CN103623280A - Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases - Google Patents
Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation disclosed by the invention comprises the raw materials of active components: semen sesami nigrum, Chinese yam, kudzuvine root, amaranthus dubius, gingko, cortex eucommiae, polygonum multiflorum, Chinese maple leaves, salvia miltiorrhiza, carrot, mushroom, agarics, urtica, hawthorn, gracilaria lemaneiformis and asparagus. The traditional Chinese medicine preparation has the efficacies of promoting blood circulation and removing blood stasis, replenishing qi and nourishing blood, nourishing yin and cooling blood as well as clearing heat and detoxicating, has remarkable curative effects on alleviation of cardiovascular syndromes such as limb hemiplegia, chest distress and cardiodynia, dizziness, palpitation, headache and the like caused by hyperlipidemia, hypertension, coronary heart diseases and cerebral infarction and has the advantages of simplicity in preparation process, low cost and no toxic or side effects, and is worth of wide clinical popularization and application.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease.
Background technology
Cardiovascular and cerebrovascular disease is exactly cardiovascular and cerebrovascular disease general designation.Cardiovascular and cerebrovascular disease is a kind of serious threat mankind, the commonly encountered diseases of 50 years old above middle-aged and elderly people health particularly, even if apply most advanced, perfect at present treatment means, still can there is more than 50% cerebrovascular accident survivor life not take care of oneself completely, cardiovascular and cerebrovascular disease has become the No.1 killer that mankind's Death causes is the highest, is also " the noiseless demon " of health of people.
Cardiovascular and cerebrovascular disease has that sickness rate is high, disability rate is high, mortality rate is high, relapse rate is high and the feature of " four is high by more than " that complication is many.
At present, China's Patients with Cardiovascular/Cerebrovascular Diseases has surpassed 2.7Yi Ren， China and has died from every year 51% of the annual total Death causes of cardiovascular and cerebrovascular disease Jin300 Wan Ren，Zhan China, and the patient 75% who survives disability in various degree, 40% is heavy residual.China's patient with cerebral apoplexy leave hospital after the relapse rate of First Year be the relapse rate of 30%, the five year up to 59%, and secondary prevention do preferably the U.S. be only 10%.
Treatment for cardiovascular and cerebrovascular vessel does not at present have specific medicine, particularly in therapeutic process, conventionally use the medicine of some chemicals, the side effect of these medicines is larger, in the process of using these chemicals medicines, to other organs of user, can bring very large infringement, and after drug withdrawal, the interior state of an illness of short time will recur, therefore, research and develop the medicine of new treatment cardiovascular and cerebrovascular disease, the person's that is always medical research focus.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease; Chinese medicine preparation of the present invention has the effect of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, phencyclidine, heat-clearing and toxic substances removing, to alleviating the symptom of the cardiovascular and cerebrovascular vessel such as the hemiplegia of limb that caused by hyperlipidemia, hypertension, coronary heart disease, cerebral infarction, pained, dizzy, cardiopalmus uncomfortable in chest, headache, there is significant curative effect, and there is the advantages such as preparation technology is simple, cost is lower, without any side effects, be worth wide popularization and application clinically.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for cardiovascular and cerebrovascular disease, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of cardiovascular and cerebrovascular disease, comprise following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that under 60 ℃ of environment, relative density is 1.10～1.16, standby;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice standby;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and is condensed into the thick paste that under 70 ℃ of environment, relative density is 1.20～1.25, standby;
(5) above-mentioned steps (1)～(4) prepared fine powder, thick paste and juice are mixed, utilize modern advanced pharmacy science and technology, make tablet, obtain the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Semen Sesami Nigrum: sweet in the mouth, property is flat; Enter liver, kidney, lung, spleen channel.The improving eyesight of enriching blood, the intestine moistening of dispeling the wind, the lactogenesis that promotes the production of body fluid, the liver benefiting hair care, keeps fit body, defying age.Can be used for treating physical weakness, dizziness and tinnitus, hypertension, hyperlipidemia, cough, physical weakness, early whitening of hair, anemia is sallow, deficiency of body fluid, constipation due to dry stool, breast is few, the diseases such as hematuria.< < Compendium of Materia Medica > > carries: " can be used for that Liver and kidney two void, muscles and bones are strong, extremity are aching and limp unable etc.”
Rhizoma Dioscoreae: sweet in the mouth, property is flat; Enter spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, and leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.The positive > > of < < book on Chinese herbal medicine carries: " Rhizoma Dioscoreae, energy spleen invigorating tonify deficiency, grows essence and reinforce the kidney, and controls weakness, treats five kinds of strain and seven kinds of impairment.The light property of its gas is slow, non-may be full-time, therefore spleen reinforcing lung must mainly be joined, art, the kidney invigorating water must monarch Zhu,, puckery foul leukorrhea must be broken therefore with grinding, solid spermatorrhea battle Herba cuscutae helps mutually, and all balls consolidate pill, also should smash end for paste, nature and flavor are weak in a word, but can firmly help and make.”
Radix Puerariae: sweet in the mouth, pungent, cool in nature; Enter spleen, stomach warp.Induce sweat and bring down a fever, the rash of promoting the production of body fluid, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels.< < Compendium of Materia Medica > > carries: " Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling." modern medicine study shows, the isoflavonoid puerarin in Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Amaranthus mangostanus L.: taste is micro-sweet, cool in nature; Enter lung, large intestine channel.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, dysentery relieving.Cure mainly dysentery, constipation and anuresis, conjunctival congestion pharyngalgia, the diseases such as epistaxis.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > > carries: " control sphincter disturbance, change worm, cold removing heat, energy promoting blood circulation, removing blood stasis blood.”
Semen Ginkgo: sweet in the mouth, hardship, puckery, property is flat; Enter lung, kidney channel.The gas of astringing the lung, relieving asthma and cough, leukorrhagia stopping is turbid, urine reducing, disinfection.Cure mainly asthma, phlegmatic cough, nocturnal emission, leucorrhea, nebulousurine, infantile diarrhea, malnutrition due to parasitic infestation, hemorrhoidal hamorrhage dysentery, gonorrhea, frequent micturition, and the disease such as scabies, dermatitis rhus, white tumor wind.< < herbal classic meets source > > to carry: " in carry the function that Semen Ginkgo has the expectorant of falling, detoxicating, parasite killing, can treat the diseases such as skin ulcer scabies cellulitis tumor, acute mastitis are festered, tooth worm dental caries, infantile diarrhea, leucorrhea with red and white discharge, chronic stranguria with turbid discharge, the seminal emission enuresis." modern medicine study confirmation, Semen Ginkgo has certain effect to treating the diseases such as hypertension and coronary heart diseases and angina pectoris, cerebral vasospasm, hypercholesterolemia.
The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening.Cure mainly spinal column ache, rheumatic arthralgia.According to < < Essential Recipes for Emergent Use Worth A Thousand Gold > >, carry: " function wind-damp dispelling, stopping numbness pain, liver and kidney tonifying; fill blood, the damp of having a cold, chills and pain of the waist and kness; podomere joint stuffiness, or benumb meciless, fear of cold happiness temperature." modern medicine study confirmation, the Cortex Eucommiae has sedation to nerve centre, can strengthen the immunologic function of cell, promotes cortisol secretion and cAMP in plasma and cGMP metabolism.
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver, kidney channel.Enrich and benefit essence and blood, removing toxic substances preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.Cure mainly blood deficiency anemia, Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, hemorrhoid.< < book on Chinese herbal medicine is stated > > and is carried: " control apoplexy, headache, migratory arthralgia, the arthroncus of knee, epilepsy syndrome, jaundice.”
Folium Evodiae trichotomae: acrid in the mouth, hardship, warm in nature; Attach to the lung and stomach meridians.Expelling wind and removing dampness, dispersing cold for relieving pain.Cure mainly your disease after poliomyelitis, rheumatic arthritis, eczema, urticaria, skin infection, headche due to wind-cold.< < Simao, Yunnan Chinese herbal medicine selects > > to carry: " control poliomyelitis sequela, rheumatic arthritis, urticaria, eczema, skin skin ulcer is itched.”
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature; Enter the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, evacuation of pus granulation promoting.For menoxenia, blood stasis is had a pain, amenorrhea, lump in the abdomen, coronary heart disease, angina pectoris, ectopic pregnancy, vexed interior-heat, carbuncle sore tumefacting virus etc.< < Japan hanako materia medica > > carries: " sedate of reposing, tonneau GUAN-pulse.Control cold and hot labor, arthralgia, extremity are unsuccessful, evacuation of pus pain relieving, granulation promoting is put on flesh, and broken stagnated blood, mends new hemopoietic, peaceful tire, the stillborn fetus that falls, under hemostasis metrorrhagia and leukorrhagia, adjusts married woman's passages through which vital energy circulates irregular, and blood evil thought is tired, malignant boil scabies, the wart toxic swelling of go to live in the household of one's in-laws on getting married, erysipelas, has a headache, acute conjunctivitis, hot temperature is mad vexed.”
Radix Dauci Sativae: sweet in the mouth, pungent, warm in nature, nontoxic.Strengthening the spleen to promote digestion, tonifying liver improving eyesight, heat-clearing and toxic substances removing, rash, sending down the abnormal ascending QI cough-relieving.For infantile malnutrition, measles, nyctalopia, constipation, hypertension, gastrointestinal upset, chronic dysentery, full stifling is swollen etc.< < day carries with herbal > >: " the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, loose stomach is possessed stagnant.”
Lentinus Edodes: sweet in the mouth, property is flat, nontoxic.Blood pressure lowering, blood fat reducing, cholesterol reducing.Cure mainly QI invigorating not hungry, control wind removing blood stasis, the deficiency of vital energy is dizzy, anemia, leukopenia, self-resistance declines and elderly and infirm should eat, hyperlipemia, hypertension, arteriosclerosis, diabetes, overweight people should eat, and after cancer patient and cancer patient's radiotherapy, chemotherapy, should eat, acute, chronic hepatitis, fatty liver, cholelithiasis, constipation person.
Auricularia: sweet in the mouth, property is flat, slightly poisonous.Modern medicine study confirmation, Auricularia is applicable to cardiovascular and cerebrovascular disease, calculosis edible for patients, and the personage, miner, metallurgical workman, weaving work, the hairdresser that are particularly suitable for iron deficiency are edible.
Herba Urticae Cannabinae: bitter in the mouth, pungent, warm in nature, poisonous.Dispelling wind and removing obstruction in the collateral, suppressing the hyperactive liver arresting convulsion, removing food stagnancy relieving constipation, removing toxic substances.Cure mainly rheumatic arthralgia, puerperal convulsion, infantile convulsion, poliomyelitis sequela, hypertension, dyspepsia, constipation, urticaria, traumatic injury, worm venom.The discriminating of < < Heilungkiang Main Wild Medicinal plant and Chinese herbal medicine novel formulation > > carry: " control poliomyelitis, rheumatism, colic.”
Fructus Crataegi: sweet in the mouth, acid, slightly warm in nature.Removing food stagnancy, clots absorbing, changes stagnant.< < day carries with herbal > >: " relieving dyspepsia is long-pending, row stagnation of QI, the wide diaphragm of stomach invigorating, the blood mass at the hypochondrium that disappears piece." modern medicine study confirms, Fructus Crataegi has blood vessel dilating, increases coronary flow, improves heart vigor, stimulating central nervous system system, reduce blood pressure and cholesterol, vessel softening and diuresis and sedation.
Thallus Gracilariae: sweet in the mouth, cold in nature; Return spleen channel.Hard masses softening and resolving, heat-clearing and toxic substances removing, dampness removing is aid digestion.Modern medicine study confirms, Thallus Gracilariae lung heat clearing relieving constipation, and skin care weight reducing, can blood pressure lowering, and blood fat reducing, adjusts physical function, enhancing immunity.
Germinatus Phragmitis: sweet in the mouth, hardship, cool in nature.Lung moistening antitussive, parasite killing eliminates the phlegm.Cure mainly heart disease, hypertension, tachycardias, fatigue, edema, cystitis, dysuria.Modern medicine study confirms, it is edible that Germinatus Phragmitis is applicable to hypertension, hyperlipemia, cancer, arteriosclerotic, be also simultaneously have a delicate constitution, insufficiency of vital energy and blood, malnutrition, anemia, obesity and habitual constipation person and hepatic insufficiency, oedema due to nephritis, lithangiuria person's first-selection.
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has the effect of blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, phencyclidine, heat-clearing and toxic substances removing, to alleviating the symptom of the cardiovascular and cerebrovascular vessel such as the hemiplegia of limb that caused by hyperlipidemia, hypertension, coronary heart disease, cerebral infarction, pained, dizzy, cardiopalmus uncomfortable in chest, headache, there is significant curative effect, and there is the advantages such as preparation technology is simple, cost is lower, without any side effects, be worth wide popularization and application clinically.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that under 60 ℃ of environment, relative density is 1.10～1.16, standby;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice standby;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and is condensed into the thick paste that under 70 ℃ of environment, relative density is 1.20～1.25, standby;
(5) above-mentioned steps (1)～(4) prepared fine powder, thick paste and juice are mixed, utilize modern advanced pharmacy science and technology, make tablet, obtain the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
Chinese medicine preparation as treatment cardiovascular and cerebrovascular disease, Patients with Cardiovascular/Cerebrovascular Diseases 200 examples that selection is made a definite diagnosis are carried out clinical observation, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 54 examples at random, women's 46 examples, 41～76 years old age, 55.8 years old mean age, the shortest person of the course of disease 2 months, elder 5 years, average 3.1 years.Matched group 100 examples, male's 53 examples wherein, women's 47 examples, 43～78 years old age, 43.5 years old mean age, the shortest person of the course of disease 3 months, elder 4 years, average 2.7 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Matched group is taken nitroglycerin, sublingual administration a slice nitroglycerin, as ineffective, every 5 minutes again containing changing a slice, can continuous application three times, be generally no more than three times; Within 9 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3～4 courses for the treatment of, and the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction all disappear, electrocardiogram shows that ischemic state recovery is normal.
(2) effective: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction alleviate or attack times reduces, electrocardiogram shows that myocardial ischemia improves
(3) effective: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction disappear substantially, electrocardiogram demonstration ischemic state recovers normal substantially.
(4) invalid: the disease symptomses such as hyperlipidemia, hypertension, coronary heart disease, cerebral infarction have no improvement.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 43 examples, effective 32 examples, effective 22 examples, invalid 3 examples, cure rate 43%, total effective rate 97%.
In matched group, cure 13 examples, effective 19 examples, effective 11 examples, invalid 57 examples, cure rate 13%, total effective rate 43%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, fourth, female, 48 years old, ShenZhen,GuangDong people.Patient suffers from cerebrovascular for many years, removes examination in hospital, is diagnosed as cardiovascular and cerebrovascular disease, uses multiple Drug therapy, has no sign of improvement.To our hospital afterwards, take Chinese medicine preparation of the present invention, fully recover after taking 1 course for the treatment of.
2, Feng, man, 55 years old, people from Yantai, Shandong.Patient suffers from hypertension and headache, uses multiple Drug therapy, poor effect.To our hospital, take Chinese medicine preparation of the present invention, to take after 1 course for the treatment of, symptom disappears substantially, takes after the 2nd course for the treatment of, and symptom all disappears.
3, permitted certain, man, 68 years old, people from Nanjing.Patient suffers from hyperlipidemia, hypertension for many years, removes hospital admission, is diagnosed as cardiovascular and cerebrovascular disease.Take Chinese medicine preparation of the present invention, every day 2 times, each 1 time sooner or later, each 2, to take after 1 course for the treatment of, symptom makes moderate progress, and takes transference cure after 2 courses for the treatment of, follows up a case by regular visits to, so far recurrence.
4, Luo, female, 72 years old, Shandong Dongying people.Patient suffers from cardiovascular and cerebrovascular disease, and blood pressure, blood fat continue to raise, and use many Drug therapys, lose improvement.To our hospital afterwards, take Chinese medicine preparation of the present invention, to take after 1 course for the treatment of, symptom disappears substantially, continues to take after 1 course for the treatment of, and above symptom disappears completely, follows up a case by regular visits to, so far not recurrence.
Claims (5)
1. a Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
45～80 parts of 50～80 parts of Amaranthus mangostanus L.s of 50～85 parts of Radix Puerariaes of 60～85 portions of Rhizoma Dioscoreaes of Semen Sesami Nigrum
35～70 parts of 40～70 parts of Folium Evodiae trichotomae of 40～75 parts of Radix Polygoni Multiflori of 40～80 parts of Cortexs Eucommiae of Semen Ginkgo
25～55 parts, 30～55 portions of Auricularias of 30～60 parts of Lentinus Edodess of 35～65 portions of Radix Dauci Sativaes of Radix Salviae Miltiorrhizae
15～40 parts of 15～45 portions of Germinatus Phragmitiss of 20～45 portions of Thallus Gracilariaes of 20～50 portions of Fructus Crataegis of Herba Urticae Cannabinae.
2. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
50～75 parts of 55～75 parts of Amaranthus mangostanus L.s of 55～80 parts of Radix Puerariaes of 65～80 portions of Rhizoma Dioscoreaes of Semen Sesami Nigrum
40～65 parts of 45～65 parts of Folium Evodiae trichotomae of 45～70 parts of Radix Polygoni Multiflori of 45～75 parts of Cortexs Eucommiae of Semen Ginkgo
30～50 parts, 35～50 portions of Auricularias of 35～55 parts of Lentinus Edodess of 40～60 portions of Radix Dauci Sativaes of Radix Salviae Miltiorrhizae
20～35 parts of 20～40 portions of Germinatus Phragmitiss of 25～40 portions of Thallus Gracilariaes of 25～45 portions of Fructus Crataegis of Herba Urticae Cannabinae.
3. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
55～70 parts of 60～70 parts of Amaranthus mangostanus L.s of 60～75 parts of Radix Puerariaes of 70～75 portions of Rhizoma Dioscoreaes of Semen Sesami Nigrum
45～60 parts of 50～60 parts of Folium Evodiae trichotomae of 50～65 parts of Radix Polygoni Multiflori of 50～70 parts of Cortexs Eucommiae of Semen Ginkgo
35～45 parts, 40～45 portions of Auricularias of 40～50 parts of Lentinus Edodess of 45～55 portions of Radix Dauci Sativaes of Radix Salviae Miltiorrhizae
25～30 parts of 25～35 portions of Germinatus Phragmitiss of 30～35 portions of Thallus Gracilariaes of 30～40 portions of Fructus Crataegis of Herba Urticae Cannabinae.
4. a kind of Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
63 parts of 65 parts of Amaranthus mangostanus L.s of 67 parts of Radix Puerariaes of 72 portions of Rhizoma Dioscoreaes of Semen Sesami Nigrum
52 parts of 55 parts of Folium Evodiae trichotomae of 60 parts of Radix Polygoni Multiflori of 60 parts of Cortexs Eucommiae of Semen Ginkgo
40 parts, 42 portions of Auricularias of 45 parts of Lentinus Edodess of 50 portions of Radix Dauci Sativaes of Radix Salviae Miltiorrhizae
28 parts of 30 portions of Germinatus Phragmitiss of 32 portions of Thallus Gracilariaes of 35 portions of Fructus Crataegis of Herba Urticae Cannabinae.
5. as described in claim 1～4 any one, treat a preparation method for the Chinese medicine preparation of cardiovascular and cerebrovascular disease, it is characterized in that: comprise following processing step:
(1) by Semen Sesami Nigrum, Radix Puerariae, Radix Salviae Miltiorrhizae and Auricularia decontamination, microwave drying, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(2) Rhizoma Dioscoreae, Semen Ginkgo, Folium Evodiae trichotomae, Lentinus Edodes, Herba Urticae Cannabinae and Thallus Gracilariae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that under 60 ℃ of environment, relative density is 1.10～1.16, standby;
(3) Amaranthus mangostanus L., Radix Dauci Sativae, Fructus Crataegi and Germinatus Phragmitis are cleaned, put into container, strand juice, filter impurity, stays juice standby;
(4) Cortex Eucommiae and Radix Polygoni Multiflori decontamination are cleaned, immersed 85% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and is condensed into the thick paste that under 70 ℃ of environment, relative density is 1.20～1.25, standby;
(5) above-mentioned steps (1)～(4) prepared fine powder, thick paste and juice are mixed, utilize modern advanced pharmacy science and technology, make tablet, obtain the Chinese medicine preparation for the treatment of cardiovascular and cerebrovascular disease of the present invention.
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| CN103623280B (en) | 2015-08-05 |
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