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CN107823619A - A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss - Google Patents

A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss Download PDF

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Publication number
CN107823619A
CN107823619A CN201711341186.7A CN201711341186A CN107823619A CN 107823619 A CN107823619 A CN 107823619A CN 201711341186 A CN201711341186 A CN 201711341186A CN 107823619 A CN107823619 A CN 107823619A
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parts
chinese medicine
medicine composition
hair
root
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田爱莉
顾红昌
王慧
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Shaanxi Gu Sen Health Technology Co Ltd
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Shaanxi Gu Sen Health Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract

This application provides a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, include the raw medicinal material of following parts by weight:20~110 parts of gamma aminobutyric acid, 5~40 parts of ginseng, 3~40 parts of the fleece-flower root, 10~40 parts of the fruit of glossy privet, 10~55 parts of the fruit of Chinese wolfberry, 5~10 parts of cacumen biotae, 8~16 parts of mulberries, 5~35 parts of rhizoma zingiberis, 2~40 parts of the root of herbaceous peony.The Chinese medicine composition for nourishing hair tonic and Anti-hair loss that the application provides, using gamma aminobutyric acid as main component, compound other Chinese medicinal materials, start with from the root of alopecia problem, specific aim solves the problems, such as many factors for causing alopecia, hair growth comprehensive from root is realized, the effect of effectively raising alopecia, there is enriching yin and nourishing kidney, mental state of releiving, nourish the multiple efficacies such as black hair, physical fitness.With the most reparations for being directed to epidermis hair follicle of existing preparation for baldness, poor to the basic therapeutic effect of alopecia, therapeutic effect is single, cures the symptoms, not the disease and compares, there is provided based on one kind is effected a permanent cure, treats both principal and secondary aspect of disease and safe and reliable hair tonic and Anti-hair loss Chinese medicine preparation.

Description

A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss
Technical field
The present invention relates to technical field of Chinese medicine, more particularly to a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss.
Background technology
Alopecia refers to the phenomenon of epilation, and tear-away 50-70 roots hair, hair remove with beauty protection normal person daily Outside the function of scalp, also have the function that to obtain body interior important information.With the quickening pace of modern life and environment change, The phenomenon of people's alopecia is on the rise.
The symptom of alopecia is traced sth. to its source in body interior, i.e. Inner diseases are outer existing, mainly internal insufficiency of vital energy and blood, kidney in appearance The reasons such as smart virtual loss, the state of mind are excessive, depression is not understood, body is set to produce uncomfortable and symptom occur.Hair follicle work(is shown as on hair It can sustain damage, the phenomenon of epilation occurs.Especially present young man is because rhythm of life is fast, stress is big, raw Work and rest living is uncoordinated to be caused qi-blood disharmony in vivo, and body operation is not smooth, and hair follicle suffers damage, and nutrition cutout, produces large area hair Falling out.Existing preparation for baldness on the market primarily directed to hair follicle function reparation, promote hair follicle the effect of, so as to increase hair The speed of growth.It is main to include bar and apricot oil, indigo naturalis, ginger, menthol, nigella oil such as a kind of natural medicine as hair restorer Deng, by the obtained preparation for baldness such as mixing, have and nourish activation hair follicle, the effect of promoting hair regeneration.
However, reparation of the existing preparation for baldness mainly for epidermis hair follicle, its to deficiency of kidney-QI, the state of mind excessively, it is depressed not Solution etc. causes the root factor of alopecia to play good regulation and therapeutic action, it is impossible to fundamentally it treated, So as to reduce the therapeutic effect of alopecia.
The content of the invention
This application provides a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, to solve existing hair-growing and anti-hair loss product Mainly for hair follicle reparation, and it is relatively low to causing the root factors such as the deficiency of kidney-QI of alopecia, the state of mind are excessive, depression is not understood to have Regulation and therapeutic action, it is impossible to fundamentally alopecia problem is treated, reduce therapeutic effect the problem of.
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the raw material of following parts by weight Medicinal material:20~110 parts of γ-aminobutyric acid, 5~40 parts of ginseng, 3~40 parts of the fleece-flower root, 10~40 parts of the fruit of glossy privet, the fruit of Chinese wolfberry 10~ 55 parts, 5~10 parts of cacumen biotae, 8~16 parts of mulberries, 5~35 parts of rhizoma zingiberis, 2~40 parts of the root of herbaceous peony.
Optionally, the Chinese medicine composition includes the raw medicinal material of following parts by weight:50~90 parts of γ-aminobutyric acid, 15~35 parts of ginseng, 10~30 parts of the fleece-flower root, 15~30 parts of the fruit of glossy privet, 20~45 parts of the fruit of Chinese wolfberry, 6~8 parts of cacumen biotae, mulberries 10 ~14 parts, 10~30 parts of rhizoma zingiberis, 15~30 parts of the root of herbaceous peony.
Optionally, the Chinese medicine composition includes the raw medicinal material of following parts by weight:80 parts of γ-aminobutyric acid, ginseng 30 parts, 22 parts of the fleece-flower root, 24 parts of the fruit of glossy privet, 32 parts of the fruit of Chinese wolfberry, 7 parts of cacumen biotae, 12 parts of mulberries, 23 parts of rhizoma zingiberis, 22 parts of the root of herbaceous peony.
Optionally, the Chinese medicine composition also includes the raw medicinal material of following parts by weight:10~50 parts of Semen sesami nigrum, the red sage root 5~30 parts.
Optionally, the Chinese medicine composition also includes the raw medicinal material of following parts by weight:28 parts of Semen sesami nigrum, the red sage root 18 Part.
Optionally, the Chinese medicine composition is oral formulations, including excipients.
A kind of preparation method for nourishing hair tonic and Anti-hair loss traditional Chinese medicine composition, comprises the following steps:
Step 1:Raw material is weighed according to following weight parts:
20~110 parts of γ-aminobutyric acid, 5~40 parts of ginseng, 3~40 parts of the fleece-flower root, 10~40 parts of the fruit of glossy privet, the fruit of Chinese wolfberry 10~55 parts, 5~10 parts of cacumen biotae, 8~16 parts of mulberries, 5~35 parts of rhizoma zingiberis, 2~40 parts of the root of herbaceous peony;
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material;
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue;
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid;
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours;
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The technical scheme that the application provides includes following advantageous effects:
This application provides a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, using γ-aminobutyric acid as main component, Compound other Chinese medicinal materials, the Chinese medicinal material of one side γ-aminobutyric acid and compounding has the effect of enriching yin and nourishing kidney, contributes to kidney The lifting of function, and qi-deficiency kidney-deficiency is one of basic reason of alopecia problem, therefore can be solved from root most Alopecia problem.On the other hand, due to the quickening of modern life rhythm, stress increases, ponder over insomnia, it is depressed it is puzzled into For majority's alopecia the reason for, and Gabanergic supplement human body inhibitory neurotransmitter has good mental state of releiving Effect, the alopecia problem caused by pressure depression etc. can be effectively improved.
In addition, the nourishing hair tonic that the application provides and the Chinese medicinal material that the Chinese medicine composition of Anti-hair loss includes, such as The fleece-flower root, the fruit of glossy privet, cacumen biotae, mulberries etc., the effect also with growing and blacking hair, nourishing hair care, also have to treatment poliosis The effect of fine.Finally, the nourishing hair tonic and the medicinal material that includes of Chinese medicine composition of Anti-hair loss that the application provides, as rhizoma zingiberis, Root of herbaceous peony etc., also there is the effect of stimulating circulation, contribute to scalp hair follicles reparation, accelerate Hair growth rate.Taken off with existing Preparation curative effect single-phase ratio is sent out, nourishing nourishing hair tonic and the Anti-hair loss that other Chinese medicinal materials obtain are compounded using γ-aminobutyric acid Chinese medicine composition, many reasons for causing alopecia are comprehensive to solve the problems, such as alopecia, improve hair tonic and Anti-hair loss The effect of.
A kind of nourishing hair tonic and the Chinese medicine composition of Anti-hair loss that the application provides, enter from the root of alopecia problem Hand, specific aim solve the problems, such as many factors for causing alopecia, realize from the comprehensive hair growth of root, effectively carry The effect of high alopecia, there is enriching yin and nourishing kidney, mental state of releiving, nourish the multiple efficacies such as black hair, physical fitness.With existing life The most reparations for being directed to epidermis hair follicle of agent are sent out, poor to the basic therapeutic effect of alopecia, therapeutic effect is single, phase of curing the symptoms, not the disease Than, there is provided based on one kind is effected a permanent cure, treat both principal and secondary aspect of disease and safe and reliable hair tonic and Anti-hair loss Chinese medicine preparation.
Brief description of the drawings
In order to illustrate more clearly of the technical scheme of the application, letter will be made to the required accompanying drawing used in embodiment below Singly introduce, it should be apparent that, for those of ordinary skills, without having to pay creative labor, Other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the upgrowth situation of the control group and test group mouse hair in the application test case 1;
Fig. 2 is the length change of the control group and test group mouse hair in the application test case 1;
Fig. 3 is the growing state of the rear hair on probation of a female alopecia patient in the application test case 2;
Fig. 4 is the growing state of the rear hair on probation of a male pattern baldness patient in the application test case 2.
Embodiment
Accompanying drawing herein is merged in specification and forms the part of this specification, shows the implementation for meeting the application Example, and be used to together with specification to explain the principle of the application.
, below will be to embodiment or existing in order to illustrate more clearly of the embodiment of the present application or technical scheme of the prior art There is the required accompanying drawing used in technology description to be briefly described, it should be apparent that, for those of ordinary skill in the art Speech, without having to pay creative labor, other accompanying drawings can also be obtained according to these accompanying drawings.
The application provides a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, below to the property of each raw material in formula It is analyzed as follows:
γ-aminobutyric acid (GABA), it is a kind of naturally occurring non-protein composition amino acid, is distributed widely in animal and plant body It is interior, in such as Macroptilium, ginseng category, the seed of Chinese herbal medicine, rhizome and tissue fluid, and the nerve fiber of animal.Its function master To include two aspects:On the one hand, it can promote the reactivity of brain, brain tonic and intelligence development, delay brain aging function, can supplement human body suppression Nerve mediator processed, promotes sleep, beauty moisturizing, have it is good releive mental state the effect of, can be effectively improved because pressure presses down Alopecia problem caused by strongly fragrant grade.On the other hand, γ-aminobutyric acid can also promote kidney Fitness improvement and protective effect, activate liver function Can, immunologic function is adjusted, there is the effect of good to human body deficiency of kidney-QI, liver blood profit and loss etc., the kidney qi for causing alopecia can be directed to Deficiency and the problems such as feel depressed, the hair growth hair tonic problem from root.
Ginseng, sweet-bitter flavor are warm-natured, flat.Returns spleen, lung, the heart, kidney channel, gas Xiong Tirun have an invigorating qi for relieving desertion, strengthening spleen and tonifying lung, rather Heart intelligence development, the effect of nourishes blood and promotes the production of body fluid.Ginseng can medicine-food two-purpose, to adjusting the central nervous system of people, cardiac stimulant, antifatigue, regulation Metabolism etc. has obvious effect, so to a variety of for the treatment of nervous system, cardiovascular system, internal system and reproductive system Disease has good therapeutic action.It also has good tonic effect to asthenia of pulmonosplenic qi, deficiency of kidney-QI etc., is used for tonifying kidney and strengthening yang Adjust endocrine, improve impotence and premature ejaculation the problems such as.
The fleece-flower root, also known as wild seedling, hand over rattan, hand over stem, silk tree, smart, peach willow rattan, red Pueraria lobota, nine true rattans, Rui's grass, snakeweed, Chen Zhi In vain, horse hepatolith, nine true rattans, sore broom etc., it is the dried root of polygonum multiflorum thunb.Fleece-flower root sweet-bitter flavor, slightly warm in nature, enter liver, Kidney.With obvious filling liver kidney, benefiting essence-blood, strengthening the bones and muscles, black hair, calm the nerves, only juice and other effects.It is tired for the deficiency of blood, Light-headedness, body It is weak, it is sallow;Liver kidney blood and essence asthenia, dizziness and tinnitus, waist urushic acid is soft, poliosis;Hyperlipemia etc..In the present embodiment, He Shou Crow is RADIX POLYGONI MULTIFLORI PREPARATA, is mainly used in controlling blood deficiency chlorosis, nourishing liver and kidney, and tonic effect is played to the kidney blood function of taking off originator.
The fruit of glossy privet, for the fruit of the evergreen big shrub holly of Oleaceae, or the drying and ripening fruit of dungarunga platymiscium glossy privet It is real;Alias glossy privet reality, purpleflower holly fruit, wax tree, mouse Chinese catalpa, its sweet-bitter flavor is cool in nature, returns liver and kidney channel.Available for kidney tonifying enriching yin, nourishing the liver Improving eyesight, again can cardiac stimulant, strong waist and knee, nourish defaecation, crow must improving eyesight, sedation and analgesia, anti inflammation and heat resolution, Yi Yin calm the nerves, be clear weak.According to note Carry, it also has the effect of fine to the symptom such as poliosis, soreness of waist tinnitus.
The fruit of Chinese wolfberry, it is the dry mature fruit of plant of Solanaceae lycium barbarum, it is sweet, it is mild-natured, return liver and kidney channel, lung channel.Have Nourishing liver and kidney, benefiting shrewd head, moisten the effect of foster lung.For treat caused by liver and kidney deficiency, have a dizzy spell, visually unclear, soreness and weakness of waist and knees, Impotence and seminal emission, cough due to consumptive disease, quench one's thirst and draw the symptoms such as drink.The fruit of Chinese wolfberry is nourishing liver and kidney good merchantable brand, has medical experiment to show, long-term clothes It can to a certain extent be played a part of to Green Tea Extract with vitamin E-C mixture or LBP-X, make nephridial tissue MDA water It is flat to decline, prevent mitochondria aging, renal function is made moderate progress, be the good medicine for nourishing kidney qi and rare health nutrient Product.
Cacumen biotae, it is the drying branch and leaf of cupressaceae plant arbor-vitae, bitter and puckery flavor is cold in nature, return lung, liver, the spleen channel.It is mainly used in Treatment is spitted blood, bleeding from five sense organs or subcutaneous tissue, spitting of blood, is had blood in stool, metrostaxis, cough with lung heat, blood-head alopecia, poliosis.Early in ancient book《Grandson true man eat Avoid》In just on the books the method that hair do not give birth to is treated on the primary leaf in side:" cacumen biotae is dried in the shade, and makees end.It is applied with sesame oil ".Indicate The effect of cacumen biotae is to growing and blacking hair.
Mulberries, for the drying fruit ear of moraceae plants mulberry, sweet, cold in nature, the thoughts of returning home, liver and kidney channel.With liver-kidney tonifying, promote the production of body fluid Ease constipation, UFA eyesight and other effects.The Yin-nourishing and body fluid promoting that is mainly used in enriching blood is moisturized, dizziness and tinnitus palpitation and insomnia poliosis, Tianjin wound Thirsty Heat Diabetes blood deficiency and constipation etc..Mulberries can improve the blood supply of skin, especially scalp, and good blood circulation is favourable In the reparation of scalp hair follicles, the effect of promoting growing and blacking hair.
Rhizoma zingiberis, it is the dry rhizome of Zingiber herbaceos perennial ginger, acrid flavour, property is hot, returns spleen, stomach, the heart, lung channel.Mainly For treating coldness and pain in the epigastrium, vomiting, diarrhea, yang depletion is fainted inverse, and cold drink is breathed with cough, and numbness and ache of cold dampness, physically weak gas is trembled with fear, stimulated circulation With it is good the effect of, good blood circulation be advantageous to hair follicle stimulating peripheral blood running, improve hair follicle function reparation, increase The speed of growth of hair.
The root of herbaceous peony, white flower Chinese herbaceous peony is called, is Ranunculaceae Chinese herbaceous peony platymiscium, it is cool in nature, bitter acid, it is slightly cold.With nourishing blood for regulating menstruation, hold back Cloudy hidroschesis, soft liver analgesic, suppressing liver-YANG and other effects, it is anxious suitable for fever due to yin deficiency, irregular menstruation, chest and abdomen pain over the hypochondriac region, four limbs contraction, Diarrhea dysentery abdominal pain, spontaneous sweating, uterine bleeding, with inferior disease.Chinese herbaceous peony also has antipyretic, anti-inflammatory, increase coronary flow, improves cardiac muscle Nutritional blood flow, confrontation acute myocardial ischemia, suppress platelet aggregation, calmness, analgesia, spasmolysis, antiulcer, the work for adjusting blood glucose With.It also has the effect of fine in terms of antibacterial, expansion blood vessel.
Semen sesami nigrum, the black seeds of Pedaliaceae sesame, containing it is substantial amounts of fat and protein, also carbohydrate, vitamin A, The nutritional ingredients such as vitamin E, lecithin, calcium, iron, chromium.It is sweet, mild-natured, Return liver, kidney, large intestine channel.With filling liver kidney, benefiting essence-blood, Ease constipation is dry.For dizzy, Hiccough and deaf, poliosis, post disease alopecia, dry constipation of intestines and other effects.Ancient medicine and among the people Legend, which has, to be recorded, and Semen sesami nigrum is advantageous to accelerate hair tonic, and had having the effect of fine in terms of liver-kidney tonifying and blacking hair and nourishing face It is pitch-black beneficial to the nutrition for improving new piliation.
The red sage root, bitter, cold nature is nontoxic, has a promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, the effect of cool blood to disappear carbuncle. The red sage root is mainly used in chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.It is red Ginseng can be mitigated local extravasated blood, be accelerated histiocytic healing rate, effectively with the reparation and regeneration of promotion organization cell Improve blood circulation.
Embodiment 1
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the bulk drug of following parts by weight Material:20 parts of γ-aminobutyric acid, 5 parts of ginseng, 3 parts of the fleece-flower root, 10 parts of the fruit of glossy privet, 10 parts of the fruit of Chinese wolfberry, 5 parts of cacumen biotae, 8 parts of mulberries, 5 parts of rhizoma zingiberis, 2 parts of the root of herbaceous peony.
Optionally, Chinese medicine composition also includes the raw medicinal material of following parts by weight:10 parts of Semen sesami nigrum, 5 parts of the red sage root.
Optionally, Chinese medicine composition is oral formulations, including excipients.
The nourishing hair tonic and the preparation method of Anti-hair loss traditional Chinese medicine composition, comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
20 parts of γ-aminobutyric acid, 5 parts of ginseng, 3 parts of the fleece-flower root, 10 parts of the fruit of glossy privet, 10 parts of the fruit of Chinese wolfberry, 5 parts of cacumen biotae, mulberry 8 parts of Shen, 5 parts of rhizoma zingiberis, 2 parts of the root of herbaceous peony.
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material.
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue.
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid.
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours.
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is mainly used in orally, giving the user of alopecia puzzlement, daily Orally three times, it is 0.5g each taking dosage.
Embodiment 2
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the bulk drug of following parts by weight Material:50 parts of γ-aminobutyric acid, 15 parts of ginseng, 10 parts of the fleece-flower root, 15 parts of the fruit of glossy privet, 20 parts of the fruit of Chinese wolfberry, 6 parts of cacumen biotae, mulberries 10 Part, 10 parts of rhizoma zingiberis, 15 parts of the root of herbaceous peony.
Optionally, Chinese medicine composition also includes the raw medicinal material of following parts by weight:17 parts of Semen sesami nigrum, 12 parts of the red sage root.
Optionally, Chinese medicine composition is oral formulations, including excipients.
The nourishing hair tonic and the preparation method of Anti-hair loss traditional Chinese medicine composition, comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
50 parts of γ-aminobutyric acid, 15 parts of ginseng, 10 parts of the fleece-flower root, 15 parts of the fruit of glossy privet, 20 parts of the fruit of Chinese wolfberry, 6 parts of cacumen biotae, 10 parts of mulberries, 10 parts of rhizoma zingiberis, 15 parts of the root of herbaceous peony.
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material.
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue.
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid.
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours.
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is mainly used in orally, giving the user of alopecia puzzlement, daily Orally three times, it is 0.5g each taking dosage.
Embodiment 3
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the bulk drug of following parts by weight Material:80 parts of γ-aminobutyric acid, 30 parts of ginseng, 22 parts of the fleece-flower root, 24 parts of the fruit of glossy privet, 32 parts of the fruit of Chinese wolfberry, 7 parts of cacumen biotae, mulberries 12 Part, 23 parts of rhizoma zingiberis, 22 parts of the root of herbaceous peony.
Optionally, Chinese medicine composition also includes the raw medicinal material of following parts by weight:28 parts of Semen sesami nigrum, 18 parts of the red sage root.
Optionally, Chinese medicine composition is oral formulations, including excipients.
The nourishing hair tonic and the preparation method of Anti-hair loss traditional Chinese medicine composition, comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
80 parts of γ-aminobutyric acid, 30 parts of ginseng, 22 parts of the fleece-flower root, 24 parts of the fruit of glossy privet, 32 parts of the fruit of Chinese wolfberry, 7 parts of cacumen biotae, 12 parts of mulberries, 23 parts of rhizoma zingiberis, 22 parts of the root of herbaceous peony.
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material.
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue.
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid.
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours.
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is mainly used in orally, giving the user of alopecia puzzlement, daily Orally three times, it is 0.5g each taking dosage.
Embodiment 4
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the bulk drug of following parts by weight Material:90 parts of γ-aminobutyric acid, 35 parts of ginseng, 30 parts of the fleece-flower root, 30 parts of the fruit of glossy privet, 45 parts of the fruit of Chinese wolfberry, 8 parts of cacumen biotae, mulberries 14 Part, 30 parts of rhizoma zingiberis, 30 parts of the root of herbaceous peony.
Optionally, Chinese medicine composition also includes the raw medicinal material of following parts by weight:39 parts of Semen sesami nigrum, 24 parts of the red sage root.
Optionally, Chinese medicine composition is oral formulations, including excipients.
The nourishing hair tonic and the preparation method of Anti-hair loss traditional Chinese medicine composition, comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
90 parts of γ-aminobutyric acid, 35 parts of ginseng, 30 parts of the fleece-flower root, 30 parts of the fruit of glossy privet, 45 parts of the fruit of Chinese wolfberry, 8 parts of cacumen biotae, 14 parts of mulberries, 30 parts of rhizoma zingiberis, 30 parts of the root of herbaceous peony.
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material.
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue.
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid.
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours.
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is mainly used in orally, giving the user of alopecia puzzlement, daily Orally three times, it is 0.5g each taking dosage.
Embodiment 5
A kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, the Chinese medicine composition include the bulk drug of following parts by weight Material:110 parts of γ-aminobutyric acid, 40 parts of ginseng, 40 parts of the fleece-flower root, 40 parts of the fruit of glossy privet, 55 parts of the fruit of Chinese wolfberry, 10 parts of cacumen biotae, mulberries 16 parts, 35 parts of rhizoma zingiberis, 40 parts of the root of herbaceous peony.
Optionally, Chinese medicine composition also includes the raw medicinal material of following parts by weight:50 parts of Semen sesami nigrum, 30 parts of the red sage root.
Optionally, Chinese medicine composition is oral formulations, including excipients.
The nourishing hair tonic and the preparation method of Anti-hair loss traditional Chinese medicine composition, comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
110 parts of γ-aminobutyric acid, 40 parts of ginseng, 40 parts of the fleece-flower root, 40 parts of the fruit of glossy privet, 55 parts of the fruit of Chinese wolfberry, cacumen biotae 10 Part, 16 parts of mulberries, 35 parts of rhizoma zingiberis, 40 parts of the root of herbaceous peony.
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the original crushed after stirring Expect medicinal material.
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releasing filters out Liquid, remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue.
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, extracted once after decocting 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, after decocting 30min Extract again once, the filtrate after each extraction is mixed, obtain combining liquid.
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and in normal temperature Lower addition Tween 80, precipitation filtering extraction supernatant after 9 hours.
Step 6:Distilled water is added in the supernatant obtained into step 5, sterile filling bottle is added after being sterilized In, obtain Chinese medicine composition.
Optionally, the ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is mainly used in orally, giving the user of alopecia puzzlement, daily Orally three times, it is 0.5g each taking dosage.
The Chinese medicine composition of the nourishing hair tonic and Anti-hair loss is applied to mouse testing experiment and the patient that shaves one's head orally tries Test, be below the result of experiment.
Test case 1:The hair of mouse promotes growth test.
After mouse back is rejected into hair, it is divided into test group and control group, every group contains three mouse, the daily mouth of test group Take the Chinese medicine composition in embodiment 3, the water of control group oral same dose daily, persistently take one month, and to one month Mouse hair growth situation in interior test group and control group is tested, and the content of test includes observation hair growth covering feelings Condition and measure hair length.
Accompanying drawing 1 is refer to, the control group and the upgrowth situation of test group mouse hair provided the figure shows this test case.
After mouse takes the Chinese medicine composition for nourishing hair tonic and Anti-hair loss in embodiment 3 in test group, the life of its hair Long area coverage is more than control group, shows that the growing state of test group mouse hair is substantially better than control group, and test group mouse The hair color of growth is pitch-black compared with control group.
Accompanying drawing 2 is refer to, the control group and the length change of test group mouse hair provided the figure shows this test case.
The mouse hair of test group was considerably longer than control group mouse in the length of 5,10,15 days, again showed that test group is old The hair growth situation of mouse is substantially better than control group.
Shown by above-mentioned mouse result of the test, the Chinese medicine composition for nourishing hair tonic and Anti-hair loss in the present embodiment is to mouse Hair growth there is more significant facilitation, and the effect with black hair.
Test case 2:Hair loss patient oral test.
Selection 80 has the volunteer that alopecia is perplexed, and takes the Chinese medicine composition in embodiment 3, orally three times a day, often Secondary dose is 0.5g, refer to table 1, and the table show the treatment of growing and blacking hair after the Chinese medicine composition provided using the present embodiment Effect.Taking the patient cured completely for five months has 60, and effective patient has 14, and starting effective patient has 4, without obvious The patient of effect has 2, the healing efficient about 97.5% of the Chinese medicine composition of the nourishing hair tonic and Anti-hair loss.
After the Chinese medicine composition that the use the present embodiment of table 1 provides the effect of growing and blacking hair
Accompanying drawing 3 and accompanying drawing 4 are refer to, the women and a male pattern baldness patient of the offer of this test case are be provided The growing state of hair after on probation.
Hereinafter the situation of front and rear natural on-off cycles of hair growth is being used for wherein more typical 5 hair loss patients.
Mrs Gao, 35 years old, cadre did not knew alopecia the reason crown, forehead and side temple portion before half a year, and hair becomes Fine Huang, and situation is more serious (referring to accompanying drawing 3-a).After Chinese medicine composition using embodiment 3, its top head after three months Hair stopping comes off, and becomes thick black, and has kainogenesis into (referring to accompanying drawing 3-b), uses forehead and the hair at top after four, five months Become pitch-black dense (referring to accompanying drawing 3-c).
Mrs Huang, 30 years old, corporate business person, postpartum alopecia, feel depressed, have a delicate constitution, insomnia and dreamful sleep, epilation is tight Weight, and sparse jaundice.After Chinese medicine composition using embodiment 3, hair stops coming off after one month, examines it can be seen that sweat Newly sent out as hair, short kainogenesis length is begun with after three months, four, five months long hairs cover whole scalp, and the new hair grown It is pitch-black.
Mr. Wu, 45 years old, senior executive, it is often necessary to accompany client and have a meal and drink, and need overtime work of handling official business for a long time, life section Play soon, pressure is big, starts alopecia successively before 2 years, and scalp is dry to itch, and hair loss state is gradually serious, and at the top of hair and forehead takes off substantially Light (refers to accompanying drawing 4-a).Using the Chinese medicine composition of embodiment 3, its head stops itch after 15 days, hair after one and a half months Start to grow, Mood State has been lifted, after three months natural on-off cycles of hair growth gradually dense (referring to accompanying drawing 4-b), base after five months This is pitch-black dense (referring to accompanying drawing 4-c) without alopecia problem, natural on-off cycles of hair growth.
Mr. Xia, 29 years old, company clerk, frequent cold perspiration, rise often had seminal emission the year before, the phenomenon of night night sweat, and Complexion is more dim, starts alopecia before overhead half a year, and hair loss area gradually expands.Use the Chinese traditional medicine composition of embodiment 3 Thing, the crown starts to grow hair after one month, and its facial mental attitude takes a turn for the better, and no longer occurs seminal emission night sweat after three months Phenomenon, its crown alopecia position has grown dense pitch-black hair after five months.
Mr. Guo, 54 years old, worker, the disease in terms of renal function, poor appetite, dizzy, hair were once suffered from before 2 years Withered and yellow, with alopecia and dandruff, overhead hair takes off light substantially.Using the Chinese medicine composition of embodiment 3, its top after two months Hair loss area grows tiny fine hair, short black hair can be seen after four months, and body has no other uncomfortable, state of mind turn It is good.
Result of the test more than shows, the Chinese medicine composition for nourishing hair tonic and Anti-hair loss in embodiment can solution never Same sex, different age group, the alopecia of different alopecia reason patients and hair tonic problem, take can grow within four months or so it is dense Hair, and the nourishing of newborn hair quality is pitch-black, this is due to that the Chinese medicine composition is started with from the root of alopecia, targetedly solves to cause The many reasons of alopecia, kidney tonifying is nourished, adjust mental state, while stimulate blood circulation, repairing hair follicle, reach the effect treated both principal and secondary aspect of disease Fruit.
This application provides a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, using γ-aminobutyric acid as main component, Compound other Chinese medicinal materials, the Chinese medicinal material of one side γ-aminobutyric acid and compounding has the effect of enriching yin and nourishing kidney, contributes to kidney The lifting of function, and qi-deficiency kidney-deficiency is one of basic reason of alopecia problem, therefore can be solved from root most Alopecia problem.On the other hand, due to the quickening of modern life rhythm, stress increases, ponder over insomnia, it is depressed it is puzzled into For majority's alopecia the reason for, and Gabanergic supplement human body inhibitory neurotransmitter has good mental state of releiving Effect, the alopecia problem caused by pressure depression etc. can be effectively improved.
In addition, the nourishing hair tonic that the application provides and the Chinese medicinal material that the Chinese medicine composition of Anti-hair loss includes, such as The fleece-flower root, the fruit of glossy privet, cacumen biotae, mulberries etc., the effect also with growing and blacking hair, nourishing hair care, also have to treatment poliosis The effect of fine.Finally, the nourishing hair tonic and the medicinal material that includes of Chinese medicine composition of Anti-hair loss that the application provides, as rhizoma zingiberis, Root of herbaceous peony etc., also there is the effect of stimulating circulation, contribute to scalp hair follicles reparation, accelerate Hair growth rate.Taken off with existing Preparation curative effect single-phase ratio is sent out, is nourished using what γ-aminobutyric acid compounded that other Chinese medicinal materials obtain in hair tonic and Anti-hair loss Drug composition, many reasons for causing alopecia, comprehensive solves the problems, such as alopecia, improves hair tonic and the treatment of Anti-hair loss Effect.
A kind of nourishing hair tonic and the Chinese medicine composition of Anti-hair loss that the application provides, enter from the root of alopecia problem Hand, specific aim solve the problems, such as many factors for causing alopecia, realize from the comprehensive hair growth of root, effectively carry The effect of high alopecia, there is enriching yin and nourishing kidney, mental state of releiving, nourish the multiple efficacies such as black hair, physical fitness.With existing life The most reparations for being directed to epidermis hair follicle of agent are sent out, poor to the basic therapeutic effect of alopecia, therapeutic effect is single, phase of curing the symptoms, not the disease Than, there is provided based on one kind is effected a permanent cure, treat both principal and secondary aspect of disease and safe and reliable hair tonic and Anti-hair loss Chinese medicine preparation.
It should be noted that such as term " comprising ", "comprising" or its any other variant are intended to nonexcludability Include so that article or equipment including a series of elements not only include those key elements, but also including not bright The other element really listed, or also include for this process, method, article or the intrinsic key element of equipment.Do not having In the case of more limitations, the key element that is limited by sentence "including a ...", it is not excluded that the process including the key element, Other identical element in method, article or equipment also be present.
Described above is only the embodiment of the application, is made skilled artisans appreciate that or realizing this Shen Please.A variety of modifications to these embodiments will be apparent to one skilled in the art, as defined herein General Principle can be realized in other embodiments in the case where not departing from spirit herein or scope.Therefore, the application The embodiments shown herein is not intended to be limited to, and is to fit to and principles disclosed herein and features of novelty phase one The most wide scope caused.
It should be appreciated that the content that the application is not limited to be described above and is shown in the drawings, and can To carry out various modifications and changes without departing from the scope.Scope of the present application is only limited by appended claim.

Claims (8)

1. a kind of Chinese medicine composition for nourishing hair tonic and Anti-hair loss, it is characterised in that the Chinese medicine composition includes following weight The raw medicinal material of number:20~110 parts of γ-aminobutyric acid, 5~40 parts of ginseng, 3~40 parts of the fleece-flower root, 10~40 parts of the fruit of glossy privet, 10~55 parts of the fruit of Chinese wolfberry, 5~10 parts of cacumen biotae, 8~16 parts of mulberries, 5~35 parts of rhizoma zingiberis, 2~40 parts of the root of herbaceous peony.
A kind of 2. Chinese medicine composition for nourishing hair tonic and Anti-hair loss according to claim 1, it is characterised in that the Chinese medicine Composition includes the raw medicinal material of following parts by weight:50~90 parts of γ-aminobutyric acid, 15~35 parts of ginseng, the fleece-flower root 10~ 30 parts, 15~30 parts of the fruit of glossy privet, 20~45 parts of the fruit of Chinese wolfberry, 6~8 parts of cacumen biotae, 10~14 parts of mulberries, 10~30 parts of rhizoma zingiberis, in vain 15~30 parts of Chinese herbaceous peony.
A kind of 3. Chinese medicine composition for nourishing hair tonic and Anti-hair loss according to claim 1, it is characterised in that the Chinese medicine Composition includes the raw medicinal material of following parts by weight:80 parts of γ-aminobutyric acid, 30 parts of ginseng, 22 parts of the fleece-flower root, the fruit of glossy privet 24 Part, 32 parts of the fruit of Chinese wolfberry, 7 parts of cacumen biotae, 12 parts of mulberries, 23 parts of rhizoma zingiberis, 22 parts of the root of herbaceous peony.
A kind of 4. Chinese medicine composition for nourishing hair tonic and Anti-hair loss according to claim 1, it is characterised in that the Chinese medicine Composition also includes the raw medicinal material of following parts by weight:10~50 parts of Semen sesami nigrum, 5~30 parts of the red sage root.
A kind of 5. Chinese medicine composition for nourishing hair tonic and Anti-hair loss according to claim 4, it is characterised in that the Chinese medicine Composition also includes the raw medicinal material of following parts by weight:28 parts of Semen sesami nigrum, 18 parts of the red sage root.
A kind of 6. Chinese medicine composition for nourishing hair tonic and Anti-hair loss according to claim 1, it is characterised in that the Chinese medicine Composition is oral formulations, including excipients.
7. a kind of preparation method for nourishing hair tonic and Anti-hair loss traditional Chinese medicine composition, it is characterised in that comprise the following steps:
Step 1:Raw material is weighed according to following weight parts:
20~110 parts of γ-aminobutyric acid, 5~40 parts of ginseng, 3~40 parts of the fleece-flower root, 10~40 parts of the fruit of glossy privet, the fruit of Chinese wolfberry 10~ 55 parts, 5~10 parts of cacumen biotae, 8~16 parts of mulberries, 5~35 parts of rhizoma zingiberis, 2~40 parts of the root of herbaceous peony;
Step 2:The raw medicinal material that step 1 is weighed respectively carries out ultramicro grinding, the bulk drug crushed after stirring Material;
Step 3:2 times of edible soaking in alcohol is added in the crushing raw material obtained into step 2 three days, releases filter liquor, Remaining first filter residue is standby, by filter liquor after precipitation ultrafiltration, obtain filtrate and the second filter residue;
Step 4:The first filter residue obtained in step 3 and the second filter residue are added into water infusion, maintain the temperature at 80 DEG C~90 DEG C, is decocted Extracted once after boiling 40min, maintain the temperature at 90 DEG C~95 DEG C, extracted once after decocting 80 minutes, extracted again after decocting 30min Once, the filtrate after each extraction is mixed, obtains combining liquid;
Step 5:The combination liquid obtained in the filter liquor obtained in step 3, filtrate and step 4 is merged, and added at normal temperatures Enter Tween 80, precipitation filtering extraction supernatant after 9 hours;
Step 6:Distilled water is added in the supernatant obtained into step 5, adds in sterile filling bottle, obtains after being sterilized To Chinese medicine composition.
A kind of 8. preparation method for nourishing hair tonic and Anti-hair loss traditional Chinese medicine composition according to claim 7, it is characterised in that The ratio of filtrate total amount is 1 after the addition of Tween 80 and merging:90.
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CN108813246A (en) * 2018-05-31 2018-11-16 陕西顾森健康科技有限公司 A kind of easy anti-ageing composition of collagen peptide and its preparation process for absorbing Anti-lost
CN110680835A (en) * 2019-11-13 2020-01-14 江西沐恩堂生物科技有限公司 Pilatory containing earthworm extract and preparation method thereof
CN111166863A (en) * 2020-03-12 2020-05-19 乔海荣 Hair nourishing and caring traditional Chinese medicine composition and using method thereof
CN112076130A (en) * 2020-10-11 2020-12-15 广州莱约生物科技有限公司 Hair-growing and anti-hair loss composition and preparation method and application thereof
CN115137662A (en) * 2022-07-22 2022-10-04 广州洁雅日化科技有限公司 Hair-blacking and hair-nourishing composition and preparation and application thereof
CN115463204A (en) * 2022-10-19 2022-12-13 医圣堂(天津)生物科技有限公司 Traditional Chinese medicine formula for preventing alopecia and preparation method thereof

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CN106511615A (en) * 2016-11-28 2017-03-22 林少彬 Traditional Chinese medicine decoction for nourishing hair, preventing alopecia and promoting hair growth
CN107257676A (en) * 2014-12-30 2017-10-17 西蒙尼·海克 Hair Tonic or Dietary Supplement

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107257676A (en) * 2014-12-30 2017-10-17 西蒙尼·海克 Hair Tonic or Dietary Supplement
CN106511615A (en) * 2016-11-28 2017-03-22 林少彬 Traditional Chinese medicine decoction for nourishing hair, preventing alopecia and promoting hair growth

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108813246A (en) * 2018-05-31 2018-11-16 陕西顾森健康科技有限公司 A kind of easy anti-ageing composition of collagen peptide and its preparation process for absorbing Anti-lost
CN110680835A (en) * 2019-11-13 2020-01-14 江西沐恩堂生物科技有限公司 Pilatory containing earthworm extract and preparation method thereof
CN111166863A (en) * 2020-03-12 2020-05-19 乔海荣 Hair nourishing and caring traditional Chinese medicine composition and using method thereof
CN112076130A (en) * 2020-10-11 2020-12-15 广州莱约生物科技有限公司 Hair-growing and anti-hair loss composition and preparation method and application thereof
CN115137662A (en) * 2022-07-22 2022-10-04 广州洁雅日化科技有限公司 Hair-blacking and hair-nourishing composition and preparation and application thereof
CN115137662B (en) * 2022-07-22 2023-08-11 广东中科中研生物工程有限公司 Hair-blacking and developing composition and preparation and application thereof
CN115463204A (en) * 2022-10-19 2022-12-13 医圣堂(天津)生物科技有限公司 Traditional Chinese medicine formula for preventing alopecia and preparation method thereof

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