CN107927198A - One kind drinks milk powder and preparation method thereof for premature - Google Patents
One kind drinks milk powder and preparation method thereof for premature Download PDFInfo
- Publication number
- CN107927198A CN107927198A CN201711373470.2A CN201711373470A CN107927198A CN 107927198 A CN107927198 A CN 107927198A CN 201711373470 A CN201711373470 A CN 201711373470A CN 107927198 A CN107927198 A CN 107927198A
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- feed liquid
- milk powder
- premature
- vitamin
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- 239000000843 powder Substances 0.000 title claims abstract description 82
- 235000013336 milk Nutrition 0.000 title claims abstract description 56
- 239000008267 milk Substances 0.000 title claims abstract description 56
- 210000004080 milk Anatomy 0.000 title claims abstract description 56
- 230000002028 premature Effects 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title abstract description 6
- 239000007788 liquid Substances 0.000 claims abstract description 68
- 239000000203 mixture Substances 0.000 claims abstract description 51
- 102000007544 Whey Proteins Human genes 0.000 claims abstract description 30
- 108010046377 Whey Proteins Proteins 0.000 claims abstract description 30
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 30
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- 239000011782 vitamin Substances 0.000 claims abstract description 29
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- 239000002131 composite material Substances 0.000 claims abstract description 17
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- 235000021119 whey protein Nutrition 0.000 claims abstract description 16
- 239000005862 Whey Substances 0.000 claims abstract description 14
- 150000001875 compounds Chemical class 0.000 claims abstract description 14
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- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 claims abstract description 10
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- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
- 241000218636 Thuja Species 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 208000006399 Premature Obstetric Labor Diseases 0.000 description 3
- 206010036600 Premature labour Diseases 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 210000002249 digestive system Anatomy 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000003595 mist Substances 0.000 description 3
- 208000026440 premature labor Diseases 0.000 description 3
- 229940091258 selenium supplement Drugs 0.000 description 3
- 244000298479 Cichorium intybus Species 0.000 description 2
- 235000007542 Cichorium intybus Nutrition 0.000 description 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 2
- 208000034423 Delivery Diseases 0.000 description 2
- 235000019482 Palm oil Nutrition 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000020247 cow milk Nutrition 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- BVTBRVFYZUCAKH-UHFFFAOYSA-L disodium selenite Chemical compound [Na+].[Na+].[O-][Se]([O-])=O BVTBRVFYZUCAKH-UHFFFAOYSA-L 0.000 description 2
- 239000000174 gluconic acid Substances 0.000 description 2
- 235000012208 gluconic acid Nutrition 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 208000018773 low birth weight Diseases 0.000 description 2
- 231100000533 low birth weight Toxicity 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 230000000050 nutritive effect Effects 0.000 description 2
- 239000002540 palm oil Substances 0.000 description 2
- 239000001103 potassium chloride Substances 0.000 description 2
- 235000011164 potassium chloride Nutrition 0.000 description 2
- 235000007715 potassium iodide Nutrition 0.000 description 2
- 239000011781 sodium selenite Substances 0.000 description 2
- 229960001471 sodium selenite Drugs 0.000 description 2
- 235000015921 sodium selenite Nutrition 0.000 description 2
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- NOQGZXFMHARMLW-UHFFFAOYSA-N Daminozide Chemical compound CN(C)NC(=O)CCC(O)=O NOQGZXFMHARMLW-UHFFFAOYSA-N 0.000 description 1
- 102000008857 Ferritin Human genes 0.000 description 1
- 108050000784 Ferritin Proteins 0.000 description 1
- 238000008416 Ferritin Methods 0.000 description 1
- 235000002918 Fraxinus excelsior Nutrition 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 206010041092 Small for dates baby Diseases 0.000 description 1
- 239000002956 ash Substances 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004641 brain development Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 229940108928 copper Drugs 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 238000010612 desalination reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- VZFRNCSOCOPNDB-UHFFFAOYSA-N domoic acid Natural products OC(=O)C(C)C=CC=C(C)C1CNC(C(O)=O)C1CC(O)=O VZFRNCSOCOPNDB-UHFFFAOYSA-N 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 235000021323 fish oil Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 229960003284 iron Drugs 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 230000004768 organ dysfunction Effects 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- MBWXNTAXLNYFJB-LKUDQCMESA-N phylloquinone Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CCCC(C)CCCC(C)CCCC(C)C)=C(C)C(=O)C2=C1 MBWXNTAXLNYFJB-LKUDQCMESA-N 0.000 description 1
- -1 phytondione Chemical compound 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C21/00—Whey; Whey preparations
- A23C21/06—Mixtures of whey with milk products or milk components
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C21/00—Whey; Whey preparations
- A23C21/04—Whey; Whey preparations containing non-milk components as source of fats or proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of milk powder drunk for premature and preparation method thereof, which includes following components：35%~50% desalted whey powder, 20%~26% compound lard, 5%~20% lactose, 8%~12% concentrated whey protein powder, 3%~10% medium chain triglyceride, 1%~3% prebiotic compositions, 0.7%~0.9% composite mineral matter, 0.3%~0.4% multi-vitamins, 0.3%~0.6% docosahexaenoic acid grease, 0.3%~0.6% arachidonic acid oil, 0.03%~0.1% lactoferrin, 0.02%~0.05% nucleotide, above-mentioned percentage account for the quality of milk powder percentage for each component.Preparation method obtains feed liquid A to be uniformly mixed desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions and water to being completely dissolved；By compound lard and medium chain triglyceride, it is uniformly mixed, obtains feed liquid B；Feed liquid B and A are mixed, homogeneous, obtains feed liquid C；Multi-vitamins and composite mineral matter are added in feed liquid C, are sterilized, are concentrated, it is dry, obtain semi-finished product E and docosahexaenoic acid grease, arachidonic acid oil, lactoferrin and nucleotide are dry-mixed, up to milk powder.
Description
Technical field
The invention belongs to dairy products field, and in particular to one kind drinks milk powder and preparation method thereof for premature.
Background technology
Gestational age is known as premature or premature infant in the 37 foot Zhou Yiqian life birth babies being born, its birth weight major part exists
Below 2500g, head circumference are difference person compared with term infant in below 33cm, its organ dysfunction and adaptability, and it is special should to give premature
Nursing.It is all because of factors such as placenta insufficiencies and birth weight is relieved to below the 10th hundredths of gestational age normal type or relatively flat
Person is known as small for gestational age infant (small-for-date infant, dysmaturity) below low two standard deviations of mean.Medically also birth weight
Below 2500g's is referred to as the infant of low-birth weight, and birth weight is called very low birth weight infant less than 1500g person, wherein all including premature labor
Youngster and less than gestational age person.
In 20,000,000 neonates being born every year in China, premature nearly reaches 2,000,000, and ratio reaches 10%.Premature labor
Youngster is a kind of special crowd, lacks the enteron aisle digestive system of maturation, constitution is compared with normal birth since body development is incomplete
Baby is weak, therefore premature has bigger difference to the demand of nutrient and the baby of normal birth.
The gastrointestinal function of premature be it is ripe without being broken into the development at fetus age, the nursing of premature be typically by
Dilution milk starts, and gradually increases concentration, milk amount is also stepped up, incremental, to adapt to the intestines and stomach of its undeveloped mature.It is right
The nutritional need of premature will not only consider that nutrient lacks the problem of causing, it is also contemplated that these nutrients are excessively brought
Possibility risk.
Therefore due to the complexity of premature's nutrient demand, preterm formula milk powder to formula design, raw material specification and
Process of manufacture etc. is required for formulating stringent standard, so as to limit the such product of many enterprise developments.At present, exist
The preterm formula milk powder sold in China market does not have domestic brand also, and is from American-European enterprise.
The content of the invention
The object of the present invention is to provide a kind of preterm formula milk powder, there is provided a kind of manufacture method, it is more particularly to a kind of early
Newborn baby's formula milk and its manufacture method.
The technical problems to be solved by the invention are that the enteron aisle digestive system for being directed to premature crowd is immature, digest and inhale
The features such as utilization rate is low is received, optimization is adjusted to the protein composition, fat composition and carbohydrate composition of formula, is added
Alpha lactalbumin easy to digest and absorb (being brought into by concentrated whey protein powder), medium chain triglyceride, and make the energy in formula
The index such as amount, protein and some mineral matters, vitamin is higher than GB 25596-2010《National food safety standard special medicine
Purposes infant formula general rule》Requirement, to meet the needs of premature is to nutrition.The preterm formula milk powder of the present invention
Each nutrient compositions content is designed according to the physilogical characteristics and nutritional need of premature, single source of nutrition can be used as to meet early
The nutritional need of newborn baby crowd.
The present invention solves above-mentioned technical problem by the following technical programs.
One kind drinks milk powder for premature, it is characterised in that the milk powder includes following components：35%~50% desalination breast
Chain is sweet in clear powder, 20%~26% compound lard, 5%~20% lactose, 8%~12% concentrated whey protein powder, 3%~10%
Oily three esters, 1%~3% prebiotic compositions, 0.7%~0.9% composite mineral matter, 0.3%~0.4% multi-vitamins,
0.3%~0.6% docosahexaenoic acid grease, 0.3%~0.6% arachidonic acid oil, 0.03%~0.1% newborn iron egg
In vain, 0.02%~0.05% nucleotide, above-mentioned percentage account for the quality of milk powder percentage for each component.
Further optimize, the species of vitamin and content are in milk powder described in per 100g：The content of vitamin A for 520~
920μg RE；The content of vitamin D is 6.8~13.1 μ g；The content of vitamin E is 8.2~15.6mg α-TE；Vitamin K1's
Content is 60~125 μ g；Vitamin B1Content be 450~1280 μ g；Vitamin B2Content be 850~2100 μ g；Vitamin
B6Content be 510~900 μ g；Vitamin B12Content be 2.3~8.2 μ g；The content of niacinamide is 3000~6700 μ g；Leaf
The content of acid is 85~235 μ g；The content of pantothenic acid is 3600~7900 μ g；Ascorbic content is 100~280mg；Biotin
Content be 18~55 μ g；The species and content of mineral matter element be：The content of sodium is 125~300mg；The content of potassium is 400
~950mg；The content of copper is 215~635 μ g；The content of magnesium is 32~75mg；The content of iron is 4.9~8.6mg；The content of zinc
For 2.9~6.4mg；The content of manganese is 70~380 μ g；The content of calcium is 370~780mg；The content of phosphorus is 200~500mg；Iodine
Content be 76~275 μ g；The content of chlorine is 280~610mg；The content of selenium is 17~42 μ g.
Further optimization, alpha lactalbumin content >=30% wherein in concentrated whey protein powder.
Further optimization, wherein prebiotic compositions for 40%~60% polyfructosan, 20%~30% oligofructose and
The mixture of 20%~30% galactooligosaccharide, above-mentioned percentage account for the mass percent of the prebiotic compositions for each component.
Further optimization, wherein compound lard by 1,3-Dioleic acid 2-palmitoyl triglyceride, sunflower oil, rapeseed oil and
Coconut oil forms, and mass ratio is 8~10:4~6:4~6:1~2.
Further optimization, the composition of the multi-vitamins include axerophtholum aceticum, Vitamin D3, d l- α-acetic acid life
Educate phenol, phytondione, thiamine hydrochloride, riboflavin, puridoxine hydrochloride, cyanocobalamin, niacinamide, D-VB5 calcium, L- Vitamin Cs
Acid and D-Biotin；The composition of composite mineral matter includes calcium carbonate, potassium chloride, sodium chloride, calcium phosphate, magnesium sulfate, gluconic acid
Copper, ferrous gluconate, zinc sulfate, manganese sulfate, potassium iodide and sodium selenite.
It is a kind of to prepare the method that milk powder is drunk for premature, comprise the following steps：
(1) by 35%~50% desalted whey powder, 5%~20% lactose, 8%~12% concentrated whey protein powder, 1%~
3% prebiotic compositions and water are uniformly mixed to being completely dissolved, and obtain feed liquid A；
(2) by 20%~26% compound lard and 3%~10% medium chain triglyceride, it is uniformly mixed, obtains feed liquid B；
(3) the feed liquid B and the feed liquid A are uniformly mixed, incorporation time is 10~20 minutes, and homogeneous after mixing, obtains
Feed liquid C；
(4) 0.3%~0.4% multi-vitamins and 0.7%~0.9% composite mineral matter are separately added into water completely molten
Xie Hou, is added in feed liquid C, is uniformly mixed, obtains feed liquid D, add water adjust the solid concentration mass percent of feed liquid D to
15.0%~17.0%；
(5) the feed liquid D is sterilized, concentrated, it is dry, obtain semi-finished product E；By semi-finished product E and 0.3%~0.6% 2
Dodecahexaene acid lipid, 0.3%~0.6% arachidonic acid oil, 0.03%~0.1% lactoferrin and 0.02%~
0.05% nucleotide is dry-mixed, and above-mentioned percentage accounts for the quality of milk powder percentage for each component, up to the product.
Further optimization, the temperature of the middle mixing of step (2) is 50~55 DEG C, and the time of mixing is 10~20 minutes.
Further optimization, the homogeneous described in step (3) be double-stage homogenization, wherein the pressure of level-one homogeneous be 18~
20MPa, the pressure of double-stage homogenization is 3~5MPa, and homogenizing temperature is 55~60 DEG C.
Further optimize, dry-mixed temperature is 20~30 DEG C in step (5), relative humidity≤60%.
In the present invention, the preemie that the preterm formula milk powder is preferably suitable for 0~6 years old eats.
On the basis of common knowledge of the art, above-mentioned each optimum condition, can be combined, each preferably real up to the present invention
Example.
In the present invention, the raw material is food-grade, commercially available.
Compared with prior art, the beneficial effects of the present invention are：
The present invention for premature crowd enteron aisle digestive system it is immature, digest and absorb the features such as rate is low, to
Protein composition, fat composition and the carbohydrate composition of side optimize adjustment, and it is required to enhance intelligent development of premature infants
Various trace elements.Each nutrient compositions content of the preterm formula milk powder of the present invention is according to the physilogical characteristics of premature
And nutritional need design, lactalbumin accounts for the ratio of gross protein and reaches 100% in formula, and wherein α-lactalbumin content reaches
More than 35%, the ratio that medium chain triglyceride accounts for total fat reaches 10%~35%, therefore inventive formulation is easier by premature labor
Youngster absorbs and improves metabolic efficiency.Formula also added specific composition combination of prebiotics (polyfructosan, oligofructose and
Galactooligosaccharide), promote intestines peristalsis.Docosahexaenoic acid and arachidonic acid contribute to the brain development of premature.Breast
Ferritin and nucleotide help to strengthen the immunity of premature.It can meet the nutrition of premature crowd as single source of nutrition
Demand.
Brief description of the drawings
Fig. 1 is the flow diagram of the preparation method of the present invention that milk powder is drunk for premature.
Embodiment
Embodiment of the present invention is described in detail with reference to embodiment and Figure of description,
It will be appreciated by those skilled in the art that the following example is merely to illustrate the present invention, and it is not construed as the limitation present invention's
Scope.
Below by technical solution, the content of the invention is described further.
The manufacture method of preterm formula milk powder of the present invention, it comprises the following steps：
(1) dispensing：Matched by said components, by desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions
It is uniformly mixed with water to being completely dissolved, obtains feed liquid A, feeds order in no particular order when material mixes；
(2) carburetion：Compound lard and medium chain triglyceride are uniformly mixed, obtain feed liquid B；
(3) mix：The feed liquid B and the feed liquid A are uniformly mixed, feed liquid C is obtained after homogeneous；
(4) vitamin dissolves：After multi-vitamins are completely dissolved in water, it is added in feed liquid C, is uniformly mixed, obtains
Feed liquid D；
(5) mineral matter dissolves：After composite mineral matter is completely dissolved in water, it is added in feed liquid D, is uniformly mixed, obtains
Feed liquid E；
(6) powder processed：The feed liquid E is sterilized, is concentrated, it is dry, obtain semi-finished product F；
(7) it is dry-mixed：By the semi-finished product F and docosahexaenoic acid grease, arachidonic acid oil, lactoferrin, core
Thuja acid is dry-mixed, to obtain the final product.
Wherein, the content of ashes of the desalted whey powder is less than 3.5%.
Wherein, the compound lard is (8.0~10.0) by mass ratio:(4.0~6.0):(4.0~6.0):(1.0~
2.0) bis- oleic acid 2- palmitic acids of 1,3-, three ester, sunflower oil, rapeseed oil and coconut oil composition.
Wherein, the alpha lactalbumin content of the concentrated whey protein powder is not less than 30%.
Wherein, the prebiotic compositions are mass percentages for 40~60% polyfructosans, 20~30% oligomeric
The mixture of fructose, 20~30% galactooligosaccharides.
Wherein, the composition of the multi-vitamins include axerophtholum aceticum, Vitamin D3, d l- α-D-α-tocopherol acetate,
Phytondione, thiamine hydrochloride, riboflavin, puridoxine hydrochloride, cyanocobalamin, niacinamide, D-VB5 calcium, L-AA and D-
Biotin.
The composition and dosage of the multi-vitamins can the preterm formula milk powder finished product according to the present invention dimension
Raw cellulose content is adjusted, and the content of various vitamins in preterm formula milk powder of the present invention is reached this area spy
The content's index of each vitamin in different medical usage infant formula.It is preferred that the preterm formula described in per 100g
The species and content of vitamin described in milk powder be：The content of vitamin A is the μ g RE of 520 μ g RE~920；Vitamin D contains
Measure as the μ g of 6.8 μ g~13.1；The content of vitamin E is 8.2mg α-TE~15.6mg α-TE；Vitamin K1Content for 60 μ g~
125μg；Vitamin B1Content be the μ g of 450 μ g~1280；Vitamin B2Content be the μ g of 850 μ g~2100；Vitamin B6Contain
Measure as the μ g of 510 μ g~900；Vitamin B12Content be the μ g of 2.3 μ g~8.3；The content of niacinamide is the μ g of 3000 μ g~6700；Leaf
The content of acid is the μ g of 85 μ g~235；The content of pantothenic acid is the μ g of 3600 μ g~7900；Ascorbic content is 100mg~280mg；
The content of biotin is the μ g of 18 μ g~55.
Wherein, the composite mineral matter can be it is commonly used in the art be capable of providing calcium, chlorine, sodium, magnesium, phosphorus, copper,
The mineral matter elements such as iron, zinc, manganese, calcium, iodine and selenium, it can be that uniformly mixed semi-finished product compounding is former for several mineral materials monomer
Material.The composite mineral matter is calcium carbonate, potassium chloride, sodium chloride, calcium phosphate, magnesium sulfate, copper gluconate, gluconic acid are sub-
Iron, zinc sulfate, manganese sulfate, potassium iodide and sodium selenite.
The composition and dosage of the composite mineral matter can the preterm formula milk powder finished product according to the present invention ore deposit
Content of material is adjusted, and the content of various mineral matters in preterm formula milk powder of the present invention is reached this area spy
The content's index of each mineral matter in different medical usage infant formula.It is preferred that the preterm formula described in per 100g
The species and content of mineral matter described in milk powder be：The content of sodium is 125mg~300mg；The content of potassium is 400mg~950mg；
The content of copper is the μ g of 215 μ g~635；The content of magnesium is 32mg~75mg；The content of iron is 4.9mg~8.6mg；The content of zinc is
2.9mg~6.4mg；The content of manganese is the μ g of 70 μ g~380；The content of calcium is 370mg~780mg；The content of phosphorus for 200mg~
500mg；The content of iodine is the μ g of 76 μ g~275；The content of chlorine is 280mg~610mg；The content of selenium is the μ g of 17 μ g~42.
Further, in step (1), by desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions etc.
Raw material is added in 40 DEG C~45 DEG C water after dissolving, is mixed 15~20 minutes.
Further, in step (2), compound lard and medium chain triglyceride is first preheated to 50~55 DEG C, remixed
10~20 minutes.
Further, in step (3), feed liquid B and feed liquid A is mixed 10~20 minutes.
Further, in step (3), the homogeneous is double-stage homogenization, and the pressure of wherein level-one homogeneous is preferably
18MPa~20MPa, the pressure of double-stage homogenization are preferably 3MPa~5MPa, and the temperature of homogeneous is preferably 55 DEG C~60 DEG C.
Further, in step (4), after multi-vitamins are completely dissolved in 40~45 DEG C of water, it is added to feed liquid C
In, mix 10~15 minutes, obtain feed liquid D.
Further, in step (5), after composite mineral matter is completely dissolved in 40~45 DEG C of water, it is added to feed liquid D
In, mix 10~15 minutes, obtain feed liquid E, the solid concentration of feed liquid E is 15.0~17.0wt%.
Further, in step (6), the sterilization is pasteurize, and the temperature of sterilization is 88~92 DEG C, sterilization
Time is 25~30 seconds；The concentration is triple effect vacuum concentration process, and the feed liquid solid concentration after the concentration is 48
~50wt%；The drying is spray drying, and preferably pressure spray dryer, the operation of the pressure spray dryer is pressed
Parameters described below：72~75 DEG C of feeding temperature, 182~185 DEG C of inlet air temperature, 79~82 DEG C of temperature of outgoing air, atomisation pressure 210~
230bar；
Further, in step (7), the temperature of dry-blending operations is 20~30 DEG C, and relative humidity is not higher than 60%R.H.
Present invention also offers the preterm formula milk powder as made from above-mentioned manufacture method.
The technical indicator of the preterm formula milk powder of the present invention is as shown in table 1 below.The technical indicator is special with reference to this area
The conventional index setting of different medical usage formula food, on this basis, adjusted further according to the nutritional need feature of premature
Protein, energy and some vitamins, the content of mineral matter.
The technical indicator of the preterm formula milk powder of the present invention of table 1
Percentage described in following embodiments is mass percent unless otherwise specified.
The source of part material is as follows in following embodiments：
Desalted whey powder：Specification D90, dimension Aktiebolaget Leo (SE) Box 941, S-251 09 Helsingborg, Sweden of Finland, raw material sources are whey.
Bis- oleic acid 2- palmitic acids of 1,3-, three ester：AAK companies of Sweden, raw material sources are palm oil.
Sunflower oil：Meet GB 10464, grain and oil (Yingkou) Co., Ltd in praising, raw material sources are sunflower seeds.
Rapeseed oil：Meet GB/T 1536-2004, grain and oil (Yingkou) Co., Ltd in praising, raw material sources are vegetable seed.
Coconut oil：Meet NY/T 230-2006, Southseas Specialty Fats Industrial (Shanghai) Co., Ltd., raw material sources are coconut.
Lactose：Food-grade, Dutch DMV companies, raw material sources are cow's milk.
Concentrated whey protein powder：Specification Alpha-10, ALAR companies of Denmark, raw material sources are whey.
Medium chain triglyceride：AAK companies of Sweden, raw material sources are palm oil.
Polyfructosan：Belgian ORAFTI companies, raw material sources are witloof.
Oligofructose：Belgian ORAFTI companies, raw material sources are witloof.
Galactooligosaccharide：Dutch DOMO companies, raw material sources are lactose.
Arachidonic acid oil：Shantou Run Ke companies, raw material sources are to split pot algae.
Docosahexaenoic acid grease：BASF Corp. of Germany, raw material sources are fish oil.
Lactoferrin：Westland companies of New Zealand, raw material sources are cow's milk.
Nucleotide：Nanjing is yeast with triumphant million industry company, raw material sources.
Multi-vitamins：Encourage into food science and technology limited company, model Li get Wei-VIT, the multi-vitamins in Shanghai
Concrete composition see the table below 2.
Composite mineral matter：Encourage into food science and technology limited company, model Li get Wei-MIN in Shanghai
Embodiment 1
The composition of raw materials of 2 embodiment 1 of table
Specific manufacture method is as follows：
(1) dispensing：Matched by said components, by desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions
It is uniformly mixed with water to being completely dissolved, the temperature of mixing is 40 DEG C, and the time of mixing is 15 minutes, feed liquid A is obtained, when material mixes
Feed order in no particular order.
(2) carburetion：Compound lard and medium chain triglyceride are first preheated to 50 DEG C, remixes 10 minutes, obtains feed liquid B.
(3) mix：The feed liquid B and feed liquid A is mixed 10 minutes, then carries out second homogenate, wherein level-one homogeneous
Pressure be 18MPa, the pressure of double-stage homogenization is 3MPa, and the temperature of homogeneous is 55 DEG C, after feed liquid C.
(4) vitamin dissolves：Multi-vitamins are dissolved in 40 DEG C of water, mixes 10 minutes, obtains feed liquid D.
(5) mineral matter dissolves：Composite mineral matter is dissolved in 40 DEG C of water, mixes 10 minutes, is added in feed liquid D, mix
Close the feed liquid E for uniformly, obtaining that solid concentration is 15.0wt%.
(6) powder processed：By the feed liquid E pasteurizes, concentrate, it is dry.Sterilization temperature is 88 DEG C, sterilizing time 25s；Concentration
Stage uses triple effect vacuum concentration process, and the solid concentration of gained concentrated milk is 48wt%；Drying stage uses pressure-type spray
Mist drying process, feeding temperature are 72 DEG C, and inlet air temperature is 182 DEG C, and temperature of outgoing air is 79 DEG C, pressure 210bar, up to half
Finished product F；
(7) it is dry-mixed：By the semi-finished product F and docosahexaenoic acid grease, arachidonic acid oil, lactoferrin, core
Thuja acid is dry-mixed, to obtain the final product.The temperature of dry-blending operations is 20 DEG C, relative humidity 55%R.H.
The product index testing result such as table 3 below of the preterm formula milk powder.
The product index testing result of 3 embodiment 1 of table
Embodiment 2
The composition of raw materials of 4 embodiment 2 of table
Specific manufacture method is as follows：
(1) dispensing：Matched by said components, by desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions
It is uniformly mixed with water to being completely dissolved, the temperature of mixing is 45 DEG C, and the time of mixing is 20 minutes, feed liquid A is obtained, when material mixes
Feed order in no particular order.
(2) carburetion：Compound lard and medium chain triglyceride are first preheated to 55 DEG C, remixes 20 minutes, obtains feed liquid B.
(3) mix：The feed liquid B and feed liquid A is mixed 20 minutes, then carries out second homogenate, wherein level-one homogeneous
Pressure be 20MPa, the pressure of double-stage homogenization is 5MPa, and the temperature of homogeneous is 60 DEG C, after feed liquid C.
(4) vitamin dissolves：Multi-vitamins are dissolved in 45 DEG C of water, mixes 15 minutes, obtains feed liquid D.
(5) mineral matter dissolves：Composite mineral matter is dissolved in 45 DEG C of water, mixes 15 minutes, is added in feed liquid D, mix
Close the feed liquid E for uniformly, obtaining that solid concentration is 17.0wt%.
(6) powder processed：By the feed liquid E pasteurizes, concentrate, it is dry.Sterilization temperature is 92 DEG C, sterilizing time 30s；Concentration
Stage uses triple effect vacuum concentration process, and the solid concentration of gained concentrated milk is 50wt%；Drying stage uses pressure-type spray
Mist drying process, feeding temperature are 75 DEG C, and inlet air temperature is 185 DEG C, and temperature of outgoing air is 82 DEG C, pressure 230bar, up to half
Finished product F；
(7) it is dry-mixed：By the semi-finished product F and docosahexaenoic acid grease, arachidonic acid oil, lactoferrin, core
Thuja acid is dry-mixed, to obtain the final product.The temperature of dry-blending operations is 30 DEG C, relative humidity 59%R.H.
The product index testing result such as table 5 below of the preterm formula milk powder.
The product index testing result of 5 embodiment 2 of table
Embodiment 3
The composition of raw materials of 6 embodiment 3 of table
Specific manufacture method is as follows：
(1) dispensing：Matched by said components, by desalted whey powder, lactose, concentrated whey protein powder, prebiotic compositions
It is uniformly mixed with water to being completely dissolved, the temperature of mixing is 42 DEG C, and the time of mixing is 18 minutes, feed liquid A is obtained, when material mixes
Feed order in no particular order.
(2) carburetion：Compound lard and medium chain triglyceride are first preheated to 53 DEG C, remixes 15 minutes, obtains feed liquid B.
(3) mix：The feed liquid B and feed liquid A is mixed 18 minutes, then carries out second homogenate, wherein level-one homogeneous
Pressure be 19MPa, the pressure of double-stage homogenization is 4MPa, and the temperature of homogeneous is 57 DEG C, after feed liquid C.
(4) vitamin dissolves：Multi-vitamins are dissolved in 42 DEG C of water, mixes 13 minutes, obtains feed liquid D.
(5) mineral matter dissolves：Composite mineral matter is dissolved in 43 DEG C of water, mixes 14 minutes, is added in feed liquid D, mix
Close the feed liquid E for uniformly, obtaining that solid concentration is 16.0wt%.
(6) powder processed：By the feed liquid E pasteurizes, concentrate, it is dry.Sterilization temperature is 90 DEG C, sterilizing time 28s；Concentration
Stage uses triple effect vacuum concentration process, and the solid concentration of gained concentrated milk is 49wt%；Drying stage uses pressure-type spray
Mist drying process, feeding temperature are 73 DEG C, and inlet air temperature is 183 DEG C, and temperature of outgoing air is 81 DEG C, pressure 220bar, up to half
Finished product F；
(7) it is dry-mixed：By the semi-finished product F and docosahexaenoic acid grease, arachidonic acid oil, lactoferrin, core
Thuja acid is dry-mixed, to obtain the final product.The temperature of dry-blending operations is 25 DEG C, relative humidity 55%R.H.
The product index testing result such as table 7 below of the preterm formula milk powder.
The product index testing result of 7 embodiment 3 of table
Comparative example 1
By taking preterm formula milk powder made from the embodiment of the present invention 1 and embodiment 3 as an example, with《National food safety standard
Special medicine purposes infant formula general rule》Premature crowd in GB 25596-2010 is reference, to embodiment 1 and in fact
Apply preterm formula milk powder nutritive index made from example 3 and carry out comparative evaluation, comparing result is as shown in table 8.
8 nutritive index of table is evaluated
As can be seen from Table 8, the preterm formula milk powder of embodiment 1 and embodiment 3 all meets《National food safety standard
Special medicine purposes infant formula general rule》Required as defined in GB 25596-2010, and the morning of embodiment 1 and embodiment 3
The contained all lactalbumins of protein in newborn baby's formula milk, wherein α-lactalbumin content is respectively 38.2% He
42.2%, the ratio that medium chain triglyceride accounts for total fat respectively is 28.1% and 23.6%, is easy to be digested and assimilated by premature, is fitted
Premature is closed to eat as single source of nutrition.The effect of embodiment 3 is suitable with embodiment 1.
Claims (10)
1. one kind drinks milk powder for premature, it is characterised in that the milk powder includes following components：Desalted whey powder 35%~
50%th, compound lard 20%~26%, lactose 5%~20%, concentrated whey protein powder 8%~12%, medium chain triglyceride 3%
~10%, prebiotic compositions 1%~3%, composite mineral matter 0.7%~0.9%, multi-vitamins 0.3%~0.4%, two
Dodecahexaene acid lipid 0.3%~0.6%, arachidonic acid oil 0.3%~0.6%, lactoferrin 0.03%~0.1%
With nucleotide 0.02%~0.05%, above-mentioned percentage accounts for the quality of milk powder percentage for each component.
2. milk powder is drunk for premature, it is characterised in that vitamin in milk powder described in per 100g according to claim 1
Species and content are：The content of vitamin A is 520~920 μ g RE；The content of vitamin D is 6.8~13.1 μ g；Vitamin E
Content be 8.2~15.6mg α-TE；Vitamin K1Content be 60~125 μ g；Vitamin B1Content be 450~1280 μ g；
Vitamin B2Content be 850~2100 μ g；Vitamin B6Content be 510~900 μ g；Vitamin B12Content for 2.3~
8.2μg；The content of niacinamide is 3000~6700 μ g；The content of folic acid is 85~235 μ g；The content of pantothenic acid is 3600~7900
μg；Ascorbic content is 100~280mg；The content of biotin is 18~55 μ g；The species and content of mineral matter element be：
The content of sodium is 125~300mg；The content of potassium is 400~950mg；The content of copper is 215~635 μ g；The content of magnesium for 32~
75mg；The content of iron is 4.9~8.6mg；The content of zinc is 2.9~6.4mg；The content of manganese is 70~380 μ g；The content of calcium is
370~780mg；The content of phosphorus is 200~500mg；The content of iodine is 76~275 μ g；The content of chlorine is 280~610mg；Selenium
Content is 17~42 μ g.
3. milk powder is drunk for premature, it is characterised in that α-breast wherein in concentrated whey protein powder according to claim 1
Albumin content >=30%.
4. drink milk powder for premature according to claim 1, it is characterised in that wherein prebiotic compositions for 40%~
The mixture of 60% polyfructosan, 20%~30% oligofructose and 20%~30% galactooligosaccharide, above-mentioned percentage are each
Component accounts for the mass percent of the prebiotic compositions.
5. milk powder is drunk for premature, it is characterised in that wherein compound lard is by 1,3-, bis- oleic acid according to claim 1
Three ester of 2- palmitic acids, sunflower oil, rapeseed oil and coconut oil composition, mass ratio are 8~10:4~6:4~6:1~2.
6. milk powder is drunk for premature, it is characterised in that the composition of the multi-vitamins includes according to claim 1
Axerophtholum aceticum, Vitamin D3, dl- α-D-α-tocopherol acetate, phytondione, thiamine hydrochloride, riboflavin, puridoxine hydrochloride,
Cyanocobalamin, niacinamide, D-VB5 calcium, L-AA and D-Biotin；The composition of composite mineral matter includes calcium carbonate, chlorination
Potassium, sodium chloride, calcium phosphate, magnesium sulfate, copper gluconate, ferrous gluconate, zinc sulfate, manganese sulfate, potassium iodide and selenous acid
Sodium.
7. a kind of prepare the method that milk powder is drunk for premature, comprise the following steps：
(1) by 35%~50% desalted whey powder, 5%~20% lactose, 8%~12% concentrated whey protein powder, 1%~3%
Prebiotic compositions and water are uniformly mixed to being completely dissolved, and obtain feed liquid A；
(2) by 20%~26% compound lard and 3%~10% medium chain triglyceride, it is uniformly mixed, obtains feed liquid B；
(3) the feed liquid B and the feed liquid A are uniformly mixed, incorporation time is 10~20 minutes, and homogeneous after mixing, obtains feed liquid
C；
(4) 0.3%~0.4% multi-vitamins and 0.7%~0.9% composite mineral matter are separately added into water and are completely dissolved
Afterwards, it is added in feed liquid C, is uniformly mixed, obtains feed liquid D, adds water to adjust the solid concentration mass percent of feed liquid D to 15.0%
~17.0%；
(5) the feed liquid D is sterilized, concentrated, it is dry, obtain semi-finished product E；By semi-finished product E and 0.3%~0.6% 22
Carbon acid grease, 0.3%~0.6% arachidonic acid oil, 0.03%~0.1% lactoferrin and 0.02%~0.05%
Nucleotide is dry-mixed, and above-mentioned percentage accounts for the quality of milk powder percentage for each component, up to the product.
8. the method that milk powder is drunk for premature is prepared according to claim 7, it is characterised in that mixing in step (2)
Temperature be 50~55 DEG C, time of mixing is 10~20 minutes.
9. the method that milk powder is drunk for premature is prepared according to claim 7, it is characterised in that described in step (3)
Homogeneous be double-stage homogenization, the wherein pressure of level-one homogeneous is 18~20MPa, and the pressure of double-stage homogenization is 3~5MPa, homogeneous temperature
Spend for 55~60 DEG C.
10. the method that milk powder is drunk for premature is prepared according to claim 7, it is characterised in that dry-mixed in step (5)
Temperature be 20~30 DEG C, relative humidity≤60%.
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| CN112741154A (en) * | 2019-10-30 | 2021-05-04 | 东北农业大学 | Formula liquid milk for premature infants and preparation method thereof |
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