CN107259141A - The feed addictive and its making application method of a kind of in-pig - Google Patents
The feed addictive and its making application method of a kind of in-pig Download PDFInfo
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- CN107259141A CN107259141A CN201710511498.1A CN201710511498A CN107259141A CN 107259141 A CN107259141 A CN 107259141A CN 201710511498 A CN201710511498 A CN 201710511498A CN 107259141 A CN107259141 A CN 107259141A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
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Abstract
The invention discloses a kind of feed addictive of in-pig and its making application method.The additive is using 1,2, No. 3 each 1 part of material mix after according to 10:1 weight ratio is mixed with yeast cell wall polysaccharide and obtained；Wherein No. 1 material is made up of 50 parts of Lactobacillus plantarum metabolite antibacterial peptide, 50 parts of Lactobacillus rhamnosus；No. 2 material are made up of 20 parts of 20 parts of glucose oxidase, 20 parts of catalase, 20 parts of peptase of victory, 20 parts of epoxidoreductase and phosphate；No. 3 material are made up of calcareous 50 parts of montmorillonite, 15 parts of gypsum, 15 parts of glauber salt, 20 parts of sodium bicarbonate.Product of the present invention is added in sow feed in 90 days phase of parturition of sow gestation by 2 kg/ton.Product of the present invention can effectively prevent the influence of mycotoxin and vivotoxin to in-pig, and number born of sow and strong young number are significantly improved, and time interval of being farrowed during Farrowing substantially shortens, and sow premunition is obviously improved, and sow reproductive performance is significantly improved.
Description
Technical field
It is particularly a kind of to be applied to in-pig (pregnant 90 days-phase of parturition) the present invention relates to a kind of feed addictive
Removing toxic substances, de- mould, detoxification, the feed addictive of anti-inflammatory and its making application method.
Background technology
Mycotoxin contamination, it has also become a big harm of influence world agriculture, feed industry and aquaculture development.How to recognize
Can then turn into prevention and control mycotoxin solve the matter of utmost importance of feed safety and livestock product safety.Mould and its toxin not only drop
The nutritive value and palatability of low feed, influence the storing of feed with using, more seriously destroy Immune Function In Animals and machine
Body Redox homeostasis, reduction animal disease resistant power and the general level of the health, and then reduce breeding performonce fo animals, waste feed resource.And
The acute and chronic poisoning of animal different symptoms can be caused, the health of animal, or even life is endangered, the influence especially to pig is maximum.
Mycotoxin is a kind of ANFs existed in feed and raw material, is the very strong mould secondary metabolism production of toxin
Thing.Mycotoxin can be all produced in the processing, transport and storage process of feed.Mycotoxins in feed generally existing, and plant
Class has as many as tens kinds.Such as aspergillus flavus have very strong carcinogenicity, the liver of chief destructive animal；Zeranol, it is similar female
Functions of hormones, destroys the reproductive organs of animal；T-2 toxin destroys animal immune organ, and vomitoxin influences the appetite of pig, right
Digestive organs cause damage.Meanwhile, the antibiotic and antibiosis added in animal body in the biogenic amine of eubolism generation, feed
Element kill the poisonous and harmful substance such as endotoxin for producing after enteric bacteria be difficult to be decomposed in liver completely conversion detoxification when, directly
Tap into and cause animal normal physiological in disorder into blood.Sow stages of gestation be both faced with environment stress with it is all in feed
Many deterrents, especially after gestation 90 days, fetal growth is rapid, and the 3/4 of its body weight completes in this stage, the excretion of fetus
Thing weightening sow liver renal excretion burden, cause when serious sow hepatic and renal function be damaged, often occur in practice Sow abortion, extremely
Tire, stages of labor be long, difficult labour, lochia is lasting, postpartum tired paralysis is slept, appetite disorder, feed intake is low, milk is not enough, piglet milk supply
The symptoms such as diarrhoea, inter oestrual period extension.At present, prevent above disease or phenomenon from occurring, be commonly in sow diets and add mould
Endotoxin adsorbent, can reach the effect of alleviation to a certain extent.But the mold toxin sorbent of market is main with physical absorption
Based on agent, the mycotoxin in adsorption feed simultaneously also seeks a large amount of vitamins (especially liposoluble vitamin), trace element etc.
Form point absorption exclude it is external, while effectively absorption not fully, and to having there is the swinery of mycotoxicosis and invalid,
Endotoxin (such as lipopolysaccharides LPS) can't be adsorbed in addition and the toxin being absorbed into blood of degrading, do not reach real detoxification, solution
Poison, detoxification, the purpose and effect of toxin expelling.Based on this, necessary exploitation is a kind of to be applied to in-pig (90 days-childbirth of gestation
Stage) detoxify, de- mould, detoxification, the feedstuff additive product of anti-inflammatory.
The content of the invention
The technical problem to be solved in the present invention is, for produced problem in current sow cultivating link and the disease often occurred
Disease, the present invention provides feed addictive of a kind of in-pig (pregnant 90 days-phase of parturition) and preparation method thereof, with thorough
The internal a variety of toxin of exclusion, strengthen sow immunity, improve sow number born alive, improve the nascent counterpoise of piglet.
In order to solve the above technical problems, the technical solution adopted in the present invention is:A kind of in-pig (pregnant 90 days-point
The childbirth stage) feed addictive, in parts by weight using No. 1 material, No. 2 material, No. 3 material it is each 1 part mix after according to 10:1
Weight ratio and yeast cell wall polysaccharide mix and obtain.Wherein No. 1 material by Lactobacillus plantarum metabolite antibacterial peptide (potency >=
104U/g) 50 parts, Lactobacillus rhamnosus (content >=107CFU/g) 50 parts of compositions；No. 2 material are by glucose oxidase (enzyme activity content
>=1000U/g) 20 parts, 20 parts of catalase (enzyme activity content >=1000U/g), victory peptase (enzyme activity content >=1000U/g) 20
Part, 20 parts of epoxidoreductase (enzyme activity content >=1000U/g), 20 parts of compositions of phosphate (enzyme activity content >=10000U/g)；3
Number material is by containing cat's eye more than 5% and bright by 50 parts of the calcareous montmorillonite of 380 DEG C of high-temperature calcinations expansion, 15 parts of gypsum, member
15 parts of powder, 20 parts of compositions of sodium bicarbonate.
Specific process of the invention is operated according to the following steps：
1) Lactobacillus plantarum metabolite antibacterial peptide (potency >=10 are taken4U/g) 50 parts, Lactobacillus rhamnosus (content >=
107CFU/g) 50 parts, mix, control moisture is no more than 10%, be used as No. 1 material；
2) 20 parts of glucose oxidase (enzyme activity content >=1000U/g), catalase (enzyme activity content >=1000U/g) are taken
20 parts, victory peptase 20 parts of (enzyme activity content >=1000U/g), 20 parts of epoxidoreductase (enzyme activity content >=1000U/g), phosphate
20 parts of enzyme (enzyme activity content >=10000U/g), is mixed, and control moisture is no more than 8%, is used as No. 2 material；
3) take containing cat's eye more than 5% and by 50 parts of calcareous montmorillonite, the gypsum 15 of 380 DEG C of high-temperature calcination expansions
Part, 15 parts of glauber salt, 20 parts of sodium bicarbonate, are mixed, and crush 40 mesh sieves, and control moisture is no more than 5%, is used as No. 3 material.
4) take after No. 1 material, No. 2 material, each 1 part of mixing of No. 3 material, according to 10:1 weight rate and yeast cell wall polysaccharide
(it contains beta glucan >=30%, and manna oligosacchride >=20%) is well mixed and produced, and control moisture is no more than 12%.
The feed addictive application method of in-pig prepared by the present invention is：In 90 days-phase of parturition of sow gestation
The standard for adding 2000 grams by sow perfect compound feed per ton is added in sow feed, is used after being well mixed.
Feed addictive of the present invention has advantages below：
1) comprehensive organism zymolysis technique of the present invention, using esterase degrade zearalenone and fumarubicin in feed,
The effect such as epoxidoreductase degraded T-2 and vomitoxin, victory peptase degraded ochratoxin, it is reasonably combined, reach thorough removing
The purpose of mycotoxin in enteron aisle.
2) glucose oxidase and catalase compatibility are taken, poison in interior free yl, hydrogen peroxide oxidation body is eliminated
The various toxicants such as element, make virose material in sow body become avirulent material, make H2O2Further it is transformed into nontoxic
H2O, is conducive to protection liver, kidney.Meanwhile, consume O during glucose oxidase catalysis glucose2, produce gluconic acid
And hydrogen peroxide, alimentary canal is more likely formed anaerobic environment, promote the propagation of anaerobism beneficial bacterium, play acidulant and probiotics
Effect, can improve alimentary canal acid digestion environment, and protection intestinal epithelial cell is complete, can suppress the increasing of harmful intestinal tract microorganism again
Grow, adjust the gut flora ecological balance.
3) increase and the change of molecular structure of the body surface area using the montmorillonite containing cat's eye in calcining expansion process
Change, strengthen endotoxin (such as lipopolysaccharides LPS) performance that toxin and internal harmful microorganism are produced in its adsorption feed, and do not inhale
Other nutritions in attached feed, thoroughly purify enterotoxin.
4) the yeast cell wall polysaccharide selected contains beta glucan >=30%, manna oligosacchride >=20%, with efficient immune
Mobilizing function, can improve the innate immune activity of in-pig, improve liver function, improve Related Immune Enzyme Activity, can delay
Solve all kinds of stress reactions of in-pig；There is stronger suction-operated to mycotoxin, may also suppress enteric pathogenic bacteria field planting；This
The mycotoxin that the active ingredient of invention feed addictive has been absorbed into blood after being absorbed with animal is combined, and toxin is transported into liver
Dirty removing toxic substances heel row removes external, therefore can remove the toxin absorbed, and de- mould dose of tradition then can not be by the toxin being absorbed by organisms
Remove external.
5) present invention takes the antibacterial peptide and Lactobacillus rhamnosus compatibility of Lactobacillus plantarum fermentation production, and fully regulation sow disappears
Change the microecological balance in road, the breeding of pathogen is prevented by adherence mechanism, competition exclution effect, suppresses pathogenic microorganism, builds
Normal enteron aisle dominant population is found and maintains, prevention sow disease occurs.Sow Instestinal motility is improved, prevention of sow constipation is eliminated, subtracts
Few toxin accumulation, reduces weak young stillborn foetus.Antibacterial peptide plays the few sow vertical infections of bactericidal effect , Minus.
6) for preferably heat-clearing, anti-inflammatory, detoxification, this product integrated use gypsum, glauber salt, sodium bicarbonate etc. are inorganic
Mineral matter, is compounded according to certain ratio, promotes the performance of above-mentioned compatibility raw material effect, reaches that collaboration conditioning in-pig is special
The purpose of physiological stage eubolism, promotes gestational period sow normally to search for food, and improves sow digestive function.
Embodiment
Embodiment 1：
1) Lactobacillus plantarum metabolite antibacterial peptide (potency >=10 are taken4U/g) 50 parts, Lactobacillus rhamnosus (content >=
107CFU/g) 50 parts, mix, control moisture is no more than 10%, be used as No. 1 material；
2) 20 parts of glucose oxidase (enzyme activity content >=1000U/g), the catalase of mould production of Aspergillus Niger are taken
20 parts of victory peptase (enzyme activity content >=1000U/g), the aspergillus niger of 20 parts of (enzyme activity content >=1000U/g), bacillus licheniformis production
20 parts of the epoxidoreductase (enzyme activity content >=1000U/g) of production, phosphate (the enzyme activity content >=10000U/ of Aspergillus Niger
G) 20 parts, mix, control moisture is no more than 8%, be used as No. 2 material；
3) take 50 parts of calcareous montmorillonite containing cat's eye more than 5% and by 380 DEG C of high-temperature calcinations expansion, gypsum (my god
Right calcium sulphate dihydrate, purity >=98.0%) 15 parts, 15 parts of glauber salt (sodium sulphate >=99.0%), sodium bicarbonate (sodium acid carbonate >=
99.0%) 20 parts, mix, crushed 40 mesh sieves, control moisture is no more than 5%, is used as No. 3 material.
4) take after No. 1 material, No. 2 material, each 1 part of mixing of No. 3 material, according to 10:1 weight rate and yeast cell wall polysaccharide
(it contains beta glucan >=30%, and manna oligosacchride >=20%) is well mixed and produced, and control moisture is no more than 12%.
The feed addictive application method of in-pig prepared by the present invention is：In 90 days-phase of parturition of sow gestation
The standard for adding 2000 grams by sow perfect compound feed per ton is added in sow feed, is used after being well mixed.
Illustrate a kind of feeding of the present invention-in-pig (pregnant 90 days-phase of parturition) below by way of specific test example
The beneficial effect of feed additives：
A kind of feed addictive of in-pig (pregnant 90 days-phase of parturition) is tested to in-pig production performance
Influence
40 3-5 parity of selection are in a good state of health, pregnant 88-90d large white sow, according to breeding age in days, parity,
Body condition, is randomly divided into control group and test group, each 20 repetitions of processing, each repeats 1 sow.Set using single factor experiment
Meter, basal diet is identical, and main nutrient composition is：Digestible energy 3000Mcal/kg, crude protein 13.00%, lysine 0.48%,
Methionine 0.12%, threonine 0.38%, tryptophan 0.10%, calcium 0.68%, available phosphorus 0.32%.In-pig is raised in limit
Bit field, is transferred to overhead obstetric table in antenatal 1 week.Control group fed basal diet, the diet of test group sow is added by basal diet per ton
Plus 2 kilograms of in-pig feed addictives of the present invention.Test pig environmental condition is consistent.Test period is October 20 in 2016
Day-November 22, place is Hunan original seed pig farm.Sow free water, and the routinely immune cleaning for carrying out environment of health care
Health.
Testing index is：Sow average daily gain, sows farrowing time interval, piglet birth weight, young rate living, strong son
Rate, stillborn foetus and mummy rate, lopsided and weak young rate, and record sow midwifery situation and postpartum disease a situation arises.It is pregnant female
Influence of the feed addictive of pig to sow average daily gain is shown in Table 1, and the influence to sow production performance index is shown in Table 2,
The influence of prevention and midwifery situation to sow postpartum disease is shown in Table 3.
Influence (kg/ day) of the feed addictive of the in-pig of table 1 to sow average daily gain
| Stage | Test group (20) | Control group (20) |
| Antenatal 30 days to antenatal 4 days | 6.12±0.41a | 5.87±0.18a |
| Antenatal 3 days-postpartum | 1.35±0.10a | 1.24±0.10a |
Note：The female different expression significant difference (P of data shoulder marking-up of going together<0.05), the not notable (P of identical expression difference>
0.05).Following table is same.
Influence of the feed addictive of the in-pig of table 2 to sow production performance index
| Index | Test group (20) | Control group (20) |
| Time interval of farrowing (min) | 18.03±4.23a | 31.11±5.49b |
| Average production piglet head number (head) living | 11.00±2.35a | 8.70±1.52b |
| Young average birth weight (kg) living | 1.47±0.28a | 1.42±0.35a |
| The strong young rate (%) of production | 97.92a | 90.91b |
| Stillborn foetus and mummy rate (%) | 0.00a | 2.28b |
| Lopsided and weak young rate (%) | 0.45a | 4.59b |
The feed addictive of the in-pig of table 3. is to the prevention of sow postpartum disease and the influence of midwifery situation
| Processing | Test group (20) | Control group (20) |
| Sow postpartum disease situation | 0 | 26 hours postpartum fevers, 3 metrias |
| The incidence of disease | 0% | 25.00% |
| Sow midwifery situation | 0 | 2 midwifery |
| Midwifery rate | 0% | 10.00% |
As a result show：Test group is compared with control group, and sow feed intake and the average birth weight of piglet have increased trend, but
Not notable (the P of difference>0.05).Test group sows farrowing interval time is significantly lower than control group, and number born alive, strong young number are all notable
Higher than control group, stillborn foetus and mummy rate, lopsided and weak young rate are substantially less than control group (P<0.05), test group sow need not
Midwifery, and without postpartum disease, hence it is evident that it is better than control group.
Therefore learn：The feed addictive of in-pig (pregnant 90 days-phase of parturition) of the present invention is given birth to in-pig
Production performance and premunition have certain effect.It is added in the pregnant 90 days-phase of parturition of in-pig by 2kg/t in feed, energy
Number born of sow and strong young number are effectively improved, significantly shortens sows farrowing time interval, significantly improves sow premunition, improves female
Swine reproduction performance.
Claims (3)
1. a kind of feed addictive of in-pig, it is characterised in that in parts by weight using No. 1 material, No. 2 material, No. 3
Expect after each 1 part of mixing according to 10:1 weight ratio is mixed with yeast cell wall polysaccharide and obtained；Wherein No. 1 material is by potency >=104U/g
50 parts of Lactobacillus plantarum metabolite antibacterial peptide, content >=107CFU/g 50 parts of compositions of Lactobacillus rhamnosus；No. 2 material are by enzyme
Content >=1000U/g living 20 parts of glucose oxidase, enzyme activity content >=1000U/g 20 parts of catalase, enzyme activity content
>=1000U/g 20 parts of peptase of victory, enzyme activity content >=1000U/g 20 parts of epoxidoreductase, enzyme activity content >=10000U/g
20 parts of phosphate composition；Calcareous montmorillonite 50 part of No. 3 material by cat's eye content >=5% and by 380 DEG C of high-temperature calcinations,
15 parts of gypsum, 15 parts of glauber salt, 20 parts of compositions of sodium bicarbonate.
2. a kind of preparation method of in-pig feed addictive, it is characterised in that comprise the following steps：
1) potency >=10 are taken4U/g 50 parts of Lactobacillus plantarum metabolite antibacterial peptide, content >=107The newborn bar of CFU/g rhamnose
50 parts of bacterium, mixes, and controls moisture≤10%, is used as No. 1 material；
2) enzyme activity content >=1000U/g 20 parts of 20 parts of glucose oxidase, catalase, 20 parts of peptase of victory, epoxidation is taken
20 parts of 20 parts of reductase and enzyme activity content >=10000U/g phosphate, is mixed, and is controlled moisture≤8%, is used as No. 2
Material；
3) take content containing cat's eye >=5% and by 50 parts of the calcareous montmorillonite of 380 DEG C of high-temperature calcinations expansion, 15 parts of gypsum,
15 parts of glauber salt, 20 parts of sodium bicarbonate, are mixed, and crush 40 mesh sieves, control moisture≤5%, are used as No. 3 material；
4) take after No. 1 material, No. 2 material, each 1 part of mixing of No. 3 material, according to 10:1 weight rate is mixed with yeast cell wall polysaccharide
It is even, moisture≤12% is controlled, is produced, containing beta glucan >=30% wherein in yeast cell wall polysaccharide, manna oligosacchride >=
20%.
3. a kind of application method of the gained in-pig feed addictive of claim 1 or 2, it is characterised in that be specially：
The standard that 90 days-phase of parturition of sow gestation adds 2000 grams of feed addictives by sow perfect compound feed per ton is added to mother
In pig feed, and it is well mixed after use.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2017104433015 | 2017-06-13 | ||
| CN201710443301 | 2017-06-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107259141A true CN107259141A (en) | 2017-10-20 |
| CN107259141B CN107259141B (en) | 2021-06-22 |
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| CN201710511498.1A Active CN107259141B (en) | 2017-06-13 | 2017-06-28 | Feed additive for pregnant sows and preparation and use methods thereof |
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Cited By (7)
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| CN108850604A (en) * | 2018-07-17 | 2018-11-23 | 江苏奥迈生物科技有限公司 | A kind of pregnant sow compound premixed feed and preparation method thereof |
| CN110506851A (en) * | 2019-08-13 | 2019-11-29 | 安徽快康生物科技有限公司 | A kind of feed addictive and feed for mycotoxin in livestock and poultry body of degrading |
| CN111802524A (en) * | 2020-07-31 | 2020-10-23 | 山东利邦牧业股份有限公司 | Antioxidant free radical detoxifying promoting additive for sows |
| CN112674222A (en) * | 2020-12-24 | 2021-04-20 | 长沙希邦生物科技有限公司 | Pregnant sow feed for achieving high yield of thirteen litters of sows |
| CN113383864A (en) * | 2021-05-25 | 2021-09-14 | 长沙道勤生物科技有限公司 | Antibiotic-free feed for helping sow delivery and relieving postpartum syndrome |
| CN114072008A (en) * | 2019-05-31 | 2022-02-18 | 纽崔桂斯特有限责任公司 | Therapeutic clay compositions and methods of use |
| CN117837692A (en) * | 2024-02-23 | 2024-04-09 | 广东新富民农牧有限责任公司 | Special bioactive feed for pregnant sows and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108850604A (en) * | 2018-07-17 | 2018-11-23 | 江苏奥迈生物科技有限公司 | A kind of pregnant sow compound premixed feed and preparation method thereof |
| CN114072008A (en) * | 2019-05-31 | 2022-02-18 | 纽崔桂斯特有限责任公司 | Therapeutic clay compositions and methods of use |
| CN114072008B (en) * | 2019-05-31 | 2025-03-14 | 纽崔桂斯特有限责任公司 | Therapeutic clay compositions and methods of use |
| CN110506851A (en) * | 2019-08-13 | 2019-11-29 | 安徽快康生物科技有限公司 | A kind of feed addictive and feed for mycotoxin in livestock and poultry body of degrading |
| CN111802524A (en) * | 2020-07-31 | 2020-10-23 | 山东利邦牧业股份有限公司 | Antioxidant free radical detoxifying promoting additive for sows |
| CN112674222A (en) * | 2020-12-24 | 2021-04-20 | 长沙希邦生物科技有限公司 | Pregnant sow feed for achieving high yield of thirteen litters of sows |
| CN113383864A (en) * | 2021-05-25 | 2021-09-14 | 长沙道勤生物科技有限公司 | Antibiotic-free feed for helping sow delivery and relieving postpartum syndrome |
| CN117837692A (en) * | 2024-02-23 | 2024-04-09 | 广东新富民农牧有限责任公司 | Special bioactive feed for pregnant sows and preparation method thereof |
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