CN108451835A

CN108451835A - A kind of preparation method of eucommia bark toothpaste

Info

Publication number: CN108451835A
Application number: CN201810659025.0A
Authority: CN
Inventors: 王斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-06-13
Filing date: 2018-06-13
Publication date: 2018-08-28

Abstract

The invention discloses a kind of preparation methods of eucommia bark toothpaste.It is primarily characterized in that, drug extract is first made by folium cortex eucommiae and dandelion, Asiatic plantain, then said medicine medicinal extract and lotion of toothpaste matrix are made by mixing with 0.2 0.5: 100 ratio.The present invention especially has significant curative effect to recurrent oral ulceration also known as recurrent aphthous ulcer and decayed tooth and periodontosis；The present invention enriches the utilization ways of folium cortex eucommiae, and the also research and development for oral care type toothpaste provide approach and Research Thinking.

Description

A kind of preparation method of eucommia bark toothpaste

Technical field

The present invention relates to a kind of toothpaste and preparation method thereof, especially a kind of eucommia bark toothpaste and preparation method thereof.

Technical background

Toothpaste is common oral cavity nursing health products in daily life, and more is anti-inflammatory toothpaste and antiseptic toothpaste, with Reach antiplaque, inhibiting bacteria and diminishing inflammation.Canker sore, that is, we " aphtha " often said, be the superficial being happened on mucous membrane of mouth Property ulcer., can be in great pain when serious although what serious disease is canker sore be not, influence diet and work and rest.Present medicine and Science and technology is so flourishing, and in fact in addition to conventional drug therapy, we can also prevent and treat canker sore by toothpaste.

Invention content：

It is an object of the present invention to provide a kind of completely new healthy toothpaste to people, enrich folium cortex eucommiae utilizes way Diameter, the also research and development for oral care type toothpaste provide approach and Research Thinking.

In order to solve the above technical problems, the present invention is realized using following technical scheme：A kind of eucommia bark toothpaste, by weight, Drug extract is first made by 10~20 parts of folium cortex eucommiae and dandelion 5~10,5~10 parts of Asiatic plantain,

By weight, said medicine medicinal extract again with lotion of toothpaste matrix with 0.2~0.5: 100 ratio is made by mixing and At；

The production method of said medicine medicinal extract is：

(1), folium cortex eucommiae, dandelion, Asiatic plantain are mixed, after drying, crushing, crosses 100~200 mesh sieve, be then added Feed liquid is made in the water that 5~10 times of raw material weight；Infiltration 1 hour, adjustment pH value of solution are heated to 55 DEG C~75 DEG C after being 5.5~7.5, By every 100g folium cortex eucommiaes, dandelion, Asiatic plantain mixture in terms of, be added amylase 600U~900U, the constant temperature at above-mentioned temperature Stirring 1 hour；

(2), the operation temperature of step 1) is risen to 100 DEG C, is filtered after decocting 1 hour, obtains concoction and the dregs of a decoction；It will be above-mentioned Feed liquid is placed in closed container, and then passing to carbon dioxide gas makes container inner pressure be 1~3MPa, keeps 10~20min, so Pressure release is carried out to normal pressure state to closed container afterwards, collects feed liquid in common vessel；

(3), the concoction obtained, it is 3.5~4.5 to adjust its pH, 55 DEG C~60 DEG C is heated to, with every 100g folium cortex eucommiaes, Pu Public English, Asiatic plantain mixture meter, be added carbohydrase 15000U~25000U, at above-mentioned temperature constant temperature stir 1 hour；So Feed liquid is centrifuged afterwards, rotating speed is 3500~4500r/min, 5~10min of time, to the supernatant after centrifugation It is concentrated under reduced pressure, obtains medicinal extract.

Drug of the present invention includes folium cortex eucommiae, dandelion, Asiatic plantain, wherein contains lignanoids, cyclenes in folium cortex eucommiae Ether terpene, Phenylpropanoid Glycosides class, flavonoids, amino acid, polysaccharide, vitamin and mineral element Zn, Mn, Cu, Fe, Ca, P, B, Mg, K Deng, have the function of strength promote and maintaining healthy.Its function is：

1, anti-oxidant folium cortex eucommiae can promote the synthesis and decomposition of collagen in human skin, bone and muscle, promote generation It thanks.

2, contain abundant chlorogenic acid in antibacterial anti-inflammatory folium cortex eucommiae, content reaches 2.5-5.28%, has extensive antibacterial, emerging Put forth energy nervous centralis, promote bile and gastric secretion, hemostasis, improve quantity of leucocyte and antiviral effect.

3, there is good astriction containing 5.4% tanning matter in hemostasis, analgesia, anti-corrosion folium cortex eucommiae, it can The surface for acting on mucous membrane and wound makes local vasoconstriction, inhibits Bodily secretions matter to be intended to the activity of white blood cell, and prevent group Hyperemia is knitted, to play hemostasis, analgesia, anti-corrosion, anti-inflammatory and other effects.

4, prevent decayed tooth and the magnesium containing 1.51% calcium, 280 milligrams/100 grams in strong bone folium cortex eucommiae, both Ingredient is exactly the neccessary composition for preventing decayed tooth and strong bone.

5, tooth mobility is prevented, treatment periodontosis folium cortex eucommiae has promotion collagen synthesis and improves metabolism The effect of.There are many reason of generating periodontosis, wherein being especially most with the bacteriogenic situation of tartar.Gum is like support The earth of tooth, once suffering from periodontosis, gum will inflammation and abscess.And gum, gum film, gum bone, interdental knot Mixture has collagen to be constituted.After taking folium cortex eucommiae substance, the metabolic function of collagen will be promoted, because This just makes gum muscle tight, can eliminate various focusing depths represented, and keeps tooth solid.

Dandelion has extensive pharmacological activity, especially antibacterial action more notable.It has broad-spectrum antibacterial action, to gold Yellow staphylococcus, hemolytic streptococcus have stronger bactericidal effect, to Diplococcus pneumopniae, meningococcus, corynebacterium diphtheriae, green pus Bacillus, shigella dysenteriae, typhoid bacillus also have certain biocidal efficacies.Asiatic plantain is cold in nature, sweet in flavor, containing abundant dietary fiber, calcium, The substances such as phosphorus, carrotene, choline, sylvite, citric acid, oxalic acid, three kinds of drug folium cortex eucommiaes, dandelion, Asiatic plantain ingredient not phase Gram, their active ingredients are released, it is better.

The present invention especially has significantly recurrent oral ulceration also known as recurrent aphthous ulcer and decayed tooth and periodontosis Curative effect.L-type streptococcus is hemolytic streptococcus, it becomes the protoplast with drug resistance under the action of certain drug, is dived Volt is in the cell, it is not easy to which drug kills.But this bacterium can become hemolytic streptococcus under appropriate conditions, lead to oral cavity Ulcer recurrent exerbation.And hemolytic streptococcus then can be effectively killed using the present invention, it can effectively capture the oral cavities such as canker sore Disease.

The present invention can shorten healing, prevent decayed tooth, treatment periodontosis, and to mitigate pain degree, patient is fast Then a couple of days fully recovers, and then fully recovers within three or four days slowly.Regrettably, the time interval that canker sore recurs is not made using the present invention Shorten, but the healing canker sore that using every time can be quickly, drug effect is not to bate a jot of one's demands.Pay attention to：The present invention should be used continuously, and And it is uninterrupted, it otherwise can impact effect.Because L-type streptococcus drug resistance is stronger, the drug effect remained in the oral cavity can play one The effect in entire evening, can effectively inhibit the hyperplasia of harmful bacteria in patient oral cavity.The present invention is by folium cortex eucommiae, dandelion, vehicle As drug ingedient toothpaste is made in preceding grass, also with clearing heat and detoxicating, antibacterial, it is anti-inflammatory, tonify the liver and kidney and other effects.

Applicant has carried out a large amount of research to the manufacturing technology of toothpaste, as applicant once respectively with folium cortex eucommiae, dandelion, Toothpaste is made as drug ingedient in Asiatic plantain, as a result, it has been found that folium cortex eucommiae, dandelion, Asiatic plantain combine in the proper ratio is used as medicine Toothpaste made of object ingredient, than folium cortex eucommiae, dandelion, Asiatic plantain individually as toothpaste antibacterial effect made of drug ingedient More preferably.

Specific implementation mode：

Invention is further described with reference to embodiment, but is not intended as the foundation limited the present invention.

With every lotion of toothpaste matrix weight 100g,

It calculates by weight, drug extract is first made by 20 parts of folium cortex eucommiae and 10 parts of dandelion, 10 parts of Asiatic plantain, takes drug Medicinal extract 0.5g

The preparation method of above-mentioned eucommia bark toothpaste, includes the following steps：

(1) glue：First by 10~20 parts of glycerine, 7~12 parts of 5~11 parts of sorbierite and deionized water are stirred until homogeneous；

(2) cream processed：Drug extract is added, is stirred until homogeneous；It is separately added into 40~50 parts of calcium carbonate, silica again 10~20 parts, 2~3 parts of lauryl sodium sulfate stirs 30min, emulsifying 10~20min, filling.

Claims

1. a kind of preparation method of eucommia bark toothpaste, it is characterised in that：By weight, by 10~20 parts of folium cortex eucommiae and dandelion 5~ 10, drug extract is first made in 5~10 parts of Asiatic plantain,

By weight, said medicine medicinal extract is made by mixing with lotion of toothpaste matrix with 0.2~0.5: 100 ratio again；

The production method of said medicine medicinal extract is：

(1), folium cortex eucommiae, dandelion, Asiatic plantain are mixed, after drying, crushing, crosses 100~200 mesh sieve, raw material is then added Feed liquid is made in the water that 5~10 times of weight；Infiltration 1 hour, adjustment pH value of solution is heated to 55 DEG C~75 DEG C after being 5.5~7.5, with every 100g folium cortex eucommiaes, dandelion, Asiatic plantain mixture meter, be added amylase 600U~900U, at above-mentioned temperature constant temperature stirring 1 Hour；

(2), the operation temperature of step 1) is risen to 100 DEG C, is filtered after decocting 1 hour, obtains concoction and the dregs of a decoction；By above-mentioned feed liquid It is placed in closed container, then passing to carbon dioxide gas makes container inner pressure be 1~3MPa, keeps 10~20min, then right Closed container carries out pressure release to normal pressure state, collects feed liquid in common vessel；

(3), the concoction obtained, adjust its pH be 3.5~4.5, be heated to 55 DEG C~60 DEG C, with every 100g folium cortex eucommiaes, dandelion, Carbohydrase 15000U~25000U is added in the mixture meter of Asiatic plantain, and constant temperature stirs 1 hour at above-mentioned temperature；Then to material Liquid is centrifuged, and rotating speed is 3500~4500r/min, and 5~10min of time subtracts the supernatant after centrifugation Pressure concentration, obtains medicinal extract.