CN106333711A - Living kidney tissue puncturing sampling needle - Google Patents
Living kidney tissue puncturing sampling needle Download PDFInfo
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- CN106333711A CN106333711A CN201610867733.4A CN201610867733A CN106333711A CN 106333711 A CN106333711 A CN 106333711A CN 201610867733 A CN201610867733 A CN 201610867733A CN 106333711 A CN106333711 A CN 106333711A
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- 238000005070 sampling Methods 0.000 title claims abstract description 40
- 210000005084 renal tissue Anatomy 0.000 title claims abstract description 19
- 239000007787 solid Substances 0.000 claims abstract description 12
- 239000000523 sample Substances 0.000 claims 7
- 230000035515 penetration Effects 0.000 claims 5
- 210000001519 tissue Anatomy 0.000 abstract description 21
- 230000003902 lesion Effects 0.000 abstract description 11
- 208000014674 injury Diseases 0.000 abstract description 4
- 210000000056 organ Anatomy 0.000 abstract description 4
- 230000008733 trauma Effects 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 7
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000011862 kidney biopsy Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 208000024985 Alport syndrome Diseases 0.000 description 1
- 206010029164 Nephrotic syndrome Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 208000003215 hereditary nephritis Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 201000001474 proteinuria Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
本发明公开了一种活体肾脏组织穿刺取样针,包括空心穿刺管,所述空心穿刺管前端的管壁上开设有取样孔,管内套装储样管;所述储样管前端的管壁上开设有储样槽,槽的边缘开刃;所述取样孔与储样槽在相同轴向位置;空心穿刺管端部为实心尖头结构。通过旋转中间的旋切管,将陷入储样槽中的样本与本体分离,创伤面积小。空心穿刺管端部为实心尖头结构,可避免刺入病灶器官时组织细胞进入储样管与空心穿刺管之间夹缝,利于穿刺。本发明能较好解决现有肾脏组织穿刺取样针操作繁杂、内部创伤大的问题。
The invention discloses a living kidney tissue puncture sampling needle, which comprises a hollow puncture tube, a sampling hole is opened on the tube wall at the front end of the hollow puncture tube, and a sample storage tube is set inside the tube; There is a sample storage tank, and the edge of the tank is sharpened; the sampling hole and the sample storage tank are at the same axial position; the end of the hollow puncture tube is a solid pointed structure. By rotating the rotary cutting tube in the middle, the sample trapped in the sample storage tank is separated from the main body, and the trauma area is small. The end of the hollow puncture tube is a solid pointed structure, which can prevent tissue cells from entering the gap between the sample storage tube and the hollow puncture tube when piercing into the lesion organ, which is convenient for puncture. The invention can better solve the problems of complicated operation and large internal trauma of the existing kidney tissue puncture sampling needle.
Description
技术领域technical field
本发明涉及活体取样装置技术领域,特别涉及一种活体肾脏组织穿刺取样针。The invention relates to the technical field of living body sampling devices, in particular to a living body kidney tissue puncture sampling needle.
背景技术Background technique
在临床研究和诊断中,常采用活体取样的方法对要研究或是诊断的部位进行采样。即对要研究或者分析的部位或组织进行取样,然后将取出的样本进行培养和检验,获得具有说服力和针对性的结果或结论。在提取少量样本的应用中,活体取样针是一种重要的器械,因其创面小、操作灵活被广泛接受。In clinical research and diagnosis, living body sampling is often used to sample the part to be studied or diagnosed. That is to take samples of the parts or tissues to be studied or analyzed, and then culture and test the taken samples to obtain convincing and targeted results or conclusions. In the application of extracting a small amount of samples, the biopsy needle is an important device, which is widely accepted for its small wound and flexible operation.
肾脏是人体重要的代谢器官,肾穿刺活体组织检查术简称肾活检,用以明确肾脏疾病性质和病理类型、确定治疗方针、判定预后的重要检查方法。可适用于无症状性血尿、蛋白尿、急性肾炎治疗、原发性肾病综合征、继发性或遗传性肾炎等多种症状的治疗。The kidney is an important metabolic organ of the human body. Kidney biopsy, referred to as kidney biopsy, is an important examination method to clarify the nature and pathological types of kidney diseases, determine treatment guidelines, and determine prognosis. It can be applied to the treatment of various symptoms such as asymptomatic hematuria, proteinuria, acute nephritis, primary nephrotic syndrome, secondary or hereditary nephritis.
现有中国专利CN201010154334.6提供一种用于骨穿刺活动组织检查的活检针组合,包括实心穿刺针,具有锥管状前端的空心管取样针,和设于针管壁上的平行于针管轴的截面开口,以及设于截面开口一边沿针管圆周切向延伸出的切割刀。The existing Chinese patent CN201010154334.6 provides a biopsy needle combination for bone puncture and examination of active tissues, including a solid puncture needle, a hollow tube sampling needle with a tapered tubular front end, and a needle tube parallel to the axis of the needle tube. A section opening, and a cutting knife arranged on one side of the section opening and extending tangentially along the circumference of the needle tube.
但是上述技术使用较为复杂,首先要将实心穿刺针与工作通道套管配合插入组织,后将实心穿刺针取出,将空心管取样针从工作通道导管尾端插入,旋转空心管取样针使目的样本与组织分离,拔出空心管取样针后用铜条吸取其内部的样本。该技术操作复杂,且用铜条吸取其内部的样本路程较远,对样本可能造成一定损坏。However, the above-mentioned technique is relatively complicated to use. First, the solid puncture needle and the working channel cannula must be inserted into the tissue, and then the solid puncture needle should be taken out, and the hollow tube sampling needle should be inserted from the end of the working channel catheter, and the hollow tube sampling needle should be rotated to make the target sample Separated from the tissue, pull out the hollow tube sampling needle and use a copper strip to draw the sample inside it. The operation of this technique is complicated, and it takes a long distance to absorb the sample inside it with a copper strip, which may cause some damage to the sample.
发明内容Contents of the invention
本发明的目的在于提供一种活体肾脏组织穿刺取样针,解决现有肾脏组织穿刺取样针操作繁杂、内部创伤大的问题。The object of the present invention is to provide a living kidney tissue puncture sampling needle, which solves the problems of complicated operation and large internal trauma of the existing kidney tissue puncture sampling needle.
为实现上述目的,达到上述技术效果,本发明通过以下技术方案解决上述问题:In order to achieve the above object and achieve the above technical effect, the present invention solves the above problem through the following technical solutions:
一种活体肾脏组织穿刺取样针,包括空心穿刺管,所述空心穿刺管前端的管壁上开设有取样孔,管内套装储样管;所述储样管前端的管壁上开设有储样槽,槽的边缘开刃;所述取样孔与储样槽在相同轴向位置。A living kidney tissue puncture sampling needle, comprising a hollow puncture tube, a sampling hole is opened on the tube wall at the front end of the hollow puncture tube, and a sample storage tube is set in the tube; a sample storage tank is opened on the tube wall at the front end of the sample storage tube , the edge of the groove is sharpened; the sampling hole and the storage tank are at the same axial position.
本发明所述的取样针为环套型针体,从内到外依次为储样管、空心穿刺管,储样管和空心穿刺管前端对应位置分别开有储样槽和取样孔,储样管可绕其共同轴线旋转。将刀刃结构设于储样槽槽口,在转动储样槽的同时便能对取样孔中的病灶进行切割,切割后的组织可存储于储样槽中。The sampling needle of the present invention is a ring-shaped needle body, which is sequentially composed of a sample storage tube and a hollow puncture tube from the inside to the outside. The tubes are rotatable about their common axis. The blade structure is arranged at the notch of the sample storage tank, and the lesion in the sampling hole can be cut while the sample storage tank is rotated, and the cut tissue can be stored in the sample storage tank.
将针体插入病灶组织部位,由于压力和组织间的相互作用,部分病灶组织会陷于取样孔凹孔内,旋转储样管,利用储样槽边缘的刀刃结构,实现样品组织与本体的分离。此法较现有将切割刀延伸至空心管外部旋切病灶的方法,创面较小,切割产物提取率高。Insert the needle into the lesion tissue, due to the interaction between the pressure and the tissue, part of the lesion tissue will be trapped in the concave hole of the sampling hole, rotate the sample storage tube, and use the blade structure on the edge of the sample storage tank to separate the sample tissue from the body. Compared with the existing method of extending the cutting knife to the outside of the hollow tube and rotary cutting the lesion, this method has smaller wounds and a higher extraction rate of cutting products.
作为本发明上述一种活体肾脏组织穿刺取样针的改进,所述空心穿刺管前端为实心尖头结构,储样管顶端与实心尖头结构内侧接触。这样一来,可避免刺入病灶器官时组织细胞进入储样管与空心穿刺管之间夹缝,影响储样管和空心穿刺管的相对转动;同时穿刺段一体化设计可以保持端面光滑,利于穿刺。As an improvement of the aforementioned living kidney tissue puncture sampling needle of the present invention, the front end of the hollow puncture tube is a solid pointed structure, and the top of the sample storage tube is in contact with the inner side of the solid pointed structure. In this way, tissue cells can be prevented from entering the gap between the sample storage tube and the hollow puncture tube when puncturing into the lesion organ, which will affect the relative rotation of the sample storage tube and the hollow puncture tube; at the same time, the integrated design of the puncture section can keep the end surface smooth and facilitate puncture .
作为本发明上述一种活体肾脏组织穿刺取样针的改进,所述取样孔为弧形凹孔。病灶组织由于体内压力和细胞间相互作用的影响在取样孔内形成凸面,设计弧状凹孔能使更多的组织进入槽内,同时也可避免病变硬块组织无法进入取样孔的情况。As an improvement of the aforementioned living kidney tissue puncture sampling needle of the present invention, the sampling hole is an arc-shaped concave hole. The lesion tissue forms a convex surface in the sampling hole due to the influence of the pressure in the body and the interaction between cells. The design of the arc-shaped concave hole can allow more tissue to enter the groove, and can also avoid the situation that the diseased hard tissue cannot enter the sampling hole.
作为本发明上述一种活体肾脏组织穿刺取样针的改进,所述储样管尾部穿过空心穿刺管管口,尾端设置有旋柄。设置超过空心穿刺管管身的储样管以及尾端的旋柄,利于旋转操作。As an improvement of the above-mentioned living kidney tissue puncture sampling needle of the present invention, the tail of the sample storage tube passes through the mouth of the hollow puncture tube, and the tail end is provided with a rotating handle. The sample storage tube beyond the hollow puncture tube body and the rotary handle at the end are arranged to facilitate the rotation operation.
作为本发明上述一种活体肾脏组织穿刺取样针的改进,所述储样管尾部管壁设置限位滑块,空心穿刺管尾端内壁设置与限位滑块对应的限位槽。通过滑块控制储样管绕空心穿刺管,能保证穿刺过程中储样管和空心穿刺管相对位置固定,防止非目的组织进入槽中,同时也能防止在抽出过程中目的组织从槽口滑落。As an improvement of the living kidney tissue puncture sampling needle of the present invention, a limit slider is provided on the wall of the tail of the sample storage tube, and a limit groove corresponding to the limit slider is provided on the inner wall of the tail end of the hollow puncture tube. Control the sample storage tube around the hollow puncture tube through the slider, which can ensure that the relative position of the sample storage tube and the hollow puncture tube is fixed during the puncture process, prevent non-target tissues from entering the groove, and prevent the target tissue from slipping from the groove during the extraction process. .
本发明的有益效果是:The beneficial effects of the present invention are:
1、通过旋转中间的储样管,将陷入储样槽中样本与本体分离,较现有将切割刀延伸至空心管外部旋切病灶而言创面小。1. By rotating the sample storage tube in the middle, the sample trapped in the sample storage tank is separated from the body, which is smaller than the existing cutting knife extended to the external hollow tube to rotary cut the lesion.
2、空心穿刺管前端为实心尖头结构,储样管顶端与实心尖头结构内侧接触,可避免刺入病灶器官时组织细胞进入储样管与空心穿刺管之间夹缝,影响储样管和空心穿刺管的相对转动,能保持端面光滑,利于穿刺。2. The front end of the hollow puncture tube is a solid pointed structure, and the top of the sample storage tube is in contact with the inner side of the solid pointed structure, which can prevent tissue cells from entering the gap between the sample storage tube and the hollow puncture tube when piercing into the lesion organ, affecting the storage tube and the hollow puncture tube. The relative rotation of the hollow puncture tube can keep the end surface smooth and facilitate puncture.
3、设计弧状凹孔使更多的组织滑入槽内,提高储样槽的利用率。3. The arc-shaped concave hole is designed to allow more tissue to slide into the tank, improving the utilization rate of the sample storage tank.
本发明能较好解决现有肾脏组织穿刺取样针操作繁杂、内部创伤大的问题。The invention can better solve the problems of complicated operation and large internal trauma of the existing kidney tissue puncture sampling needle.
附图说明Description of drawings
图1为一种活体肾脏组织穿刺取样针剖面图;Fig. 1 is a sectional view of a living kidney tissue puncture sampling needle;
图2为空心穿刺管示意图;Fig. 2 is a schematic diagram of a hollow puncture tube;
图3为储样管示意图;Fig. 3 is a schematic diagram of a sample storage tube;
图4为沿图1中A-A线的剖视图。Fig. 4 is a sectional view along line A-A in Fig. 1 .
图号标识:10、空心穿刺管,11、取样孔,12、手柄,121、限位槽,20、储样管,21、储样槽,211、刃,22、旋柄,23、限位滑块,24、滑块槽。Drawing number identification: 10, hollow puncture tube, 11, sampling hole, 12, handle, 121, limit slot, 20, sample storage tube, 21, sample storage tank, 211, blade, 22, rotary handle, 23, limit Slide block, 24, slide block groove.
具体实施方式detailed description
以下结合实施例对本发明作进一步说明,但本发明并不局限于以下实施例。The present invention will be further described below in conjunction with the examples, but the present invention is not limited to the following examples.
本实例所述一种活体肾脏组织穿刺取样针,如附图1和附图4所示,针体为圆柱环套型结构,从内到外依次为储样管20、空心穿刺管10。A living kidney tissue puncture sampling needle described in this example, as shown in accompanying drawings 1 and 4, the needle body is a cylindrical ring-shaped structure, and from the inside to the outside are a sample storage tube 20 and a hollow puncture tube 10 in sequence.
如附图1和附图2所示,针体最外部的空心穿刺管10呈尾部开口的中空结构,前端的管壁上开设有弧形取样孔11,尾部设置有环状手柄12。其前端为实心尖头结构,用于穿刺肌肤或组织皮层。空心穿刺管10的环状手柄12尾部开有限位槽121。As shown in accompanying drawings 1 and 2, the outermost hollow puncture tube 10 of the needle body is a hollow structure with an open tail, an arc-shaped sampling hole 11 is opened on the tube wall at the front end, and a ring-shaped handle 12 is provided at the tail. Its front end is a solid pointed structure, which is used to puncture the skin or tissue cortex. The end of the ring handle 12 of the hollow puncture tube 10 is provided with a limiting groove 121 .
如附图1和附图3所示,柱状储样管20前部开有与空心穿刺管10前部弧形取样孔11位置对应的储样槽21,储样槽21边缘两侧开刃211。储样管20尾部长于空心穿刺管10,并在尾端设置有旋柄22。As shown in accompanying drawings 1 and 3, the front part of the columnar sample storage tube 20 is provided with a sample storage tank 21 corresponding to the position of the arc-shaped sampling hole 11 at the front part of the hollow puncture tube 10, and both sides of the edge of the sample storage tank 21 have edges 211 . The tail of the sample storage tube 20 is longer than the hollow puncture tube 10, and a handle 22 is provided at the tail end.
如附图1、附图2、附图3所示,储样管20尾部与空心穿刺管10接触部位开设有滑块槽24,限位滑块23可滑动安装于其中。旋转储样管20将滑块槽24调整到与限位槽121对应位置,将限位滑块23滑入限位槽121中,实现储样管20和空心穿刺管10之间的固定,防止储样管20与空心穿刺管10相对转动。As shown in accompanying drawings 1 , 2 and 3 , a slider groove 24 is provided at the contact portion between the tail of the sample storage tube 20 and the hollow puncture tube 10 , and the limit slider 23 can be slidably installed therein. Rotate the sample storage tube 20 to adjust the slider groove 24 to the position corresponding to the limit groove 121, and slide the limit slider 23 into the limit groove 121 to realize the fixation between the sample storage tube 20 and the hollow puncture tube 10, preventing The sample storage tube 20 and the hollow puncture tube 10 rotate relatively.
本实施例的工作原理为:The working principle of this embodiment is:
将储样管20装配入空心穿刺管10,将滑块槽24调整到与限位槽121对应位置,将限位滑块23滑入限位槽121中,此时储样槽21槽口被空心穿刺管10覆盖。Assemble the sample storage tube 20 into the hollow puncture tube 10, adjust the slider groove 24 to the position corresponding to the limit groove 121, slide the limit slider 23 into the limit groove 121, and at this time, the notch of the sample storage tank 21 is closed. The hollow puncture tube 10 covers.
待针体刺入病灶部位后将限位滑块23滑出限位槽121,旋转储样管20使储样槽21与取样孔11连通,部分病灶组织陷于储样槽21的中,旋转储样管20上的刃211进行切割,实现样品组织与本体的分离。After the needle penetrates into the lesion, slide the limit slider 23 out of the limit groove 121, rotate the sample storage tube 20 to connect the sample storage tank 21 with the sampling hole 11, part of the lesion tissue is trapped in the sample storage tank 21, and rotate the storage tube 20 to connect the sample storage tank 21 with the sampling hole 11. The blade 211 on the sample tube 20 cuts to realize the separation of the sample tissue and the body.
旋转储样管20封闭储样槽21,将限位滑块23滑入限位槽121中,可防止样品掉出。最后将存储样品的针体抽出,提取储样槽21中的样品可作检验用。Rotate the sample storage tube 20 to close the sample storage tank 21, and slide the limit slider 23 into the limit groove 121 to prevent the sample from falling out. Finally, the needle body storing the sample is drawn out, and the sample in the sample storage tank 21 is extracted for inspection.
以上结合附图对本发明的实施方式详细说明,但本发明不局限于所描述的实施方式。对于本领域的技术人员而言,在不脱离本发明的原理和精神的情况下对这些实施方式进行多种变化、修改、替换和变型仍落入本发明的保护范围内。The embodiments of the present invention have been described in detail above with reference to the accompanying drawings, but the present invention is not limited to the described embodiments. For those skilled in the art, without departing from the principle and spirit of the present invention, various changes, modifications, substitutions and modifications to these embodiments still fall within the protection scope of the present invention.
Claims (5)
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CN108433755A (en) * | 2018-04-13 | 2018-08-24 | 河南科技大学第附属医院 | A kind of tumor sampling device |
CN109171824A (en) * | 2018-07-16 | 2019-01-11 | 郑州大学第附属医院 | A kind of liver biopsy puncture needle and its application method |
CN109893175A (en) * | 2019-02-28 | 2019-06-18 | 成都真实维度科技有限公司 | A kind of device carrying out aspiration biopsy by laser aiming |
CN110811699A (en) * | 2019-10-25 | 2020-02-21 | 台州市立医院 | Tumor sample sampling device |
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CN108433755A (en) * | 2018-04-13 | 2018-08-24 | 河南科技大学第附属医院 | A kind of tumor sampling device |
CN109171824A (en) * | 2018-07-16 | 2019-01-11 | 郑州大学第附属医院 | A kind of liver biopsy puncture needle and its application method |
CN109893175A (en) * | 2019-02-28 | 2019-06-18 | 成都真实维度科技有限公司 | A kind of device carrying out aspiration biopsy by laser aiming |
CN110811699A (en) * | 2019-10-25 | 2020-02-21 | 台州市立医院 | Tumor sample sampling device |
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CN111616749A (en) * | 2020-06-04 | 2020-09-04 | 中国人民解放军西部战区总医院 | Liver biopsy puncture needle capable of sampling multiple depths simultaneously |
CN112690835A (en) * | 2020-12-23 | 2021-04-23 | 重庆市公共卫生医疗救治中心 | AIDS lung puncture biopsy device and use method thereof |
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