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CN106036894A - Food composition for improving chemotherapeutic symptoms of cancer patients and preparation method of food composition - Google Patents

Food composition for improving chemotherapeutic symptoms of cancer patients and preparation method of food composition Download PDF

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Publication number
CN106036894A
CN106036894A CN201610528396.6A CN201610528396A CN106036894A CN 106036894 A CN106036894 A CN 106036894A CN 201610528396 A CN201610528396 A CN 201610528396A CN 106036894 A CN106036894 A CN 106036894A
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powder
extract
water
filtrate
dried
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CN106036894B (en
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黄德欢
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GUANGZHOU KNOCKIM PHARMACY CO Ltd
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GUANGZHOU KNOCKIM PHARMACY CO Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention provides a food composition for improving chemotherapeutic symptoms of cancer patients and a preparation method of the food composition. The food composition is prepared from Rhizoma Dioscoreae powder, black bean powder, oat powder, whey protein powder, Fructus Lycii extract, aloe extract, Radix Sophorae Flavescentis extract and Fructus Jujubae extract. The food composition is effective in alleviation and improvement of symptoms such as dizziness, insomnia, nausea and vomiting after chemotherapy and is rich in aroma, delicate in taste, slightly sweet and tasty, and technical simplicity in preparation, low cost and quality controllability are realized.

Description

A kind of food compositions improving chemotherapy symptom and preparation method thereof
Technical field
The invention belongs to field of health care food, particularly relate to one and can improve Nausea and vomiting etc. after chemotherapy Food compositions of symptom and preparation method thereof.
Background technology
Cancer is a modal class in malignant tumor, is that the cell of local organization exists under various tumorigenesis factor effects The paraplasm losing normal adjusting and controlling growth on gene level and cause and differentiation, be serious threat human life and health Major disease.At present, the treatment of malignant tumor is based on comprehensive therapeutic plan, and chemotherapy (abbreviation chemotherapy) is in Comprehensive Treatment side Case occupies critical role.The most postoperative, chemotherapy is all widely used, by using chemotherapeutic drug Thing, can reach to kill the therapeutic purposes of cancerous cell.But, chemotherapeutics would generally spread all over the biggest of whole body along with blood circulation , easily there is multiple toxic and side effects in partial organ and tissue, including:Digestive system side effect: cancer patient holds after chemotherapy Nausea,vomiting,diarrhea and constipation easily occur;Bone marrow depression: chemotherapy can cause internal leukocyte and thrombocytopenia;De- Send out: part chemotherapeutics can cause alopecia;Hepatic and renal function damages: part chemotherapeutics can cause the hepatic and renal function of patient to damage Wound.
For cancer patient, the symptom such as nausea,vomiting,diarrhea and constipation easily occurs after chemotherapy, thus appetite is not Shake, and patient can be caused huge stress, cause patient's body undernutrition, resistance to decline, be unfavorable for chemotherapy The performance of effect and the rehabilitation of body.It is known that many Chinese medicines have certain antitumor action, some Chinese medicine extract and Compound preparation also shows that stronger chemotherapy of tumors assosting effect.Chinese medicine is thought, is often accompanied by gas consumption impairment of YIN in chemotherapy process, Taste are impaired waits disease, by YIN nourishing, QI invigorating, spleen invigorating, can reach that QI and blood regulating, internal organs be dirty and negative and positive, make QI and blood grow, with correction QI consumed the moon wound in chemotherapy process, makes impaired taste be revised.The Chinese medicine being proved to have chemotherapy assosting effect at present includes The most several classes:The activity extract of deficiency tonifying kind, such as Radix Ginseng, Ganoderma etc., SHENQI FUZHENG ZHUSHEYE, decoction of four noble drugs etc.;Live Blood and dissolving stasis class, the such as activity extract of Radix Notoginseng, Radix Salviae Miltiorrhizae, Rhizoma Curcumae Longae, Radix Curcumae etc.;Heat clearing away class, such as Radix Sophorae Flavescentis, Herba Artemisiae Annuae, Radix Isatidis, The activity extract of Herba Portulacae Grandiflorae etc.;The activity extract of promoting diuresis to eliminate damp pathogen class, such as Radix Stephaniae Tetrandrae.Study mechanism shows, middle medical instrument The effect having adjuvant chemotherapy is mainly based upon the immunologic function improving body, hemopoietic function protecting, protection lung, liver, kidney, bladder etc. Important organ etc..
But, owing to patients undergoing chemotherapy is by physiology and the dual-pressure of psychology, often there is no appetite, and part be postoperative swollen Tumor patient has the difficulty chewed, swallow, digest and assimilate, and major part Chinese medicine odor is the best, and bitterness is strong, therefore can be to Chinese medicine There is certain repellency, thus affect the drug compliance of patient.In the Chinese medicine having now found that, have in many integration of edible and medicinal herbs Medicine, they not only have certain pharmacologically active, and are also the common food on people's dining table.
The present invention is by selecting to improve the diseases such as leukopenia that carcinosis radiotherapy and chemotherapy causes, giddy, insomnia, nausea and vomiting The Chinese medicine of integration of edible and medicinal herbs, coordinate basal nutrient element, and utilize fragrance and the taste of food materials itself, improve health food Mouthfeel, has given play to the good effect improving chemotherapy symptom.
Summary of the invention
In order to overcome technical problem of the prior art, it is bad that the present invention is that cancer patient provides after one improves chemotherapy The health food of symptom, this food can not only meet cancer patient's need to the basic nutrition element such as carbohydrate, protein Ask, and also combine leukopenia that cancer chemotherapy is caused, giddy, insomnia, the disease such as bad habit vomiting have improvement result The Chinese medicine material of integration of edible and medicinal herbs, and delicate mouthfeel, taste are excellent, are very suitable for cancer patient edible after chemotherapy.
For reaching above-mentioned technique effect, the present invention is to be implemented by following technical scheme.
On the one hand, the invention provides a kind of food compositions for improving chemotherapy symptom, its feature exists In being carried by Rhizoma Dioscoreae powder, black bean powder, oatmeal, lactalbumin powder, wolfberry fruit extract, Germinatus Phragmitis extract, Radix Sophorae Flavescentis extract and Fructus Jujubae Take thing composition.
In the food compositions of the present invention, Rhizoma Dioscoreae, Semen sojae atricolor, Fructus Lycii, Germinatus Phragmitis and Fructus Jujubae are all the materials of integration of edible and medicinal herbs.Its In, Rhizoma Dioscoreae is Dioscoreaceae plant Rhizoma Dioscoreae dry rhizome, has and nourishes strong, aid digestion, to hold back sweating due to debility, antidiarrheal effect, Rhizoma Dioscoreae block Stem, rich in polysaccharide, can stimulate and regulate human immune system, and the health care medicine therefore often making to strengthen immunocompetence uses.Semen sojae atricolor is The black seeds of legume soybean, containing multiple nutritional components such as protein, fat, vitamin, trace element, has again simultaneously There is various bioactivators, such as studies on black soybean pigment, Semen sojae atricolor polysaccharide and isoflavone etc., there is effect of the kidney invigorating, strengthening the spleen, to flatulence, Constipation has obvious curative effects.Fructus Lycii is the mature fruit of matrimony vine of solanaceae plant, containing lycium barbarum polysaccharide, glycine betaine and wolfberry pigment etc., There is the effects such as the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, observe Fructus Lycii to cancerous cell by the method for cell injuring model Biological effect, it was demonstrated that people's adenocarcinoma of stomach, cervical cancer cell are all had obvious inhibiting effect, Fructus Lycii combination with radiotherapeutic to have substantially by Fructus Lycii Radiation potentiation.Germinatus Phragmitis is Asparagaceae Asparagus (genus asparagus) herbaceos perennial, has invigorating the spleen and benefiting QI, YIN nourishing profit Dry effect, rich in proteins, multivitamin and the mineral such as calcium, phosphorus, there is better nutritivity and be worth, and contained Tianmen Winter amide has special physiological action and enhancing immunity effect to human body, and it is different that contained histone can efficiently control cell Being frequently grown, make cell normalization, research shows, Germinatus Phragmitis all has obvious preventive and therapeutic effect to various cancers, simultaneously can also alleviating Learn Drug therapy and radiocurable side effect.Fructus Jujubae is the fruit of Rhamnaceae plant Fructus Jujubae, and vitamin content is the highest, has benefit Spleen, the effect nourishing blood, calming the nerves, pharmacological research finds, Fructus Jujubae can promote the generation of leukocyte, reduces serum cholesterol, improves blood Pure albumen, the liver protecting, possibly together with anticancer in Fructus Jujubae, the cancerous cell material to normal cell turnover even can be made.
Possibly together with Radix Sophorae Flavescentis extract in the food compositions of the present invention.Radix Sophorae Flavescentis is the dry root of leguminous plant Radix Sophorae Flavescentis, has Heat clearing and damp drying, effect of parasite killing diuresis, owing to rich in matrine, oxymatrine, sophocarpine, can be effectively improved exempting from of body Epidemic disease power, and there is certain active anticancer.Although Radix Sophorae Flavescentis has been shown to have preferable anticancer effect, and can be used for improvement and put Untoward reaction after treatment, but, Radix Sophorae Flavescentis has the denseest bitterness, therefore, it is difficult to directly eat.The present invention is by wearing into Rhizoma Dioscoreae Powder, and utilize zymolysis technique to obtain the Fructus Jujubae extract that dissolution velocity is fast, utilize Rhizoma Dioscoreae and the natural scents of Fructus Jujubae and sweet taste to cover The bitterness of lid Radix Sophorae Flavescentis, effectively improves the mouthfeel of food composition.Meanwhile, by adding oatmeal and lactalbumin powder, for changing Treat patient and provide abundant Plant fiber, vitamin, albumen and trace element.
As preferred technical scheme, the food compositions of the present invention is by Rhizoma Dioscoreae powder 10-30 weight portion, black bean powder 10-20 Weight portion, oatmeal 8-15 weight portion, lactalbumin powder 10-20 weight portion, wolfberry fruit extract 15-25 weight portion, Germinatus Phragmitis are extracted Thing 10-20 weight portion, Radix Sophorae Flavescentis extract 5-15 weight portion and Fructus Jujubae extract 5-12 weight portion composition.
In addition to fragrance and taste, the granule size of food materials powder also can affect local flavor and the mouthfeel of food composition.This Inventor finds, when the powder particle in food composition of the present invention is more than 100 mesh, can make coarse mouthfeel, have slag particle sense; When powder particle is less than 300 mesh, powder is difficult to stir evenly after meeting water, and easily lumps in storage process, the bag to food Dress and shelf appeal are higher;When powder particle is at 100-300 mesh, not only give off a strong fragrance, delicate mouthfeel, and meet water and easily divide Dissipate, excellent storage stability.Therefore, it is further preferred that the fine powder that Rhizoma Dioscoreae powder, black bean powder and oatmeal were 100-300 mesh sieve.
In the present invention in the food compositions improving chemotherapy symptom, Fructus Lycii, Germinatus Phragmitis, Radix Sophorae Flavescentis and Fructus Jujubae are equal Presented in extract.Further, extract is preferably prepared by following method.
The preparation method of wolfberry fruit extract is: wears into screened stock after new fresh fructus lycii or dry wolfberry are added suitable quantity of water, is subsequently adding The 40-60% ethanol solution of 8-12 times of volume, stirs, the microwave extraction 20-60 second under the power of 400-600W, filters, Filtrate is standby, and filtering residue adds the water of 8-10 times of volume, and is heated to 60-80 DEG C of extraction 1-3 hour, filters, merging filtrate, spraying It is dried to powder, pulverized 100-200 mesh sieve, and to obtain final product;
The preparation method of Germinatus Phragmitis extract is: wears into screened stock after new fresh asparagus cutting, is subsequently adding the water of 6-10 times of volume, stirs Mix uniformly, be heated to 80-110 DEG C and extract 30-60 minute, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh Sieve, to obtain final product;
The preparation method of Radix Sophorae Flavescentis extract is: Radix Sophorae Flavescentis powder is broken into powder, and the 40-60% alcohol reflux adding 6-8 times of volume carries Taking 1.5-3 hour, filter, decompression filtrate recycling ethanol to without alcohol taste, is subsequently adding the water of 8-10 times of volume, and mix homogeneously is quiet Putting 12-24 hour, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh sieve, and to obtain final product;
The preparation method of Fructus Jujubae extract is: by broken for extra dry red wine date powder, adds suitable quantity of water and wears into screened stock, is subsequently adding 2-8 times of volume Water and the pectin compound enzyme of 260-300 μ L/g carry out enzymolysis 0.5-1.5 hour, then under the power of 400-600W, microwave carries Take the 30-60 second, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh sieve, and to obtain final product.
On the other hand, present invention also offers described for improving the preparation of the food compositions of chemotherapy symptom Method, it is characterised in that comprise the steps:
1), Rhizoma Dioscoreae powder, black bean powder and oatmeal are dried to water content 8%, and be ground into 100-300 with jet mill The fine powder of mesh sieve;
2), new fresh fructus lycii or dry wolfberry are added suitable quantity of water after wear into screened stock, the 40-60% ethanol being subsequently adding 8-12 times of volume is molten Liquid, stirs, the microwave extraction 20-60 second under the power of 400-600W, filters, and filtrate is standby, and filtering residue adds 8-10 times of body Long-pending water, and it is heated to 60-80 DEG C of extraction 1-3 hour, filter, merging filtrate, be spray-dried to powder, pulverized 100-200 Mesh sieve, obtains wolfberry fruit extract standby;
3), after new fresh asparagus cutting, wear into screened stock, be subsequently adding the water of 6-10 times of volume, stir, be heated to 80-110 DEG C extract 30-60 minute, filter, by filtrate be spray-dried to powder, pulverized 100-200 mesh sieve, obtained Germinatus Phragmitis extract standby;
4), by Radix Sophorae Flavescentis powder it is broken into powder, the 40-60% alcohol reflux of 6-8 times of volume of addition 1.5-3 hour, filters, filtrate Decompression recycling ethanol, to without alcohol taste, is subsequently adding the water of 8-10 times of volume, mix homogeneously, stands 12-24 hour, filters, filtrate It is spray-dried to powder, pulverized 100-200 mesh sieve, and obtained Radix Sophorae Flavescentis extract standby;
5), by broken for extra dry red wine date powder, add suitable quantity of water and wear into screened stock, be subsequently adding water and the fruit of 260-300 μ L/g of 2-8 times of volume Glue compound enzyme carries out enzymolysis 0.5-1.5 hour, then the microwave extraction 30-60 second under the power of 400-600W, filters, by filtrate It is spray-dried to powder, pulverized 100-200 mesh sieve, and obtained Fructus Jujubae extract standby;
6), first by Radix Sophorae Flavescentis extract mix homogeneously with Fructus Jujubae extract, be subsequently adding wolfberry fruit extract and Germinatus Phragmitis extract, mixing Uniformly, it is eventually adding Rhizoma Dioscoreae powder, black bean powder, oatmeal and lactalbumin powder, mix homogeneously, splitting, sterilizing, vacuum seal, bag Dress, to obtain final product.
In preparation process, the present inventor is found surprisingly that, is mixed the most in batches by above-mentioned raw materials Close, can effectively cover the bitterness of Radix Sophorae Flavescentis extract, it may be possible to because the viscosity of Fructus Jujubae extract is relatively big, first by Radix Sophorae Flavescentis extract Mix with Fructus Jujubae extract, the fine powder of Fructus Jujubae extract can be made to stick to the surface of Radix Sophorae Flavescentis extract powder particle, make When must meet water-dispersible dissolving, in the microenvironment being formed about there is sweet taste of Radix Sophorae Flavescentis extract granule.
Compared with prior art, the present invention has a following good effect:
, the present invention food composition for the impaired principle of taste after chemotherapy, will have the kidney invigorating, strengthening the spleen effect Rhizoma Dioscoreae, Semen sojae atricolor, Fructus Lycii, Germinatus Phragmitis, the material of the integration of edible and medicinal herbs such as Fructus Jujubae, in conjunction with heat clearing away based chemotherapy Chinese herbs Radix Sophorae Flavescentis, jointly rise To YIN nourishing, QI invigorating, the effect of spleen invigorating, effectively alleviate and improve the symptoms such as the giddy after chemotherapy, insomnia, nausea and vomiting;Simultaneously Add oatmeal and lactalbumin powder, provide abundant Plant fiber, vitamin, albumen and trace element for patients undergoing chemotherapy, Enhance the nutrition of food.
, the present invention utilize Rhizoma Dioscoreae and the natural scents of Fructus Jujubae and sweet taste to cover the bitterness of Radix Sophorae Flavescentis, and by controlling food materials Powder size and adjust order by merging, it is thus achieved that give off a strong fragrance, delicate mouthfeel, micro-sweet good to eat health food.
, the present composition preparation technology simple, low cost, quality controllable, be suitable for the demand of industrialized great production.
Detailed description of the invention
Illustrated further the description present invention by following example, and limits the present invention never in any form, without departing substantially from On the premise of the technical solution of the present invention, what those of ordinary skill in the art made for the present invention easily realized any changes Within dynamic or change falls within scope of the presently claimed invention.
Embodiment 1: the preparation of the present composition
Formula:
Rhizoma Dioscoreae powder 20 weight portion, black bean powder 15 weight portion, oatmeal 10 weight portion, lactalbumin powder 12 weight portion, Fructus Lycii are extracted Thing 18 weight portion, Germinatus Phragmitis extract 12 weight portion, Radix Sophorae Flavescentis extract 12 weight portion and Fructus Jujubae extract 10 weight portion composition
Preparation method:
1), Rhizoma Dioscoreae powder, black bean powder and oatmeal are dried to water content 8%, and be ground into 300 mesh sieves with jet mill Fine powder;
2), new fresh fructus lycii or dry wolfberry are added suitable quantity of water after wear into screened stock, be subsequently adding 60% ethanol solution of 10 times of volumes, stir Mix uniformly, microwave extraction 30 seconds under the power of 500W, filter, filtrate is standby, and filtering residue adds the water of 8 times of volumes, and is heated to 80 DEG C are extracted 1 hour, filter, merging filtrate, are spray-dried to powder, pulverize 200 mesh sieves, and obtained wolfberry fruit extract standby;
3), after new fresh asparagus cutting, wear into screened stock, be subsequently adding the water of 8 times of volumes, stir, be heated to 90 DEG C and extract 30 Minute, filter, filtrate is spray-dried to powder, pulverized 200 mesh sieves, and obtained Germinatus Phragmitis extract standby;
4), by Radix Sophorae Flavescentis powder being broken into powder, 60% alcohol reflux of 8 times of volumes of addition 2 hours, filter, filtrate decompression reclaims Ethanol, to without alcohol taste, is subsequently adding the water of 8 times of volumes, mix homogeneously, stands 20 hours, filters, and filtrate is spray-dried to powder, Pulverize 200 mesh sieves, obtain Radix Sophorae Flavescentis extract standby;
5), by broken for extra dry red wine date powder, adding suitable quantity of water and wear into screened stock, the pectin of the water and 280 μ L/g that are subsequently adding 3 times of volumes is combined Enzyme carries out enzymolysis 1.0 hours, then microwave extraction 30 seconds under the power of 500W, filters, and is spray-dried filtrate to powder, powder Broken mistake 200 mesh sieve, obtains Fructus Jujubae extract standby;
6), first by Radix Sophorae Flavescentis extract mix homogeneously with Fructus Jujubae extract, be subsequently adding wolfberry fruit extract and Germinatus Phragmitis extract, mixing Uniformly, it is eventually adding Rhizoma Dioscoreae powder, black bean powder, oatmeal and lactalbumin powder, mix homogeneously, splitting, sterilizing, vacuum seal, bag Dress, obtains solid beverage.
Embodiment 2: the preparation of the present composition
Formula:
Rhizoma Dioscoreae powder 10 weight portion, black bean powder 15 weight portion, oatmeal 8 weight portion, lactalbumin powder 18 weight portion, wolfberry fruit extract 20 weight portions, Germinatus Phragmitis extract 10 weight portion, Radix Sophorae Flavescentis extract 10 weight portion and Fructus Jujubae extract 8 weight portion composition
Preparation method:
1), Rhizoma Dioscoreae powder, black bean powder and oatmeal are dried to water content 8%, and be ground into 100 mesh sieves with jet mill Fine powder;
2), new fresh fructus lycii or dry wolfberry are added suitable quantity of water after wear into screened stock, be subsequently adding 60% ethanol solution of 12 times of volumes, stir Mix uniformly, microwave extraction 60 seconds under the power of 400, filter, filtrate is standby, and filtering residue adds the water of 8 times of volumes, and is heated to 60 DEG C extract 3 hours, filter, merging filtrate, be spray-dried to powder, pulverized 100 mesh sieves, obtained wolfberry fruit extract standby;
3), after new fresh asparagus cutting, wear into screened stock, be subsequently adding the water of 6 times of volumes, stir, be heated to 80 DEG C and extract 40 Minute, filter, filtrate is spray-dried to powder, pulverized 100 mesh sieves, and obtained Germinatus Phragmitis extract standby;
4), by Radix Sophorae Flavescentis powder being broken into powder, 40% alcohol reflux of 8 times of volumes of addition 1.5 hours, filter, filtrate decompression is returned Receipts ethanol, to without alcohol taste, is subsequently adding the water of 10 times of volumes, mix homogeneously, stands 15 hours, filters, and filtrate is spray-dried to powder End, pulverized 100 mesh sieves, obtained Radix Sophorae Flavescentis extract standby;
5), by broken for extra dry red wine date powder, adding suitable quantity of water and wear into screened stock, the pectin of the water and 265 μ L/g that are subsequently adding 5 times of volumes is combined Enzyme carries out enzymolysis 1.5 hours, then microwave extraction 30 seconds under the power of 400W, filters, and is spray-dried filtrate to powder, powder Broken mistake 100 mesh sieve, obtains Fructus Jujubae extract standby;
6), first by Radix Sophorae Flavescentis extract mix homogeneously with Fructus Jujubae extract, be subsequently adding wolfberry fruit extract and Germinatus Phragmitis extract, mixing Uniformly, it is eventually adding Rhizoma Dioscoreae powder, black bean powder, oatmeal and lactalbumin powder, mix homogeneously, splitting, sterilizing, vacuum seal, bag Dress, obtains solid beverage.
Embodiment 3: the preparation of the present composition
Formula:
Rhizoma Dioscoreae powder 30 weight portion, black bean powder 15 weight portion, oatmeal 10 weight portion, lactalbumin powder 10 weight portion, Fructus Lycii are extracted Thing 15 weight portion, Germinatus Phragmitis extract 18 weight portion, Radix Sophorae Flavescentis extract 10 weight portion and Fructus Jujubae extract 12 weight portion composition
Preparation method:
1), Rhizoma Dioscoreae powder, black bean powder and oatmeal are dried to water content 8%, and be ground into 200 mesh sieves with jet mill Fine powder;
2), new fresh fructus lycii or dry wolfberry are added suitable quantity of water after wear into screened stock, be subsequently adding 50% ethanol solution of 10 times of volumes, stir Mix uniformly, microwave extraction 40 seconds under the power of 500W, filter, filtrate is standby, and filtering residue adds the water of 8 times of volumes, and is heated to 80 DEG C are extracted 2 hours, filter, merging filtrate, are spray-dried to powder, pulverize 200 mesh sieves, and obtained wolfberry fruit extract standby;
3), after new fresh asparagus cutting, wear into screened stock, be subsequently adding the water of 6 times of volumes, stir, be heated to 100 DEG C of extractions 60 minutes, filter, filtrate is spray-dried to powder, pulverized 200 mesh sieves, and obtained Germinatus Phragmitis extract standby;
4), by Radix Sophorae Flavescentis powder being broken into powder, 40% alcohol reflux of 8 times of volumes of addition 2 hours, filter, filtrate decompression reclaims Ethanol, to without alcohol taste, is subsequently adding the water of 10 times of volumes, mix homogeneously, stands 12 hours, filters, and filtrate is spray-dried to powder End, pulverized 200 mesh sieves, obtained Radix Sophorae Flavescentis extract standby;
5), by broken for extra dry red wine date powder, adding suitable quantity of water and wear into screened stock, the pectin of the water and 300 μ L/g that are subsequently adding 4 times of volumes is combined Enzyme carries out enzymolysis 0.8 hour, then microwave extraction 50 seconds under the power of 500W, filters, and is spray-dried filtrate to powder, powder Broken mistake 200 mesh sieve, obtains Fructus Jujubae extract standby;
6), first by Radix Sophorae Flavescentis extract mix homogeneously with Fructus Jujubae extract, be subsequently adding wolfberry fruit extract and Germinatus Phragmitis extract, mixing Uniformly, it is eventually adding Rhizoma Dioscoreae powder, black bean powder, oatmeal and lactalbumin powder, mix homogeneously, splitting, sterilizing, vacuum seal, bag Dress, obtains solid beverage.
Embodiment 4: on the impact of symptom after chemotherapy
One, subjects
Selecting 80 example pathological sections in certain hospital admission personnel and turn out to be the patient of cancer, the age is 26-53 year, wherein male 49, women 31.All patients all goes postoperative standard adjuvant chemotherapy CMF or CAF/CTF/CEF scheme.
Two, test specimen
The solid beverage prepared according to the embodiment of the present application 1.
Three, test method and result
80 example subjects, after chemotherapy, eat the solid beverage prepared according to the embodiment of the present application 1, three times a day, often Secondary 40 grams, warm boiled water.After two months chemotherapy symptom (including Nausea and vomiting, constipation, insomnia) is paid a return visit.Result is shown in Table 1.
Table 1 eats the present composition impact on chemotherapy symptom
Result shows, after the solid beverage of the edible present invention, the chemotherapy symptom of cancer patient have and more significantly improve (P < 0.05 or P < 0.01).
Embodiment 5: taste appraisal
One, group is evaluated
Randomly choose 30 health volunteers and form taste appraisal group, wherein male 15, women 15.
Two, test specimen
Of the present invention group: the solid beverage prepared according to the embodiment of the present application 1.
Matched group 1: the solid beverage prepared according to the embodiment of the present application 1, difference is to replace with Radix Glycyrrhizae extract Fructus Jujubae extract.
Matched group 2: the solid beverage prepared according to the embodiment of the present application 1, difference is only 100-200 mesh sieve.
Matched group 3: the solid beverage prepared according to the embodiment of the present application 1, difference is all material powders one Play mixing.
Three, test method
Respectively the solid beverage of of the present invention group, matched group 1-3 is tasted, before trial test by 30 members of taste appraisal group Solid beverage is disperseed by appropriate warm water, with clear water gargles between tasting every time.
Four, mouthfeel evaluation criterion
1, fragrance: British plain spirits 0;Savory 1.
2, sugariness: more bitter 0;Sweeter 1.
3, quality: coarse mouthfeel 0;Delicate mouthfeel 1.
Five, result
Taste appraisal group is shown in Table 2 to the appraisal result of of the present invention group, the solid beverage of matched group 1-3.
The taste scoring of of the present invention group of table 2 and matched group
Group Fragrance Sugariness Quality Overall score
Of the present invention group 25 27 29 81
Matched group 1 14 13 28 55
Matched group 2 26 25 21 72
Matched group 3 23 19 23 65
Result shows, the solid beverage of the present invention is matched group 1-3 to be substantially better than in mouthfeel, is therefore easier to by cancer chemotherapy Patient accepts.

Claims (5)

1. the food compositions being used for improving chemotherapy symptom, it is characterised in that by Rhizoma Dioscoreae powder, black bean powder, Herba bromi japonici Powder, lactalbumin powder, wolfberry fruit extract, Germinatus Phragmitis extract, Radix Sophorae Flavescentis extract and Fructus Jujubae extract composition.
2. the food compositions for improving chemotherapy symptom as claimed in claim 1, it is characterised in that by Rhizoma Dioscoreae Powder 10-30 weight portion, black bean powder 10-20 weight portion, oatmeal 8-15 weight portion, lactalbumin powder 10-20 weight portion, Fructus Lycii carry Take thing 15-25 weight portion, Germinatus Phragmitis extract 10-20 weight portion, Radix Sophorae Flavescentis extract 10-18 weight portion and Fructus Jujubae extract 5-12 weight Amount part composition.
3. the food compositions for improving chemotherapy symptom as claimed in claim 1 or 2, it is characterised in that Rhizoma Dioscoreae Powder, black bean powder and oatmeal were the fine powder of 100-300 mesh sieve.
4. the food compositions for improving chemotherapy symptom as claimed in claim 4, it is characterised in that:
The preparation method of wolfberry fruit extract is: wears into screened stock after new fresh fructus lycii or dry wolfberry are added suitable quantity of water, is subsequently adding 8-12 The 40-60% ethanol solution of times volume, stirs, the microwave extraction 20-60 second under the power of 400-600W, filters, filtrate Standby, filtering residue adds the water of 8-10 times of volume, and is heated to 60-80 DEG C of extraction 1-3 hour, filters, merging filtrate, is spray-dried To powder, pulverized 100-200 mesh sieve, to obtain final product;
The preparation method of Germinatus Phragmitis extract is: wears into screened stock after new fresh asparagus cutting, is subsequently adding the water of 6-10 times of volume, stirs Mix uniformly, be heated to 80-110 DEG C and extract 30-60 minute, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh Sieve, to obtain final product;
The preparation method of Radix Sophorae Flavescentis extract is: Radix Sophorae Flavescentis powder is broken into powder, and the 40-60% alcohol reflux adding 6-8 times of volume carries Taking 1.5-3 hour, filter, decompression filtrate recycling ethanol to without alcohol taste, is subsequently adding the water of 8-10 times of volume, and mix homogeneously is quiet Putting 12-24 hour, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh sieve, and to obtain final product;
The preparation method of Fructus Jujubae extract is: by broken for extra dry red wine date powder, adds suitable quantity of water and wears into screened stock, is subsequently adding 2-8 times of volume Water and the pectin compound enzyme of 260-300 μ L/g carry out enzymolysis 0.5-1.5 hour, then under the power of 400-600W, microwave carries Take the 30-60 second, filter, filtrate is spray-dried to powder, pulverized 100-200 mesh sieve, and to obtain final product.
5. the side of the food compositions for improving chemotherapy symptom prepared as described in one of claim 1-4 Method, it is characterised in that comprise the steps:
1), Rhizoma Dioscoreae powder, black bean powder and oatmeal are dried to water content 8%, and be ground into 100-300 with jet mill The fine powder of mesh sieve;
2), new fresh fructus lycii or dry wolfberry are added suitable quantity of water after wear into screened stock, the 40-60% ethanol being subsequently adding 8-12 times of volume is molten Liquid, stirs, the microwave extraction 20-60 second under the power of 400-600W, filters, and filtrate is standby, and filtering residue adds 8-10 times of body Long-pending water, and it is heated to 60-80 DEG C of extraction 1-3 hour, filter, merging filtrate, be spray-dried to powder, pulverized 100-200 Mesh sieve, obtains wolfberry fruit extract standby;
3), after new fresh asparagus cutting, wear into screened stock, be subsequently adding the water of 6-10 times of volume, stir, be heated to 80-110 DEG C extract 30-60 minute, filter, by filtrate be spray-dried to powder, pulverized 100-200 mesh sieve, obtained Germinatus Phragmitis extract standby;
4), by Radix Sophorae Flavescentis powder it is broken into powder, the 40-60% alcohol reflux of 6-8 times of volume of addition 1.5-3 hour, filters, filtrate Decompression recycling ethanol, to without alcohol taste, is subsequently adding the water of 8-10 times of volume, mix homogeneously, stands 12-24 hour, filters, filtrate It is spray-dried to powder, pulverized 100-200 mesh sieve, and obtained Radix Sophorae Flavescentis extract standby;
5), by broken for extra dry red wine date powder, add suitable quantity of water and wear into screened stock, be subsequently adding water and the fruit of 260-300 μ L/g of 2-8 times of volume Glue compound enzyme carries out enzymolysis 0.5-1.5 hour, then the microwave extraction 30-60 second under the power of 400-600W, filters, by filtrate It is spray-dried to powder, pulverized 100-200 mesh sieve, and obtained Fructus Jujubae extract standby;
6), first by Radix Sophorae Flavescentis extract mix homogeneously with Fructus Jujubae extract, be subsequently adding wolfberry fruit extract and Germinatus Phragmitis extract, mixing Uniformly, it is eventually adding Rhizoma Dioscoreae powder, black bean powder, oatmeal and lactalbumin powder, mix homogeneously, splitting, sterilizing, vacuum seal, bag Dress, to obtain final product.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108497277A (en) * 2018-01-27 2018-09-07 江西永昇制药股份有限公司 Compound fruit and vegetable anticancer nutritional meal formula
CN111743939A (en) * 2020-08-18 2020-10-09 晋中学院 A kind of ointment for relieving side effect of chemotherapy and its preparation method and use

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CN1194633A (en) * 1995-07-28 1998-09-30 凯米拉农业公司 Method for production of oligomethyleneurea
CN1194633C (en) * 2002-09-17 2005-03-30 刘洪涛 Multiple element nutritive powder
CN101623086A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color viscus-nourishing anticancer medicinal tea steamed bread and manufacturing method thereof
CN104413341A (en) * 2013-08-29 2015-03-18 青岛蓝色科技信息管理有限公司 Cereal porridge and making method thereof

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Publication number Priority date Publication date Assignee Title
CN1194633A (en) * 1995-07-28 1998-09-30 凯米拉农业公司 Method for production of oligomethyleneurea
CN1194633C (en) * 2002-09-17 2005-03-30 刘洪涛 Multiple element nutritive powder
CN101623086A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color viscus-nourishing anticancer medicinal tea steamed bread and manufacturing method thereof
CN104413341A (en) * 2013-08-29 2015-03-18 青岛蓝色科技信息管理有限公司 Cereal porridge and making method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108497277A (en) * 2018-01-27 2018-09-07 江西永昇制药股份有限公司 Compound fruit and vegetable anticancer nutritional meal formula
CN111743939A (en) * 2020-08-18 2020-10-09 晋中学院 A kind of ointment for relieving side effect of chemotherapy and its preparation method and use

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