CN105687040B - A kind of multi-functional lotion and preparation method thereof of zymolyte containing seaweed and collagen - Google Patents

Abstract

The invention discloses a multifunctional emulsion containing seaweed hydrolyzate and collagen, which comprises: 1,3-butanediol, glycerol, polysorbate-20, panthenol, cetyl alcohol, stearyl alcohol Alcohol, Tocopherol, Allantoin, Hyaluronic Acid, Disodium EDTA, Sweet Almond Oil, Squalane, Octyldodecanol, Lemon Essential Oil, Seaweed Enzyme Hydrolyzate, Fish Scale Collagen, Triethanolamine ; The present invention also discloses the preparation method of the above-mentioned multifunctional emulsion. The multifunctional emulsion of the present invention uses the enzymatic hydrolyzate of large seaweed and fish scale collagen as the main active ingredients, and adds active ingredients such as hyaluronic acid, tocopherol, squalane and allantoin, and mixes and homogenizes with the cosmetic base to form It has the advantages of safety, mildness, whitening, moisturizing, anti-wrinkle, anti-aging, and non-irritating. It will not damage the skin, but also has the effects of whitening, anti-wrinkle, and anti-aging while protecting and moisturizing.

Description

A kind of multifunctional emulsion containing seaweed hydrolyzate and collagen and preparation method thereof

technical field

The invention relates to the technical field of cosmetics, in particular to a multifunctional emulsion containing seaweed hydrolyzate and collagen and a preparation method thereof.

Background technique

With the development of society, the advancement of medicine and the improvement of quality of life, people begin to pay attention to the maintenance of skin. Due to the increasing air pollution and the increasing pressure of life in modern society, more and more people's skin is attacked by external environmental pollution and internal free radicals, and a series of symptoms such as dullness, dryness, sensitivity, and aging appear. As people pay more attention to skin care issues, lotion is an essential part of the daily skin care program. Emulsion is a liquid cream cosmetic with good moisturizing and emollient effect. Currently, the emulsion on the market often adds too many chemicals and preservatives. Although it can achieve the purpose of improving the skin in a short time, it will cause skin dependence or Strong irritation to skin. Therefore, a healthy and non-irritating emulsion added with natural marine bioactive substances will be loved by consumers.

Marine bioactive extracts have been valued by researchers and favored by the beauty industry because of their excellent biocompatibility, definite moisturizing and water-retaining effect and clear biological activity. Marine bioactive substances such as collagen, phenols, and oligosaccharides have been successfully developed into various cosmetics, but multifunctional emulsions containing seaweed hydrolyzate and collagen are still blank. Collagen is a structural protein that exists in the intercellular substance. It is widely distributed in animal connective tissue. Excellent biochemical compatibility and many other advantages. At present, although there are invention patents that use fish skin and other marine biological materials instead of pig and cowhide as new raw materials for extracting collagen, which has higher biological safety and excellent biological characteristics, but fish skin has a strong fishy smell, and the deodorization technology Time-consuming and labor-intensive, fish scales have become a new material for extracting collagen.

At present, although there are invention patents disclosing the preparation method of seaweed extract and collagen, and pointing out that it can be used in cosmetics, there is no enzymatic extraction of more comprehensive and nutritious seaweed extract, for example: Chinese patent application number 201310257256.6 Disclosed is a seaweed extract functional emulsion, the seaweed extract in the emulsion does not use enzymatic method to extract more active ingredients. There are also invention patents that use marine biological materials such as fish skin instead of pig and cowhide as new raw materials for extracting collagen, but fish skin has a strong fishy smell, and the removal technology is time-consuming and laborious. Therefore, this patent uses fish scales as the material for extracting collagen. The Chinese patent application number 201010553485.9 discloses a marine fish skin collagen moisturizing anti-aging cosmetic, which uses fish skin as the collagen extraction material, but the fish skin has a strong fishy smell and the extraction cost is relatively high.

Therefore, in the field of cosmetic technology, it is urgent to provide a multi-functional product containing seaweed enzymatic hydrolyzate and collagen that is safe, mild and efficient, not only does not damage the skin, but also achieves whitening, anti-wrinkle and anti-aging effects while protecting and moisturizing. lotion.

Contents of the invention

In order to solve the above problems, the present invention provides a multifunctional emulsion containing seaweed enzymatic hydrolyzate and collagen that is safe, mild and efficient, not only does not damage the skin, but also achieves whitening, anti-wrinkle and anti-aging effects while protecting and moisturizing .

The technical scheme adopted in the present invention is: a multifunctional emulsion containing seaweed hydrolyzate and collagen, including the following components: 1,3-butanediol, glycerol, polysorbate-20, panthenol, Cetyl Alcohol, Stearyl Alcohol, Tocopherol, Allantoin, Hyaluronic Acid, Disodium EDTA, Sweet Almond Oil, Squalane, Octyldodecanol, Lemon Essential Oil, Seaweed Enzyme Hydrolyzate, Fish scale collagen, triethanolamine, deionized water;

Further, each component by weight percentage: 1,3-butanediol 1%-10%, glycerol 1%-10%, polysorbate-20 1%-6%, panthenol 0.5%- 5%, cetyl alcohol 0.5%-4%, stearyl alcohol 0.5%-4%, tocopherol 0.1%-4%, allantoin 0.05%-4%, hyaluronic acid 0.05%-6%, ethylenediamine Disodium tetraacetate 0.05%-2%, sweet almond oil 1%-10%, squalane 1%-8%, octyldodecanol 0.5%-4%, lemon essential oil 0.05%-2%, seaweed enzyme Hydrolyzate 0.01%-10%, fish scale collagen 0.01%-10%, the balance is triethanolamine and deionized water;

Further, each component by weight percentage: 1,3-butanediol 5%, glycerol 5%, polysorbate-204%, panthenol 1%, cetyl alcohol 1%, stearyl alcohol 1% %, tocopherol 0.5%, allantoin 0.2%, hyaluronic acid 0.1%, edetate disodium 0.1%, sweet almond oil 3%, squalane 3%, octyldodecanol 2%, Lemon essential oil 0.1%, seaweed hydrolyzate 2%, fish scale collagen 0.5%, the balance is triethanolamine and deionized water;

Further, each component by weight percentage: 1,3-butanediol 7%, glycerol 8%, polysorbate-204%, panthenol 2%, cetyl alcohol 1.5%, stearyl alcohol 1.5% %, tocopherol 1%, allantoin 0.5%, hyaluronic acid 0.3%, edetate disodium 0.1%, sweet almond oil 5%, squalane 2%, octyldodecanol 4%, Lemon essential oil 0.05%, seaweed hydrolyzate 1%, fish scale collagen 1%, the balance is triethanolamine and deionized water;

Further, each component is calculated by weight percentage; 1,3-butanediol 3%, glycerol 10%, polysorbate-206%, panthenol 5%, cetyl alcohol 0.5%, stearyl alcohol 0.5% %, tocopherol 4%, allantoin 1%, hyaluronic acid 3%, edetate disodium 0.5%, sweet almond oil 5%, squalane 5%, octyldodecanol 4%, 0.5% lemon essential oil, 0.5% seaweed hydrolyzate, 0.5% fish scale collagen, and the balance is triethanolamine and deionized water.

The present invention also discloses the preparation method of the above-mentioned multifunctional emulsion containing seaweed hydrolyzate and collagen, and the specific steps include:

1) Preparation of seaweed enzymatic hydrolyzate: rinse the seaweed, dry it, and crush it to obtain algal powder. According to the ratio of 1g of algae powder plus 500-1000U/g of enzyme to 100mL of water, mix the algae powder, enzyme and water Evenly, keep the temperature at 30-60°C, extract under shaking conditions for 6-24 hours, centrifuge under the condition of 4000-8000r/min for 15min, spin evaporate after suction filtration, and obtain seaweed hydrolyzate after freeze-drying;

2) Preparation of fish scale collagen: after washing fresh fish scales with water and removing impurities, soak fish scales with 0.2mol/L EDTA solution at a w/v ratio of 1:30 for decalcification, and then mix with 0.1mol/L Sodium hydroxide solution according to w/v is 1:8 solid-liquid ratio, soak 6h to remove non-collagen protein, add 2000U/g pepsin, and 2-10% citric acid solution through decalcification and non-collagen protein fish scale According to the solid-liquid ratio of w/v 1:18, soak for 24-48h to extract; filter through a 300-mesh filter cloth to obtain collagen extract, add sodium chloride to the extract until its concentration reaches 0.9mol/L, and salt out 24h, then centrifuge to obtain the collagen precipitate, place the precipitate in a dialysis bag with a molecular weight cut-off of 10kD and dialyze for 24h, freeze-dry for use;

3) Preparation of multifunctional emulsion: 1,3-butanediol, glycerol, polysorbate-20, panthenol, cetyl alcohol, stearyl alcohol, tocopherol, allantoin, hyaluronic acid 1. Mix disodium ethylenediamine tetraacetate according to weight percentage, add the remaining amount of deionized water obtained after calculating according to the weight percentage of each material, and heat to 70-75 ° C under stirring conditions to completely dissolve it to obtain a water phase;

In another container, sweet almond oil, squalane, and octyldodecanol are added sequentially by weight percentage and heated to 70-75°C under stirring conditions to melt it into a liquid state to obtain an oil phase;

Add the oil phase to the water phase, cool down to 40-50°C, add lemon essential oil, seaweed enzymatic hydrolyzate and fish scale collagen, and stir at high speed with a mixer;

Use triethanolamine to adjust the pH of the emulsion to 5.0-6.0, homogenize with a homogenizer for 5-60 minutes, and cool to room temperature;

The emulsion is aged at room temperature for 1-3 days, and the product multifunctional emulsion is obtained after filling;

Further, the seaweed described in step 1) is one or a combination of several seaweeds in brown algae, red algae and green algae;

Further, the enzyme described in step 1) is one or a combination of alkaline protease, cellulase, pentosan complex enzyme, and cellulose complex enzyme.

Beneficial effects of the present invention:

Compared with cosmetic emulsions containing a large amount of chemical agents and preservatives on the market, the multifunctional emulsion containing seaweed hydrolyzate and collagen of the present invention solves the problem of using chemical preparations by adding active substances containing seaweed hydrolyzate and collagen. and preservatives are likely to cause irritation. By adding polyphenols and oligosaccharides in the enzymatic hydrolyzate, fish scale collagen, etc., the nutrients in the emulsion are more comprehensive and diverse, and will not irritate the skin. It will cause problems such as dependence for consumers. It is safe, mild and efficient. Not only will it not damage the skin, but it can also achieve whitening, anti-wrinkle and anti-aging effects while protecting and moisturizing.

The present invention selects pure natural large seaweed and fish scales as main raw materials, adopts an enzymatic extraction process to extract various bioactive substances in seaweed, and extracts collagen from fish scales, which has less fishy smell and low extraction cost. These natural active substances can It is quickly absorbed by the skin, does not bring burden to the skin, is safe, mild, and does not cause skin allergies, so that the multifunctional emulsion of the present invention has the effects of whitening, moisturizing, anti-wrinkle, anti-aging and repairing damaged skin. Moreover, the seaweed enzymatic hydrolyzate contains natural antibacterial agents with good antibacterial effect, no need to add chemical preservatives, non-toxic and non-irritating, suitable for people of different genders, ages and skin types, cost-effective, green and environmentally friendly, and its preparation process is simple and easy OK, low production cost, suitable for industrialized production.

Detailed ways

Example 1:

1, composition and weight content thereof of multifunctional cosmetic emulsion of the present invention are:

Phase A: 1,3-butanediol (5%), glycerol (5%), polysorbate-20 (4%), panthenol (1%), cetyl alcohol (1%), Octanol (1%), Tocopherol (0.5%), Allantoin (0.2%), Hyaluronic Acid (0.1%), Disodium EDTA (0.1%);

Phase B: sweet almond oil (3%), squalane (3%), octyldodecanol (2%), lemon essential oil (0.1%);

Phase C: seaweed hydrolyzate (2%), fish scale collagen (0.5%);

Phase D: Adjust pH to 5.5 with triethanolamine.

2. Process:

1) Preparation of the seaweed enzymatic hydrolyzate: clean the hijiki, dry it, and pulverize it to obtain algal powder, mix 1 g of algae powder with 500 U/g of alkaline protease and 100 mL of water evenly, and keep the temperature at 45 ℃, reacted under shaking conditions for 12 hours, centrifuged at 4000rpm for 15 minutes, filtered the supernatant, rotary evaporated after suction filtration, and freeze-dried to obtain hijiki enzymatic hydrolyzate;

2) Preparation of the collagen protein: after fresh cod scales are washed with water and impurities removed, the scales are soaked in 0.2mol/LEDTA solution for 24 hours at a material-to-liquid ratio of 1:30 (w/v) for decalcification; then mixed with 0.1mol/LEDTA solution L sodium hydroxide solution according to 1:8 (w/v) solid-liquid ratio, soak 6h to remove non-collagen protein; Add 2000U/g pepsin to the fish scales through decalcification and non-collagen protein, and 6% citric acid solution according to 1:18 (w/v) ratio of material to liquid, soak for 24 hours to extract; filter through 300 mesh filter cloth to obtain collagen extract, add sodium chloride to the extract until its concentration reaches 0.9mol/L, salt out for 24 hours, Then centrifuge to obtain the collagen precipitate; place the precipitate in a dialysis bag with a molecular weight cut-off of 10kD and dialyze for 24 hours, and freeze-dry the extracted fish scale collagen;

3) Preparation of multifunctional emulsion: heat phase A and phase B to 75°C respectively, add phase B into phase A under stirring condition, homogenize for 5 minutes; Add it to the mixture of phases A and B; adjust the pH of the system to 5.5 with triethanolamine, and age at room temperature for 3 days to prepare a multifunctional emulsion containing seaweed hydrolyzate and collagen.

Example 2:

1, composition and weight content thereof of multifunctional cosmetic emulsion of the present invention are:

Phase A: 1,3-butanediol (7%), glycerol (8%), polysorbate-20 (4%), panthenol (2%), cetyl alcohol (1.5%), Octanol (1.5%), Tocopherol (1%), Allantoin (0.5%), Hyaluronic Acid (0.3%), Disodium EDTA (0.1%);

Phase B: sweet almond oil (5%), squalane (2%), octyldodecanol (4%), lemon essential oil (0.05%);

Phase C: seaweed hydrolyzate (1%), fish scale collagen (1%);

Phase D: Adjust pH to 5.0 with triethanolamine.

2. Process:

1) Preparation of the seaweed enzymatic hydrolyzate: clean the algae, dry them, and crush them to obtain algal powder, mix 1 g of algae powder with 800 U/g cellulase and 100 mL of water evenly, and keep the temperature at 50°C , reacted under shaking conditions for 6h, centrifuged at 6000rpm for 15min, filtered the supernatant with suction, evaporated on a rotary basis after suction filtration, and freeze-dried to obtain the enzymatic hydrolyzate of algae japonica;

2) Preparation of the collagen: fresh grass carp scales were washed with water and impurities removed, then soaked in 0.2mol/LEDTA solution for 24 hours to decalcify the scales with 0.2mol/LEDTA solution at a ratio of 1:30 (w/v), and then mixed with 0.1mol/LEDTA solution. L sodium hydroxide solution according to 1:8 (w/v) solid-liquid ratio, soak 6h to remove non-collagen protein, add 2000U/g pepsin through decalcification and non-collagen protein fish scale, and 4% citric acid solution according to 1:18 (w/v) ratio of material to liquid, soak for 32 hours to extract, filter through 300 mesh filter cloth to obtain collagen extract, add sodium chloride to the extract until its concentration reaches 0.9mol/L, salt out for 24 hours, Then centrifuge to obtain the collagen precipitate, place the precipitate in a dialysis bag with a molecular weight cut-off of 10kD and dialyze for 24 hours, and freeze-dry the extracted fish scale collagen;

3) Preparation of multifunctional emulsion: heat phase A and phase B to 75°C respectively, add phase B into phase A under stirring condition, homogenize for 20 minutes; stir and cool to below 45°C, and mix the components of phase C Add it to the mixture of phases A and B; adjust the pH of the system to 5.0 with triethanolamine, and age at room temperature for 3 days to prepare a multifunctional emulsion containing seaweed hydrolyzate and collagen.

Example 3:

1, composition and weight content thereof of multifunctional cosmetic emulsion of the present invention are:

Phase A: 1,3-butanediol (3%), glycerol (10%), polysorbate-20 (6%), panthenol (5%), cetyl alcohol (0.5%), Octanol (0.5%), Tocopherol (4%), Allantoin (1%), Hyaluronic Acid (3%), Disodium EDTA (0.5%);

Phase B: Sweet Almond Oil (5%), Squalane (5%), Octyldodecanol (4%), Lemon Essential Oil (0.5%);

Phase C: seaweed hydrolyzate (0.5%), fish scale collagen (0.5%);

Phase D: Adjust pH to 6.0 with triethanolamine.

2. Process:

1) Preparation of the seaweed enzymatic hydrolyzate: clean the algal algae, dry and pulverize to obtain algal powder, mix 1 g of algae powder with 1000 U/g of enzyme and 100 mL of water evenly, keep the temperature at 40°C, React for 6 hours under shaking conditions, centrifuge at 8000rpm for 15 minutes, filter the supernatant, rotate evaporate after suction filtration, and freeze-dry to prepare the enzymatically hydrolyzed active substance of algae multipriste;

2) Preparation of the collagen: fresh silver carp scales were washed with ice-pure water to remove impurities, then soaked in 0.2mol/LEDTA solution for 24 hours to decalcify the fish scales at a ratio of 1:30 (w/v) to liquid, and then mixed with 0.1mol/L sodium hydroxide solution according to 1:8 (w/v) ratio of material to liquid, soak for 6h to remove non-collagen, add 2000U/g pepsin to decalcified and non-collagen fish scales, and 2% lemon According to the ratio of material to liquid of 1:18 (w/v), the acid solution was soaked for 48 hours to extract; the collagen extract was obtained by filtering through a 300-mesh filter cloth, and sodium chloride was added to the extract until its concentration reached 0.9mol/L. Analyze for 24 hours, then centrifuge to obtain the collagen precipitate, place the precipitate in a dialysis bag with a molecular weight cut-off of 10kD and dialyze for 24 hours, freeze-dry to obtain the extracted fish scale collagen;

3) Preparation of multifunctional emulsion: heat phase A and phase B to 75°C respectively, add phase B into phase A under stirring condition, homogenize for 60 minutes, stir and cool to below 45°C, and mix the components of phase C Add it to the mixture of phases A and B in sequence; adjust the pH of the system to 6.0 with triethanolamine, and age at room temperature for 3 days to prepare a multifunctional emulsion containing seaweed hydrolyzate and collagen.

Example 4:

1. Activity evaluation of seaweed hydrolyzate:

Table 1

2. The inhibitory effect of emulsion on tyrosinase:

Table 2

sample Tyrosinase inhibition rate Example 1 20.44% Example 2 22.31% Example 3 15.04%

3. Antioxidant ability of emulsion:

table 3

sample DPPH clearance Hydroxyl radical scavenging rate superoxide anion scavenging rate Example 1 75.23% 40.12% 60.11% Example 2 78.89% 41.21% 61.54% Example 3 70.22% 38.03% 57.79%

4. Moisture absorption and moisturizing properties of emulsion:

Table 4

sample Moisture rate Example 1 90.13% Example 2 92.01% Example 3 88.36%

5. Detection of sensory and physical and chemical properties of emulsion:

table 5

6. The above test results show that the emulsion of the present invention has good tyrosinase inhibitory effect and the ability to scavenge DPPH, hydroxyl radicals and superoxide anions and moisture absorption and moisturizing properties after adding seaweed hydrolyzate. Added in the emulsion, the functional effect of the emulsion is further enhanced, not only can effectively inhibit tyrosinase, scavenge free radicals, but also comprehensively repair and nourish the skin, improve the self-protection ability of the skin, and make the emulsion of the present invention have Moisturizing, nourishing, whitening, anti-inflammatory, repairing and other multiple functions, it is tested for sensory and physical and chemical properties, and found to be in line with national standards, it is a qualified product.

The above-mentioned embodiments are only to illustrate the technical concept and characteristics of the present invention, and its purpose is to enable those of ordinary skill in the art to understand the content of the present invention and implement it accordingly, and cannot limit the protection scope of the present invention. All equivalent changes or modifications made according to the essence of the present invention shall fall within the protection scope of the present invention.

Claims (6)

1. the multi-functional lotion of a kind of zymolyte containing seaweed and collagen, which is characterized in that by each of following weight percent Group is grouped as：1,3-BDO 1%-10%, glycerine 1%-10%, -20 1%-6% of polysorbate, panthenol 0.5%- 5%, hexadecanol 0.5%-4%, octadecyl alcolol 0.5%-4%, tocopherol 0.1%-4%, allantoin 0.05%-4%, hyaluronic acid 0.05%-6%, disodium ethylene diamine tetraacetate 0.05%-2%, Sweet Almond Oil 1%-10%, saualane 1%-8%, octyl 12 Alkanol 0.5%-4%, lemon 0.05%-2%, seaweed zymolyte 0.01%-10%, fish scale collagen 0.01%- 10%, surplus is triethanolamine and deionized water；The preparation method of above-mentioned multi-functional lotion includes the following steps：

1) preparation of seaweed zymolyte：After seaweed is rinsed well, drying crushes to obtain algae powder, adds 500- according to 1g algae powder Algae powder, enzyme are uniformly mixed by the ratio of the enzyme of 1000U/g and the water of 100mL with water, maintain the temperature at 30-60 DEG C, oscillating condition Lower extraction 6-24 hours centrifuges 15min under the conditions of 4000-8000r/min, is rotated after suction filtration, and seaweed enzymolysis is obtained after freeze-drying Object；

2) preparation of fish scale collagen：Fresh fish scale washes with water, clean after, fish scale and 0.2mol/L EDTA solution are pressed The solid-liquid ratio for being 1: 30 according to w/v impregnates decalcification for 24 hours, then the solid-liquid ratio for being 1: 8 according to w/v with 0.1mol/L sodium hydroxide solutions, It impregnates 6h and removes non-collagen, by through decalcification and except the fish scale of non-collagen adds 2000U/g pepsins, with 2-10%'s The solid-liquid ratio that citric acid solution is 1: 18 according to w/v impregnates 24-48h extractions；Collagen is obtained through 300 mesh filter-cloth filterings to carry Liquid is taken, sodium chloride to its concentration is added into extracting solution and reaches 0.9mol/L, is saltoutd for 24 hours, is then centrifuged for obtaining collagen deposit Object puts the precipitate in the bag filter that trapped molecular weight is 10kD and dialyses for 24 hours, and freeze-drying is spare；

3) preparation of multi-functional lotion：Successively by 1,3-BDO, glycerine, polysorbate -20, panthenol, hexadecanol, 18 Alcohol, tocopherol, allantoin, hyaluronic acid, disodium ethylene diamine tetraacetate mix by weight percentage, are added and press each weight of material hundred Divide in the deionized water than calculating the surplus obtained later, 70-75 DEG C is heated under stirring condition, is allowed to be completely dissolved, is obtained Aqueous-phase material；

It sequentially adds in another container under Sweet Almond Oil by weight percentage, saualane, octyldodecanol stirring condition It is heated to 70-75 DEG C, it is made to be fused into liquid, obtains oil phase thing；

Oil phase thing is added in aqueous-phase material, lemon, the seaweed enzymolysis being added after 40-50 DEG C by weight percentage are cooled to Object and fish scale collagen, with blender high-speed stirred；

Lotion pH to 5.0-6.0 is adjusted with triethanolamine, homogenizer homogeneous 5-60min is cooled to room temperature；

Lotion is aged 1-3 days at room temperature, and the multi-functional lotion of product is obtained after filling.

2. multi-functional lotion as described in claim 1, which is characterized in that be grouped as by each group of following weight percent：1, 3- butanediols 5%, glycerine 5%, polysorbate -20 4%, panthenol 1%, hexadecanol 1%, octadecyl alcolol 1%, tocopherol 0.5%, allantoin 0.2%, hyaluronic acid 0.1%, disodium ethylene diamine tetraacetate 0.1%, Sweet Almond Oil 3%, saualane 3%, Octyldodecanol 2%, lemon 0.1%, seaweed zymolyte 2%, fish scale collagen 0.5%, surplus are triethanolamine And deionized water.

3. multi-functional lotion as described in claim 1, which is characterized in that be grouped as by each group of following weight percent：1, 3- butanediols 7%, glycerine 8%, polysorbate -20 4%, panthenol 2%, hexadecanol 1.5%, octadecyl alcolol 1.5%, fertility Phenol 1%, allantoin 0.5%, hyaluronic acid 0.3%, disodium ethylene diamine tetraacetate 0.1%, Sweet Almond Oil 5%, saualane 2%, Octyldodecanol 4%, lemon 0.05%, seaweed zymolyte 1%, fish scale collagen 1%, surplus be triethanolamine and Deionized water.

4. multi-functional lotion as described in claim 1, which is characterized in that be grouped as by each group of following weight percent：1, 3- butanediols 3%, glycerine 10%, polysorbate -20 6%, panthenol 5%, hexadecanol 0.5%, octadecyl alcolol 0.5%, fertility Phenol 4%, allantoin 1%, hyaluronic acid 3%, disodium ethylene diamine tetraacetate 0.5%, Sweet Almond Oil 5%, saualane 5%, octyl Dodecanol 4%, lemon 0.5%, seaweed zymolyte 0.5%, fish scale collagen 0.5%, surplus be triethanolamine and Deionized water.

5. multi-functional lotion as described in claim 1, which is characterized in that the seaweed described in step 1) is brown alga, red algae, green The combination of one or more of algae seaweed.

6. multi-functional lotion as described in claim 1, which is characterized in that the enzyme described in step 1) is alkali protease, fibre One or more of combinations of dimension plain enzyme, pentosan complex enzyme, cellulose complex enzyme.