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CN108079035A - A kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof - Google Patents

A kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof Download PDF

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Publication number
CN108079035A
CN108079035A CN201810131524.2A CN201810131524A CN108079035A CN 108079035 A CN108079035 A CN 108079035A CN 201810131524 A CN201810131524 A CN 201810131524A CN 108079035 A CN108079035 A CN 108079035A
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China
Prior art keywords
nutrient solution
american ginseng
solution
inflammatory
concentration
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Pending
Application number
CN201810131524.2A
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Chinese (zh)
Inventor
陈根龙
刘国华
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Jiangsu Sea Into A Swan Retting Biological Medicine Co Ltd
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Jiangsu Sea Into A Swan Retting Biological Medicine Co Ltd
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Priority to CN201810131524.2A priority Critical patent/CN108079035A/en
Publication of CN108079035A publication Critical patent/CN108079035A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/18Iodine; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/20Elemental chlorine; Inorganic compounds releasing chlorine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/42Phosphorus; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention relates to a kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof, first American Ginseng is placed in 100 DEG C of water impregnate 36 it is small when after remove slag, allotment obtains concentration as 35% American Ginseng extracting solution;Actinomyces, photosynthetic bacteria, lactobacillus, saccharomycete, Bifidobacterium are put into acid conventional medium and cultivated, obtains concentration as 40% acid culture bacterium solution;The acid culture bacterium solution 1% -2% in the step 2, the American Ginseng extracting solution 44% -50% in the step 1 are taken, adds the water mixing of mineral salt 1.01% -2.2% and surplus;Under 20 DEG C of environment, concentration is added in the mixed liquor obtained in the step 3 as 40% lactobacillus mixed liquor 0.1% -0.5%, stand 120 148 it is small when after obtain final hypoglycemic anti-inflammatory nutrient solution.The present invention is capable of providing a kind of mineral trace element proportioning equalize, the physiological activation for promoting function of human body tissue, improves autonomous hypoglycemic anti-inflammatory nutrient solution repaired and can eliminate insulitis of metabolism quality, strengthen immunity and damaged islet cells and preparation method thereof.

Description

A kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof
Technical field
The present invention relates to nutrition liquid preparing process more particularly to a kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof.
Background technology
At present for treating the only hypoglycemic medicine of diabetes, and no elimination insulitis drug, exist single One property, passivity and limitation.Existing hypoglycemic medicine is mainly to block human body to the absorption of glucose to reach the mesh of hypoglycemic , and human body must actually have enough glucose to ensure the storage of inose and liver glycogen, and human body not so will be made long-term The normal function of internal internal organs can be influenced in fatigue dress state.And hypoglycemic medicine be with side effect and significant limitation, Particularly diet can trigger the malnutrition of human body, reduce immunity, be unable to reach the effect of good treatment and rehabilitation, there are no Method eliminates pancreas islet nonspecific inflammation.
The content of the invention
A kind of mineral trace element proportioning equalize the invention aims to overcome the deficiencies in the prior art is provided, is promoted Into the physiological activation of function of human body tissue, the autonomous reparation for being metabolized quality, strengthen immunity and damaged islet cells and energy are improved Eliminate hypoglycemic anti-inflammatory nutrient solution of insulitis and preparation method thereof.
In order to achieve the above objectives, present invention employs following technical solutions.
A kind of hypoglycemic anti-inflammatory nutrient solution, the weight percentages of components specifically included are:Concentration is 35% American Ginseng extracting solution 44% -50%, concentration is that 40% acid bacterium solution 1% -2%, minerals 1.01% -2.2%, the concentration of cultivating is 40% lactobacillus mixed liquor 0.1% -0.5%, surplus is water.
A kind of preparation method of hypoglycemic anti-inflammatory nutrient solution, specifically includes following steps:
Step 1:First by American Ginseng be placed in 100 DEG C of water impregnate 36 it is small when after remove slag, allotment obtain concentration for 35% west American ginseng extracting solution;
Step 2:Actinomyces, photosynthetic bacteria, lactobacillus, saccharomycete, Bifidobacterium are put into acid conventional medium and cultivated, is obtained Concentration is 40% acid culture bacterium solution;
Step 3:Take the acid culture bacterium solution 1%-2% in the step 2, the American Ginseng extracting solution 44% in the step 1- 50%, add the water mixing of mineral salt 1.01% -2.2% and surplus;
Step 4:Under 20 DEG C of environment, concentration is added in the mixed liquor obtained in the step 3 and is mixed for 40% lactobacillus Liquid 0.1% -0.5%, stand 120-148 it is small when after obtain final hypoglycemic anti-inflammatory nutrient solution.
As a further improvement on the present invention, the acid conventional medium is to add in alimentary acetic acid in conventional medium, Its ratio be 6:1.
As a further improvement on the present invention, the mineral salt include trace element magnesium, sodium, phosphorus, sulphur, chlorine, iron, copper, Iodine, cobalt, molybdenum, nickel, fluorine, vanadium, tin, silicon.
Due to the utilization of above-mentioned technical proposal, advantageous effects that technical solution of the present invention is brought:Existing antidiabetic drug If owner blocks human body to the absorption of glucose to achieve the purpose that hypoglycemic, and human body must actually have enough grapes For sugar to ensure the storage of inose and liver glycogen, human body not so will be made, which to be chronically at fatigue dress state, can influence the normal work(of internal internal organs Can, and hypoglycemic medicine is to trigger the malnutrition of human body with side effect and significant limitation, particularly diet, is reduced Immunity is unable to reach the effect of good treatment and rehabilitation, and it is even more impossible to eliminate pancreas islet nonspecific inflammation;By this technology side The nutrient solution that case prepares, which has, is rationally balancedly blended together nutrient for plants with mine trace element, by people Body supplements the compositions such as the mine trace element of the protein of complete equilibrium, amino acid, polysaccharide, vitamin and ionic state comprehensively, Promote the physiological activation of function of human body tissue, improve metabolism quality, the autonomous reparation of strengthen immunity and damaged islet cells disappears Except insulitis.
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail.
First, specific embodiment is prepared:
(1)3 kilograms of American Ginseng is impregnated in 100 degree of 12 kilograms of water 36 it is small when, remove slag to obtain 10 kilograms of extracting solutions(Concentration 35%);
(2)Actinomyces, photosynthetic bacteria, lactobacillus, saccharomycete, Bifidobacterium are put into acid conventional medium and cultivated, it is acid normal It is to add in alimentary acetic acid in conventional medium to advise culture medium, and its ratio be 6:1, take 1 kilogram of bacterium solution(Concentration 40%);
(3)Acid culture bacterium solution is taken to be mixed with American Ginseng extracting solution, is added containing the necessary micro- mineral salt 10 of human body Gram, mineral salt contains trace element:Magnesium, sodium, phosphorus, sulphur, chlorine, iron, copper, iodine, cobalt, molybdenum, nickel, fluorine, vanadium, tin, silicon, add water purification To 99.9 kilograms;
(4)Add in 100 grams of the mixed liquor of lactobacillus(Concentration 40%)The hypoglycemic anti-inflammatory of double centner is obtained when standing 120 is small after mixing Nutrient solution, sterilization packaging.
2nd, the specifically used and example effects of hypoglycemic anti-inflammatory nutrient solution
The instructions of taking of the hypoglycemic anti-inflammatory nutrient solution, it is different for different diabetics its taking dose, take when Between length it is also different.It is specific as follows:
1st, the diabetic that has just detected simultaneously never takes Chinese and Western medicine, and C peptide levels are normal in blood, and instructions of taking is:Often Its taking dose is 150ml to 300ml, in three times, each 50ml to 100ml.The cycle is taken as four months i.e. 120 day.Between not Disconnection, which continues, takes 2 cycles i.e. 240 days, and clinic is controlled Yu and led as more than 90%.
2nd, suffer from diabetes 1-3, take that C peptide levels in 1 to 2 kind of Western medicine and blood are normal, and instructions of taking is:It takes daily Dosage is 120ml, totally four times:In the morning, afternoon and evening it is each before the meal once, added before sleeping once, each 30ml.Uninterruptedly continuously took for 3 week Phase i.e. 360 day or so, clinic control Yu and lead about 75%.
3rd, diabetes 5 years or more are suffered from, two or more Chinese and Western medicine is taken in treatment(Containing insulin injection), and C peptide levels are less than just Ordinary water is put down, and with different degrees of various diabetic keratopathy syndrome phenomenons, taking dose is daily 120ml, in four times, in the morning, afternoon and evening Each before the meal once to be added before sleeping once, each dosage is 30ml.It is uninterrupted to take about 3 cycle i.e. 360 day or so, eliminate sugar It is 95% or so that it is efficient, which to urinate myelodysplastic syndromes,.About 60% or so crowd can realize rehabilitation, and about 85% or so crowd, which can realize to subtract, to stop Medicine.To suffering from diabetes 5 years or more, but do not occur the patient of diabetic keratopathy syndrome, more than 95% diabetic syndrome does not occur.
Case 1:Certain is gone into business, man, 35 years old, hospital just detected diabetes, and I types, C peptide levels are normal, and blood glucose target is 8.5mmol/L(It is normally 6.1mmol/L/following), triglycerides 5.8mmol/L(It is normally below 1.8mmol/L), clothes After this technology nutrient solution 120 days, blood glucose target is below 6.1mmol/L, and triglycerides is 2.0 mmol/L.It takes 240 days Afterwards, blood glucose target is below 6.0mmol/L, and triglycerides 1.56.0mmol/L, binomial is stable normal, no relapse.
Case 2:Chen, man, 55 years old, 5 years diabetes ages or more, II types.C peptide levels are normal, and blood glucose target is 11.76mmol/L(It is normally below 6.1mmol/L), triglycerides 4.8mmol/L(It is normally below 1.8mmol/L), always Bilirubin 25.6mmo l/L(It is normally 5.0-19.0mmol/L), indirect bilirubin 19.2mmol/L(It is normally 0.1- 17.0mmol/L).Clinical treatment takes melbine, daily 6.After taking this technology nutrient solution 90 days, blood glucose target is 5.70mmol/L, triglycerides are 2.18 mmol/L.Total bilirubin is 22.0mmol/L, indirect bilirubin 18.0mmol/L.Stop It takes and continues to take this technology nutrient solution after melbine to 240 days, more than index is normal, and no relapse.
Case 3:Zou, man, 51 years old, 12 years diabetes ages, II types.C peptide levels are less than normal level(It is normal for 0.4 ± 0.2 nmol/L), blood glucose target 11.17mmol/L, clinical treatment takes sulfonylureas and daily 13 of biguanide drug, in additional Medicine decoction, and with diabetes coronary heart disease, failing depending on rate, impotence, weakness of limbs, wound not syndromes such as more.Take this After technical nutrient liquid, vision restoration is normal within 60 days, and 90 days impotence, wounds are not more and the symptom complexs such as weakness of limbs disappear.Continue It takes to after 120 days, disables Chinese medicine, only take melbine 4 daily.Blood glucose is 6.8mmol/L or so.Continue to take this technology Nutrient solution disappears to all Chinese and Western medicines, diabetes coronary heart disease symptom after 240 days, is withdrawn.Blood glucose is 6.0 mmol/L or so.Clothes With this technology nutrient solution to after 360 days, physical rehabilitation, recurrence that so far there are no.
It the above is only the concrete application example of the present invention, protection scope of the present invention be not limited in any way.All uses Equivalent transformation or equivalent replacement and the technical solution formed, all fall within rights protection scope of the present invention.

Claims (5)

1. a kind of hypoglycemic anti-inflammatory nutrient solution, which is characterized in that the weight percentages of components specifically included is:American Ginseng extracting solution 44% -50%, acid culture bacterium solution 1% -2%, minerals 1.01% -2.2%, lactobacillus mixed liquor 0.1% -0.5%, surplus are Water.
2. a kind of hypoglycemic anti-inflammatory nutrient solution according to claim 1, it is characterised in that:The concentration of the American Ginseng extracting solution For 35%, the acid culture bacterial concentration is 40%, and the lactobacillus mixed liquor is 40%.
3. a kind of preparation method of hypoglycemic anti-inflammatory nutrient solution, which is characterized in that specifically include following steps:
Step 1:First by American Ginseng be placed in 100 DEG C of water impregnate 36 it is small when after remove slag, allotment obtain concentration for 35% west American ginseng extracting solution;
Step 2:Actinomyces, photosynthetic bacteria, lactobacillus, saccharomycete, Bifidobacterium are put into acid conventional medium and cultivated, is obtained Concentration is 40% acid culture bacterium solution;
Step 3:Take the acid culture bacterium solution 1%-2% in the step 2, the American Ginseng extracting solution 44% in the step 1- 50%, add the water mixing of mineral salt 1.01% -2.2% and surplus;
Step 4:Under 20 DEG C of environment, concentration is added in the mixed liquor obtained in the step 3 and is mixed for 40% lactobacillus Liquid 0.1% -0.5%, stand 120-148 it is small when after obtain final hypoglycemic anti-inflammatory nutrient solution.
4. a kind of preparation method of hypoglycemic anti-inflammatory nutrient solution according to claim 3, it is characterised in that:It is described acid conventional Culture medium is to add in alimentary acetic acid in conventional medium, and its ratio be 6:1.
5. a kind of preparation method of hypoglycemic anti-inflammatory nutrient solution according to claim 3, it is characterised in that:The mineral salt bag Contain trace element magnesium, sodium, phosphorus, sulphur, chlorine, iron, copper, iodine, cobalt, molybdenum, nickel, fluorine, vanadium, tin, silicon.
CN201810131524.2A 2018-02-09 2018-02-09 A kind of hypoglycemic anti-inflammatory nutrient solution and preparation method thereof Pending CN108079035A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108524592A (en) * 2018-07-11 2018-09-14 昆山绿清婷生物科技有限公司 A kind of prevention diabetic syndrome nutrient solution

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1526419A (en) * 2003-03-06 2004-09-08 陈根龙 Blood sugar and blood fat reducing composite microbial mineral nutrient liquid and its prepn process
US6852707B1 (en) * 1998-12-10 2005-02-08 Suntory Limited Remedies for hyperammonemia
CN106819732A (en) * 2016-12-25 2017-06-13 山东奥博森医药科技有限公司 It is a kind of to prevent and treat fermented beverage of diabetes and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852707B1 (en) * 1998-12-10 2005-02-08 Suntory Limited Remedies for hyperammonemia
CN1526419A (en) * 2003-03-06 2004-09-08 陈根龙 Blood sugar and blood fat reducing composite microbial mineral nutrient liquid and its prepn process
CN106819732A (en) * 2016-12-25 2017-06-13 山东奥博森医药科技有限公司 It is a kind of to prevent and treat fermented beverage of diabetes and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
季宇彬: "《抗癌中药药理与应用》", 28 February 1999, 黑龙江科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108524592A (en) * 2018-07-11 2018-09-14 昆山绿清婷生物科技有限公司 A kind of prevention diabetic syndrome nutrient solution

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Application publication date: 20180529