CN107998028A - A kind of shower cream and preparation method thereof - Google Patents
A kind of shower cream and preparation method thereof Download PDFInfo
- Publication number
- CN107998028A CN107998028A CN201711420370.0A CN201711420370A CN107998028A CN 107998028 A CN107998028 A CN 107998028A CN 201711420370 A CN201711420370 A CN 201711420370A CN 107998028 A CN107998028 A CN 107998028A
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- Prior art keywords
- agent
- shower cream
- mixture
- weight
- extract
- Prior art date
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Abstract
The present invention is suitable for cosmetic technical field, there is provided a kind of shower cream and preparation method thereof, the shower cream, by weight, including following component：Amphoteric surfactant：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Natural antirot substance：0.1%~1.7%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.Present invention use is pure natural, there is anti-inflammatory, antibacterial, antiviral enzyme preparation or the mixture of enzyme preparation and natural to build natural protective system, it is not only able to play effective anti-corrosion effect, it is and gently non-stimulated to skin, it is safe, the moisture of skin can be kept at the same time, it is not dry and astringent not tight using rear skin.
Description
Technical field
The invention belongs to cosmetic technical field, more particularly to a kind of shower cream and preparation method thereof.
Background technology
Existing commercially available most of shower cream products can all add the different thiophene miaow quinoline ketone of such as methyl, phenmethylol, Phenoxyethanol, benzene
The anti-corrosion compositions such as sodium formate, nipagin esters are to improve the antiseptic property of product, still, found according to current research, it is above-mentioned into
Dividing has skin stronger stimulation, easily causes skin allergy and contact dermatitis.Also, due to infant skin only
Have the thickness of adult application on human skin 1/10th, the collagenous fibres in corium are few, lack flexibility, easily because friction cause skin by
Damage.The immune system of baby itself is not perfect enough, and resistance is weaker, is easier to skin allergy occur.In addition, the skin of infant
Easily absorb foreign object, for the allergin or interfering material in the daily chemical products of same amount, the uptake of infant than
Adult is more, therefore reaction of the infant to allergin or interfering material is stronger.
It can be seen from the above that larger (the especially baby children of irritation of above-mentioned anti-corrosion composition in existing shower cream to skin
Youngster), easily cause skin allergy, inflammation, security is not high.
The content of the invention
The embodiment of the present invention provides a kind of shower cream, it is intended to solves the anti-corrosion composition in existing shower cream to skin irritatin
The problem of property is larger, easily causes skin allergy, inflammation, and security is not high.
The embodiment of the present invention is achieved in that a kind of shower cream, by weight, including following component：Amphoteric surface lives
Property agent：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Natural anticorrosion
Material：0.1%~1.7%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；
Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.
Preferably, the shower cream, by weight, including following component：Amphoteric surfactant：10%~18%；It is non-
Ionic surface active agent：10%~15%；Skin conditioning agent：0.5%~2.5%；Enzyme preparation：0.1%~0.5%；Chelating agent：
0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the enzyme preparation for lysozyme and
Protease, lipase, amylase, superoxide dismutase, Co-Q10 either one kind in collagen hydrolysate enzyme or at least
Two kinds of mixture.
Preferably, the shower cream, by weight, including following component：Amphoteric surfactant：10%~18%；It is non-
Ionic surface active agent：10%~15%；Skin conditioning agent：0.5%~2.5%；Enzyme preparation：0.1%~0.5%；It is anti-oxidant
Agent：0.5%~1.2%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Its
In, the enzyme preparation is lysozyme, protease, lipase, amylase, superoxide dismutase, Co-Q10 or collagen
A kind of in hydrolase or at least two mixture；The antioxidant is parahydroxyacet-ophenone, or para hydroxybenzene second
The mixture of the one of which of ketone and ascorbic acid or Vitamin C dipalmitate.
Preferably, the shower cream, by weight, including following component：Amphoteric surfactant：15%；Nonionic table
Face activating agent：12%；Skin conditioning agent：2.5%；Enzyme preparation：0.5%；Antioxidant：1.2%；Chelating agent：0.12%；PH tune
Save agent：0.1%；Surplus is deionized water.
Preferably, the shower cream, by weight, including following component：Amphoteric surfactant：10%~18%；It is non-
Ionic surface active agent：10%~15%；Skin conditioning agent：0.5%~2.5%；Natural antirot substance：0.1%~1.7%；
Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Emulsifying agent：2.5%~5%；Moisturizer：2.4~5%；
Essence：0.1%~0.2%；Surplus is deionized water.
Preferably, the shower cream, by weight, including following component：Amphoteric surfactant：15%；Nonionic table
Face activating agent：12%；Skin conditioning agent：2.5%；Enzyme preparation：0.5%；Antioxidant：1.2%；Chelating agent：0.12%；PH tune
Save agent：0.1%；Emulsifying agent：4%；Moisturizer：3%；Essence：0.2%；Surplus is deionized water.
Preferably, the amphoteric surfactant is stearamide propyl glycine betaine, lauroyl oat amino acid sodium, cocounut oil
Acyl Sodium Glycinate, Sodium Lauroamphoacetate, lauryl betaine, Cocoamidopropyl betaine or cocounut oil acyl both sexes base
A kind of in diethyl acid disodium or at least two mixture；
The nonionic surfactant is laureth sulfosuccinate disodium, coconut oil list isopropanol amide,
One or two kinds of mixture in coconut monoethanol amide, lauryl glucoside or Plantacare 818；
The emulsifying agent is oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters or oleyl alcohol mustard
One or two kinds of mixture in acid esters；
The moisturizer is glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, Sensiva SC50 or poly-
One or two kinds of mixture in ethylene glycol；
The skin conditioning agent is jojoba seed oil, bisabolol, Flos Chrysanthemi Indici extract, golden yellow camomile extract, grass
At least three kinds of mixture in sweet-scented osmanthus extract, licorice or camellia seed extract；
The chelating agent is sodium glucoheptonate；
The pH adjusting agent is one or two kinds of mixture in citric acid, boric acid, malic acid or sorbic acid.
It is furthermore preferred that the amphoteric surfactant is Cocoamidopropyl betaine and cocounut oil acyl both sexes base oxalic acid two
The mixture of sodium；
The nonionic surfactant is lauryl glucoside and the mixture of Plantacare 818；
The emulsifying agent is PEG-150 distearyl fat acid esters；
The moisturizer is glycerine and the mixture of 1,2- hexylene glycols；
The skin conditioning agent is jojoba seed oil, bisabolol, Flos Chrysanthemi Indici extract, golden yellow camomile extract, grass
The mixture of sweet-scented osmanthus extract, licorice and camellia seed extract；
The pH adjusting agent is citric acid.
Preferably, the amphoteric surfactant includes following material and percentage by weight：Cocoamidopropyl betaine
10% and cocounut oil acyl both sexes base diethyl acid disodium 5%；
The nonionic surfactant includes following material and percentage by weight：Lauryl glucoside 6% and decyl Portugal
Glucosides 6%；
The skin conditioning agent includes following material and percentage by weight：Jojoba seed oil 2%, bisabolol 0.25%,
Flos Chrysanthemi Indici extract 0.01%, golden yellow camomile extract 0.05%, melilotus extract 0.06%, licorice 0.05%
And camellia seed extract 0.08%；
The enzyme preparation includes following material and percentage by weight：Lysozyme 0.5%；
The antioxidant includes following material and percentage by weight：Parahydroxyacet-ophenone 0.2%；
The chelating agent includes following material and percentage by weight：Sodium glucoheptonate 0.12%；
The pH adjusting agent includes following material and percentage by weight：Citric acid 0.1%；
The emulsifying agent includes following material and percentage by weight：PEG-150 distearyl fat acid esters 4%；
The moisturizer includes following material and percentage by weight：Glycerine 2% and 1,2- hexylene glycols 1%；
Essence：0.2%；Surplus is deionized water.
The embodiment of the present invention additionally provides a kind of preparation method of shower cream, includes the following steps：
Step 1：Formula according to above-mentioned shower cream weighs each component, spare；
Step 2：The part deionized water is added into ingredients pot；
Step 3：The amphoteric surfactant, nonionic surfactant are added in the ingredients pot, stirred to complete
Fully dissolved；
Step 4：The skin conditioning agent, chelating agent are put into the ingredients pot, are heated to 50 DEG C~60 DEG C, stirring
To being completely dissolved；
Step 5：The deionized water of surplus is added in the ingredients pot；
Step 6：It is to be cooled when being cooled to 20 DEG C~40 DEG C, the natural antirot substance is added in the ingredients pot, is stirred
Mix to being completely dissolved；
Step 7：The pH adjusting agent is added in the ingredients pot, stirs evenly and adjusts pH to 5.5, is obtained described
Shower cream.
In above-mentioned shower cream the effect of each raw material and component is described as follows：
Stearamide propyl glycine betaine：With excellent decontamination, scattered, emulsification, foaming, foam stabilizing, antistatic, thickening energy
Power.Property is gentle, can reduce the irritation of other surfaces activating agent, resistance to hard water, and compatibility is good.
Lauroyl oat amino acid sodium：It is good with the compatibility of skin, have it is excellent emulsify, disperse, decontamination, antistatic energy
Power.To hair and skin as mild as a dove, there is stronger skin water lock ability, there is provided lasting moisture retention, has remarkable hair
Steep performance and foam stability energy.Under the bad condition such as hard water and sebum greasy dirt, performance is outstanding.Easily thicken, not viscosity reduction.Low colourity,
Low smell, available for no perfumed products.
Sodium cocoyl glycinate：It is widely used in the personal-care supplies such as shampoo, body lotion, facial cleanser field.With skin, hair
Hair has outstanding compatibility, is applicable to sensitive skin type.
Sodium Lauroamphoacetate：Gentle amphoteric surfactant, overall body can be reduced with anion table work compounding
The irritation of system, has excellent foaminess in the range of extensive pH, has a wide range of application, and has fabulous compatibility.With
Human skin structure height is consistent, and security is good, easily biological-degradable.
Lauryl betaine：It is changed to：Lauryl betaine：There are excellent dissolubility and compatibility, there is excellent foaming
Property and significant thickening property, there are low irritant and bactericidal properties, compatible use can significantly improve the softness of washing class product, conditioning
And low-temperature stability, there are thickening properties to soap base.
Cocoamidopropyl betaine：It is a kind of gentle amphoteric surfactant, there is good cleaning, blistering, tune
Reason acts on, good with anion, cation and nonionic surfactant intermiscibility.Irritation is small, performance is gentle, foam it is fine and smooth and
Stablize, thickening properties are excellent, suitable for preparing shampoo, shower cream, facial cleanser etc., can strengthen the flexibility to hair, skin.
Cocounut oil acyl both sexes base diethyl acid disodium：With good surface-active, soil release performance, solubilising, foaming characteristic, spumescence
Matter is stablized.Acid and alkali-resistance, resistance to hard water, compatibility is good, nontoxic non-stimulated, easily biological-degradable.It is antistatic with good rust inhibition
Property.
Laureth sulfosuccinate disodium：Possess pair of nonionic surfactant and anion surfactant
Weight surface chemistry.With performances such as excellent washing, emulsification, scattered, wetting, solubilisings, foaming abundancy, irritation is small, easily
Rinsing, detergency is excellent, and pH use scopes are broad.
Coconut oil list isopropanol amide：With performances such as superpower scattered, purification, emulsification, softnesses, system bubble can effectively improve
Foam, there is good tax fat effect, has preferable foam stabilizing to act on to anion surfactant.
Coconut monoethanol amide：For nonionic surfactant, can match somebody with somebody with anion, cation and amphoteric surfactant
Close and use, and produce synergy.Effective thickened product system, has preferable foam stabilizing effect.It is also used as having one's hair wash at the same time
Shampoo, the viscosity modifier of bath foam.
Lauryl glucoside：With excellent decontamination, foaming, foam stabilizing, emulsification, scattered, solubilising, wetting, penetrating power.It is resistance to
It is sour, alkaline-resisting, it is insensitive to electrolyte, it is good that the irritation of other surfaces activating agent, no cloud point, and skin-friendliness can be reduced.
Plantacare 818：It is one kind in new non-ionic surfactants APG, has both conventional nonionic and anion table
The characteristic of activating agent, it is soluble easily in water, be relatively soluble in common organic solvent, surface tension is low, foaming abundancy, exquisiteness and stablize, it is resistance to
Highly basic strong acid, wetting power be strong, can be with various surfactant compounds, and synergy is obvious, and with harmless, nontoxic, stingless
The special performances such as sharp, biodegradable rapid, complete and sterilization, are a kind of comprehensive green surfactants of performance.
Oleth -10：With excellent decontamination, foaming, foam stabilizing, wetting, infiltration, solubilising, emulsification, dispersibility, especially
It is suitable for clear gel.
PEG-10 sojasterols：For emulsifying agent, softening agent, have it is good emulsify, disperse, solubilising, lubrication, decontamination energy
Power, has excellent calcium and magnesium dispersibility.It is oxidizable.
PEG-150 distearyl fat acid esters：It is soluble easily in water, there is excellent thickening property, be widely used in shampoo, liquid
The thickening of soap, liquid detergent, can dramatically increase the denseness of shampoo.
Oleyl alcohol eruciate：With excellent scattered, lubrication, emulsifying capacity, his structure and performance and natural Jojoba
Seed oil is very close, has the effect of outstanding skin or hair care and skin smooth, is usually used in personal-care supplies field.
Glycerine：With stronger hygroscopicity, skin moisture-keeping is moistened, be common softening agent, viscosity in cosmetics manufacture
Modifier and solvent.
Butanediol：Sense of touch is smooth, and property is stablized, easy to use, can obtain more soft skin sense in the product.
Propane diols：The viscosity and good hygroscopicity of propane diols, and it is nontoxic, thus in food, medicine and cosmetics industry
It is widely used as moisturizer, solubilizer, defoamer, anti-corrosive aids.
Isoprene：With excellent decontamination, scattered, solubilising power.It can be dissolved in water but also be dissolved in oil, and to skin
There are outstanding slipping and humidity-preserving type, there is outstanding antibiotic property, and it is preferable with the compatibility of grease.
1,2- hexylene glycols：Can efficiently permanent moisturizing, while also have the effect of antisepsis and sterilization.
Sensiva SC50：Formula moisturizing effect can be improved, while is had with soft and smooth skin sense.With deodorizing effect,
The growth and breeding of bacterium for causing peculiar smell can effectively be suppressed, while do not influence the skin flora beneficial to human body, so as to play
The effect that smell suppresses.
Polyethylene glycol：With good lubricity, moisture retention, dispersiveness, cementability, antistatic property and flexibility, nontoxic,
It is non-stimulated.
Jojoba seed oil：Main component is unsaturated advanced polyol fatty acid, is moistened very much, without any taste.Jojoba seed
Oil molecule arranges and the grease of human body is closely similar, easily permeates human skin, absorbability is good；Rich in abundant in jojoba seed oil
Vitamin and protein, moisture of skin can be maintained, have effects that nourish softening skin, take good care of baby's skin health.
Bisabolol：It is mainly used in skin sparing and nursing cosmetics, its stability is good, and absorbability is strong, has and relaxes
Slow skin, anti-inflammatory, antiallergy, anti-irritant and bacteriostasis.
Flos Chrysanthemi Indici extract：There is anti-bacteria and anti-virus, heat clearing and inflammation relieving, anti-oxidant prevention skin senescence.
Golden yellow camomile extract：With tranquilizing and allaying excitement, the effect of releiving, improve sensitivity, water shortage, the skin of dry decortication,
Increase skin elasticity, can also treat the scytitises such as skin eczema, running sore, acne, promote wound healing, and to conditioning sunburn and
The effect of.
Melilotus extract：Acted on antiviral, anti-inflammatory and anti-immunity.
Licorice：Acted on antiviral, anti-inflammatory and anti-immunity.
Camellia seed extract：It is a kind of sugared formula compound extracted from the seed of plant of theaceae, is a kind of natural non-
Ionic surfactant, have the function of it is good emulsify, disperse, foaming, moisten, and with anti-inflammatory, ease pain, impermeabilisation
Deng pharmacological action, it is widely used in washing, the production such as skin nursing, medicine, daily-use chemical industry industry.
Sodium glucoheptonate：The calcium and magnesium ion in the calcium and magnesium ion in water, especially hard water can be chelated, make calcium in water,
Magnesium ion will not the function of Surfactant have a negative impact.
Citric acid：Belong to one kind of tartaric acid, available for buffer solution is prepared, adjust pH, cutin renewal can be accelerated, be usually used in
Lotion, creams etc..
Boric acid：Its aqueous solution is in faintly acid, can be used as pH adjusting agent.
Malic acid：It is present in the fruits such as jejune apple, grape, hawthorn, also can be by fumaric acid through biofermentation
It is made, has special happy, soft tart flavour, pH value can be reduced, skin surface wrinkle can be removed, skin is become tender white, light
It is clean and flexible, there is antibacterial and oxidation resistant effect.
Sorbic acid：Sorbic acid can effectively inhibit the activity of mould, saccharomycete and aerobic bacteria, so as to reach effectively
Extend the holding time of food.Sorbic acid (potassium) belongs to acid preservative, still have in the food close to neutral (PH6.0-6.5) compared with
Good antisepsis.
Lysozyme：It is a kind of alkaline enzyme that can be hydrolyzed and polysaccharide is sticked in pathogenic bacteria.Mainly by destroying the N- second in cell membrane
β-Isosorbide-5-Nitrae glycosidic bond between acyl muramic acid and n-acetylglucosamine, makes the insoluble glutinous polysaccharide of cell membrane resolve into soluble sugar
Peptide, causes cell wall rupture content to escape and make bacterolysis.Lysozyme can also directly be tied with negatively charged virus protein
Close, form double salt with DNA, RNA, apoprotein, make virally inactivated.Therefore, which there is antibacterial, anti-inflammatory, antiviral etc. to make
With.Lysozyme is safe as preservative.Lysozyme is a kind of native protein, and property is very stable.
Protease：Protease can be used as skin conditioning agent.The component is that decomposing protein is Amino acid, and hydrolysate is in skin
Top layer forms one layer of amino acid and spreads out thing film, make skin keep wetting with it is smooth.
Lipase:It can accelerate lipolysis, also with Oily conditioning is made, temperature and pH be required more.
Amylase：The crude fibre in cosmetics and skin pore can be decomposed.A small amount of addition can have the volume of tightening skin at the same time
Effect.
Superoxide dismutase：The strong oxidizing property of free radical can make cell senescence, deformation, atrophy at the same time it also sink with pigment
The generation in shallow lake is related, and superoxide dismutase can be catalyzed the disproportionated reaction of ultra-oxygen anion free radical, so as to can effectively prevent skin
It is skin aging, nti-freckle, crease-resistant.
Co-Q10：It is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy, has and improve
Body immunity, strengthen the function such as anti-oxidant, anti-aging and enhancing human activity.It can go deep into cell at the same time, it is new to strengthen cell
Into metabolic function, consolidation binding ability between Polygonum Multiflorum Thunb Extract, on the other hand forms the net structure of elasticity, really repairing in epidermis
The wrinkle caused by fluid loss characteristics, and and then real moisture-keeping efficacy.
Collagen hydrolysate enzyme：Wrinkle can be reduced, desalinates scar and color spot, increases moisture of skin, is that one kind prevents skin
The enzyme for having special role of skin scar generation.
Parahydroxyacet-ophenone：From herbal medicine and molka, natural safety, has anti-irritant, has in terms of antiseptic property
Have extraordinary advantage, have it is anti-oxidant, remove free radical, delay the effect of light aging.
Ascorbic acid：There is anti-oxidant, Green Tea Extract, suppress the formation of TYR enzyme, so as to reach whitening, the work(of light spot
Effect；The effect of skin uvioresistant can be increased, collapsible pore, adjusts dermatoglyph, contributes to the increasing of skin corium collagen
It is raw, applied to personal-care supplies field.
Vitamin C dipalmitate：Properties with ascorbic acid, it is such as anti-oxidant, suppress the generation of melanin,
So as to reach the effect of whitening, and pore refining, while there is the emulsification relatively changed and dispersibility.
The selection of essence can select to meet as needed《GB/T22731-2008》Daily essence standard, international essence and flavoring agent
Association (IFRA), European Union's cosmetics instruction (26 essence anaphylactogens of European directive avoid) requirement, suitable essence can make baby
Have a bath when taking a shower with pleasant pure and fresh taste.
Shower cream provided in an embodiment of the present invention do not contain the different thiophene miaow quinoline ketone of methyl, nipagin esters etc. to skin irritation compared with
By force, easily draw the anti-corrosion composition of skin allergy volume contact dermatitis, and use it is pure natural, there is anti-inflammatory, is antibacterial, antiviral
The mixture of enzyme preparation or enzyme preparation and natural builds natural protective system, is not only able to play anti-well
Rotten effect, and it is gently non-stimulated to skin, it is safe, while the moisture of skin can be kept, it is not dry and astringent using rear skin
It is not tight.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
Shower cream provided in an embodiment of the present invention using it is pure natural, have anti-inflammatory, antibacterial, antiviral enzyme preparation or
The mixture of enzyme preparation and natural antioxidant builds natural protective system, is not only able to play effective anti-corrosion effect,
And it is gently non-stimulated to skin, it is safe.
Technical scheme and technique effect are described further below by way of specific embodiment.
Embodiment 1：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
10%th, cocounut oil acyl both sexes base diethyl acid disodium 4%), totally 14%；Nonionic surfactant (lauryl glucoside 6%, decyl
Glucoside 6%), totally 12%；Emulsifying agent (PEG-150 distearyl fat acid esters 5%)；Moisturizer (glycerine 2%, 1,2- hexylene glycols
0.4%), totally 2.4%；Skin conditioning agent (jojoba seed oil 0.5%, bisabolol 0.03%, Flos Chrysanthemi Indici extract 0.01%,
Golden yellow camomile extract 0.01%, melilotus extract 0.01%, licorice 0.01%, camellia seed extract
0.01%), totally 0.58%；Enzyme preparation (lysozyme 0.1%)；Antioxidant (parahydroxyacet-ophenone 0.5%)；Chelating agent (Portugal heptan
Sodium saccharate 0.12%)；PH adjusting agent (citric acid 0.2%)；Essence 0.15%, surplus are deionized water.
As the embodiment of the present invention, the preparation method of shower cream is as follows：
Step 1：Each component is weighed according to above-mentioned formula of bath cream, it is spare；
Step 2：The above-mentioned deionized water in part is added into ingredients pot, wherein, it is preferred that above-mentioned deionization can be added
The 60%-70% of water gross mass；
Step 3：Load weighted amphoteric surfactant, nonionic surfactant are added in ingredients pot, stirred to complete
Fully dissolved；
Step 4：By in load weighted skin conditioning agent, chelating agent input ingredients pot, 50 DEG C -60 DEG C are heated to, preferably
, it is heated to 50 DEG C, and stir to being completely dissolved；
Step 5：The deionized water of surplus is added in ingredients pot；
Step 6：It is to be cooled to be cooled to 20 DEG C~40 DEG C, it is preferred that when being cooled to 30 DEG C, natural antirot substance is added
In ingredients pot, stirring is to being completely dissolved.
Step 7：PH adjusting agent is added in ingredients pot, stirs evenly and adjusts pH value to 5.5, obtain shower cream finished product.
Embodiment 2：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
12%th, cocounut oil acyl both sexes base diethyl acid disodium 4%), totally 16%；Nonionic surfactant (lauryl glucoside 4%, decyl
Glucoside 6%), totally 10%；Emulsifying agent (PEG-150 distearyl fat acid esters 2.5%)；Moisturizer (glycerine 2.5%, 1,2- oneself two
Alcohol 1.5%), totally 4%；Skin conditioning agent (jojoba seed oil 0.5%, bisabolol 0.1%, Flos Chrysanthemi Indici extract 0.01%, gold
Yellow camomile extract 0.05%, melilotus extract 0.01%, licorice 0.05%, camellia seed extract 0.08%),
Totally 0.8%；Enzyme preparation (lysozyme 0.2%)；Antioxidant (parahydroxyacet-ophenone 0.8%)；Chelating agent (sodium glucoheptonate
0.05%)；PH adjusting agent (citric acid 0.1%)；Essence 0.1%, surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 3：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
10%th, cocounut oil acyl both sexes base diethyl acid disodium 5%), totally 15%；Nonionic surfactant (lauryl glucoside 6%, decyl
Glucoside 6%), totally 12%；Emulsifying agent (PEG-150 distearyl fat acid esters 4%)；Moisturizer (glycerine 2%, 1,2- hexylene glycols
1%), totally 3%；Skin conditioning agent (jojoba seed oil 2%, bisabolol 0.25%, Flos Chrysanthemi Indici extract 0.01%, golden yellow ocean
Flos Chrysanthemi extract 0.05%, melilotus extract 0.06%, licorice 0.05%, camellia seed extract 0.08%), altogether
2.5%；Enzyme preparation (lysozyme 0.5%)；Antioxidant (parahydroxyacet-ophenone 0.2%)；Chelating agent (sodium glucoheptonate
0.12%)；PH adjusting agent (citric acid 0.1%)；Essence 0.2%, surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 4：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
10%th, cocounut oil acyl both sexes base diethyl acid disodium 8%), totally 18%；Nonionic surfactant (lauryl glucoside 6%, decyl
Glucoside 8%), totally 14%；Emulsifying agent (PEG-150 distearyl fat acid esters 3%)；Moisturizer (glycerine 3%, 1,2- hexylene glycols
2%), totally 5%；Skin conditioning agent is (jojoba seed oil 0.25%, bisabolol 0.05%, Flos Chrysanthemi Indici extract 0.01%, golden yellow
Camomile extract 0.05%, melilotus extract 0.01%, licorice 0.05%, camellia seed extract 0.08%), altogether
0.5%；Enzyme preparation (lysozyme 0.2%)；Antioxidant (parahydroxyacet-ophenone 0.5%)；Chelating agent (sodium glucoheptonate
0.2%)；PH adjusting agent (citric acid 0.2%)；Essence 0.15%, surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 5：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
6%th, cocounut oil acyl both sexes base diethyl acid disodium 4%), totally 10%；Nonionic surfactant (lauryl glucoside 7%, decyl Portugal
Glucosides 8%), totally 15%；Emulsifying agent (PEG-150 distearyl fat acid esters 4%)；Moisturizer (glycerine 2.5%, 1,2- hexylene glycols
2.5%), totally 5%；Skin conditioning agent is (jojoba seed oil 0.8%, bisabolol 0.2%, Flos Chrysanthemi Indici extract 0.15%, golden yellow
Camomile extract 0.05%, melilotus extract 0.17%, licorice 0.05%, camellia seed extract 0.08%), altogether
1.5%；Enzyme preparation (lysozyme 0.5%)；Antioxidant (parahydroxyacet-ophenone 0.8%)；Chelating agent (sodium glucoheptonate
0.05%)；PH adjusting agent (citric acid 0.1%)；Essence 0.1%, surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 6：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (Cocoamidopropyl betaine
10%)；Nonionic surfactant (lauryl glucoside 11%)；Skin conditioning agent (jojoba seed oil 0.4%, bisabolol
0.2%th, camellia seed extract 0.1%), totally 0.7%；Enzyme preparation (lysozyme 0.4%, proteinase-10 .1%), totally 0.5%；Chelating
Agent (sodium glucoheptonate 0.1%)；PH adjusting agent (citric acid 0.15%), surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 7：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (stearamide propyl glycine betaine
8%th, Sodium Lauroamphoacetate 3%, Cocoamidopropyl betaine 3%), totally 14%；Nonionic surfactant (bay
Alcohol polyethers sulfosuccinate disodium 2%, coconut oil list isopropanol amide 8%), totally 10%；Skin conditioning agent (jojoba seed oil
0.3%th, Flos Chrysanthemi Indici extract 0.01%, golden yellow camomile extract 0.09%, melilotus extract 0.06%, licorice
0.06%), totally 0.52%；Enzyme preparation (lysozyme 0.1%)；Chelating agent (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid
0.05%th, sorbic acid 0.05%), totally 0.1%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 8：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium
6%th, sodium cocoyl glycinate 3%, Sodium Lauroamphoacetate 2%, lauryl betaine 3%, cocounut oil acyl both sexes base diethyl
Acid disodium 4%), totally 18%；Nonionic surfactant (coconut oil list isopropanol amide 5%, coconut monoethanol amide 10%),
Totally 15%；Skin conditioning agent (jojoba seed oil 2%, bisabolol 0.2%, melilotus extract 0.15%, licorice
0.03%th, camellia seed extract 0.12%), totally 2.5%；Enzyme preparation (lysozyme 0.14%, proteinase-10 .01%, lipase
0.01%th, amylase 0.01%, superoxide dismutase 0.01%, Co-Q10 0.01%, collagen hydrolysate enzyme
0.01%), totally 0.2%；Chelating agent (sodium glucoheptonate 0.2%)；PH adjusting agent (citric acid 0.14%, boric acid 0.06%), altogether
0.2%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 9：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (stearamide propyl glycine betaine
5%th, sodium cocoyl glycinate 4%, Cocoamidopropyl betaine 3%), totally 12%；(laruyl alcohol gathers nonionic surfactant
Ether sulfosuccinates disodium 6%, lauryl glucoside 6%), totally 12%；Skin conditioning agent (jojoba seed oil 1.5%, mother chrysanthemum
Flower extract 0.03%, golden yellow camomile extract 0.02%), totally 1.55%；Enzyme preparation (lysozyme 0.15%, lipase
0.1%), totally 0.25%；Antioxidant (parahydroxyacet-ophenone 0.5%)；Chelating agent (sodium glucoheptonate 0.08%)；PH adjusting agent
(malic acid 0.09%, sorbic acid 0.03%), totally 0.12%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 10：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (stearamide propyl glycine betaine
2%th, lauroyl oat amino acid sodium 2%, sodium cocoyl glycinate 2%, Sodium Lauroamphoacetate 8%, lauryl beet
Alkali 1%, Cocoamidopropyl betaine 2%, cocounut oil acyl both sexes base diethyl acid disodium 1%), totally 18%；Non-ionic surface active
Agent (laureth sulfosuccinate disodium 5%, coconut oil list isopropanol amide 10%), totally 15%；Skin conditioning agent is (red
Bisabol 0.15%, Flos Chrysanthemi Indici extract 0.15%, melilotus extract 0.05%, camellia seed extract 0.15%), altogether
0.5%；Enzyme preparation (amylase 0.02%, superoxide dismutase 0.06%, collagen hydrolysate enzyme 0.02%), totally 0.1%；
Antioxidant (parahydroxyacet-ophenone 0.35%, Vitamin C dipalmitate 0.4%), totally 0.75%；Chelating agent (glucoheptonic acid
Sodium 0.2%)；PH adjusting agent (citric acid 0.15%, boric acid 0.05%), totally 0.2%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 11：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium
3.5%th, lauryl betaine 2.5%, cocounut oil acyl both sexes base diethyl acid disodium 4%), totally 10%；Nonionic surfactant (the moon
Osmanthus base glucoside 10%)；Skin conditioning agent (jojoba seed oil 2.35%, bisabolol 0.11%, golden yellow camomile extract
0.01%th, melilotus extract 0.01%, licorice 0.01%, camellia seed extract 0.01%), totally 2.5%；Enzyme preparation
(lysozyme 0.1%, proteinase-10 .2%, lipase 0.1%, Co-Q10 0.05%, collagen hydrolysate enzyme 0.05%), altogether
0.5%；Antioxidant (ascorbic acid 0.25%, Vitamin C dipalmitate 0.95%), totally 1.2%；Chelating agent (glucoheptose
Sour sodium 0.05%)；PH adjusting agent (boric acid 0.08%, sorbic acid 0.02%), totally 0.1%；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 12：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (stearamide propyl glycine betaine
3%th, sodium cocoyl glycinate 2%, Cocoamidopropyl betaine 5%, cocounut oil acyl both sexes base diethyl acid disodium 5%), altogether
15%；Nonionic surfactant (coconut monoethanol amide 3%, lauryl glucoside 9%), totally 12%；Skin conditioning agent is (suddenly
Bar seed oil 1.5%, bisabolol 1% suddenly), totally 2.5%；Enzyme preparation (lysozyme 0.35%, amylase 0.1%, Co-Q10
0.05%), totally 0.5%；Antioxidant (parahydroxyacet-ophenone 1%, ascorbic acid 0.2%), totally 1.2%；Chelating agent (glucoheptose
Sour sodium 0.12%)；PH adjusting agent (citric acid 0.1%)；Surplus is deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
Embodiment 13：
A kind of formula of shower cream is as follows：By weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium
6%th, Cocoamidopropyl betaine 7%), totally 13%；Nonionic surfactant (Plantacare 818 13%)；Emulsifying agent (oil
Alcohol polyethers -102%, PEG-150 distearyl fat acid esters 3%), totally 5%；Moisturizer (glycerine 3%)；Skin conditioning agent (Jojoba
Seed oil 1%, melilotus extract 0.04%, camellia seed extract 0.06%), totally 1.1%；Enzyme preparation (lipase 0.2%)；It is anti-
Oxidant (parahydroxyacet-ophenone 0.9%)；Chelating agent (sodium glucoheptonate 0.07%)；PH adjusting agent (citric acid 0.14%, apple
Acid 0.06%), totally 0.2%；Essence 0.15%, surplus are deionized water.
In embodiments of the present invention, the preparation method of shower cream is in the same manner as in Example 1.
It should be noted that in embodiments of the present invention, when natural antirot substance is enzyme preparation, which is bacteriolyze
Enzyme and protease, lipase, amylase, superoxide dismutase, Co-Q10 either one kind in collagen hydrolysate enzyme or
At least two mixture.For convenience of description, above embodiments only show several optimum organization modes therein.In reality
Application in, can arbitrarily select protease, lipase, amylase, superoxide dismutase, Co-Q10 or collagen water
Therein a kind of or at least two the mixture for solving enzyme forms compound with lysozyme, protective system is built, as long as keeping
The compound accounts for 0.1%-0.5% in formula, does not just enumerate herein one of the various
Combination.
Based on it is above-mentioned identical the reasons why, involved in the embodiment of the present invention when natural antirot substance is enzyme preparation and antioxygen
During the mixture of agent, wherein, enzyme preparation is lysozyme, protease, lipase, amylase, superoxide dismutase, coenzyme
Q10 either a kind of in collagen hydrolysate enzyme or at least two mixture；Antioxidant is parahydroxyacet-ophenone, or
The mixture of the one of which of parahydroxyacet-ophenone and ascorbic acid or Vitamin C dipalmitate.The amphoteric surface lives
Property agent for stearamide propyl glycine betaine, lauroyl oat amino acid sodium, sodium cocoyl glycinate, lauroyl both sexes guanidine-acetic acid
Sodium, lauryl betaine, Cocoamidopropyl betaine either one kind in cocounut oil acyl both sexes base diethyl acid disodium or at least
Two kinds of mixture；The nonionic surfactant is laureth sulfosuccinate disodium, coconut oil list isopropanol
One or two kinds of mixture in acid amides, coconut monoethanol amide, lauryl glucoside or Plantacare 818；The breast
Agent is oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters or one kind in oleyl alcohol eruciate or
The mixture that two kinds of person；The moisturizer is glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, ethylhexyl are sweet
One or two kinds of mixture in oil or polyethylene glycol；The skin conditioning agent is jojoba seed oil, bisabolol, open country
At least three kinds in chrysanthemum extract, golden yellow camomile extract, melilotus extract, licorice or camellia seed extract
Mixture；The pH adjusting agent is one or two kinds of mixture in citric acid, boric acid, malic acid or sorbic acid.
The various combinations of these above-mentioned components also do not enumerate herein.
In order to further illustrate the security and using effect of shower cream provided in an embodiment of the present invention, below by way of experiment
Example further illustrates the beneficial effect of shower cream provided in an embodiment of the present invention：
Experiment one：Preservative detects
1st, test specimen：Shower cream sample provided in an embodiment of the present invention.
2nd, test method：With reference to the test method and SN/T1786- in cosmetics safety technical specification (version in 2015)
Measure-liquid chromatography of triclosan and triclocarban tests sample in 2006 inlet and outlet cosmetics.
3rd, result of the test：Table 1 below is referred to, wherein, expression is not detected is less than detection limit.
Table 1
From the testing result of table 1 as can be seen that without methyl chloride isothiazoline in shower cream provided in an embodiment of the present invention
The Determination of common preservatives such as ketone, methylisothiazolinone, Phenoxyethanol, nipagin esters.
Wherein, in shower cream provided in an embodiment of the present invention, the main component for playing antisepsis for natural lysozyme and/
Or natural (parahydroxyacet-ophenone).Lysozyme is a kind of native protein, and property is very stable, have antibacterial, anti-inflammatory,
Antiviral to wait effect, lysozyme is safe as preservative.Parahydroxyacet-ophenone is the natural peace from herbal medicine and molka
Entirely, there is anti-irritant, there is extraordinary advantage in terms of antiseptic property.Shower cream provided in an embodiment of the present invention is preferably adopted
Natural protective system is built jointly with lysozyme and parahydroxyacet-ophenone, in the synergistic effect of lysozyme and parahydroxyacet-ophenone
Under, good anti-corrosion effect can be reached.
Experiment two：Preservative efficacy testing
1st, test specimen：Shower cream sample provided in an embodiment of the present invention；Experimental bacteria is Escherichia coli ATCC 25922, gold
Staphylococcus aureus ATCC 6538, pseudomonas aeruginosa ATCC 9027, Candida albicans ATCC 10231.
2nd, test method：Microbiology challenge test method.
3rd, result evaluation：Using《European Pharmacopoeia》Result evaluation standard this result of the test is evaluated, have
Body refers to table 2 below.
Table 2
From 4 kinds of experimental bacterias of results showed that of upper table 2 in the 7th day when (1 week) total plate count decline 100%, to
Without growth at 28 days, judge to test by challenge, inhibitor effectiveness is good, i.e., the anti-corrosion of shower cream provided in an embodiment of the present invention
Work well.
Experiment three：Acute oral toxicity test
1st, the preparation of experimental liquid：25 grams of shower cream sample to the numbering for weighing the offer of embodiment 1~13 respectively is No. 1-13
Volumetric flask in, add ultra-pure water and be settled to 100mL, mixing is used as experimental liquid.
Trial test：Oral gavage experiment is carried out to experimental animal using the experimental liquid of 5000mg/kg body weight doses, is not found
There is death in experimental animal, therefore formal test design dosage is 5000mg/kg weight.
Formal test：140 healthy, 18~20 grams of weight SPF level kunming mices are chosen, stochastic averagina is divided into 14
Group, every group each 10, half male and half female, and it is 1~14 to number, wherein, group 1 is blank control group, by the amount of 0.2mL/10g weight
Ultra-pure water is given with oral 1 gavage of gastric perfusion needle；Group 2~groups 14 are respectively by oral 1 time of the amount gastric perfusion needle of 0.2mL/10g weight
Gavage gives 1~No. 13 experimental liquid, that is, organizes 2 and give No. 1 experimental liquid, group 3 gives No. 2 experimental liquids, and group 4 gives No. 3 experimental liquids, group
5 give No. 4 experimental liquids ..., and group 14 gives No. 13 experimental liquids.When each group animal fasting 16 is small before gavage, freely drink
Water, gives normal diet, Routine Management after gavage；Identical number of days is raised, observes the poisoning symptom of mouse and dead feelings daily
Condition, after the completion of experiment in 14 days, data statistics is carried out to result of the test.
Wherein, during this experiment, it is poisoned during finger to finger test, mouse occurs trembling, twitches, salivates, diarrhea, drowsiness
Or the symptom such as stupor.Oral toxicity classification is as shown in table 3 below：
Table 3
| LD50(mg/Kg) | ≤50 | 51~500 | 501~5000 | ＞ 5000 |
| Toxicity grading | High poison | Medium poison | Low toxicity | It is actual nontoxic |
During whole experiment, the diet activity of each group animal subject is normal, has no obvious poisoning symptom and death.Cause
This, its mouse oral acute toxicity LD50 of shower cream provided in an embodiment of the present invention>5000mg/kg weight, security are good.
Experiment four：Safe and healthy detection
1st, test specimen:Shower cream sample provided in an embodiment of the present invention.
2nd, test method：With reference to cosmetics safety technical specification (version in 2015)；Detection project：Microorganism and health refer to
Mark.
3rd, result of the test：Table 4 below and table 5 are referred to, wherein, expression is not detected is less than detection limit.
The microorganism detection result of 4 shower cream of table
| Inspection project | Inspection result | Limit value |
| Total plate count (CFU/g) | ＜ 10 | ≤500 |
| Yeast and mold (CFU/g) | ＜ 10 | ≤100 |
| Heat-resisting coliform (/g) | Do not detect | It must not detect |
| Staphylococcus aureus (/g) | Do not detect | It must not detect |
| Pseudomonas aeruginosa (/g) | Do not detect | It must not detect |
The hygiene inspection result of 5 shower cream of table
| Inspection project | Unit | Inspection result | The method of inspection | Method concentrations | Limit value |
| Mercury | mg/kg | Do not detect | Hydride generation atomic fluorescence photometry | 0.1 | ≤1 |
| Lead | mg/kg | Do not detect | Atomic absorption spectrophotometry | 5 | ≤10 |
| Arsenic | mg/kg | Do not detect | Hydride generation atomic fluorescence photometry | 0.5 | ≤2 |
| Cadmium | mg/kg | Do not detect | Atomic absorption spectrophotometry | 0.59 | ≤5 |
| Dioxane | mg/kg | Do not detect | Gas chromatography-mass spectrography | 1.0 | ≤30 |
As can be seen that the safe and healthy finger of shower cream provided in an embodiment of the present invention from upper table 4 and the inspection result of table 5
Mark meets the safe and healthy standard of cosmetics.
Experiment five：The residual test of agriculture
1st, test sample：Shower cream sample provided in an embodiment of the present invention.
2nd, test method and evaluation of result standard：Third party authoritative institution laboratory internal detection method.
3rd, result of the test：Table 6 below is referred to, wherein, expression is not detected is less than test limit.
Table 6
It can be seen that from the test result of upper table 6 in shower cream provided in an embodiment of the present invention without 30 agricultures in cosmetics
Medicine remains, and the security of product is good.
Experiment six：Ocular irritation/erosion test
1st, test specimen：Shower cream sample provided in an embodiment of the present invention.
2nd, test method：SN/T 2329-2009 cosmetics eye irritation/corrosive chick chorioallantoic membrane experiment.
3rd, evaluation of test result standard：Standards of grading are stimulated to be divided into level below：IS ＜ 1 are nonirritant；1≤IS ＜ 5
For subexcite；5≤IS ＜ 9 are moderate irritation；IS >=10 are strong and stimulating/corrosivity.
4th, result of the test：Through overtesting, the stimulation scoring for the shower cream sample that 1-13 of the embodiment of the present invention is provided is IS
＜ 1, i.e., shower cream provided in an embodiment of the present invention are gently nonirritant to eye.
Experiment seven：Skin irritation test
(1) skin closure type patch test
1st, test specimen：Shower cream sample provided in an embodiment of the present invention.
2nd, test method:From a certain 28 volunteers of regional choice, the age of volunteer, body was good between 20~45 years old
Health, in the recent period non-drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 14 groups at random,
Every group of two people.Wherein, group 1 is blank control group, and the small interior of spot examination device does not place any material, spot is tried the low sensitization glue of device
Band is pasted on the back of volunteer or forearm bends side, is gently pressed with palm and is allowed to equably stick on the skin；Group 2~groups 14 with
The processing method of group 1 is identical, unlike：The stern protection cream provided added with the 0.025mL embodiment of the present invention 1~13 is put into respectively
The small interior of spot examination device；I.e. group 2 it is corresponding be the embodiment of the present invention 1 provide stern protection cream, group 3 it is corresponding be the embodiment of the present invention 2
The stern protection cream of offer, it is stern protection cream ... that the embodiment of the present invention 3 provides that group 4 is corresponding, and corresponding group 14 is this
The stern protection cream that inventive embodiments 13 provide.When each group test duration 24 is small, 48 it is small when after, remove spot examination device after 30min, treat impression
After disappearance, observation sticks the response situation and record of place's skin.
Wherein, skin closure type patch test dermoreaction grade scale see the table below 7.
Table 7
During whole experiment, the dermoreaction of the recipient site of the subject of group 1- groups 14 is negative.By
This, which can be seen that shower cream provided in an embodiment of the present invention, will not cause the allergy and stimulate the reaction of skin, and security is good.
(2) repeatability is opening smears experiment
1st, test specimen:Shower cream sample provided in an embodiment of the present invention.
2nd, test method：From a certain region select 28 volunteers, the age of volunteer between 20-45 Sui, body
Health, in the recent period non-drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 14 at random
Group, every group of two people.Wherein, group 1 is blank control group, is bent using forearm and is used as recipient site, 3 × 3cm of area2, recipient site
Drying is kept, avoids contact with before tested and during by gesture other external preparations, with ultra-pure water 0.05 ± 0.005g/ times, equably
Smear recipient site；Group 2~groups 14 are respectively test group, unlike group 1：There is provided using the embodiment of the present invention 1~13
Stern protection cream sample equably smears recipient site 0.05 ± 0.005g/ times；Wherein, group 2 corresponds to the shield that the embodiment of the present invention 1 provides
Stern frost sample, group 3 correspond to the stern protection cream sample that the embodiment of the present invention 2 provides, and group 4 corresponds to the hip pad that the embodiment of the present invention 3 provides
White sample ... and so on, group 14 corresponds to the stern protection cream sample that the embodiment of the present invention 13 provides.Each group carries out 2 times uniformly daily
Recipient site is smeared on ground, and long run test completes experiment after 7 days, observe the dermoreaction situation of recipient site of subject daily simultaneously
Record.During experiment, during if there is more than 3 points in such as table 8 below of dermoreaction situation, it can stop continuing to test
And record result.
Wherein, table 8 smears experiment dermoreaction judgment criteria table for skin repeatability is opening.
Table 8
During whole experiment, the dermoreaction of the recipient site of the subject of group 1~groups 14 is negative.By
This, which can be seen that shower cream provided in an embodiment of the present invention, will not cause the allergy and stimulate the reaction of skin, and security is good.
Experiment eight：Using effect contrast test
1st, test specimen：The shower cream and contrast product (Sheda baby's bubble bath that the embodiment of the present invention 1~13 provides
(Germany), the red tender shower cream of baby elephant child (China), shellfish parent baby bath dew (China), Johnson ＆ Johnson's babymilk shower cream
(China)).
2nd, test method：85 people of subject at 18~25 years old age is randomly choosed, and stochastic averagina is divided into 17 groups, every group 5
People, and numbering 1~17, wherein, group 1~groups 4 are control group 1~groups 4, are respectively Sheda baby bubble bath (Germany) control group
1st, red baby elephant child tender shower cream (China) control group 2, shellfish parent baby bath dew (China) control group 3, Johnson ＆ Johnson baby ox
Milk shower cream (China) control group 4；Group 5~groups 17 are respectively the experiment for the shower cream sample that the embodiment of the present invention 1~13 provides
Group, that is, organize the 5 shower cream test groups provided for the embodiment of the present invention 1, the shower cream examination that group 6 provides for the embodiment of the present invention 2
Test group, the shower cream test groups ... that group 7 provides for the embodiment of the present invention 3 and so on, group 17 is the embodiment of the present invention 13
The shower cream test group of offer.
During experiment, the arm of fixed subject, and at the beginning of the initial parameter index with skinanalysis apparatus measurement subject's arm
Initial value (moisture, oil)；Each test specimen of equivalent is taken on the arm of each subject, then to add a small amount of water to smear uniform, gently
After light rubbing 3 minutes, rinsed well with clear water；After 2 minutes, skin naturally dry, subject's arm is measured with skinanalysis apparatus
Each parameter index value of arm simultaneously records.
3rd, result of the test：Table 9 below is referred to, wherein, oil percentage=((wash rear oil-wash preceding oil) × 100%)/wash
Preceding oil；Percent water rate=((wash rear moisture-wash preceding moisture) × 100%)/wash preceding moisture.
Table 9
As can be seen that using after shower cream provided in an embodiment of the present invention from the result of the test of upper table 9, its oil subtracts
Contrast product is considerably less than on a small quantity, and the incrementss of moisture are significantly more than contrast product, i.e., it is provided in an embodiment of the present invention to wash one's hair
Bath lotion can effectively keep the moisture of skin, while salubrious non-greasy after use.Wherein, test effect is optimal to organize 7, i.e.,
The shower cream product that the embodiment of the present invention 3 is provided, its formulation product can keep the moisture of skin, and the increasing of oil well
Add rate relatively low, salubrious experience sense can be brought to user, the symptom such as advantageously reduce scaly dry skin, itch.
Shower cream provided in an embodiment of the present invention do not contain the different thiophene miaow quinoline ketone of methyl, nipagin esters etc. to skin irritation compared with
By force, easily draw the anti-corrosion composition of skin allergy volume contact dermatitis, and use it is pure natural, there is anti-inflammatory, is antibacterial, antiviral
The mixture of enzyme preparation or enzyme preparation and natural builds natural protective system, is not only able to play anti-well
Rotten effect, and it is gently non-stimulated to skin, it is safe, while the moisture of skin can be kept, it is not dry and astringent using rear skin
It is not tight.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
- A kind of 1. shower cream, it is characterised in that by weight, including following component：Amphoteric surfactant：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Natural antirot substance：0.1%~1.7%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.
- 2. shower cream as claimed in claim 1, it is characterised in that by weight, including following component：Amphoteric surfactant：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Enzyme preparation：0.1%~0.5%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the enzyme preparation be lysozyme and protease, lipase, amylase, superoxide dismutase, Co-Q10 or A kind of in collagen hydrolysate enzyme or at least two mixture.
- 3. shower cream as claimed in claim 1, it is characterised in that by weight, including following component：Amphoteric surfactant：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Enzyme preparation：0.1%~0.5%；Antioxidant：0.5%~1.2%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the enzyme preparation is lysozyme, protease, lipase, amylase, superoxide dismutase, Co-Q10 or glue A kind of in former proteolytic enzyme or at least two mixture；The antioxidant is parahydroxyacet-ophenone, either two palmitic acid of parahydroxyacet-ophenone and ascorbic acid or ascorbic acid The mixture of the one of which of ester.
- 4. shower cream as claimed in claim 1, it is characterised in that by weight, including following component：Amphoteric surfactant：15%；Nonionic surfactant：12%；Skin conditioning agent：2.5%；Enzyme preparation：0.5%；Antioxidant：1.2%；Chelating agent：0.12%；PH adjusting agent：0.1%；Surplus is deionized water.
- 5. shower cream as claimed in claim 1, it is characterised in that by weight, including following component：Amphoteric surfactant：10%~18%；Nonionic surfactant：10%~15%；Skin conditioning agent：0.5%~2.5%；Natural antirot substance：0.1%~1.7%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Emulsifying agent：2.5%~5%；Moisturizer：2.4~5%；Essence：0.1%~0.2%；Surplus is deionized water.
- 6. shower cream as claimed in claim 5, it is characterised in that by weight, including following component：Amphoteric surfactant：15%；Nonionic surfactant：12%；Skin conditioning agent：2.5%；Enzyme preparation：0.5%；Antioxidant：1.2%；Chelating agent：0.12%；PH adjusting agent：0.1%；Emulsifying agent：4%；Moisturizer：3%；Essence：0.2%；Surplus is deionized water.
- 7. shower cream as claimed in claim 5, it is characterised in that the amphoteric surfactant is stearamide propyl beet Alkali, lauroyl oat amino acid sodium, sodium cocoyl glycinate, Sodium Lauroamphoacetate, lauryl betaine, coconut oleoyl amine Propyl betaine either a kind of in cocounut oil acyl both sexes base diethyl acid disodium or at least two mixture；The nonionic surfactant is laureth sulfosuccinate disodium, coconut oil list isopropanol amide, cocounut oil One or two kinds of mixture in single ethanol amide, lauryl glucoside or Plantacare 818；The emulsifying agent is oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters or oleyl alcohol eruciate In one or two kinds of mixture；The moisturizer is glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, Sensiva SC50 or poly- second two One or two kinds of mixture in alcohol；The skin conditioning agent is jojoba seed oil, bisabolol, Flos Chrysanthemi Indici extract, golden yellow camomile extract, sweet clover At least three kinds of mixture in extract, licorice or camellia seed extract；The chelating agent is sodium glucoheptonate；The pH adjusting agent is one or two kinds of mixture in citric acid, boric acid, malic acid or sorbic acid.
- 8. shower cream as claimed in claim 7, it is characterised in that the amphoteric surfactant is cocamidopropyl propyl amide beet The mixture of alkali and cocounut oil acyl both sexes base diethyl acid disodium；The nonionic surfactant is lauryl glucoside and the mixture of Plantacare 818；The emulsifying agent is PEG-150 distearyl fat acid esters；The moisturizer is glycerine and the mixture of 1,2- hexylene glycols；The skin conditioning agent is jojoba seed oil, bisabolol, Flos Chrysanthemi Indici extract, golden yellow camomile extract, sweet clover The mixture of extract, licorice and camellia seed extract；The pH adjusting agent is citric acid.
- 9. shower cream as claimed in claim 5, it is characterised in that the amphoteric surfactant includes following material and weight Percentage：Cocoamidopropyl betaine 10% and cocounut oil acyl both sexes base diethyl acid disodium 5%；The nonionic surfactant includes following material and percentage by weight：Lauryl glucoside 6% and Plantacare 818 6%；The skin conditioning agent includes following material and percentage by weight：Jojoba seed oil 2%, bisabolol 0.25%, mother chrysanthemum Flower extract 0.01%, golden yellow camomile extract 0.05%, melilotus extract 0.06%, licorice 0.05% and Camellia seed extract 0.08%；The enzyme preparation includes following material and percentage by weight：Lysozyme 0.5%；The antioxidant includes following material and percentage by weight：Parahydroxyacet-ophenone 0.2%；The chelating agent includes following material and percentage by weight：Sodium glucoheptonate 0.12%；The pH adjusting agent includes following material and percentage by weight：Citric acid 0.1%；The emulsifying agent includes following material and percentage by weight：PEG-150 distearyl fat acid esters 4%；The moisturizer includes following material and percentage by weight：Glycerine 2% and 1,2- hexylene glycols 1%；Essence：0.2%；Surplus is deionized water.
- 10. the preparation method of the shower cream as described in claim 1-9 any one, it is characterised in that include the following steps：Formula according to the shower cream as described in any one in claim 1~9 weighs each component, spare；The part deionized water is added into ingredients pot；The amphoteric surfactant, nonionic surfactant are added in the ingredients pot, stirring is to being completely dissolved；The skin conditioning agent, chelating agent are put into the ingredients pot, are heated to 50 DEG C -60 DEG C, stirring is to being completely dissolved；The deionized water of surplus is added in the ingredients pot；It is to be cooled to add the natural antirot substance in the ingredients pot when being cooled to 20 DEG C -40 DEG C, stir to completely molten Solution；The pH adjusting agent is added in the ingredients pot, stirs evenly and adjusts pH value to 5.5, obtain the shower cream.
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| CN201711420370.0A CN107998028A (en) | 2017-12-25 | 2017-12-25 | A kind of shower cream and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108524327A (en) * | 2018-05-25 | 2018-09-14 | 珠海伊斯佳科技股份有限公司 | A kind of shower cream and preparation method thereof |
| CN108685720A (en) * | 2018-07-25 | 2018-10-23 | 啵噜噜（广州）婴儿用品科技有限公司 | A kind of baby's shampoo used also as bath lotion |
| CN109248122A (en) * | 2018-11-09 | 2019-01-22 | 厦门舒菲娅化妆品有限公司 | A kind of shampoo used also as bath lotion and preparation method thereof |
| CN109276494A (en) * | 2018-09-30 | 2019-01-29 | 江门职业技术学院 | A kind of anti-inflammatory and antipruritic shower gel and preparation method thereof |
| CN110354036A (en) * | 2019-07-25 | 2019-10-22 | 重庆菩璞生物科技有限公司 | A kind of composition and its preparation method and application being used to prepare coptis bath foam |
| CN111067814A (en) * | 2019-10-30 | 2020-04-28 | 广州市浪奇实业股份有限公司 | Antibacterial skin cleaning product |
| CN111937874A (en) * | 2020-08-09 | 2020-11-17 | 北京美科兴业生物科技有限公司 | A p-hydroxyacetophenone solution composition containing stabilizer |
| CN114469804A (en) * | 2022-01-26 | 2022-05-13 | 南昌大学第一附属医院 | Method for preparing skin cream |
| CN115737459A (en) * | 2022-11-17 | 2023-03-07 | 广州市雅创化妆品有限公司 | Body cleaning composition with moisturizing, moistening and skin nourishing effects and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524327A (en) * | 2018-05-25 | 2018-09-14 | 珠海伊斯佳科技股份有限公司 | A kind of shower cream and preparation method thereof |
| CN108685720A (en) * | 2018-07-25 | 2018-10-23 | 啵噜噜（广州）婴儿用品科技有限公司 | A kind of baby's shampoo used also as bath lotion |
| CN109276494A (en) * | 2018-09-30 | 2019-01-29 | 江门职业技术学院 | A kind of anti-inflammatory and antipruritic shower gel and preparation method thereof |
| CN109248122A (en) * | 2018-11-09 | 2019-01-22 | 厦门舒菲娅化妆品有限公司 | A kind of shampoo used also as bath lotion and preparation method thereof |
| CN110354036A (en) * | 2019-07-25 | 2019-10-22 | 重庆菩璞生物科技有限公司 | A kind of composition and its preparation method and application being used to prepare coptis bath foam |
| CN111067814A (en) * | 2019-10-30 | 2020-04-28 | 广州市浪奇实业股份有限公司 | Antibacterial skin cleaning product |
| CN111937874A (en) * | 2020-08-09 | 2020-11-17 | 北京美科兴业生物科技有限公司 | A p-hydroxyacetophenone solution composition containing stabilizer |
| CN114469804A (en) * | 2022-01-26 | 2022-05-13 | 南昌大学第一附属医院 | Method for preparing skin cream |
| CN115737459A (en) * | 2022-11-17 | 2023-03-07 | 广州市雅创化妆品有限公司 | Body cleaning composition with moisturizing, moistening and skin nourishing effects and preparation method thereof |
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Application publication date: 20180508 |