light split by the second beam splitter enter the first blood oxygen lens group and the second blood oxygen lens group respectively.
Further, the light rays between the relay lens group and the single reflecting lens group are parallel light.
Further, the angle of light between the relay lens group and the single mirror group is less than 8 degrees.
Further, after the light beam passes through the first blood oxygen mirror group and the second blood oxygen mirror group, the first blood oxygen image sensor and the second blood oxygen image sensor respectively acquire fundus pictures with 570nm wavelength and fundus pictures with 610nm wavelength.
The beneficial effects of the invention are as follows: the invention adopts the design of a bimodal lens, and comprises a fundus beam generating unit, a relay lens group, a first beam splitter, a second beam splitter, a single-reflecting lens group and a bimodal lens, wherein the bimodal lens comprises a first blood oxygen lens group and a second blood oxygen lens group, and a single-reflecting image sensor, a first blood oxygen image sensor and a second blood oxygen image sensor are respectively arranged behind the single-reflecting lens group, the first blood oxygen lens group and the second blood oxygen lens group; the first beam splitter is positioned behind the relay lens group; the invention is characterized in that the fundus beam generating unit sends out fundus beams reflected by fundus, the fundus beams penetrate the relay lens group and then reach the first beam splitter, the first beam splitter divides the fundus beams into two beams of light, the two beams of light split by the first beam splitter enter the single-reflection lens group and the second beam splitter respectively, the second beam splitter divides the beams of light into two beams of light, the two beams of light split by the second beam splitter enter the first blood oxygen lens group and the second blood oxygen lens group respectively, so that the design of the bimodal lens can be well embedded into an original fundus camera, the universality is good, the lens size is small, the fundus image acquisition capability is strong, fundus color photographs can be acquired through the single-reflection image sensor, fundus images with 570nm wavelength and 610nm wavelength can be acquired through the first blood oxygen image sensor and the second blood oxygen image sensor, and the oxygen saturation of blood vessels of the fundus can be measured through combining corresponding algorithms.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Detailed Description
As shown in fig. 1, in the present embodiment, the present invention includes a fundus beam generating unit 1, a relay lens group 2, a first beam splitter 5, a second beam splitter 6, a single-mirror group 7, and a bimodal lens including a first blood oxygen mirror group 8 and a second blood oxygen mirror group 9, a single-mirror image sensor 10, a first blood oxygen image sensor 11, and a second blood oxygen image sensor 12 being provided behind the single-mirror group 7, the first blood oxygen mirror group 8, and the second blood oxygen mirror group 9, respectively; the first beam splitter 5 is located behind the relay lens group 2; the fundus beam generating unit 1 emits fundus beams reflected by fundus, the fundus beams reach the first beam splitter 5 after penetrating the relay lens group 2, the first beam splitter 5 splits the fundus beams into two beams, the two beams split by the first beam splitter 5 respectively enter the single reflecting lens group 7 and the second beam splitter 6, the second beam splitter 6 splits the beams into two beams, and the two beams split by the second beam splitter 6 respectively enter the first blood oxygen lens group 8 and the second blood oxygen lens group 9.
In this embodiment, the light rays between the relay lens group 2 and the single-reflection lens group 7 are parallel light, so that the position of the first beam splitter 5 is insensitive, and installation and placement are facilitated.
In this embodiment, the angle of light between the relay lens group 2 and the single-reflection lens group 7 is smaller than 8 degrees, which is advantageous for the splitting of the dielectric film.
In this embodiment, after the light beam passes through the first blood oxygen mirror group 8 and the second blood oxygen mirror group 9, the first blood oxygen image sensor 11 and the second blood oxygen image sensor 12 acquire a fundus image with a wavelength of 570nm and a fundus image with a wavelength of 610nm, respectively.
According to the invention, not only can fundus color illumination be obtained through the single-reflection image sensor 10, but also fundus images under 570nm wavelength and 610nm wavelength can be obtained through the first blood oxygen image sensor 11 and the second blood oxygen image sensor 12, and the blood oxygen saturation of human eye retina blood vessels can be measured through the fundus images with 570nm and 610nm wavelength and by combining corresponding algorithms.
The invention is applied to the technical field of a bimodal fundus imaging system.
While the embodiments of this invention have been described in terms of practical aspects, they are not to be construed as limiting the meaning of this invention, and modifications to the embodiments and combinations with other aspects thereof will be apparent to those skilled in the art from this description.
Claims (4)
1. A bimodal ophthalmic fundus imaging system, characterized by: the bimodal lens fundus imaging system comprises a fundus light beam generating unit (1), a relay lens group (2), a first beam splitter (5), a second beam splitter (6), a single-reflecting lens group (7) and a bimodal lens, wherein the bimodal lens comprises a first blood oxygen lens group (8) and a second blood oxygen lens group (9), and a single-reflecting image sensor (10), a first blood oxygen image sensor (11) and a second blood oxygen image sensor (12) are respectively arranged behind the single-reflecting lens group (7), the first blood oxygen lens group (8) and the second blood oxygen lens group (9); the first beam splitter (5) is positioned behind the relay lens group (2); the fundus beam generation unit (1) sends out fundus beams reflected by fundus, the fundus beams reach the first beam splitter (5) after penetrating through the relay lens group (2), the first beam splitter (5) divides the fundus beams into two beams of light, the two beams of light separated by the first beam splitter (5) respectively enter the single reflecting lens group (7) and the second beam splitter (6), the second beam splitter (6) divides the beams of light into two beams of light again, and the two beams of light separated by the second beam splitter (6) respectively enter the first blood oxygen lens group (8) and the second blood oxygen lens group (9).
2. The bimodal ophthalmic fundus imaging system according to claim 1, wherein: the light rays between the relay lens group (2) and the single-reflection lens group (7) are parallel light.
3. The bimodal ophthalmic fundus imaging system according to claim 1 or 2, wherein: the angle of light between the relay lens group (2) and the single-reflection lens group (7) is smaller than 8 degrees.
4. The bimodal ophthalmic fundus imaging system according to claim 1, wherein: after the light beam passes through the first blood oxygen mirror group (8) and the second blood oxygen mirror group (9), the first blood oxygen image sensor (11) and the second blood oxygen image sensor (12) respectively acquire fundus pictures with 570nm wavelength and fundus pictures with 610nm wavelength.
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CN201810497080.4A CN108542349B (en) | 2018-05-22 | 2018-05-22 | Bimodal lens fundus imaging system |
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CN201810497080.4A CN108542349B (en) | 2018-05-22 | 2018-05-22 | Bimodal lens fundus imaging system |
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CN208755963U (en) * | 2018-05-22 | 2019-04-19 | 合肥奥比斯科技有限公司 | Bimodal eyeglass eyeground imaging system |
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DE102013005869B4 (en) * | 2013-04-08 | 2016-08-18 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Patient management module |
CN207168484U (en) * | 2017-01-12 | 2018-04-03 | 天津工业大学 | Binocular fundus camera imaging optical system |
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