CN106962363B - 一种含叶菌唑的协同减量杀菌组合物 - Google Patents
一种含叶菌唑的协同减量杀菌组合物 Download PDFInfo
- Publication number
- CN106962363B CN106962363B CN201710387750.2A CN201710387750A CN106962363B CN 106962363 B CN106962363 B CN 106962363B CN 201710387750 A CN201710387750 A CN 201710387750A CN 106962363 B CN106962363 B CN 106962363B
- Authority
- CN
- China
- Prior art keywords
- metconazole
- fluxapyroxad
- cyano
- amino
- wheat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000005868 Metconazole Substances 0.000 title claims abstract description 35
- XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 11
- 230000002195 synergetic effect Effects 0.000 title abstract description 12
- 239000013585 weight reducing agent Substances 0.000 title description 2
- 241000209140 Triticum Species 0.000 claims abstract description 28
- 235000021307 Triticum Nutrition 0.000 claims abstract description 28
- 241000221785 Erysiphales Species 0.000 claims abstract description 12
- 239000005788 Fluxapyroxad Substances 0.000 claims abstract description 12
- 201000010099 disease Diseases 0.000 claims abstract description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 12
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 11
- 235000009566 rice Nutrition 0.000 claims abstract description 11
- SXSGXWCSHSVPGB-UHFFFAOYSA-N fluxapyroxad Chemical compound FC(F)C1=NN(C)C=C1C(=O)NC1=CC=CC=C1C1=CC(F)=C(F)C(F)=C1 SXSGXWCSHSVPGB-UHFFFAOYSA-N 0.000 claims abstract description 9
- 241000223218 Fusarium Species 0.000 claims abstract description 4
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims abstract description 4
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 claims abstract description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims abstract 8
- 241000209094 Oryza Species 0.000 claims abstract 4
- 241000190142 Neofusicoccum ribis Species 0.000 claims abstract 2
- 235000013399 edible fruits Nutrition 0.000 claims abstract 2
- 239000000575 pesticide Substances 0.000 claims description 15
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 239000000417 fungicide Substances 0.000 claims description 12
- 230000000855 fungicidal effect Effects 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 5
- 239000000839 emulsion Substances 0.000 claims description 4
- 239000004563 wettable powder Substances 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000000375 suspending agent Substances 0.000 claims description 3
- 239000004530 micro-emulsion Substances 0.000 claims description 2
- 239000007900 aqueous suspension Substances 0.000 claims 1
- 239000000645 desinfectant Substances 0.000 claims 1
- 230000000361 pesticidal effect Effects 0.000 claims 1
- 239000004548 suspo-emulsion Substances 0.000 claims 1
- 206010039509 Scab Diseases 0.000 abstract description 10
- 208000031888 Mycoses Diseases 0.000 abstract description 4
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 45
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 23
- 229910052731 fluorine Inorganic materials 0.000 description 23
- 239000011737 fluorine Substances 0.000 description 23
- 229920000056 polyoxyethylene ether Polymers 0.000 description 13
- 229940051841 polyoxyethylene ether Drugs 0.000 description 13
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 12
- 239000003814 drug Substances 0.000 description 12
- -1 pyrazole amide Chemical class 0.000 description 12
- 238000012360 testing method Methods 0.000 description 10
- 229940079593 drug Drugs 0.000 description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 8
- 240000007594 Oryza sativa Species 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 238000011161 development Methods 0.000 description 6
- 230000018109 developmental process Effects 0.000 description 6
- 150000002191 fatty alcohols Chemical class 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000002265 prevention Effects 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 244000052616 bacterial pathogen Species 0.000 description 4
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 4
- 238000010998 test method Methods 0.000 description 4
- 150000003852 triazoles Chemical class 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 229920005551 calcium lignosulfonate Polymers 0.000 description 3
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000002270 dispersing agent Substances 0.000 description 3
- 239000004495 emulsifiable concentrate Substances 0.000 description 3
- 239000003995 emulsifying agent Substances 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 3
- 238000001228 spectrum Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000004546 suspension concentrate Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- 239000000080 wetting agent Substances 0.000 description 3
- WURBVZBTWMNKQT-UHFFFAOYSA-N 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one Chemical compound C1=NC=NN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 WURBVZBTWMNKQT-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 241000607479 Yersinia pestis Species 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000006229 carbon black Substances 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 239000013530 defoamer Substances 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 229930182490 saponin Natural products 0.000 description 2
- 150000007949 saponins Chemical class 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- ZMESHQOXZMOOQQ-UHFFFAOYSA-N 1-(naphthalen-1-ylmethyl)naphthalene Chemical compound C1=CC=C2C(CC=3C4=CC=CC=C4C=CC=3)=CC=CC2=C1 ZMESHQOXZMOOQQ-UHFFFAOYSA-N 0.000 description 1
- XEGMDUOAESTQCC-UHFFFAOYSA-N 1-(naphthalen-1-ylmethyl)naphthalene;sodium Chemical compound [Na].C1=CC=C2C(CC=3C4=CC=CC=C4C=CC=3)=CC=CC2=C1 XEGMDUOAESTQCC-UHFFFAOYSA-N 0.000 description 1
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 1
- TURPNXCLLLFJAP-UHFFFAOYSA-N 2-[2-(2-hydroxyethoxy)ethoxy]ethyl hydrogen sulfate Chemical compound OCCOCCOCCOS(O)(=O)=O TURPNXCLLLFJAP-UHFFFAOYSA-N 0.000 description 1
- DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 description 1
- KXGFMDJXCMQABM-UHFFFAOYSA-N 2-methoxy-6-methylphenol Chemical compound [CH]OC1=CC=CC([CH])=C1O KXGFMDJXCMQABM-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- BVZKSCINZZZBCW-UHFFFAOYSA-M C1(=CC=CC=C1)S(=O)(=O)[O-].C(CCCCCCCCCCC)[Ca+] Chemical compound C1(=CC=CC=C1)S(=O)(=O)[O-].C(CCCCCCCCCCC)[Ca+] BVZKSCINZZZBCW-UHFFFAOYSA-M 0.000 description 1
- TUGYIMVHPWPMBE-UHFFFAOYSA-N C=CC1=C(C=CC2=CC=CC=C12)C.[Na] Chemical compound C=CC1=C(C=CC2=CC=CC=C12)C.[Na] TUGYIMVHPWPMBE-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 229940124186 Dehydrogenase inhibitor Drugs 0.000 description 1
- 239000005760 Difenoconazole Substances 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- 241000223195 Fusarium graminearum Species 0.000 description 1
- 241000223221 Fusarium oxysporum Species 0.000 description 1
- 241000233732 Fusarium verticillioides Species 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 240000008790 Musa x paradisiaca Species 0.000 description 1
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 231100000674 Phytotoxicity Toxicity 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 239000006004 Quartz sand Substances 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 description 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 description 1
- 241000219094 Vitaceae Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000001089 [(2R)-oxolan-2-yl]methanol Substances 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 239000002518 antifoaming agent Substances 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 235000021015 bananas Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 1
- RNWGYDIGXJHCHP-UHFFFAOYSA-L calcium;dodecane-1-sulfonate Chemical compound [Ca+2].CCCCCCCCCCCCS([O-])(=O)=O.CCCCCCCCCCCCS([O-])(=O)=O RNWGYDIGXJHCHP-UHFFFAOYSA-L 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- FHADKOBMYTWGLE-UHFFFAOYSA-N cyclohexanol 1,4-dioxane Chemical compound O1CCOCC1.C1(CCCCC1)O FHADKOBMYTWGLE-UHFFFAOYSA-N 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- BQYJATMQXGBDHF-UHFFFAOYSA-N difenoconazole Chemical compound O1C(C)COC1(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)Cl)CN1N=CN=C1 BQYJATMQXGBDHF-UHFFFAOYSA-N 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 235000021186 dishes Nutrition 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- UWLPCYBIJSLGQO-UHFFFAOYSA-N dodecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCC(O)=O UWLPCYBIJSLGQO-UHFFFAOYSA-N 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- YKRQBWKLHCEKQH-UHFFFAOYSA-N ethyl 3-amino-2-cyano-3-phenylprop-2-enoate Chemical compound CCOC(=O)C(C#N)=C(N)C1=CC=CC=C1 YKRQBWKLHCEKQH-UHFFFAOYSA-N 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 235000021021 grapes Nutrition 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 230000028644 hyphal growth Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 230000009916 joint effect Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- LCRMGUFGEDUSOG-UHFFFAOYSA-N naphthalen-1-ylsulfonyloxymethyl naphthalene-1-sulfonate;sodium Chemical compound [Na].C1=CC=C2C(S(=O)(OCOS(=O)(=O)C=3C4=CC=CC=C4C=CC=3)=O)=CC=CC2=C1 LCRMGUFGEDUSOG-UHFFFAOYSA-N 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000012053 oil suspension Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- QRJJEGAJXVEBNE-MOHJPFBDSA-N oxiconazole Chemical compound ClC1=CC(Cl)=CC=C1CO\N=C(C=1C(=CC(Cl)=CC=1)Cl)\CN1C=NC=C1 QRJJEGAJXVEBNE-MOHJPFBDSA-N 0.000 description 1
- 229960003483 oxiconazole Drugs 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 229920005552 sodium lignosulfonate Polymers 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 230000004763 spore germination Effects 0.000 description 1
- 230000028070 sporulation Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- BSYVTEYKTMYBMK-UHFFFAOYSA-N tetrahydrofurfuryl alcohol Chemical compound OCC1CCCO1 BSYVTEYKTMYBMK-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明涉及一种含叶菌唑的协同减量杀菌组合物，其特征在于，所述的杀菌组合物以氰烯菌酯、叶菌唑和氟唑菌酰胺为有效成分，氰烯菌酯、叶菌唑和氟唑菌酰胺的重量比为1‑80:1‑80:1‑80，用于防治小麦赤霉病，小麦白粉病、小麦锈病、瓜类枯萎病、苹果炭疽病、苹果腐烂病，小麦纹枯病、水稻稻瘟病、水稻恶苗病等真菌性病害，增效效果明显。
Description
技术领域：
本发明属于农业杀菌剂领域，具体的涉及一种含叶菌唑的协同减量杀菌组合物及其应用。
背景技术：
氰烯菌酯，试验号：JS399-19，化学名称为：2-氰基-3-氨基-3-苯基丙烯酸乙酯。由江苏省农药研究所合成，是具有我国自主的知识产权的新型杀菌剂。该药剂耐雨水冲刷，具有良好的内吸穿透性能及优异的保护和治疗作用。氰烯菌酯对镰刀菌属的禾谷镰刀菌、串珠镰刀菌、尖孢镰刀菌等均有很高的生物活性，适用于小麦赤霉病、水稻恶苗病和西瓜枯萎病等作物病害的有效防治。
室内研究表明，赤霉病菌在此类药剂高的药剂选择压下极易产生抗药性，存在一定的抗药性风险。因此在目前抗病品种缺乏的情况下，为了延缓或克服病原菌抗药性的形成和发展，避免连续单一的使用氰烯菌酯，应与其他类型的杀菌剂轮换或混合使用。
叶菌唑(Metconazole)，又叫羟菌唑，化学名称：5-(4-氯苯基)-2,2-二甲基-1-(1,2,4-三唑-1-基甲基)-环戊醇，通过抑制或干扰菌体附着胞及吸器的发育、菌丝和孢子的形成，还可致使膜渗漏加剧，从而降低病原菌致病力。叶菌唑是一种高效、广谱、内吸性的三唑类杀菌剂，具有保护、治疗、铲除作用，因而被广泛用于由子囊菌、担子菌等真菌引起的多种病害的防治。
氟唑菌酰胺(fluxapyroxad),化学名称：3-(二氟)-1-甲基-N-(3',4',5'-三氟[1,1'-联苯]-2-基)-1-H-吡唑-4-酰胺，氟唑菌酰胺属吡唑酰胺类杀菌剂，琥珀酸脱氢酶抑制剂，防治兼备。它能抑制真菌的呼吸作用，抑制孢子发芽，发芽管伸长，菌丝生长和孢子形成。可用于控制和抑制多种作物上的多种真菌性病害。将优越的持效性与持续的传输特性集于一体。对谷类、大豆、玉米、油料作物以及香蕉、番茄、葡萄有强效的选择性杀菌作用。
现有专利CN101595890A公开了氰烯菌酯和三唑类的农药组合物，公开了氰烯菌酯可以和三唑酮、叶菌唑、苯醚甲环唑等三唑类杀菌剂混合使用；专利CN103493818A公开了氰烯菌酯和叶菌唑的组合物，用于防治小麦赤霉病、白粉病和锈病，效果显著，可以用于延缓病原菌对三唑类杀菌剂的抗性发展；专利CN103444783A公开了氟唑菌酰胺和三唑酮、溴菌腈、氰烯菌酯等杀菌剂的组合物，用于防治赤霉病、炭疽病等；专利CN103749454A公开了氰烯菌酯和氟唑菌酰胺等的杀菌组合物，用于防治赤霉病、水稻恶苗病等。没有三者混合使用的相关报道
随着农药现代化水平的提高,现在农药面临着生态和环境问题的巨大压力。连续使用同种或同类有毒农药引起有害生物抗性增强，农民不得不采取增加用药量来加以防治，长此以往，造成恶性循环。由于新农药品种研制和生产的投资与风险越来越大，市场开发的周期越来越长，再加上有害生物抗药性发展迅速，使得有效药剂的供应越发显得短缺。而农药混配的使用在延缓有害生物的抗性、提高防效、降低成本、延长使用寿命、减少农药对环境的污染等方面均起到了重要的作用。
我们在室内筛选和田间试验的基础上，将氰烯菌酯、叶菌唑和氟唑菌酰胺进行复配，发现具有明显的增效作用，经进一步研究，完成了本发明。
发明内容
本发明要解决的技术问题是提供一种杀菌效果好、用药成本低、杀菌谱广、对小麦赤霉病、白粉病等真菌性病害具有显著增效效果的组合物。为解决上述技术问题，本发明提供技术方案如下：
一种含叶菌唑的协同减量杀菌组合物，其特征在于，氰烯菌酯、叶菌唑和氟唑菌酰胺的重量比为1-80:1-80:1-80，优选的重量比为1-50:1-50:1-50，更进一步优选为1-30:1-30:1-30，有效成分的含量为1-85％，优选20-75％。
本发明的组合物用于小麦赤霉病，小麦白粉病、小麦锈病、瓜类枯萎病、苹果炭疽病、苹果腐烂病，小麦纹枯病、水稻稻瘟病、水稻恶苗病等的防治谱内的真菌性病害的防治
本发明的组合物可以按照本技术领域技术人员所公知的方法可以配制的制剂剂型，包括水分散粒剂、可湿性粉剂、湿拌种剂、乳油、悬浮剂、油悬剂、悬乳剂、悬浮种衣剂、水乳剂、微乳剂等，在制备上述制剂时，可以根据需要在其中加入已知的助剂，例如乳化剂、润湿分散剂、助悬剂、崩解剂、粘结剂、防冻剂、增稠剂、稳定剂、消泡剂等。已知的助剂有乳化剂、润湿分散剂、助悬剂、崩解剂、粘结剂、防冻剂、增稠剂、稳定剂、消泡剂等；乳化剂例如可以是苯乙基酚聚氧乙烯聚氧丙稀醚、苯乙烯基苯酚甲醛树脂、聚氧乙烯-聚氧丙烯嵌段型聚醚、脂肪酸聚氧乙烯醚、聚氧乙烯脂肪醇醚、甘油单月桂酸酯聚氧乙烯醚、苯乙烯基苯酚聚氧乙烯醚、蓖麻油聚氧乙烯醚、乙氧基蓖麻油聚氧乙烯醚、烷基酚聚氧丙烯聚氧乙烯醚、失水山梨醇脂肪酸酯聚氧乙烯基醚、聚氧乙烯烷基酚甲醛缩合物、十二烷基磺酸钙、脂肪醇聚氧乙烯醚等中的一种或多种；分散剂可以为木质素磺酸钠、亚甲基二萘磺酸钠、木质素磺酸钙、聚丙烯酸钠、亚甲基双萘磺酸钠、亚甲基双甲基萘磺酸钠、烷基萘磺酸缩聚物的钠盐和亚甲基双萘磺酸钠甲醛缩合物等中的一种或多种；润湿剂包括十二烷基硫酸钠、十二烷基苯磺酸钠，脂肪醇聚乙二醇醚硫酸盐、脂肪醇聚氧乙烯醚、壬基酚聚氧乙烯醚、失水山梨醇脂肪酸酯聚氧乙烯醚、烷基萘甲醛缩合物、烷基萘磺酸盐、茶枯、茶皂素等的一种或多种的混合物；溶剂包括水、N-甲基吡咯烷酮、N，N-二甲基甲酰胺、磷酸三丁酯、四氢糠醇、甲苯、二甲苯、二甲基亚砜、四氢呋喃、1，4二氧六环、环己醇、环己酮、环氧大豆油、植物大豆油、液蜡、润滑油等，还可以是其他本领域常用溶剂；填料可以为白炭黑、高岭土、轻质碳酸钙、硅藻土、玉米淀粉、石英砂、滑石粉、硫酸铵、硫酸钠、氯化钠、氯化钾、轻钙等的一种或多种；防冻剂选自乙二醇、丙二醇、尿素、二甘醇、甘油等的一种或几种；增稠剂选自黄原胶、聚乙烯醇、有机膨润土、羟甲基纤维素、硅酸镁铝等的一种或几种；消泡剂可以为氮酮、有机硅类等农药中合适的助剂均可以用于本发明。
本发明的优点是明显的，主要表现在：
1、本发明的组合物，各成分之间无拮抗作用，增效作用显著。
2、本发明的组合物，扩大了杀菌谱，杀菌效果更好。
3、本发明的组合物复配增效可降低各单剂的使用量，成本低，易推广。
具体实施方式
下面结合实施例对本发明进一步的说明，实施例中的百分比均为重量比，但本发明并不局限于此。
1、室内活性测定
室内毒力测定方法为：将氰烯菌酯、叶菌唑及氟唑菌酰胺原药，根据设定的配比浓度，配置成所需的药液，备用。试验方法参考《NY/T 1156.2-2006农药室内生物测定试验准则杀菌剂第2部分：抑制病原真菌菌丝生长试验平皿法》。
在无菌条件下，将预先融化的培养基定量加入无菌锥形瓶中，从低浓度到高浓度依次定量吸取药液，分别加入上述锥形瓶，充分摇匀。然后等量倒入3个以上直径为9cm的培养皿中，制成相应浓度的含药平板。不含药剂的处理作为空白对照。重复4次。
将培养好的病原菌，在无菌条件下，用直径5mm的打孔器，自菌落边缘切取菌饼，用接种器将菌病接种于含药平板中央，菌丝面朝上，盖上皿盖，置适宜温度的培养箱培养。
根据空白对照培养皿中菌的生长情况调查病原菌菌丝生长情况，用游标卡尺测量菌落直径，十字交叉法垂直各测一次，取平均值。
菌丝生长抑制率＝(空白对照菌落直径-药剂处理菌落直径)/空白对照菌落直径×100。
采用共毒系数法评价本发明提供的含叶菌唑的协同减量杀菌组合物分别对小麦赤霉病菌、小麦白粉病菌及水稻恶苗病菌的增效作用，以药剂浓度的对数和防效几率值求回归方程，并计算得出药剂对的EC50值，然后求得共毒系数。以共毒系数评价复配药剂对小麦赤霉病、白粉病及水稻恶苗病的联合作用，共毒系数>120表示为增效作用，共毒系数在80～120之间表示为相加作用，共毒系数<80表示为拮抗作用。
表1不同配比的组合物对小麦赤霉病菌联合作用测定结果
| 药剂 | 配比 | EC<sub>50</sub>(mg/L) | 共毒系数 |
| 氰烯菌酯(简称氰) | —— | 0.14 | —— |
| 叶菌唑(简称叶) | —— | 0.04 | —— |
| 氟唑菌酰胺(简称氟) | —— | 7.36 | —— |
| 氰·叶·氟 | 1:50:30 | 0.05 | 127.54 |
| 氰·叶·氟 | 5:30:80 | 0.12 | 124.38 |
| 氰·叶·氟 | 10:1:1 | 0.10 | 124.24 |
| 氰·叶·氟 | 20:20:20 | 0.06 | 143.68 |
| 氰·叶·氟 | 30:10:50 | 0.15 | 127.81 |
| 氰·叶·氟 | 50:80:10 | 0.05 | 123.07 |
| 氰·叶·氟 | 80:5:5 | 0.10 | 131.52 |
表2不同配比的组合物对小麦白粉病菌的联合作用测定结果
| 药剂 | 配比 | EC<sub>50</sub>(mg/L) | 共毒系数 |
| 氰烯菌酯(简称氰) | —— | 35.24 | —— |
| 叶菌唑(简称叶) | —— | 1.04 | —— |
| 氟唑菌酰胺(简称氟) | —— | 11.02 | —— |
| 氰·叶·氟 | 1:50:30 | 1.29 | 123.93 |
| 氰·叶·氟 | 5:30:80 | 2.52 | 125.89 |
| 氰·叶·氟 | 10:1:1 | 5.34 | 168.22 |
| 氰·叶·氟 | 20:20:20 | 1.73 | 160.41 |
| 氰·叶·氟 | 30:10:50 | 4.86 | 123.45 |
| 氰·叶·氟 | 50:80:10 | 1.32 | 133.66 |
| 氰·叶·氟 | 80:5:5 | 7.95 | 150.24 |
表3不同配比的组合物对水稻恶苗病的联合作用测定结果
| 药剂 | 配比 | EC<sub>50</sub>(mg/L) | 共毒系数 |
| 氰烯菌酯(简称氰) | —— | 0.16 | —— |
| 叶菌唑(简称叶) | —— | 0.02 | —— |
| 氟唑菌酰胺(简称氟) | —— | 1.87 | —— |
| 氰·叶·氟 | 1:50:30 | 0.03 | 125.06 |
| 氰·叶·氟 | 5:30:80 | 0.06 | 131.35 |
| 氰·叶·氟 | 10:1:1 | 0.07 | 153.75 |
| 氰·叶·氟 | 20:20:20 | 0.03 | 170.82 |
| 氰·叶·氟 | 30:10:50 | 0.09 | 132.65 |
| 氰·叶·氟 | 50:80:10 | 0.02 | 133.22 |
| 氰·叶·氟 | 80:5:5 | 0.08 | 143.53 |
表1-3的测定结果表明，氰烯菌酯、叶菌唑和氟唑菌酰胺的组合在1-80:1-80:1-80比例范围内，对白粉病菌、赤霉病菌和水稻恶苗病菌均具有明显的增效作用，药效明显好于各自单剂单独试验效果。
2、制剂实施例
下面结合实施例对本发明进一步的说明，实施例中的百分比均为重量比，但本发明并不局限于此，本发明组合物各种剂型的加工工艺均为现有技术，根据不同情况可以有所变化。
实施例1、含氰烯菌酯、叶菌唑和氟唑菌酰胺的悬浮剂
| 成分 | 实施例1 | 对照例1 | 对照例2 | 对照例3 |
| 氰烯菌酯 | 10 | 10 | 10 | — |
| 叶菌唑 | 10 | 10 | — | 10 |
| 氟唑菌酰胺 | 10 | — | 10 | 10 |
| 烷基酚聚氧乙烯醚 | 15 | 15 | 15 | 15 |
| 木质素磺酸钙 | 5 | 5 | 5 | 5 |
| 十二烷基硫酸钠 | 5 | 5 | 5 | 5 |
| 羟乙基纤维素钠 | 2 | 2 | 2 | 2 |
| 乙二醇 | 0.5 | 0.5 | 0.5 | 0.5 |
| 水 | 补足100 | 补足100 | 补足100 | 补足100 |
实施例2、45％氰烯菌酯·叶菌唑·氟唑菌酰胺可湿性粉剂
氰烯菌酯15％，叶菌唑5％，氟唑菌酰胺25％，脂肪醇聚氧乙烯醚10％，木质素磺酸钙6％，十二烷基硫酸钠10％，硅藻土2％，丙二醇0.5％，高岭土补足100％。按照常规的制剂方法配制成质量百分含量为45％的氰烯菌酯·叶菌唑·氟唑菌酰胺可湿性粉剂。
实施例3、35％氰烯菌酯·叶菌唑·氟唑菌酰胺水分散粒剂
称取氰烯菌酯10％，叶菌唑5％，氟唑菌酰胺20％，聚羧酸盐8％，烷基萘磺酸盐甲醛缩合物7％，茶枯10％，十二烷基苯磺酸钙6％，白碳黑2％，硅藻土加至100％重量份。上述原料经常规制取水分散粒剂的方法即混合、超微气流粉碎、混合、造粒步骤制取35％的氰烯菌酯·叶菌唑·氟唑菌酰胺水分散粒剂。
实施例4、70％氰烯菌酯·叶菌唑·氟唑菌酰胺水乳剂
氰烯菌酯30％，叶菌唑30％，氟唑菌酰胺10％，亚甲基双荼磺酸钠8％，烷基酚聚氧乙烯醚6％，茶皂素13％，丙三醇0.5％，黄原胶1％，水补足100％，按照常规的制剂方法配制成质量百分含量为70％的氰烯菌酯·叶菌唑·氟唑菌酰胺水乳剂。
实施例5、60％的氰烯菌酯·叶菌唑·氟唑菌酰胺的乳油
将氰烯菌酯20％，叶菌唑30％，氟唑菌酰胺10％，十二烷基苯磺酸钙11％，脂肪醇聚氧乙烯醚5％、聚氧乙烯烷基酚甲醛缩合物7％、油酸7％、N-甲基吡咯烷酮补足100％，混合均匀，既得60％的氰烯菌酯·叶菌唑·氟唑菌酰胺乳油制剂。
3、田间药效试验
供试药剂：实施例1-5及对照例1-3中的制剂。
对照药剂：
25％氰烯菌酯悬浮剂(对照药剂1)；
60％叶菌唑可湿性粉剂(对照药剂2)；
10％氟唑菌酰胺悬浮剂(对照药剂3)。
防治作物：小麦。
防除对象：小麦赤霉病、小麦白粉病
1、赤霉病试验方法：按照试验小区的面积(约为50m2)，准确称量好各药剂，兑水稀释后，利用背负式喷雾器，于小麦扬花期第一次施药，灌浆初期第二次施药，分别于7天、15天后进行病情调查，比较各种药剂的活性。结果见表4。
表4本发明的组合物对小麦赤霉病的田间药效试验结果
2、白粉试验方法：按照试验小区的面积(约为30m2)，准确称量好各药剂，兑水稀释后，利用背负式喷雾器，于病情初期施药一次，7天后施药一次，共施药两次，末次施药7天和14天后分别调查病情指数并计算防效。结果见表5。
表5本发明的组合物对小麦白粉病的田间药效试验结果
大田试验结果表明，氰烯菌酯、叶菌唑和氟唑菌酰胺三元的复配对小麦赤霉病、白粉病的防效较好，与对照例相比，活性有了较大的提高，增效作用明显。根据田间目测，在试验剂量范围内，作物生长正常，未见植株产生药害及异常现象，对小麦安全。
以上所述是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明所述原理的前提下，还可以作出若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。
Claims (6)
1.一种含叶菌唑的协同减量杀菌组合物，其特征在于，所述的杀菌组合物以氰烯菌酯、叶菌唑和氟唑菌酰胺为有效成分，氰烯菌酯、叶菌唑和氟唑菌酰胺的重量比为1-80:1-80:1-80，氰烯菌酯、叶菌唑和氟唑菌酰胺的累积量为所述组合物总重量的1％-85％。
2.根据权利要求1的组合物，其特征在于，氰烯菌酯、叶菌唑和氟唑菌酰胺的重量比为1-50:1-50:1-50，氰烯菌酯、叶菌唑和氟唑菌酰胺的累积量为所述组合物总重量的20％-75％。
3.根据权利要求1-2任一所述的组合物，其特征在于，氰烯菌酯、叶菌唑和氟唑菌酰胺的重量比为1-30:1-30:1-30。
4.一种复合杀菌剂，其特征在于，包含权利要求1-3任一所述的组合物和农药制剂上允许的常规助剂配制成农药上允许的任意一种剂型。
5.根据权利要求4的杀菌剂，其特征在于，所述剂型为水分散粒剂、可湿性粉剂、乳油、水悬浮剂、油悬剂、悬乳剂、水乳剂、微乳剂。
6.权利要求1-3任一所述的组合物或权利要求4-5任一所述的杀菌剂用于防治小麦赤霉病，小麦白粉病、小麦锈病、瓜类枯萎病、苹果炭疽病、苹果腐烂病，小麦纹枯病、水稻稻瘟病、水稻恶苗病的应用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710387750.2A CN106962363B (zh) | 2017-05-27 | 2017-05-27 | 一种含叶菌唑的协同减量杀菌组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710387750.2A CN106962363B (zh) | 2017-05-27 | 2017-05-27 | 一种含叶菌唑的协同减量杀菌组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106962363A CN106962363A (zh) | 2017-07-21 |
| CN106962363B true CN106962363B (zh) | 2019-11-12 |
Family
ID=59326631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710387750.2A Active CN106962363B (zh) | 2017-05-27 | 2017-05-27 | 一种含叶菌唑的协同减量杀菌组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106962363B (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL2031438B1 (en) * | 2022-03-29 | 2023-10-20 | Huaiyin Inst Of Agricultural Sciences Of Xuhuai Region In Jiangsu | Synergistic decrement pesticide composition containing phenamacril and application thereof |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3124925A1 (fr) * | 2021-07-08 | 2023-01-13 | Qiuhua Huang | An use of bactericidal composition |
| AU2022468419A1 (en) * | 2022-07-05 | 2025-01-09 | Jiangsu Pesticide Research Institute Co., Ltd. | Fungicidal compositions and uses thereof in prevention and treatment of fusarium diseases of crops |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103444783B (zh) * | 2012-05-29 | 2017-07-18 | 陕西韦尔奇作物保护有限公司 | 一种含氟唑菌酰胺的杀菌组合物 |
| CN103493818A (zh) * | 2013-09-24 | 2014-01-08 | 南京农业大学 | 一种含有叶菌唑和氰烯菌酯的杀菌组合物 |
| CN105900996A (zh) * | 2016-07-12 | 2016-08-31 | 安徽省农业科学院植物保护与农产品质量安全研究所 | 一种含叶菌唑和氟唑菌酰胺的杀菌组合物 |
-
2017
- 2017-05-27 CN CN201710387750.2A patent/CN106962363B/zh active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL2031438B1 (en) * | 2022-03-29 | 2023-10-20 | Huaiyin Inst Of Agricultural Sciences Of Xuhuai Region In Jiangsu | Synergistic decrement pesticide composition containing phenamacril and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106962363A (zh) | 2017-07-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103155926B (zh) | 基于申嗪霉素的杀菌组合物 | |
| CN104886073B (zh) | 一种杀菌剂组合物和制剂及其应用 | |
| WO2022042605A1 (zh) | 一种含吡唑酰胺类化合物和三唑类杀菌剂的杀菌组合物 | |
| CN103222465B (zh) | 一种含吡唑萘菌胺和三唑类杀菌剂的杀菌组合物 | |
| CN106962363B (zh) | 一种含叶菌唑的协同减量杀菌组合物 | |
| CN103210925A (zh) | 一种含吡唑萘菌胺的杀菌组合物 | |
| CN107616178B (zh) | 一种含有zj10520和生物源杀菌剂的组合物 | |
| CN116210701A (zh) | 一种农药组合物及其应用 | |
| CN106561667A (zh) | 一种含有吡唑酰胺类杀菌剂的杀菌组合物 | |
| CN102239850A (zh) | 一种含吡氟菌酯的农用杀菌组合物 | |
| CN101019536B (zh) | 含2-氰基-3-氨基-3-苯基丙烯酸乙酯与丙环唑的杀菌组合物及其用途 | |
| CN101755761A (zh) | 基于氟喹唑的增效农药组合物 | |
| CN105900996A (zh) | 一种含叶菌唑和氟唑菌酰胺的杀菌组合物 | |
| CN105494359B (zh) | 一种防治小麦赤霉病的复配杀菌剂及其应用 | |
| CN105211082B (zh) | 一种含醚菌胺的农药组合物 | |
| NL2031438B1 (en) | Synergistic decrement pesticide composition containing phenamacril and application thereof | |
| CN104542648A (zh) | 杀菌组合物及其应用 | |
| CN104904732B (zh) | 一种含zj5337和三唑类杀菌剂的杀菌组合物 | |
| CN102696664A (zh) | 一种含嘧菌胺与三唑类的杀菌组合物 | |
| CN103355353A (zh) | 一种含嘧啶核苷类抗菌素与三唑类的杀菌组合物 | |
| CN103798258B (zh) | 一种杀菌组合物及其用途 | |
| CN103444722B (zh) | 一种含苯氧喹啉与三唑类的杀菌组合物 | |
| CN107006486A (zh) | 一种含氰烯菌酯的协同减量农药组合物及其应用 | |
| CN107087609A (zh) | 含有蒽醌类化合物与乙蒜素的杀菌剂组合物 | |
| CN107616181B (zh) | 一种含有zj10520和甲氧基丙烯酸酯类杀菌剂的组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |