CN101879079B - Biopsy needle - Google Patents
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- CN101879079B CN101879079B CN201010214737.5A CN201010214737A CN101879079B CN 101879079 B CN101879079 B CN 101879079B CN 201010214737 A CN201010214737 A CN 201010214737A CN 101879079 B CN101879079 B CN 101879079B
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- 238000001574 biopsy Methods 0.000 title claims abstract description 39
- 238000005070 sampling Methods 0.000 claims abstract description 62
- 239000000523 sample Substances 0.000 claims abstract description 8
- 238000010276 construction Methods 0.000 claims 1
- 230000036413 temperature sense Effects 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 5
- 238000003745 diagnosis Methods 0.000 abstract description 4
- 230000000472 traumatic effect Effects 0.000 abstract description 2
- 230000006698 induction Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 description 14
- 238000000034 method Methods 0.000 description 8
- 230000006378 damage Effects 0.000 description 5
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- 208000002151 Pleural effusion Diseases 0.000 description 4
- 210000000683 abdominal cavity Anatomy 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 206010003445 Ascites Diseases 0.000 description 2
- 206010054827 Peritoneal lesion Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 210000004224 pleura Anatomy 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 208000012260 Accidental injury Diseases 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010026673 Malignant Pleural Effusion Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 210000003567 ascitic fluid Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000013276 bronchoscopy Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
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- 230000004054 inflammatory process Effects 0.000 description 1
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- 238000002350 laparotomy Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 210000004910 pleural fluid Anatomy 0.000 description 1
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- 208000024794 sputum Diseases 0.000 description 1
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Abstract
本发明提供了一种活检针，包括针管、温度感应装置和取样装置；针管靠近针尖一端的针壁上沿轴向开有一个凹槽，凹槽中部沿圆周方向有一圆环形凹槽；温度感应装置温度感应器的中部铰接于凹槽顶部的针管内壁上形成杠杆结构，温度感应器一端连接温度感应探头，另一端与连接杆的上端铰接，连接杆的下端与温度感应器控制杆的上端铰接，温度感应器控制杆的下端连接温度显示器；取样装置包括取样筒、取样刀和取样刀控制杆，取样筒垂直固定在温度感应器的中部且开口向下，取样刀呈与圆周方向的环形凹槽相适形的圆弧形，取样刀控制杆上端与取样刀相连，下端与旋转按钮相连接；本活检针操作方便，创伤小，取材更有针对性，提高诊断率。
The invention provides a biopsy needle, comprising a needle tube, a temperature sensing device and a sampling device; a groove is formed on the needle wall of the needle tube near the needle point along the axial direction, and a circular groove is arranged in the middle of the groove along the circumferential direction; the temperature Induction device The middle part of the temperature sensor is hinged on the inner wall of the needle tube at the top of the groove to form a lever structure. One end of the temperature sensor is connected to the temperature sensing probe, the other end is hinged to the upper end of the connecting rod, and the lower end of the connecting rod is connected to the upper end of the temperature sensor control rod. Hinged, the lower end of the temperature sensor control rod is connected to the temperature display; the sampling device includes a sampling cylinder, a sampling knife and a sampling knife control rod, the sampling cylinder is vertically fixed in the middle of the temperature sensor with the opening downward, and the sampling knife is in the shape of a ring in the circumferential direction The groove conforms to the arc shape of the shape, the upper end of the sampling knife control rod is connected with the sampling knife, and the lower end is connected with the rotation button; the biopsy needle is easy to operate, less traumatic, more targeted for material collection, and improves the diagnosis rate.
Description
技术领域technical field
本发明涉及一种医疗器械，特别涉及一种活检针。The invention relates to a medical device, in particular to a biopsy needle.
背景技术Background technique
胸腔或腹腔积液是临床多见病、常发病，因其病因繁多，很难快速准确的诊断，进而影响后续的治疗，给患者及其家属造成经济和健康的损失，甚至造成病情的延误、恶化。目前临床常规对病因诊断主要依靠经胸水常规生化、X线及CT、胸水及痰细胞学检查、纤维支气管镜检查等，对于大部分患者可协助作出病因诊断，但仍有部分患者不能确诊，临床上也常遇到此类患者，很难确定其病因，据文献报道大约在10%～20%。Pleural or peritoneal effusion is a common clinical disease and often occurs. Because of its various causes, it is difficult to diagnose quickly and accurately, which in turn affects subsequent treatment, causing economic and health losses to patients and their families, and even delays in treatment. deterioration. At present, routine clinical diagnosis of etiology mainly relies on routine biochemistry of transpleural effusion, X-ray and CT, pleural effusion and sputum cytology, fiberoptic bronchoscopy, etc., which can assist in making etiological diagnosis for most patients, but there are still some patients who cannot be diagnosed. Such patients are often encountered in the Internet, and it is difficult to determine the etiology. According to literature reports, it is about 10% to 20%.
胸膜活检具有简便、快速、患者易于接受等优点，可有效提高胸腔积液病因的诊断率。但是现有的胸膜活检也存在诸多缺点和局限性：胸腔积液时由于胸膜病变并非均匀一致，病变多局限于胸膜某一部位或灶性分布，胸膜活检在非直视下进行，盲目性大，临床高度怀疑恶性胸水在胸膜上不是弥漫分布，有时需在不同部位多次活检才能取得阳性结果，传统的胸膜活检针一次取材量较少，也限制了准确性，假阴性率可达40%以上，有时甚至需要多次取材，给患者造成身体和经济的损失。传统活检针因进针需要较深，胸水量少时可能损伤肺组织，而且取材深度不能控制，只能通过手感和术者的经验，也容易造成损伤。Pleural biopsy has the advantages of simplicity, rapidity, and easy acceptance by patients, which can effectively improve the diagnosis rate of the etiology of pleural effusion. However, the existing pleural biopsy also has many shortcomings and limitations: in the case of pleural effusion, the pleural lesions are not uniform, and the lesions are mostly limited to a certain part of the pleura or focal distribution. , It is highly suspected that malignant pleural effusion is not diffusely distributed on the pleura, and sometimes multiple biopsies at different parts are required to obtain a positive result. The traditional pleural biopsy needle takes less material at one time, which also limits the accuracy, and the false negative rate can reach 40%. Above, sometimes even need to draw materials repeatedly, cause physical and economic loss to the patient. The traditional biopsy needle needs to be inserted deep, and the lung tissue may be damaged when the amount of pleural fluid is small, and the depth of the biopsy cannot be controlled.
现阶段获得腹膜组织标本的方法有：剖腹手术探查和腹腔镜下取材，对于这两项技术，患者均要承担麻醉和手术的风险，不宜普及应用；腹水细胞学检查阳性率较低；传统的钩式针腹膜活检，取材组织少，盲目性大，诊断准确性不高，也容易发生损伤、出血等并发症。另一方面，腹膜病变厚薄不一，有的很薄，穿刺易穿透；有的腹膜病变位于内脏深部，穿刺难穿到。所以，现有的腹膜活检针很难保证准确安全地穿刺到腹膜组织，也不能保证腹膜组织标本量够多，又不损伤到周围的脏器，如肠管等等。At present, the methods for obtaining peritoneal tissue samples include: laparotomy exploration and laparoscopic sampling. For these two techniques, patients have to bear the risk of anesthesia and surgery, and should not be widely used; the positive rate of ascites cytology is low; the traditional method Hook-needle peritoneal biopsy requires few tissues, high blindness, low diagnostic accuracy, and is prone to complications such as injury and bleeding. On the other hand, peritoneal lesions vary in thickness, some are very thin and easy to penetrate by puncture; some peritoneal lesions are located deep in the viscera and difficult to penetrate. Therefore, it is difficult for the existing peritoneal biopsy needles to accurately and safely puncture the peritoneal tissue, nor can it ensure that the sample volume of the peritoneal tissue is large enough without damaging the surrounding organs, such as intestinal tubes and the like.
针对上述不足，需探索一种新的活检针，使其在保留原有功能的基础上，改善和克服上述缺点。In view of the above-mentioned shortcomings, it is necessary to explore a new biopsy needle to improve and overcome the above-mentioned shortcomings on the basis of retaining the original functions.
发明内容Contents of the invention
有鉴于此，本发明提供一种活检针，能够找到病变组织的准确位置，增加病变组织的取样量，避免多次穿刺带来的损伤，同时还避免对周围脏器的误伤，保证了穿刺的安全性。In view of this, the present invention provides a biopsy needle, which can find the exact location of the diseased tissue, increase the sampling volume of the diseased tissue, avoid damage caused by multiple punctures, and avoid accidental injury to surrounding organs at the same time, ensuring the accuracy of the puncture. safety.
本发明的目的是通过以下技术方案实现的:一种活检针，包括针管、温度感应装置和取样装置；The object of the present invention is achieved by the following technical solutions: a biopsy needle, comprising a needle tube, a temperature sensing device and a sampling device;
所述针管靠近针尖一端的针管壁上沿轴向开有通孔，靠近针尖端的针管壁上沿圆周方向还设置有一环形凹槽；A through hole is opened in the axial direction on the wall of the needle tube near the end of the needle tip, and an annular groove is also arranged on the wall of the needle tube near the needle tip along the circumferential direction;
所述温度感应装置包括温度感应器、温度感应器控制杆和连接温度感应器和温度感应器控制杆的连接杆，温度感应器的中部铰接于通孔顶部的针管壁上形成杠杆结构，温度感应器一端连接有温度感应探头，另一端铰接于连接杆的上端，连接杆的下端铰接于温度感应器控制杆的上端，温度感应器控制杆的下端连接温度显示器；The temperature sensing device comprises a temperature sensor, a temperature sensor control rod and a connecting rod connecting the temperature sensor and the temperature sensor control rod, the middle part of the temperature sensor is hinged on the needle tube wall at the top of the through hole to form a lever structure, and the temperature One end of the sensor is connected with a temperature sensing probe, the other end is hinged to the upper end of the connecting rod, the lower end of the connecting rod is hinged to the upper end of the temperature sensor control rod, and the lower end of the temperature sensor control rod is connected to the temperature display;
所述取样装置包括取样筒、取样刀和取样刀控制杆，取样筒垂直固定设置在温度感应器上，温度感应器被展开时取样筒的开口端面与环形凹槽平齐，取样刀为月牙形且位于环形凹槽内，取样刀控制杆以可绕其轴线转动的方式单自由度设置于针管内，取样刀控制杆一端与取样刀的刀柄固定连接，另一端固定连接有旋转按钮。The sampling device includes a sampling cylinder, a sampling knife and a sampling knife control rod. The sampling cylinder is fixed vertically on the temperature sensor. When the temperature sensor is unfolded, the opening end face of the sampling cylinder is flush with the annular groove, and the sampling knife is crescent-shaped. And located in the annular groove, the sampling knife control rod is arranged in the needle tube with a single degree of freedom in a manner that can rotate around its axis. One end of the sampling knife control rod is fixedly connected with the handle of the sampling knife, and the other end is fixedly connected with a rotation button.
进一步，所述通孔、温度感应装置和取样装置为多个且沿圆周方向均匀分布；Further, there are multiple through holes, temperature sensing devices and sampling devices and they are evenly distributed along the circumferential direction;
进一步，所述活检针尾端设置有控制杆固定盖；Further, the tail end of the biopsy needle is provided with a control rod fixing cover;
进一步，所述活检针的针尖以可沿针管轴向移动的方式内套于针管内，针管内沿轴向还设置有针尖控制杆，针尖控制杆与针尖固定连接，控制杆固定盖的针尖控制杆固定孔上设置有内螺纹，针尖控制杆上设置有与内螺纹相配合的外螺纹。Further, the needle point of the biopsy needle is sheathed in the needle tube in a manner that can move along the axial direction of the needle tube. A needle point control rod is also arranged in the needle tube along the axial direction. The rod fixing hole is provided with an internal thread, and the needle point control rod is provided with an external thread matched with the internal thread.
本发明的有益效果是：本发明的活检针设置了温度传感器，由于人体病变部位会发生血流改变，可出现与正常组织不同的温度，当温度传感器的探头探测到病变组织后，通过温度传感器的显示器显示出来，以示准确找到了肿瘤或炎症等病变位置，即可通过本活检针的取样装置准确取样；本发明专门设置取样装置，由于采用较大体积的取样筒进行取样，较传统取样方法获取的组织标本量大、取材多，便于获得更好的阳性结果，避免了因量少而重复穿刺而给患者造成的损伤；本发明的活检针还设置了可伸缩调节的针尖，在穿透后可立即将针尖缩回针管内，避免了在取样过程中可能对肠管等内脏造成损害，大大提高了穿刺取样的安全性；因此本发明的活检针操作方便，创伤小，更有针对性的取材，提高诊断率，同时大大提高了穿刺取样的安全性。The beneficial effect of the present invention is that: the biopsy needle of the present invention is provided with a temperature sensor, because the blood flow of the diseased part of the human body will change, and the temperature different from that of the normal tissue may appear. The display of the biopsy needle is displayed to show that the location of the lesion such as tumor or inflammation has been accurately found, and the sampling device of the biopsy needle can be used to accurately sample; the present invention is specially equipped with a sampling device. The amount of tissue samples obtained by the method is large, and many materials are taken, which is convenient for obtaining better positive results, and avoids the damage caused to the patient due to repeated puncture due to a small amount; Immediately after penetration, the needle tip can be retracted into the needle tube, which avoids possible damage to intestines and other internal organs during the sampling process, and greatly improves the safety of puncture sampling; therefore, the biopsy needle of the present invention is easy to operate, less traumatic, and more targeted It improves the diagnosis rate and greatly improves the safety of puncture sampling.
附图说明Description of drawings
下面结合附图和实施例对本发明作进一步描述；The present invention will be further described below in conjunction with accompanying drawing and embodiment;
附图1为本发明的结构剖视图；Accompanying drawing 1 is a structural sectional view of the present invention;
附图2为本发明取样刀的外形图。Accompanying drawing 2 is the outline drawing of sampling knife of the present invention.
具体实施方式Detailed ways
附图1为本发明的结构示意图，附图2为本发明取样刀的外形图。如图1所示，本发明所涉及的活检针，包括针管1、温度感应装置和取样装置；所述针管1靠近针尖一端的针管壁上沿轴向开有通孔2，靠近针尖端的针管壁上沿圆周方向还设置有一环形凹槽3；所述温度感应装置包括温度感应器4、温度感应器控制杆7和连接温度感应器4和温度感应器控制杆7的连接杆6，温度感应器4的中部铰接于通孔2顶部的针管壁上形成杠杆结构，温度感应器4一端连接有温度感应探头5，另一端铰接于连接杆6的上端，连接杆6的下端铰接于温度感应器控制杆7的上端，温度感应器控制杆7的下端连接温度显示器8；所述取样装置包括取样筒9、取样刀10和取样刀控制杆11，取样筒9垂直固定设置在温度感应器4上，温度感应器4被展开时取样筒的开口端面与环形凹槽3平齐，取样刀10为月牙形且位于环形凹槽3内，取样刀控制杆11以可绕其轴线转动的方式单自由度设置于针管内，取样刀控制杆11一端与取样刀10的刀柄固定连接，另一端固定连接有旋转按钮。Accompanying drawing 1 is a schematic structural view of the present invention, and accompanying drawing 2 is an outline drawing of a sampling knife of the present invention. As shown in Figure 1, the biopsy needle involved in the present invention includes a needle tube 1, a temperature sensing device and a sampling device; the needle tube wall at the end of the needle tube 1 near the needle tip has a through hole 2 in the axial direction, and the needle tube wall near the needle tip An annular groove 3 is also arranged on the needle tube wall along the circumferential direction; the temperature sensing device includes a temperature sensor 4, a temperature sensor control rod 7 and a connecting rod 6 connecting the temperature sensor 4 and the temperature sensor control rod 7, The middle part of the temperature sensor 4 is hinged on the needle tube wall at the top of the through hole 2 to form a lever structure. One end of the temperature sensor 4 is connected with a temperature sensing probe 5, and the other end is hinged at the upper end of the connecting rod 6. The lower end of the connecting rod 6 is hinged at the The upper end of the temperature sensor control rod 7, the lower end of the temperature sensor control rod 7 is connected to the temperature display 8; the sampling device includes a sampling cylinder 9, a sampling knife 10 and a sampling knife control rod 11, and the sampling cylinder 9 is vertically fixed on the temperature sensor. On the device 4, when the temperature sensor 4 is unfolded, the opening end face of the sampling cylinder is flush with the annular groove 3, the sampling knife 10 is crescent-shaped and is located in the annular groove 3, and the sampling knife control rod 11 can rotate around its axis. The mode single degree of freedom is set in the needle tube, one end of the sampling knife control rod 11 is fixedly connected with the handle of the sampling knife 10, and the other end is fixedly connected with a rotation button.
本发明的使用方法为：使用前，推动温度感应器控制杆7，使温度感应器4置于通孔2内，月牙形取样刀10置于环形凹槽3内，当活检针扎入腹腔内后，沿径向向外拉动温度感应器控制杆7，使温度感应器4完全展开，往回缓慢拉动活检针，使温度感应探头紧贴腹腔内壁，观察温度显示器8，当发现温度与正常温度相差较大时，说明找到了病变部位，此时再沿活检针的轴向往外用力拉动活检针，使腹腔内壁病变部位的组织进入取样筒9内，之后转动取样刀10，使取样刀10沿取样筒9的筒口面划过取样筒，割取残留在取样筒内的病变组织；然后再沿活检针轴向往里推动活检针，往回转动取样刀10，将其置于圆环形凹槽3内，推动温度感应器控制杆7，将温度感应器4返回凹槽2内，缓慢将活检针抽出患者体内，最后取出取样筒9内的病变组织，最终达到取样的目的。采用本发明的活检针，不仅能够应用温度感应器准确定位取样，而且还专门设置取样筒，较传统取样方法获取的组织标本量大、取材多，便于获得更好的阳性结果，避免了因量少而重复穿刺而给患者造成的损伤。The use method of the present invention is: before use, push the temperature sensor control lever 7, place the temperature sensor 4 in the through hole 2, place the crescent-shaped sampling knife 10 in the annular groove 3, and when the biopsy needle is inserted into the abdominal cavity Finally, pull the temperature sensor control rod 7 radially outwards to fully expand the temperature sensor 4, slowly pull the biopsy needle back so that the temperature sensor probe is close to the inner wall of the abdominal cavity, observe the temperature display 8, and when the temperature is found to be different from the normal temperature When the difference is large, it means that the lesion has been found. At this time, the biopsy needle is pulled outward along the axial direction of the biopsy needle, so that the tissue of the lesion on the inner wall of the abdominal cavity enters the sampling cylinder 9, and then the sampling knife 10 is rotated, so that the sampling knife 10 moves along the axis of the biopsy needle. The mouth surface of the sampling cylinder 9 crosses the sampling cylinder to cut off the diseased tissue remaining in the sampling cylinder; then push the biopsy needle inward along the axis of the biopsy needle, turn the sampling knife 10 back, and place it in the circular concave In the groove 3, push the temperature sensor control rod 7, return the temperature sensor 4 to the groove 2, slowly extract the biopsy needle out of the patient's body, and finally take out the diseased tissue in the sampling cylinder 9, and finally achieve the purpose of sampling. By using the biopsy needle of the present invention, not only can the temperature sensor be used for accurate positioning and sampling, but also the sampling cylinder is specially set up. Compared with the traditional sampling method, the amount of tissue samples obtained is larger and more materials are obtained, which is convenient for obtaining better positive results and avoids the Injury to patients caused by less and repeated punctures.
作为对本实施例的进一步改进，所述温度感应装置和取样装置为多个且沿圆周方向均匀分布，以便于取得更多样品组织。As a further improvement to this embodiment, there are multiple temperature sensing devices and sampling devices that are evenly distributed along the circumferential direction, so as to obtain more sample tissues.
作为对本实施例的进一步改进，所述温度感应活检针的尾部还设置有控制杆固定盖12，用于固定温度感应器控制杆7和取样刀控制杆11。As a further improvement to this embodiment, the tail of the temperature sensing biopsy needle is also provided with a control rod fixing cover 12 for fixing the temperature sensor control rod 7 and the sampling knife control rod 11 .
作为对本实施例的进一步改进，所述活检针的针尖13以可沿针管轴向移动的方式内套于针管内，针管内沿轴向还设置有针尖控制杆14，针尖控制杆14与针尖13固定连接，控制杆固定盖12的针尖控制杆固定孔上设置有内螺纹，针尖控制杆上设置有与内螺纹相配合的外螺纹。As a further improvement to this embodiment, the needle point 13 of the biopsy needle is set inside the needle tube in a manner that can move along the needle tube axis, and a needle point control rod 14 is also arranged in the needle tube along the axial direction, and the needle point control rod 14 is connected with the needle point 13 Fixedly connected, the needle point control rod fixing hole of the control rod fixing cover 12 is provided with an internal thread, and the needle point control rod is provided with an external thread matched with the internal thread.
最后说明的是，以上实施例仅用以说明本发明的技术方案而非限制，尽管参照较佳实施例对本发明进行了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的宗旨和范围，其均应涵盖在本发明的权要求范围当中。Finally, it is noted that the above embodiments are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be carried out Modifications or equivalent replacements without departing from the spirit and scope of the technical solutions of the present invention shall be covered by the claims of the present invention.
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| CN104127174A (en) * | 2013-11-18 | 2014-11-05 | 成都科创佳思科技有限公司 | Multifunctional pulse diagnosis device for traditional Chinese medicine |
| CN105615928B (en) * | 2014-10-27 | 2019-01-15 | 中国人民解放军第二军医大学 | A kind of syringe needle |
| CN106691550A (en) * | 2016-11-23 | 2017-05-24 | 中国人民解放军第三军医大学第附属医院 | Breast tissue puncture biopsy needle |
| CN108272475B (en) * | 2018-01-26 | 2020-10-16 | 青岛大学附属医院 | Tumor specimen collecting device for surgical operation |
| CN110279436B (en) * | 2019-03-26 | 2023-12-29 | 江南大学 | Vaginal microecological specimen collector |
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| CN2228328Y (en) * | 1995-03-03 | 1996-06-05 | 中国人民武装警察部队河北省总队医院 | Pleura biopsy needle |
| US6066153A (en) * | 1999-03-31 | 2000-05-23 | Lev; Avigdor | Device and method for resecting body tissues |
| CN201312816Y (en) * | 2008-11-20 | 2009-09-23 | 王万学 | Novel dermatology scraper |
| CN201409940Y (en) * | 2009-06-06 | 2010-02-24 | 吕欣 | pleural biopsy sampler |
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| US7517321B2 (en) * | 2005-01-31 | 2009-04-14 | C. R. Bard, Inc. | Quick cycle biopsy system |
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| CN2228328Y (en) * | 1995-03-03 | 1996-06-05 | 中国人民武装警察部队河北省总队医院 | Pleura biopsy needle |
| US6066153A (en) * | 1999-03-31 | 2000-05-23 | Lev; Avigdor | Device and method for resecting body tissues |
| CN201312816Y (en) * | 2008-11-20 | 2009-09-23 | 王万学 | Novel dermatology scraper |
| CN201409940Y (en) * | 2009-06-06 | 2010-02-24 | 吕欣 | pleural biopsy sampler |
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