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CN106163378A - Portable wavefront analyzer - Google Patents

Portable wavefront analyzer Download PDF

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Publication number
CN106163378A
CN106163378A CN201480073991.4A CN201480073991A CN106163378A CN 106163378 A CN106163378 A CN 106163378A CN 201480073991 A CN201480073991 A CN 201480073991A CN 106163378 A CN106163378 A CN 106163378A
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CN
China
Prior art keywords
module
polished rod
light
mobile device
patient
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CN201480073991.4A
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Chinese (zh)
Inventor
周垚鹏
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Intelligent Visual Laboratory
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Intelligent Visual Laboratory
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Publication of CN106163378A publication Critical patent/CN106163378A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1015Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for wavefront analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14Arrangements specially adapted for eye photography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J1/00Photometry, e.g. photographic exposure meter
    • G01J1/42Photometry, e.g. photographic exposure meter using electric radiation detectors
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B3/00Simple or compound lenses
    • G02B3/0006Arrays
    • G02B3/0037Arrays characterized by the distribution or form of lenses
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04MTELEPHONIC COMMUNICATION
    • H04M1/00Substation equipment, e.g. for use by subscribers
    • H04M1/72Mobile telephones; Cordless telephones, i.e. devices for establishing wireless links to base stations without route selection
    • H04M1/724User interfaces specially adapted for cordless or mobile telephones
    • H04M1/72403User interfaces specially adapted for cordless or mobile telephones with means for local support of applications that increase the functionality
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J9/00Measuring optical phase difference; Determining degree of coherence; Measuring optical wavelength
    • G01J2009/002Wavefront phase distribution

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Human Computer Interaction (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

A kind of module for being used together to measure the aberration of the eyes of patient with mobile device (504) includes the polished rod (501) with near-end (502) and far-end (503), and light source (213,506).Polished rod (501) includes being arranged to along from more than first optical module (205,206,209,210,213,314,316) of the first light path (211) direct light of light source (213,506) to near-end (502), and is arranged to more than second optical module (206,207,208,214) along proximally the second light path (212) direct light of the photodetector (220,506) of (502) to mobile device (504).The adapter (507) at far-end (503) place includes at least one guide assembly (508), for far-end (503) is positioned adjacent to photodetector (220,506).When far-end (503) is positioned adjacent to photodetector (220,506), more than first optical module (205,206,209,210,213,314,316) is along the first light path (211) direct light, and more than second optical module (206,207,208,214) is along the second light path (212) direct light.

Description

Portable wavefront analyzer
Cross-Reference to Related Applications
This application claims the preferential of U.S. Provisional Patent Application No.61/922,337 submitted to for 31st in December in 2013 Power.
Technical field
The realization of the disclosure relates to the optical device of the refractive error of the eyes of detection and measurement patient.
Background technology
In the U.S., provide eyesight testing the most routinely for the child of less than 6 years old, wherein in the child of less than 6 years old only 14% once had eyesight testing.It addition, suffer the relevant disease of refractive error in world wide more than 500,000,000 people, wherein these People is in developing country more than 90%.Without EARLY RECOGNITION and correct, then this situation is the most more Add deterioration.
Some factors may stop detection in early days and general detection.One factor is exchange, can not as being probably child Clearly illustrate the disease that he/her is standing situation or in developing country patient may not effectively with doctor Treat the situation that supplier carries out exchanging.Another factor is cost, and this is to limit especially in developing country, this is because For detect the equipment of refractive error be probably costliness and for operate equipment analysis result through well trained Personnel are probably un-come-at-able or have finite availability.
Accompanying drawing explanation
To carry out the disclosure is shown by example, non-limiting in each figure of accompanying drawing, wherein same reference numerals instruction Similar element, and wherein:
Fig. 1 depicts eyes, by the wavefront of photogenerated reflected from eye retina and this light is focused on movement Lens arra on the photodetector of equipment photographing unit;
Fig. 2 illustrates the design of disclosed wavefront analyzer;
Fig. 3 illustrates the design of the replacement of disclosed wavefront analyzer;
Fig. 4 depicts the Shack Hartmann (Shack-corresponding to normal eye He the eyes with refractive error Hartmann) difference of hot spot, and represent defocus the wavefront profile shape with astigmatism;
Fig. 5 is the signal of the realization of module and the mobile device that is associated;
Fig. 6 A depicts according to a view realizing the exemplary module used;
Fig. 6 B depicts according to another view realizing the exemplary module used;And
Fig. 7 is to use any one in realization disclosed herein for measuring the schematic of the aberration of the eyes of patient Process.
Detailed description of the invention
The theme of the application is made the eyes for detecting and measure patient by ophthalmologists and optometrist with relating to most typically The diagnostic device of refractive error.More particularly, the theme of the application relates to be reversibly attached to portable computing device (such as smart phone) thus create the module of function wavefront analyzer.The theme of the application utilizes and is such as found in module The light source of laser generates will be from the light of eye reflections.Further, the photograph of disclosed equipment utilization portable computing device Camera captures this reflection light, and then it can be changed and be provided to the special people of medical matters by the software on portable computing device Member and other people use.
One purpose of subject matter is to provide a kind of module, and it is to be reversibly coupled to portable computing device (all Such as smart phone) time create function wavefront analyzer.Further objective is that by utilizing consumer may have just Formula of taking calculates equipment to provide the wavefront analyzer of lower cost.Another object is to provide the wavefront analyzer mould of lower cost Block, it can be marked brand by optics experts and lend patient's use to provide for optics experts and following the tracks of patient's Multiple data sets of the change of the refractive error of eyes.Another purpose is to provide the wavefront analyzer module of lower cost, its Brand can be marked by optics experts and lend patient to allow this patient in the situation without visiting optics experts Lower acquisition dioptometry, and it is alternatively possible to those measurement results are sent to optics experts for diagnosis or sieve Look into purpose, or make or be ready to the correcting lens bought.The character of realization disclosed herein can reduce and wave front aberration The cost that instrument is associated so that it becomes a kind of and uses for family or such as develop in the region of limited medical infrastructure Viable device in Chinese Home.
These purposes can be passed through wavefront analyzer module (" module ") and obtain, and it can be reversibly attached to mobile meter Calculation equipment (" mobile device "), such as smart phone, personal digital assistant, kneetop computer or palmtop computer.Smart phone It it is the mobile phone with computer, lighting screen and photographing unit and other features.Theme according to the application can use to be had Other mobile devices of photographing unit.Such as, can be to be equipped with photographing unit according to the disclosed spendable mobile device that realizes Phone (or smart phone), although be used as such as panel computer, kneetop computer, special audio or video player, And other equipment of E-book reader, they can include photodetector (such as, photographing unit), and, central authorities process Unit or for by the information captured by photographing unit transmission to the transceiver of another equipment with CPU.Described mould Block can include for by this module location or be attached to the guiding piece of mobile device, thus provide and make the light from light source can court The beam path that the eyes of patient are directed, and the light row that eye reflections from light source, by patient is left is provided Enter through microlens array the beam path that arrives soon after on photodetector.
Some isolation of components of wavefront analyzer is formed functional unit for being bonded together by the theme of the application Two assemblies.One assembly, described module, including focusing the light into and guide the system of the eyes to patient, and will be from patient The light of eye reflections be directed across lens arra and eventually arrive at the system of photodetector of the part including mobile device.Should Separating the major advantage allowing subject matter, this major advantage is that cost and the complexity of wavefront analyzer are divided into module Part and mobile device part, described mobile device part is probably that had or obtainable for consumer.
In use, this module can be reversibly attached to mobile device and be held in place so that the light source from module Light beam is focused on the eyes of wearer by module.Time in place, the light source of module is activated, and causes the amphiblestroid of wearer Reflection also passed microlens array before the photographing unit of final mobile device detects.The data collected by photographing unit are then Can be processed by the pico computer of mobile device by algorithm known in the art, or data can be sent to by mobile device Different computers processes.Data can be presented to terminal use with untreated form, or its can process after form Present, such as eyeglass lens power (eyeglasses prescription) or Si Nielun mark (Snellen fraction).Mobile Software on equipment can also limit and present the information to terminal use, and sends special to optics by untreated or reduced data Industry personnel are for diagnostic uses and/or prepare correcting lens.
Some realization of the disclosure relates to be used together to measure the mould of the aberration of the eyes of patient with mobile device Block.In one aspect, this module includes the polished rod (light shaft) having proximally and distally.This polished rod can include being arranged For edge from more than first optical module of the first light path direct light of far-end to near-end, and it is arranged to along proximally to far-end More than second optical module of the second light path direct light.In some implementations, at least some of in the first and second light paths It is coextensive.This module can include light source and adapter further.Adapter can be located at the far-end of polished rod.Adapter At least one guide assembly can be included, for by the remotely located photodetector for proximate mobile devices of polished rod.Real at some In Xian, when the far-end of polished rod is positioned adjacent to the photodetector of mobile device, more than first optical module be configured to by Light from light source guides the near-end to polished rod along the first light path, and more than second optical module is configured to light along second Light path guides the photodetector to mobile device from the far-end of polished rod.
In some implementations, more than second optical module includes microlens array.
In some implementations, polished rod has tubular form.
In some implementations, adapter includes the plate with proximal face and distal surface, and polished rod is from this plate The continuous extension that proximal face proximad extends.The far-end of polished rod limits the opening through plate.
In some implementations, at least one guide assembly described is arranged along the periphery of plate.
In some implementations, when the far-end of polished rod is positioned adjacent to the photodetector of mobile device, described plate remote Side surface adjoins at least part of surface of mobile device.
In some implementations, at least one guide assembly described is the groove for receiving mobile device.
In some implementations, at least one guide assembly described is configured to be anchored in a part for mobile device.
In some implementations, at least one guide assembly described is configured to be detachably attached to described module described Mobile device.
In some implementations, described light source is contained in polished rod.
In some implementations, described light source is laser instrument.
In some implementations, described module farther includes the receiving port for light source is installed to described module, its Middle polished rod is configured to when light source is in receiving port guide the light from light source.
In some implementations, described module farther includes the battery port for accommodating battery.Battery port can be by It is configured to when battery is in battery port cell electrical is connected to light source.
In some implementations, the signal that the light source of described module is configured to respond to from mobile device receives generates Light.
In yet another aspect, a kind of method for the aberration of the eyes measuring patient includes being positioned adjacent to module move Dynamic equipment is so that the photodetector of far-end proximate mobile devices of polished rod of module.The method farther includes to position module For the eyes of neighbouring patient so that the near-end of polished rod is adjacent to the eyes of patient.The method farther includes the light from module The light in source is directed across polished rod the eyes towards patient.The method farther includes to guide from the light of the eye reflections of patient Through polished rod to the photodetector of mobile device.
In some implementations, being included by the remotely located photodetector for proximate mobile devices of polished rod can by described module Releasably it is attached to mobile device.
In some implementations, the method farther includes to process in response to being directed across from the light of the eye reflections of patient The data that polished rod generates to the photodetector of mobile device.
In some implementations, process data and include measuring the retinal disparity of patient.
In some implementations, process data include using realize on the mobile apparatus should be for processing data.
In some implementations, the method farther includes to transfer data to separate equipment, and processes data and include Described separate equipment is used to process data.
Description below and herein by reference to accompanying drawing illustrate the realization of subject matter, and be not intended to restriction scope. It will be appreciated by those of ordinary skill in the art that is, and other realizations of disclosed method are possible.All these realizations all should It is considered within the scope of claims.Each reference is made up of three numerals.First first digit correspondence is shown Go out the accompanying drawing number of this reference.Reference is not necessarily discussed with they appearance orders in the accompanying drawings.
Fig. 1 depicts the simple overall of the aspect of realization, and wherein, light wavefront (103) luminous reflectance represented leaves patient The retina (102) of eyes (101).This light (103) is separated into spot array and by lenticule battle array by microlens array (104) Row focus in two-dimensional photodetector (105).As shown in this signal, two-dimensional photodetector can be mobile device (such as intelligence Can phone) photographing unit.It should be understood that in this realization, the combination of this module and smart phone should be by claims It is limited to use smart phone, but arbitrarily mobile device can be used together with module the most disclosed herein.
Fig. 2 and 3 is the diagram of optical module in described module and shows from its section start to it in two-dimensional photodetector (220) light path received on, the photodetector (105) of two-dimensional photodetector (220) such as Fig. 1.
In some implementations, the light source (213) of module, such as laser, it is briefly opened up.In some implementations, light can be worn Cross aperture diaphragm (209) to reduce the radius of light beam.As shown in Figure 3, light path is guided and optional by reflecting mirror (210,205) Ground focuses on as desired by through lens (314,316).In some implementations, it is convenient to omit one or more reflecting mirrors (205,210), and light source (213) is placed in correct position to guide light beam towards beam splitter (206).
Light source (213) can have substantially low energy, and its time exposure will not the eyes of injured patient.This can allow User is opened light source (213) and makes it stay open when carrying out one or more measurement when measuring and starting.Alternately, Module can include switch, and it can be cut in response to the signal (such as, bluetooth or the signal of similar type) sent from mobile device Change the power supply of light source (213), or can be triggered by the glittering of the flash of light of mobile device.In some implementations, available shutter Stop from the light of light source (213) till measuring.Can be by being reversibly connected to the battery of module to light source (213) Supply energy, or energy can obtain from mobile device.
By guiding light beam and subsequently by reflecting mirror (205) direct light first by illuminator (210) along the first light path Restraint to beam splitter (206) so that the eyes to patient will be guided from the light beam of light source (213).Optional lens (314,316), anti- Penetrate mirror (205,210), aperture diaphragm (209), beam splitter (206) and light source (213) can referred to collectively as " optical module " or " more than first optical module ", it limits the first light path that light beam marches to the retina (201) of patient from light source (213) (211).The plurality of optical module is not restricted to shown those, and the lens that can include as required adding, beam splitter, Reflecting mirror and aperture.
Reflection and the absorbance that can select beam splitter (206) are transported to eyes with the light of permission q.s.For really Surely the abundance of the light of eyes it is delivered to and by changing the reflection of beam splitter and the technology of amount that absorbance changes light exists Association area is known.
After beam splitter (206), collimated light is directed at the eyes of patient, here its enter pupil (204) and Focused on retina (201) by cornea (202) and crystalline lens (203).Collimated light be reflect off retina (201) and along with Leave pupil (204) and again pass through crystalline lens (203) and cornea (202).Therefore, after retina light along light path (212) through point Bundle device (206) also then passes through microlens array (214), the microlens array (104) of such as Fig. 1.Microlens array (214) wraps Including multiple lens, light is split and is converted to the two dimension of the hot spot of each self-focusing at the focal plane of microlens array (214) by it Array (" spot array ").Produced spot array then passes through lens (207) and lens (208).These lens (207, 208) at the upper conjugate image plane producing spot array of photodetector (220).In some implementations, photodetector is complementary gold Belong to oxide semiconductor (CMOS) or charge-coupled image sensor (CCD).In some implementations, lens (208) and photodetector (220) It it is the assembly of mobile device.Lens (208) can be the camera gun of the mobile device being associated, and also can include one Series of lenses.
Lens (207,208), microlens array (214) and beam splitter (206) can also be collectively referred to as " optics Assembly " or " more than second optical module ", it limits and marches to the of photodetector (220) for light beam from the retina of patient Two light paths.It should be understood by one skilled in the art that be the first and second light paths be coextensive at least partially. Term " coextensive " means that the volume that at least two limits can occupy identical space.Such as, two paths are at path base It is considered as coextensive when this is parallel and overlapping.
Although the precision of wavefront aberrometer along with in microlens array the increase of lens numbers and increase, and increase the quantity of lens It is likely to reduced the dynamic range (amplitude of optical aberration) of equipment.Relatively low dynamic range can stop wavefront aberrometer to measure big picture Difference.The quantity of wavefront aberrometer lens can be limited further by each lenticular size and the size of the light beam entering microlens array System.In some implementations, the diameter of the light beam of entrance microlens array (214) is between about 2 millimeters and about 5 millimeters, and this is right Should be in the size of the unexpanded pupil (204) of patient, and microlens array (214) can include between 5 to 25 of X-axis Lens, and along the lens between 5 to 25 of Y-axis.In some implementations, microlens array (214) can include 5 along X-axis Lens between 20, and along the lens between 5 to 20 of Y-axis.In some implementations, along the lens of X-axis of array Quantity is identical with the lens numbers along Y-axis.
Fig. 3 shows the design of the replacement of optical module in module.Fig. 3 Yu Fig. 2 difference is to include optical lens (314、316).The many realization of module does not include these assemblies, partly decreases manufacturing cost, and partly minimizes The size of module.
Microlens array (214) is placed in the tens of milliseconds of pupil (204) by the optical design of Fig. 2 and 3, this distance is put In Rayleigh distance (Rayleigh range) used in near-field propagation, even if thus being not at pupil at microlens array Conjugate planes in time also provide for the reasonable measurement of aberration.This is at Bauman, B.J. , &Eisenbies, S.K. (2006), " Adaptive Optics System Assembly and Integration, " at Porter, J., et al (Ed.), Adaptive Optics for Vision Science:Principles, Practices, Design, and Applications, Wiley-Interscience, pp 155-187 is described.Such as United States Patent (USP) No.6,264,328 Described in, the design of replacement is increase lens pair between pupil (204) and microlens array (214).These lens are to micro- The upper conjugate image plane forming pupil of lens array (214), this generates by photodetector (220) the optical aberration of eyes Accurately measure.
Fig. 4 illustrates can the photographing unit of how mobile device to be captured and by data from the light of patient's retinal reflex The example of the produced profile diagram of conversion.As described, from the light of retinal reflex along with it is through microlens array (410) (all the most arbitrarily microlens arrays) is converted to spot array (401,402).If eyes do not have aberration (such as left eye (411)), the photographing unit of mobile device the produced spot array captured can be by equally distributed hot spot (401) composition.If contrary, eyes have aberration (such as, right eye (412)), and the spot array of produced acquisition can have The hot spot distribution of distortion.
The image of spot array can by by mobile device from the most with it computer or by obtaining from mobile device The computer (jointly, " computer ") of image uses algorithm known in the art to carry out mathematics conversion.A kind of such turn Change and can produce the profile diagram representing eyes (403) aberration.Spot array can also be transformed to may be used for wound by computer Build the eyes number of degrees of correcting lens (404) for patient.
Although the main source being reflect off the light of the eyes of patient is to be reflect off amphiblestroid light, and reflect the secondary of light Originate is to be reflect off patient's retina or lenticular light.This cornea or lenticular reflection light (" noise ") can be Deducted by computer during process or additionally by using method and technology known to association area to minimize.
Fig. 5 is the signal of module and the realization of the mobile device being associated.In some implementations, in housing (i.e. " polished rod ") Comprise the optical module of module.In some implementations, polished rod can be tubulose (i.e. " light pipe "), all light as depicted in Figure 5 Bar (501).Polished rod (501) is included in the eyeshield on one end (" patient end " or " near-end ") (502), and at the other end (" equipment End " or " far-end ") at least one opening on (503).Equipment end is adjoined and is passed through adapter and is reversibly connected to mobile device (504).In some implementations, adapter includes the backboard with at least one guide assembly (508) (such as, locating guide) (507).Such as, guide assembly (508) can position along the periphery of backboard (507).In some implementations, it may include at least two or Three guide assembly.Same as described, in use, guide assembly is reversibly attached to mobile device so that moves and sets Standby photodetector or photographing unit (506) are directed at the optical module comprised in polished rod (501), thus receive from patient's retina The light of reflection.
In some implementations, in polished rod (501), also comprise the LASER Light Source of module, although the design substituted can have The laser instrument in polished rod (501) outside.Such as, LASER Light Source can neighbouring polished rod (501), and adjoint optical module can be by light Guide to polished rod (501) from LASER Light Source.It addition, polished rod (501) can also include user-accessible can keep laser instrument The battery compartment of power supply.In some implementations, the light source of module by mobile power supply equipment, and can receive letter from mobile device Number (by being connected or wireless receiver with the direct physical of mobile device) is to produce light.In some implementations, light source is detachable Be attached to the receiving port of module.
In some implementations, polished rod (501) can be the continuous extension of backboard (507), and it is from the nearside table of backboard (507) Extend towards nearside.The equipment end (503) of polished rod (501) can limit the opening through backboard (507) so that from the eyes of patient The light of reflection can pass.In some implementations, the far-end at polished rod (501) is positioned adjacent to the light of mobile device (504) During detector, the distal surface of backboard (507) can adjoin at least part of surface of mobile device (504).
In some implementations, guide assembly (508) can allow backboard (507) to be anchored in mobile device.In some implementations, Backboard (507) can include two guide assembly (508) being arranged on contrary side, and it allows backboard (507) to slide into mobile setting On standby (504).In this implementation, the 3rd guide assembly can be located at top margin or the base of backboard (507), and it stops further Slide with the photodetector (506) that polished rod (501) is positioned adjacent to mobile device (504).In some implementations, can be integrally Omit backboard (507).Such as, a part for polished rod (501) can directly be anchored in mobile device (504).In some implementations, example As shown in Figure 6 A and 6B, guide assembly (508) can be groove, and this groove is the widest to receive and to keep mobile device (504) A part.In some implementations, the adapter of location polished rod (501) can be to cause polished rod (501) to adhere to mobile device (504) adhesive material.In such an implementation, adhesive material can be arranged in the distal surface of backboard (507).At some In realization, adapter can include multiple sections of the remote extension from polished rod (501) and is configured to engagement and/or is wound around mobile setting Standby (504).In some implementations, adapter can include indicating how by polished rod (501) about photodetector (506) position right Fiducial mark is remembered.
It should be understood that the tubular form of polished rod (501) is only the schematic example of polished rod, arrange the optics group of module The arbitrary structures of part, such as closed shell, partial closure's sandwich type element (such as, as depicted in fig. 6 a), plate or it is any Suitably combination, all can be seen as polished rod.
It is contained in accurately constructing and be sized to by using side known in the art of the optical module in polished rod (501) Formula and technology determine.In some implementations, the opening at the location of optical module and the equipment end of polished rod (501) is manufacturing Period is by fixed position so that opening is corresponding to the position of the camera gun of mobile device, so that outside or reflection Light path be directed at the camera gun of mobile device.
In use, the equipment end of polished rod (501) can reversibly be connected to mobile device, and the trouble of polished rod (501) Person's end is held against the eye socket of patient.When the light source of module activated, the light from light source is advanced as disclosed To the retina of patient, and this light is reflected onto the photographing unit of mobile device the most in the manner disclosed.By photodetector Or the data mobile device (such as, the application by running in mobile device) of photographing unit capture is handled, or it is transferred into Another computer is for process.In this way, if the realization of software allows, then patient can monitor they self refraction or Si Nielun mark.Other of software realize to pass data to medical supplier for diagnosing or monitoring purpose, maybe can be by Data are transferred to correcting lens supplier for providing the purpose of correcting lens for patient.Such as wavefront picture described herein Difference instrument module allows for that patient obtains the measurement of retinal disparity and without going to the office of ophthalmologist or optometrist, this can The compliance that proposed refraction is measured can be increased.
Fig. 7 is to use any realization disclosed herein to measure the illustrative process of the aberration of the eyes of patient.This process (700) step (702) is started from.In step (704), the far-end of the polished rod of module is positioned adjacent to the light detection of mobile device Device.Polished rod may correspond to any realization disclosed herein, the polished rod (501) of such as Fig. 5 or the polished rod of Fig. 6 A.Mobile device is permissible It is any type of mobile device described herein, the mobile device (504) of such as Fig. 5.In some implementations, can by by Polished rod is removably attached to mobile device and polished rod is disposed adjacent to the photodetector of mobile device, adapter by adapter It is such as the backboard (507) in Fig. 5 and guide assembly (508).
In step (706), the near-end of polished rod is positioned adjacent to the eyes of patient.Such as, near-end can adjoin the eye of patient Eyeball or to be placed in certain distance outer not physically contact with patient.Near-end can be similar to hold (502) and can have eyeshield.
In step (708), the light from the light source of module is guided through polished rod the eyes towards patient.This such as may be used By using more than first optical module to complete, the optional lens of more than first optical module such as Fig. 2 and 3 (314, 316), aperture diaphragm (209), reflecting mirror (205,210) and beam splitter (206).
In step (710), it is conducted through polished rod to the photodetector of mobile device from the light of the eye reflections of patient.This Such as can complete by using more than second optical module, the lens of more than second optical module such as Fig. 3 (207,208, 214,314,316), pinhole diaphragm (315) and beam splitter (206).
In some implementations, mobile device self (using the processor of mobile device) or separate equipment can such as be passed through Process in response to guiding the data generated to photodetector from the light of the eye reflections of patient.Data process can include root The retinal disparity of patient is measured according to method described herein.In separate equipment processes the realization of data, mobile device can It is configured to transmit (processed or untreated) data to separate equipment.
Word used herein " example " or " exemplary " are used for being denoted as example, example or signal.Retouch herein State as " example " or any aspect of " exemplary " or design is not necessarily construed to compare other aspects or design is preferred Or it is favourable.But, use word " example " or " exemplary " to be intended to introduce concept with concrete form.As the application makes , term "or" is intended to indicate that the "or" of pardon rather than the "or" of exclusiveness.It is to say, unless otherwise specified, or From context clearly, " X includes A or B " is it is intended that represent the arrangement arbitrarily naturally included.If it is to say, X includes A, X A and B is included, then meet " X includes A or B " under any aforementioned circumstances including B or X.It addition, in the application and institute The article " one " used in attached claims and " one " (" a " and " an ") should be interpreted as representing " one or many by ordinary solution Individual ", it is unless otherwise specified or understands for representing odd number from context.For " realization " or " realization " in entire disclosure Mention expression combine special characteristic, structure or the characteristic described by this realization be included at least one realize in.Therefore, exist In each place in entire disclosure, phrase " realizes " or the appearance of " realization " need not all refer to identical realization.
Be construed as foregoing description it is intended that schematically, and and nonrestrictive.Reading and understanding foregoing description After, other realizations many will be apparent from for a person skilled in the art.Therefore the scope of the present disclosure should refer to add Claim determine together with the complete scope of the equivalent of these claim institute entitles.

Claims (20)

1., for being used together to measure a module for the aberration of the eyes of patient with mobile device, this module includes:
Having polished rod proximally and distally, polished rod includes: be arranged to along from the of the first light path direct light of far-end to near-end More than one optical module, and it is arranged to along proximally to more than second optical module of the second light path direct light of far-end, Wherein, described first and second light paths are coextensive at least partially;
Light source;And
Being positioned at the adapter of the far-end of polished rod, described adapter includes at least one guide assembly, for by the far-end of polished rod Being positioned adjacent to the photodetector of mobile device, wherein, the far-end at polished rod is positioned adjacent to the photodetector of mobile device Time:
More than first optical module is configured to guide the near-end to polished rod from the light of light source along the first light path, and
More than second optical module is configured to from the far-end of polished rod, light is guided the light detection to mobile device along the second light path Device.
Module the most according to claim 1, wherein, described more than second optical module includes microlens array.
3. according to the module according to any one of claim 1 or 2, wherein, polished rod has tubular form.
Module the most according to any one of claim 1 to 3, wherein, described adapter includes having proximal face with remote The plate of side surface, wherein, polished rod is the continuous extension extended from the proximal face proximad of this plate, and wherein, polished rod remote End limits the opening through described plate.
Module the most according to claim 4, wherein, at least one guide assembly described is arranged along the periphery of described plate.
Module the most according to claim 4, wherein, the far-end at polished rod is positioned adjacent to the photodetector of mobile device Time, the distal surface of described plate adjoins at least part of surface of mobile device.
Module the most according to claim 6, wherein, at least one guide assembly described is for receiving mobile device Groove.
Module the most according to claim 6, wherein, at least one guide assembly described is configured to be anchored to mobile device In a part.
Module the most according to any one of claim 1 to 8, wherein, at least one guide assembly described be configured to by Described module is detachably attached to mobile device.
Module the most according to any one of claim 1 to 9, wherein, described light source is contained in polished rod.
11. modules according to any one of claim 1 to 10, wherein, described light source is laser instrument.
12., according to the module according to any one of claim 1 to 11, farther include:
For light source is installed to the receiving port of described module, wherein, polished rod is configured in light source is in receiving port Time guide from the light of light source.
13., according to the module according to any one of claim 1 to 12, farther include:
For accommodating the battery port of battery, wherein, battery port is configured to battery when battery is in battery port It is electrically connected to light source.
14. according to the module according to any one of claim 1 to 13, and wherein, the light source of described module is configured to respond to The signal received from mobile device generates light.
15. 1 kinds are used for the method measuring the aberration of the eyes of patient, and described method includes:
Module is positioned adjacent to mobile device, so that the photodetector of the far-end proximate mobile devices of the polished rod of module;
Module is positioned adjacent to the eyes of patient, so that the near-end of polished rod is adjacent to the eyes of patient;
The light of the light source from module is directed across polished rod the eyes towards patient;And
Light from the eye reflections of patient is directed across polished rod to the photodetector of mobile device.
16. methods according to claim 15, wherein, by the remotely located photodetector for proximate mobile devices of polished rod It is detachably attached to mobile device including by described module.
17. according to the method according to any one of claim 15 or 16, farther includes to process in response to by from the eye of patient The light of eyeball reflection is directed across the data that polished rod generates to the photodetector of mobile device.
18. methods according to claim 17, wherein, process data and include measuring the retinal disparity of patient.
19. methods according to claim 17, wherein, process data include using realize on the mobile apparatus should be for Process data.
20. methods according to claim 17, farther include to transfer data to separate equipment, wherein, process number Use described separate equipment to process data according to including.
CN201480073991.4A 2013-12-31 2014-10-06 Portable wavefront analyzer Pending CN106163378A (en)

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CA2935292A1 (en) 2015-07-09
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EP3089651A1 (en) 2016-11-09
AU2014374398B2 (en) 2019-05-09
JP2017504408A (en) 2017-02-09
MX2016008609A (en) 2016-11-28
JP2019111443A (en) 2019-07-11
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RU2016131389A (en) 2018-02-06
AU2014374398A1 (en) 2016-07-07

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