CN107198232A - A kind of health products promoted longevity - Google Patents
A kind of health products promoted longevity Download PDFInfo
- Publication number
- CN107198232A CN107198232A CN201710472485.8A CN201710472485A CN107198232A CN 107198232 A CN107198232 A CN 107198232A CN 201710472485 A CN201710472485 A CN 201710472485A CN 107198232 A CN107198232 A CN 107198232A
- Authority
- CN
- China
- Prior art keywords
- pterostilbene
- resveratrol
- niacinamide
- active ingredient
- promoted longevity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000036541 health Effects 0.000 title claims abstract description 32
- VLEUZFDZJKSGMX-ONEGZZNKSA-N pterostilbene Chemical compound COC1=CC(OC)=CC(\C=C\C=2C=CC(O)=CC=2)=C1 VLEUZFDZJKSGMX-ONEGZZNKSA-N 0.000 claims abstract description 51
- VLEUZFDZJKSGMX-UHFFFAOYSA-N pterostilbene Natural products COC1=CC(OC)=CC(C=CC=2C=CC(O)=CC=2)=C1 VLEUZFDZJKSGMX-UHFFFAOYSA-N 0.000 claims abstract description 51
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims abstract description 47
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims abstract description 47
- 235000021283 resveratrol Nutrition 0.000 claims abstract description 47
- 229940016667 resveratrol Drugs 0.000 claims abstract description 47
- 235000005152 nicotinamide Nutrition 0.000 claims abstract description 44
- 239000011570 nicotinamide Substances 0.000 claims abstract description 44
- 229960003966 nicotinamide Drugs 0.000 claims abstract description 44
- 108020004707 nucleic acids Proteins 0.000 claims abstract description 22
- 102000039446 nucleic acids Human genes 0.000 claims abstract description 22
- 239000004480 active ingredient Substances 0.000 claims abstract description 17
- 239000002775 capsule Substances 0.000 claims abstract description 15
- -1 niacinamide nucleic acid Chemical class 0.000 claims abstract description 13
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 235000013361 beverage Nutrition 0.000 claims abstract description 7
- 239000003937 drug carrier Substances 0.000 claims abstract description 6
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 3
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims description 26
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims description 26
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims description 26
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 16
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 16
- 229920002678 cellulose Polymers 0.000 claims description 15
- 239000001913 cellulose Substances 0.000 claims description 15
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 14
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 14
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 14
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims description 11
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims description 11
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 11
- 235000012907 honey Nutrition 0.000 claims description 8
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 8
- 239000000377 silicon dioxide Substances 0.000 claims description 8
- 235000019359 magnesium stearate Nutrition 0.000 claims description 4
- 240000006122 Chenopodium album Species 0.000 claims description 3
- 235000009344 Chenopodium album Nutrition 0.000 claims description 3
- 235000014676 Phragmites communis Nutrition 0.000 claims description 3
- 241000489523 Veratrum Species 0.000 claims description 2
- HSHXDCVZWHOWCS-UHFFFAOYSA-N N'-hexadecylthiophene-2-carbohydrazide Chemical compound CCCCCCCCCCCCCCCCNNC(=O)c1cccs1 HSHXDCVZWHOWCS-UHFFFAOYSA-N 0.000 claims 2
- 235000019504 cigarettes Nutrition 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 16
- 239000000203 mixture Substances 0.000 abstract description 14
- 108090000623 proteins and genes Proteins 0.000 abstract description 11
- 239000004472 Lysine Substances 0.000 abstract description 7
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract description 6
- 230000009471 action Effects 0.000 abstract description 6
- 239000000126 substance Substances 0.000 abstract description 3
- XTEGARKTQYYJKE-UHFFFAOYSA-N chloric acid Chemical compound OCl(=O)=O XTEGARKTQYYJKE-UHFFFAOYSA-N 0.000 abstract description 2
- 229940005991 chloric acid Drugs 0.000 abstract description 2
- 238000009472 formulation Methods 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000004615 ingredient Substances 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 238000001035 drying Methods 0.000 description 8
- VIKNJXKGJWUCNN-XGXHKTLJSA-N norethisterone Chemical compound O=C1CC[C@@H]2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 VIKNJXKGJWUCNN-XGXHKTLJSA-N 0.000 description 8
- 239000000243 solution Substances 0.000 description 7
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 6
- 238000011160 research Methods 0.000 description 5
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 4
- 229910052749 magnesium Inorganic materials 0.000 description 4
- 239000011777 magnesium Substances 0.000 description 4
- BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 description 3
- 230000003712 anti-aging effect Effects 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 229920003091 Methocel™ Polymers 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 230000006196 deacetylation Effects 0.000 description 1
- 238000003381 deacetylation reaction Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 229940096978 oral tablet Drugs 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of health products promoted longevity, including core active ingredient niacinamide nucleic acid, pterostilbene and resveratrol and pharmaceutically acceptable carrier.The mass ratio of the niacinamide nucleic acid, pterostilbene and resveratrol is（5‑10）∶（1‑3）∶（5‑10）.The core active ingredient and pharmaceutically acceptable carrier are prepared into the formulations such as piece agent, capsule, oral liquid or wine, beverage.The present invention has been successfully found the niacinamide nucleic acid for making longevity gene reach optimum level and make bad chloric acid deacetylase activity reach optimum level; pterostilbene and the optimal proportion and optimal dose of resveratrol three; the creative chemical composition by three different action principles or different site of action integrates according to optimal ratio; the synergy of three is played to greatest extent; the expression of longevity gene and the activity of lysine deacetylase is reached optimum state, thus reach the maximum effect promoted longevity.
Description
Technical field
The present invention relates to a kind of health products, and in particular to the health products with effect of promoting longevity.
Background technology
With the raising of standard of living, the health perception of people is more and more stronger, health knowledge is increasingly paid close attention to, to health
Cognitive more science, thus to health care, anti-aging proposes higher requirement.People are not it may be desirable to long-lived, while also wishing
Hope can be more healthy life.The achievement in research of Massachusetts Institute Technology Leonard doctors Guarente, has opened the mankind and has been good for
Kang Changshou secret -- longevity gene.Longevity gene is activated, the life more than 30% of experimental animal, Er Qieneng can not only be made
Make experimental animal more healthy.Further investigation revealed that in addition to starvation, some materials are some including what is separated from plant
Chemical substance equally has the work(of the expression of activation longevity gene and/or increase longevity gene product-lysine deacetylase activity
Effect.Niacinamide ribose, is another form that vitamin nicotinic acid is present, NAD+ is convertible into vivo.NAD+ is de- for lysine
The coenzyme of acetyl group enzyme.Internal NAD+ contents are higher within the specific limits, and the activity of lysine deacetylase is higher.Pterostilbene
It is present in resveratrol in many plants, is natural, with very strong anti-oxidant, anti-aging, anticancer and raising
The effect of immunologic function.Substantial amounts of research has shown that Pterostilbene and resveratrol can directly activate the expression of longevity gene in vivo,
Thus with anti-aging and the function of promoting longevity.Further research has shown that both pterostilbene and resveratrol share, and it resists
Aging and the effect promoted longevity are remarkably reinforced, thus with synergy.Pterostilbene and resveratrol activate longevity in vivo
The expression of gene is related to its concentration within the specific limits, and the activity of same lysine deacetylase is within the specific limits
It is related to the concentration of internal niacinamide ribose.
The content of the invention
It is an object of the invention to provide one kind, by by the chemistry of three kinds of different action principles and different site of action into
Divide and integrate, the synergy of three is played to greatest extent, makes the expression and lysine deacetylation of longevity gene
The activity of enzyme reaches optimum state, thus reaches the maximum effect promoted longevity.
The technical solution adopted by the present invention is as follows：A kind of health products promoted longevity, including core active ingredient niacinamide
Nucleic acid, pterostilbene and resveratrol and pharmaceutically acceptable carrier.
Further, the mass ratio of the niacinamide nucleic acid, pterostilbene and resveratrol is（5-10）∶（1-3）∶（5-
10）.
Further, the core active ingredient and pharmaceutically acceptable carrier are prepared into piece agent, capsule, oral liquid
Or wine, beverage.
Further, tablet is made using the core active ingredient and auxiliary material of following weight percentage：Niacinamide ribose
10-25%, pterostilbene 1.25-7.5%, resveratrol 10-25%, cellulose 37.5-67.5%, hydroxypropyl methyl cellulose 2.5-
7.5%, magnesium stearate 1-2.5%, silica 0.25-1%.
Further, capsule is made using the core active ingredient and auxiliary material of following weight percentage：Niacinamide ribose 10-
25%, pterostilbene 1.25-7.5%, resveratrol 10-25%, cellulose 40-71%, hydroxypropyl methyl cellulose 2.5-7.5%.
Further, oral liquid is made using the core active ingredient and auxiliary material of following weight percentage：Niacinamide ribose
2.0-5.0%, pterostilbene 0.25-1.5%, resveratrol 2.0-5.0%, propane diols 2.0-5.0%, honey 5.0-10%, water 74-
88%。
Further, health liquor is made using the core active ingredient and auxiliary material of following weight percentage：Niacinamide ribose
0.2-0.5%, pterostilbene 0.025-0.15%, resveratrol 0.2-0.5%, ethanol 7.5-15%, water 85-92%.
Further, health drink is made using the core active ingredient and auxiliary material of following weight percentage：Niacinamide core
Sugared 0.04-0.1%, pterostilbene 0.005-0.03%, resveratrol 0.04-0.1%, propane diols 0.04-0.1%, arabinose
0.5-1.5%, citric acid 1-2.5%, water 96-98.2%.
The present invention, with putting into practice and combining existing substantial amounts of advanced achievement in research both at home and abroad, is successfully looked for by years of researches
To the niacinamide core for making longevity gene reach optimum level and make bad chloric acid deacetylase activity reach optimum level
The optimal proportion and optimal dose of acid, pterostilbene and resveratrol three, it is creative by three different action principles or difference
The chemical composition of site of action integrates according to optimal ratio, and the synergy of three is played to greatest extent, makes longevity
The expression of gene and the activity of lysine deacetylase reach optimum state, thus reach the maximum work promoted longevity
Effect.
Embodiment
The present invention is described in further detail with reference to embodiment, but present disclosure is not limited to be lifted
Embodiment.
Embodiment 1
Niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol are added into cellulose, hydroxypropyl methyl cellulose, tristearin
Sour magnesium, silica are fully mixed thoroughly in proportion, plus appropriate distilled water continues to stir, then tabletting, a piece of by one gram, under temperature control
Drying, drying temperature is controlled in 40-60 degree, drying time 1-2 hours.A piece of composition includes：100 milligrams of niacinamide nucleic acid,
12.5 milligrams of pterostilbene, 100 milligrams of resveratrol, 677.5 milligrams of cellulose, 75 milligrams of hydroxypropyl methyl cellulose, firmly
25 milligrams of fatty acid magnesium, 10 milligrams of silica.
Embodiment 2
Niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol are added into cellulose, hydroxypropyl methyl cellulose, tristearin
Sour magnesium, silica are fully mixed thoroughly in proportion, plus appropriate distilled water continues to stir, then tabletting, a piece of by one gram, under temperature control
Drying, drying temperature is controlled in 40-60 degree, drying time 1-2 hours.A piece of composition includes：150 milligrams of niacinamide nucleic acid,
35 milligrams of pterostilbene, 150 milligrams of resveratrol, 595 milligrams of cellulose, propyl methocel 50,15 milligrams of magnesium stearate,
5 milligrams of silica.
Embodiment 3
Niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol are added into cellulose, hydroxypropyl methyl cellulose, tristearin
Sour magnesium, silica are fully mixed thoroughly by predetermined ratio, plus appropriate distilled water continues to stir, then tabletting, a piece of by one gram, control
Temperature is lower to be dried, and drying temperature is controlled in 40-60 degree, drying time 1-2 hours.A piece of composition includes：The milli of niacinamide nucleic acid 250
Gram, 75 milligrams of pterostilbene, 250 milligrams of resveratrol, 387.5 grams of cellulose, propyl methocel 25, the milli of magnesium stearate 10
Gram, 2.5 milligrams of silica.
Embodiment 4
Niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol are added into cellulose, hydroxypropyl methyl cellulose in proportion
Fully mix thoroughly, canned capsule, every capsule contains 1 gram of mixture.Every capsule mix ingredients includes：The milli of niacinamide nucleic acid 100
Gram, 12.5 milligrams of pterostilbene, 100 milligrams of resveratrol, 712.5 milligrams of cellulose, the milli of hydroxypropyl methyl cellulose 75
Gram.
Embodiment 5
Niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol are added into cellulose, hydroxypropyl methyl cellulose in proportion
Fully mix thoroughly, canned capsule, every capsule contains 1 gram of mixture.Every capsule mix ingredients includes：The milli of niacinamide nucleic acid 150
Gram, 35 milligrams of pterostilbene, 150 milligrams of resveratrol, 615 milligrams of cellulose, 50 milligrams of hydroxypropyl methyl cellulose.
Embodiment 6
By niacinamide ribose, pterostilbene, three kinds of effective ingredients of resveratrol plus cellulose, hydroxypropyl methyl cellulose press than
Example is fully mixed thoroughly, canned capsule, and every capsule contains 1 gram of mixture.Every capsule mix ingredients includes：Niacinamide nucleic acid 250
Milligram, 75 milligrams of pterostilbene, 250 milligrams of resveratrol, 400 milligrams of cellulose, 25 milligrams of hydroxypropyl methyl cellulose.
Embodiment 7
Niacinamide ribose, pterostilbene, resveratrol are dissolved in propane diols by predetermined ratio and concentration, then added by predetermined ratio
Honey and water are prepared into oral liquid.Every 100 milligrams of the 5 milliliters of niacinamide-containing nucleic acid of oral liquid of preparation, 12.5 milligrams of pterostilbene,
100 milligrams of resveratrol, 0.125 milliliter of propane diols, 0.3 milliliter of honey, 4.4 milliliters of water.
Embodiment 8
Niacinamide ribose, pterostilbene, resveratrol are dissolved in propane diols by predetermined ratio and concentration, then added by predetermined ratio
Honey and water are prepared into oral liquid.Every 150 milligrams of the 5 milliliters of niacinamide-containing nucleic acid of oral liquid of preparation, 35 milligrams of pterostilbene, white lamb's-quarters
150 milligrams of reed alcohol, 0.2 milliliter of propane diols, 0.4 milliliter of honey, 4.1 milliliters of water.
Embodiment 9
Niacinamide ribose, pterostilbene, resveratrol are dissolved in propane diols by predetermined ratio and concentration, then added by predetermined ratio
Honey and water are prepared into oral liquid.Every 250 milligrams of the 5 milliliters of niacinamide-containing nucleic acid of oral liquid of preparation, 75 milligrams of pterostilbene, white lamb's-quarters
250 milligrams of reed alcohol, 0.25 milliliter of propane diols, 0.5 milliliter of honey, 3.7 milliliters of water.
Embodiment 10
Niacinamide ribose, pterostilbene and resveratrol are dissolved in 70% ethanol by predetermined ratio and concentration, dilution is then added water
Health liquor is made.Every 100 milligrams of the 50 milliliters of niacinamide-containing nucleic acid of health liquor being made, purple 12.5 milligrams of purlin stilbene, resveratrol 100
Milligram, 3.8 milliliters of ethanol, 46.0 milliliters of water.
Embodiment 11
Niacinamide ribose, pterostilbene and resveratrol are dissolved in 70% ethanol by predetermined ratio and concentration, dilution is then added water
Health liquor is made.Every 150 milligrams of the 50 milliliters of niacinamide-containing nucleic acid of health liquor being made, 35 milligrams of pterostilbene, the milli of resveratrol 150
Gram, 5 milliliters of ethanol, 45 milliliters of water.
Embodiment 12
Niacinamide ribose, pterostilbene and resveratrol are dissolved in 70% ethanol by predetermined ratio and concentration, dilution is then added water
Health liquor is made.Every 250 milligrams of the 50 milliliters of niacinamide-containing nucleic acid of health liquor being made, 75 milligrams of pterostilbene, the milli of resveratrol 250
Gram, 7.0 milliliters of ethanol, 42.5 milliliters of water.
Embodiment 13
Niacinamide ribose, pterostilbene and resveratrol are dissolved in propane diols by predetermined ratio and concentration；By arabinose by predetermined
Concentration is dissolved in water；Propylene glycol solution and arabinose solution are mixed by predetermined ratio, then citric acid is added by predetermined concentration,
Finally it is prepared into health drink.Every 100 milligrams of 250 milliliters of beverage niacinamide-containings nucleic acid, 12.5 milligrams of pterostilbene, resveratrol
100 milligrams, 0.15 milliliter of propane diols, 1.5 grams of arabinose, 2.75 milliliters of citric acid, 245.5 milliliters of water.
Embodiment 14
Niacinamide ribose, pterostilbene and resveratrol are dissolved in propane diols by predetermined ratio and concentration；By arabinose by predetermined
Concentration is dissolved in water；Propylene glycol solution and arabinose solution are mixed by predetermined ratio, then citric acid is added by predetermined concentration,
Finally it is prepared into health drink.Every 150 milligrams of 250 milliliters of beverage niacinamide-containings nucleic acid, 35 milligrams of pterostilbene, the white milli of black false hellebore 150
Gram, 0.2 milliliter of propane diols, 2.5 grams of arabinose, 4.0 milliliters of citric acid, 243 milliliters of water.
Embodiment 15
Niacinamide ribose, pterostilbene and resveratrol are dissolved in propane diols by predetermined ratio and concentration；By arabinose by predetermined
Concentration is dissolved in water；Propylene glycol solution and arabinose solution are mixed by predetermined ratio, then citric acid is added by predetermined concentration,
Finally it is prepared into health drink.Every 250 milligrams of 250 milliliters of beverage niacinamide-containings nucleic acid, 75 milligrams of pterostilbene, resveratrol 250
Milligram, 0.25 milliliter of propane diols, 3.0 grams of arabinose, 6.25 milliliters of citric acid, 241 milliliters of water.
Being prepared into oral tablet, capsule, oral liquid, wine, beverage respectively above can be by the interaction of raw material, tool
There are strengthen immunity, anticancer, kidney tonifying, physical fitness, the effect promoted longevity.It is to grow up for more than 18 years old that this health products, which is adapted to crowd,
People.
Claims (8)
1. a kind of health products promoted longevity, it is characterised in that：Including core active ingredient niacinamide nucleic acid, pterostilbene and white lamb's-quarters
Reed alcohol and pharmaceutically acceptable carrier.
2. a kind of health caring product prescription promoted longevity as claimed in claim 1, it is characterised in that：The core active ingredient cigarette
The mass ratio of acid amides nucleic acid, pterostilbene and resveratrol is（5-10）∶（1-3）∶（5-10）.
3. a kind of health products promoted longevity as claimed in claim 1 or 2, it is characterised in that：By the core active ingredient
Piece agent, capsule, oral liquid or wine, beverage are prepared with pharmaceutically acceptable carrier.
4. a kind of health products promoted longevity as claimed in claim 3, it is characterised in that using following weight percentage
Tablet is made with auxiliary material in core active ingredient：Niacinamide ribose 10-25%, pterostilbene 1.25-7.5%, resveratrol 10-25%,
Cellulose 37.5-67.5%, hydroxypropyl methyl cellulose 2.5-7.5%, magnesium stearate 1-2.5%, silica 0.25-1%.
5. a kind of health products promoted longevity as claimed in claim 3, it is characterised in that using the core of following weight percentage
Capsule is made with auxiliary material in heart active ingredient：Niacinamide ribose 10-25%, pterostilbene 1.25-7.5%, resveratrol 10-25%, fiber
Plain 40-71%, hydroxypropyl methyl cellulose 2.5-7.5%.
6. a kind of health products promoted longevity as claimed in claim 3, it is characterised in that using following weight percentage
Oral liquid is made with auxiliary material in core active ingredient：Niacinamide ribose 2.0-5.0%, pterostilbene 0.25-1.5%, resveratrol 2.0-
5.0%, propane diols 2.0-5.0%, honey 5.0-10%, water 74-88%.
7. a kind of health products promoted longevity as claimed in claim 3, it is characterised in that using the core of following weight percentage
Health liquor is made with auxiliary material in heart active ingredient：Niacinamide ribose 0.2-0.5%, pterostilbene 0.025-0.15%, resveratrol 0.2-
0.5%, ethanol 7.5-15%, water 85-92%.
8. a kind of health products promoted longevity as claimed in claim 3, it is characterised in that using following weight percentage
Health drink is made with auxiliary material in core active ingredient：Niacinamide ribose 0.04-0.1%, pterostilbene 0.005-0.03%, white black false hellebore
Alcohol 0.04-0.1%, propane diols 0.04-0.1%, arabinose 0.5-1.5%, citric acid 1-2.5%, water 96-98.2%.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107692230A (en) * | 2017-10-10 | 2018-02-16 | 仲恺农业工程学院 | Health care product containing resveratrol and luteolin and preparation method and application thereof |
| CN111601514A (en) * | 2018-01-15 | 2020-08-28 | 斯尔特500公司 | Nutraceutical composition for activation of sirtuin with anti-aging/anti-aging effects |
| CN115553352A (en) * | 2022-08-31 | 2023-01-03 | 上海玖咖科技有限公司 | Health-care beverage and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017062311A1 (en) * | 2015-10-07 | 2017-04-13 | Huizenga Joel | Resetting biological pathways for defending against and repairing deterioration from human aging |
-
2017
- 2017-06-21 CN CN201710472485.8A patent/CN107198232A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017062311A1 (en) * | 2015-10-07 | 2017-04-13 | Huizenga Joel | Resetting biological pathways for defending against and repairing deterioration from human aging |
Non-Patent Citations (2)
| Title |
|---|
| SHIN-ICHIRO IMAI: ""A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis"", 《PHARMACOL RES.》 * |
| 苏式兵等: "《生命科学前沿技术与中医药研究》", 30 September 2013, 上海浦江教育出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107692230A (en) * | 2017-10-10 | 2018-02-16 | 仲恺农业工程学院 | Health care product containing resveratrol and luteolin and preparation method and application thereof |
| CN111601514A (en) * | 2018-01-15 | 2020-08-28 | 斯尔特500公司 | Nutraceutical composition for activation of sirtuin with anti-aging/anti-aging effects |
| CN115553352A (en) * | 2022-08-31 | 2023-01-03 | 上海玖咖科技有限公司 | Health-care beverage and preparation method thereof |
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Application publication date: 20170926 |