CN105963216A - Plant composition and application thereof to preparation of oral care product - Google Patents
Plant composition and application thereof to preparation of oral care product Download PDFInfo
- Publication number
- CN105963216A CN105963216A CN201610537799.7A CN201610537799A CN105963216A CN 105963216 A CN105963216 A CN 105963216A CN 201610537799 A CN201610537799 A CN 201610537799A CN 105963216 A CN105963216 A CN 105963216A
- Authority
- CN
- China
- Prior art keywords
- oral care
- vegetable composition
- care product
- application
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 88
- 238000002360 preparation method Methods 0.000 title abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 28
- 229940034610 toothpaste Drugs 0.000 claims abstract description 27
- 239000000606 toothpaste Substances 0.000 claims abstract description 27
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 22
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 22
- 230000000694 effects Effects 0.000 claims abstract description 18
- 241000196324 Embryophyta Species 0.000 claims abstract description 6
- 235000013311 vegetables Nutrition 0.000 claims description 47
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 27
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 24
- 206010018276 Gingival bleeding Diseases 0.000 claims description 23
- 208000024283 Gingival haemorrhages Diseases 0.000 claims description 23
- 235000006784 Saussurea lappa Nutrition 0.000 claims description 20
- 239000002994 raw material Substances 0.000 claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 11
- 239000000419 plant extract Substances 0.000 claims description 10
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 9
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 9
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 9
- -1 polyoxyethylene Polymers 0.000 claims description 9
- 229940085605 saccharin sodium Drugs 0.000 claims description 9
- 239000000600 sorbitol Substances 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000004376 Sucralose Substances 0.000 claims description 8
- 235000019408 sucralose Nutrition 0.000 claims description 8
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 229920001223 polyethylene glycol Polymers 0.000 claims description 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- 239000000049 pigment Substances 0.000 claims description 6
- 239000003755 preservative agent Substances 0.000 claims description 6
- 230000002335 preservative effect Effects 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 239000000080 wetting agent Substances 0.000 claims description 6
- 108010011485 Aspartame Proteins 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 5
- 239000000605 aspartame Substances 0.000 claims description 5
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 5
- 235000010357 aspartame Nutrition 0.000 claims description 5
- 229960003438 aspartame Drugs 0.000 claims description 5
- 239000013538 functional additive Substances 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 5
- 229940013618 stevioside Drugs 0.000 claims description 5
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 5
- 235000019202 steviosides Nutrition 0.000 claims description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 4
- 229920001400 block copolymer Polymers 0.000 claims description 4
- 239000004359 castor oil Substances 0.000 claims description 4
- 235000019438 castor oil Nutrition 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 4
- 229940051841 polyoxyethylene ether Drugs 0.000 claims description 4
- 229920000056 polyoxyethylene ether Polymers 0.000 claims description 4
- 229920001451 polypropylene glycol Polymers 0.000 claims description 4
- 229920000136 polysorbate Polymers 0.000 claims description 4
- 239000000758 substrate Substances 0.000 claims description 4
- 239000000811 xylitol Substances 0.000 claims description 4
- 235000010447 xylitol Nutrition 0.000 claims description 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 4
- 229960002675 xylitol Drugs 0.000 claims description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
- 235000010216 calcium carbonate Nutrition 0.000 claims description 3
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 3
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 229950005875 laurilsulfate Drugs 0.000 claims description 3
- 230000002829 reductive effect Effects 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 2
- 229920002907 Guar gum Polymers 0.000 claims description 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 2
- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 claims description 2
- 239000000654 additive Substances 0.000 claims description 2
- 230000000996 additive effect Effects 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 229910021502 aluminium hydroxide Inorganic materials 0.000 claims description 2
- 229940024545 aluminum hydroxide Drugs 0.000 claims description 2
- 230000000975 bioactive effect Effects 0.000 claims description 2
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 claims description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 2
- 229940043256 calcium pyrophosphate Drugs 0.000 claims description 2
- 239000000679 carrageenan Substances 0.000 claims description 2
- 235000010418 carrageenan Nutrition 0.000 claims description 2
- 229920001525 carrageenan Polymers 0.000 claims description 2
- 229940113118 carrageenan Drugs 0.000 claims description 2
- 239000001913 cellulose Substances 0.000 claims description 2
- 235000010980 cellulose Nutrition 0.000 claims description 2
- 229920002678 cellulose Polymers 0.000 claims description 2
- 235000019821 dicalcium diphosphate Nutrition 0.000 claims description 2
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 2
- LRCFXGAMWKDGLA-UHFFFAOYSA-N dioxosilane;hydrate Chemical compound O.O=[Si]=O LRCFXGAMWKDGLA-UHFFFAOYSA-N 0.000 claims description 2
- 239000004088 foaming agent Substances 0.000 claims description 2
- 239000003292 glue Substances 0.000 claims description 2
- 239000000665 guar gum Substances 0.000 claims description 2
- 235000010417 guar gum Nutrition 0.000 claims description 2
- 229960002154 guar gum Drugs 0.000 claims description 2
- 239000013521 mastic Substances 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 claims description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 2
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 2
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims description 2
- 229960004029 silicic acid Drugs 0.000 claims description 2
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 2
- 241001664510 Saussurea costus Species 0.000 claims 3
- 235000011194 food seasoning agent Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 12
- 239000008280 blood Substances 0.000 abstract description 10
- 210000004369 blood Anatomy 0.000 abstract description 10
- 208000024891 symptom Diseases 0.000 abstract description 9
- 230000002265 prevention Effects 0.000 abstract description 3
- 238000001816 cooling Methods 0.000 abstract description 2
- 230000000740 bleeding effect Effects 0.000 abstract 4
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 239000002324 mouth wash Substances 0.000 abstract 1
- 229940051866 mouthwash Drugs 0.000 abstract 1
- 229940041678 oral spray Drugs 0.000 abstract 1
- 239000000668 oral spray Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 244000272264 Saussurea lappa Species 0.000 description 17
- 238000003756 stirring Methods 0.000 description 14
- 239000000463 material Substances 0.000 description 9
- 239000000843 powder Substances 0.000 description 8
- 210000004195 gingiva Anatomy 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 208000007565 gingivitis Diseases 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 206010018286 Gingival pain Diseases 0.000 description 3
- 206010018291 Gingival swelling Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 description 2
- 208000004078 Snake Bites Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 229960001866 silicon dioxide Drugs 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- OQUFOZNPBIIJTN-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;sodium Chemical compound [Na].OC(=O)CC(O)(C(O)=O)CC(O)=O OQUFOZNPBIIJTN-UHFFFAOYSA-N 0.000 description 1
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 208000003014 Bites and Stings Diseases 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 229920001202 Inulin Polymers 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000208343 Panax Species 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 241000531795 Salmonella enterica subsp. enterica serovar Paratyphi A Species 0.000 description 1
- 241000133134 Saussurea Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 239000012496 blank sample Substances 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 235000015111 chews Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 238000003682 fluorination reaction Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 229940029339 inulin Drugs 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229940068977 polysorbate 20 Drugs 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 239000004323 potassium nitrate Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 1
- 229940048086 sodium pyrophosphate Drugs 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229910001631 strontium chloride Inorganic materials 0.000 description 1
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 description 1
- 238000000194 supercritical-fluid extraction Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940095688 toothpaste product Drugs 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a plant composition and application thereof to preparation of an oral care product. The plant composition takes the mixture of two or three of rhizoma paridis extract, radix notoginseng extract and radix saussureae lappae extract as an active component and is added into oral care products including toothpaste, mouthwash, oral spray and the like; the adding amount is 0.01 percent to 10.0 percent, preferably 1.0 percent to 5.0 percent. The traditional Chinese medicine extracts are added into the oral care product, and rhizoma paridis, radix notoginseng or radix saussureae lappae are used as the component with the effects of clearing away heat and detoxifying, cooling blood and stopping bleeding and are added into the oral care product, so that the oral care product has the effects of alleviating bleeding gums, swollen gums and gum inflammation and has good prevention and treatment effects on common symptoms including the bleeding gums, the swollen gums and the gum inflammation. The oral care product has rapid effect and no toxic side effect, is suitable for utilization when the bleeding gum symptom occurs and is also suitable for prevention in daily life.
Description
Technical field
The present invention relates to oral care product technical field, particularly relate to a kind of vegetable composition and the application in preparing oral care product thereof.
Background technology
The most common oral care product has toothpaste, collutory, mouthspray etc., and its basic function is cleaning tooth, maintains oral health, with
The raising of Living consumption, the oral cavity health consciousness of consumer strengthens day by day, more refines the demand of oral care product, particular for certain
The oral care product of Oral symptoms such as sensitivity of tooth, gingival hemorrhage, gingival swelling and pain etc. is increasingly by consumers.Gingival hemorrhage is that oral cavity is normal
See one of symptom, refer to that gingiva is idiopathic or owing to what outside minimal irritation caused bleeds on a small quantity.The lighter shows as only sucking, brush teeth, chewing
With the blood streak in saliva during harder food, severe one is the most hemorrhage more even hematostaxis when gingiva is by minimal irritation.Relevant research shows: by
Stimulating in bad living habit or vinegar-pepper diet, increasing crowd is perplexed by gingival hemorrhage.Gingival hemorrhage strong influence people's
Daily life, thereby produces the consumption demand for gingival hemorrhage.China's natural resources of Chinese medicinal materials enriches, and the Chinese medicine ingredients with hemostasia effect is a lot, and
The oral care product of interpolation Chinese medicine extract is increasingly by consumers welcomed, therefore, utilizes safely and effectively plant extract to add as activity
Agent, develops a kind of oral care product with alleviation gingival hemorrhage symptom and has certain market value.
Summary of the invention
It is an object of the invention to provide a kind of vegetable composition and the application in preparing oral care product thereof, be that Rhizoma Paridis extract, Radix Notoginseng are carried
Take in thing, Saussurea lappa Clarke extract two or three mixture as active component, join the mouth care such as toothpaste, collutory, mouthspray
In product, there is the effect alleviating gingival hemorrhage, red swelling of gingiva, gingivitis.
It is an object of the invention to be achieved through the following technical solutions:
The vegetable composition of the present invention is that Rhizoma Paridis, Radix Notoginseng, Saussurea lappa Clarke extract the bioactive ingredients that obtains.
The vegetable composition of the present invention, described Rhizoma Paridis, Radix Notoginseng, the extracting method of Saussurea lappa Clarke plant extract are Rhizoma Paridis, Radix Notoginseng or Saussurea lappa Clarke to be crushed
Powdering, with the alcohol reflux 3 hours of 10 times amount, extracts three times continuously, then extracting solution concentrating under reduced pressure is become extractum or be dried to powder
Shape.
The application in preparing oral care product of the vegetable composition of the present invention, vegetable composition recited above becomes as preventing and treating gingival hemorrhage effect
Dividing and be added in oral care product, addition is 0.01%～10.0%.
The application in preparing oral care product of the vegetable composition of the present invention, described oral care product is toothpaste, collutory, mouthspray etc..
The application in preparing oral care product of the vegetable composition of the present invention, the application in toothpaste of the described vegetable composition, by vegetable composition
As preventing and treating gingival hemorrhage functional component join in toothpaste matrix, described vegetable composition percentage by weight in the total mastic of toothpaste be 0.01%～
10.0%, preferably 1.0%～5.0%.
The application in preparing oral care product of the vegetable composition of the present invention, the application in collutory of the described vegetable composition, by plant society
Thing joins in collutory substrate as preventing and treating gingival hemorrhage functional component, and described plant extract percentage by weight in collutory raw material is
0.01%～10.0%, preferably 1.0%～5.0%.
The application in preparing oral care product of the vegetable composition of the present invention, the application in mouthspray of the described vegetable composition, by plant group
Compound joins in mouthspray substrate as preventing and treating gingival hemorrhage functional component, described vegetable composition percentage by weight in mouthspray raw material
It is 0.01%～10.0%, preferably 1.0%～5.0%.
The application in preparing oral care product of the vegetable composition of the present invention, the application in toothpaste of the described vegetable composition, described toothpaste comprises
Each raw material components of following percentage by weight:
Described grinding agent is the mixed of one or more in hydrated silica, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, aluminium hydroxide, microcrystalline Cellulose
Compound；Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol；Described adhesion agent is cellulose
Glue, carrageenan, xanthan gum, guar gum, the mixture of one or more of inorganic gel；Described foaming agent is laurilsulfate sodium or potassium
Salt, cocamido propyl betaine, the mixture of one or more of sodium lauroyl sarcosine；Described sweeting agent is saccharin sodium, sucralose, sweet
Inulin glycosides, the mixture of one or more of aspartame；Other compositions described are preservative, pigment, water, functional additive.
The application in preparing oral care product of the vegetable composition of the present invention, the application in collutory of the described vegetable composition, described collutory
Comprise each raw material components of following percentage by weight:
Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol, xylitol；Described emulsifying
Agent is the mixture of one or more in tween, polyoxyethylene and polyoxypropylene block copolymers, castor oil hydrogenated polyoxyethylene ether；Described sweet taste
Agent is the mixture of one or more of saccharin sodium, sucralose, stevioside, aspartame；Other compositions described be preservative, pigment,
Water, functional additive.
The application in preparing oral care product of the vegetable composition of the present invention, the application in mouthspray of the described vegetable composition, described mouth
Chamber spraying comprises each raw material components of following percentage by weight:
Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol, xylitol；Described emulsifying agent is
The mixture of one or more in tween, polyoxyethylene and polyoxypropylene block copolymers, castor oil hydrogenated polyoxyethylene ether；Described flavoring agent is
The mixture of one or more in Mentholum, Borneolum Syntheticum, menthyl lactate；Described sweeting agent is saccharin sodium, sucralose, stevioside, A Si
The mixture of one or more of Ba Tian；Other compositions described are water, preservative, pigment, functional additive.
Advantages of the present invention and providing the benefit that:
1, Rhizoma Paridis, Radix Notoginseng or Saussurea lappa Clarke are added in oral care product as cooling blood for hemostasis functional component by the present invention first,
It is remarkably reinforced by its alleviation gingival hemorrhage effect of clinical trial certificate.
2, the oral care product of the present invention has the effect alleviating gingival hemorrhage, red swelling of gingiva, gingivitis, and instant effect, has no side effect,
Both it had been suitable for when gingival hemorrhage symptom occurs using, and also had been adapted in daily life prevention and uses.
Detailed description of the invention
The vegetable composition of the present invention and the application in preparing oral care product thereof, i.e. when preparing oral care implement, make plant extract
Join in oral care implement for hemostasis active component.The oral care product of the present invention can use in daily life, reaches slow during routine use
Solve the purpose of gingival hemorrhage, may also function as preventing gingival hemorrhage, alleviating the effect of gingival swelling and pain.
The present invention is to use with the form of Rhizoma Paridis, Radix Notoginseng, Saussurea lappa Clarke extract, Rhizoma Paridis, Radix Notoginseng, the extracting method of Saussurea lappa Clarke be by Rhizoma Paridis, three
Seven or Saussurea lappa Clarke be broken into powdery, with the alcohol reflux 3 hours of 10 times amount, extract continuously three times, then extracting solution concentrating under reduced pressure become leaching
Cream or be dried to powdery.Rhizoma Paridis, Radix Notoginseng, the extracting method of Saussurea lappa Clarke are not limited to said method, and supercritical extraction, ultrasound wave also can be used to extract
The additive method such as take to extract, it is possible to use existing commercially available Rhizoma Paridis, Radix Notoginseng, Saussurea lappa Clarke extract.
Described Rhizoma Paridis, Chinese medicine name.For liliaceous plant Rhizoma Paridis or the dry rhizome of Rhizoma Paridis.Its bitter in the mouth, cold nature；Slightly poisonous.Have
Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, effect of cool liver arresting convulsion, it is usually used in furuncle carbuncle, laryngopharynx swelling and pain, snake bite and insect sting, falls and flutter the pain of injury, convulsion with spasms.
Radix Notoginseng, Chinese medicine name.Main product, in Yunnan Wenshan Prefecture, therefore named mountain of papers Radix Notoginseng, has another name called literary composition state Radix Notoginseng, for panax araliaceae plant Panax notoginseng
(Burk.) dry root of F.H.Chen and rhizome.Autumn excavates before the flowers are in blossom, cleans, and separately main root, a root and rhizome, be dried., Compendium of Material Medica:
Styptic powder blood analgesic therapy, gold sword arrow wound, fall flutter flogging injury, blood goes out more than person, chews rotten painting, or mixes it for end, its blood i.e. stops.The most main hematemesis and epistaxis, under
Blood dysentery, metrorrhagia incessant menorrhea, puerperal stagnant blood not under, blood fortune blood pain, Akamu carbuncle, tiger stings all diseases of snakebite.
Saussurea lappa Clarke (Classification system: sauussurea costus) is the perennial herb of chrysanthemum mesh, Compositae, Genus Saussurea, high 100-200 centimetre.Main
Root is sturdy, cylindrical, has special aroma.Blade triangular shape is avette or Yangtze River Delta shape, and leaf margin is shallow to be split or wavy；Stem leaf oblong.Achene line
Shape.Florescence 7～August, really phase 8～October.It is born in the ground such as Chinese yunnan.Saussurea lappa Clarke water decoction in vitro has slight suppression to Salmonella paratyphi first
Effect, has inhibitory action to some pathomycete, the inhibitory action that trichomonal vaginitis is also had by vitro tests.
In the present invention embodiment all by Rhizoma Paridis, Radix Notoginseng, Saussurea lappa Clarke extract powder as a example by, but be not limited to that extract powder or extractum etc..When with it
When the mode of his form such as extracting solution is applied in oral care product, its addition in formula can root
Suitably convert according to active component content.
Below by way of specific embodiment, the present invention is expressed in further detail, but the present invention is not limited in below example.Following examples
In, involved percentage ratio except as otherwise noted, is all calculated in weight percent.
Embodiment 1-5
Plant extract application in toothpaste:
The toothpaste constitutive material of embodiment 1-5 and weight percent content are as shown in table 1 below.
The raw material of toothpaste composition of table 1 embodiment 1-5
Wherein the processing technology of embodiment 1 comprises the following steps:
1) by little for the solids such as load weighted Rhizoma Paridis extract, Radix Notoginseng extract, Saussurea lappa Clarke extract, saccharin sodium, sucralose, sodium benzoate
Material puts in premixing tank, and stirring sucks in Manufacturing medicine extract machine after making material fully dissolve, and starts agitator and stirs 2～3 minutes；
2) liquid materials such as appropriate sorbitol, glycerol, Polyethylene Glycol are sucked in Manufacturing medicine extract machine, start agitator and stir；
3) cellulose gum, xanthan gum, calcium carbonate are put into together with the silicon dioxide of half amount filler bin, and stir 5～10 minutes,
It is allowed in powder cabin mixing；Sucking in Manufacturing medicine extract machine by material in powder cabin again, homogenizing stirs 20～30 minutes；
4) by balancing silicon dioxide with laurilsulfate sodium, addition Manufacturing medicine extract machine, the most quickly stir
15 minutes；
5) essence measured, cocamido propyl betaine are added in Manufacturing medicine extract machine, unlatching vacuum stirring 10～15 minutes；I.e. obtain cream
Body.
Formula also can add other both effectiveness raw materials, such as anti-sensitive composition such as potassium nitrate, strontium chloride etc., mothproof composition such as sodium monofluorophosphate, fluorination
Sodium etc., whitening composition such as hydrogen peroxide, sodium pyrophosphate, sodium citrate etc., such as pH adjusting agent such as disodium hydrogen phosphate, sodium dihydrogen phosphate, citric acid
Sodium etc..
The preparation method of the tooth paste product of other embodiments 2-4 above-mentioned is with reference to embodiment 1.
Embodiment 6-10
Plant extract application in collutory
The collutory constitutive material of embodiment 6-10 and percentage by weight are as shown in table 2 below.
The collutory raw material composition of table 2 embodiment 6-10
The preparation method of the collutory of above-described embodiment 7 comprises the following steps that:
The solid small powders such as Rhizoma Paridis extracting solution, Radix Notoginseng extracting solution, Saussurea lappa Clarke extracting solution, saccharin sodium, Nipagin complex esters sodium are added to the water, stirring 2～
Within 3 minutes, it is allowed to fully dissolve；It is subsequently adding sorbitol, glycerol etc., stirs and make system mix homogeneously in 3～5 minutes；Poloxamer is molten
Solution, in propylene glycol, adds in liquid phase together with Cremophor RH40, stirs and is allowed to be uniformly dissolved for 20～30 minutes；Add
Essence, stirring is to forming transparent uniform solution；Stand, filter after to squeeze into storage tank etc. to be filled.
The preparation method of the collutory of other embodiments 7-10 above-mentioned is with reference to embodiment 7.
Embodiment 11-15
Plant extract application in mouthspray
The mouthspray constitutive material of embodiment 11-15 and percentage by weight are as shown in table 3 below.
The mouthspray constitutive material of table 3 embodiment 11-15
The preparation method of the mouthspray of above-described embodiment 11 is as follows:
The solid small powders such as Rhizoma Paridis extract, Radix Notoginseng extract, Saussurea lappa Clarke extract, Nipagin complex esters sodium, saccharin sodium, sucralose are added
In water, stir and be allowed to dissolve for 2～3 minutes；Polysorbate-20 is dissolved in propylene glycol, with Cremophor RH40 one
Rise and add in liquid phase, be subsequently adding sorbitol, glycerol, stir and make system uniform in 15～30 minutes；Add ethanol, be eventually adding thin
Lotus brain, essence, stirring is to forming transparent uniform solution；Storage tank etc. is squeezed into be filled after filtration.
The preparation technology of the mouthspray of other embodiments 12-15 above-mentioned is with reference to embodiment 11.
Clinical experiment
Toothpaste containing vegetable composition is carried out clinical experiment, and this toothpaste is carried out together with reference substance with the blank sample without any functional component
Clinical verification, compares hemorrhage index BOP% of gingivitis of two groups of experimenters, when meeting (comparison-experiment)/comparison >=15%,
Product has and improves gingival hemorrhage effect, as shown in table 4 below.
The table 4 toothpaste containing plant extract carries out clinical experiment
| Sample | BOP baseline value | After 4 weeks | After 12 weeks |
| Containing Chinese medicine ingredients toothpaste | 3.74% | 2.65 | 1.17 |
| Without Chinese medicine ingredients toothpaste | 4.35% | 3.36 | 1.99 |
From above-mentioned table 4 data: tested by double blind random, two kinds of toothpaste are used all to have no adverse reaction.Use the toothpaste group of the present invention relatively
The hemorrhage index of BOP% i.e. gingivitis using blank group toothpaste experimenter improves significantly, and the toothpaste of the prompting present invention has significantly improvement
Gingival hemorrhage effect.
The oral care product made according to above-mentioned formula, user every day the most once or uses when having gingival hemorrhage symptom, can alleviate gingiva
The symptoms such as hemorrhage, gingival swelling and pain, aphtha.Use this product can reduce the frequency that gingiva problem occurs during without any symptom.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the dosage or formula made under the present invention enlightens, and is ability
Field technique personnel obviously change, every technical scheme with the present invention with same or like composition, belongs to the protection model of the present invention
Enclose.
Claims (10)
1. a vegetable composition, it is characterised in that: described vegetable composition is that Rhizoma Paridis, Radix Notoginseng, Saussurea lappa Clarke extract the bioactive ingredients that obtains.
2. vegetable composition as claimed in claim 1, it is characterised in that: described Rhizoma Paridis, Radix Notoginseng, the extracting method of Saussurea lappa Clarke plant extract
It is that Rhizoma Paridis, Radix Notoginseng or Saussurea lappa Clarke are broken into powdery, with the alcohol reflux 3 hours of 10 times amount, extracts continuously three times, then will extract
Liquid concentrating under reduced pressure becomes extractum or is dried to powdery.
3. the vegetable composition application in preparing oral care product, it is characterised in that: the vegetable composition described in claim 1 is as anti-
Controlling gingival hemorrhage functional component to be added in oral care product, addition is 0.01%～10.0%.
The vegetable composition the most according to claim 3 application in preparing oral care product, it is characterised in that: described oral care product
For toothpaste, collutory, mouthspray etc..
The vegetable composition the most according to claim 3 application in preparing oral care product, it is characterised in that: described vegetable composition exists
Application in toothpaste, joins in toothpaste matrix using vegetable composition as preventing and treating gingival hemorrhage functional component, and described vegetable composition is total at toothpaste
Percentage by weight in mastic is 0.01%～10.0%, preferably 1.0%～5.0%.
The vegetable composition the most according to claim 3 application in preparing oral care product, it is characterised in that: described vegetable composition
Application in collutory, joins in collutory substrate using vegetable composition as preventing and treating gingival hemorrhage functional component, and described plant extract exists
Percentage by weight in collutory raw material is 0.01%～10.0%, preferably 1.0%～5.0%.
The vegetable composition the most according to claim 3 application in preparing oral care product, it is characterised in that: described vegetable composition exists
Application in mouthspray, joins in mouthspray substrate using vegetable composition as preventing and treating gingival hemorrhage functional component, described vegetable composition
Percentage by weight in mouthspray raw material is 0.01%～10.0%, preferably 1.0%～5.0%.
The vegetable composition the most according to claim 5 application in preparing oral care product, it is characterised in that: described vegetable composition
Application in toothpaste, described toothpaste comprises each raw material components of following percentage by weight:
Described grinding agent is the mixing of one or more in hydrated silica, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, aluminium hydroxide, microcrystalline Cellulose
Thing；Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol；Described adhesion agent is cellulose
Glue, carrageenan, xanthan gum, guar gum, the mixture of one or more of inorganic gel；Described foaming agent be laurilsulfate sodium or
Potassium salt, cocamido propyl betaine, the mixture of one or more of sodium lauroyl sarcosine；Described sweeting agent be saccharin sodium, sucralose,
Stevioside, the mixture of one or more of aspartame；Other compositions described are preservative, pigment, water, functional additive.
The vegetable composition the most according to claim 6 application in preparing oral care product, it is characterised in that: described vegetable composition exists
Application in collutory, described collutory comprises each raw material components of following percentage by weight:
Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol, xylitol；Described emulsifying agent be tween,
The mixture of one or more in polyoxyethylene and polyoxypropylene block copolymers, castor oil hydrogenated polyoxyethylene ether；Described sweeting agent is saccharin
Sodium, sucralose, stevioside, the mixture of one or more of aspartame；Other compositions described are preservative, pigment, water, effect
Additive.
The vegetable composition the most according to claim 7 application in preparing oral care product, it is characterised in that: described plant society
Thing application in mouthspray, described mouthspray comprises each raw material components of following percentage by weight:
Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol, xylitol；Described emulsifying agent
For the mixture of one or more in tween, polyoxyethylene and polyoxypropylene block copolymers, castor oil hydrogenated polyoxyethylene ether；Described seasoning
Agent is the mixture of one or more in Mentholum, Borneolum Syntheticum, menthyl lactate；Described sweeting agent be saccharin sodium, sucralose, stevioside,
The mixture of one or more of aspartame；Other compositions described are water, preservative, pigment, functional additive.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610537799.7A CN105963216A (en) | 2016-07-08 | 2016-07-08 | Plant composition and application thereof to preparation of oral care product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610537799.7A CN105963216A (en) | 2016-07-08 | 2016-07-08 | Plant composition and application thereof to preparation of oral care product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105963216A true CN105963216A (en) | 2016-09-28 |
Family
ID=56952154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610537799.7A Pending CN105963216A (en) | 2016-07-08 | 2016-07-08 | Plant composition and application thereof to preparation of oral care product |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105963216A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157424A (en) * | 2018-10-12 | 2019-01-08 | 赵孔发 | A kind of preparation method and applications of Japan pepper essential oil microcapsules |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1823719A (en) * | 2005-02-25 | 2006-08-30 | 韩志成 | Oral cavity fragrant medicine additive for tooth paste |
| CN101023914A (en) * | 2007-03-23 | 2007-08-29 | 昆明牙膏有限责任公司 | Toothpaste containing notoginseng extract and preparing method |
| CN102144958A (en) * | 2011-04-14 | 2011-08-10 | 云南文山七丹药业股份有限公司 | Notoginsenoside-containing medicinal toothpaste and preparation method thereof |
| CN102670442A (en) * | 2012-05-14 | 2012-09-19 | 云南云科药业有限公司 | Panax notoginseng active ingredient-containing medicinal toothpaste and preparation method and application thereof |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104840388A (en) * | 2015-04-29 | 2015-08-19 | 广州立白企业集团有限公司 | Application of plant extracts to oral care products |
-
2016
- 2016-07-08 CN CN201610537799.7A patent/CN105963216A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1823719A (en) * | 2005-02-25 | 2006-08-30 | 韩志成 | Oral cavity fragrant medicine additive for tooth paste |
| CN101023914A (en) * | 2007-03-23 | 2007-08-29 | 昆明牙膏有限责任公司 | Toothpaste containing notoginseng extract and preparing method |
| CN102144958A (en) * | 2011-04-14 | 2011-08-10 | 云南文山七丹药业股份有限公司 | Notoginsenoside-containing medicinal toothpaste and preparation method thereof |
| CN102670442A (en) * | 2012-05-14 | 2012-09-19 | 云南云科药业有限公司 | Panax notoginseng active ingredient-containing medicinal toothpaste and preparation method and application thereof |
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN104840388A (en) * | 2015-04-29 | 2015-08-19 | 广州立白企业集团有限公司 | Application of plant extracts to oral care products |
Non-Patent Citations (1)
| Title |
|---|
| 黄璐琦等主编: "《国珍稀濒危药用植物资源调查》", 31 January 2012 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157424A (en) * | 2018-10-12 | 2019-01-08 | 赵孔发 | A kind of preparation method and applications of Japan pepper essential oil microcapsules |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104207982B (en) | Prevent Chinese medicine composition and the oral care product containing it that oral cavity is got angry | |
| CN103520052B (en) | Bletilla striata extract is preparing the application in oral care product | |
| CN104840388A (en) | Application of plant extracts to oral care products | |
| KR101481371B1 (en) | Toothpaste composition containing Curcuma longa L and production method thereof | |
| CN103520076B (en) | Compound Chinese medicine extract is preparing the application in oral cavity nursing health products | |
| CN105055223A (en) | Traditional Chinese medicine toothpaste capable of stopping bleeding and desensitizing | |
| KR20120133799A (en) | Functional soap and manufacturing method of it | |
| CN103520049A (en) | Application of compound traditional Chinese medicine extracts in preparation of health care products for oral care | |
| CN109276475A (en) | A kind of traditional Chinese medicine toothpaste containing white and polysaccharide and preparation method thereof | |
| CN112569152A (en) | Oil-control anti-inflammatory plant combined extract and preparation method and application thereof | |
| CN102961295A (en) | Application of caulis sinomenii extract to preparation of oral care products | |
| CN101869542B (en) | Toner comprising pawpaw extract and lotus leaf extract and preparation method thereof | |
| CN103462877B (en) | A kind of dentifrice composition containing active composition inclusion | |
| CN104983752B (en) | A kind of Chinese medicine composition that treating mouth disease, oral-cavity article and preparation method | |
| CN105496830A (en) | Preparation method of alpinia japonica extract and application thereof in personal care products | |
| CN105963216A (en) | Plant composition and application thereof to preparation of oral care product | |
| CN105287328A (en) | Manuka honey toothpaste for pregnant women and preparation method of toothpaste | |
| CN105147583A (en) | Special camellia-saponin-contained toothpaste for child and preparation method thereof | |
| CN105031083A (en) | Application of traditional Chinese medicine composition in oral care products | |
| CN105012174A (en) | Chinese herbal toothpaste containing vitamin C and preparation method of Chinese herbal toothpaste | |
| CN104224981A (en) | Traditional Chinese medicine composition for improving gum and periodontal health and toothpaste containing same | |
| KR20220110700A (en) | Oral composition | |
| CN103520054B (en) | Ramulus Uncariae Cum Uncis extract application in preparing oral care product | |
| CN106176477A (en) | A kind of protective skin cream | |
| CN106620349A (en) | Medicine composition for nourishing yin of lung and kidney, cooling blood and realizing hemostasis and preparation method of medicine composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160928 |
|
| WD01 | Invention patent application deemed withdrawn after publication |