CN108066167A - A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof - Google Patents
A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof Download PDFInfo
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- CN108066167A CN108066167A CN201810137164.7A CN201810137164A CN108066167A CN 108066167 A CN108066167 A CN 108066167A CN 201810137164 A CN201810137164 A CN 201810137164A CN 108066167 A CN108066167 A CN 108066167A
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- mouthwash
- agent
- acidity
- acid
- antibacterial
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- 239000002324 mouth wash Substances 0.000 title claims abstract description 60
- 229940051866 mouthwash Drugs 0.000 title claims abstract description 49
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 37
- 230000002087 whitening effect Effects 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims description 12
- 238000007794 visualization technique Methods 0.000 title description 2
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 49
- 239000002253 acid Substances 0.000 claims abstract description 24
- 239000002904 solvent Substances 0.000 claims abstract description 23
- 239000004909 Moisturizer Substances 0.000 claims abstract description 22
- 239000000022 bacteriostatic agent Substances 0.000 claims abstract description 22
- 238000005282 brightening Methods 0.000 claims abstract description 22
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 22
- 230000001333 moisturizer Effects 0.000 claims abstract description 22
- 239000003755 preservative agent Substances 0.000 claims abstract description 22
- 230000002335 preservative effect Effects 0.000 claims abstract description 22
- 239000003765 sweetening agent Substances 0.000 claims abstract description 22
- 238000012800 visualization Methods 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims abstract description 11
- 239000008367 deionised water Substances 0.000 claims abstract description 10
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 10
- 239000000243 solution Substances 0.000 claims description 22
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 20
- 239000002826 coolant Substances 0.000 claims description 20
- 238000003756 stirring Methods 0.000 claims description 20
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- 235000012907 honey Nutrition 0.000 claims description 11
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical group CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 10
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 10
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 10
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 229960001859 domiphen bromide Drugs 0.000 claims description 10
- 239000001630 malic acid Substances 0.000 claims description 10
- 235000011090 malic acid Nutrition 0.000 claims description 10
- 229940041616 menthol Drugs 0.000 claims description 10
- 239000004376 Sucralose Substances 0.000 claims description 9
- 244000269722 Thea sinensis Species 0.000 claims description 9
- 235000019408 sucralose Nutrition 0.000 claims description 9
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims description 9
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical group [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 8
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 8
- 235000011187 glycerol Nutrition 0.000 claims description 8
- 239000004302 potassium sorbate Substances 0.000 claims description 8
- 235000010241 potassium sorbate Nutrition 0.000 claims description 8
- 229940069338 potassium sorbate Drugs 0.000 claims description 8
- 108010011485 Aspartame Proteins 0.000 claims description 7
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 7
- 239000000605 aspartame Substances 0.000 claims description 7
- 235000010357 aspartame Nutrition 0.000 claims description 7
- 229960003438 aspartame Drugs 0.000 claims description 7
- 239000003205 fragrance Substances 0.000 claims description 7
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 7
- 244000144730 Amygdalus persica Species 0.000 claims description 6
- 244000024873 Mentha crispa Species 0.000 claims description 6
- 235000014749 Mentha crispa Nutrition 0.000 claims description 6
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 6
- 235000013399 edible fruits Nutrition 0.000 claims description 6
- 235000009569 green tea Nutrition 0.000 claims description 6
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 6
- 239000004299 sodium benzoate Substances 0.000 claims description 6
- 235000010234 sodium benzoate Nutrition 0.000 claims description 6
- -1 sorbierite Substances 0.000 claims description 6
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical group OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 5
- 238000002242 deionisation method Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 229940085605 saccharin sodium Drugs 0.000 claims description 5
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 claims description 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 3
- 238000007792 addition Methods 0.000 claims description 3
- 239000002304 perfume Substances 0.000 claims description 3
- 239000003921 oil Substances 0.000 claims description 2
- OJIYIVCMRYCWSE-UHFFFAOYSA-M Domiphen bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1 OJIYIVCMRYCWSE-UHFFFAOYSA-M 0.000 claims 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims 2
- 229910052708 sodium Inorganic materials 0.000 claims 2
- 239000011734 sodium Substances 0.000 claims 2
- 239000005711 Benzoic acid Substances 0.000 claims 1
- 235000010358 acesulfame potassium Nutrition 0.000 claims 1
- 235000010233 benzoic acid Nutrition 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000003906 humectant Substances 0.000 claims 1
- 235000019204 saccharin Nutrition 0.000 claims 1
- 229940081974 saccharin Drugs 0.000 claims 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical group C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims 1
- 235000013599 spices Nutrition 0.000 claims 1
- 235000019605 sweet taste sensations Nutrition 0.000 claims 1
- 238000004140 cleaning Methods 0.000 abstract description 8
- 206010061218 Inflammation Diseases 0.000 abstract description 4
- 230000023597 hemostasis Effects 0.000 abstract description 3
- 238000010186 staining Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 9
- BHQQXAOBIZQEGI-UHFFFAOYSA-N methyl 2-chlorobutanoate Chemical group CCC(Cl)C(=O)OC BHQQXAOBIZQEGI-UHFFFAOYSA-N 0.000 description 8
- 210000000214 mouth Anatomy 0.000 description 7
- 230000003110 anti-inflammatory effect Effects 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 208000006558 Dental Calculus Diseases 0.000 description 3
- 239000000284 extract Substances 0.000 description 3
- 235000013616 tea Nutrition 0.000 description 3
- 244000118350 Andrographis paniculata Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- UILPJVPSNHJFIK-UHFFFAOYSA-N Paeonol Chemical compound COC1=CC=C(C(C)=O)C(O)=C1 UILPJVPSNHJFIK-UHFFFAOYSA-N 0.000 description 2
- 235000004443 Ricinus communis Nutrition 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000008159 sesame oil Substances 0.000 description 2
- 235000011803 sesame oil Nutrition 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 229940034610 toothpaste Drugs 0.000 description 2
- 239000000606 toothpaste Substances 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 244000004281 Eucalyptus maculata Species 0.000 description 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- QZTLGJIUZACNEG-UHFFFAOYSA-N NCl.N1C=CC=C1 Chemical class NCl.N1C=CC=C1 QZTLGJIUZACNEG-UHFFFAOYSA-N 0.000 description 1
- 241000972672 Phellodendron Species 0.000 description 1
- 241000241413 Propolis Species 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000675 anti-caries Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 150000001669 calcium Chemical class 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- YLTGFGDODHXMFB-UHFFFAOYSA-N isoacetovanillon Natural products COC1=CC=C(C(C)=O)C=C1O YLTGFGDODHXMFB-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002068 microbial inoculum Substances 0.000 description 1
- 229940105902 mint extract Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000037257 muscle growth Effects 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- MLIBGOFSXXWRIY-UHFFFAOYSA-N paeonol Natural products COC1=CC=C(O)C(C(C)=O)=C1 MLIBGOFSXXWRIY-UHFFFAOYSA-N 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 229940069949 propolis Drugs 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229940013618 stevioside Drugs 0.000 description 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 description 1
- 235000019202 steviosides Nutrition 0.000 description 1
- 229910001631 strontium chloride Inorganic materials 0.000 description 1
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/22—Peroxides; Oxygen; Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of antibacterial whitening acidity mouthwash of visualization, by forming following weight percentage components：Sweetener 0.003% ~ 0.1%；Acid 0.1%~0.5%；Moisturizer 2%~15%；Essence 0.05%~0.5%；Brightening agent 0.1%~5%；Solubilizer 0.5%~2.5%；Bacteriostatic agent 0.02%~0.05%；Preservative 0.1%~0.4%；Deionized water surplus；The present invention also provides the methods for preparing the antibacterial whitening acidity mouthwash of visualization.The present invention to oral cleaning, dispel implication and antibacterial, hemostasis and anti-inflammation function while, can effectively, the removing of adhesion and staining quick, that thoroughly realize tooth, make tooth nature brilliant white.
Description
Technical field
The present invention relates to oral care product technical field more particularly to a kind of antibacterial whitening acidity mouthwash of visualization and
Its preparation method.
Background technology
With the improvement of living standards, people increasingly improve the attention rate of oral health, common oral care is also no longer
It is confined to brush teeth twice sooner or later, the species and form demand to oral care product tend to diversification and fashion-orientation.Mouthwash is
Through into the necessity in for people's lives, it is easy to use, and effect can be equal to toothpaste, and use is more convenient than toothpaste, but mesh
The mouthwash of preceding market often act on it is single, and for a long time use protective effect is not had to tooth.It is also, existing at present
The acid-base value of mouthwash be generally neutrality, main function include antibacterial bacteriostatic, improve oral peculiar smell, anti-inflammatory, cleaning oral cavity it is thin
Bacterium and tartar etc., species include Chinese medicine draft class, natural plant extracts class and drug ingedient composite class.
CN103385821A discloses a kind of mouthwash of deep layer removal tartar, and constituent has：Glycerine, polyoxy third
Alkene, western pyrrole chloramines, peppermint, motherwort extracting solution, tea polyphenols, strontium chloride, deionized water.
105687083 A of CN disclose a kind of antibacterial hemostasis mouthwash and preparation method thereof, and the mouthwash is by following weight
Raw material be made：0.5~1 part of activated calcium powder, 0.1~2 part of Honegsukle flower P.E, 0.1~1.5 part of propolis, Paeonol 0.2~
0.5 part, 0.1~2 part of deep sea salt, 0.1~0.5 part of mint extract, 0.5~3 part of stevioside, 0.5~1 part of loguat leaf, eucalyptus
0.1~0.3 part of oil, 2~3 parts of old tea liquid, 90~95 parts of pure water.
A kind of long-acting bacteriostatic type mouthwashes of 106038389 A of CN, using deionized water as main component, and at least add
Added with the combination of phellodendron extract, capillary extract, Andrographis Paniculata and Herba Verbenae.This case is extracted using Cortex Phellodendri
The mode that object, capillary extract, Andrographis Paniculata and Herba Verbenae are used in combination, can play quickly prevents gum from going out
The effect of blood, long-acting inhibition oral bacteria, achieve the purpose that treat both principal and secondary aspect of disease.
Various mouthwashes described in above-mentioned patent, although play the antibacterial anti-inflammatory to tooth and oral cavity, cleaning oral cavity and
Tooth and the effect for being effectively improved oral peculiar smell, but it is neutrality, the effect of cleaning tartar and oral foreign body is not
Substantially, how effectively, quickly, thoroughly realize the removing of the adhesion and staining of tooth, keep tooth brilliant white, simultaneously
It plays to tooth and oral antimicrobial anti-inflammatory effects, is to restrict the problem that current mouth cavity daily nurses industry, and pure Chinese medicine
The mouthwash of ingredient primarily serves the effect of reparation, anti-inflammatory, and the Chinese medicine effect for acting on outside is often slow, for tooth
Lightening effect is not obvious.
The content of the invention
In view of the deficienciess of the prior art, the technical problem to be solved by the invention is to provide it is a kind of to oral cleaning,
While dispelling implication and antibacterial, hemostasis and anti-inflammation function, make tooth nature brilliant white the antibacterial whitening acidity mouthwash of visualization and
Its preparation method.
In order to solve the above technical problems, the technical solution used in the present invention is：A kind of antibacterial whitening acidity of visualization is gargled
Saliva, by forming following weight percentage components：
Sweetener 0.003% ~ 0.1%；
Acid 0.1%~0.5%；
Moisturizer 2%~15%；
Essence 0.05%~0.5%；
Brightening agent 0.1%~5%；
Solubilizer 0.5%~2.5%；
Bacteriostatic agent 0.02%~0.05%；
Preservative 0.1%~0.4%；
Deionized water surplus；
The PH of the mouthrinse product is 3~5.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, by forming following weight percentage components：
Sweetener 0.05%；
Acid 0.25%；
Moisturizer 8%；
Essence 0.3%；
Brightening agent 2.5%；
Solubilizer 1.5%；
Bacteriostatic agent 0.03%；
Preservative 0.2%；
Deionized water surplus；
The PH of the mouthrinse product is 4.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, the sweetener for saccharin sodium, D-sorbite, Sucralose,
One or more in Aspartame, honey element, acid are malic acid, and moisturizer is one in glycerine, sorbierite, propylene glycol
Kind is several, and essence is the fruit such as green tea, spearmint, honey peach perfume or the fragrance of a flower, and solubilizer hydrogenates castor for polysorbas20 or PEG-40
Sesame oil, brightening agent are hydrogen peroxide, and preservative is potassium sorbate, one or more of sodium benzoate, methyl hydroxybenzoate, the suppression
Microbial inoculum is Domiphen bromide.
The antibacterial whitening acidity mouthwash of above-mentioned visualization, the mouthwash also added with weight percent be 0.5% it is cool
Taste agent, the coolant agent are menthol.
It is a kind of to prepare the method for visualizing antibacterial whitening acidity mouthwash, include the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3~5 mouthwash finished product.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the step（2）Middle addition weight percent
For 0.5% coolant agent.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the sweetener is saccharin sodium, D-sorbite,
One or more in Sucralose, Aspartame, honey element, acid are malic acid, and moisturizer is glycerine, sorbierite, third
One or more of glycol, essence for the fruit such as green tea, spearmint, honey peach are fragrant or the fragrance of a flower, solubilizer for polysorbas20 or
Cremophor RH40, brightening agent are hydrogen peroxide, and preservative is potassium sorbate, one kind in sodium benzoate, methyl hydroxybenzoate
Or it is several, the bacteriostatic agent is Domiphen bromide.
The preparation method of the above-mentioned antibacterial whitening acidity mouthwash of visualization, the coolant agent are menthol.
The present invention, which visualizes the advantages of antibacterial whitening acidity mouthwash and preparation method thereof, is：It adds acid ingredient and brightens
Agent so that the mouthwash in acidity, to oral cleaning, dispel implication and antibacterial hemostatic function while, can effectively, quickly,
It thoroughly realizes the removing of the adhesion and staining of tooth, keeps tooth brilliant white.Mouthwash of the present invention is applied widely,
It is easy to use, there is cleaning, antibacterial, anti-caries and fresh breath, it is without any side effects；This mouthwash formula is only
It is special, fastidious, manufacturing method is simple, by multiple clinical research, to because of pathogenic bacteria such as Candida albicans, staphylococcus aureuses
Caused oral inflammation has unique antibacterial anti-inflammatory, analgesic promoting muscle growth functions, can effectively inhibit the formation of oral inflammation, maintain mouth
Chamber bacterium state balances, and moment cleaning oral cavity, control effect is good, is the external application type oral cavity medicine that a kind of preferable prevention is integrated with treatment
Object.
Specific embodiment
The present invention is described in further details with reference to specific embodiment；
Embodiment 1：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.003%；0.1 % of acid；Moisturizer 2%；Essence 0.05%；Brightening agent 0.1%；Solubilizer 0.5%；Bacteriostatic agent 0.02%；It is anti-
Rotten agent 0.1%；Deionized water surplus；The PH of the mouthrinse product is 5.Wherein, sweetener is saccharin sodium, D-sorbite, trichlorine
Sucrose, acid are malic acid, and moisturizer is glycerine, sorbierite, and essence is the green tea fragrance of a flower, and solubilizer is polysorbas20, brightening agent
For hydrogen peroxide, preservative is potassium sorbate, sodium benzoate, and bacteriostatic agent uses Domiphen bromide.The mouthwash is also added with weight
Percentage is 0.5% coolant agent.In the present embodiment, coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 5 mouthwash finished product.
Wherein, sweetener is saccharin sodium, D-sorbite, Sucralose, and acid is malic acid, and moisturizer is glycerine, mountain
Pears alcohol, essence are the green tea fragrance of a flower, and solubilizer is polysorbas20, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, benzoic acid
Sodium, bacteriostatic agent use Domiphen bromide.The mouthwash is also added with the coolant agent that weight percent is 0.5%.It is cool in the present embodiment
Taste agent is menthol.
Embodiment 2：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.05%；Acid 0.25%；Moisturizer 8%；Essence 0.3%；Brightening agent 2.5%；Solubilizer 1.5%；Bacteriostatic agent 0.03%；Preservative
0.2%；Deionized water surplus；The PH of the mouthrinse product is 4.Wherein, sweetener is D-sorbite, Sucralose, A Siba
Sweet tea, acid are malic acid, and moisturizer is sorbierite, propylene glycol, and essence is the spearmint fragrance of a flower, and solubilizer hydrogenates castor for PEG-40
Sesame oil, brightening agent are hydrogen peroxide, and preservative is sodium benzoate, methyl hydroxybenzoate, and bacteriostatic agent uses Domiphen bromide.Mouthwash also adds
There is the coolant agent that weight percent is 0.5%, in the present embodiment, coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 4 mouthwash finished product.
Wherein, sweetener is D-sorbite, Sucralose, Aspartame, and acid is malic acid, and moisturizer is sorb
Alcohol, propylene glycol, essence are the spearmint fragrance of a flower, and solubilizer is Cremophor RH40, and brightening agent is hydrogen peroxide, and preservative is
Sodium benzoate, methyl hydroxybenzoate, bacteriostatic agent use Domiphen bromide.Mouthwash is also added with the coolant agent that weight percent is 0.5%, this
In embodiment, coolant agent is menthol.
Embodiment 3：
A kind of antibacterial whitening acidity mouthwash of visualization of the present embodiment, by forming following weight percentage components：Sweetener
0.1%；Acid 0.5%；Moisturizer 15%；Essence 0.5%；Brightening agent 5%；Solubilizer 2.5%；Bacteriostatic agent 0.05%；Preservative
0.4%；Deionized water surplus；The PH of the mouthrinse product is 3.Wherein, sweetener is Sucralose, Aspartame, sweetness
Element, acid are malic acid, and moisturizer is glycerine, propylene glycol, and essence is fragrant for honey peach fruit, and solubilizer is polysorbas20, is brightened
Agent is hydrogen peroxide, and preservative is potassium sorbate, methyl hydroxybenzoate, and bacteriostatic agent uses Domiphen bromide.Mouthrinse components in the present embodiment
Also added with the coolant agent that weight percent is 0.5%, the coolant agent is menthol.
The present embodiment prepares the method for visualizing antibacterial whitening acidity mouthwash, includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence, 0.5% coolant agent stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3 mouthwash finished product.
Wherein, sweetener is Sucralose, Aspartame, honey element, and acid is malic acid, and moisturizer is glycerine, third
Glycol, essence is fragrant for honey peach fruit, and solubilizer is polysorbas20, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, oxybenzene
Methyl esters, bacteriostatic agent use Domiphen bromide.Mouthrinse components are also added with the coolant agent that weight percent is 0.5%, institute in the present embodiment
Coolant agent is stated as menthol.
Certainly, it is limitation of the present invention that above description, which is not, and the present invention is also not limited to the example above, the art
Those of ordinary skill, in the essential scope of the present invention, the variations, modifications, additions or substitutions made should all belong to the present invention
Protection domain.
Claims (8)
1. a kind of antibacterial whitening acidity mouthwash of visualization, which is characterized in that by forming following weight percentage components：
Sweetener 0.003% ~ 0.1%；
Acid 0.1%~0.5%；
Moisturizer 2%~15%；
Essence 0.05%~0.5%；
Brightening agent 0.1%~5%；
Solubilizer 0.5%~2.5%；
Bacteriostatic agent 0.02%~0.05%；
Preservative 0.1%~0.4%；
Deionized water surplus；
The PH of the mouthrinse product is 3~5.
2. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that, by following weight percent
Component forms：
Sweetener 0.05%；
Acid 0.25%；
Moisturizer 8%；
Essence 0.3%；
Brightening agent 2.5%；
Solubilizer 1.5%；
Bacteriostatic agent 0.03%；
Preservative 0.2%；
Deionized water surplus；
The PH of the mouthrinse product is 4.
3. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that：The sweetener is saccharin
One or more in sodium, D-sorbite, Sucralose, Aspartame, honey element, acid are malic acid, and moisturizer is sweet
One or more of oil, sorbierite, propylene glycol, essence is the fruit such as green tea, spearmint, honey peach is fragrant or the fragrance of a flower, solubilizer
For polysorbas20 or Cremophor RH40, brightening agent is hydrogen peroxide, and preservative is potassium sorbate, sodium benzoate, oxybenzene first
One or more of ester, the bacteriostatic agent are Domiphen bromide.
4. the antibacterial whitening acidity mouthwash of visualization according to claim 1, it is characterized in that：The mouthwash is also added with
Weight percent is 0.5% coolant agent, and the coolant agent is menthol.
5. a kind of prepare the method for visualizing antibacterial whitening acidity mouthwash, which is characterized in that includes the following steps：
（1）, sweetener and acid are added in stirring and dissolving in water deionization, then moisturizer is added in aqueous solution, stirring is equal
It is even and form finely dispersed water-soluble clarified solution；
（2）, solubilizer, essence stirred to form uniform oily solution；
（3）, in the state of stirring, oily solution is slowly added into water-soluble clarified solution, be uniformly mixed；
（4）, by brightening agent, bacteriostatic agent, preservative add in step（3）In the aqueous solution of acquisition, it is mixed evenly；
（5）, stop stirring, stand 24 it is small when, filtering, after aseptic process PH be 3~5 mouthwash finished product.
6. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 5, it is characterized in that：The step
（2）The coolant agent that middle addition weight percent is 0.5%.
7. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 5, it is characterized in that：The sweet taste
Agent is saccharin sodium, the one or more in D-sorbite, Sucralose, Aspartame, honey element, and acid is malic acid, is protected
Humectant is one or more of glycerine, sorbierite, propylene glycol, and essence is the fruit such as green tea, spearmint, honey peach perfume or flower
Perfume (or spice), solubilizer are polysorbas20 or Cremophor RH40, and brightening agent is hydrogen peroxide, and preservative is potassium sorbate, benzoic acid
One or more of sodium, methyl hydroxybenzoate, the bacteriostatic agent are Domiphen bromide.
8. the preparation method of the antibacterial whitening acidity mouthwash of visualization according to claim 6, it is characterized in that：The cool taste
Agent is menthol.
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