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CN105943463B - A kind of mild baby child's hair washing shower bubble - Google Patents

A kind of mild baby child's hair washing shower bubble Download PDF

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Publication number
CN105943463B
CN105943463B CN201610466729.7A CN201610466729A CN105943463B CN 105943463 B CN105943463 B CN 105943463B CN 201610466729 A CN201610466729 A CN 201610466729A CN 105943463 B CN105943463 B CN 105943463B
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baby child
alpha
mild
baby
skin
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CN105943463A (en
Inventor
周丽娟
王英
钟勤雄
林占亮
傅珊珊
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Golden Day Pharmaceutical (china) Co Ltd
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Golden Day Pharmaceutical (china) Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/604Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of mild baby child's hair washing shower bubbles, it is directed to the characteristics of baby Tong Maofa and skin quality, select cocounut oil acyl disodium glutamate, Cocoamidopropyl betaine and sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium compounding are used as surfactant system, select camellia seed oil, alpha-glucans oligosaccharides/inulin compound is as conditioning ingredients, Flos Chrysanthemi Indici extract and lauroyl arginine ethyl ester HCl compounding are used as protective system, each raw material cooperates with each other in the present invention, cleaning effect is good, it is mild non-stimulated, strengthen skin barrier simultaneously, give the virgin intimate care of baby.

Description

A kind of mild baby child's hair washing shower bubble
Technical field
The present invention relates to a kind of mild baby child's hair washing shower bubbles, belong to baby child's technical field of daily necessities.
Background technique
Compared to adult skin, baby child's skin is thin, iuntercellular attachment is weak, water content is high, fat secretion is few, to external irritant The sensibility of object is high.On hair, baby child is few compared with terminal hair, by external irritant (such as hair dryer, dyeing and perm is straightened) influence because Element is few.Therefore the most important of baby child's hair washing bath product is exactly mild non-stimulated.
1, the irritation of hair washing bath product is mainly derived from surfactant and preservative
Surfactant: the bath product of baby child's hair washing currently on the market is mostly sulfate surfactant system, irritation Greatly, there is absorption to skin, the harmful substances such as dioxanes can be introduced.Although some products use mild amino acid surfactant System, because its is at high cost, promote at present it is less, and amino acid surfactant system difficulty thickening also become industry a disaster Point, by the way that thickener such as carbomer SF-1, PEG-120 methyl glucose dioleate, PEG-18 glycerol oleic acid/coconut oil is added Ester etc. or adjustment behave of the PH from thickening of enlarged surface activating agent dosage can all increase baby child's skin burden.
Preservative: currently on the market generally using parabens, formaldehyde donor class or Kathon CG etc., it was reported that these anti-corrosions There is certain irritation to human body in agent.Suitable surfactant system and protective system is selected to guarantee that product safety has Effect, while giving the virgin mild care of baby is current technical problem urgently to be solved.
2, the care of skin Tiny ecosystem
Although baby child has one's hair wash, bath product can generally add grease, moisturizing, submissive ingredient improve, and have ignored baby child Another important skin protection path, that is, skin Tiny ecosystem.The microorganism of the skin surface of baby child, which colonizes process and originates in, gave a birth Journey, and gradually consolidated along with the maturation of neonatal immune system in skin surface after birth.The micro- life settled down on skin The object ecological niche different with skin surface collectively forms the Tiny ecosystem of skin complexity.The flora of skin surface be divided into resident flora and Stay temporarily flora, it is most of be all to body it is beneficial, such as clear up the rubbish (cell of apoptosis) of skin surface;Decompose extra rouge Matter;By the immune system of Reverse transcriptase while stimulation of host, enhance the immunity and resistance of host, to resist exotic disease Opportunistic pathogen invasion.But when the relationship of balancing each other is broken skin function will disorder, frequently occurred so as to cause such as baby child Allergic skin diseases.Therefore the health of concern baby child's skin Tiny ecosystem is of great significance.
In order to solve the deficiencies in the prior art, market needs one kind and can maximize to play property of raw material and take jointly It builds and gives the virgin mild non-stimulated watch box of washing of baby and test and environmental-friendly wash shield product.
Summary of the invention
It is an object of the invention to overcome above-mentioned the deficiencies in the prior art, a kind of mild baby child's hair washing shower bubble is provided Bubble.
To achieve the above object, the invention adopts the following technical scheme:
A kind of mild baby child's hair washing shower bubble, is made of the following components: cocounut oil acyl glutamic acid two by weight percentage Sodium 5~20%, Cocoamidopropyl betaine 5~20%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 3~ 10%, camellia seed oil 0.1~0.4%, alpha-glucans oligosaccharides/inulin compound 0.5~2.5%, Flos Chrysanthemi Indici extract 1~ 10%, lauroyl arginine ethyl ester HCl 0.5%~0.8%, surplus is deionized water.
Preferably, it is made of the following components by weight percentage: cocounut oil acyl disodium glutamate 5%, cocamidopropyl propyl amide sweet tea Dish alkali 20%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 3%, camellia seed oil 0.1%, alpha-glucans oligosaccharides/chrysanthemum Powder compound 0.5%, Flos Chrysanthemi Indici extract 10%, lauroyl arginine ethyl ester HCl 0.5%, surplus is deionized water.
Preferably, it is made of the following components by weight percentage: cocounut oil acyl disodium glutamate 9%, cocamidopropyl propyl amide sweet tea Dish alkali 15%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 10%, camellia seed oil 0.15%, alpha-glucans oligosaccharides/ Inulin compound 0.7%, Flos Chrysanthemi Indici extract 9%, lauroyl arginine ethyl ester HCl 0.8%, surplus is deionized water.
After adopting the above technical scheme, compared with the background technology, the present invention, having the advantages that
1, with natural origin ingredient cocounut oil acyl disodium glutamate, Cocoamidopropyl betaine and sulfonic acid hydroxypropyl acrylate lauryl Glucoside cross-linked polymer sodium compounding is used as surfactant system.Rise soak, cleaning effect is good, Yi Chongxi, at the same solve with Lower Railway Project: (1) mildly, sliding with rear hair and skin comfort, silk.It avoids using traditional Sulfates surfactant Irritation, bringing into harmful substances such as the absorption of skin and dioxanes.(2) system is in bubble shape after pump head squeezes out It can be used, effectively solve the thickening of amino acid surfactant system difficulty, used by using thickener or enlarged surface activating agent Amount adjustment PH is from the problem of thickening, increasing the burden of skin.Convenience and enjoyment when increasing baby bath simultaneously.(3) full Demand of the sufficient consumer to natural origin ingredient.(4) more environmentally friendly.Reinforce the research of surfactant biological degradability, effectively Control the deterioration of the ecological environment, it has also become one of current important topic.Three kinds of surfactants of compounding derive from biological object Matter, renewable, biological degradability is good, mitigates biodegradable pressure from source.
2, alpha-glucans oligosaccharides/inulin compound 0.5~2.5% is added, to safeguard the skin Tiny ecosystem health of baby child, and As the important channel for strengthening baby child's skin barrier.Our experiments show that alpha-glucans oligosaccharides/inulin compound can be used as it is beneficial Bacterium nutriment makes it mushroom out breeding, maintains the status of dominant bacteria, and pathogen is made not have enough nutrient growth, thus Inhibit pathogen breeding, strengthens baby child's skin barrier.
3, use compounding natural origin ingredient as protective system.Cosmetics guarantee it safely and effectively in shelf life, It will addition preservative.Generally using parabens, formaldehyde donor class or Kathon CG etc., it was reported that these preservatives are equal to human body There are certain irritations.Baby child bears a pretty, delicate skin, and the natural origin ingredient with fungistatic effect should be selected to compound to form anti-corrosion System.Our experiments show that regarding Flos Chrysanthemi Indici extract and lauroyl arginine ethyl ester HCl compounding as protective system, can obtain Mild watch box of washing is tested and effective anti-corrosion.Flos Chrysanthemi Indici extract has killing or inhibitory activity to various pathogens, virus, simultaneously It is preferred that addition has good fungistatic effect to gram-positive bacteria, Gram-negative bacteria, pathogen, yeast and mould, and most The universal lower lauroyl arginine ethyl ester HCl of low inhibition concentration.Flos Chrysanthemi Indici extract is containing flavonoids, half terpenes, more simultaneously The a variety of active ingredients such as sugar, alantol, amino acid and microelement have anti-inflammatory, Repercusion analgesia activity.
4, it is especially added with natural plants camellia seed oil.Camellia seed oil is the advantage oil product in China, the unsaturated lipid contained Fat acid content is up to 90%, and is rich in the microelements such as vitamin E and calcium, iron, zinc, effectively skin care and hair.Civil Camellia seed oil serves not only as the moisturizing of baby child's skin, is also used for skin allergy and the antibacterial treatment of anti-inflammatory.Therefore, camellia seed oil is made Multiple action can be played in prescription for excellent plant origin.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Embodiment 1
Preparation baby child's hair washing shower bubble: cocounut oil acyl disodium glutamate 5%, coconut oleoyl amine is matched by following weight percent Propyl betaine 20%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 3%, camellia seed oil 0.1%, alpha-glucans are few Sugar/inulin compound 0.5%, Flos Chrysanthemi Indici extract 10%, lauroyl arginine ethyl ester HCl 0.5%, surplus are deionized water.
Wherein the weight ratio of alpha-glucans oligosaccharides and inulin is (0.3-2) in alpha-glucans oligosaccharides/inulin compound: 1, this The preferred 1:1 of embodiment.
Embodiment 2
Preparation baby child's hair washing shower bubble: cocounut oil acyl disodium glutamate 9%, coconut oleoyl amine is matched by following weight percent Propyl betaine 15%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 10%, camellia seed oil 0.15%, alpha-glucans Oligosaccharides/inulin compound 0.7%, Flos Chrysanthemi Indici extract 9%, lauroyl arginine ethyl ester HCl 0.8%, surplus are deionization Water.
Embodiment 1-2's the preparation method comprises the following steps: by surface active agent composition, assigning rouge component and water phase components and being warming up to 80 ± 1 DEG C, heat preservation cools down after 15 minutes;Conditioning component is added when cooling to lower than 45 DEG C and main antibacterial component stirs evenly, physics and chemistry refers to Mark discharges after the assay was approved.Physical and chemical index of the invention are as follows: appearance is transparent flow liquid, and pH value 6.5-7.2 resists cold and stablizes Property (- 20 DEG C × for 24 hours) investigate qualification.
The hair washing shower bubble of baby child prepared by embodiment 1-2 is detected:
1. carrying out surfactant to embodiment 1-2 baby child obtained hair washing shower bubble using the molten method of testing of corn alcohol Irritating detection.
Its water solubility adds when zeins (zein) and surfactant almost not soluble in water interacts Greatly, according to the situation of change of nitrogen content in aqueous solution, zein and the solubility after Action of Surfactant, stimulation can be determined Property stronger surfactant it is zein more more soluble than weak irritating surfactant, it is possible thereby to know surfactant pierce Swash the power of property.When Zein value is low irritant in the surfactant of N2g/L~4g/L solution, less than the surface of 2g/L solution Activating agent is nonirritant.
Test result is as follows table:
Embodiment 1 2
Zein value (g/L) 0.221 0.202
As can be seen that the zein value of embodiment 1-2 is respectively less than 2g/L, it is nonirritant.
2, embodiment 1-2 is carried out once using European Pharmacopoeia (Ph.Eur.general text 5.1.3) plus bacterium is tested Investigate its inhibitor effectiveness.
Test result is as follows table:
As can be seen that the bacterium of embodiment 1-2 is reduced more than 2 orders of magnitude on day 2, it is reduced more than 3 quantity within the 7th day Grade, the 28th day without clearly visible growth;Mould was reduced more than 2 orders of magnitude at the 14th day, and the 28th day without clearly visible growth.By Embodiment 1-2 is tested by preservation challenge known to this, has anti-corrosion effect to guarantee product quality.
3, the test of foam satisfaction, Yi Chongxi degree and the moist performance to skin.
Due to baby child be unable to precise expression use when sensory experience and use after effect, choose 2 groups of ages between 18- The young woman of skin delicacy, every group of 6 people respectively test embodiment 1-2 between 22 years old.
Test result is as follows table:
As can be seen that 2 groups of personnel use the foam satisfaction squeezed out when embodiment 1-2 to pump, no eyes and skin irritatin, and It is easy to rinse well, skin moisturizing is not dry taut after trying out.
4, alpha-glucans oligosaccharides/inulin compound strengthens the test of skin barrier.
It is being added to 0.5% alpha-glucans oligosaccharides, 0.5% inulin, 0.5% alpha-glucans oligosaccharides/inulin compound respectively Culture medium in, while being inoculated with kirschner Kocuria kristinae ad (beneficial bacterium) and staphylococcus aureus (pathogen), cultivate 24 hours.
Test result is as follows table:
It can be seen that in the culture medium at the same time containing beneficial bacterium and pathogen, alpha-glucans oligosaccharides/inulin compound ratio It rises and alpha-glucans oligosaccharides, inulin is applied alone, it is more excellent in the effect that the growth for selectively promoting beneficial bacterium reduces pathogen indirectly, it reaches To the effect for strengthening skin barrier.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by anyone skilled in the art, It should be covered by the protection scope of the present invention.Therefore, protection scope of the present invention should be with scope of protection of the claims Subject to.

Claims (3)

  1. The shower bubble 1. a kind of mild baby child has one's hair wash, which is characterized in that be made of the following components by weight percentage: cocounut oil acyl Disodium glutamate 5~20%, Cocoamidopropyl betaine 5~20%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer Sodium 3~10%, camellia seed oil 0.1~0.4%, alpha-glucans oligosaccharides/inulin compound 0.5~2.5%, Flos Chrysanthemi Indici extract 1 ~10%, lauroyl arginine ethyl ester HCl 0.5%~0.8%, surplus is deionized water.
  2. The shower bubble 2. the mild baby child of one kind according to claim 1 has one's hair wash, which is characterized in that by weight percentage by Following component composition: cocounut oil acyl disodium glutamate 5%, Cocoamidopropyl betaine 20%, sulfonic acid hydroxypropyl acrylate lauryl glucose Glycosides cross-linked polymer sodium 3%, camellia seed oil 0.1%, alpha-glucans oligosaccharides/inulin compound 0.5%, Flos Chrysanthemi Indici extract 10%, lauroyl arginine ethyl ester HCl 0.5%, surplus is deionized water.
  3. The shower bubble 3. the mild baby child of one kind according to claim 1 has one's hair wash, which is characterized in that by weight percentage by Following component composition: cocounut oil acyl disodium glutamate 9%, Cocoamidopropyl betaine 15%, sulfonic acid hydroxypropyl acrylate lauryl glucose Glycosides cross-linked polymer sodium 10%, camellia seed oil 0.15%, alpha-glucans oligosaccharides/inulin compound 0.7%, Flos Chrysanthemi Indici extract 9%, lauroyl arginine ethyl ester HCl 0.8%, surplus is deionized water.
CN201610466729.7A 2016-06-23 2016-06-23 A kind of mild baby child's hair washing shower bubble Active CN105943463B (en)

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CN106473958A (en) * 2016-11-04 2017-03-08 深圳市婴缘健康有限公司 A kind of two-in-one hair washing bath oil of infant
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CN109512742A (en) * 2018-12-26 2019-03-26 株洲千金药业股份有限公司 A kind of man's essential oil shower condensation and preparation method thereof
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CN111973522A (en) * 2019-05-22 2020-11-24 思蓝(北京)科技有限公司 Bubble shampoo and shower gel for children
CN110215425A (en) * 2019-06-20 2019-09-10 广州艾蓓生物科技有限公司 A kind of hair washing shower bubble
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CN110885717B (en) * 2019-12-16 2022-04-08 株洲千金药业股份有限公司 Natural antibacterial detergent for lady clothes
CN111135125A (en) * 2020-01-10 2020-05-12 广州贝玛生物科技有限公司 Composition capable of improving stretch marks, postpartum repair moisturizer containing composition and preparation method of postpartum repair moisturizer
CN112245338A (en) * 2020-11-25 2021-01-22 广州环亚化妆品科技有限公司 Self-heating bath bubble and preparation method thereof
CN114259416A (en) * 2021-12-27 2022-04-01 卡莱丽化妆品有限公司 Surfactant composition, and preparation method and application thereof

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CN105050575A (en) * 2013-03-11 2015-11-11 拜尔斯道夫股份有限公司 Combination of alkylamidothiazoles and preservatives
CN105283191A (en) * 2012-09-25 2016-01-27 阿曲龙Cyl有限公司 Probiotic and prebiotic compositions

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Publication number Priority date Publication date Assignee Title
CN1536967A (en) * 2001-07-30 2004-10-13 �Ʒ� Nutritional composition preventing bacterial overgrowth
CN1882351A (en) * 2003-11-21 2006-12-20 希尔氏宠物营养品公司 Composition and method
WO2009031041A3 (en) * 2007-09-04 2010-09-10 Danisco A/S Antimicrobial composition
WO2012055855A1 (en) * 2010-10-29 2012-05-03 Laboratorios Miret, S.A. Concentrated preparations of lae and their use
CN105283191A (en) * 2012-09-25 2016-01-27 阿曲龙Cyl有限公司 Probiotic and prebiotic compositions
CN105050575A (en) * 2013-03-11 2015-11-11 拜尔斯道夫股份有限公司 Combination of alkylamidothiazoles and preservatives

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