CN106110447A - A kind of new medical painless syringe syringe needle - Google Patents
A kind of new medical painless syringe syringe needle Download PDFInfo
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- CN106110447A CN106110447A CN201610570360.4A CN201610570360A CN106110447A CN 106110447 A CN106110447 A CN 106110447A CN 201610570360 A CN201610570360 A CN 201610570360A CN 106110447 A CN106110447 A CN 106110447A
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- 230000001788 irregular Effects 0.000 claims abstract description 7
- 241000255925 Diptera Species 0.000 abstract description 11
- 238000002347 injection Methods 0.000 abstract description 8
- 239000007924 injection Substances 0.000 abstract description 8
- 238000005516 engineering process Methods 0.000 abstract description 5
- 239000011664 nicotinic acid Substances 0.000 abstract description 5
- 230000000638 stimulation Effects 0.000 abstract description 3
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 230000009467 reduction Effects 0.000 description 9
- 210000003491 skin Anatomy 0.000 description 9
- 210000002615 epidermis Anatomy 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 3
- 241000254137 Cicadidae Species 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000010999 medical injection Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 241000931705 Cicada Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 206010022086 Injection site pain Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 210000003323 beak Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 210000001723 extracellular space Anatomy 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000000968 medical method and process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 230000007383 nerve stimulation Effects 0.000 description 1
- 210000000929 nociceptor Anatomy 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/04—Skin
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
本发明公开了一种新型医用无痛注射器针头,本发明所述注射器针头的管壁表面设置有不规则表面,所述不规则表面具体为凹坑型、锯齿型和波纹型,所述凹坑型的管壁表面均匀分布多个凹坑,所述锯齿型的管壁表面分段均匀设置多组锯齿段,所述波纹型的管壁为整条针管呈波纹型。与现有技术相比,本发明通过蚊子仿生技术研制,和注射针头平滑的片面相比,改进后的注射器和皮肤组织接触的面积较小,减少了对神经的刺激,使注射产生的疼痛感大大降低,进而提高其使用的便捷程度。关键问题在于如何将针头做成锯齿状微米结构,减少对皮肤的摩擦,同时尽可能实现资源再利用。具有推广应用的价值。
The invention discloses a novel medical painless syringe needle. The surface of the tube wall of the syringe needle described in the invention is provided with an irregular surface. A plurality of pits are evenly distributed on the surface of the tube wall of the zigzag type, and multiple groups of sawtooth segments are uniformly arranged on the surface of the zigzagging tube wall, and the corrugated tube wall is that the entire needle tube is corrugated. Compared with the prior art, the present invention is developed through the mosquito bionic technology. Compared with the smooth surface of the injection needle, the improved syringe has a smaller contact area with the skin tissue, which reduces the stimulation of the nerves and makes the injection painful. Greatly reduced, thereby improving the convenience of its use. The key issue is how to make the needles into a jagged micron structure to reduce friction on the skin while reusing resources as much as possible. It has the value of promotion and application.
Description
技术领域technical field
本发明涉及一种医疗注射器,尤其涉及一种新型医用无痛注射器针头。The invention relates to a medical syringe, in particular to a novel medical painless syringe needle.
背景技术Background technique
皮下注射是当前较为常见的医疗方法,该方法为使用注射器刺破人体皮肤将药物直接输入体内。在注射医疗过程中,针头刺入人体内产生的疼痛感跟人体皮肤内的感觉器官有关。人体皮肤由表皮,真皮和皮下组织三部分组成,痛觉感受器位于表皮内,其髓神经纤维进入表皮即失去神经膜,并分支成网状或小球状,分散于表皮细胞间隙内,在皮肤表面有痛点存在,分布密集,所以表皮痛觉特别敏感。感受器取决于刺激的强度,变化速率,作用时间,作用面积四个因素,注射时决定疼痛的四个因素中变化速率和作用时间与注射器针头无关,作用面积取决于针头型号,因此刺激的强度是注射痛觉感中唯一可以改变的因素。Subcutaneous injection is a relatively common medical method at present, which uses a syringe to puncture the skin of the human body to directly inject the drug into the body. In the medical injection process, the pain caused by the needle piercing the human body is related to the sensory organs in the human skin. Human skin is composed of three parts: epidermis, dermis and subcutaneous tissue. Pain receptors are located in the epidermis. When the medullary nerve fibers enter the epidermis, they lose the nerve membrane and branch into reticular or small balls, scattered in the intercellular space of the epidermis. Pain points exist and are densely distributed, so the epidermis is particularly sensitive to pain. Receptors depend on four factors: intensity of stimulation, rate of change, time of action, and area of action. Among the four factors that determine pain during injection, the rate of change and action time have nothing to do with the needle of the syringe. The area of action depends on the type of needle, so the intensity of stimulation is The only modifiable factor in the sensation of injection pain.
从当前市场看,现在尚未有一种减痛效果优,加工工艺成熟,价格合理,同时在药物临床作用效果方面,可以完全取代普通注射器的产品。Judging from the current market, there is not yet a product with excellent pain relief effect, mature processing technology, reasonable price, and can completely replace ordinary syringes in terms of clinical effects of drugs.
另一方面,从仿生学的角度来看,蚊子的口器呈锯齿状,和注射针头平滑的片面相比,锯齿状的口器和皮肤组织接触的面积较小,减少了对于神经的刺激,所以产生的疼痛感大大降低。蚊子的口器刺入皮肤后,分泌出的唾液含有抗凝血的物质,让它能够尽情的吸血。事实上,蚊子能够在人体完全没有感觉的状况下完成叮咬的动作。On the other hand, from the perspective of bionics, the mouthparts of mosquitoes are jagged. Compared with the smooth side of the injection needle, the jagged mouthparts have a smaller contact area with skin tissue, which reduces nerve stimulation. So the pain is greatly reduced. After the mosquito's mouthparts penetrate the skin, the saliva secreted contains anticoagulant substances, allowing it to suck blood as much as possible. In fact, mosquitoes can complete the bite without the human body feeling at all.
基于上述情况,本发明拟研制一种模仿蚊子口器的医用注射针头,这种针头在扎进皮肤的时候不会让人感到疼痛,非常适合用于开发新型医用注射器。Based on the above situation, the present invention intends to develop a medical injection needle that imitates the mouthparts of mosquitoes. This needle will not make people feel pain when pierced into the skin, and is very suitable for developing new medical syringes.
发明内容Contents of the invention
本发明的目的就在于为了解决上述问题而提供一种新型医用无痛注射器针头。The object of the present invention is to provide a novel medical painless syringe needle in order to solve the above problems.
本发明通过以下技术方案来实现上述目的:The present invention achieves the above object through the following technical solutions:
本发明所述注射器针头的管壁表面设置有不规则表面,所述不规则表面具体为凹坑型、锯齿型和波纹型,所述凹坑型的管壁表面均匀分布多个凹坑,所述锯齿型的管壁表面分段均匀设置多组锯齿段,所述波纹型的管壁为整条针管呈波纹型。The surface of the tube wall of the syringe needle of the present invention is provided with an irregular surface, and the irregular surface is specifically a pit type, a zigzag type, and a corrugated type, and a plurality of pits are evenly distributed on the tube wall surface of the pit type, so that The sawtooth-shaped tube wall surface is uniformly provided with multiple groups of sawtooth segments, and the corrugated tube wall is corrugated for the entire needle tube.
具体地,所述凹坑型的管壁上均匀分布有25-30个凹坑。所述波纹型的管壁,其中,波纹的深度为0.05mm,两波纹之间的间距为0.75mm,波纹的宽度为0.1mm。所述锯齿型的管壁,其中,锯齿的深度为0.05mm,两锯齿之间的间距为0.75mm,锯齿的宽度为0.1mm。Specifically, 25-30 pits are evenly distributed on the pit-shaped pipe wall. In the corrugated pipe wall, the depth of the corrugations is 0.05 mm, the distance between two corrugations is 0.75 mm, and the width of the corrugations is 0.1 mm. In the sawtooth-shaped pipe wall, the depth of the sawtooth is 0.05 mm, the distance between two sawtooth is 0.75 mm, and the width of the sawtooth is 0.1 mm.
本发明的有益效果在于:The beneficial effects of the present invention are:
本发明是一种新型医用无痛注射器针头,与现有技术相比,本发明通过蚊子仿生技术研制,和注射针头平滑的片面相比,改进后的注射器和皮肤组织接触的面积较小,减少了对神经的刺激,使注射产生的疼痛感大大降低,进而提高其使用的便捷程度。关键问题在于如何将针头做成锯齿状微米结构,减少对皮肤的摩擦,同时尽可能实现资源再利用。具有推广应用的价值。The invention is a new type of medical painless syringe needle. Compared with the prior art, the invention is developed through mosquito bionic technology. Compared with the smooth one-sided surface of the injection needle, the contact area between the improved syringe and the skin tissue is smaller, reducing It greatly reduces the pain caused by injection and improves the convenience of its use. The key issue is how to make the needles into a jagged micron structure to reduce friction on the skin while reusing resources as much as possible. It has the value of promotion and application.
附图说明Description of drawings
图1是本发明的凹坑型的针管结构剖视图;Fig. 1 is the sectional view of the needle tube structure of dimple type of the present invention;
图2是本发明的锯齿型的针管结构剖视图;Fig. 2 is a cross-sectional view of the sawtooth needle tube structure of the present invention;
图3是本发明的波纹型的针管结构剖视图。Fig. 3 is a sectional view of the corrugated needle tube structure of the present invention.
图中:1-管壁、2-凹坑型、3-锯齿型、4-波纹型。In the figure: 1-pipe wall, 2-pit type, 3-serrated type, 4-corrugated type.
具体实施方式detailed description
下面结合附图对本发明作进一步说明:The present invention will be further described below in conjunction with accompanying drawing:
如图1至图3所示:本发明所述注射器针头的管壁1表面设置有不规则表面,所述不规则表面具体为凹坑型2、锯齿型3和波纹型4,所述凹坑型的管壁表面均匀分布多个凹坑,所述锯齿型的管壁表面分段均匀设置多组锯齿段,所述波纹型的管壁为整条针管呈波纹型。As shown in Figures 1 to 3: the surface of the tube wall 1 of the syringe needle of the present invention is provided with an irregular surface, and the irregular surface is specifically a pit type 2, a zigzag type 3 and a corrugated type 4, and the pits A plurality of pits are uniformly distributed on the surface of the tube wall of the zigzag type, multiple groups of sawtooth sections are evenly arranged on the surface of the zigzag tube wall, and the corrugated tube wall is corrugated for the entire needle tube.
具体地,所述凹坑型的管壁上均匀分布有25-30个凹坑。所述波纹型的管壁,其中,波纹的深度为0.05mm,两波纹之间的间距为0.75mm,波纹的宽度为0.1mm。所述锯齿型的管壁,其中,锯齿的深度为0.05mm,两锯齿之间的间距为0.75mm,锯齿的宽度为0.1mm。Specifically, 25-30 pits are evenly distributed on the pit-shaped pipe wall. In the corrugated pipe wall, the depth of the corrugations is 0.05 mm, the distance between two corrugations is 0.75 mm, and the width of the corrugations is 0.1 mm. In the sawtooth-shaped pipe wall, the depth of the sawtooth is 0.05 mm, the distance between two sawtooth is 0.75 mm, and the width of the sawtooth is 0.1 mm.
蚊子口针的锯齿形结构是倒刺形结构,由于其本身具有一定的柔性,在刺入和拔出时的方向是可以改变的,而注射针头时刚性结构,其上的非光滑结构无法改变,因此,为了使实验结果更加全面,要进行针阻力和拔针阻力的实验分析,The zigzag structure of the mosquito stylet is a barbed structure. Because of its flexibility, the direction of insertion and extraction can be changed, while the injection needle is a rigid structure, and the non-smooth structure on it cannot be changed. , therefore, in order to make the experimental results more comprehensive, the experimental analysis of the needle resistance and the needle withdrawal resistance should be carried out,
本发明主要分析研究了影响生物减阻的因素,如生物表面润滑减阻,电减阻,表面疏水性减阻,表面非光滑减阻技术,表面柔性减阻技术,还有蚊子,蝉解剖特点,口径的基本结构和口径结构特征的提取,蚊子口器的结构特点是在这个喙背部的唇槽内包藏有上唇、一对上颚、一对下颚和舌特化而成的6根细长的口针。上内唇、舌、上颚与下颚相合成而成刺割器官,下唇仅是保护这些刺割器官的。上颚前端细而光滑,末端较宽如刀状,内侧生有细的锯齿25~30个,是吸血时首先用以切割皮肤的工具。基于这一原理,从仿生学角度出发,模仿蚊子,蝉等昆虫刺吸式口器动物的非光滑形态和结构特点来设计针头。根据蚊子,蝉的口径特点做出了三种管型分别是凹坑形,波纹形,锯齿形,并做了正交试验。具有波纹形仿生结构形态的注射针头减阻率最佳,当深度为0.05mm,间距为0.75m m,宽度为0.1m m时,减阻率为44.5%。我们最终采用了波纹形仿生结构研究具有明显减阻效果的原因是仿生形态使针壁与皮肤组织细胞接触时存在间隙,减小接触面积,使摩擦阻力减小。The present invention mainly analyzes and studies factors affecting biological drag reduction, such as biological surface lubrication drag reduction, electrical drag reduction, surface hydrophobic drag reduction, surface non-smooth drag reduction technology, surface flexible drag reduction technology, and mosquitoes and cicada anatomical characteristics , the basic structure of the caliber and the extraction of the structural characteristics of the caliber. The structural feature of the mosquito mouthparts is that the upper lip, a pair of upper jaws, a pair of lower jaws and tongue are specially formed in the labial groove on the back of the beak. stylet. The upper inner lip, tongue, upper jaw and lower jaw are combined to form the piercing organs, and the lower lip is only to protect these piercing organs. The front end of the upper jaw is thin and smooth, and the end is wider like a knife. There are 25 to 30 thin serrations on the inner side, which are the first tools used to cut the skin when sucking blood. Based on this principle, from the perspective of bionics, the needle is designed by imitating the non-smooth shape and structural characteristics of mosquitoes, cicadas and other insect piercing and sucking mouthparts. According to the caliber characteristics of mosquitoes and cicadas, three tube shapes were made, namely pit shape, corrugated shape and zigzag shape, and an orthogonal test was done. The injection needle with corrugated bionic structure has the best drag reduction rate. When the depth is 0.05mm, the spacing is 0.75mm, and the width is 0.1mm, the drag reduction rate is 44.5%. We finally adopted the corrugated bionic structure to study the obvious drag reduction effect. The reason is that there is a gap when the bionic shape makes the needle wall contact with the skin tissue cells, which reduces the contact area and reduces the frictional resistance.
以上显示和描述了本发明的基本原理和主要特征及本发明的优点。本行业的技术人员应该了解,本发明不受上述实施例的限制,上述实施例和说明书中描述的只是说明本发明的原理,在不脱离本发明精神和范围的前提下,本发明还会有各种变化和改进,这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围由所附的权利要求书及其等效物界定。The basic principles and main features of the present invention and the advantages of the present invention have been shown and described above. Those skilled in the industry should understand that the present invention is not limited by the above-mentioned embodiments. What are described in the above-mentioned embodiments and the description only illustrate the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will also have Variations and improvements are possible, which fall within the scope of the claimed invention. The protection scope of the present invention is defined by the appended claims and their equivalents.
Claims (4)
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Cited By (3)
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CN106730308A (en) * | 2016-12-08 | 2017-05-31 | 卢欣旸 | A kind of fibroin albumen micropin of imitative mosquito mouthpart and preparation method thereof |
CN108478908A (en) * | 2018-05-07 | 2018-09-04 | 吉林大学 | A kind of bionical painless syringe syringe needle |
CN113198105A (en) * | 2021-06-03 | 2021-08-03 | 烟台大学 | Random bionic micro-texture brain deep stimulation sleeve electrode with roughened surface |
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CN1765428A (en) * | 2005-11-18 | 2006-05-03 | 吉林大学 | painless syringe |
CN200984221Y (en) * | 2006-12-20 | 2007-12-05 | 梁忠海 | Double-edge sawtooth type affusing needle |
CN203436636U (en) * | 2013-01-19 | 2014-02-19 | 吉林大学 | Syringe needle with bionic-form point |
CN104971406A (en) * | 2015-05-22 | 2015-10-14 | 南京农业大学 | Medical needle with micro-reflector structure on surface and preparation method thereof |
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