CN105766935B - A kind of bactericidal composition and its application of Fluoxastrobin, difenoconazole and hexaconazole - Google Patents
A kind of bactericidal composition and its application of Fluoxastrobin, difenoconazole and hexaconazole Download PDFInfo
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- CN105766935B CN105766935B CN201610217463.2A CN201610217463A CN105766935B CN 105766935 B CN105766935 B CN 105766935B CN 201610217463 A CN201610217463 A CN 201610217463A CN 105766935 B CN105766935 B CN 105766935B
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- Prior art keywords
- fluoxastrobin
- difenoconazole
- hexaconazole
- agent
- bactericidal composition
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- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 239000005760 Difenoconazole Substances 0.000 title claims abstract description 42
- 239000005784 Fluoxastrobin Substances 0.000 title claims abstract description 42
- BQYJATMQXGBDHF-UHFFFAOYSA-N difenoconazole Chemical compound O1C(C)COC1(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)Cl)CN1N=CN=C1 BQYJATMQXGBDHF-UHFFFAOYSA-N 0.000 title claims abstract description 42
- UFEODZBUAFNAEU-NLRVBDNBSA-N fluoxastrobin Chemical compound C=1C=CC=C(OC=2C(=C(OC=3C(=CC=CC=3)Cl)N=CN=2)F)C=1C(=N/OC)\C1=NOCCO1 UFEODZBUAFNAEU-NLRVBDNBSA-N 0.000 title claims abstract description 42
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 32
- STMIIPIFODONDC-UHFFFAOYSA-N 2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(O)(CCCC)CN1C=NC=N1 STMIIPIFODONDC-UHFFFAOYSA-N 0.000 title claims abstract description 28
- 239000004480 active ingredient Substances 0.000 claims abstract description 23
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- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 description 7
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- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 3
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- 241001157813 Cercospora Species 0.000 description 3
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 3
- 206010039509 Scab Diseases 0.000 description 3
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- 239000003899 bactericide agent Substances 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 3
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 2
- 229920001732 Lignosulfonate Polymers 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 229930040373 Paraformaldehyde Natural products 0.000 description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 2
- 229930182558 Sterol Natural products 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 125000001931 aliphatic group Chemical group 0.000 description 2
- 125000003368 amide group Chemical group 0.000 description 2
- 239000000440 bentonite Substances 0.000 description 2
- 229910000278 bentonite Inorganic materials 0.000 description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
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- 125000005375 organosiloxane group Chemical group 0.000 description 2
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
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- 150000003852 triazoles Chemical class 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- 241000235349 Ascomycota Species 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
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- 102000018832 Cytochromes Human genes 0.000 description 1
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- 206010059866 Drug resistance Diseases 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 241000221785 Erysiphales Species 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 229930182692 Strobilurin Natural products 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 150000004996 alkyl benzenes Chemical group 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
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- 239000002872 contrast media Substances 0.000 description 1
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- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000017858 demethylation Effects 0.000 description 1
- 238000010520 demethylation reaction Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
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- 239000003112 inhibitor Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- BSDQITJYKQHXQR-UHFFFAOYSA-N methyl prop-2-eneperoxoate Chemical compound COOC(=O)C=C BSDQITJYKQHXQR-UHFFFAOYSA-N 0.000 description 1
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- 239000007787 solid Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000004562 water dispersible granule Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention discloses a kind of bactericidal composition and its application of Fluoxastrobin, difenoconazole and hexaconazole, and using Fluoxastrobin, difenoconazole and hexaconazole as active ingredient, the weight percentage of Fluoxastrobin, difenoconazole and hexaconazole is the bactericidal composition：Fluoxastrobin 1 30%, difenoconazole 1 25%, hexaconazole 1 10%; the composition stability is good; the advantage of three kinds of active ingredient can effectively be played; with apparent synergistic effect; to nearly all fungal disease in wheat, corn, watermelon rice and peanut and other crops; especially control of plant disease effect caused by basidiomycetes, Fungi Imperfecti, oomycetes and sac fungus is protruded, the prevention spectrum of the composition is wider, while having protection and therapeutic effect.In addition, this three compounding can also reduce the dosage of active ingredient, delay pathogen to generate resistance to it, be effectively protected natural enemy, there is important economic implications, environment protection significance and ecological significance for the integrated control of harmful organism.
Description
Technical field
The invention discloses a kind of agriculture chemical compounding bactericidal composition, especially a kind of Fluoxastrobin, difenoconazole and own azoles
The bactericidal composition of alcohol and its application.
Background technology
Fluoxastrobin, is methoxy acrylate (Strobilurin) class sterilization pesticide, and active compound appearance is off-white color to yellow
Solid（Content is higher, fineness is better, color is more shallow）, have the characteristics that efficiently, wide spectrum, mainly by with cell color on mitochondria
The sites Qo of plain b combine, and block the electronics transfer between cytochromes, the breathing of mitochondria is inhibited to play a role, destroy disease
The energy of bacterium synthesizes.The product is to almost all of mycota（Ascomycotina, Basidiomycotina, Mastigomycotina and partly know
Bacterium subphylum）Disease such as powdery mildew, rust, banded sclerotial blight etc. have good activity.
Difenoconazole is the interior suction wide-spectrum bactericide that safety is relatively high in triazole bactericidal agent, has protection and controls
Treatment acts on, and wide sterilization spectrum, lasting period are long, and difenoconazole can inhibit the wheat of fungi as all triazole bactericidal agents
The biosynthesis of angle sterol.Active compound is grayish white powdery object, and 78.6 DEG C of fusing point is widely used in the crops such as fruit tree, vegetables, can have
The diseases such as effect prevention scab, anthrachose of grape and white rot.
Hexaconazole, sterol demethylation inhibitors, active compound are ecru loose powder, to fungi especially Basidiomycota and
Disease caused by Ascomycota has the protection and therapeutic effect of broad spectrum activity.Hexaconazole is mainly by destroying and preventing the cell of germ
The biosynthesis of film important composition ingredient ergosterol causes cell membrane that cannot be formed, to keep germ dead, have interior suction,
Protection and therapeutic activity.
The study found that various plants germ produces resistance to Fluoxastrobin, continuous administration 2 times or more, to harmful organism
Control effect decreased significantly；And Fluoxastrobin is applied with after difenoconazole complex preparation, control effect is obviously improved.Cause
This, agriculture chemical compounding can not only delay harmful organism to the generation of pesticide drug resistance, be effectively protected natural enemy, and have new increasing
Effect acts on.Currently, have no Fluoxastrobin, difenoconazole and hexaconazole this three complex preparation related report.
Invention content
The purpose of the present invention is to provide the bactericidal composition of a kind of Fluoxastrobin, difenoconazole and hexaconazole, the combinations
Object not only ensure that the chemical stability and physical behavior of Fluoxastrobin, difenoconazole and hexaconazole, but also delay harmful organism pair
The development of pesticide resistance, and excellent synergistic effect has been shown in field control effectiveness test, it is a kind of excellent agriculture chemical compounding
Product.
The technical solution adopted by the present invention is as follows：
A kind of bactericidal composition, the bactericidal composition active ingredient are Fluoxastrobin, difenoconazole and hexaconazole, phonetic bacterium
The weight percentage of ester, difenoconazole and hexaconazole in bactericidal composition is：Fluoxastrobin 1-30%, difenoconazole 1-
25%, hexaconazole 1-10%.
Further, in the bactericidal composition, the mass ratio of Fluoxastrobin, difenoconazole and hexaconazole is 1-8:1-6:1,
Preferably 3.93-4.1:2.47-2.55:1.
Further, in the bactericidal composition, content of three kinds of active ingredient summations in bactericidal composition is 9-
50wt%, preferably in 30-35wt%.
Further, further include auxiliary agent other than active ingredient in the bactericidal composition, the auxiliary agent is wetting agent, divides
Powder, antifoaming agent, antifreezing agent, thickener and preservative, the content of auxiliary agent are the 1-30wt% of bactericidal composition, such as 7-25%,
15-25%。
Further, which can be pesticide suspension concentrate（SC）.
Further, the present invention provides bactericidal composition dosage form be pesticide suspension concentrate when formula, each component weight
Percentage composition is：Fluoxastrobin 1-30%, difenoconazole 1-25%, hexaconazole 1-10%, wetting agent 1-3%, dispersant 1-10%, disappear
Infusion 0.1-0.5%, antifreezing agent 3-10%, thickener 0.5-5%, preservative 0.1-0.5%, surplus are water, and the sum of each ingredient is
100%。
Preferably, the weight percentage of each component is preferably in pesticide suspension concentrate：Fluoxastrobin 17.7%, phenyl ether methyl cyclic
Azoles 11.1%, hexaconazole 4.4%, wetting agent 1.5%, dispersant 5%, antifoaming agent 0.3%, antifreezing agent 5%, thickener 2.2%, preservative
0.2%, surplus is water, and the sum of each ingredient is 100%.
In above-mentioned pesticide suspension concentrate, the wetting agent is alkylbenzene sulfonate, aliphatic alcohol sulfate, alkylnaphthalene sulfonate
Condensation polymer, isopropyl naphthalene sulfonate, alkylphenol-polyethenoxy base ether, to methoxyl group fatty acyl amido benzene sulfonic acid sodium salt and dodecyl
Any one or more in sodium sulphate.
In above-mentioned pesticide suspension concentrate, the dispersant be naphthalenesulfonate formaldehyde condensation compound, alkylamide polyoxyethylene ether,
Polycarboxylate sodium, lignosulfonates, alkyl phenol polyoxyethylene ether, polyoxyethylene polyoxypropylene block copolymer, dodecyl
Polyoxyethylene ether phosphate and any one or more in double isopropyl naphthalene sulfonates.
In above-mentioned pesticide suspension concentrate, the antifoaming agent is organosiloxane, the fatty acid ester compounded object of higher alcohols, organosilicon
Ketone, C8-C10Fatty alcohol and C10-C20Any one in representative examples of saturated aliphatic carboxylic and its ester.
In above-mentioned pesticide suspension concentrate, the antifreezing agent is propylene glycol, ethylene glycol, diethylene glycol (DEG), glycerine, glycerine ether pair
Any one or more in glycol and methyl trimethylene diglycol.
In above-mentioned pesticide suspension concentrate, the thickener is carboxymethyl cellulose, xanthans, bentonite, white carbon and silicon
Any one or more in sour magnalium.
In above-mentioned pesticide suspension concentrate, the preservative is appointing in paraformaldehyde, Kathon CG, sodium benzoate and potassium sorbate
Meaning is a kind of.
Further, in above-mentioned pesticide suspension concentrate, the wetting agent is preferably isopropyl naphthalene sulfonate and dodecyl
Sodium sulphate in mass ratio 2:1 mixes；The dispersant is preferably naphthalenesulfonate formaldehyde condensation compound and polycarboxylate sodium by matter
Measure ratio 3:2 mix；The antifoaming agent is preferably organosilicon ketone；The antifreezing agent is preferably ethylene glycol and glycerine by matter
Measure ratio 1:1 mixes；The thickener is preferably xanthans and aluminium-magnesium silicate in mass ratio 1:10 mix；The anti-corrosion
Agent is preferably Kathon CG.
The preparation method of above-mentioned pesticide suspension concentrate includes the following steps：
（1）It is uniform through high speed shear after water, wetting agent, dispersant, antifoaming agent and preservative are mixed；
（2）Advance load weighted active ingredient Fluoxastrobin, difenoconazole and hexaconazole are added to step（1）It obtains
It is uniformly dispersed in mixed liquor and using dispersion impeller；
（3）By step（2）It is sanded in the mixture input horizontal sand mill of acquisition, frequent detectable substance is needed during sand milling
The particle size of material, it is 2-5 μm to be sanded to particle size；
（4）Load weighted thickener is added in antifreezing agent and is uniformly mixed, is added to above-mentioned steps（3）The mixing of acquisition
It in object, is uniformly mixed through high speed shear, the suspending agent product of the present composition is made.
The test of pesticide effectiveness shows that bactericidal composition of the present invention has good bactericidal effect, therefore the present invention to a variety of germs
Application of the bactericidal composition in preventing crop fungal disease is also protected.
Further, when by bactericidal composition for crop fungal disease protect when, the crop include wheat, corn,
Watermelon, rice and peanut etc..
Further, when preventing bactericidal composition for crop fungal disease, controlling object is fungus-caused
Disease caused by disease, especially basidiomycetes, Fungi Imperfecti, oomycetes and sac fungus.
They are compounded and bactericidal composition are made by the present invention using Fluoxastrobin, difenoconazole and hexaconazole as active ingredient,
The composition stability is good, can effectively play the advantage of three kinds of active ingredient, have apparent synergistic effect, to wheat, corn,
Nearly all fungi in watermelon, rice and peanut and other crops, especially causes basidiomycetes, Fungi Imperfecti, oomycetes and sac fungus
Control of plant disease effect protrude, the prevention spectrum of the composition is wider, while having protection and therapeutic effect.In addition, this three
The compounding of person can also reduce the dosage of active ingredient, delayed pathogen to generate resistance to it, be effectively protected day
Enemy has important economic implications, environment protection significance and ecological significance for the integrated control of harmful organism.
Specific implementation mode
The present invention is further explained in the light of specific embodiments.Illustrate merely to explain the present invention, it is not right
Its content is defined.Each ingredient used in the present invention can be bought in the market.
In following embodiments, unless otherwise instructed, each component content is weight percentage.
Embodiment 1
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, dispersant naphthalenesulfonate formaldehyde condensation compound 3%, poly- carboxylic
Acid sodium-salt 2%, antifoaming agent organosilicon ketone 0.3%, antifreeze glycol 2.5%, glycerine 2.5%, thickener xanthans 0.2%, silicon
Sour magnalium 2%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.2%, add water to supply 100%.
Preparation method is：
（1）It is passed through after mixing the water being pre-metered, wetting agent, dispersant, antifoaming agent and preservative according to above-mentioned formula
High speed shear is uniform；
（2）Advance load weighted active ingredient Fluoxastrobin, difenoconazole and hexaconazole are added to step（1）It obtains
It is uniformly dispersed in mixed liquor and using dispersion impeller；
（3）By step（2）It is sanded in the mixture input horizontal sand mill of acquisition, frequent detectable substance is needed during sand milling
The particle size of material, it is 2-5 μm to be sanded to particle size；
（4）Load weighted thickener is added in antifreezing agent and is uniformly mixed, is added to above-mentioned steps（3）The mixing of acquisition
It in object, is uniformly mixed through high speed shear, the aqueous suspension agent product of the present composition is made.
Embodiment 2
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（24.4% Fluoxastrobin, 4.4% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, dispersant naphthalenesulfonate formaldehyde condensation compound 3%, poly- carboxylic
Acid sodium-salt 2%, antifoaming agent organosilicon ketone 0.3%, antifreeze glycol 2.5%, glycerine 2.5%, thickener xanthans 0.2%, silicon
Sour magnalium 2%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.2%, add water to supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 3
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 13.3% difenoconazole, 2.2% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, dispersant naphthalenesulfonate formaldehyde condensation compound 3%, poly- carboxylic
Acid sodium-salt 2%, antifoaming agent organosilicon ketone 0.3%, antifreeze glycol 2.5%, glycerine 2.5%, thickener xanthans 0.2%, silicon
Sour magnalium 2%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.2%, add water to supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 4
Pesticidal aqueous suspension agent prescription is：Active ingredient 49.8%（26.6% Fluoxastrobin, 16.6% difenoconazole, 6.6% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, dispersant naphthalenesulfonate formaldehyde condensation compound 3%, poly- carboxylic
Acid sodium-salt 2%, antifoaming agent organosilicon ketone 0.3%, antifreeze glycol 2.5%, glycerine 2.5%, thickener xanthans 0.2%, silicon
Sour magnalium 2%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.2%, add water to supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 5
Pesticidal aqueous suspension agent prescription is：Active ingredient 9.9%（2.2% Fluoxastrobin, 5.5% difenoconazole, 2.2% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, dispersant naphthalenesulfonate formaldehyde condensation compound 3%, poly- carboxylic
Acid sodium-salt 2%, antifoaming agent organosilicon ketone 0.3%, antifreeze glycol 2.5%, glycerine 2.5%, thickener xanthans 0.2%, silicon
Sour magnalium 2%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.2%, add water to supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 6
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent alkylbenzene sulfonate 1%, alkylphenol-polyethenoxy base ether 2%, dispersant lignosulfonates 5%, alkyl phenol it is poly-
It is ethylene oxide ether 4%, antifoaming agent organosiloxane 0.1%, antifreezing agent propylene glycol 5%, diethylene glycol (DEG) 2.5%, thickener xanthans 0.2%, white
Carbon black 4.8%, preservative paraformaldehyde 0.4%, add water to supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 7
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent aliphatic alcohol sulfate 1%, dispersant alkylamide polyoxyethylene ether 10%, antifoaming agent higher alcohols it is fatty acid ester compounded
Object 0.5%, antifreezing agent glycerine ether diglycol 10%, thickener carboxymethyl cellulose 4%, preservative sodium benzoate 0.5%, add water to mend
Foot 100%.
The preparation method is the same as that of Example 1.
Embodiment 8
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent alkylnaphthalene sulfonate condensation polymer 1.8%, to methoxyl group fatty acyl amido benzene sulfonic acid sodium salt 0.3%, dispersant polyoxy second
Alkene polyoxypropylene block copolymers 0.5%, double isopropyl naphthalene sulfonates 0.5%, antifoaming agent C8-C10Fatty alcohol 0.25%, antifreezing agent
Methyl trimethylene diglycol 3%, thickener bentonite 0.5%, potassium sorbate preservative 0.25%, Jia Shui supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 9
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, alkylbenzene sulfonate 1%, dispersant dodecyl polyoxyethylene ether phosphate 2.4%,
Polycarboxylate sodium 4.7%, antifoaming agent C10-C20Representative examples of saturated aliphatic carboxylic and its ester 0.25%, antifreeze glycol 2.5%, methyl-prop
Support diglycol 3%, thickener xanthans 0.2%, carboxymethyl cellulose 2.6%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.1%, Jia Shui supply 100%.
The preparation method is the same as that of Example 1.
Embodiment 10
Pesticidal aqueous suspension agent prescription is：Active ingredient 33.2%（17.7% Fluoxastrobin, 11.1% difenoconazole, 4.4% own azoles
Alcohol）, wetting agent isopropyl naphthalene sulfonate 1%, lauryl sodium sulfate 0.5%, aliphatic alcohol sulfate 1.5%, dispersant naphthalene sulfonate
Formaldehyde condensation products 3%, polycarboxylate sodium 2%, double isopropyl naphthalene sulfonates 4.2%, antifoaming agent organosilicon ketone 0.25%, antifreezing agent second
Glycol 5%, thickener xanthans 0.2%, carboxymethyl cellulose 0.3%%, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.25%, Jia Shui supply 100%.
The preparation method is the same as that of Example 1.
Properties of product are tested
Pesticide suspension concentrate obtained by embodiment 1-10 is subjected to properties of product test, foaming characteristic reference standard：CIPAC
MT47.1, CIPAC MT47.2, suspensibility reference standard：CIPAC MT15, CIPAC MT168, heat storage stability is with reference to mark
It is accurate：GB/T 19136-2003, cold storage stability reference standard：GB/T 19137-2003, the results are shown in Table 1.
The product of embodiment 1-3 is other same other than effective ingredient proportioning is different, from data as can be seen that medicine
The variation of object active ingredient proportioning influences the performance of aqueous suspension agent little, products obtained therefrom good quality, and performance is stable, reliable.
There is difference in the product of embodiment 1,4,5, in effective ingredient content from data as can be seen that the C of too high levels product
Aqueous suspension rate reduces, and viscosity increases, and performance is affected.
It is equally good quality that embodiment 6-10, which uses not preferred auxiliary agent, products obtained therefrom, and properties of product are stable, reliable, full
The test request of the related performance of sufficient suspending agent, but C aqueous suspensions rate decreases compared with Example 1.
The test of pesticide effectiveness
Fluoxastrobin, difenoconazole and the hexaconazole compounding suspending agent of the present invention is outstanding compared with Fluoxastrobin, difenoconazole compounding
Floating agent has better bactericidal effect.Above-described embodiment is set forth below for rice sheath blight disease, watermelon anthrax, wheat leaf rust
With the test of pesticide effectiveness of the cercospora brown spot of peanut, while with 32.5% Fluoxastrobin difenoconazole suspending agent（A meter Miao is received, Syngenta）,
10% difenoconazole water dispersible granule（Generation is high, Syngenta）With 25% Fluoxastrobin suspending agent（Amici reaches, Syngenta）As right
According to the advantages of illustrating the present composition.
The rice sheath blight disease test of pesticide effectiveness：
The test arrangement the Jining City Jiaxiang County towns Liang Baosi face south village carry out, experiment use RANDOMIZED BLOCK DESIGN, cell
Area 32m2, in the booting latter stage of rice and each dispenser of full heading time 1 time, spraying equipment is Singapore's profit agriculture 16L knapsack sprayings
Device, and it is fine for 24 hours before and after dispenser, without rainfall.It is each embodiment medicament and comparison medicament to apply drug, is arranged simultaneously
Clear water blank control.Disease index radix is investigated before first time dispenser, 30d carries out the 2nd investigation after second, and investigation is adopted
With five point sampling, every is investigated 30 plants, according to following standard recording incidence.
0 grade：Complete stool is disease-free；
1 grade：Quaterfoil and its morbidity of following leaf sheath blade；
3 grades：Third blade and its morbidity of following leaf sheath blade；
5 grades：Second blade and its morbidity of following leaf sheath blade；
7 grades：Sword-like leave blade and its morbidity of following leaf sheath blade；
9 grades：Complete stool falls ill, withered ahead of time.
Disease index computational methods：
Each medicament see the table below 2 to the control effect of rice sheath blight disease.
Watermelon anthrax is tested：
The test arrangement carries out in Changyue County of Weifang City towns Yao Gou villages little Lou, and experiment uses RANDOMIZED BLOCK DESIGN, cell face
Product 25m2, in watermelon growing mid-term, watermelon anthrax early stage carries out dispenser.It is each embodiment medicament and control to apply drug
Medicament, while clear water blank control is set.State of an illness radix is investigated before dispenser, 10d carries out the 2nd Disease investigation after dispenser, and remembers
Corresponding disease index is recorded, spraying equipment is Singapore's profit agriculture 16L knapsack sprayers, and fine for 24 hours before and after dispenser,
Without rainfall.Each cell random searching 15 is climing when investigation, per climing from the 5th, top leaf 10 leaves of number down, amounts to 150
Leaf, records the corresponding sick number of sheets and sick series, severity Scaling method are as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire blade area；
3 grades：Lesion area accounts for the 6% ~ 10% of entire blade area；
5 grades：Lesion area accounts for the 11% ~ 25% of entire blade area；
7 grades：Lesion area accounts for the 26% ~ 50% of entire blade area；
9 grades：Lesion area accounts for 50% or more of entire blade area.
Disease index and the same rice sheath blight disease of preventive effect computational methods, experimental result is shown in the following table 3.
Wheat leaf embroiders disease experiment：
The test arrangement carries out in the hollow street river bend village in Shandong Weifang strand economic and technological development zone, experiment using with
Machine block design, plot area 666.7m2, started medication at the initial stage that disease occurs, spraying equipment is carried on the back for Singapore profit agriculture 16L
Negative formula sprayer, and it is fine for 24 hours before and after dispenser, without rainfall.Apply drug be each embodiment medicament and comparison medicament,
Clear water blank control is set simultaneously.The radix of disease is investigated before medication, interval 7d sprays a medicine, 14d tune after spraying at second
The state of an illness is looked into as a result, investigation uses 5 point samplings, investigate 20 plants, 3 leaves in every plant of investigation top, with scab face on every leaf at every
Product accounts for the percentage classification of entire leaf area, and grade scale is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire blade area；
3 grades：Lesion area accounts for the 6% ~ 10% of entire blade area；
5 grades：Lesion area accounts for the 11% ~ 25% of entire blade area；
7 grades：Lesion area accounts for the 26% ~ 50% of entire blade area；
9 grades：Lesion area accounts for 50% or more of entire blade area.
Disease index and the same rice sheath blight disease of preventive effect computational methods, experimental result is shown in the following table 4.
The cercospora brown spot of peanut is tested：
The test arrangement carries out in the hollow street river bend village in Shandong Weifang strand economic and technological development zone, experiment using with
Machine block design, plot area 333.3m2, started medication at the initial stage that disease occurs, spraying equipment is carried on the back for Singapore profit agriculture 16L
Negative formula sprayer, and it is fine for 24 hours before and after dispenser, without rainfall.Apply drug be each embodiment medicament and comparison medicament,
Clear water blank control is set simultaneously.The radix of disease is investigated before medication, interval 10d sprays a medicine, 10d tune after spraying at second
The state of an illness is looked into as a result, investigation uses 5 point samplings, investigate 10 plants, every plant of investigation 5 blades of stem, with scab on every leaf at every
Area accounts for the percentage classification of entire leaf area, and grade scale is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire blade area；
3 grades：Lesion area accounts for the 6% ~ 25% of entire blade area；
5 grades：Lesion area accounts for the 26% ~ 50% of entire blade area；
7 grades：Lesion area accounts for the 51% ~ 75% of entire blade area；
9 grades：Lesion area accounts for 76% or more of entire blade area.
Disease index and the same rice sheath blight disease of preventive effect computational methods, experimental result is shown in the following table 5.
It is found by above-mentioned experiment, using the bactericidal composition of the present invention for rice sheath blight disease, watermelon anthrax, wheat
Leaf rust and cercospora brown spot of peanut control effect protrude, and preventive effect will be apparently higher than contrast agents, and safe for plant growth,
Have no adverse effects generation.
Claims (7)
1. a kind of bactericidal composition, it is characterized in that：Active ingredient is Fluoxastrobin, difenoconazole and hexaconazole, and dosage form is pesticide
Aqueous suspension agent, each component weight percentage are：Fluoxastrobin 1-30%, difenoconazole 1-25%, hexaconazole 1-10%, wetting agent
1-3%, dispersant 1-10%, antifoaming agent 0.1-0.5%, antifreezing agent 3-10%, thickener 0.5-5%, preservative 0.1-0.5%, surplus
For water；
The wetting agent is isopropyl naphthalene sulfonate and lauryl sodium sulfate in mass ratio 2:1 mixes；The dispersant
For naphthalenesulfonate formaldehyde condensation compound and polycarboxylate sodium in mass ratio 3:2 mix；The antifoaming agent is organosilicon ketone；Institute
It is ethylene glycol and glycerine in mass ratio 1 to state antifreezing agent:1 mixes；The thickener is that xanthans and aluminium-magnesium silicate press matter
Measure ratio 1:10 mix；The preservative is Kathon CG.
2. bactericidal composition according to claim 1, it is characterized in that：The quality of Fluoxastrobin, difenoconazole and hexaconazole
Than for 1-8:1-6:1.
3. bactericidal composition according to claim 2, it is characterized in that：The quality of Fluoxastrobin, difenoconazole and hexaconazole
Than for 3.93-4.1:2.47-2.55:1.
4. bactericidal composition according to any one of claim 1-3, it is characterized in that：Each component weight percentage is：
Fluoxastrobin 1-30%, difenoconazole 1-25%, hexaconazole 1-10%, wetting agent 1.5%, dispersant 5%, antifoaming agent 0.3%, antifreezing agent
5%, thickener 2.2%, preservative 0.2%, surplus are water.
5. bactericidal composition according to claim 4, it is characterized in that：Each component weight percentage is：Fluoxastrobin
17.7%, difenoconazole 11.1%, hexaconazole 4.4%, wetting agent 1.5%, dispersant 5%, antifoaming agent 0.3%, antifreezing agent 5%, thickening
Agent 2.2%, preservative 0.2%, surplus are water.
6. bactericidal composition according to claim 1, it is characterized in that：The content of Fluoxastrobin, difenoconazole and hexaconazole
The sum of be 9-50wt%.
7. application of the bactericidal composition in preventing crop fungal disease described in any one of claim 1-6, it is characterized in that：
The crop includes rice, wheat, corn, watermelon or peanut.
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|---|---|---|---|---|
| CN101911940A (en) * | 2010-09-08 | 2010-12-15 | 吴元林 | Germicide compounded from azoxystrobin, difenoconazole and cyproconazole and preparation method thereof |
| CN101584323B (en) * | 2009-04-15 | 2012-06-27 | 陕西蒲城县美邦农药有限责任公司 | Azoxystrobin and hexaconazole-containing antiseptic composition |
| CN102669111A (en) * | 2012-05-24 | 2012-09-19 | 利民化工股份有限公司 | Suspending agent formulated by difenoconazole and azoxystrobin and preparation method thereof |
| CN102057912B (en) * | 2010-12-19 | 2013-04-17 | 惠州市银农科技有限公司 | Water suspending agent mixed by difenoconazole and azoxystrobin and preparation method thereof |
| WO2015062358A1 (en) * | 2013-10-30 | 2015-05-07 | Rotam Agrochem International Company Limited | Method of increasing yield by treating with fungicidal compositions |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584323B (en) * | 2009-04-15 | 2012-06-27 | 陕西蒲城县美邦农药有限责任公司 | Azoxystrobin and hexaconazole-containing antiseptic composition |
| CN101911940A (en) * | 2010-09-08 | 2010-12-15 | 吴元林 | Germicide compounded from azoxystrobin, difenoconazole and cyproconazole and preparation method thereof |
| CN102057912B (en) * | 2010-12-19 | 2013-04-17 | 惠州市银农科技有限公司 | Water suspending agent mixed by difenoconazole and azoxystrobin and preparation method thereof |
| CN102669111A (en) * | 2012-05-24 | 2012-09-19 | 利民化工股份有限公司 | Suspending agent formulated by difenoconazole and azoxystrobin and preparation method thereof |
| WO2015062358A1 (en) * | 2013-10-30 | 2015-05-07 | Rotam Agrochem International Company Limited | Method of increasing yield by treating with fungicidal compositions |
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