CN107260977A - A kind of brain tonic and intelligence development oral liquid and its preparation technology - Google Patents
A kind of brain tonic and intelligence development oral liquid and its preparation technology Download PDFInfo
- Publication number
- CN107260977A CN107260977A CN201710651250.5A CN201710651250A CN107260977A CN 107260977 A CN107260977 A CN 107260977A CN 201710651250 A CN201710651250 A CN 201710651250A CN 107260977 A CN107260977 A CN 107260977A
- Authority
- CN
- China
- Prior art keywords
- diacolation
- oral liquid
- diacolation solution
- solvent
- intelligence development
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims description 48
- 238000011161 development Methods 0.000 title claims description 38
- 210000004556 brain Anatomy 0.000 title claims description 37
- 230000001256 tonic effect Effects 0.000 title claims description 37
- 238000002360 preparation method Methods 0.000 title claims description 8
- 238000005516 engineering process Methods 0.000 title description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 52
- 239000002904 solvent Substances 0.000 claims description 38
- 239000003814 drug Substances 0.000 claims description 23
- 235000013399 edible fruits Nutrition 0.000 claims description 19
- 230000000694 effects Effects 0.000 claims description 19
- 230000004087 circulation Effects 0.000 claims description 18
- 238000001914 filtration Methods 0.000 claims description 15
- 240000006079 Schisandra chinensis Species 0.000 claims description 12
- 238000000605 extraction Methods 0.000 claims description 12
- 239000003755 preservative agent Substances 0.000 claims description 12
- 230000002335 preservative effect Effects 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- 235000008599 Poria cocos Nutrition 0.000 claims description 11
- 244000197580 Poria cocos Species 0.000 claims description 11
- 235000012907 honey Nutrition 0.000 claims description 11
- 241000756943 Codonopsis Species 0.000 claims description 10
- 240000008397 Ganoderma lucidum Species 0.000 claims description 9
- 238000001556 precipitation Methods 0.000 claims description 9
- 238000003860 storage Methods 0.000 claims description 9
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims description 8
- 239000009636 Huang Qi Substances 0.000 claims description 8
- 244000241872 Lycium chinense Species 0.000 claims description 8
- 235000015468 Lycium chinense Nutrition 0.000 claims description 8
- 238000004821 distillation Methods 0.000 claims description 8
- 238000011049 filling Methods 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 240000001341 Reynoutria japonica Species 0.000 claims description 6
- 235000018167 Reynoutria japonica Nutrition 0.000 claims description 6
- 230000033228 biological regulation Effects 0.000 claims description 6
- 201000010099 disease Diseases 0.000 claims description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 6
- 238000006073 displacement reaction Methods 0.000 claims description 6
- 239000000284 extract Substances 0.000 claims description 6
- 238000011068 loading method Methods 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 239000002245 particle Substances 0.000 claims description 6
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 239000012153 distilled water Substances 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 238000005259 measurement Methods 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 3
- 239000000469 ethanolic extract Substances 0.000 claims description 3
- 239000012530 fluid Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000011084 recovery Methods 0.000 claims description 3
- 238000004064 recycling Methods 0.000 claims description 3
- 238000000926 separation method Methods 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 claims description 2
- 238000009833 condensation Methods 0.000 claims description 2
- 230000005494 condensation Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000011344 liquid material Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000000935 solvent evaporation Methods 0.000 claims 1
- 230000018109 developmental process Effects 0.000 description 27
- 239000000047 product Substances 0.000 description 12
- -1 sterol ester Chemical class 0.000 description 12
- 239000002253 acid Substances 0.000 description 11
- 239000007789 gas Substances 0.000 description 10
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 8
- 150000004676 glycans Chemical class 0.000 description 8
- 229920001282 polysaccharide Polymers 0.000 description 8
- 239000005017 polysaccharide Substances 0.000 description 8
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 7
- 125000002252 acyl group Chemical group 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 230000002218 hypoglycaemic effect Effects 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 6
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 6
- 235000001014 amino acid Nutrition 0.000 description 6
- 229940024606 amino acid Drugs 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 6
- 230000003712 anti-aging effect Effects 0.000 description 6
- 230000000259 anti-tumor effect Effects 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 239000008103 glucose Substances 0.000 description 6
- 210000004185 liver Anatomy 0.000 description 6
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 5
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 5
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 5
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 5
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 5
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 5
- 235000004279 alanine Nutrition 0.000 description 5
- 150000002148 esters Chemical class 0.000 description 5
- 235000013922 glutamic acid Nutrition 0.000 description 5
- 239000004220 glutamic acid Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- 241001061264 Astragalus Species 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 4
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 4
- 235000008422 Schisandra chinensis Nutrition 0.000 description 4
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 4
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 4
- 239000004473 Threonine Substances 0.000 description 4
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 4
- 235000006533 astragalus Nutrition 0.000 description 4
- LQGUBLBATBMXHT-UHFFFAOYSA-N chrysophanol Chemical compound C1=CC=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O LQGUBLBATBMXHT-UHFFFAOYSA-N 0.000 description 4
- VEVZSMAEJFVWIL-UHFFFAOYSA-O cyanidin cation Chemical compound [O+]=1C2=CC(O)=CC(O)=C2C=C(O)C=1C1=CC=C(O)C(O)=C1 VEVZSMAEJFVWIL-UHFFFAOYSA-O 0.000 description 4
- 235000004400 serine Nutrition 0.000 description 4
- 210000004233 talus Anatomy 0.000 description 4
- 235000008521 threonine Nutrition 0.000 description 4
- 239000004474 valine Substances 0.000 description 4
- 235000014393 valine Nutrition 0.000 description 4
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 description 3
- UGMQOYZVOPASJF-OXUZYLMNSA-N Eburicoic acid Natural products C([C@@]12C)C[C@H](O)C(C)(C)[C@@H]1CCC1=C2CC[C@]2(C)[C@@H]([C@@H](CCC(=C)C(C)C)C(O)=O)CC[C@]21C UGMQOYZVOPASJF-OXUZYLMNSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 239000004471 Glycine Substances 0.000 description 3
- 208000001953 Hypotension Diseases 0.000 description 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 3
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 3
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 3
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 3
- 239000004472 Lysine Substances 0.000 description 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- 240000003152 Rhus chinensis Species 0.000 description 3
- 235000014220 Rhus chinensis Nutrition 0.000 description 3
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 3
- 235000003704 aspartic acid Nutrition 0.000 description 3
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 229960003692 gamma aminobutyric acid Drugs 0.000 description 3
- 229930182478 glucoside Natural products 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 208000021822 hypotensive Diseases 0.000 description 3
- 230000001077 hypotensive effect Effects 0.000 description 3
- 235000018977 lysine Nutrition 0.000 description 3
- 229930182817 methionine Natural products 0.000 description 3
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 3
- 235000008729 phenylalanine Nutrition 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000004224 protection Effects 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- YEFOAORQXAOVJQ-RZFZLAGVSA-N schisandrol a Chemical compound C1[C@H](C)[C@@](C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-RZFZLAGVSA-N 0.000 description 3
- DYLPEFGBWGEFBB-OSFYFWSMSA-N (+)-β-cedrene Chemical compound C1[C@]23[C@H](C)CC[C@H]3C(C)(C)[C@@H]1C(=C)CC2 DYLPEFGBWGEFBB-OSFYFWSMSA-N 0.000 description 2
- OPFTUNCRGUEPRZ-QLFBSQMISA-N (-)-beta-elemene Chemical compound CC(=C)[C@@H]1CC[C@@](C)(C=C)[C@H](C(C)=C)C1 OPFTUNCRGUEPRZ-QLFBSQMISA-N 0.000 description 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 2
- RKUNBYITZUJHSG-FXUDXRNXSA-N (S)-atropine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@H]3CC[C@@H](C2)N3C)=CC=CC=C1 RKUNBYITZUJHSG-FXUDXRNXSA-N 0.000 description 2
- SYTGUXGLBXTALU-UHFFFAOYSA-N 2h-1,4-oxazine-3-carboxylic acid Chemical compound OC(=O)C1=NC=COC1 SYTGUXGLBXTALU-UHFFFAOYSA-N 0.000 description 2
- PUQSUZTXKPLAPR-KSSYENDESA-N 4-(beta-D-Glucopyranosyloxy) benzyl alcohol Natural products O([C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1)c1ccc(CO)cc1 PUQSUZTXKPLAPR-KSSYENDESA-N 0.000 description 2
- RGHHSNMVTDWUBI-UHFFFAOYSA-N 4-hydroxybenzaldehyde Chemical compound OC1=CC=C(C=O)C=C1 RGHHSNMVTDWUBI-UHFFFAOYSA-N 0.000 description 2
- UIERETOOQGIECD-UHFFFAOYSA-N Angelic acid Natural products CC=C(C)C(O)=O UIERETOOQGIECD-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- IRAQOCYXUMOFCW-OSFYFWSMSA-N Cedr-8-ene Natural products C1[C@]23[C@H](C)CC[C@H]3C(C)(C)[C@@H]1C(C)=CC2 IRAQOCYXUMOFCW-OSFYFWSMSA-N 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- ONFPYGOMAADWAT-OXUZYLMNSA-N Dehydroeburicoic acid Chemical compound CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@@H](CCC(=C)C(C)C)C(O)=O)CC[C@@]4(C)C3=CC[C@H]21 ONFPYGOMAADWAT-OXUZYLMNSA-N 0.000 description 2
- RTZKSTLPRTWFEV-OLZOCXBDSA-N Deoxygomisin A Chemical compound COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3C[C@@H](C)[C@@H](C)CC2=CC2=C1OCO2 RTZKSTLPRTWFEV-OLZOCXBDSA-N 0.000 description 2
- UGMQOYZVOPASJF-UHFFFAOYSA-N Eburicoinsaeure Natural products CC12CCC(O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)CCC21C UGMQOYZVOPASJF-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- PUQSUZTXKPLAPR-UJPOAAIJSA-N Gastrodin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(CO)C=C1 PUQSUZTXKPLAPR-UJPOAAIJSA-N 0.000 description 2
- 229920001503 Glucan Polymers 0.000 description 2
- BFELOFVXWJZJNF-UHFFFAOYSA-N Gomisin P Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3C(O)C(C)(O)C(C)CC2=CC2=C1OCO2 BFELOFVXWJZJNF-UHFFFAOYSA-N 0.000 description 2
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 2
- RTZKSTLPRTWFEV-UHFFFAOYSA-N Isokadsuranin Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3CC(C)C(C)CC2=CC2=C1OCO2 RTZKSTLPRTWFEV-UHFFFAOYSA-N 0.000 description 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 description 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- 102000003425 Tyrosinase Human genes 0.000 description 2
- 108060008724 Tyrosinase Proteins 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- UIERETOOQGIECD-ARJAWSKDSA-N angelic acid Chemical compound C\C=C(\C)C(O)=O UIERETOOQGIECD-ARJAWSKDSA-N 0.000 description 2
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 2
- 229910017052 cobalt Inorganic materials 0.000 description 2
- 239000010941 cobalt Substances 0.000 description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 235000007336 cyanidin Nutrition 0.000 description 2
- 229960003067 cystine Drugs 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical compound O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 229930193974 gastrodin Natural products 0.000 description 2
- 150000008131 glucosides Chemical class 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- ZWRRJEICIPUPHZ-MYODQAERSA-N gomisin a Chemical compound COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3C[C@](C)(O)[C@@H](C)CC2=CC2=C1OCO2 ZWRRJEICIPUPHZ-MYODQAERSA-N 0.000 description 2
- GWDFJIBHVSYXQL-SYTFOFBDSA-N gomisin o Chemical compound COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3[C@H](O)[C@@H](C)[C@@H](C)CC2=CC2=C1OCO2 GWDFJIBHVSYXQL-SYTFOFBDSA-N 0.000 description 2
- PUQSUZTXKPLAPR-NZEXEKPDSA-N helicidol Natural products O([C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](CO)O1)c1ccc(CO)cc1 PUQSUZTXKPLAPR-NZEXEKPDSA-N 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 2
- 230000000871 hypocholesterolemic effect Effects 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 2
- 229960000310 isoleucine Drugs 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- VDYCLYGKCGVBHN-UHFFFAOYSA-N pachymaic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)C(O)CC21C VDYCLYGKCGVBHN-UHFFFAOYSA-N 0.000 description 2
- SRDNLMOBFKJOSD-UHFFFAOYSA-N pachymic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C(O)=O)C(O)CC21C SRDNLMOBFKJOSD-UHFFFAOYSA-N 0.000 description 2
- FFWOKTFYGVYKIR-UHFFFAOYSA-N physcion Chemical compound C1=C(C)C=C2C(=O)C3=CC(OC)=CC(O)=C3C(=O)C2=C1O FFWOKTFYGVYKIR-UHFFFAOYSA-N 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- BKGUPIVDQHHVMV-UHFFFAOYSA-N schisantherin C Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3C(OC(=O)C(C)=CC)C(C)(O)C(C)CC2=CC2=C1OCO2 BKGUPIVDQHHVMV-UHFFFAOYSA-N 0.000 description 2
- RODXRVNMMDRFIK-UHFFFAOYSA-N scopoletin Chemical compound C1=CC(=O)OC2=C1C=C(OC)C(O)=C2 RODXRVNMMDRFIK-UHFFFAOYSA-N 0.000 description 2
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 2
- 150000003431 steroids Chemical class 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- OGLDWXZKYODSOB-UHFFFAOYSA-N α-phellandrene Chemical compound CC(C)C1CC=C(C)C=C1 OGLDWXZKYODSOB-UHFFFAOYSA-N 0.000 description 2
- KQAZVFVOEIRWHN-UHFFFAOYSA-N α-thujene Chemical compound CC1=CCC2(C(C)C)C1C2 KQAZVFVOEIRWHN-UHFFFAOYSA-N 0.000 description 2
- FQTLCLSUCSAZDY-UHFFFAOYSA-N (+) E(S) nerolidol Natural products CC(C)=CCCC(C)=CCCC(C)(O)C=C FQTLCLSUCSAZDY-UHFFFAOYSA-N 0.000 description 1
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-3',4',5,7-Tetrahydroxy-2,3-trans-flavan-3-ol Natural products C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 1
- OPFTUNCRGUEPRZ-UHFFFAOYSA-N (+)-beta-Elemen Natural products CC(=C)C1CCC(C)(C=C)C(C(C)=C)C1 OPFTUNCRGUEPRZ-UHFFFAOYSA-N 0.000 description 1
- PADQINQHPQKXNL-LSDHHAIUSA-N (+)-dihydrokaempferol Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC=C(O)C=C1 PADQINQHPQKXNL-LSDHHAIUSA-N 0.000 description 1
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 description 1
- KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 1
- 229930013783 (-)-epicatechin Natural products 0.000 description 1
- 235000007355 (-)-epicatechin Nutrition 0.000 description 1
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 description 1
- CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 1
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- HSTZMXCBWJGKHG-UHFFFAOYSA-N (E)-piceid Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=CC(C=CC=2C=CC(O)=CC=2)=C1 HSTZMXCBWJGKHG-UHFFFAOYSA-N 0.000 description 1
- WUOACPNHFRMFPN-VIFPVBQESA-N (R)-(+)-alpha-terpineol Chemical compound CC1=CC[C@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-VIFPVBQESA-N 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- CRSBERNSMYQZNG-UHFFFAOYSA-N 1-dodecene Chemical group CCCCCCCCCCC=C CRSBERNSMYQZNG-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 1
- KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 1
- ABKPQICIFGNRAA-YCRPTBBLSA-N 5-[(e)-3-[3,5-dimethoxy-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-enoxy]-3-methyl-5-oxo-3-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoic acid Chemical compound C=1C(OC)=C(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C(OC)=CC=1\C=C\COC(=O)CC(C)(CC(O)=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ABKPQICIFGNRAA-YCRPTBBLSA-N 0.000 description 1
- HOMSOWZTBJWNHP-UHFFFAOYSA-N 5-chlorothiadiazole Chemical compound ClC1=CN=NS1 HOMSOWZTBJWNHP-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- 241000432767 Asparagus setaceus Species 0.000 description 1
- 229930003347 Atropine Natural products 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- 235000016068 Berberis vulgaris Nutrition 0.000 description 1
- 241000335053 Beta vulgaris Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000208671 Campanulaceae Species 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 1
- LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 1
- 241000614992 Codonopsis subglobosa Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 1
- ONFPYGOMAADWAT-UHFFFAOYSA-N Dehydroeburicolic acid Natural products CC1(C)C(O)CCC2(C)C3=CCC4(C)C(C(CCC(=C)C(C)C)C(O)=O)CCC4(C)C3=CCC21 ONFPYGOMAADWAT-UHFFFAOYSA-N 0.000 description 1
- ADFOLUXMYYCTRR-ZIAGYGMSSA-N Dihydroguaiaretic acid Natural products C1=C(O)C(OC)=CC(C[C@@H](C)[C@H](C)CC=2C=C(OC)C(O)=CC=2)=C1 ADFOLUXMYYCTRR-ZIAGYGMSSA-N 0.000 description 1
- XEHFSYYAGCUKEN-UHFFFAOYSA-N Dihydroscopoletin Natural products C1CC(=O)OC2=C1C=C(OC)C(O)=C2 XEHFSYYAGCUKEN-UHFFFAOYSA-N 0.000 description 1
- 239000010282 Emodin Substances 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241001289529 Fallopia multiflora Species 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- BKGUPIVDQHHVMV-LSHKVNPSSA-N Gomisin B Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3[C@H](OC(=O)C(\C)=C\C)[C@@](C)(O)[C@@H](C)CC2=CC2=C1OCO2 BKGUPIVDQHHVMV-LSHKVNPSSA-N 0.000 description 1
- BKGUPIVDQHHVMV-RZGKOBFOSA-N Gomisin B Chemical compound COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3[C@H](OC(=O)C(\C)=C/C)[C@@](C)(O)[C@@H](C)CC2=CC2=C1OCO2 BKGUPIVDQHHVMV-RZGKOBFOSA-N 0.000 description 1
- VLLFEMVDMFTBHG-UHFFFAOYSA-N Gomisin D Natural products C1C(C)C(O)(C)C2OC(=O)C(C)(O)C(C)COC3=C(OCO4)C4=CC1=C3C1=C2C=C(OC)C(OC)=C1OC VLLFEMVDMFTBHG-UHFFFAOYSA-N 0.000 description 1
- NLJJSPKWNBUDNS-MYODQAERSA-N Gomisin H Chemical compound C1[C@H](C)[C@@](C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2O NLJJSPKWNBUDNS-MYODQAERSA-N 0.000 description 1
- GWDFJIBHVSYXQL-CLUVUEOHSA-N Gomisin O Natural products O(C)c1c(OC)c2-c3c(OC)c4OCOc4cc3C[C@@H](C)[C@@H](C)[C@H](O)c2cc1OC GWDFJIBHVSYXQL-CLUVUEOHSA-N 0.000 description 1
- NLJJSPKWNBUDNS-UHFFFAOYSA-N Gomisin-H Natural products C1C(C)C(C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2O NLJJSPKWNBUDNS-UHFFFAOYSA-N 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- UGNZSMZSJYOGNX-UHFFFAOYSA-N Isoviocristine Natural products O=C1C=C(C)C(=O)C2=CC3=CC(OC)=CC(O)=C3C(O)=C21 UGNZSMZSJYOGNX-UHFFFAOYSA-N 0.000 description 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 description 1
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 description 1
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 244000241838 Lycium barbarum Species 0.000 description 1
- GQKZBCPTCWJTAS-UHFFFAOYSA-N Methyl benzyl ether Natural products COCC1=CC=CC=C1 GQKZBCPTCWJTAS-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- FQTLCLSUCSAZDY-ATGUSINASA-N Nerolidol Chemical compound CC(C)=CCC\C(C)=C\CC[C@](C)(O)C=C FQTLCLSUCSAZDY-ATGUSINASA-N 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- XACHQDDXHDTRLX-GMPBGBGESA-N Physalien Natural products O=C(O[C@H]1CC(C)(C)C(/C=C/C(=C\C=C\C(=C/C=C/C=C(\C=C\C=C(/C=C/C=2C(C)(C)C[C@H](OC(=O)CCCCCCCCCCCCCCC)CC=2C)\C)/C)\C)/C)=C(C)C1)CCCCCCCCCCCCCCC XACHQDDXHDTRLX-GMPBGBGESA-N 0.000 description 1
- HSTZMXCBWJGKHG-CENDIDJXSA-N Piceid Natural products OC[C@@H]1O[C@@H](Oc2cc(O)cc(C=Cc3ccc(O)cc3)c2)[C@H](O)[C@H](O)[C@H]1O HSTZMXCBWJGKHG-CENDIDJXSA-N 0.000 description 1
- 244000292697 Polygonum aviculare Species 0.000 description 1
- 235000006386 Polygonum aviculare Nutrition 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 244000010916 Prunus canescens Species 0.000 description 1
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 description 1
- 241000758724 Schisandraceae Species 0.000 description 1
- UFCGDBKFOKKVAC-DSASHONVSA-N Schisantherin A Chemical compound O([C@H]1C=2C=C(C(=C(OC)C=2C2=C(OC)C=3OCOC=3C=C2C[C@H](C)[C@@]1(O)C)OC)OC)C(=O)C1=CC=CC=C1 UFCGDBKFOKKVAC-DSASHONVSA-N 0.000 description 1
- UFCGDBKFOKKVAC-CEFZEKJPSA-N Schisantherin A Natural products O=C(O[C@@H]1[C@](O)(C)[C@H](C)Cc2c(c(OC)c3OCOc3c2)-c2c(OC)c(OC)c(OC)cc12)c1ccccc1 UFCGDBKFOKKVAC-CEFZEKJPSA-N 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- BKGUPIVDQHHVMV-ATODGADHSA-N Tigloylgomisin P Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3[C@@H](OC(=O)C(\C)=C/C)[C@](C)(O)[C@@H](C)CC2=CC2=C1OCO2 BKGUPIVDQHHVMV-ATODGADHSA-N 0.000 description 1
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- HTBWBWWADZJXID-TXEJJXNPSA-N Wuweizisu C Chemical compound COC1=C2C=3C(OC)=C4OCOC4=CC=3C[C@H](C)[C@H](C)CC2=CC2=C1OCO2 HTBWBWWADZJXID-TXEJJXNPSA-N 0.000 description 1
- 241001251949 Xanthium sibiricum Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- DVBSKQAFCDJNSL-QLFBSQMISA-N alpha-acoradiene Chemical compound C[C@@H]1CC[C@@H](C(C)=C)[C@@]11CC=C(C)CC1 DVBSKQAFCDJNSL-QLFBSQMISA-N 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- OGLDWXZKYODSOB-SNVBAGLBSA-N alpha-phellandrene Natural products CC(C)[C@H]1CC=C(C)C=C1 OGLDWXZKYODSOB-SNVBAGLBSA-N 0.000 description 1
- 229940037003 alum Drugs 0.000 description 1
- 230000001195 anabolic effect Effects 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- WLXGUTUUWXVZNM-UHFFFAOYSA-N anthraglycoside A Natural products C1=C(C)C=C2C(=O)C3=CC(OC)=CC(O)=C3C(=O)C2=C1OC1OC(CO)C(O)C(O)C1O WLXGUTUUWXVZNM-UHFFFAOYSA-N 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000001773 anti-convulsant effect Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002019 anti-mutation Effects 0.000 description 1
- 230000003471 anti-radiation Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 125000000089 arabinosyl group Chemical group C1([C@@H](O)[C@H](O)[C@H](O)CO1)* 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229960000396 atropine Drugs 0.000 description 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- DYLPEFGBWGEFBB-UHFFFAOYSA-N beta-Cedren Natural products C1C23C(C)CCC3C(C)(C)C1C(=C)CC2 DYLPEFGBWGEFBB-UHFFFAOYSA-N 0.000 description 1
- MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 1
- DMASLKHVQRHNES-FKKUPVFPSA-N beta-cryptoxanthin Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C DMASLKHVQRHNES-FKKUPVFPSA-N 0.000 description 1
- 229930006722 beta-pinene Natural products 0.000 description 1
- NDVASEGYNIMXJL-UHFFFAOYSA-N beta-sabinene Natural products C=C1CCC2(C(C)C)C1C2 NDVASEGYNIMXJL-UHFFFAOYSA-N 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- 229930006974 beta-terpinene Natural products 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 210000000476 body water Anatomy 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- NZPQWZZXRKZCDU-UHFFFAOYSA-N chrysophanol Natural products Cc1cc(O)c2C(=O)c3c(O)cccc3Oc2c1 NZPQWZZXRKZCDU-UHFFFAOYSA-N 0.000 description 1
- 229930016911 cinnamic acid Natural products 0.000 description 1
- 235000013985 cinnamic acid Nutrition 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical class OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000019244 cryptoxanthin Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- DVXFDXIVWQWLIU-UHFFFAOYSA-N dehydroeburiconic acid Natural products CC1(C)C(=O)CCC2(C)C3=CCC4(C)C(C(CCC(=C)C(C)C)C(O)=O)CCC4(C)C3=CCC21 DVXFDXIVWQWLIU-UHFFFAOYSA-N 0.000 description 1
- IRAQOCYXUMOFCW-UHFFFAOYSA-N di-epi-alpha-cedrene Natural products C1C23C(C)CCC3C(C)(C)C1C(C)=CC2 IRAQOCYXUMOFCW-UHFFFAOYSA-N 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- RHMXXJGYXNZAPX-UHFFFAOYSA-N emodin Chemical compound C1=C(O)C=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O RHMXXJGYXNZAPX-UHFFFAOYSA-N 0.000 description 1
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 description 1
- 235000012734 epicatechin Nutrition 0.000 description 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- HTBWBWWADZJXID-UHFFFAOYSA-N gamma-schisandrin Natural products COC1=C2C=3C(OC)=C4OCOC4=CC=3CC(C)C(C)CC2=CC2=C1OCO2 HTBWBWWADZJXID-UHFFFAOYSA-N 0.000 description 1
- XTLWNMXYCHABQH-UHFFFAOYSA-N germanicol Natural products CC1(C)CCC2(C)CCC3(C)C(CCC4(C)C5(C)CCC(O)C(C)(C)C5CCC34C)C2=C1 XTLWNMXYCHABQH-UHFFFAOYSA-N 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 125000003051 glycosyloxy group Chemical group 0.000 description 1
- PDDXWOMYBJCSQB-UHFFFAOYSA-N gomisin M2 Natural products OC1=C2C=3C(OC)=C(OC)C(OC)=CC=3CC(C)C(C)CC2=CC2=C1OCO2 PDDXWOMYBJCSQB-UHFFFAOYSA-N 0.000 description 1
- VLLFEMVDMFTBHG-SMWGPYIJSA-N gomisin d Chemical compound O([C@@H]1[C@@]([C@@H](C)C2)(C)O)C(=O)[C@](C)(O)[C@@H](C)COC3=C(OCO4)C4=CC2=C3C2=C1C=C(OC)C(OC)=C2OC VLLFEMVDMFTBHG-SMWGPYIJSA-N 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 229960003210 hyoscyamine Drugs 0.000 description 1
- 229930005342 hyoscyamine Natural products 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 229930182790 isoschizandrin Natural products 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- 229960004232 linoleic acid Drugs 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003446 memory effect Effects 0.000 description 1
- ADFOLUXMYYCTRR-OKILXGFUSA-N meso-dihydroguaiaretic acid Chemical compound C1=C(O)C(OC)=CC(C[C@H](C)[C@H](C)CC=2C=C(OC)C(O)=CC=2)=C1 ADFOLUXMYYCTRR-OKILXGFUSA-N 0.000 description 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N methanol Natural products OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 150000005217 methyl ethers Chemical class 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- POULHZVOKOAJMA-UHFFFAOYSA-N methyl undecanoic acid Natural products CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- WASNIKZYIWZQIP-AWEZNQCLSA-N nerolidol Natural products CC(=CCCC(=CCC[C@@H](O)C=C)C)C WASNIKZYIWZQIP-AWEZNQCLSA-N 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- YUPOCHDBBHTUBJ-UHFFFAOYSA-N nonadecan-10-one Chemical compound CCCCCCCCCC(=O)CCCCCCCCC YUPOCHDBBHTUBJ-UHFFFAOYSA-N 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 229940023492 oral liquid product Drugs 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000036284 oxygen consumption Effects 0.000 description 1
- 229930184989 physalin Natural products 0.000 description 1
- PKUBGLYEOAJPEG-UHFFFAOYSA-N physcion Natural products C1=C(C)C=C2C(=O)C3=CC(C)=CC(O)=C3C(=O)C2=C1O PKUBGLYEOAJPEG-UHFFFAOYSA-N 0.000 description 1
- HSTZMXCBWJGKHG-OUUBHVDSSA-N piceide Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(C=CC=2C=CC(O)=CC=2)=C1 HSTZMXCBWJGKHG-OUUBHVDSSA-N 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000021283 resveratrol Nutrition 0.000 description 1
- 229940016667 resveratrol Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- ZWRRJEICIPUPHZ-UHFFFAOYSA-N schisandrol B Natural products COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3CC(C)(O)C(C)CC2=CC2=C1OCO2 ZWRRJEICIPUPHZ-UHFFFAOYSA-N 0.000 description 1
- BKGUPIVDQHHVMV-TWJXSMCESA-N schizandrer b Chemical compound COC1=C2C=3C(OC)=C(OC)C(OC)=CC=3[C@@H](OC(=O)C(\C)=C\C)[C@](C)(O)[C@@H](C)CC2=CC2=C1OCO2 BKGUPIVDQHHVMV-TWJXSMCESA-N 0.000 description 1
- 229930193195 schizandrin Natural products 0.000 description 1
- FWYIBGHGBOVPNL-UHFFFAOYSA-N scopoletin Natural products COC=1C=C2C=CC(OC2=C(C1)O)=O FWYIBGHGBOVPNL-UHFFFAOYSA-N 0.000 description 1
- 235000015500 sitosterol Nutrition 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 1
- 229940032091 stigmasterol Drugs 0.000 description 1
- 235000016831 stigmasterol Nutrition 0.000 description 1
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- QJVXKWHHAMZTBY-GCPOEHJPSA-N syringin Chemical compound COC1=CC(\C=C\CO)=CC(OC)=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 QJVXKWHHAMZTBY-GCPOEHJPSA-N 0.000 description 1
- QJVXKWHHAMZTBY-KSXIZUIISA-N syringin Natural products COc1cc(C=CCO)cc(OC)c1O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O QJVXKWHHAMZTBY-KSXIZUIISA-N 0.000 description 1
- 239000008492 tangshen Substances 0.000 description 1
- ABKPQICIFGNRAA-MLUXTLINSA-N tangshenoside I Natural products COc1cc(C=CCOC(=O)C[C@](C)(CC(=O)O)O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)cc(OC)c1O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O ABKPQICIFGNRAA-MLUXTLINSA-N 0.000 description 1
- GGGUGZHBAOMSFJ-GADYQYKKSA-N taraxerol Chemical compound CC([C@@H]1CC2)(C)[C@@H](O)CC[C@]1(C)[C@@H]1[C@]2(C)C2=CC[C@@]3(C)CCC(C)(C)C[C@H]3[C@]2(C)CC1 GGGUGZHBAOMSFJ-GADYQYKKSA-N 0.000 description 1
- HYTFUKZLSYXRDX-UHFFFAOYSA-N taraxerol Natural products CC1CCCC2C3(C)CCC4(C)C5CC(C)(C)CCC5(C)C=CC4(C)C3C(O)CC12C HYTFUKZLSYXRDX-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- HSTZMXCBWJGKHG-CUYWLFDKSA-N trans-piceid Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=CC(\C=C\C=2C=CC(O)=CC=2)=C1 HSTZMXCBWJGKHG-CUYWLFDKSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- YEFOAORQXAOVJQ-UHFFFAOYSA-N wuweizischun A Natural products C1C(C)C(C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-UHFFFAOYSA-N 0.000 description 1
- XACHQDDXHDTRLX-HZXCUAKRSA-N zeaxanthin dipalmitate Chemical compound CC1(C)CC(OC(=O)CCCCCCCCCCCCCCC)CC(C)=C1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CC(OC(=O)CCCCCCCCCCCCCCC)CC1(C)C XACHQDDXHDTRLX-HZXCUAKRSA-N 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- WTARULDDTDQWMU-UHFFFAOYSA-N β-pinene Chemical compound C1C2C(C)(C)C1CCC2=C WTARULDDTDQWMU-UHFFFAOYSA-N 0.000 description 1
- SCWPFSIZUZUCCE-UHFFFAOYSA-N β-terpinene Chemical compound CC(C)C1=CCC(=C)CC1 SCWPFSIZUZUCCE-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A kind of brain tonic and intelligence development oral liquid of the present invention and its preparation technology, prepare canned, filling oral liquid sterilizing, label stickup and packaging multiple working procedure by the formulation of brain tonic and intelligence development oral liquid prescription, materials procurement, raw material processing, raw material tcm and herbal slice extracts active ingredients, oral liquid finished product and machine;Brain tonic and intelligence development oral liquid prescription is formulated:8 kinds of ganoderma lucidum 10,10 grams of Radix Codonopsis etc., honey and distillation water consumption, by 5: 5 volume measurements, preservative consumption 0.1%, the buying ratio of 75% alcohol solvent and tcm and herbal slice total amount is 2: 1;Raw material tcm and herbal slice extracts active ingredients, the patent of invention (July 3 2017 applying date) " medicinal herb componentses suit cylinder electric circulation automatic fitration percolating extractor " designed using the applicant, applied carries out seepage pressure effects, extract solution adds auxiliary material to be mixed evenly, carried out with 200 milliliters of volume oral liquid bottles it is canned, pack, it is oral 20 milliliters every time, twice a day.
Description
Technical field
A kind of brain tonic and intelligence development oral liquid of the present invention and its preparation technology are related to herbal health care Product processing field, especially relate to
And a kind of brain tonic and intelligence development oral liquid and its preparation technology.
Background technology
With the fast development for writing China economy, national income is continuously increased, and numerous residents are particularly middle and high income and old
The hope that year people, sub-health population pursue healthy, prevention disease, resistance aging, brain tonic and intelligence development, promotes longevity increasingly increases
It is long, be it is healthy spare no high price, in order to meet demand of the numerous residents to above-mentioned hope, present invention selection ganoderma lucidum, Radix Codonopsis, what
8 kinds of tcm and herbal slices such as the tuber of multiflower knotweed, rhizoma Gastrodiae, the Radix Astragali, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Poria cocos, are fabricated to a kind of brain tonic and intelligence development oral liquid, effect
Fruit significantly, is had complementary functions, and effect is extensive, with brain tonic and intelligence development, disease-resistant salubrity, and enhancing is immune, and anti-aging is antitumor, normal by the course for the treatment of
Drink, along with necessary physical training, adjusts psychological quality, and brain tonic and intelligence development, prevention disease can be played surely, health care of body water is improved
Flat purpose.
The content of the invention
The purpose of the present invention is, from 8 kinds of ganoderma lucidum, Radix Codonopsis, the fleece-flower root, rhizoma Gastrodiae, the Radix Astragali, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Poria cocos etc.
Tcm and herbal slice, reasonable compatibility, retrofit produces the oral liquid product of high-quality brain tonic and intelligence development, consumer is played can
The health-care effect leaned on.
To achieve these goals, the technical solution adopted by the present invention is:A kind of brain tonic and intelligence development oral liquid and its preparation work
Skill, is carried by the formulation of brain tonic and intelligence development oral liquid prescription, materials procurement, raw material processing, raw material tcm and herbal slice active ingredient
Take, oral liquid finished product is prepared canned, filling oral liquid sterilizing, label stickup and packaging multiple working procedure and machined;Brain tonic and intelligence development
Oral liquid prescription is formulated:10 grams of ganoderma lucidum, 10 grams of Radix Codonopsis, 10 grams of the fleece-flower root, 10 grams of rhizoma Gastrodiae, 10 grams of the Radix Astragali, 10 grams of the fruit of Chinese wolfberry, the five tastes
Sub 10 grams, 10 grams of Poria cocos, honey and distillation water consumption, by 5: 5 volume measurements, preservative consumption 0.1%, 75% alcohol solvent with
The ratio of tcm and herbal slice total amount is 2: 1;Materials procurement:First determine brain tonic and intelligence development oral liquid this batch produce total bottle number, it is every
Bottle capacity, production total capacity, every bottle take number of days, take total number of days, then by recipe calculation go out 8 kinds of tcm and herbal slices need daily use
Amount, graded kind is purchased, and the various tcm and herbal slices of buying have to comply with the quality index and specification of every kind of tcm and herbal slice
Standard, without going mouldy, no disease and pests harm, free from admixture, pollution-free;75% etoh solvent is purchased is with tcm and herbal slice total amount buying ratio
2∶1;Raw material are processed:In addition to honey, distilled water, preservative, every kind of tcm and herbal slice is carried out selected and dried, is sufficiently mixed
After uniform, first crushed with 6 millimeters of particle diameter pulverizers, then crush standby with 3 millimeters of particle diameter pulverizers;Raw material tcm and herbal slice has
Constituents extraction is imitated, takes ethanol extract from water precipitation to carry out, patent of invention (in the July, 2017 applying date designed using the applicant, applied
3 days) " medicinal herb componentses suit cylinder electric circulation automatic fitration percolating extractor " progress seepage pressure effects;The device is by diacolation
It is extraction element support, suit cylinder percolating device, electric pump circulatory displacement device, diacolation solution automatic filtering unit, temperature automatically controlled
Hot water circulating heating device, diacolation solvent evaporating separation device, the part of diacolation solvent condensate recycling device seven composition;The diacolation is carried
The plant operator skill flow is taken to be:1. diacolation solution control valve-→ is closed to open in charging closure-→ meter feedstock loading
Cylinder-→ layering, which is fitted into uniform-→ addition diacolation solvent of actual situation, drenches diacolation solvent-→ solvent is slowly added in circular groove-→ circular groove
It is uniform drench into raw material-→ push down circular groove should not float-→ solvent add to no longer drench into 5 centimetres away from circular groove bottom only-→ by closure
Middle part circular hole, which is rotated to drenching into circular groove inner edge-→ and open diacolation solution circulation pump-→ regulation diacolation solution circulating valve, does not make diacolation
Solution, which overflows to stop-→ close diacolation solution circulation pump-→ and close charging closure, to be penetrated screw tightening-→ to stand diacolation 36 small
When-→ open diacolation solution circulation pump circulatory displacement 36 hours-→ close diacolation solution circulation pump-→ and open the control of diacolation solution
Valve-→ diacolation solution through the screen pack automatic fitration of internal barrel bottom-→ through diacolation solution control valve-→ diacolation solution flow into evaporative cylinder
Top screen pack natural filtration-→ filtered fluid flows into diacolation solution evaporative cylinder bottom-→ and opens charging closure-→ unlatching diacolation
Solution circulation pump-→ determines whether internal barrel bottom screen pack filters terminate-→ 2. terminate filtering close diacolation solution control valve-→
New diacolation solvent-→ is added to carry out secondary cycle seepage pressure effects (operating process is identical with first time)-→ secondary cycle diacolation and carry
- → opens diacolation solution control valve-→ secondary diacolation solution through the screen pack automatic fitration of internal barrel bottom ooze by-→ inflow after the completion of taking
Solution evaporative cylinder top screen pack natural filtration-→ secondary diacolation solution of filtering flow into diacolation solution evaporative cylinder bottom-→ with first
- → 3. taking-up inner cylinder pours out dregs of a decoction cleaning-→ inner cylinder and is reentered into solution control of outer barrel-→ closing diacolation for secondary diacolation solution mixing
Valve-→ meter feedstock loads inner cylinder-→ and enters next seepage pressure effects program-→ secondary diacolation solution evaporative cylinder self-filtering net mistake
Filter terminates-→ 4. connect water source-→ to boiler, hot water storgae, condenser add water-→ open electromagnetic stove to boiler heating-→
Unlatching hot water circulating pump-→ boiler starts the cycle over-→ with hot water storgae hot water and 5. opened certainly to diacolation solution evaporative cylinder heating-→
Dynamic temperature controller-→ regulation temperature controller high temperature to 90 DEG C, low temperature to 80 DEG C-→ hot water storgae water temperature rises to 90 DEG C of electromagnetic stoves and closed automatically
Close-→ hot water storgae water temperature is down to 80 DEG C of electromagnetic stove automatic opening-→ evaporative cylinder diacolation solution solvent evaporation-→ solvents evaporation gases
Through gas delivery pipe-→ 6. gas feeding solvent gas merging chamber-→ solvent gas into spiral condensing tube be condensed into liquid-
→ liquid enters condensing solvent collecting chamber-→ inflow condensing solvent recovery cylinder-→ and is put into condensing solvent storage barrel-→ recycling
Or storage-→ 7. open diacolation solution evaporative cylinder bottom valve-→ coarse extraction medicine be put into storage barrel-→ preparation water sink agitator-
→ water sinks agitator and adds to account for the distilled water-→ for extracting medicine 60% and be slowly added to extract medicine and quickly stir-→ and stir loading
Precipitation cylinder-→ is put into 0--5 DEG C of refrigerator or freezer low-temperature precipitation-→ precipitation completion pours out supernatant-→ and obtains brain tonic and intelligence development finished product and carry
Get it filled.Brain tonic and intelligence development oral liquid finished medicines are prepared:Finished product is extracted after medicine measures by volume, is subtracted from 200 liters of oral liquid total capacity
Go, residual volume amount, honey and distillation water capacity are calculated in 5: 5 ratio, preservative is calculated by 0.1% consumption;It is standby with
300-400 rises stainless steel cylindrical vessel, and the total extraction medicine measured, lactose, distilled water, preservative are added into stainless steel cylinder holds
Device, is mixed, first stirring at low speed during stirring, and constantly regulate is to high-speed stirred, until stirring.Brain tonic and intelligence development
Oral liquid filling sterilization packaging:The oral liquid finished product stirred is added into filling apparatus, carried out orally with 200 milliliters of volumetric flasks
Liquid bottling capping, obtains brain tonic and intelligence development oral liquid finished product;By bottled oral liquid finished product through high-temperature sterilization, adhesive label, mounted box is cased,
Storage preserves sale.Brain tonic and intelligence development oral liquid is taken:Oral 20 milliliters every time, 1 twice.
According to《Chinese book on Chinese herbal medicine》Record:The beneficial effects of the invention are as follows:Above-mentioned 8 kinds of Chinese medicine prescriptions;Ganoderma lucidum is bracket fungus
The fructification of section fungi ganoderma lucidum, purple sesame etc..Contain a variety of polysaccharide effective constituents:A kind of water-soluble polysaccharide for having antitumor activity
GL-1, is that, by glucose, xylose and arabinose are constituted by mole ratio 18.8: 1.5: 1.0, and relative molecular mass is
40000.Another to have GL-B A, B, the C for having hypoglycemic activity, GL-B A peptide core content is less than 2.6%, saccharide portion system
It is made up of rhamnose, galactolipin and glucose by mole ratio 0.4: 1.0: 0.7;GL-B B Hes containing glucan 55.1%
Peptide core 44.4%, its amino acid, which is constituted, is:Glycine 13.6%, aspartic acid 12.3%, alanine 10.9%, glutamic acid
10.3%, threonine 9.4%, serine 9.1%, valine 6.6%, tyrosinase 15 .5%, leucine 4.1%, proline
4.0% and other a small amount of amino acid;Containing polysaccharide 72.5%, (wherein glucose is 69.6% to GL-B C, and 2.9%) galactolipin is
And peptide core 25.5%, its amino acid, which is constituted, is:Glycine 12.7%, alanine 12.5%, serine 11.5%, threonine
11.1%, aspartic acid 9.2%, glutamic acid 7.6%, valine 6.6%, tyrosinase 15 .5%, proline 5.2%, leucine
4.0% and other a small amount of amino acid.It is also a kind of to have promotion nucleic acid protein anabolic action, improve the polysaccharide of hematopoiesis function
BN3C, it is integral therefrom to isolate 4 kinds of polysaccharide, confirmed:BN3C1 is glucan;BN3C3 is by glucose, arabinose group
Into peptide polysaccharide, the mole ratio of glucose and arabinose is 4: 1, and the content of peptide is 5.4%, by cystine, leucine, junket
Propylhomoserin, alanine, phenylalanine, valine, glutamic acid, γ-aminobutyric acid and micro arginine, lysine, methionine, group
Propylhomoserin is constituted.GL-B, with hypoglycemic, hypocholesterolemic and antitumor action.Radix Codonopsis is often joined for Campanulaceae, element
Flower Radix Codonopsis, radix codonpsis tangshen, pipe flower Radix Codonopsis, C. subglobosa, the root of C. canescens.Containing polysaccharide [2], taraxerol, acetic acid Pu is public
English sterol ester, freidelin, stigmasterol [9], Syringin [20], tangshenoside I, (E) -2- vinyls-β-sophoroside, (E) -2- alkene
Base-α-L- mutter aralino (1 → 6)-β-D- glucopyanosides [, base-β-gentiobioside, base-β-sophoroside,
Glucopyanoside, often ginseng lactone is atractylenoide Ⅲ, codopiloic acid;And aspartic acid, threonine, serine, sweet ammonia
Acid, glutamic acid, alanine, cystine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, lysine,
The amino such as histidine, thick propylhomoserin, proline [18] and iron, copper, cobalt, MnZn, nickel, arsenic, alum, molybdenum, fluorine, etc. inorganic elements.He Shou
Crow is the root tuber of polygonum multiflorum thunb.Containing anthraquinone analog compound, main is rheum emodin, Chrysophanol and Physcion,
Rhein, chrysophanic acid anthrone.Contain stilbene compound again:Resveratrol, piceid, 4 '-tetrahydroxystilbene -2-O-D- glucose
Glucoside, 4 '-tetrahydroxystilbene -2-O- glycosides -2 "-O- gallates, "-O- does not have 4 '-tetrahydroxystilbene -2-O- glycosides -3
Infanticide acid esters.Also contain gallic acid, dextrorotation cachou extract, dextrorotation epicatechin, 3-O- nutgall acyls (-)-cachou extract, 3-O- does not have food
Sub- acyl (-)-epicatechin, 3-O- nutgall acyls original Cyanidin, 3 '-two-O- nutgall acyls original Cyanidin and cupreol,
Lecithin.Rhizoma Gastrodiae is the stem tuber of orchid rhizoma Gastrodiae.Containing gastrodin, also referred to as Gastrodin, its chemical composition is p- methylol
Benzene-β-D- glucopyanosides;The another glucoside of ether containing rhizoma Gastrodiae, its chemical composition is double-(4- acrinyls)-ether-mono--β-D- glucopyras
Glucoside.Again containing p- hydroxyphenylmethyl alcohol, p-hydroxy benzaldehyde, 4- acrinyl methyl ethers, 4- (4 '-hydroxyl benzyloxy) methyl benzyl ether,
Double (4- acrinyls) ethers, three [4- (β-D- glucopyras glycosyloxy) benzyl] citric acid esters;The Radix Astragali is legume astragalus mongolicus
Or the dry root of Astragalus membranacus.Contain 2 ', 4 ' dihydroxy -5,6- dimethoxy isoflavones, choline, beet containing Astragalus membranacus root
Alkali, amino acid, sucrose, glucuronic acid and micro folic acid, sitosterol, linoleic acid and leukotrienes and asparagine, gamma-amino
Butyric acid, astragalus polyose I, II, III, heteroglycan AH-1, AH-2, acidic polysaccharose AMon-S;The fruit of Chinese wolfberry is plant of Solanaceae lycium barbarum
Dry mature fruit.Contain glycine betaine [1], atropine, hyoscyamine [2].Again containing the yellow matter of maize, physalin [1],
Kryptoxanthin [3], Scopoletin [4], carrotene, thiamine, riboflavin, nicotinic acid, vitamin C [3].Seed contains amino acid:Asparagus fern
Propylhomoserin, proline, alanine, leucine, phenylalanine, serine, glycine, glutamic acid, cysteine, lysine, smart ammonia
Acid, isoleucine, threonine, histidine, cruel propylhomoserin, tryptophan, methionine [4].Also containing potassium, calcium, sodium, zinc, iron, copper, chromium,
The elements such as strontium, lead, nickel, cadmium, cobalt, magnesium [5].The polysaccharide of the another immunization of promotion containing tool, content is 7.09% [6].Sulphur containing ox again
Acid, tens kinds of medicinal ingredients such as γ-aminobutyric acid [7];The fruit of Chinese magnoliavine is the Schisandraceae Plant fruit of Chinese magnoliavine or the fruit of schisandra chinensis
It is real.Contain a variety of lignanoids:Gomisin A, gomisin B is schisandra chinensis ester B, and gomisin C is schisandra chinensis ester A, dagger-axe rice
Pungent F, G, schizandrin are wuweizi alcohol A, gomisin D [2], gomisin H, Radix Angelicae Sinensis acyl Ge meter Xin, crotonocyl Ge meter Xin, benzoic acid
Ge meter Xin, GJ, preceding Ge meter Xin, meso-dihydroguaiaretic acid, Biao Ge meter Xin, dextrorotation-deoxyschisandrin is five
Taste element A, GN, O, E [5], dimethyl Ge meter Xin, Gomisin P remove Radix Angelicae Sinensis acyl Ge meter Xin, left-handed-gomisin K 1 [6,
7], dextrorotation-gomisin K 2, K3 [7], tigloylgomisin P, angelic acid Gomisin P [8], Radix Angelicae Sinensis acyl Ge meter Xin Q [9], right trip-
Gomisin M2, racemic-gomisin M 1;Wuweizisu B is wuweizisu B, left trip-gomisin L 1, L2 [10], Radix Angelicae Sinensis acyl dagger-axe
Rice pungent O, the different Ge meter Xin of angelic acid, the different Gomisin O of benzoyl, Ge meter Xin R, schisandrin C, schisandra chinensis ester D [12], dagger-axe rice
Pungent S, T [3], isoschizandrin etc.;Also contain volatile oil, its composition has α-thujene, α-and a nopinene, lauro lene, α-phellandrene, β-
Terpinene, 4- terpinenols, α-terpinenol, α-(king is ancient) (king's bar) alkene, beta-elemene, acoradiene, α-and β-cedrene,
Nerolidol, furfural, 32 kinds of methyln nonyl ketone and p- isopropyl acid etc..Poria cocos is the sclerotium of On Polyporaceae Poria cocos.
Contain pachymic acid, 16 Alpha-hydroxy eburicoic acids, 24- wool steroid triolefins -21- acid, pachymic acid methyl esters, 16 Alpha-hydroxy eburicoic acid methyl esters, 9
(11)-DHPA methyl esters, and the sour methyl esters of 24 (31)-wool steroid triolefin -21- [3 β, total triterpenes methyl esters, the loose Siberian cocklebur of 3- hydrogenations
Acid, eburicoic acid, dehydroeburicoic acid, Poria cocos eo-acid, β aromadendrol acetic acid:Pachyman, Poria cocos time poly-, octanoic acid, hendecanoic acid, the moon
Cinnamic acid, lauric acid ester, palmitic acid, dodecylene acid esters, the element such as aprylic acid.Above-mentioned 8 kinds of tcm and herbal slices, have complementary functions,
Effect is extensive, and brain tonic and intelligence development is often drunk by the course for the treatment of, along with necessary physical training, adjusts psychological quality, promoting blood circulationization can be played surely
The stasis of blood, prevention disease, the purpose for improving body health level.
Present invention has the advantages that:There is ganoderma lucidum antitumor, hypoglycemic, hypocholesterolemic, coronary blood flow substantially to increase, hat
Arteries and veins vascular resistence and myocardial oxygen consumption are reduced, with antihypertensive effect, platelet aggregation-against and anti thrombotic action, hypoglycemic effect, guarantor
Liver effect, the effect of anti-oxidant, delaying senility function, antiinflammatory action, immunoregulation effect, anti-radiation;Radix Codonopsis has to be remembered to study
Recall improvement result, inhibition thrombosis, oxygen lack resistant function, resist myocardial ischemia, improve cardiovascular and cerebrovascular microcirculation, antiulcer action,
Strengthen immunization etc.;The fleece-flower root, which has, to be promoted memory effect, reducing blood lipid and anti arteriosclerosis, promotes hemoposieis, anti-blood small
The effect such as aggregation, anti-aging, enhancing be immune;There is rhizoma Gastrodiae Central nervous system to have calm, anticonvulsant action;Substantially reduction is preced with
Shape vascular resistence, increases CBF, has hypotensive, anti anoxia, promotes immunity function etc.;The Radix Astragali have anticancer, anti-aging,
Antifatigue, antiviral, antibacterium, resisting stress, hypotensive, hypoglycemic, to promote cell metabolism, protection liver kidney, enhancing immune etc. more
Plant effect;The fruit of Chinese wolfberry has antitumor, anti-mutation, anti-aging, anti-fatty liver, liver protection, reducing blood lipid, hypoglycemic, hypotensive, got rid of illness
Salubrity, the anti-ageing effect such as lengthen the life;The fruit of Chinese magnoliavine has mental-tranquilization, anti-aging, nourishing liver and kidney, protecting liver, lowering enzymes;Control neurasthenia,
Insomnia, dizziness, dim eyesight etc.;Poria cocos has mental-tranquilization, strengthening spleen and middle warmer, promote cellular immunity and humoral immune function and calmness,
The effect such as antibacterial, hypoglycemic, protection liver, antitumor.
Embodiment
Specific embodiment:
1st, formulating brain tonic and intelligence development oral liquid prescription is:Ganoderma lucidum 10,10 grams of Radix Codonopsis, 10 grams of the fleece-flower root, 10 grams of rhizoma Gastrodiae, the Radix Astragali 10
Gram, 10 grams of the fruit of Chinese wolfberry, 10 grams of the fruit of Chinese magnoliavine, 10 grams of Poria cocos, honey with distillation water consumption, by 5: 5 volume measurements, preservative consumption
0.1%.
2nd, it is 1000 bottles to determine this batch brain tonic and intelligence development oral liquid output, and per bottled 200 milliliters, oral liquid need to be prepared altogether
Total amount is 200 liters.
3rd, tcm and herbal slice total amount is 400 kilograms needed for being calculated by this batch brain tonic and intelligence development oral liquid output, by formula
Ratio calculates 8 kinds of tcm and herbal slice amount of purchases:50 kilograms of ganoderma lucidum, 50 kilograms of Radix Codonopsis, 50 kilograms of the fleece-flower root, rhizoma Gastrodiae 50
Kilogram, 50 kilograms of the Radix Astragali, 50 kilograms of the fruit of Chinese wolfberry, 50 kilograms of the fruit of Chinese magnoliavine, 50 kilograms of Poria cocos, honey with distillation water consumption, by 5: 5 hold
Product metering, preservative consumption 0.1%, 75% alcohol solvent purchases 800 liters, recycles.
4th, tcm and herbal slice is processed:Every kind of tcm and herbal slice is carried out selected and dried, after being sufficiently mixed uniformly, first with 6
Millimeter particle diameter pulverizer is crushed, then crushes standby with 3 millimeters of particle diameter pulverizers.
5th, tcm and herbal slice extracts active ingredients:Ethanol extract from water precipitation is taken to carry out, the hair designed using the applicant, applied
Bright patent (July 3 2017 applying date) " medicinal herb componentses suit cylinder electric circulation automatic fitration percolating extractor " is entered
Row seepage pressure effects;The device is molten by percolating extractor support, suit cylinder percolating device, electric pump circulatory displacement device, diacolation
Liquid automatic filtering unit, temperature automatically controlled hot water circulating heating device, diacolation solvent evaporating separation device, the condensation of diacolation solvent are reclaimed
The part of device seven is constituted;The percolating extractor operation technological process is:1. closing diacolation solution control valve-→, it is close to open charging
- → layering that capping-→ meter feedstock is fitted into inner cylinder, which is fitted into actual situation uniform-→ and adds diacolation solvent, drenches slow in circular groove-→ circular groove
It is slow add diacolation solvent-→ solvent uniformly drench into raw material-→ push down circular groove should not float-→ solvent adds to and no longer drenches into away from circular groove
Only circular hole in the middle part of closure is rotated to drenching into circular groove inner edge-→ and open diacolation solution circulation pump-→ regulation and oozed by-→ for 5 centimetres of bottom
Solution circulating valve of filtering does not make diacolation solution spilling, and only-→ closing diacolation solution circulation pump-→ closing charging closure penetrates screw
Tighten-→ and stand-→ the closing diacolation solution circulation in 36 hours of diacolation 36 hours-→ unlatching diacolation solution circulation pump circulatory displacement
Through the screen pack automatic fitration of internal barrel bottom ,-→ controls pump-→ opening diacolation solution control valve-→ diacolation solution through diacolation solution
Valve-→ diacolation solution flows into evaporative cylinder top screen pack natural filtration-→ filtered fluid inflow diacolation solution evaporative cylinder bottom-→ and beaten
Opening charging closure ,-→ opens diacolation solution circulation pump-→ and determines whether internal barrel bottom screen pack filters and terminate-→ and 2. terminated
Filter and close diacolation solution control valve-→ addition new diacolation solvent-→ progress secondary cycle seepage pressure effects (operating process and first time
It is identical) after the completion of-→ secondary cycle seepage pressure effects-→ open diacolation solution control valve-→ secondary diacolation solution through internal barrel bottom
Screen pack automatic fitration-→ flows into diacolation solution evaporative cylinder top screen pack natural filtration-→ secondary diacolation solution and flows into diacolation
Solution evaporative cylinder bottom-→ with first time diacolation solution mix-→, which 3. takes out inner cylinder and pours out dregs of a decoction cleaning-→ inner cylinder, to be reentered into
Outer barrel-→ closes diacolation solution control valve-→ meter feedstock and loads inner cylinder-→ and enter next seepage pressure effects program that-→ secondary oozes
Solution evaporative cylinder self-filtering net filtration of filtering terminates-→ 4. connect water source-→ added water to boiler, hot water storgae, condenser-→ open
Open electromagnetic stove to boiler heat-→ open hot water circulating pump-→ boiler and hot water storgae hot water start the cycle over-→ it is molten to diacolation
Automatic temperature control instrument-→ regulation temperature controller high temperature to 90 DEG C, low temperature to 80 DEG C-→ hot water storgae water is 5. opened in liquid evaporative cylinder heating-→
Temperature rise to 90 DEG C of electromagnetic stoves close automatically-and → hot water storgae water temperature is down to 80 DEG C of electromagnetic stove automatic opening-→ evaporative cylinder diacolation solution
Solvent evaporation-→ solvent evaporate gas through gas delivery pipe-→ 6. gas feeding solvent gas merging chamber-→ solvent gas enter
Spiral condensing tube is condensed into liquid-→ liquid and flows into condensing solvent recovery cylinder-→ into condensing solvent collecting chamber-→ and be put into cold
Solidifying solvent storage barrel-→ recycles or storage-→ and 7. opens diacolation solution evaporative cylinder bottom valve-→ coarse extraction medicine and be put into and deposit
Storage cylinder-→ preparation water sink agitator-→ water sink agitator add account for extract medicine 60% distilled water-→ be slowly added to extract medicine it is fast
Speed stirring-→ the loading precipitation cylinder-→ that stirs is put into 0--5 DEG C of refrigerator or freezer low-temperature precipitation-→ precipitation completion and pours out supernatant
Liquid-→ obtains brain tonic and intelligence development finished product and extracts medicine.
6th, brain tonic and intelligence development oral liquid finished medicines are prepared:After total extraction medicine is measured by volume, from 200 liters of oral liquid total capacity
Subtract, residual capacity, honey and distillation water capacity are calculated in 5: 5 ratio, preservative is calculated by 0.1% consumption;It is standby with
300-400 rises stainless steel cylindrical vessel, and the total extraction medicine measured, honey 0000, distilled water, preservative are added into stainless steel circle
Cylinder container, is mixed, first stirring at low speed during stirring, and constantly regulate is to high-speed stirred, until stirring.
7th, brain tonic and intelligence development oral liquid filling sterilization packaging:The oral liquid finished product stirred is added into filling apparatus, with 200
Milliliter volumetric flask carries out oral liquid bottling capping promoting blood circulation and removing blood stasis;Obtain oral liquid finished product promoting blood circulation and removing blood stasis;Bottled brain tonic and intelligence development is oral
Liquid finished product preserves sale through high-temperature sterilization, adhesive label, mounted box vanning, storage.
8th, brain tonic and intelligence development oral liquid is taken:Oral 20 milliliters every time, 1 twice.
Claims (7)
1. brain tonic and intelligence development oral liquid prescription, it is characterized in that:Ganoderma lucidum 10,10 grams of Radix Codonopsis, 10 grams of the fleece-flower root, 10 grams of rhizoma Gastrodiae, the Radix Astragali 10
Gram, 10 grams of the fruit of Chinese wolfberry, 10 grams of the fruit of Chinese magnoliavine, 10 grams of Poria cocos, honey with distillation water consumption, by 5: 5 volume measurements, preservative consumption
0.1%.
2. brain tonic and intelligence development oral liquid materials procurement;It is characterized in that:Brain tonic and intelligence development oral liquid output is first determined, then based on formula
The amount of purchase for calculating every kind of tcm and herbal slice is purchased, and the various tcm and herbal slices of buying have to comply with every kind of tcm and herbal slice
Quality index and specification standards, without going mouldy, no disease and pests harm, free from admixture, pollution-free;75% etoh solvent is purchased to be drunk with Chinese medicine
Piece total amount buying ratio is 2: 1.
3. brain tonic and intelligence development oral liquid raw material are processed:It is characterized in that:In addition to honey, distilled water, preservative, every kind of Chinese medicine is drunk
Piece is carried out selected and dried, be sufficiently mixed it is uniform after, first with 6 millimeters of particle diameter pulverizers crushing, then with 3 millimeters of particle diameter pulverizer powder
It is broken standby.
4. brain tonic and intelligence development oral liquid tcm and herbal slice extracts active ingredients:It is characterized in that:Ethanol extract from water precipitation is taken to carry out, using this
" medicinal herb componentses suit cylinder electric circulation is automatic for applicant's design, the patent of invention (July 3 2017 applying date) of application
Filter percolating extractor " carry out seepage pressure effects;The device is by percolating extractor support, suit cylinder percolating device, electric pump
Circulatory displacement device, diacolation solution automatic filtering unit, temperature automatically controlled hot water circulating heating device, diacolation solvent evaporation separation dress
Put, the part of diacolation solvent condensate recycling device seven is constituted;The percolating extractor operation technological process is:1. diacolation solution is closed
Control valve-→ opens charging closure-→ meter feedstock loading inner cylinder-→ layering loading actual situation uniform-→ and adds diacolation solvent
Drench be slowly added in circular groove-→ circular groove diacolation solvent-→ solvent uniformly drench into raw material-→ push down circular groove should not float-→ it is molten
Agent, which is added to, no longer drenches into 5 centimetres away from circular groove bottom only-→ and rotates circular hole in the middle part of closure to drenching into circular groove inner edge-→ and open diacolation
Solution circulation pump-→ regulation diacolation solution circulating valve does not make diacolation solution overflow only-→ closing diacolation solution circulation pump-→ closing
Charging closure penetrate screw tightening-→ stand diacolation 36 hours-→ open diacolation solution circulation pump circulatory displacement 36 hours-→
Close diacolation solution circulation pump-→ open diacolation solution control valve-→ diacolation solution through the screen pack automatic fitration of internal barrel bottom-→
- → diacolation solution inflow evaporative cylinder top screen pack natural filtration-→ filtered fluid inflow diacolation solution through diacolation solution control valve
Open charging closure-→ and open diacolation solution circulation pump-→ and determine whether internal barrel bottom screen pack filters in evaporative cylinder bottom-→
Terminate-→ and 2. terminate filtering closing diacolation solution control valve-→ addition new diacolation solvent-→ progress secondary cycle seepage pressure effects
- → opens diacolation solution control valve-→ secondary oozes after the completion of (operating process is identical with first time)-→ secondary cycle seepage pressure effects
Solution of filtering through the screen pack automatic fitration of internal barrel bottom-→ flow into the top screen pack natural filtration of diacolation solution evaporative cylinder-→ it is secondary
Diacolation solution flow into diacolation solution evaporative cylinder bottom-→ mixed with first time diacolation solution-→ 3. taking-up inner cylinder to pour out the dregs of a decoction clear
Wash-→ inner cylinder is reentered into outer barrel-→ closes diacolation solution control valve-→ meter feedstock and load inner cylinder-→ and enter next diacolation
Extraction procedure-→ secondary diacolation solution evaporative cylinder self-filtering net filtration terminate-→ 4. connect water source-→ to boiler, hot water
Groove, condenser add water-→ unlatching electromagnetic stove to boiler heating-→ unlatching hot water circulating pump-→ boiler and hot water storgae hot water
Start the cycle over-→ to diacolation solution evaporative cylinder heating-→ 5. open automatic temperature control instrument-→ regulation temperature controller high temperature to 90 DEG C, it is low
Temperature to 80 DEG C-→ hot water storgae water temperature rise to 90 DEG C of electromagnetic stoves close automatically-→ hot water storgae water temperature is down to 80 DEG C of electromagnetic stoves and opens automatically
Open-→ evaporative cylinder diacolation solution solvent evaporation-→ solvent evaporate gas through gas delivery pipe-→ 6. gas feeding solvent gas converge
Collection room-→ solvent gas is condensed into liquid-→ liquid into condensing solvent collecting chamber-→ inflow condensation into spiral condensing tube
Solvent recovery cylinder-→ is put into condensing solvent storage barrel-→ and recycles or store-→ 7. unlatching diacolation solution evaporative cylinder lower valve
Door-→ coarse extraction medicine is put into storage barrel-→ heavy agitator of the heavy agitator-→ water of preparation water and adds the distillation for accounting for and extracting medicine 60%
Water-→, which is slowly added to extract medicine and quickly stirs-→, stirs that to be put into 0--5 DEG C of refrigerator or freezer low temperature heavy for loading precipitation cylinder-→
Shallow lake-→ precipitation completion pours out supernatant-→ and obtains brain tonic and intelligence development finished product extraction medicine.
5. brain tonic and intelligence development oral liquid finished medicines are prepared;It is characterized in that:After total extraction medicine is measured by volume, from oral liquid total measurement (volume) amount
Subtracted in 200 liters, residual volume amount, honey and distillation water capacity are calculated in 5: 5 ratio, preservative uses gauge by 0.1%
Calculate;It is standby that stainless steel cylindrical vessel is risen with 300-400, the total extraction medicine measured, honey, distilled water, preservative are added stainless
Steel cylindrical vessel, is mixed, first stirring at low speed during stirring, and constantly regulate is to high-speed stirred, until stirring.
6. brain tonic and intelligence development oral liquid filling sterilization packaging;It is characterized in that:The oral liquid finished product stirred is added into filling apparatus,
Oral liquid bottling capping is carried out with 200 milliliters of volumetric flasks;Obtain brain tonic and intelligence development oral liquid finished product;By bottled oral liquid finished product through high temperature
Sterilizing, adhesive label, mounted box vanning, storage preserves sale.
7. brain tonic and intelligence development oral liquid is taken;It is characterized in that:Oral 20 milliliters every time, 1 twice.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710651250.5A CN107260977A (en) | 2017-07-23 | 2017-07-23 | A kind of brain tonic and intelligence development oral liquid and its preparation technology |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710651250.5A CN107260977A (en) | 2017-07-23 | 2017-07-23 | A kind of brain tonic and intelligence development oral liquid and its preparation technology |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107260977A true CN107260977A (en) | 2017-10-20 |
Family
ID=60076200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710651250.5A Pending CN107260977A (en) | 2017-07-23 | 2017-07-23 | A kind of brain tonic and intelligence development oral liquid and its preparation technology |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107260977A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115120677A (en) * | 2022-07-16 | 2022-09-30 | 陕西康惠制药股份有限公司 | Traditional Chinese medicine composition for tonifying kidney and soothing nerves and preparation method thereof |
CN115120678A (en) * | 2022-07-16 | 2022-09-30 | 陕西康惠制药股份有限公司 | Traditional Chinese medicine composition for treating neurasthenia, insomnia and dreaminess and preparation method thereof |
CN116350719A (en) * | 2023-05-22 | 2023-06-30 | 绵阳一康制药有限公司 | A kind of preparation method of compound Gastrodia elata granule |
-
2017
- 2017-07-23 CN CN201710651250.5A patent/CN107260977A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115120677A (en) * | 2022-07-16 | 2022-09-30 | 陕西康惠制药股份有限公司 | Traditional Chinese medicine composition for tonifying kidney and soothing nerves and preparation method thereof |
CN115120678A (en) * | 2022-07-16 | 2022-09-30 | 陕西康惠制药股份有限公司 | Traditional Chinese medicine composition for treating neurasthenia, insomnia and dreaminess and preparation method thereof |
CN115120678B (en) * | 2022-07-16 | 2023-05-26 | 陕西康惠制药股份有限公司 | Preparation method of traditional Chinese medicine composition for neurasthenia, insomnia and dreaminess |
CN115120677B (en) * | 2022-07-16 | 2023-05-26 | 陕西康惠制药股份有限公司 | Traditional Chinese medicine composition for tonifying kidney and soothing nerves and preparation method thereof |
CN116350719A (en) * | 2023-05-22 | 2023-06-30 | 绵阳一康制药有限公司 | A kind of preparation method of compound Gastrodia elata granule |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101199595A (en) | Extractive process of baical skullcap root active ingredient | |
CN102630776A (en) | Ginkgo leaf extracting technology and ginkgo black tea processing method | |
CN104286256A (en) | Pilose asiabell root and membranous milkvetch root health-preserving traditional Chinese medicine tea drink and preparation method thereof | |
CN107260977A (en) | A kind of brain tonic and intelligence development oral liquid and its preparation technology | |
CN107348090A (en) | A kind of ginseng sugar of health kidney tonifying and preparation method thereof | |
CN1973885A (en) | Shenjing capsule and shenjing oral liquid | |
CN105733809A (en) | Method and equipment for producing jasmine hydrolat through low temperature distillation | |
CN102488048A (en) | Jujube rind tea and preparation method for drink thereof | |
CN107260842A (en) | A kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata and its preparation technology | |
CN117680038B (en) | Plant raw juice extraction equipment based on microwave heating and process thereof | |
CN102138956A (en) | Health-care product having liver-protecting function and production process | |
CN104666928A (en) | Preparation method of rapid decoction piece of dendrobium officinale and chrysanthemum | |
CN112546148A (en) | Traditional Chinese medicine formula for treating chronic heart failure and preparation method thereof | |
CN107441449A (en) | A kind of oral liquid promoting blood circulation and removing blood stasis and its preparation technology | |
CN101928658B (en) | Method for producing acanthopanax bark wine by traditional Chinese medicine steam extraction method | |
CN104524237B (en) | HERBA DENDROBII soft capsule and preparation method thereof | |
CN107998276A (en) | A kind of Changchun Bao oral liquid and preparation method thereof | |
CN107260817A (en) | A kind of hypotensive oral liquid and its preparation technology | |
CN102626156A (en) | Ginkgo leaf extraction process and method for processing fermented ginkgo Pu'er tea | |
CN106266026A (en) | A kind of curcumin composition of Antialcoholic liver-protecting | |
CN101928660B (en) | Method for producing cortex acanthopanacis spirits by Chinese medicinal material fluid extract method | |
CN107375468A (en) | A kind of compound astragalus membranaceus bighead atractylodes rhizome anti-lung cancer oral liquid and its preparation technology | |
CN107349309A (en) | A kind of compound bavin head red sage root anti-liver cancer and anti-oral liquids and its preparation technology | |
CN107375691A (en) | A kind of fat reducing and weight reducing oral liquor and its preparation technology | |
CN112076278A (en) | Underground health-preserving seedling medicine menstruation formula and preparation process thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171020 |