CN106215094A - A kind of relieving alcoholism and protecting the liver health product and preparation method thereof - Google Patents
A kind of relieving alcoholism and protecting the liver health product and preparation method thereof Download PDFInfo
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- CN106215094A CN106215094A CN201610613637.7A CN201610613637A CN106215094A CN 106215094 A CN106215094 A CN 106215094A CN 201610613637 A CN201610613637 A CN 201610613637A CN 106215094 A CN106215094 A CN 106215094A
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Abstract
The present invention relates to a kind of relieving alcoholism and protecting the liver health product and preparation method thereof, these relieving alcoholism and protecting the liver health product, formed by the extract of component A, B component and adjuvant are compounding: described component A is made up of the raw material of following weight portion: Herba Artemisiae Scopariae 4～8 parts, Rhizoma Polygoni Cuspidati 5～10 parts, Radix Curcumae 6～10 parts, Radix Angelicae Pubescentis 3～8 parts, Fructus Schisandrae Chinensis 7～11 parts, SHANZHIZI 6～12 parts, Flos puerariae lobatae 7～12 parts, papaw 3～8 parts, Fructus Lycii 7～15 parts and Radix Et Caulis Acanthopanacis Senticosi 1～5 parts；Described B component is made up of the raw material of following weight portion: L arabinose 10～15 parts and propolis powder 3～5 parts；The part by weight of the extract of described component A, B component and adjuvant is 1:1～2:1.5～3.The present invention has L arabinose and propolis powder with the extract of the component A raw material of certain part by weight ratio for activated feedstock is compounding, and these health product are not only notable in the effect of the liver protecting, decomposing alcohol and the aspect such as resisting fatigue, enhancing human body immunity and have preferable taste.
Description
Technical field
The present invention relates to a kind of relieving alcoholism and protecting the liver health product and preparation method thereof, belong to relieving alcoholism and protecting the liver field of health care food.
Background technology
Getting more and more along with various communications in the modern life, drink more and more, excessive drinking and alcoholic increase the most day by day
Many, badly influence the healthy of people and family, social stablizing.Although wine has preferable pharmacological action to human body,
But there is also toxicological effect, acute heavy drinking can cause Nausea and vomiting, hypomnesis, absent minded, finely transport
Kinetic force is impaired and emotional instability, if alcoholic liver sustainable development becomes serious, symptom of digestive tract can be obvious, has evil
The different symptoms such as the heart, vomits, loss of appetite, weak, becomes thin, hepatic region pain, severe patient is acute severe hepatitis or hepatic failure.Cause
This, the gentle alcoholic liver tool that solves of prevention is of great significance.
Summary of the invention
The technical problem to be solved is to provide a kind of relieving alcoholism and protecting the liver health product and preparation method thereof, overcomes existing
Relieving alcoholism and protecting the liver health product exist the not notable defect of effect alleviating alcoholic liver.
The technical scheme is that a kind of relieving alcoholism and protecting the liver health product, by the extraction of component A
The compounding composition of thing, B component and adjuvant: described component A is made up of the raw material of following weight portion: Herba Artemisiae Scopariae 4～8 parts, Rhizoma Polygoni Cuspidati 5～10
Part, Radix Curcumae 6～10 parts, Radix Angelicae Pubescentis 3～8 parts, Fructus Schisandrae Chinensis 7～11 parts, SHANZHIZI 6～12 parts, Flos puerariae lobatae 7～12 parts, papaw 3～8
Part, Fructus Lycii 7～15 parts and Radix Et Caulis Acanthopanacis Senticosi 1～5 parts；Described B component is made up of the raw material of following weight portion: L-arabinose 10～15
Part and propolis powder 3～5 parts；The part by weight of the extract of described component A, B component and adjuvant is 1:1～2:1.5～3.
The invention has the beneficial effects as follows: the present invention is former for activity with the extract of the component A raw material of certain part by weight ratio
Material is compounding L-arabinose and propolis powder, and these health product are not only exempted from the liver protecting, decomposing alcohol and resisting fatigue, enhancing body
The effect of the aspects such as epidemic disease is notable and has preferable taste.
On the basis of technique scheme, the present invention can also do following improvement.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, described adjuvant is by the raw material group of following weight portion
Become: starch 6～10 parts, mannitol 4～10 parts, micropowder silica gel 6～12 parts, magnesium stearate 5～10 parts and oligosaccharide 8～10 parts.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, described adjuvant is by the raw material group of following weight portion
Become: starch 8 parts, 8 parts of mannitol, micropowder silica gel 10 parts, magnesium stearate 6 parts and oligosaccharide 10 parts.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, described component A is by the raw material group of following weight portion
Become: Herba Artemisiae Scopariae 5 parts, Rhizoma Polygoni Cuspidati 7 parts, Radix Curcumae 8 parts, Radix Angelicae Pubescentis 6 parts, Fructus Schisandrae Chinensis 8 parts, SHANZHIZI 10 parts, Flos puerariae lobatae 10 parts, papaw 7 parts, Chinese holly
Qi 13 parts and Radix Et Caulis Acanthopanacis Senticosi 3 parts.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, described component A is by the raw material group of following weight portion
Become: Herba Artemisiae Scopariae 6 parts, Rhizoma Polygoni Cuspidati 7 parts, Radix Curcumae 8 parts, Radix Angelicae Pubescentis 7 parts, Fructus Schisandrae Chinensis 8 parts, SHANZHIZI 8 parts, Flos puerariae lobatae 9 parts, papaw 67 parts, Chinese holly
Qi 8 parts and Radix Et Caulis Acanthopanacis Senticosi 2 parts.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, described L-arabinose 12 parts and propolis powder 4
Part.
The present invention a kind of relieving alcoholism and protecting the liver health product as mentioned above, further, the extract of described component A, B component and adjuvant
Part by weight be 1:1.5:2.
The present invention also provides for the preparation method of a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) according to weight
Part ratio weighs each raw material, first will pulverize after 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp
Irradiate 30 minutes-60 minutes；Then respectively or raw material after mixing, is added at Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi
The 80-90 DEG C water of 3.5～5 times of weight portions of amount is extracted 1-2 hour, collects filtrate, and medicinal residues are adding and the water yield for the first time
Identical water extracts 1-2 hour in 80-90 DEG C water, collects filtrate, merges twice filtrate, and being evaporated to relative density is
1.02-1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule.
The preparation method of the present invention a kind of relieving alcoholism and protecting the liver health product described above, further, described Flos puerariae lobatae, SHANZHIZI, ten thousand
Longevity fruit and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 5～10%.
The preparation method of the present invention a kind of relieving alcoholism and protecting the liver health product described above, further, in step (2) obtained
Grain conventional method is prepared as granule or capsule, and described granule or capsule are distributed into the teabag of every bag of 5g.
L-arabinose can remove the low density lipoprotein, LDL in liver and blood, prevention fatty liver and hepatoprotective effect, resists
Aging, enhancing human body immunity power, reduces blood fat；Propolis is referred to as " purple gold ", and a large amount of medical practices and scientific research prove: propolis
Have and significantly control blood pressure, blood glucose；Reduce the excellent effect of blood fat suppression tumor.
Flos puerariae lobatae, Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, SHANZHIZI, papaw, Fructus Lycii and Radix Et Caulis Acanthopanacis Senticosi are compounding can be carried
The adaptation ability of high body environment to external world, anti-evil ability and rehabilitation ability.By QI invigorating, nourish blood, YIN nourishing, the method such as tonifying YANG are held up
Help healthy energy, to increase body constitution, improve resistance against diseases.
Flos puerariae lobatae: for the dry flower of legume pueraria lobata.The books such as Shennong's Herbal, Compendium of Material Medica all record
" relieving acute alcoholism and recuperating the spleen " and effect.It is the most representational natural plants that relieves the effect of alcohol in traditional medicine, there is good liver protection effect, improve
The pathobolism that ethanol causes.
Herba Artemisiae Scopariae: Herba Artemisiae Scopariae has significant hepatoprotective effect, to first, hepatitis B, icterohepatitis, has significant curative effect.Favorably
Gallbladder, promotes bile secretion, increases the effect that in bile, cholic acid and bilirubin are discharged. heart coronary flow can be increased, improve micro-
Circulation, and has blood pressure lowering, blood fat reducing, anticoagulation, and diuresis is antipyretic relievings asthma, drive away ascarid and suppress multiple pathogenic dermatophytes with
The effect of antibacterial.
Rhizoma Polygoni Cuspidati: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.
Radix Curcumae: circulation of qi promoting, resolving depression；Let out blood, removing blood stasis with potent drugs.
Radix Angelicae Pubescentis: expelling wind and dampness；Dispersing cold for relieving pain.For anemofrigid-damp arthralgia；Lumbocrural pain；Few the moon volt wind headache, toothache of having a headache.
Fructus Schisandrae Chinensis: Fructus Schisandrae Chinensis dietary function: Fructus Schisandrae Chinensis sour in the mouth, warm in nature；Return lung, the heart, kidney channel；Hold back fall have convergence astringent or styptic treatment for spontaneous sweating,
Supplementing QI for promoting the production of body fluid, effect that kidney calming is calmed the nerves.
SHANZHIZI: heat clearing away, pathogenic fire purging, removing heat from blood.
Papaw: have effect of heat clearing away, diuresis, alcoholic intoxication.
Fructus Lycii: Fructus Lycii: nourishing the liver, nourishing kidney, lung moistening.Folium Lycii: qi-restoratives benefit essence, clearing away heat to improve acuity of vision.
Radix Et Caulis Acanthopanacis Senticosi: anemofrigid-damp arthralgia；Lumbocrural pain；Muscles and bones flaccidity is soft；It is slow in action；Body weakness with emaciation is weak；Traumatic injury；Fracture；Water
Swollen；Tinea pedis；Uncontrolled urination is itched.
Oligosaccharide: be a kind of efficiently bifidus factor, be also a kind of dietary fiber, be to be bonded by glucosides by 2-10 monosaccharide
Connecing the oligosaccharide forming straight or branched, functional oligose has many excellent characteristic, physiologically active and health care, energy
The liver protecting cell, reduces the oil droplet in liver cell, protects again gastric mucosa simultaneously, the most helpful to liver and stomach.
Detailed description of the invention
Principle and feature to the present invention are described with the following Examples, and example is served only for explaining the present invention,
It is not intended to limit the scope of the present invention.
Embodiment 1
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Divide and be made up of following raw material: Herba Artemisiae Scopariae 4g, Rhizoma Polygoni Cuspidati 5g, Radix Curcumae 6g, Radix Angelicae Pubescentis 3g, Fructus Schisandrae Chinensis 7g, SHANZHIZI 6g, Flos puerariae lobatae 7g, Wan Shou
Really 3g, Fructus Lycii 7g and Radix Et Caulis Acanthopanacis Senticosi 1g；Described B component is made up of following raw material: L-arabinose 10g and propolis powder 3g；Described
Adjuvant is made up of following raw material: starch 6g, mannitol 4g, micropowder silica gel 6g, magnesium stearate 5g and oligosaccharide 8g；Described A group
The part by weight of the extract, B component and the adjuvant that divide is 1:1:1.5.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, irradiated 30 minutes points after first pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp
Clock, described Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 5%；By mattress
Old, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi are respectively or 80 DEG C water of add material quantity after mixing 3.5 times extract 1
Hour, collect filtrate, medicinal residues are adding the water identical with the water yield for the first time in 80-90 DEG C water extraction 1 hour, collection filter
Liquid, merges twice filtrate, and being evaporated to relative density is 1.02, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 2
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Point be made up of following raw material: Herba Artemisiae Scopariae 8g, Rhizoma Polygoni Cuspidati 10g, Radix Curcumae 10g, Radix Angelicae Pubescentis 8g, Fructus Schisandrae Chinensis 11g, SHANZHIZI 12g, Flos puerariae lobatae 12g,
Papaw 8g, Fructus Lycii 15g and Radix Et Caulis Acanthopanacis Senticosi 5g；Described B component is made up of following raw material: L-arabinose 15g and propolis powder 5g；
Described adjuvant is made up of following raw material: starch 10g, mannitol 10g, micropowder silica gel 12g, magnesium stearate 10g and oligosaccharide
10g；The part by weight of the extract of described component A, B component and adjuvant is 1:2:3.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 60 minutes after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp；Pueraria lobota
Flower, SHANZHIZI, papaw and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 10%；By Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati,
Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi respectively or add 90 DEG C water of 5 times of material quantity and extract 2 hours after mixing, collect
Filtrate, medicinal residues extract 2 hours in 90 DEG C water at the water that addition is identical with the water yield for the first time, collect filtrate, merge twice filter
Liquid, being evaporated to relative density is 1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 3
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Point be made up of following raw material: Herba Artemisiae Scopariae 5g, Rhizoma Polygoni Cuspidati 7g, Radix Curcumae 8g, Radix Angelicae Pubescentis 6g, Fructus Schisandrae Chinensis 8g, SHANZHIZI 10g, Flos puerariae lobatae 10g, ten thousand
Longevity fruit 7g, Fructus Lycii 13g and Radix Et Caulis Acanthopanacis Senticosi 3g；Described B component is made up of following raw material: L-arabinose 15g and propolis powder 5g；Institute
State adjuvant to be made up of following raw material: starch 10g, mannitol 6g, micropowder silica gel 10g, magnesium stearate 8g and oligosaccharide 9g；Described
The part by weight of the extract of component A, B component and adjuvant is 1:1.2:1.8.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 50 minutes, Pueraria lobota after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp
Flower, SHANZHIZI, papaw and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 8%；By Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, strongly fragrant
Gold, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi respectively or add the 80-90 DEG C water of 4 times of material quantity and extract 2 hours after mixing, collect
Filtrate, medicinal residues extract 2 hours in 80-90 DEG C water at the water that addition is identical with the water yield for the first time, collect filtrate, merge twice
Filtrate, being evaporated to relative density is 1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 4
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Point be made up of following raw material: Herba Artemisiae Scopariae 5g, Rhizoma Polygoni Cuspidati 7g, Radix Curcumae 8g, Radix Angelicae Pubescentis 6g, Fructus Schisandrae Chinensis 8g, SHANZHIZI 10g, Flos puerariae lobatae 10g, ten thousand
Longevity fruit 7g, Fructus Lycii 13g and Radix Et Caulis Acanthopanacis Senticosi 3g；Described B component is made up of following raw material: L-arabinose 12g and propolis powder 4g；Institute
State adjuvant to be made up of following raw material: starch 6～10g, mannitol 4～10g, micropowder silica gel 6～12g, magnesium stearate 5～10g
With oligosaccharide 8～10g；The part by weight of the extract of described component A, B component and adjuvant is 1:1.5:2.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 60 minutes, Pueraria lobota after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp
Flower, SHANZHIZI, papaw and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 9%；Then Herba Artemisiae Scopariae, tiger
Cane, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi respectively or add 90 DEG C water of 5 times of material quantity and extract 1-2 hour after mixing,
Collecting filtrate, medicinal residues extract 1.5 hours in 90 DEG C water at the water that addition is identical with the water yield for the first time, collect filtrate, merge
Twice filtrate, being evaporated to relative density is 1.02-1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 5
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Divide and be made up of following raw material: Herba Artemisiae Scopariae 6g, Rhizoma Polygoni Cuspidati 7g, Radix Curcumae 8g, Radix Angelicae Pubescentis 7g, Fructus Schisandrae Chinensis 8g, SHANZHIZI 8g, Flos puerariae lobatae 9g, Wan Shou
Really 67g, Fructus Lycii 8g and Radix Et Caulis Acanthopanacis Senticosi 2g；Described B component is made up of following raw material: L-arabinose 10g and propolis powder 3g；Described
Adjuvant is made up of following raw material: starch 6g, mannitol 8g, micropowder silica gel 7g, magnesium stearate 9g and oligosaccharide 10g；Described A group
The part by weight of the extract, B component and the adjuvant that divide is 1:1.8:1.5.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 60 minutes after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp；So
After respectively or add 80 DEG C water of 5 times of material quantity after mixing at Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi
Extracting 2 hours, collect filtrate, medicinal residues are adding the water identical with the water yield for the first time in 90 DEG C water extraction 1 hour, collection filter
Liquid, merges twice filtrate, and being evaporated to relative density is 1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 6
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Divide and be made up of following raw material: Herba Artemisiae Scopariae 6g, Rhizoma Polygoni Cuspidati 7g, Radix Curcumae 8g, Radix Angelicae Pubescentis 7g, Fructus Schisandrae Chinensis 8g, SHANZHIZI 8g, Flos puerariae lobatae 9g, Wan Shou
Really 67g, Fructus Lycii 8g and Radix Et Caulis Acanthopanacis Senticosi 2g；Described B component is formed described L-arabinose 12g and propolis powder 4g by following raw material；
Described adjuvant is made up of following raw material: starch 8g, mannitol 8g, micropowder silica gel 10g, magnesium stearate 6g and oligosaccharide 7g；Institute
The part by weight stating the extract of component A, B component and adjuvant is 1:1.5:2.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 60 minutes after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp；So
After respectively or add 80 degrees Celsius of 3.5 times of material quantity after mixing at Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi
Water extraction 1 hour, collects filtrate, and medicinal residues are adding the water identical with the water yield for the first time in 80 DEG C water extraction 1 hour, collection
Filtrate, merges twice filtrate, and being evaporated to relative density is 1.02, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
Embodiment 7
One relieving alcoholism and protecting the liver health product of the present invention, are formed by the extract of component A, B component and adjuvant are compounding: described A group
Point be made up of following raw material: Herba Artemisiae Scopariae 5g, Rhizoma Polygoni Cuspidati 6g, Radix Curcumae 7g, Radix Angelicae Pubescentis 6g, Fructus Schisandrae Chinensis 10g, SHANZHIZI 11g, Flos puerariae lobatae 8g, ten thousand
Longevity fruit 5g, Fructus Lycii 10g and Radix Et Caulis Acanthopanacis Senticosi 4g；Described B component is made up of following raw material: L-arabinose 12g and propolis powder 4g；Institute
State adjuvant to be made up of following raw material: starch 8g, mannitol 8g, micropowder silica gel 10g, magnesium stearate 7g and oligosaccharide 9g；Described A
The part by weight of the extract of component, B component and adjuvant is 1:1.8:1.5.
The preparation method of above-mentioned a kind of relieving alcoholism and protecting the liver health product, comprises the following steps: step 1) proportionally weigh each former
Material, first irradiates 60 minutes after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry under uviol lamp；So
After respectively or add 90 DEG C water of 4 times of material quantity after mixing at Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi
Extracting 2 hours, collect filtrate, medicinal residues extract 1.5 hours in 80-90 DEG C water at the water that addition is identical with the water yield for the first time,
Collecting filtrate, merge twice filtrate, being evaporated to relative density is 1.05, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution
Rear addition L-arabinose, propolis powder and adjuvant, sieve and make granule；Obtained granule conventional method is prepared as granule
Or capsule, described granule or capsule are distributed into the teabag of every bag of 5g.
The alcohol-neutralize healthy product of the present invention is investigated on mice relieving alcoholic intoxication and the impact of sobering-up functions below by zoopery.
Experimental technique:
The teabag of every bag of 5g of Example 1 to 7 soaks and adds 200mL boiling water immersion 10 minutes；Take mice 80
(NIH), male and female half and half, be divided into 8 groups at random, often group 10,1 group for gavaging merely ethanol group, 2 groups to 8 groups for the most successively
Gavage embodiment 1 to embodiment 7 alcohol-neutralize healthy product with wine group；
Concrete operations are: 1 group of gavage 0.5ml ethanol, 2 groups to 8 groups gavage the most successively before gavage ethanol embodiment 1 to
The alcohol-neutralize healthy product 100mL of embodiment 7, gavage ethanol subsequently, after gavage ethanol when immediate record righting reflex loss and recovery
Between.Calculating Sleep latency respectively and enter the length of one's sleep, result is as shown in table 1 below.
Table 1: Sleep latency and the experiment length of one's sleep
From upper table data: the health product of the present invention have the prolongation mice drunk time and shorten the trend of relieving alcoholic intoxication time,
And its impact more significant (P ＜ 0.05), therefore the present invention has good antialcoholism function.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (10)
1. relieving alcoholism and protecting the liver health product, it is characterised in that formed by the extract of component A, B component and adjuvant are compounding: described A
Component is made up of the raw material of following weight portion: Herba Artemisiae Scopariae 4～8 parts, Rhizoma Polygoni Cuspidati 5～10 parts, Radix Curcumae 6～10 parts, Radix Angelicae Pubescentis 3～8 parts, the five tastes
Son 7～11 parts, SHANZHIZI 6～12 parts, Flos puerariae lobatae 7～12 parts, papaw 3～8 parts, Fructus Lycii 7～15 parts and Radix Et Caulis Acanthopanacis Senticosi 1～5 parts；Institute
State B component to be made up of the raw material of following weight portion: L-arabinose 10～15 parts and propolis powder 3～5 parts；Carrying of described component A
The part by weight taking thing, B component and adjuvant is 1:1～2:1.5～3.
A kind of relieving alcoholism and protecting the liver health product, it is characterised in that described adjuvant is former by following weight portion
Material composition: starch 6～10 parts, mannitol 4～10 parts, micropowder silica gel 6～12 parts, magnesium stearate 5～10 parts and oligosaccharide 8～10
Part.
A kind of relieving alcoholism and protecting the liver health product, it is characterised in that described adjuvant is former by following weight portion
Material composition: starch 8 parts, 8 parts of mannitol, micropowder silica gel 10 parts, magnesium stearate 6 parts and oligosaccharide 10 parts.
4. according to relieving alcoholism and protecting the liver health product a kind of described in any one of claims 1 to 3, it is characterised in that described component A is by following
The raw material composition of weight portion: Herba Artemisiae Scopariae 5 parts, Rhizoma Polygoni Cuspidati 7 parts, Radix Curcumae 8 parts, Radix Angelicae Pubescentis 6 parts, Fructus Schisandrae Chinensis 8 parts, SHANZHIZI 10 parts, Flos puerariae lobatae 10
Part, papaw 7 parts, Fructus Lycii 13 parts and Radix Et Caulis Acanthopanacis Senticosi 3 parts.
5. according to relieving alcoholism and protecting the liver health product a kind of described in any one of claims 1 to 3, it is characterised in that described component A is by following
Weight portion raw material composition: Herba Artemisiae Scopariae 6 parts, Rhizoma Polygoni Cuspidati 7 parts, Radix Curcumae 8 parts, Radix Angelicae Pubescentis 7 parts, Fructus Schisandrae Chinensis 8 parts, SHANZHIZI 8 parts, Flos puerariae lobatae 9 parts,
Papaw 67 parts, Fructus Lycii 8 parts and Radix Et Caulis Acanthopanacis Senticosi 2 parts.
6. according to relieving alcoholism and protecting the liver health product a kind of described in any one of claims 1 to 3, it is characterised in that described L-arabinose
12 parts and propolis powder 4 parts.
7. according to relieving alcoholism and protecting the liver health product a kind of described in any one of claims 1 to 3, it is characterised in that the extraction of described component A
The part by weight of thing, B component and adjuvant is 1:1.5:2.
8. the preparation method of relieving alcoholism and protecting the liver health product, it is characterised in that comprise the following steps: step 1) according to weight part ratio
Example weighs each raw material, first irradiates under uviol lamp after pulverizing 40 mesh sieves after Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii fried dry
30 minutes-60 minutes；Then respectively or material quantity after mixing, is added at Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Curcumae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Radix Et Caulis Acanthopanacis Senticosi
The 80-90 DEG C water of 3.5～5 times of weight portions is extracted 1-2 hour, collects filtrate, and medicinal residues are identical with the water yield for the first time in addition
Water 80-90 DEG C water extract 1-2 hour, collect filtrate, merge twice filtrate, being evaporated to relative density is
1.02-1.12, it is thus achieved that concentrated solution；
Step 2) by step 1) in the mixed-powder of Flos puerariae lobatae, SHANZHIZI, papaw and Fructus Lycii mix homogeneously with concentrated solution after add
Enter L-arabinose, propolis powder and adjuvant and make granule.
The preparation method of a kind of relieving alcoholism and protecting the liver health product, it is characterised in that described Flos puerariae lobatae, Fructus Gardeniae
Son, papaw and Fructus Lycii parch temperature are 40～50 DEG C, are fried to feed moisture content 5～10%.
The preparation method of a kind of relieving alcoholism and protecting the liver health product, it is characterised in that made in step (2)
The granule conventional method obtained is prepared as granule or capsule, and described granule or capsule are distributed into the bag bubble of every bag of 5g
Tea.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156724A (en) * | 2017-06-07 | 2017-09-15 | 于国军 | A kind of haw jelly with sober-up function and preparation method thereof |
| CN109122856A (en) * | 2018-07-05 | 2019-01-04 | 乙丙丁健康产业（深圳）有限公司 | A kind of liver-protecting sober-up Chinese medicine composition |
| US20220408758A1 (en) * | 2019-09-12 | 2022-12-29 | Toyo Shinyaku Co., Ltd. | Dried kudzu flower powder and food product comprising dried kudzu flower powder |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101797279A (en) * | 2009-11-26 | 2010-08-11 | 济南圣泉唐和唐生物科技有限公司 | Health care product with dealcoholic function |
| CN103285252A (en) * | 2012-12-27 | 2013-09-11 | 福建永生活力生物工程有限公司 | Oral liquid for alleviating hangover and protecting liver, and preparation method thereof |
| CN104982817A (en) * | 2015-06-29 | 2015-10-21 | 安徽省怀宁县顶雪食品有限公司 | Sobering liver-nourishing tribute noodles and making method thereof |
| CN105311204A (en) * | 2014-05-27 | 2016-02-10 | 周瑞 | Liver protection health product |
-
2016
- 2016-07-29 CN CN201610613637.7A patent/CN106215094A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101797279A (en) * | 2009-11-26 | 2010-08-11 | 济南圣泉唐和唐生物科技有限公司 | Health care product with dealcoholic function |
| CN103285252A (en) * | 2012-12-27 | 2013-09-11 | 福建永生活力生物工程有限公司 | Oral liquid for alleviating hangover and protecting liver, and preparation method thereof |
| CN105311204A (en) * | 2014-05-27 | 2016-02-10 | 周瑞 | Liver protection health product |
| CN104982817A (en) * | 2015-06-29 | 2015-10-21 | 安徽省怀宁县顶雪食品有限公司 | Sobering liver-nourishing tribute noodles and making method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156724A (en) * | 2017-06-07 | 2017-09-15 | 于国军 | A kind of haw jelly with sober-up function and preparation method thereof |
| CN109122856A (en) * | 2018-07-05 | 2019-01-04 | 乙丙丁健康产业（深圳）有限公司 | A kind of liver-protecting sober-up Chinese medicine composition |
| US20220408758A1 (en) * | 2019-09-12 | 2022-12-29 | Toyo Shinyaku Co., Ltd. | Dried kudzu flower powder and food product comprising dried kudzu flower powder |
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Application publication date: 20161214 |