CN108159191A - Composition, purposes and oral liquid of kidney and preparation method thereof are good in establishing-Yang - Google Patents

Abstract

Composition, purposes and oral liquid of kidney and preparation method thereof is good for the present invention provides a kind of establishing-Yang, it is related to field of health care products, the establishing-Yang is good for kidney composition and includes lycium ruthenicum, Hei Maka, Herba Cistanches, cordyceps sinensis, Cortex Eucommiae, ganoderma lucidum, cynomorium songaricum, lotus seeds, snow chrysanthemum, hawthorn, American Ginseng, red matrimony vine and honey, has effects that kidney is good in antifatigue, anti-oxidant and establishing-Yang.Also had effects that using oral liquid made from above-mentioned composition identical and convenient.The preparation method of the oral liquid can make raw material give full play to effect, have industrial value.The present invention, which alleviates shortage one kind in the prior art, can effectively alleviate male's sub-health state, and the problem of the health products with establishing-Yang kidney strengthening effect.

Description

Composition, purposes and oral liquid of kidney and preparation method thereof are good in establishing-Yang

Technical field

The present invention relates to field of health care products, more particularly, to a kind of establishing-Yang be good for kidney composition, purposes and oral liquid and its Preparation method.

Background technology

The health problem and inferior health problem getting worse that male faces.It is investigated according to the World Health Organization, has 78% all City male unsoundness problem or state in " inferior health " in terms of body ＆ mind.And in " inferior health " group, man Ratio shared by property is up to 75%.

Modern male has five big pain spots in terms of health：First, chronic stress is big and causes kidney deficiency deficiency of the kidney, soreness of waist leg is stranded, under Myasthenia of limbs, the weary god of gas is tired, and spirit is insufficient, and sexual disorder or obstacle influence physically and mentally healthy and family harmony.It is second is that long-term super Load operation and diet, irregular, lack of exercise of working and resting cause the deficiency of vital energy fat, and overweight, blood pressure, blood glucose, blood fat, uric acid occupy It is high not under, the health risks such as cancer, hypertension, diabetes, goat, cardiovascular and cerebrovascular disease, sudden death increase considerably.Third, work Make and family's pressure causes greatly spirit to enter overload operation state, " heart tires out " shortness of breath is nervous, anxious, melancholy lonely Solely, mood is repeatedly.Medical clinical practice and scientific research prove that for example anxiety, animosity, sadness, fear, indignation etc. can for negative feeling So that the imbalance of each systematic function of human body, can cause forgetful insomnia, tachycardia, blood pressure raising, anorexia, dim eyesight it is dizzy, It feels exhausted the bad body reflection such as unbearably.If human body is chronically at " inferior health " state, substance is just easily lead to Lesion.Fourth, the bad life habits such as dinner party of drinking, smoking and hobby, substance is caused for heart, liver, the bottom of heart, pancreas Lesion influence, there is a series of body adverse reaction.Go down for a long time, cancer, four "high" diseases, cardiovascular and cerebrovascular disease, kidney Many high-risk disease incidences such as disease, hepatopathy, prostate, sex dysfunction are very high, and middle-aged male healthy hidden danger is very big, illness It is very high with mortality risk.Fifth, urban natural environment and working environment deteriorate, the air of high pollution, various harmful substances weight are residual The food that stays, various noise jamming, computer, mobile phone and various high electromagnetic radiation, waste water, exhaust gas, noise, radiation etc., all The physical and mental health of male is caused huge harm, various internal organs burdens are very heavy, usually can't bear the heavy load, and are easy to generate disease Become, so as to form huge threat to health.

Therefore, it is necessary to provide the inferior health problem that the health products that kidney is good in a kind of establishing-Yang alleviate male.

In view of this, it is special to propose the present invention.

Invention content

The first object of the present invention is to provide the composition that kidney is good in a kind of establishing-Yang, and the second object of the present invention is to provide A kind of purposes of above-mentioned composition in health products and drug are prepared, the third object of the present invention are to provide a kind of using above-mentioned Oral liquid of the composition as raw material, the fourth object of the present invention are to provide a kind of preparation method of above-mentioned oral liquid, alleviate Shortage one kind in the prior art can effectively alleviate male's sub-health state, and the guarantor with establishing-Yang kidney strengthening effect The problem of strong product.

In order to solve the above technical problems, spy of the present invention adopts the following technical scheme that：

The composition of kidney is good in a kind of establishing-Yang, and the composition is counted in parts by weight comprising following component：Lycium ruthenicum 25-250 Part, 5-55 parts of black agate card, 5-20 parts of Herba Cistanches, 5-15 parts of cordyceps sinensis, 10-20 parts of Cortex Eucommiae, 5-10 parts of ganoderma lucidum, cynomorium songaricum 5-15 Part, 5-10 parts of lotus seeds, 2-10 parts of snow chrysanthemum, 5-15 parts of hawthorn, 5-15 parts of American Ginseng, red matrimony vine 15-120 parts and 5-15 parts of honey.

Further, the lycium ruthenicum includes lycium ruthenicum dry product and/or lycium ruthenicum fresh goods；And/or the red matrimony vine includes Red matrimony vine dry product and/or red matrimony vine fresh goods；

Preferably, the composition includes lycium ruthenicum dry product 25-50 parts by weight, preferably 25-40 parts by weight, more preferably 25-35 parts by weight；

Preferably, the composition includes lycium ruthenicum fresh goods 50-200 parts by weight, preferably 100-200 parts by weight, more excellent It is selected as 150-200 parts by weight；

Preferably, the composition includes red matrimony vine dry product 15-45 parts by weight, preferably 15-35 parts by weight, more preferably 18-25 parts by weight；

Preferably, the composition includes red matrimony vine fresh goods 45-75 parts by weight, preferably 50-65 parts by weight, more preferably 55-65 parts by weight.

Further, the composition further includes one or more in Radix Notoginseng, ginseng and wilsonii；

Preferably, the composition includes Radix Notoginseng 5-15 parts by weight, preferably 8-12 parts by weight, more preferably 9-11 weight Part；

Preferably, the composition includes ginseng 2-10 parts by weight, preferably 4-9 parts by weight, more preferably 5-8 weight Part；

Preferably, the composition includes wilsonii 5-20 parts by weight, preferably 8-15 parts by weight, more preferably 9-12 weights Measure part.

Further, the honey includes medlar nectar.

Further, the composition includes black agate card 8-30 parts by weight, Herba Cistanches 6-15 parts by weight, cordyceps sinensis 6-10 Parts by weight, Cortex Eucommiae 12-18 parts by weight, ganoderma lucidum 6-9 parts by weight, cynomorium songaricum 7-12 parts by weight, lotus seeds 6-9 parts by weight, snow chrysanthemum 3-8 weight Part, hawthorn 8-12 parts by weight, American Ginseng 6-12 parts by weight and honey 8-12 parts by weight；

Preferably, the composition includes black agate card 8-15 parts by weight, Herba Cistanches 8-12 parts by weight, cordyceps sinensis 7-11 weights Measure part, Cortex Eucommiae 14-16 parts by weight, ganoderma lucidum 7-8 parts by weight, cynomorium songaricum 8-11 parts by weight, lotus seeds 7-9 parts by weight, snow chrysanthemum 4-6 weight Part, hawthorn 9-11 parts by weight, American Ginseng 7-10 parts by weight and 9-11 parts of honey.

A kind of purposes of above-mentioned composition in health products and drug are prepared, the purposes include it is antifatigue, anti-oxidant and Kidney is good in establishing-Yang.

A kind of oral liquid, the raw material of the oral liquid include above-mentioned composition.

Further, one kind in the extract of the raw material including raw slurry, the soak of raw material and raw material or It is a variety of.

The step of preparation method of above-mentioned oral liquid, the preparation method includes mixing each raw material according to formula ratio.

Further, the preparation method includes the following steps：

(a) by Hei Maka, Herba Cistanches, cynomorium songaricum, American Ginseng, lycium ruthenicum, red matrimony vine, snow chrysanthemum, Cortex Eucommiae, lotus seeds, the other powder of hawthorn It is broken, it then impregnates, then squeeze the juice；

(b) ganoderma lucidum is crushed to 100-120 mesh；

(c) it is filtered after component, honey and the Cordyceps extract in step (a) and step (b) are mixed by formula ratio, Sterilizing；

Preferably, the raw material handled in the step (a) further includes a kind of or more in ginseng, Radix Notoginseng and wilsonii Kind；

Preferably, the step (a) further includes following steps：First mashing processing is squeezed the juice again after each component crushes immersion, is squeezed The step of slurries obtained after juice are centrifuged, deaerate, filter, sterilize and are concentrated in vacuo successively obtains the raw material slurry of each component Liquid.

Compared with prior art, the present invention has the advantages that：

The composition of kidney is good in establishing-Yang provided by the invention, including lycium ruthenicum, Hei Maka, Herba Cistanches, cordyceps sinensis, Cortex Eucommiae, Ganoderma lucidum, cynomorium songaricum, lotus seeds, snow chrysanthemum, hawthorn, American Ginseng, red matrimony vine and honey.The composition is directed to middle-aged male physical condition, with Enough lycium ruthenicums supplements the high-quality anthocyanidin of human body, enhances body immunity, improves that body is anti-oxidant, ability of anti-aging, and Human free radical can be removed, alleviates visual fatigue, beautifying face and moistering lotion, the endocrine of balance body, protection cardiovascular and cerebrovascular, improve in human body Cycle.The composition is with Hei Maka, Herba Cistanches, Cortex Eucommiae, cynomorium songaricum temperature compensation kidney, nourishing and strengthening Yin and Yang, loins-strengthening and kidney-invigorating；With red matrimony vine, winter Worm summer grass, ganoderma lucidum, American Ginseng, honey nourishing essence, gas, blood and the deficient deficit of various bodies, tune fill blood, build up health；With lotus Son, snow chrysanthemum, hawthorn, which are adjusted, to be entirely formulated hot, is reached not dry and is not trembled with fear, and puts down that profit is flat to mend, remove rubbish toxin that body generates, Toxin-expelling and face nourishing, blood lipid-reducing blood sugar-decreasing, promoting blood circulation and removing blood stasis, clearing away the heart fire and tranquillizing.It is built up health, had anti-ageing by synergistic effect between each component Always, anti-oxidant, removing human free radical, warming and invigorating kidney Yang, tune fill blood, adjust human body yin-yang balancing, toxin-expelling and face nourishing, clearing away the heart fire and tranquillizing Effect.

Purposes of the above-mentioned composition provided by the invention in health products and drug are prepared, including antifatigue, anti-oxidant and Kidney is good in establishing-Yang.Above-mentioned composition can be applied to prepare the various health products or drug for alleviating male's inferior health, can prepare health care The health products of the diversified forms such as wine, health care oral liquid, can be used for preparing in the diversified forms such as pill, paste or tablet into Medicine.

Oral liquid provided by the invention, using above-mentioned Chinese medicine composition as raw material, whole health cares with above-mentioned composition are imitated Fruit, it is convenient also to have the advantages that drink.

The preparation method of above-mentioned oral liquid provided by the invention, the good health care for remaining bulk pharmaceutical chemicals and therapeutic effect, And it is suitble to large-scale production, there is great industrial value.

Description of the drawings

It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution of the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in being described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, can also be obtained according to these attached drawings other attached drawings.

Fig. 1 is the technological process for preparing oral liquid that the embodiment of the present invention 6 provides.

Specific embodiment

Technical scheme of the present invention is clearly and completely described below in conjunction with embodiment and attached drawing, it is clear that retouched The embodiment stated is part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field Those of ordinary skill's all other embodiments obtained without making creative work, belong to protection of the present invention Range.

The present invention provides the composition that kidney is good in a kind of establishing-Yang, the composition is counted in parts by weight comprising following component： 25-250 parts of lycium ruthenicum, 5-55 parts of black agate card, 5-20 parts of Herba Cistanches, 5-15 parts of cordyceps sinensis, 10-20 parts of Cortex Eucommiae, ganoderma lucidum 5-10 Part, 5-15 parts of cynomorium songaricum, 5-10 parts of lotus seeds, 2-10 parts of snow chrysanthemum, 5-15 parts of hawthorn, 5-15 parts of American Ginseng, it is red matrimony vine 15-120 parts and 5-15 parts of honey.

The Chinese tradition traditional Chinese medical science thinks that black food (medicine) product enter kidney, it is intended that black-food has the healthcare function that strong kidney is good for kidney. The present invention preferably by the use of the produced lycium ruthenicum in the Qinghai Province Caidamu Basin, three kinds of black medicine (food) raw materials of Hei Maka and Herba Cistanches as Entirely it is formulated anti-oxidant, anti-aging, the pharmacological basis of kidney is good in establishing-Yang.

For middle-aged male physical condition, the composition provides basic effect with anthocyanidin, and people is supplemented with enough lycium ruthenicums The high-quality anthocyanidin of body enhances body immunity, improves anti-oxidant body, anti-aging and the ability for removing human free radical, also has Have and alleviate visual fatigue, beautifying face and moistering lotion, the endocrine of balance body, protection cardiovascular and cerebrovascular, improve the effect of people's body-internal-circulation；With black agate Card, Herba Cistanches, Cortex Eucommiae, cynomorium songaricum temperature compensation kidney, nourishing and strengthening Yin and Yang, loins-strengthening and kidney-invigorating；With red matrimony vine, cordyceps sinensis, ganoderma lucidum, American Ginseng, Honey nourishing essence, gas, blood and the deficient deficit of various bodies, tune fill blood, build up health；It is adjusted with lotus seeds, snow chrysanthemum flower, hawthorn whole A formula it is hot, reach not dry and do not tremble with fear, put down that profit is flat to mend, remove rubbish toxin, toxin-expelling and face nourishing, blood lipid-reducing blood sugar-decreasing that body generates, Promoting blood circulation and removing blood stasis and clearing away the heart fire and tranquillizing effect by the synergistic effect between each component, has given play to entire formula and has built up health, is anti-ageing Always, it is anti-oxidant, remove human free radical, warming and invigorating kidney Yang, tune fill blood, adjust human body yin-yang balancing, toxin-expelling and face nourishing and the peace that clears away heart-fire The effect of god.

In one optionally embodiment, the lycium ruthenicum includes lycium ruthenicum dry product and/or lycium ruthenicum fresh goods；It is optional Ground, the composition include lycium ruthenicum dry product 25-50 parts by weight, such as can be but be not limited to 20,25,30,40 or 50 Parts by weight, preferably 25-35 parts by weight；Optionally, the composition includes lycium ruthenicum fresh goods 50-200 parts by weight, such as can be with For but be not limited to 50,60,70,80,90,100,110,120,130,140,150,160,170,180,190 or 200 weight Part, preferably 150-200 parts by weight.

In one optionally embodiment, the red matrimony vine includes red matrimony vine dry product and/or red matrimony vine fresh goods；It is optional Ground, the composition include red matrimony vine dry product 15-45 parts by weight, such as can be but be not limited to 15,25,35 or 45 weight Part, preferably 18-25 parts by weight；Optionally, the composition include red matrimony vine fresh goods 45-75 parts by weight, such as can be but It is not limited to 45,50,60,70 or 75 parts by weight, preferably 55-65 parts by weight.

In one optionally embodiment, the Hei Maka for example can be but be not limited to 5,15,25,40 or 55 Parts by weight, preferably 8-15 parts by weight；Optionally, the Herba Cistanches for example can be but be not limited to 5,15 or 20 weight Part, preferably 8-12 parts by weight；Optionally, the cordyceps sinensis for example can be but be not limited to 5,10 or 15 parts by weight, Preferably 7-11 parts by weight；Optionally, the Cortex Eucommiae for example can be but be not limited to 10,12,15 or 20 parts by weight, preferably For 14-16 parts by weight；Optionally, the ganoderma lucidum for example can be but be not limited to 5,8 or 10 parts by weight, and preferably 7-8 is heavy Measure part；Optionally, the cynomorium songaricum for example can be but be not limited to 5,10,12,15 or 20 parts by weight, preferably 8-11 weight Part；Optionally, the lotus seeds for example can be but be not limited to 5,8 or 10 parts by weight, preferably 7-9 parts by weight；Optionally, The snow chrysanthemum for example can be but be not limited to 2,8 or 10 parts by weight, preferably 4-6 parts by weight；Optionally, the hawthorn example It such as can be but be not limited to 5,10,12,15 or 20 parts by weight, preferably 9-11 parts by weight；Optionally, the American Ginseng example It such as can be but be not limited to 5,10,12,15 or 20 parts by weight, preferably 7-10 parts by weight；Optionally, the honey is for example It can be but be not limited to 5,10 or 15 parts by weight, preferably 9-11 parts by weight.

Establishing-Yang provided by the invention be good for each component in the composition of kidney have effects that it is as follows：

Lycium ruthenicum：Lycium ruthenicum contains lot of anthocyanin, and anthocyanidin is potent antioxidant, and normal cell can be maintained to connect Knot, the stabilization of blood vessel, enhancement fine vascular cycle, the flowing for improving capilary and vein.It is starched in the ripe atropurpureus of lycium ruthenicum In fruit, the ingredient of more than 20 kinds of anthocyanidin is had more than, wherein mainly there is 6 major class such as Cyanidin, petunidin, anthocyanidin has Six large effect below：1. pre- anti-cancer, anthocyanidin has effects that remove free radical, and cancer cell can be allowed to can not be successfully diffusion, borrowed The cell of the more health of this protection by cancer cell from being corroded.2. promoting eyesight, anthocyanidin can promote visual purple in retina cell The regeneration of matter promotes visual acuity, can prevent laser high myopia and detached retina, and can promote eyesight, and to view The damage of film gangliocyte has certain antagonism.3. anthocyanidin can prevent generating ahead of time for wrinkle of skin, can more supplement The free radical that nutrition and elimination are harmful in vivo, can prevent ultraviolet damage skin, can inhibit the activity of tyrosinase in skin； Pigment can be made to fade, whiteness of skin by the adjacent benzene diquinone construction recovery of melanin into phenolic structure；It can inhibit because of protein amino The Maillard reaction occurred with nucleic acid amino, so as to inhibit the formation of lipofuscin, senile plaque；Can with vitamin C or vitamin E it Between the effect of playing synergistic effect, playing beautifying face and moistering lotion.4. the anthocyanidin in lycium ruthenicum, which has, removes free radical harmful in vivo Effect, free radical are the one of the major reasons for causing aging and many diseases.And anthocyanidin can keep and enhance vitamin existing Activity in human body is the synergist of vitamin.Lycium ruthenicum anthocyanidin category small molecule, water-soluble substances, peroral dosage form, Yi Beiren Body quickly absorbs, and each histoorgan of human body can be rapidly entered, and bioavilability is good after 30 minutes oral, to connective group It is strong to knit affinity, stablizes under acidic environment, long half time, it is efficacy lasting up to 27 hours.Exempt from 5. human body is adjusted in anthocyanidin Epidemic disease power, builds up health, and improves sleep：Anthocyanidin has the function of that cell membrane is protected by free-radical oxidation, not have strength antioxygen Change and antianaphylaxis function, can pass through blood-brain barrier, cranial nerve can be protected not oxidized, can stablize cerebral tissue function, protect brain It is not injured by harmful chemical and toxin.6. the anthocyanidin in lycium ruthenicum has the effect of reinforcing blood vessel, improving cycle, flower Green element can improve blood circulation, restore the capilary effect lost, strengthen fragile blood vessel, thus make blood vessel more elastic； Anthocyanidin can effectively mitigate the symptoms such as pain, edema, night spasm.

Hei Maka：Agate card is a kind of crucifer for originating in South America, and leaf is oval, rhizome likeness in form turnip radish, can It is edible, it is a kind of natural food, nutrition is enriched, and the hypocotyl of agate card may be in golden or faint yellow, red, purple Color, blue, black or green.It is also kind the most rare that Hei Maka, which is that nutrition is most abundant in agate card,.In the dry roots of Hei Maka Chemical composition composition in protein content be more than 10%, the fiber also with 59% carbohydrate and 8.5%, and interior Containing minerals such as abundant zinc, calcium, iron, titanium, rubidium, potassium, sodium, copper, manganese, magnesium, strontium, phosphorus, iodine, and contain vitamin C, B₁、B₂、B₆、 A、E、B₁₂、B₅, unrighted acid, for the content of linoleic acid plus linolenic acid more than 53%, natural activity composition includes alkaloid, mustard Seed oil glycosides and its decomposition product benzyl isothiocyanate, sterol, polyphenols etc..

Hei Maka includes following aspects the main function that male keeps fit and healthy：It is 1. antifatigue：Hei Maka is containing higher The iron of amount, the ingredients such as protein, amino acid, minerals zinc, taurine can be significantly to antifatigue, and enhancing muscular endurance resists fortune Dynamic fatigue, helps firm immune system, promotes body's resistance to disease, and to antifatigue, enhancing energy, muscle power improve Anemia, The colour of skin is made to seem younger, energy is more sufficient.2. increase sperm quality：Nutriment in natural herbs can be effective It improves sperm quantity and enlivens ability, man is made to ejaculate strong and powerful, range is farther, powerful raising man's sexuality.3. it supplements Muscle power：Hei Maka can regain one's strength of body rapidly dispelling fatigue, regain one's vigor, and be a kind of qualified quick body by drug abuse test Power reinforcing agent.4. improve impotence and premature ejaculation：Abundant gal4 amino acid, polysaccharide, minerals and its exclusive bioactive substance Lepidium meyenii Walp/Maca alkene, Lepidium meyenii Walp/Maca amide, can effectively shorten the reaction time, rapid to erect, and improve erection hardness, thoroughly improve impotence and premature ejaculation disease Shape.5. improve sleep：Hei Maka can effectively improve anxiety and neurasthenia etc. caused by pressure, and Hei Maka is to eliminate anxiety Natural herbal and improve insomnia and dreamful sleep symptom good merchantable brand.6. a variety of alkaloids of Hei Maka can adjust adrenal gland, balanced body Interior hormone level, abundant taurine, protein etc. can improve and repair physiological function.7. it actively gives birth to：Promote sperm Increase and vigor with ovum, help to become pregnant, and stimulate reproductive organs, reactivity ability.8. enhancing memory：Black agate card have make head Brain is regained consciousness flexibly, improves working efficiency, and student improves in study, and person in middle and old age's memory capability is kept, and makes one clearheaded, clear thinking Effect.

Herba Cistanches：The fleshy stem of Herba Cistanches is containing Cistanoside A, B, C, H, Syring vulgaris phenol glucoside, 2- acetyl group Syring vulgaris phenol glucosides With echinacosid totally seven kinds of benzyl carbinol glucoside ingredients；Also glucoside containing Liriodendron, 8- table vomiting nuts glucoside acid, Daucosterol, glycine betaine, β-paddy steroid Alcohol, mannitol, n,N-Dimethylglycine methyl esters and phenylalanine, valine, leucine, isoleucine, lysine, Soviet Union's ammonia Acid, etc. 15 kinds of amino acid and succinic acid；Also comprising plurality kinds of health care substances such as triacontanol and polysaccharides.

The pharmacological action of Herba Cistanches is mainly by following several respects：1. anti-aging effects, 2. adjust endocrine, promote metabolism and 3. strong effect adjusts immune system and 4. promotes Synthesis of DNA.

Cordyceps sinensis：Cordyceps sinensis is the traditional rare medicated nourishing product in China, its flat property and sweet taste has tonifying lung kidney, stops Cough, benefit is deficient, supports the function of vital essence, has and supports lung yin, and kidney-replenishing, relieving cough and reducing sputum, anticancer prevent the effect of old, for flat tonifying yin sun Product, it is all without being avoided.

Extract present invention preferably uses cordyceps sinensis is, it is preferable to use cordycepin, more preferably 95% cordycepin.Worm Careless element is (especially ucleosides) main active in cordyceps sinensis and Cordyceps militaris, is a kind of natural drug, has The same negative and positive of cordyceps sinensis are the same as the function of mending with bidirectional modulation total balance of the body in traditional Chinese medical science medical knowledge.Cordycepin is in protect liver, guarantor's kidney, profit Lung aspect ingredient is purer, effect is more preferable, and strongly invigorating QI and blood, can eliminate present incurable dysmenorrhoea, migraine, cervical vertebra hyperplasia Etc. diseases.It is new old with antitumor, anti-aging, antibacterial, antiviral, immunological regulation, improvement from cordycepin in terms of doctor trained in Western medicine medical knowledge angle The multiple pharmacological effects such as free radical are removed in metabolism.

Cortex Eucommiae：It is warm-natured, micro-pungent sweet in flavor, can filling liver kidney, strengthening the bones and muscles, to caused by kidney deficiency spinal column ache, sufficient knee is weak and feeble, Habitual aborter caused by children's kidney deficiency, two crural paralysis and women's deficiency of the kidney, it is most appropriate.

Ganoderma lucidum：It is sweet in flavor, it is warm-natured, enter the heart, spleen, kidney, lung four and pass through.With anti-cancer and cancer-preventing, liver detoxification, hypoglycemic, the prevention heart The effects that angiosis, anti-hyperlipidemia, apoplexy, anti-aging and improvement neurasthenia.

Cynomorium songaricum：Cure mainly impotence and premature ejaculation, the moon decline the weak deficiency of Yin of dragon's blood, gas, dry feces, frequent urination, blood urine, it is dripping not to the utmost, Soreness and weakness of waist and knees, fatigue and weak, insomnia forgetfulness, the early white and hydrochloric acid in gastric juice ulcer of alopecia etc..Cynomorium songaricum can promote human body cell regeneration and new Old metabolism enhances immunoregulation capability, has apparent anti-cancer, antiviral and delaying senility function.

Lycium ruthenicum, Hei Maka, Herba Cistanches, cordyceps sinensis, Cortex Eucommiae, ganoderma lucidum and cynomorium songaricum belong to warm property medicinal material, are compounded Using easily there is the symptom got angry, therefore again hot to control with American Ginseng, lotus seeds, snow chrysanthemum and hawthorn in this formula, so as to reach It is mended to flat profit is flat, prevents the big dry effect of big heat.

Lotus seeds：Mild-natured, sweet-puckery flavor enters the heart, spleen, kidney channel；Tonifying spleen and stopping diarrhea, kidney-nourishing is puckery clear, mental-tranquilization.It is long for spleen deficiency It rushes down, under seminal emission band, palpitation and insomnia.Cure mainly night sleep dreaminess, insomnia, forgetful, restlessness and thirst, pain in the back flaccidity of lower limbs, dysfunction of vision and hearing, seminal emission, Stranguria with turbid discharge, protracted dysentery, void rush down under woman uterine bleeding band and the illnesss such as stomach void loss of appetite.Alkaloid contained by lotus seeds has significant strong The heart acts on, energy clearing away the heart-fire, has brain tonic, enhancing memory, the advantageous effect for improving working efficiency.

Snow chrysanthemum：Flavonoid substances, a variety of mineral elements needed by human, more than 20 kinds of amino acid, number there are many containing in snow chrysanthemum Ten kinds of aromatic compounds, abundant organic acid, vitamin, enzyme and polysaccharide etc. have the pharmacological effect more than general jasmine tea. Snow chrysanthemum has clearing heat and detoxicating, promoting blood circulation and removing blood stasis, strengthening the spleen and stomach, lowering blood pressure and blood fat and hypoglycemic work(, can also control nervous, stomach and intestine not Suitable, loss of appetite, dysentery and pyogenic infections.There is stronger inhibiting effect to glucosidase activity, diabetes can be prevented.Simultaneously Snow chrysanthemum can also prevent the generation of degeneration, aging and the canceration of cell.Through research, n-butanol extract, the oil of coreopsis tinctoria Ether extract, chloroform extract have conditioning blood of human body microcirculation, and vasodilator effect has apparent drop for hypertension Pressure acts on.

Hawthorn：Containing multivitamin, tartaric acid, citric acid, crataegolic acid, malic acid etc., also containing flavonoids, lactone, sugar The minerals such as class, protein, fat and calcium, phosphorus, iron, contained lipolytic enzyme can promote the digestion of fat food.Digestion can be controlled Bad and coronary heart disease because of flavonoids energy coronary artery dilator, increase blood flow coronarius contained by hawthorn, promotes gastric secretion With the functions such as enzyme element in increase stomach.The traditional Chinese medical science thinks, hawthorn has stagnant disperse accumulationization, convergence and dysentery, activates blood circulation and disperses blood clots and other effects, cures mainly drink The diseases such as dyspepsia is stagnant, chest diaphragm feeling of fullness, hernia blood stasis amenorrhoea.Containing drug ingedients such as mountain terpene and flavonoids in hawthorn, have notable Expansion blood vessel and antihypertensive effect, have enhancing cardiac muscle, arrhythmia, adjusting blood fat and cholesterol level function.

American Ginseng：American Ginseng is also known as American ginseng, is a kind of mend without high-class healthy product dry, sutable for men, women, and children, main product In north americas such as the U.S., Canada.It is with work(such as benefiting qi and nourishing blood, enriching yin and nourishing kidney, strengthening spleen and nourishing stomach, anti-aging and beauty treatments Effect.American Ginseng tonifying Qi, it is cool in nature, it will not get angry after taking, the people of deficiency of both qi and yin is especially suitable.

Red matrimony vine：It is mild-natured, it is sweet in flavor, there is tonifying kidney and nourishing liver, benefiting shrewd head, strengthen the bone, except pain in the back, long term usage can prolong life Function.The especially people of person in middle and old age's kidney deficiency, food most preferably.

Honey：Honey, which has, improves looks, improves immunity, liver protection moistening lung, antifatigue, improvement sleep, invigorating stomach and relaxing bowels, rush Into skin tissue regeneration and other effects, taken for a long time suitable for a middle-aged person.Present invention preferably uses medlar nectar, medlar nectar is honeybee Acquisition medlar nectar is made, the traditional healthy nutritive value of the existing honey of medlar nectar, more because it is the essence of matrimony vine, tool Have nourishing liver and kidney, benefiting shrewd head, nourishing and strengthening Yin and Yang, moisten the lung and relieve the cough tonifying Qi the effect of.Vim and vigour two is suitble to lose, hypertension, have a delicate constitution, Personage's clothes of hepatosis etc. caused by visual impairment, anaemia, chronic hepatitis, Poisoning or metabolism hepatopathy and biliary system With.It is particularly adapted to lumbago due to the kidney deficiency, emission and spermatorrhea, busy male eat.

In some preferred embodiments of the present invention, raw material used have the unique place of production to require.Lycium ruthenicum, Hei Maka, Herba Cistanches, red matrimony vine preferably originate from Chaidamu Basin, Qinghai Province, have Qinghai lycium ruthenicum original producton location, pollution-free, anthocyanidin Content it is high wait the characteristics of.Snow chrysanthemum preferably uses Xinjiang and the Qinghai place of production.

The compounding principle of composition provided by the invention is as follows：

The anti-oxidant of lycium ruthenicum is taken, anti-aging, nourishing Yin and keeping spirit, calmness, beauty and skin care is moisturized, removes human free radical, adjusts Section body immunity, build up health, keep fit and healthy, loins-strengthening and kidney-invigorating, building up health, improves sleep, soften blood vessel, improvement human body it is micro- Cycle, protect eyes, beautifying skin and dispel blackspot and other effects；Take the strong constitutions of Hei Maka, it is antifatigue and treatment male Impotence and premature ejaculation improves the effect of male's sexual, enhancing male fertility and fecundity；Take Herba Cistanches kidney-replenishing, benefiting essence-blood, profit Enteron aisle, the effect of strengthening the bone；It is good for again with traditional nourishing liver and kidney, benefiting shrewd head such as red matrimony vine, Cortex Eucommiae, cordyceps sinensis, cynomorium songaricum, strengthening tendons Body, the male health-care good medicine of tonifying Qi and blood are compatible, so as to reach anti-aging, strengthen immunity, anti-cancer and cancer-preventing, blood-nourishing, benefit The effect of liver kidney, strengthening the bones and muscles and strengthening the essence gas, so as to prevent impotence premature ejaculation, the moon declines dragon's blood, soreness and weakness of waist and knees, fatigue and weak, fear The all diseases of deficiency of the kidney caused by the insufficiencies of the kidney yang such as cold all cold, limbs pain, insomnia forgetfulness, alopecia be early white strengthen the main work(of kidney tonifying Energy.American Ginseng is taken to equal benefit function, boosting qi and nourishing yin, clearing heat and promoting fluid function simultaneously；It is ganoderma lucidum anti-cancer and cancer-preventing, liver detoxification, hypoglycemic, anti- The effects that angiocardiopathy, anti-hyperlipidemia, apoplexy, improvement neurasthenia；With lotus seeds tonifying spleen and stopping diarrhea, kidney-nourishing is puckery clear, mental-tranquilization； It is clearing heat and detoxicating, promoting blood circulation and removing blood stasis with snow chrysanthemum, strengthening the spleen and stomach, lowering blood pressure and blood fat and hypoglycemic；With hawthorn disperse accumulationization it is stagnant, enhancing cardiac muscle, Arrhythmia adjusts blood fat and cholesterol level, heat-clearing toxin expelling and resolving stagnation for tranquilization.Entire formula is just around this core of kidney tonifying The heart has good cleaning free radical and human toxin, anti-oxidant, anti-aging, strengthen immunity, warming and invigorating kidney Yang, enhancing male The remarkable efficacy of sexual function, have concurrently protecting and nourishing liver, boosting qi and nourishing yin, adjust mood, conditioning endocrine, reduce blood-fat and blood sugar blood pressure, The effect of heat-clearing toxin expelling and resolving stagnation for tranquilization, can be effectively prevented and treated modern workplace male deficiency of the kidney and inferior health problem.It is above whole The collocation of a formula is scientific and reasonable, this formula will pass through the change of different prescriptions and dispensing size with the common compatibility of (food) object of adding medicine to Change, constituting one has innovative formula invention.

This formula and prescription science, consumption proportion are accurate.Enough lycium ruthenicum anthocyanidin can remove human free radical in side, The antioxidant effect of body is improved, enhances body immunity.Enter kidney again with Hei Maka, Herba Cistanches, with red matrimony vine, Cortex Eucommiae, cordyceps sinensis Element, cynomorium songaricum etc. are nourishing liver and kidney, benefiting shrewd head, strengthening tendons are healthy and strong, tonifying Qi and blood, so as to enhance kidney tonifying and Yang-strengthening effect.To prevent Entire formula is too hot, and the pharmacological property of " clear " " drop " " flat " of lotus seeds, chrysanthemum, American Ginseng is taken to carry out the heat of conditioning balance prescription Property, make entirely to be formulated flat and slightly warm, help, conditioning and clearing function lay equal stress on, have benefit to have clearly, based on temperature compensation, be well suited for China Male's physique characteristic is suitble to take for a long time.

In an optional embodiment, the composition that kidney is good in the establishing-Yang is further included in Radix Notoginseng, ginseng and wilsonii It is one or more；Optionally, the composition includes Radix Notoginseng 5-15 parts by weight, for example, can be but be not limited to 5,7,10, 12 or 15 parts by weight, preferably include 9-11 parts by weight；Optionally, the composition includes ginseng 2-10 parts by weight, such as can Think but be not limited to 2,5,7 or 10 parts by weight, preferably include 5-8 parts by weight；Optionally, the composition includes wilsonii 5-20 parts by weight, such as can be but be not limited to 5,8,10,12,15,18 or 20 parts by weight, preferably include 9-12 weight Part.

Wherein, Radix Notoginseng, ginseng and wilsonii have effects that as follows：

Radix Notoginseng：Sweet, slight bitter, temperature；Return liver, stomach；With dissipate stasis of blood hemostasis, the effect of detumescence ding-tong；For spitting blood, haematemesis, Bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.

Ginseng：Sweet, slight bitter, tepor；Returns spleen, lung, the heart, kidney channel；With reinforcing vital energy, veins takes off admittedly reinforces the spleen to benefit the lung, and promotes the production of body fluid The effect of blood-nourishing, tranquilize the mind and promote the intelligence.It to be taken off for physically weak, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, injury thirst, and interior heat disappears Yearningly, deficiency of qi and blood, prolonged illness void is thin, insomnia of palpitating with fear, impotence Gong Leng.

Wilsonii：Wilsonii contains a variety of glucosides, and which part glucoside has similar physiological activity to panaxoside, has antifatigue Effect, be drink beneficial health drink.Modern pharmacological research confirms that wilsonii is containing there are many acanthoside, polysaccharide isoreactivities Ingredient, have anti-aging, antifatigue, anticancer and adjust nerve, endocrine, cardiovascular function, raising body to physics, chemistry, The pharmacological actions such as harmful resistivity irritated such as biology.In neurasthenia, insomnia, high blood pressure, coronary heart disease, cerebral infarction, brain The treatment of the illness such as artery sclerosis, climacteric syndrome, dyslipidemia, diabetes, rheumatism, chronic bronchitis and tumour In, there is certain curative effect.Radix Acanthopanacis senticosi tea can enhance immune function, increase blood flow, improve the blood supply state of the heart, brain, also adjust The effect of whole blood pressure.Also there is good therapeutic effect to diseases such as hypogona dism, impotence and premature ejaculation.

The present invention provides a kind of purposes of above-mentioned composition in health products and drug are prepared, the purposes for example can be with For but be not limited to antifatigue, anti-oxidant and establishing-Yang and be good for kidney.Above-mentioned composition, which can be applied to prepare, alleviates each of male's inferior health Kind health products or drug, can prepare the health products of the diversified forms such as health liquor, health care oral liquid, can be used for preparing ball The Chinese patent drug of the diversified forms such as agent, paste or tablet.

The present invention also provides a kind of oral liquid, the raw material of the oral liquid includes above-mentioned composition, has above-mentioned composition Whole health-care effects, it is convenient also to have the advantages that drink.

In certain embodiments of the present invention, the raw material includes carrying for raw slurry, the soak of raw material and raw material Take one or more of object.

In certain embodiments of the present invention, the raw material includes raw slurry, in an optional embodiment, Raw slurry is squeezed the juice the raw slurry of obtained each component independence by the dry product of each component after soaking, optionally, uses juice extractor Or juicer prepares the slurries of each component.In a preferred embodiment party, each component dry product is prepared as follows To raw slurry：

(a) it crushes and impregnates：The dry product of each component is first sliced, is then crushed to after 25-60 mesh and adds 5-10 times of body again Long-pending water impregnates, wherein, Hei Maka, Herba Cistanches, cynomorium songaricum and American Ginseng are preferably crushed to 40-50 mesh, then add in 6-10 times of body Long-pending pure water impregnates 5-10 hours；Lycium ruthenicum dry product, red matrimony vine dry product, snow chrysanthemum, Cortex Eucommiae, lotus seeds and hawthorn are preferably crushed to 25-40 mesh, the pure water for then adding in 6-10 times of volume impregnate 3-5 hours；Each component preferably impregnates in pure water.

(b) it squeezes the juice：Each component after immersion is subjected to mashing processing, is then squeezed the juice, the slurries 80-120 after squeezing the juice Purpose strainer detaches slurries and residue, and the step of preferably detaching slurries with residue operation 2-4 times all squeezes active principle Totally.

(c) it centrifuges：Slurries after separation residue under conditions of 3000-4000r/min are centrifuged, are detached in slurries Suspension screenings, preferably centrifuged in horizontal centrifuge.

(d) it deaerates：The slurries of separator well are deaerated with degasser, degasser vacuum degree 0.08-0.10Mpa, degassing time 2-10min, to slough the bubble in slurries；Then clarification 1-2h is stood under conditions of 20-50 DEG C.

(e) start to filter for 35-40 DEG C in temperature with filter, reflux and filter liquid 5-15min collects clear filtrate, obtains To clear slurries；

(f) clear slurries are sterilized through ultra high temperature short time sterilization machine, 95-105 DEG C of sterilising temp, time 8-15s；Sterilizing The slurries crossed are put to temporary storage tank rapid cooling to 50 DEG C, are concentrated；

(g) it is concentrated under the conditions of vacuum degree 0.08-0.12Mpa, 45-60 DEG C of temperature and steam pressure 0.15-0.5Mpa, it is dense Soluble solid is reduced to up to 40%-50%, then 25-35 DEG C is water-cooled to condensation in drainer, obtains each component Raw slurry.

Optionally, the raw slurry of above-mentioned each component is made in advance, constant temperature is cold under conditions of being subsequently placed in -18~-25 DEG C It hides.

In the present embodiment, each component is soaked in for example can be but be not limited to pure water, distilled water or ore deposit It in spring, can also be soaked in pharmaceutically or in the acceptable solvent of field of food, the present invention, which does not also limit addition, can both promote The additive of pharmacological property is soaked and not destroyed into the bulk pharmaceutical chemicals acceleration under dry product state.

In certain embodiments of the present invention, it is also an option that using enzymolysis or other can obtain the slurries of each component Method prepare raw slurry.

In certain embodiments of the present invention, using the fresh fruit of lycium ruthenicum and red matrimony vine through obtained raw slurry of squeezing the juice, Implementation is as follows：It is selected it is clean, without it is mouldy, without going bad, without agriculture is residual, fruit is big, maturity is high lycium ruthenicum fresh fruit and Red medlar fresh fruit, preferably August originate from the fresh fruit in Qinghai Province's Hai Xizhou promises wood flood area, pass through manual sorting and removal of impurities, pure water It is put into beater after cleaning to be fully beaten, is then filtered with the strainer of 60-100 mesh, removes pericarp, seed, handle, it will 100% full juice retains the raw slurry up to lycium ruthenicum fresh fruit and red medlar fresh fruit.

In certain embodiments of the present invention, the raw material includes the soak of each raw material, optionally implements at some In mode, the soak includes each component being soaked in solvent, and the solvent is pharmaceutically or field of food is acceptable Solvent, optionally, the solvent for example can be, but not limited to as pure water, mineral water or distilled water.In some of the present invention In embodiment, the raw material can also include the extract of each component.

The present invention also provides a kind of preparation method of above-mentioned oral liquid, the preparation method include by each raw material according to The step of side's amount mixing, such as can be but be not limited to that mode is implemented as follows：Optionally, the powder of each raw material and raw material are starched It is filtered after liquid mixing and oral liquid is made, each raw material is preferably crushed to 80-200 mesh, more preferably 100-120 mesh；Optionally, will Oral liquid is made after being mixed according to formula ratio in the raw slurry of each raw material；Optionally, by the extract of each raw material according to formula ratio It is soaked in after mixing after being filtered in solvent and oral liquid is made；Optionally, by the extract of raw material and raw slurry according to formula ratio Oral liquid is made after mixing.The preparation method of above-mentioned oral liquid provided by the invention, the good health care for remaining bulk pharmaceutical chemicals and Therapeutic effect, and it is suitble to large-scale production, there is great industrial value.

In some optional embodiments of the present invention, above-mentioned oral liquid is prepared as follows to obtain：

(a) by lycium ruthenicum, Hei Maka, Herba Cistanches, Cortex Eucommiae, ganoderma lucidum, cynomorium songaricum, lotus seeds, snow chrysanthemum, hawthorn, American Ginseng and red Chinese holly The raw slurry of Qi is mixed according to formula ratio.

(b) ganoderma lucidum is crushed to 100-120 mesh.

(c) ganoderma powder, cordycepin and honey are added according to formula ratio in the raw slurry mixed in step (a).

(d) it is seasoned using flavoring agent, any flavoring agent for allowing to eat and do not influence function of the present invention can be selected, Optimization citric acid and sucrose are as flavoring agent.

(e) it is filtered under the conditions of filter sizes 2-5um, 0.15-0.5Mpa with Membrane filtering machine.

(f) under conditions of 95-105 DEG C of temperature condition high-temperature short-time sterilization 10-20s to get above-mentioned oral liquid.

In some optional embodiments of the present invention, above-mentioned oral liquid can also be prepared as follows to obtain： The extract of each component and honey are mixed to add in into distilled water according to formula ratio and adequately stirred, then add sucrose, lemon Lemon acid is seasoned.Then it is filtered under conditions of filter sizes 2-5um with Membrane filtering machine；In 95-105 DEG C of temperature, sterilizing 10- It is filling after 20s, sterile filling is carried out with 50mg/ bottles of specification, compound oral liquid product is obtained after detection is qualified.

The advantageous effect further illustrated the present invention with reference to preferred embodiment：

Embodiment 1

A kind of composition is present embodiments provided, the component of the composition is dry product, and meter is comprising such as in parts by weight Lower component：30 parts of lycium ruthenicum, 10 parts of black agate card, 10 parts of Herba Cistanches, 8 parts of cordyceps sinensis, 15 parts of Cortex Eucommiae, 8 parts of ganoderma lucidum, cynomorium songaricum 10 Part, 8 parts of lotus seeds, 5 parts of snow chrysanthemum, 10 parts of hawthorn, 8 parts of American Ginseng, 20 parts of red matrimony vine, 10 parts of honey, 10 parts of Radix Notoginseng, 6 parts of ginseng and 15 parts of wilsonii.

Embodiment 2

A kind of composition is present embodiments provided, the component of the composition is dry product, and meter is comprising such as in parts by weight Lower component：25 parts of lycium ruthenicum, 55 parts of black agate card, 20 parts of Herba Cistanches, 5 parts of cordyceps sinensis, 20 parts of Cortex Eucommiae, 5 parts of ganoderma lucidum, cynomorium songaricum 15 15 parts of part, 5 parts of lotus seeds, 10 parts of snow chrysanthemum, 5 parts of hawthorn, 15 parts of American Ginseng, 15 parts of red matrimony vine, 15 parts of honey and Radix Notoginseng.

Embodiment 3

A kind of composition is present embodiments provided, the component of the composition is dry product, and meter is comprising such as in parts by weight Lower component：50 parts of lycium ruthenicum, 5 parts of black agate card, 5 parts of Herba Cistanches, 15 parts of cordyceps sinensis, 10 parts of Cortex Eucommiae, 10 parts of ganoderma lucidum, 5 parts of cynomorium songaricum, 10 parts of 10 parts of lotus seeds, 2 parts of snow chrysanthemum, 15 parts of hawthorn, 5 parts of American Ginseng, 45 parts of red matrimony vine, 5 parts of honey, 5 parts of wilsonii and ginseng.

Embodiment 4

A kind of composition is present embodiments provided, the component of the composition is dry product, and meter is comprising such as in parts by weight Lower component：25 parts of lycium ruthenicum, 30 parts of black agate card, 6 parts of Herba Cistanches, 15 parts of cordyceps sinensis, 6 parts of Cortex Eucommiae, 18 parts of ganoderma lucidum, 7 parts of cynomorium songaricum, 2 parts of 9 parts of lotus seeds, 3 parts of snow chrysanthemum, 12 parts of hawthorn, 12 parts of American Ginseng, 15 parts of red matrimony vine, 12 parts of honey and ginseng.

Embodiment 5

A kind of composition is present embodiments provided, the component of the composition is dry product, and meter is comprising such as in parts by weight Lower component：40 parts of lycium ruthenicum, 8 parts of black agate card, 15 parts of Herba Cistanches, 6 parts of cordyceps sinensis, 10 parts of Cortex Eucommiae, 12 parts of ganoderma lucidum, cynomorium songaricum 12 12 parts of part, 6 parts of lotus seeds, 8 parts of snow chrysanthemum, 8 parts of hawthorn, 6 parts of American Ginseng, 35 parts of red matrimony vine, 8 parts of honey, 2 parts of ginseng and Radix Notoginseng.

Embodiment 6

A kind of oral liquid and preparation method thereof is present embodiments provided, the raw material that the present embodiment uses is as follows：This example is former Material removes medlar nectar all using first-class dried food and nuts raw material available on the market, including selected Qinghai lycium ruthenicum dry product, plateau Produce Hei Maka, desert Herba Cistanches, Cortex Eucommiae, 95% cordycepin, ganoderma lucidum, cynomorium songaricum, American Ginseng, the red matrimony vine in Qinghai, Xinjiang snow chrysanthemum, lotus Son, hawthorn, medlar nectar, Radix Notoginseng, ginseng and wilsonii.Careful sorting is carried out to all Yi Shang raw materials, pest and disease damage is sorted out, rots Raw material, all kinds of impurity are removed, select without go bad, clean raw material for standby.

The preparation method of the present embodiment is as follows, and technological process is as shown in Figure 1：

(a) it crushes and impregnates：Hei Maka, Herba Cistanches, cynomorium songaricum, four taste raw material of American Ginseng are first sliced, then broken It is crushed on machine with the sieve of 50 mesh, the pure water for then adding 8 times of volumes or so carries out the immersion of 6 hours or so；It is right 30 purposes are first pressed on crusher in lycium ruthenicum, red matrimony vine, Xinjiang snow chrysanthemum, Cortex Eucommiae, lotus seeds, hawthorn, Radix Notoginseng, ginseng and wilsonii Sieve is crushed, and is then respectively adding the immersion that 8 times of volume pure water carry out 4 hours or so.

(b) it squeezes the juice：Each component after immersion is subjected to mashing processing, is then squeezed the juice, by 100 purposes of the slurries after squeezing the juice Strainer detaches slurries and residue, and the step of slurries are detached with residue operates 2 times, active principle is all squeezed totally.

(c) it centrifuges：By the slurries after separation residue using horizontal centrifuge under conditions of 3000-4000r/min Centrifugation detaches the suspension screenings in slurries.

(d) it deaerates：The slurries of separator well are deaerated with degasser, degasser vacuum degree 0.095Mpa, degassing time 5min, To slough the bubble in slurries；Then clarification 2h is stood under conditions of 40 DEG C.

(e) start to filter for 35-40 DEG C in temperature with filter, reflux and filter liquid 10min collects clear filtrate, obtains Clear slurries.

(f) it sterilizes, cool down：Clear slurries are sterilized through ultra high temperature short time sterilization machine, 95-105 DEG C of sterilising temp, the time 10s；The slurries to sterilize are put to temporary storage tank rapid cooling to 50 DEG C, are concentrated.

(g) it concentrates：In vacuum degree 0.096-0.099Mpa, 50-55 DEG C of temperature and steam pressure 0.196-0.294Mpa items It is concentrated under part, is concentrated into soluble solid up to 45%, is then water-cooled to 30 DEG C with condensation in drainer, obtains each component Raw slurry.

(h) ganoderma lucidum is crushed with the pulverizer of 100 mesh spare.

(i) 2 times of weight are added after the raw slurry of each component made from above-mentioned steps is mixed according to following formula ratio The pure water of part：30 parts of lycium ruthenicum, 10 parts of black agate card, 10 parts of Herba Cistanches, 15 parts of Cortex Eucommiae, 8 parts of ganoderma lucidum, 10 parts of cynomorium songaricum, lotus seeds 8 15 parts of part, 5 parts of snow chrysanthemum, 10 parts of hawthorn, 8 parts of American Ginseng, 20 parts of red matrimony vine, 10 parts of Radix Notoginseng and wilsonii.

(j) 10 parts of 8 parts of ganoderma powder, 8 parts of cordycepin and medlar nectar are added in above-mentioned mixed liquor, lemon is added in after mixing Lemon acid and sucrose seasoning.

(k) secondary filter：It is filtered under the conditions of filter sizes 3um, 0.2Mpa with Membrane filtering machine.

(l) two-stage sterilization：Finally in second 100 DEG C of temperature, progress of 10-20s high-temperature short-time sterilization.

(m) sterile filling is carried out with 50mL/ bottles of specification, oral liquid product is obtained after detection is qualified.

Embodiment 7

A kind of oral liquid and preparation method thereof is present embodiments provided, the raw material that the present embodiment uses is as follows：Lycium ruthenicum and Red matrimony vine carries out mashing using fresh picking fruit and squeezes, and remains the active ingredient in red-black matrimony vine, black Chinese holly to greatest extent Qi and red matrimony vine be selected from August originate in Qinghai Province's Hai Xizhou promises wood flood area it is selected it is clean, without it is mouldy, do not go bad, do not have The fresh fruit that agriculture is residual, fruit is big, maturity is high；The original Hei Maka of height, desert Herba Cistanches, Cortex Eucommiae, ganoderma lucidum, cynomorium songaricum, American Ginseng, Xinjiang snow Chrysanthemum, lotus seeds, hawthorn, Radix Notoginseng, ginseng and wilsonii are dry product.

The preparation method of the present embodiment is as follows：

(a) raw slurry of lycium ruthenicum and red matrimony vine is made as follows：Cleaned by manual sorting, pure water it is clear It squeezes the juice after washing, is then filtered with the strainer of 100 mesh, slags detach by fruit seed, pericarp, fruit be bright etc., separating step operation Twice, 100% full juice is retained, as raw slurry.

(b) other dried food and nuts raw materials are crushed to after 60 mesh to be soaked in impregnate in the water of 8 times of volumes and are squeezed the juice afterwards for 24 hours, Ran Houyong 100 mesh filter screens detach juicing with raw material residue, and separation is twice.

Step (c)-(m) is the same as embodiment 6.

Embodiment 8

A kind of oral liquid and preparation method thereof is present embodiments provided, the raw material that the present embodiment uses is as follows：By weight Number meter includes：25% 30 parts of lycium ruthenicum extract, 10 parts of Hei Maka extracts, 10 parts of 50% cistanche extracts, 50% Cortex Eucommiae 15 parts of extract, 8 parts of 50% Ganodenna Lucidum P.E, 10 parts of 50% Herba Cynomorii extract, 8 parts of 50% American ginseng extract, 50% red Chinese holly 20 parts of Qi extract, 5 parts of 50% coreopsis tinctoria extract, 8 parts of 50% Semen Nelumbinis extract, 10 parts of 50% haw thorn extract, medlar nectar 10 parts, 95% 8 parts of cordycepin.More than raw extract is marketable material.

The preparation method of the present embodiment is as follows：

After the mixing of more than raw material, the sterile distilled water of raw material gross weight 2 times of parts by weight of number is added in, is fully stirred, Again plus sucrose, citric acid are seasoned.Then it is filtered under conditions of filter sizes 3um with Membrane filtering machine；105 DEG C of temperature, It is filling after sterilizing 10s, sterile filling is carried out with 50mmL/ bottles of specification.Oral liquid product is obtained after detection is qualified.

Comparative example 1

This comparative example provides a kind of oral liquid and preparation method thereof, and difference lies in preparation process with embodiment 6 (i) and in (j), each raw material is mixed by following parts by weight：15 parts of lycium ruthenicum, 60 parts of black agate card, 25 parts of Herba Cistanches, cordyceps sinensis 1 part, 25 parts of Cortex Eucommiae, 1 part of ganoderma lucidum, 20 parts of cynomorium songaricum, 2 parts of lotus seeds, 15 parts of snow chrysanthemum, 2 parts of hawthorn, 20 parts of American Ginseng, 10 parts of red matrimony vine, 20 parts of 25 parts of honey and Radix Notoginseng.

Comparative example 2

This comparative example provides a kind of oral liquid and preparation method thereof, and difference lies in preparation process with embodiment 6 (i) and in (j), each raw material is mixed by following parts by weight：60 parts of lycium ruthenicum, 2 parts of black agate card, 2 parts of Herba Cistanches, cordyceps sinensis 20 Part, 5 parts of Cortex Eucommiae, 20 parts of ganoderma lucidum, 2 parts of cynomorium songaricum, 15 parts of lotus seeds, 1 part of snow chrysanthemum, 25 parts of hawthorn, 2 parts of American Ginseng, 60 parts of red matrimony vine, bee 15 parts of 2 parts of honey, 2 parts of wilsonii and ginseng.

Comparative example 3

This comparative example provides a kind of oral liquid, and difference lies in without lycium ruthenicum with embodiment 6.

Comparative example 4

This comparative example provides a kind of oral liquid, and difference lies in without Hei Maka with embodiment 6.

Comparative example 5

This comparative example provides a kind of oral liquid, and difference lies in without Herba Cistanches with embodiment 6.

Comparative example 6

This comparative example provides a kind of oral liquid, and the raw material for differing only in the oral liquid with embodiment 6 is only comprising black Matrimony vine, Hei Maka and Herba Cistanches, the oral liquid are the mixed liquor of lycium ruthenicum, Hei Maka and the raw slurry of Herba Cistanches.

Comparative example 7

This comparative example provides a kind of oral liquid, does not include lotus with the raw material for differing only in the oral liquid of embodiment 6 Son, snow chrysanthemum and American Ginseng.

Comparative example 8

This comparative example provides a kind of oral liquid, does not include with the raw material for differing only in the oral liquid of embodiment 6 red Matrimony vine, Cortex Eucommiae, cordyceps sinensis and cynomorium songaricum.

The physical and chemical index for the oral liquid that embodiment 6-8 is provided is as follows：

Organoleptic indicator

Color and luster：Dark brown liquid；Flavour and smell：Sweetness slightly has bitterness, has peculiar fragrance and smell, it is dense to be diluted to Normal juice Without being charred taste, free from extraneous odour when spending；Tissue morphology：It is organized as dark brown uniform liquid, no layering, deposited phenomenon；Impurity：Without external Impurity.

2. physical and chemical index

Soluble solid 35% ± 1%；PH value 5.0-7.0.

3. microbiological indicator

Total number of bacteria≤3000/mL；Coliform, pathogenic bacteria are without detection.

Effect example 1

With reference to the Ministry of Public Health《Health food is examined and assessment technique specification》The side of function of physical fatigue alleviation in version in 2003 Method selects the mice burden swimming time to measure and is measured with hepatic glycogen content.

Male Kunming strain mice is selected, sets up test group 1-16 and blank control group, every group randomly selects 10, average body Decoction 0.5mL after the decoction of weight 19-22g, test group 1-5 difference gavage embodiment 1-5 compositions, test group 6-16 are filled respectively The oral liquid 0.5mL that stomach embodiment 6-8 and comparative example 1-8 is provided, the physiological saline of blank control group gavage equivalent.One time a day, Continuous gavage 30 days.

Loaned swimming test：Every group of 5 mouse are taken at random, by mouse tail heavy burden 5%, are placed in 40cm × 60cm × 40cm Pond went swimming, depth of water 30cm, record mouse swimming start to the death time as the mice burden swimming time.

Hepatic glycogen measures：Every group of residue mouse cervical dislocation is put to death into mouse, takes liver, is homogenized, is measured with anthrone method Hepatic glycogen content.The results are shown in table below：

As can be seen from the above table：The component formula of composition provided by the invention with establishing-Yang kidney strengthening effect can improve The average swim time of mouse and average hepatic glycogen amount, illustrate that the composition has the effect of good antifatigue, by embodiment It is reasonable that prescription compatibility provided by the invention is can be seen that with comparative example 3-8, and combining between species each component has synergistic effect；By Embodiment 6-8 can be seen that the composition is made oral liquid contributes to body to absorb drug effect；By embodiment 6 and comparative example 1-2 As can be seen that the antifatigue effect of formula ratio provided by the invention is optimal.

Effect example 2

The middle-aged male volunteer of 100 25-45 is randomly selected, is provided to volunteer oral in the embodiment of the present invention 6 Liquid, one time a day, each 50mL pay a return visit using effect after one month, wherein there is 82 volunteers to explicitly indicate that using the present invention's Feeling of fatigue mitigates after oral liquid, full of vitality；Sexual desire enhances, and sexual function significantly improves, and wherein model case is as follows：

Model case 1

Mr. Wang, male, 40 years old, certain small business senior executive, operating pressure was big, and due to the dinner party of normal phase and diet is irregular leads It causing fat fat, before the oral liquid for not drinking the present invention, often sense is short of physical strength, tired out, powerless carry out free life after daily work, and Since operating pressure leads to greatly slight blahs aypnia, irritability is easily hot-tempered, monthly 1 time or without sexual life.Take the oral liquid of the present invention Energetic afterwards, the non-working time also has energy to take exercise, and further alleviates the sub-health state of Mr. Wang, and sleeps Dormancy quality increases, and sexual desire enhancing, sexuality also increases.

Model case 2

Feng, man, 28 years old, company clerk, operating pressure was big, adhered to that sport is forged though having before not drinking oral liquid of the invention Refining, but feel to be short of physical strength often, easy cold perspiration in motion process, and sexuality is bad.Take the oral liquid of the present invention one week Energetic afterwards, although life stress does not subtract, depression and low is less prone to before oral liquid compared to taking for not cold perspiration again The state of mind, and sexuality significantly improves, and shows as the sexual life time and improves more than 50%.

Finally it should be noted that：The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent Pipe is described in detail the present invention with reference to foregoing embodiments, it will be understood by those of ordinary skill in the art that：Its according to Can so modify to the technical solution recorded in foregoing embodiments either to which part or all technical features into Row equivalent replacement；And these modifications or replacement, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution The range of scheme.

Claims (10)

1. the composition of kidney is good in a kind of establishing-Yang, which is characterized in that the composition is counted in parts by weight comprising following component：Black Chinese holly 25-250 parts of Qi, 5-55 parts of black agate card, 5-20 parts of Herba Cistanches, 5-15 parts of cordyceps sinensis, 10-20 parts of Cortex Eucommiae, 5-10 parts of ganoderma lucidum, lock It is 5-15 parts positive, 5-10 parts of lotus seeds, 2-10 parts of snow chrysanthemum, 5-15 parts of hawthorn, 5-15 parts of American Ginseng, matrimony vine 15-120 parts and honey 5- red 15 parts.

2. composition according to claim 1, which is characterized in that the lycium ruthenicum includes lycium ruthenicum dry product and/or black Chinese holly Qi fresh goods；And/or the red matrimony vine includes red matrimony vine dry product and/or red matrimony vine fresh goods；

Preferably, the composition includes lycium ruthenicum dry product 25-50 parts by weight, preferably 25-40 parts by weight, more preferably 25- 35 parts by weight；

Preferably, the composition includes lycium ruthenicum fresh goods 50-200 parts by weight, preferably 100-200 parts by weight, more preferably 150-200 parts by weight；

Preferably, the composition includes red matrimony vine dry product 15-45 parts by weight, preferably 15-35 parts by weight, more preferably 18- 25 parts by weight；

Preferably, the composition includes red matrimony vine fresh goods 45-75 parts by weight, preferably 50-65 parts by weight, more preferably 55- 65 parts by weight.

3. composition according to claim 1, which is characterized in that the composition further includes Radix Notoginseng, ginseng and wilsonii In it is one or more；

Preferably, the composition includes Radix Notoginseng 5-15 parts by weight, preferably 8-12 parts by weight, more preferably 9-11 parts by weight；

Preferably, the composition includes ginseng 2-10 parts by weight, preferably 4-9 parts by weight, more preferably 5-8 parts by weight；

Preferably, the composition includes wilsonii 5-20 parts by weight, preferably 8-15 parts by weight, more preferably 9-12 weight Part.

4. composition according to claim 1, which is characterized in that the honey includes medlar nectar.

5. according to the composition described in any one of claim 1-4, which is characterized in that the composition includes black agate card 8-30 Parts by weight, Herba Cistanches 6-15 parts by weight, cordyceps sinensis 6-10 parts by weight, Cortex Eucommiae 12-18 parts by weight, ganoderma lucidum 6-9 parts by weight, cynomorium songaricum 7-12 parts by weight, lotus seeds 6-9 parts by weight, snow chrysanthemum 3-8 parts by weight, hawthorn 8-12 parts by weight, American Ginseng 6-12 parts by weight and honey 8-12 parts by weight；

Preferably, the composition includes black agate card 8-15 parts by weight, Herba Cistanches 8-12 parts by weight, cordyceps sinensis 7-11 weight Part, Cortex Eucommiae 14-16 parts by weight, ganoderma lucidum 7-8 parts by weight, cynomorium songaricum 8-11 parts by weight, lotus seeds 7-9 parts by weight, snow chrysanthemum 4-6 parts by weight, 9-11 parts of hawthorn 9-11 parts by weight, American Ginseng 7-10 parts by weight and honey.

6. purposes of the composition described in a kind of any one of claim 1-5 in health products and drug are prepared, feature exist In the purposes is good for kidney including antifatigue, anti-oxidant and establishing-Yang.

7. a kind of oral liquid, which is characterized in that the raw material of the oral liquid includes the combination described in any one of claim 1-5 Object.

8. oral liquid according to claim 7, which is characterized in that the raw material includes the soak of raw slurry, raw material One or more of with the extract of raw material.

9. the preparation method of the oral liquid described in a kind of claim 7 or 8, which is characterized in that the preparation method includes will be each The step of raw material is mixed according to formula ratio.

10. preparation method according to claim 9, which is characterized in that include the following steps：

(a) Hei Maka, Herba Cistanches, cynomorium songaricum, American Ginseng, lycium ruthenicum, red matrimony vine, snow chrysanthemum, Cortex Eucommiae, lotus seeds, hawthorn are not crushed, so After impregnate, then squeeze the juice；

(b) ganoderma lucidum is crushed to 100-120 mesh；

(c) it filters, goes out after component, honey and the Cordyceps extract in step (a) and step (b) are mixed by formula ratio Bacterium；

Preferably, the raw material handled in the step (a) further includes one or more of ginseng, Radix Notoginseng and wilsonii；

Preferably, the step (a) further includes following steps：First mashing processing is squeezed the juice again after each component crushes immersion, after squeezing the juice The step of obtained slurries are centrifuged, deaerate, filter, sterilize and are concentrated in vacuo successively obtains the raw slurry of each component.