CN108524399A - A kind of lotion and preparation method thereof with long-acting moisture-keeping efficacy - Google Patents
A kind of lotion and preparation method thereof with long-acting moisture-keeping efficacy Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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Abstract
The invention discloses a kind of lotions and preparation method thereof with long-acting moisture-keeping efficacy.By mass percentage, the lotion is grouped as by the following raw material group：Long-acting moisturizing complexing agent 10 20%, solvent 55 75%, emulsifier 1 5%, moisturizing grease 5 25%, stabilizer 0.1 1.5%, pH adjusting agent 0.01 1%, skin conditioning agent 1 10%, preservative 0.1 1%, aromatic 0.03 0.5%.The lotion of the present invention, feature are that the ingredient of moisturizing combination is：Echinacea angustifolia extract, Acer negundo extract, saccharomycete/rice fermentation Product filtrate, lauroyl dilactic acid sodium, Cer NP, Cer AP II, Cer EOS, phytosphingosine, phytosterol, by optimizing the compounding and adding proportion of long-acting moisturizing complexing agent, there is the moistening effect up to 4 8h.
Description
Technical field
The present invention relates to a kind of moisturizing emulsions, belong to cosmetic technical field, and in particular to one kind having long-acting moisturizing work(
Lotion of effect and preparation method thereof.
Background technology
The content of moisture in skin, it is fine and smooth, glossy with skin, it is very crucial whether healthy.Using with moisturizing work(
The lotion of effect is that consumer keeps skin water tender, the important channel of appropriate moisturizing.The lotion of current moisturizing class on the market, category
Numerous, moistening effect is different, commonly uses polyalcohols and trehalose, glucan, the hyaluronic acids such as moisturizing ingredient such as glycerine, butanediol
Sodium etc. emulsifies gained, on the skin in conjunction with moisturizing grease such as vaseline, caprylic/capric triglyceride, isononyl isononanoate etc.
Cause is not high with Stratum corneum lipids double-layer structure compatibility, is unfavorable for the infiltration and conduction of active material so that skin cannot be permanent
Keep higher water content.
How a kind of lotion skin-protection product with long-acting moisture-keeping efficacy is developed, to meet the various demands in market,
It is that those skilled in the art are badly in need of the technical barrier solved.
Invention content
The object of the present invention is to provide a kind of lotion with long-acting moistening effect, moisturizing is combined in water, oil sources
Aspect takes into account enhancing skin barrier function, and the sebum film of cuticula high-moisture outside skin is combined to contain to skin epidermis inside
The increase of water, plays a positive role.
The present invention also provides a kind of preparation methods of the above-mentioned lotion with long-acting moistening effect.
To solve the above problems, the present invention uses following technical scheme：
A kind of lotion with long-acting moisture-keeping efficacy contains long-acting moisturizing complexing agent in the lotion, by mass percentage
Meter, the long-acting moisturizing complexing agent are made of following components：
As priority, by mass percentage, the long-acting moisturizing complexing agent is made of following components：
The lotion also contains other raw materials, including solvent, emulsifier, moisturizing grease, stabilizer, pH adjusting agent, anti-corrosion
Agent, aromatic, by mass percentage, the lotion are made of following raw material components：
Preferably, by mass percentage, the lotion is made of following raw material components：
Furthermore, the solvent of the lotion is selected from water, glycerine, butanediol, 1,3-PD, dipropylene glycol, poly- sweet
Any or their mixture in oily ether -26.
The emulsifier of the lotion is selected from cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, glycerol stearate
Ester, PEG-100 stearates, C12-20 alkyl glucosides, C20-22 alcohol phosphate, PEG-10 iso stearic acid of glycerine ester, sucrose
Laurate, Glyceryl stearate citrate, polyglycereol-3-methyl distearate or their mixture.
The moisturizing grease of the lotion is selected from saualane, glycerine three (thylhexoic acid) ester, avocado (PERSEA
GRATISSIMA) oil, octyl polymethyl siloxane, isononyl isononanoate, caprylic/capric triglyceride, Jojoba
(SIMMONDSIA CHINENSIS) seed oil, sad Propylheptyl, ring five dimethyl silicone polymer, cetanol, C10-18 resin acids
In triglyceride, dimethyl silicone polymer, Queensland nut (MACADAMIA TERNIFOLIA) seed oil it is any or they
Mixture.
The stabilizer of the lotion is selected from carbomer, xanthans, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters crosslinking
Polymer, ammonium acryloyl taurate/VP copolymer, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers,
Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, ammonium acryloyldime-thyltaurate/- 25 first of docosyl alcohol polyethers
Any or their mixture in base acrylate crosspolymers.
The pH adjusting agent of the lotion is selected from citric acid, sodium citrate, sodium hydroxide, triethanolamine, aminomethyl propanol, ammonia
Any or their mixture in butantriol.Between pH adjusting agent controlization lotion pH ranging from 5.5-6.5.
The skin conditioning agent of the lotion be selected from glycine betaine, trehalose, Sodium Hyaluronate, beta glucan, α-mannosan,
Any or their mixture in chitosan, biological carbohydrate gum -1, levulan, xylitol.
The preservative of the lotion is selected from methyl hydroxybenzoate, Nipasol, potassium sorbate, sodium benzoate, Chlorphenesin, benzene oxygen
It is any one or more in ethyl alcohol.
The aromatic of the lotion is selected from containing the few plant flowers fruity of anaphylactogen.
In addition, the present invention also provides the preparation method of the above-mentioned lotion with long-acting moisture-keeping efficacy, include the following steps：
1) the A item components of 56-76% by mass percentage, are weighed：Solvent, stabilizer, skin conditioning agent are stirred
It is even；
2) the B item components of 11-25% by mass percentage, are weighed：Emulsifier, moisturizing grease, for use；
3) the C item components of 12-18% by mass percentage, are weighed：PH conditioning agents, long-acting moisturizing complexing agent, for use；
4) the D item components of 0.25-1.15% by mass percentage, are weighed：Preservative, aromatic, for use；
5) A components are heated to 80-85 DEG C, insulated and stirred is pumped into homogenizer, homogeneous (2500rpm) 5 after 30 minutes
Minute, it stirs 5 minutes, heat preservation defoaming；
6) B components are heated to 80-85 DEG C, melt complete, addition homogenizer, homogeneous (3000rpm) 5 minutes, stirring 5
Minute, cooling；
7) 45 DEG C are cooled to, C components, D components are added, are stirred until homogeneous.
The A component：Water (To 100%), glycerine (5%), butanediol (3%), ethyl alcohol (2%), carbomer
(0.1%), xanthans (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%)；
The B component：C12-20 alkyl glucosides (1.5%), stearine (0.3%), three (ethyl hexyl of glycerine
Acid) ester (5%), dimethyl silicone polymer (1%), sad Propylheptyl (2%), ring five dimethyl silicone polymer (2%), flash
Bar seed oil (1%)；
The C component：Triethanolamine (0.1%), Echinacea angustifolia extract (0.8%), Acer negundo extract (1.2%),
Saccharomycete/rice fermentation Product filtrate (0.92%), Cer NP (0.16%), Cer AP II (0.08%), neural acyl
Amine 1 (0.08%), lauroyl dilactic acid sodium (0.6%), phytosphingosine (0.08%), phytosterol (0.08%)；
The D component：Phenoxyethanol (0.4%), Nipasol 0.1%, essence (0.05%).
The property of important source material used in the present invention is as follows：
Purple coneflower (ECHINACEA PURPUREA) extract (SymFinity1298/ manufacturers Symrise)：
100% is natural, fresh plant source, and dry concentration extraction, contained Cichoric acid can effectively improve SIRT1 (deacetylase)
Activity plays the adjusting function to gene such as cell ageing apoptosis, sugared lipid metabolism, reaction of inflammation oxidation emergency that it is participated in,
To which generated in anti-oxidant, promotion hyaluronic acid etc. plays the role of controling in moisturizing.
Acer negundo (ACER SACCHARUM) extract (Maple Water/ manufacturers ICHIMARU)：It is derived from Canadian chief north
The Normal juice (age of tree 40 years or more, tree-walk 20CM or more) of some areas Ke Sheng sugar maple tree trunk, rich in polysaccharide, Ca, K, Mg, Mn,
Malic acid promotes fibroblast proliferation, so as to improve cell water content, skin transepidermal water loss, improves water content of stratum corneum,
In the outermost layer of skin --- enhance skin barrier function in terms of the water of cuticula.
Saccharomycete/rice fermentation Product filtrate (ferment filtrate FC01/ manufacturers Angel Yeast)：It is selected to originate from 30 ° of north latitude
The organic glutinous rice in Zhongxiang City of township of longevity, ferments through unartificial yeast, containing abundant oligosaccharides, organic acid (tartaric acid), amino acid, small point
Sub- peptides etc. can enter skin corium quickly through cutin lamellar spacing, promote fibroblastic activity and collagen, elastic force fine
Peacekeeping hyaluronic acid hyperplasia, active cell film water channel protein, endogenous increase the water content of skin.
Cer NP, Cer AP II, Cer EOS (SK-influx/ manufacturers Evonik)：From tonka bean,
Biotechnology production through saccharomycetes to make fermentation, therefrom selects pair of chemical constitution and naturally occurring ceramide in human skin
The consistent configuration of layer stereochemical structure, forms lipid backbone, affine with Stratum corneum lipids height, to enhance in terms of lipid
The transmission of skin barrier function, more conducively moisture and active matter.
Phytosterol (CardioAid/ manufacturers ADM):There is very high osmosis to skin, increases lipase active, have
The ability of reversed membrane fluidity is adjusted and controlled, skin surface moisture can be kept.
The beneficial effects of the present invention are：
1) lotion of the invention, the ingredient that moisturizing is combined are：Echinacea angustifolia extract, Acer negundo extract, saccharomycete/rice
Tunning filtrate, lauroyl dilactic acid sodium, Cer NP, Cer AP II, Cer EOS, phytosphingosine, plant
Sterol has the moistening effect up to 4-8h by optimizing the compounding and adding proportion of long-acting moisturizing complexing agent.
2) technical program of the present invention lies in, as a whole, the addition of solvent and moisturizing lubricant component, in conjunction with moisturizing
Combine the lipid backbone that ceramide is formed, form bilayer lipid membrane, it is high with skin bilayer lipid membrane compatibility, be conducive to moisture and
Active material infiltration, conveying enhance skin barrier function to improve moisture content of skin from inside to outside, and long-acting moisturizing is brought to imitate
Fruit.
Specific implementation mode
Below by specific preferred embodiment combination effete test embodiment, technical scheme of the present invention is made further specific
Illustrate, but the present invention is not limited in following embodiment.
A kind of emulsion compositions with long-acting moisture-keeping efficacy disclosed by the invention, containing long-acting moisturizing complexing agent, by matter
Percentages are measured, the long-acting moisturizing complexing agent includes：The Acer negundo extraction of the Echinacea angustifolia extract, 20-40% of 15-30%
Object, saccharomycete/rice fermentation Product filtrate of 15-30%, the Cer NP of 0.5-5%, 0.5-5% Cer AP II,
The plant of the Cer EOS of 0.5-5%, lauroyl the dilactic acid sodium, the phytosphingosine of 0.5-5%, 0.5-5% of 10-20%
Object sterol.The lotion of the present invention has the guarantor up to 4-8h by optimizing the compounding and adding proportion of long-acting moisturizing complexing agent
Wet effect.
Embodiment 1
A kind of lotion with long-acting moisture-keeping efficacy, by mass percentage, the lotion are by following raw material components structure
At：
A components：Water to100%, glycerine 3%, butanediol 5%, glycine betaine 1%, Sodium Hyaluronate 0.03%, carbomer
0.18%, methyl hydroxybenzoate 0.15%；
B components：The smooth olive oleate 0.5% of cetostearyl alcohol olive oleate 1%, sorb, saualane 4%, octyl
Polymethyl siloxane 1%, isononyl isononanoate 3%, ring five dimethyl silicone polymer 2%, C10-18 resin acid triglycerides
0.5%, Nipasol 0.1%；
C components：Aminomethyl propanol 0.1%, long-acting moisturizing complexing agent 12.0% (Echinacea angustifolia extract 2.58%, sugar
Maple extract 4.5%, saccharomycete/rice fermentation Product filtrate 2.4%, Cer NP 0.06%, Cer AP II
0.12%, Cer EOS 0.06%, lauroyl dilactic acid sodium 1.8%, phytosphingosine 0.24%, phytosterol
0.24%)；
D components：Phenoxyethanol 0.4%, essence 0.08%.
The preparation method of the above-mentioned emulsion compositions with long-acting moisture-keeping efficacy, includes the following steps：
1) A components by mass percentage, are weighed：Solvent (water, glycerine, butanediol), thickener (carbomer), preservative
(methyl hydroxybenzoate), skin conditioning agent (glycine betaine, Sodium Hyaluronate), are uniformly mixed；
2) B components by mass percentage, are weighed：Emulsifier (the smooth olive oleic acid of cetostearyl alcohol olive oleate, sorb
Ester), moisturizing grease (saualane, octyl polymethyl siloxane, isononyl isononanoate, ring five dimethyl silicone polymer, C10-18 fat
Acid glycerol three ester class, Nipasol) it is for use；
3) C components by mass percentage, are weighed：PH conditioning agents (aminomethyl propanol), long-acting moisturizing complexing agent (purple pine nut
Chrysanthemum extract, Acer negundo extract, saccharomycete/rice fermentation Product filtrate, Cer NP, Cer AP II, Cer EOS,
Lauroyl dilactic acid sodium, phytosphingosine, phytosterol, for use；
4) D components by mass percentage, are weighed：Preservative (Phenoxyethanol), aromatic (essence)
5) A components are heated to 80-85 DEG C, insulated and stirred is pumped into homogenizer, homogeneous (2500rpm) 5 after 30 minutes
Minute, it stirs 5 minutes, heat preservation defoaming；
6) B components are heated to 80-85 DEG C, melt complete, addition homogenizer, homogeneous (3000rpm) 5 minutes, stirring 5
Minute, cooling；
7) 45 DEG C are cooled to, C, D components are added, are stirred until homogeneous.
Embodiment 2
A kind of lotion with long-acting moisture-keeping efficacy, by mass percentage, the lotion are by following raw material components structure
At：
A components：Water to100%, glycerine 3%, 1,3- propylene glycol 5%, trehalose 1%, Sodium Hyaluronate 0.02%, Huang
Virgin rubber 0.05%, biological carbohydrate gum -1 0.5%, ammonium acryloyldime-thyltaurate/- 25 methacrylate of docosyl alcohol polyethers
0.5%；
B components：C12-20 alkyl glucosides 1.5%, stearine 0.3%, glycerine three (thylhexoic acid) ester
5%, dimethyl silicone polymer 1%, sad Propylheptyl 3%, ring five dimethyl silicone polymer 3%, Jojoba
(SIMMONDSIA CHINENSIS) seed oil；
C components：Citric acid 0.04, sodium citrate 0.01%, long-acting 15.0% (Echinacea angustifolia extract of moisturizing complexing agent
3.825%, Acer negundo extract 3.95%, saccharomycete/rice fermentation Product filtrate 3.85%, Cer NP 0.15%, nerve
Amide 6II 0.15%, it Cer EOS 0.075%, lauroyl dilactic acid sodium 2.25%, phytosphingosine 0.45%, plants
Object sterol 0.3%)；
D components：Potassium sorbate 0.2%, Phenoxyethanol 0.4%, essence 0.1%.
The emulsion compositions preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Embodiment 3
A kind of lotion with long-acting moisture-keeping efficacy, by mass percentage, the lotion are by following raw material components structure
At：
A：Water to100%, glycerine 3, polyglyceryl ether -26 2%, beta glucan 0.5%, chitosan 0.1%, Huang
Virgin rubber 0.08%, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer 0.1%, methyl hydroxybenzoate 0.15%；
B：Surfhope SE Cosme C 1216 1.%, stearine 0.3%, avocado (PERSEA GRATISSIMA) oil 4%,
PEG-100 stearates 0.7%, dimethyl silicone polymer 1.2%, sad Propylheptyl 3%, caprylic/capric triglyceride
3%, Nipasol 0.1%；
C：Triethanolamine 0.1%, long-acting moisturizing complexing agent 18.0% (Echinacea angustifolia extract 4.25%, Acer negundo extract
5.6%, saccharomycete/rice fermentation Product filtrate 4.23%, Cer NP 0.27%, Cer AP II 0.27%, nerve
Amide 1 0.14%, lauroyl dilactic acid sodium 2.7%, phytosphingosine 0.36%, phytosterol 0.18%)；
D：Phenoxyethanol 0.4%, Chlorphenesin 0.1%, essence 0.12%.
The emulsion compositions preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Embodiment 4
A kind of lotion with long-acting moisture-keeping efficacy, by mass percentage, the lotion are by following raw material components structure
At：
A：Water to100%, glycerine 4%, propylene glycol 4%, α-mannosan 2%, xylitol 0.2%, hydroxy-ethyl acrylate/
Sodium acryloyldimethyl taurate copolymers 0.7%；
B：C20-22 alcohol phosphate 2%, glycerine three (thylhexoic acid) ester 5%, dimethyl silicone polymer 0.8%, isononanoic acid
4% ester of different nonyl, ring five dimethyl silicone polymer 3%, Queensland nut (MACADAMIA TERNIFOLIA) seed oil 2%
C：Sodium hydroxide 0.12%, citric acid 0.04%, long-acting moisturizing complexing agent 20% (Echinacea angustifolia extract 5.0%,
Acer negundo extract 6.1%, saccharomycete/rice fermentation Product filtrate 3.6%, Cer NP 0.4%, Cer AP II
0.4%, Cer EOS 0.2%, lauroyl dilactic acid sodium 3.0%, phytosphingosine 1.0%, phytosterol 0.3%)
D：Sodium benzoate 0.2%, Phenoxyethanol 0.4%, essence 0.15%.
The emulsion compositions preparation method with long-acting moisture-keeping efficacy of the present embodiment is the same as embodiment 1.
Control group：
Certain commercially available lotion Z sample without long-acting moisturizing complexing agent
Effect experimental examples
1, effect example：Security test
30 volunteers are chosen, in enclosed type patch test method, about by each embodiment tested materials of 1-5 of the present invention
0.020-0.025mL and blank control group (deionized water) are placed in spot examination device, and external application medical adhesive tape is pasted on a subject left side
Right back removes tested material after 24 hours, after removing patch 0.5h, for 24 hours, 48h observe dermoreaction, press《Cosmetics
Technical specification of security》Dermoreaction grade scale records its result in (version in 2015).
Compared with the control group, product 0.5h of the present invention, for 24 hours, after 48h, have no rubefaction or the allergy such as erythema occur is applied
Phenomenon illustrates that lotion made from various embodiments of the present invention is safe, does not cause any bad phenomenon, see the table below shown in 1：
Table 1：Cosmetics human skin enclosed type patch experimental result
2, effect example：Moistening effect tests (8 hours)
With example formulations sample and control group, refer to reference to the evaluation of professional standard QB/T 4256-2011 cosmetics moisture-keeping efficacies
South measures keratoderma hydration content and instrument using instrument MOISTUREMETERSC MSC1212 (DELFIN)
TAPOMETER SWL5167 (DELFIN) measure transepidermal water loss rate score, measure respectively using 0h, 0.5h after sample, 1h, 2h,
The numerical value of five periods of 4h, 8h records data, obtains a result, be shown in Table 2 and table 3：
2 keratoderma hydration content of table changes (a.u)
| Time | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Control group Z |
| 0h | 30.24 | 30.22 | 30.18 | 30.32 | 30.25 |
| 0.5h | 50.61 | 63.17 | 65.56 | 66.68 | 42.44 |
| 1h | 61.37 | 65.28 | 78.34 | 82.91 | 50.52 |
| 2h | 70.35 | 83.32 | 87.73 | 93.96 | 60.81 |
| 4h | 59.49 | 70.17 | 72.55 | 78.68 | 38.63 |
| 8h | 52.62 | 60.17 | 64.82 | 67.23 | 35.57 |
The percutaneous water loss rate (g/m of 3 skin of table2h)
| Time | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Control group Z |
| 0h | 5.13 | 5.62 | 5.83 | 5.47 | 5.35 |
| 0.5h | 4.65 | 3.97 | 3.78 | 3.68 | 4.04 |
| 1h | 4.28 | 3.72 | 3.65 | 3.57 | 4.42 |
| 2h | 3.55 | 3.04 | 2.99 | 2.23 | 4.75 |
| 4h | 4.5 | 3.73 | 3.58 | 3.32 | 5.06 |
| 8h | 5.08 | 4.69 | 4.58 | 3.87 | 5.21 |
As shown in Table 2：1-4 of the embodiment of the present invention and control group Z, after using sample 0.5-2h, skin keratin
Layer hydration content has different degrees of promotion.After using 2h, keratoderma hydration content reaches most wherein embodiment 2-4
Big value, respectively 83.32,87.73 and 93.96 have significant difference compared with the maximum value 60.81 of control group Z.In addition, right
According to group Z using after 4-8h, keratoderma hydration content is already close to initial value, and various embodiments of the present invention, by 4-8h
After test, higher keratoderma hydration content is still maintained, illustrates various embodiments of the present invention, by optimizing long-acting moisturizing
The compounding and adding proportion of complexing agent have better more efficient moistening effect.
From the result of table 3 can with it is further seen that：Compared with control group Z, 2-4 of the embodiment of the present invention is using 0.5-2h
Afterwards, the percutaneous water loss rate of skin reduces more notable.After using 4-8h, the percutaneous water loss rate of control group Z skins is
Close to initial level, illustrate that control group Z does not have long-acting moistening effect.And various embodiments of the present invention are still protected after 4-8h
The percutaneous water loss rate of lower skin is hold, this further illustrates the present invention each embodiment, is adding long-acting moisturizing complexing agent
And after optimizing adding proportion, there is more long-acting water retention property.
The above described is only a preferred embodiment of the present invention, consider formulation cost, preferred embodiment 2 and implementation
Example 3, but be not intended to limit the present invention in any form, therefore it is every without departing from technical solution of the present invention content, according to this hair
Bright technical spirit still falls within the technology of the present invention to any simple modification, equivalent change and modification made by above example
In the range of scheme.
Claims (8)
1. a kind of lotion with long-acting moisture-keeping efficacy, it is characterised in that：Contain long-acting moisturizing complexing agent in the lotion, by matter
Percentages are measured, the long-acting moisturizing complexing agent is made of following components：
2. the lotion according to claim 1 with long-acting moisture-keeping efficacy, it is characterised in that：The lotion contains long-acting guarantor
Wet complexing agent, by mass percentage, the long-acting moisturizing complexing agent are made of following components：
3. the lotion according to claim 1 or 2 with long-acting moisture-keeping efficacy, it is characterised in that：The lotion also contains
Other raw materials, other described raw materials include solvent, emulsifier, moisturizing grease, stabilizer, pH adjusting agent, preservative, aromatic,
By mass percentage, the lotion is made of following raw material components：
4. the lotion according to claim 3 with long-acting moisture-keeping efficacy, it is characterised in that：By mass percentage, institute
Lotion is stated to be made of following raw material components：
5. the lotion according to claim 4 with long-acting moisture-keeping efficacy, it is characterised in that：The solvent is selected from water, sweet
Oil, butanediol, 1,3- propylene glycol, dipropylene glycol, one kind in polyglyceryl ether -26 or their mixture；
The emulsifier is selected from cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, stearine, PEG-100
It is stearate, C12-20 alkyl glucosides, C20-22 alcohol phosphate, PEG-10 iso stearic acid of glycerine ester, Surfhope SE Cosme C 1216, sweet
Oleostearin acid esters citrate, one kind in polyglycereol-3-methyl distearate or their mixture；
The moisturizing grease is selected from saualane, glycerine three (thylhexoic acid) ester, avocado oil, octyl polymethyl siloxane, isononanoic acid
Different nonyl ester, caprylic/capric triglyceride, jojoba seed oil, sad Propylheptyl, ring five dimethyl silicone polymer, cetanol,
C10-18 resin acids triglyceride, dimethyl silicone polymer, one kind in Queensland nut seed oil or their mixture；
The stabilizer is selected from carbomer, xanthans, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer, third
Alkene acyl dimethyltaurine ammonium/VP copolymers, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, acryloyl two
One kind in N-methyltaurine ammonium/- 25 Methacrylate Crosspolymer of docosyl alcohol polyethers or their mixture；
The pH adjusting agent is in citric acid, sodium citrate, sodium hydroxide, triethanolamine, aminomethyl propanol, tromethamine
One kind or their mixture；
It is more that the skin conditioning agent is selected from glycine betaine, trehalose, Sodium Hyaluronate, beta glucan, α-mannosan, deacetylated shell
Sugar, biological carbohydrate gum -1, levulan, xylitol or their mixture；
The preservative is selected from methyl hydroxybenzoate, Nipasol, potassium sorbate, sodium benzoate, Chlorphenesin, Phenoxyethanol；
The aromatic is selected from containing the few plant flowers fruity of anaphylactogen.
6. the lotion according to claim 5 with long-acting moisture-keeping efficacy, it is characterised in that：The pH adjusting agent control breast
Between the pH of liquid ranging from 5.5-6.5.
7. the preparation method of the lotion with long-acting moisture-keeping efficacy described in claim 5, which is characterized in that including walking as follows
Suddenly：
1) the A item components of 56-75% by mass percentage, are weighed：Solvent, stabilizer, skin conditioning agent, are uniformly mixed；
2) the B item components of 11-25% by mass percentage, are weighed：Emulsifier, moisturizing grease, for use；
3) the C item components of 12.5-18.2% by mass percentage, are weighed：PH conditioning agents, long-acting moisturizing complexing agent, for use；
4) the D item components of 0.45-1.2% by mass percentage, are weighed：Preservative, aromatic, for use；
5) A components being heated to 80-85 DEG C, insulated and stirred is after 30 minutes, suction homogenizer, homogeneous (2500rpm) 5 minutes,
Stirring 5 minutes, heat preservation defoaming；
6) B components are heated to 80-85 DEG C, melt complete, addition homogenizer, homogeneous (3000rpm) 5 minutes, 5 points of stirring
Clock, cooling；
7) 45 DEG C are cooled to, C, D components are added, are stirred until homogeneous.
8. the preparation method of the lotion according to claim 7 with long-acting moisture-keeping efficacy, it is characterised in that：
The A component：Water (To 100%), glycerine (5%), butanediol (3%), ethyl alcohol (2%), carbomer (0.1%), Huang
Virgin rubber (0.1%), methyl hydroxybenzoate (0.2%), Phenoxyethanol (0.4%)；
The B component：C12-20 alkyl glucosides (1.5%), stearine (0.3%), glycerine three (thylhexoic acid)
Ester (5%), dimethyl silicone polymer (1%), sad Propylheptyl (2%), ring five dimethyl silicone polymer (2%), Jojoba
Seed oil (1%)；
The C component：Triethanolamine (0.1%), Echinacea angustifolia extract (0.8%), Acer negundo extract (1.2%), yeast
Bacterium/rice fermentation Product filtrate (0.92%), Cer NP (0.16%), Cer AP II (0.08%), Cer EOS
(0.08%), lauroyl dilactic acid sodium (0.6%), phytosphingosine (0.08%), phytosterol (0.08%)；
The D component：Phenoxyethanol (0.4%), Nipasol 0.1%, essence (0.05%).
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109303746A (en) * | 2018-12-13 | 2019-02-05 | 广州环亚化妆品科技有限公司 | A kind of prebiotic compositions and its preparation method and application |
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| CN109528579A (en) * | 2018-11-22 | 2019-03-29 | 广州艾蓓生物科技有限公司 | A kind of emulsion spray and preparation method thereof of moisturizing reparation |
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| TWI833492B (en) * | 2022-12-07 | 2024-02-21 | 佳妙國際股份有限公司 | Lotion composition |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104000756A (en) * | 2014-01-08 | 2014-08-27 | 惠州孕美生物科技有限公司 | Hydrating moistening cosmetic containing rice extract and preparation method thereof |
| CN105326678A (en) * | 2015-10-28 | 2016-02-17 | 嘉兴市蝶柔化妆品有限公司 | Multi-effect ceramide face cream |
| CN106109392A (en) * | 2016-06-27 | 2016-11-16 | 上海乐宝日化股份有限公司 | Biofibre facial mask |
| CN106726969A (en) * | 2016-12-27 | 2017-05-31 | 广东芭薇生物科技股份有限公司 | A kind of composition of gentle exfoliating and preparation method thereof |
| CN107184499A (en) * | 2017-04-12 | 2017-09-22 | 广州环亚化妆品科技有限公司 | A kind of long-acting moisturizing emulsion mask composition of natural botanical source and preparation method thereof |
| CN107569402A (en) * | 2017-09-30 | 2018-01-12 | 惠州东慧新材料制品有限公司 | A kind of long-acting moisture-keeping composition |
| CN108096143A (en) * | 2017-12-28 | 2018-06-01 | 广州蜜妆生物科技有限公司 | A kind of toner containing active ingredient of Chinese herbs and yeast |
-
2018
- 2018-07-02 CN CN201810707169.9A patent/CN108524399A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104000756A (en) * | 2014-01-08 | 2014-08-27 | 惠州孕美生物科技有限公司 | Hydrating moistening cosmetic containing rice extract and preparation method thereof |
| CN105326678A (en) * | 2015-10-28 | 2016-02-17 | 嘉兴市蝶柔化妆品有限公司 | Multi-effect ceramide face cream |
| CN106109392A (en) * | 2016-06-27 | 2016-11-16 | 上海乐宝日化股份有限公司 | Biofibre facial mask |
| CN106726969A (en) * | 2016-12-27 | 2017-05-31 | 广东芭薇生物科技股份有限公司 | A kind of composition of gentle exfoliating and preparation method thereof |
| CN107184499A (en) * | 2017-04-12 | 2017-09-22 | 广州环亚化妆品科技有限公司 | A kind of long-acting moisturizing emulsion mask composition of natural botanical source and preparation method thereof |
| CN107569402A (en) * | 2017-09-30 | 2018-01-12 | 惠州东慧新材料制品有限公司 | A kind of long-acting moisture-keeping composition |
| CN108096143A (en) * | 2017-12-28 | 2018-06-01 | 广州蜜妆生物科技有限公司 | A kind of toner containing active ingredient of Chinese herbs and yeast |
Non-Patent Citations (1)
| Title |
|---|
| 裘炳毅 等编著: "《现代化妆品科学与技术》", 31 March 2016 * |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109528579A (en) * | 2018-11-22 | 2019-03-29 | 广州艾蓓生物科技有限公司 | A kind of emulsion spray and preparation method thereof of moisturizing reparation |
| CN109528579B (en) * | 2018-11-22 | 2021-07-27 | 广州艾蓓生物科技有限公司 | Moisturizing and repairing emulsion spray and preparation method thereof |
| CN109303746B (en) * | 2018-12-13 | 2021-05-28 | 广州环亚化妆品科技有限公司 | Prebiotic composition and preparation method and application thereof |
| CN109303746A (en) * | 2018-12-13 | 2019-02-05 | 广州环亚化妆品科技有限公司 | A kind of prebiotic compositions and its preparation method and application |
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| CN112370408A (en) * | 2020-12-14 | 2021-02-19 | 广州环亚化妆品科技有限公司 | Composition with high-power moisturizing effect and application of composition in cosmetics |
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| TWI833492B (en) * | 2022-12-07 | 2024-02-21 | 佳妙國際股份有限公司 | Lotion composition |
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Application publication date: 20180914 |