CN105561000B - A kind of emergency department's nursing quick-acting haemostatic powder patch - Google Patents
A kind of emergency department's nursing quick-acting haemostatic powder patch Download PDFInfo
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The present invention relates to a kind of emergency department's nursing quick-acting haemostatic powder patches, it is made of back sheet, load medicine adhesive layer and adherent layer, it carries medicine adhesive layer to be made of the raw material of following parts by weight: 0.01-0.5 parts of vitamin K1,0.01-0.5 parts of para-amino-methyl-benzoic acid, 0.01-0.5 parts of adrenobazonum, 10-25 parts of carboxymethyl chitosan, 10-20 parts of Honegsukle flower P.E, 10-20 parts of cogongrass rhizome extractive, 10-20 parts of Pollen Tyjphae extract, 10-30 parts of hydroxypropyl methyl cellulose, 10-20 parts of pressure sensitive adhesive, 5-15 parts of glycerol, 20-50 parts of deionized water.Patch produced by the present invention not only has bacteriostasis, moreover it is possible to achieve the effect that quick-acting haemostatic powder, promote wound healing, can be widely used in clinical treatment.
Description
Technical field
The present invention relates to a kind of patches, belong to field of pharmaceutical preparations, in particular to a kind of nursing of emergency department with quickly
Hemostatic plaster.
Background technique
Patch refer to for article major ingredient except auxiliary category material, a critical function of modern wound patch is it
Instead of the critical function of damaged skin, and act on always to wound healing and skin lesion healing.It is (such as dirty that it can resist mechanical factor
Object, collision, inflammation etc.), resist pollution and chemical stimulation；Prevent two degree of infection；Preventing dry and body fluid from losing, (electrolyte is lost
It loses)；Prevent heat from losing；Wound healing process is actively influenced by debridement, creates the microenvironment for promoting wound healing.However it is existing
In use, haemostatic effect is poor for some patches, slows down speed of wound healing, while easily causing superinfection.
Cattail pollen, Chinese medicine name.For Typhaceae plant raupo cattail Typha angustifolia L., typha orientalis Typha
The dry pollen of orientalis Presl or congener.With hemostasis, stagnation resolvation, treating stranguria effect.Shennong's Herbal: trusted subordinate's bladder is cold
Heat, diuresis, hemostasis, dispersing blood stasis blood.Long term usage is made light of one's life by commiting suicide benefiting energy, macrobiosis angle.
Rhizoma imperatae, Chinese medicine name.For gramineae plant cogongrass ImperatacylindricaBeauv.var.major (Nees)
C.E.Hubb. dry rhizome.With cooling blood and hemostasis, reducing fever and causing diuresis effect.Shennong's Herbal: internal lesion caused by overexertion void is thin, tonifying middle-Jiao and Qi, removes the stasis of blood
Blood, blood close fever and chills, diuresis.
Honeysuckle also known as honeysuckle (scientific name: Lonicera japonica)." honeysuckle " one comes from Compendium of Material Medica, by
Just open in honeysuckle flowers as white, after switch to yellow, hence obtain one's name honeysuckle.Medicinal material honeysuckle is Caprifoliaceae woodbine honeysuckle
And congener dry flower or with the flower just opened.Honeysuckle is known as clearing heat and detoxicating good medicine from ancient times.The sweet cold air fragrance of its property,
For clear heat with drugs of sweet flavour and cold nature without injuring one's stomach, fragrance reaches thoroughly again can eliminating evil.Honeysuckle can dispelling wind-heat, also kind removing summer-heat blood poison is used for various heat
Venereal disease, such as body heat, dermexanthesis, macular eruption, heat toxin sore carbuncle, abscess of throat disease, equal significant effect.Modern study proves that honeysuckle contains
Have the pharmacological components such as chlorogenic acid, cyanidenon glycosides, to the various pathogens such as hemolytic streptococcus, Staphylococcus aureus and on
Respiratory tract infection Causative virus etc. has stronger restraint, in addition can also strengthen immunity, Robust speaker feature, protect liver, it is antitumor, disappear
Scorching, antipyretic, hemostasis (blood coagulation), inhibition intestinal absorption cholesterol etc..
Summary of the invention
The present invention provides a kind of emergency department's nursing quick-acting haemostatic powder patch, is matched using a variety of drugs with styptic activity
5, hemostasis is rapid, lasting medicine, and can promote wound healing, can be widely used in clinical treatment.
Specifically, a kind of emergency department's nursing quick-acting haemostatic powder patch of the present invention, by back sheet, carries medicine adhesive layer and adherent layer
Composition carries medicine adhesive layer and is made of the raw material of following parts by weight: 0.01-0.5 parts of vitamin K1, para-amino-methyl-benzoic acid 0.01-0.5
Part, 0.01-0.5 parts of adrenobazonum, 10-25 parts of carboxymethyl chitosan, 10-20 parts of Honegsukle flower P.E, cogongrass rhizome extractive 10-20
Part, 10-20 parts of Pollen Tyjphae extract, 10-30 parts of hydroxypropyl methyl cellulose, 10-20 parts of pressure sensitive adhesive, 5-15 parts of glycerol, deionization
20-50 parts of water.
In a specific embodiment of the invention, life is tieed up in a kind of emergency department nursing quick-acting haemostatic powder patch
Plain K1, para-amino-methyl-benzoic acid, adrenobazonum weight proportion be 2:1:2.
In a specific embodiment of the invention, the load medicine adhesive layer is made of the raw material of following parts by weight: dimension
Raw K10.5 parts of element is 0.25 part of para-amino-methyl-benzoic acid, 0.5 part of adrenobazonum, 20 parts of carboxymethyl chitosan, 15 parts of Honegsukle flower P.E, white
15 parts of MAOGEN extract, 15 parts of Pollen Tyjphae extract, 20 parts of hydroxypropyl methyl cellulose, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, deionization
30 parts of water.
In a specific embodiment of the invention, the load medicine adhesive layer is made of the raw material of following parts by weight: dimension
Raw 0.2 part of K1 of element is 0.1 part of para-amino-methyl-benzoic acid, 0.2 part of adrenobazonum, 10 parts of carboxymethyl chitosan, 12 parts of Honegsukle flower P.E, white
12 parts of MAOGEN extract, 12 parts of Pollen Tyjphae extract, 25 parts of hydroxypropyl methyl cellulose, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, deionization
30 parts of water.
In a specific embodiment of the invention, the load medicine adhesive layer is made of the raw material of following parts by weight: dimension
Raw 0.3 part of K1 of element, 0.15 part of para-amino-methyl-benzoic acid, 0.3 part of adrenobazonum, 25 parts of carboxymethyl chitosan, 20 parts of Honegsukle flower P.E,
20 parts of cogongrass rhizome extractive, 20 parts of Pollen Tyjphae extract, 30 parts of hydroxypropyl methyl cellulose, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, go from
30 parts of sub- water.
In a specific embodiment of the invention, Honegsukle flower P.E, cogongrass rhizome extractive, Pollen Tyjphae extract weight
Amount proportion is 1:1:1.
In a specific embodiment of the invention, the preparation method of the Honegsukle flower P.E includes following step
It is rapid: the 5-10 times of deionized water measured is added in traditional Chinese medicine honeysuckle, refluxing extraction 3 times under the conditions of 50-70 DEG C are 1-3 hours each,
Filter residue is spare, merging filtrate, crushed after being dried, and get dry extract powder 1；The 5-10 times of ethanol solution for measuring 50-70% is added in filter residue, turns
It moves in Microwave Extraction Apparatus, under the conditions of 500-800W, extracts 10-30min, filtering obtains extracting solution, crushed after being dried obtains dry
Cream powder 2, merge dried cream powder 1 and dried cream powder 2 to get.
In a specific embodiment of the invention, the preparation method of the cogongrass rhizome extractive includes: by cogongrass
The ethanol solution of the 5-10 times of 50-70% measured, refluxing extraction 3 times under the conditions of 50-70 DEG C, each 1-3 is added in root herb coarse powder
Hour, filter residue is spare, merging filtrate, crushed after being dried, and get dry extract powder 1；5-10 times is added in filter residue to measure in deionized water, is shifted
Into Microwave Extraction Apparatus, under the conditions of 500-800W, 10-30min is extracted, filtering obtains extracting solution, crushed after being dried gets dry extract
Powder 2, merge dried cream powder 1 and dried cream powder 2 to get.
In a specific embodiment of the invention, the preparation method of the Pollen Tyjphae extract includes: to add cattail pollen
The ethanol solution for entering the 60-80% that 5-10 times is measured, refluxing extraction 3 times under the conditions of 50-70 DEG C are 1-3 hours each, merge filter
Liquid, dry, pulverize get dry extract powder to get
In the present invention, commercial product is can be used in Honegsukle flower P.E, cogongrass rhizome extractive and Pollen Tyjphae extract.
The preparation method of patch of the present invention can use the preparation method of this field routine, such as by the vitamin of recipe quantity
K1, para-amino-methyl-benzoic acid, adrenobazonum, carboxymethyl chitosan, Honegsukle flower P.E, cogongrass rhizome extractive, Pollen Tyjphae extract, hydroxypropyl
Methylcellulose, pressure sensitive adhesive, glycerol and deionized water mixing, using homogenizer homogenous disperse 30-60min, are applied to backing materials
On material, heating, drying, then adherent layer is covered, size is cut as needed, is sterilized, packaging.
Specific embodiment
Embodiment 1:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.5 part of vitamin K1,0.25 part of para-amino-methyl-benzoic acid, and 0.5 part of adrenobazonum, carboxylic first
20 parts of base enclosure glycan, 15 parts of Honegsukle flower P.E, 15 parts of cogongrass rhizome extractive, 15 parts of Pollen Tyjphae extract, hydroxypropyl methyl fiber
20 parts, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, 30 parts of deionized water of element；
By the vitamin K1 of recipe quantity, para-amino-methyl-benzoic acid, adrenobazonum, carboxymethyl chitosan, Honegsukle flower P.E, rhizoma imperatae
Extract, Pollen Tyjphae extract, hydroxypropyl methyl cellulose, pressure sensitive adhesive, glycerol and deionized water mixing, using homogenizer homogeneous
Disperse 40min, be applied on back lining materials, heating, drying, then cover adherent layer, size is cut as needed, is sterilized, packaging；Its
Described in Honegsukle flower P.E, cogongrass rhizome extractive, Pollen Tyjphae extract use commercial product.
Embodiment 2:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.2 part of vitamin K1,0.1 part of para-amino-methyl-benzoic acid, and 0.2 part of adrenobazonum, carboxylic first
10 parts of base enclosure glycan, 12 parts of Honegsukle flower P.E, 12 parts of cogongrass rhizome extractive, 12 parts of Pollen Tyjphae extract, hydroxypropyl methyl fiber
25 parts, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, 30 parts of deionized water of element；
Wherein the preparation method of the Honegsukle flower P.E includes the following steps: that 10 times of amounts for traditional Chinese medicine honeysuckle are added
Deionized water, the refluxing extraction 3 times under the conditions of 60 DEG C, 2 hours every time, filter residue was spare, merging filtrate, crushed after being dried, obtained dry
Cream powder 1；The ethanol solution of 10 times of amounts 60% is added in filter residue, is transferred in Microwave Extraction Apparatus, under the conditions of 600W, extraction
20min, filtering, obtains extracting solution, and crushed after being dried, get dry extract powder 2, merge dried cream powder 1 and dried cream powder 2 to get；
Wherein the preparation method of the cogongrass rhizome extractive includes: that rhizoma imperatae medicinal material coarse powder is added the 70% of 10 times of amounts
Ethanol solution, the refluxing extraction 3 times under the conditions of 60 DEG C, 2 hours every time, filter residue was spare, merging filtrate, and crushed after being dried obtains
Dried cream powder 1；It is added in 6 times of amount deionized waters, is transferred in Microwave Extraction Apparatus in filter residue, under the conditions of 600W, extract 20min,
Filtering, obtains extracting solution, and crushed after being dried, get dry extract powder 2, merge dried cream powder 1 and dried cream powder 2 to get；
Wherein the preparation method of the Pollen Tyjphae extract includes: 70% ethanol solution that cattail pollen is added to 8 times of amounts,
Refluxing extraction 3 times under the conditions of 60 DEG C, 2 hours every time, merging filtrate, dry, pulverize get dry extract powder to get；
By the vitamin K1 of recipe quantity, para-amino-methyl-benzoic acid, adrenobazonum, carboxymethyl chitosan, Honegsukle flower P.E, rhizoma imperatae
Extract, Pollen Tyjphae extract, hydroxypropyl methyl cellulose, pressure sensitive adhesive, glycerol and deionized water mixing, using homogenizer homogeneous
Disperse 60min, be applied on back lining materials, heating, drying, then cover adherent layer, size is cut as needed, is sterilized, packaging.
Embodiment 3:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.3 part of vitamin K1,0.15 part of para-amino-methyl-benzoic acid, and 0.3 part of adrenobazonum, carboxylic first
25 parts of base enclosure glycan, 20 parts of Honegsukle flower P.E, 20 parts of cogongrass rhizome extractive, 20 parts of Pollen Tyjphae extract, hydroxypropyl methyl fiber
30 parts, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, 30 parts of deionized water of element；Wherein the Honegsukle flower P.E, cogongrass rhizome extractive,
Pollen Tyjphae extract uses commercial product；
By the vitamin K1 of recipe quantity, para-amino-methyl-benzoic acid, adrenobazonum, carboxymethyl chitosan, Honegsukle flower P.E, rhizoma imperatae
Extract, Pollen Tyjphae extract, hydroxypropyl methyl cellulose, pressure sensitive adhesive, glycerol and deionized water mixing, using homogenizer homogeneous
Disperse 30min, be applied on back lining materials, heating, drying, then cover adherent layer, size is cut as needed, is sterilized, packaging.
Comparative example 1:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.5 part of vitamin K1,0.25 part of para-amino-methyl-benzoic acid, and 0.5 part of adrenobazonum, carboxylic first
20 parts of base enclosure glycan, 15 parts of Honegsukle flower P.E, 30 parts of Pollen Tyjphae extract, 20 parts of hydroxypropyl methyl cellulose, 15 parts of pressure sensitive adhesive,
10 parts of glycerol, 30 parts of deionized water；
The preparation method is the same as that of Example 1.
Comparative example 2:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.5 part of vitamin K1,0.25 part of para-amino-methyl-benzoic acid, and 0.5 part of adrenobazonum, carboxylic first
20 parts of base enclosure glycan, 15 parts of Honegsukle flower P.E, 30 parts of cogongrass rhizome extractive, 20 parts of hydroxypropyl methyl cellulose, pressure sensitive adhesive 15
Part, 10 parts of glycerol, 30 parts of deionized water；
The preparation method is the same as that of Example 1.
Comparative example 3:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.5 part of vitamin K1,0.75 part of adrenobazonum, and 20 parts of carboxymethyl chitosan, gold
15 parts of honeysuckle flower extract, 15 parts of cogongrass rhizome extractive, 15 parts of Pollen Tyjphae extract, 20 parts of hydroxypropyl methyl cellulose, pressure sensitive adhesive 15
Part, 10 parts of glycerol, 30 parts of deionized water；
The preparation method is the same as that of Example 1.
Comparative example 4:
A kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine back sheet, load medicine adhesive layer and adherent layer
Adhesive layer is made of the raw material of following parts by weight: 0.75 part of vitamin K1,0.25 part of para-amino-methyl-benzoic acid, and carboxymethyl chitosan 20
Part, it is 15 parts of Honegsukle flower P.E, 15 parts of cogongrass rhizome extractive, 15 parts of Pollen Tyjphae extract, 20 parts of hydroxypropyl methyl cellulose, pressure-sensitive
15 parts of glue, 10 parts of glycerol, 30 parts of deionized water；
The preparation method is the same as that of Example 1.
Embodiment 4: the haemostatic effect of mouse docking experiment
Use Kun Ming mice for experimental animal, 80, weight 30-35g.Be divided into 8 groups: blank group, positive controls,
Example 1 group, 2 groups of embodiment, 1 group of comparative example, 2 groups of comparative example, 3 groups of comparative example, 4 groups of comparative example, mouse are consolidated by every group 10
It is scheduled in mouse fixing device, sterilizes mousetail end with alcohol swab, cut with sharp scissors and cut at Mouse Tail-tip 1cm, had
Blood flow goes out.Each experimental group carries out lower column processing: (1) blank group notch exposure；(2) positive controls closely stick at docking
The Wound plaster of yannan Baiyao of 1cm × 1cm；(3) remaining each rent closely sticked at docking 1cm × 1cm above embodiments 1-2 and
The hemostatic plaster of comparative example 1-4 preparation.Bleeding at mouse docking is observed in experiment, every 10s sucks wound with filter paper and seeps
Blood records bleeding stopping period until stopped bleeding.
The haemostatic effect of the hemostatic plaster of the present invention of table 1
It is in table 1 statistics indicate that, hemostatic plaster of the invention can stop blooding rapidly, and each component is mutually assisted in the present invention
Together, anastalsis is played jointly, omits cogongrass rhizome extractive, Pollen Tyjphae extract, para-amino-methyl-benzoic acid or adrenobazonum meeting therein
Haemostatic effect is caused to decline；And the data of table 1, which are also shown that, extracts honeysuckle, rhizoma imperatae and cattail pollen effect using ad hoc approach
It is better than using commercial goods.
The experiment of 5 wound healing of embodiment
Experimental animal uses male Wistar rat 60, weight 200g or so, is divided into 7 groups: blank group, positive control
Group, 2 groups of embodiment, 1 group of comparative example, 2 groups of comparative example, 3 groups of comparative example, 4 groups of comparative example, every group 10.8% sulphur of rat back
Change the depilation of sodium liquid, anaesthetize afterwards for 24 hours, then scalded with 80 DEG C of water-baths and cause within 15 seconds the depth II degree skin scald of rat back 10%, after wound
5mL physiological saline is given through abdominal cavity.Blank group is by hospital gauze flap coverage, and positive controls are using Yunnan Baiyao covering wound
Face, remaining each group is respectively by embodiment 2 and the resulting hemostatic plaster flap coverage of comparative example 1-4.Each determining time point surveys after wound
Wound healing rate: first tracing the surface of a wound on onionskin, then as template, homogeneous hard paper is cut into same big
It is small, it then weighs in the balance, surface of a wound size is indirectly indicative with cardboard sheet weight.Wound healing rate is calculated as follows: wound
Face healing rate (%)=(original surface of a wound area-do not heal surface of a wound area)/original surface of a wound area.
Influence of the hemostatic plaster of the present invention of table 2 to Wound healing rate
Table 2 statistics indicate that, patch of the invention can promote wound healing.
Claims (1)
1. a kind of emergency department's nursing quick-acting haemostatic powder patch, is made of, the load medicine glue back sheet, load medicine adhesive layer and adherent layer
Adhesion coating is made of the raw material of following parts by weight: 0.2 part of vitamin K1,0.1 part of para-amino-methyl-benzoic acid, and 0.2 part of adrenobazonum, carboxymethyl
10 parts of chitosan, 12 parts of Honegsukle flower P.E, 12 parts of cogongrass rhizome extractive, 12 parts of Pollen Tyjphae extract, hydroxypropyl methyl cellulose
25 parts, 15 parts of pressure sensitive adhesive, 10 parts of glycerol, 30 parts of deionized water；
Wherein the preparation method of the Honegsukle flower P.E include the following steps: for traditional Chinese medicine honeysuckle to be added 10 times of amounts go from
Sub- water, the refluxing extraction 3 times under the conditions of 60 DEG C, 2 hours every time, filter residue was spare, merging filtrate, crushed after being dried, and get dry extract powder
1；The ethanol solution of 10 times of amounts 60% is added in filter residue, is transferred in Microwave Extraction Apparatus, under the conditions of 600W, extracts 20min, mistake
Filter, obtains extracting solution, and crushed after being dried, get dry extract powder 2, merge dried cream powder 1 and dried cream powder 2 to get；
Wherein the preparation method of the cogongrass rhizome extractive includes: that rhizoma imperatae medicinal material coarse powder is added to 70% second of 10 times of amounts
Alcoholic solution, the refluxing extraction 3 times under the conditions of 60 DEG C, 2 hours every time, filter residue was spare, merging filtrate, and crushed after being dried gets dry extract
Powder 1；It is added in 6 times of amount deionized waters, is transferred in Microwave Extraction Apparatus in filter residue, under the conditions of 600W, extract 20min, filter,
Extracting solution, crushed after being dried, get dry extract powder 2, merge dried cream powder 1 and dried cream powder 2 to get；
Wherein the preparation method of the Pollen Tyjphae extract includes: 70% ethanol solution that cattail pollen is added to 8 times of amounts, at 60 DEG C
Under the conditions of refluxing extraction 3 times, 2 hours every time, merging filtrate, dry, pulverize get dry extract powder to get；
The vitamin K1 of recipe quantity, para-amino-methyl-benzoic acid, adrenobazonum, carboxymethyl chitosan, Honegsukle flower P.E, rhizoma imperatae are extracted
Object, Pollen Tyjphae extract, hydroxypropyl methyl cellulose, pressure sensitive adhesive, glycerol and deionized water mixing, using homogenizer homogenous disperse
60min is applied on back lining materials, heating, drying, then covers adherent layer, and size is cut as needed, is sterilized, packaging.
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| CN201610060070.5A CN105561000B (en) | 2016-01-29 | 2016-01-29 | A kind of emergency department's nursing quick-acting haemostatic powder patch |
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| CN201610060070.5A CN105561000B (en) | 2016-01-29 | 2016-01-29 | A kind of emergency department's nursing quick-acting haemostatic powder patch |
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| CN105561000B true CN105561000B (en) | 2019-04-26 |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106266717A (en) * | 2016-09-24 | 2017-01-04 | 徐静 | A kind of emergency department nursing efficient quick-acting haemostatic powder patch and preparation method thereof |
| CN109908275A (en) * | 2019-03-11 | 2019-06-21 | 泗水县人民医院 | A kind of emergency department's nursing efficient quick-acting haemostatic powder patch and preparation method thereof |
| CN110269891B (en) * | 2019-08-01 | 2021-06-22 | 河南科技大学第一附属医院 | A kind of quick hemostatic patch for nursing in emergency department and preparation method thereof |
| CN111513796B (en) * | 2020-04-30 | 2021-03-23 | 常州市第一人民医院 | An automatic decompression radial artery hemostat |
| CN114159229A (en) * | 2020-09-11 | 2022-03-11 | 曹兆铭 | Special dressing for cancerous wound |
| CN112245410A (en) * | 2020-09-23 | 2021-01-22 | 徐州融创新材料技术研究院有限公司 | Hemostatic tablet and production method thereof |
| CN115738371A (en) * | 2022-12-05 | 2023-03-07 | 山东柳新堂健康产业有限公司 | Subcritical double-solvent extraction method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435263A (en) * | 2003-03-05 | 2003-08-13 | 成都拓泰医药科技开发有限公司 | Hematostatic gel |
| CN101584721A (en) * | 2009-07-06 | 2009-11-25 | 江苏泰灵生物科技有限公司 | Chinese traditional medicine antibiotic hemostatic plaster |
| CN103356827A (en) * | 2013-07-26 | 2013-10-23 | 重庆金老虎科技开发有限公司 | Cattail pollen adhesive bandage and preparation method thereof |
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2016
- 2016-01-29 CN CN201610060070.5A patent/CN105561000B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435263A (en) * | 2003-03-05 | 2003-08-13 | 成都拓泰医药科技开发有限公司 | Hematostatic gel |
| CN101584721A (en) * | 2009-07-06 | 2009-11-25 | 江苏泰灵生物科技有限公司 | Chinese traditional medicine antibiotic hemostatic plaster |
| CN103356827A (en) * | 2013-07-26 | 2013-10-23 | 重庆金老虎科技开发有限公司 | Cattail pollen adhesive bandage and preparation method thereof |
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