CN105557706B

CN105557706B - A kind of active ingredient compositions

Info

Publication number: CN105557706B
Application number: CN201410546399.3A
Authority: CN
Inventors: 罗昌炎; 詹姆斯·T·布里斯托
Original assignee: Jiangsu Rotam Chemical Co Ltd
Current assignee: Jiangsu Rotam Chemical Co Ltd
Priority date: 2014-10-16
Filing date: 2014-10-16
Publication date: 2018-05-15
Anticipated expiration: 2034-10-16
Also published as: CN105557706A

Abstract

The present invention relates to agriculture field, and in particular to a kind of active ingredient compositions, particularly a kind of insecticidal and bactericidal composition containing Tebuconazole and pymetrozine and its application.A kind of active ingredient compositions contain Tebuconazole and pymetrozine, wherein, the weight ratio of Tebuconazole and pymetrozine is 100:1 to 1:100.The invention further relates to comprising aforesaid active principles in combination thing and the agriculturally insecticidal and bactericidal composition of acceptable auxiliary agent and/or carrier, and the method and purposes of the composition for preventing and controlling agricultural pathogen and/or agricultural pests.

Description

A kind of active ingredient compositions

Technical field

The present invention relates to agriculture field, and in particular to a kind of active ingredient compositions, particularly one kind contain The insecticidal and bactericidal composition and its application of Tebuconazole and pymetrozine.

Background technology

The prevention of agricultural pest is always the problem of being concerned about the most in agricultural production and is important.The whole Growing season of crop It can nearly all be attacked be subject to various diseases and insect pest.For the prevention and control of plant diseases, pest control of crop, conventional way is disease hair at present Raw to apply fungicide, applying pesticide occurs for insect pest, i.e., the strategy that pest and disease damage is individually prevented is this undoubtedly to increase medication time Number.Accordingly, there exist the demand for improving current medication custom.

Tebuconazole (Tebuconazol, Cas.NO：107534-96-3) sterling is clear crystal, is a kind of efficient, wide Spectrum, absorbability triazole type sterilization pesticide, have and protect, treat, rooting out three zones, wide sterilization spectrum, lasting period length, at first by moral Beyer Co., Ltd of state developed in 1986.Tebuconazole can be used as foliar spray agent and seed treatment, its wide sterilization spectrum, work Property it is high, the lasting period is long, many crops are included with monocotyledon and dicotyledon safety.It is mainly used to prevent wheat, flower A variety of fungal diseases on the crops such as life, vegetables, banana, apple, pears and corn and Chinese sorghum, its 60 in more than 50 countries in the whole world Registration and extensive use are obtained in various crop, generally to Erysiphe, Puccinia, beak genuss, nuclear cavity Pseudomonas and septoria musiva Category etc. disease caused by a variety of pathogens can be prevented effectively.

Pymetrozine (Pymetrozine, Cas.NO：123312-89-0) pymetrozine belongs to pyridines or Triazinone desinsection Agent, was developed by Ciba-Geigy company of Switzerland in 1988 earliest.Pymetrozine has pest action of contace poison, while also has interior inhale to live Property.Can also can be in phloem transport in xylem transporting in plant；Therefore it both can be used as foliar spray, it can also be used to soil Earth processing.The product shows the sucking pest of various crop excellent prevention effect, can be widely used for crop, fruit Prevent the eliminate aphis various pests such as section, Delphacidae, Aleyrodidae, Cicadellidae, such as wild cabbage on the agricultural such as tree, vegetables and tealeaves and gardening Aphid, cotten aphid, wheat aphid, black peach aphid, small green statin leafhopper, brown paddy plant hopper, small brown rice planthopper, white backed planthopper, sweet potato whitefly and greenhouse whitefly etc..

The problem of pesticide and pestsides synthesis are one more complicated, scientific and reasonable mixture, can play and improve work efficiency, drug effect Purpose；Blindly mix, then can reduce drug effect, or even cause poisoning.And not all pesticide can mix, such as organophosphor Class pesticide cannot with the combined use of pesticides containing copper agent, such as dithiocarbamate fungicide, 2,4-D salts herbicide and copper Preparation is used with, because being complexed with copper ion, and is lost activity, microbial source insecticide and Nankor cannot be with killing Microbial inoculum is used with etc..

At present, it is less for different type pesticide such as insecticide and bactericide compounded research, study also most Rest on bucket to mix or the level of simple combination, this combination is in addition to times for spraying is reduced, in the prevention to pest and disease damage In have no synergistic effect.Therefore, it is previous new that research and development are mutually promoted, the insecticidal and bactericidal composition that mutually cooperates with becomes mesh Research direction.

The content of the invention

The present invention seeks to provide a kind of active ingredient compositions for above-mentioned shortcoming, the active ingredient contains penta Azoles alcohol and pymetrozine.

To solve the above-mentioned problems, the present inventor have passed through long-term research, find after Tebuconazole and Pyraphione compound, Potentiation can be produced each other, i.e. the presence of Tebuconazole can increase the insecticidal effect of pymetrozine, the presence of same pymetrozine Also the bactericidal effect of Tebuconazole can be promoted, the two is mutually promoted, and is based on the discovery, and inventor completes the present invention.

A kind of active ingredient compositions of the present invention are to take following technical scheme to realize：

A kind of active ingredient compositions, contain Tebuconazole and pymetrozine.

In aforesaid active principles in combination thing, the weight ratio of the Tebuconazole and pymetrozine can be 100:1 to 1:100. Preferably, the weight ratio of the Tebuconazole and pymetrozine is 50:1 to 1:50, the weight of the preferred Tebuconazole and pymetrozine Amount is than being 1:20 to 20:1；Further preferably 1:10 to 10:1, particularly preferred 1:5 to 5:1.

Another aspect of the present invention provides a kind of insecticidal and bactericidal composition, wherein the composition includes above-mentioned active ingredient group Compound, and agriculturally acceptable auxiliary agent and/or carrier.

Preferably, in a kind of above-mentioned insecticidal and bactericidal composition, the active ingredient compositions are in the pesticide-germicide group Weight content in compound is 1wt.% to 80wt.%, preferably 10wt.% to 60wt.%, more preferably 10wt.% to 50wt.%.

A kind of above-mentioned insecticidal and bactericidal composition is prepared into agriculturally acceptable any formulation, wherein being preferably prepared to suspend Agent, aqueous emulsion, microemulsion, water dispersible granules, wettable powder, suspension seed-coating agent, granule, microcapsule suspending agent etc..

Above-mentioned formulation is this area regular dosage form, what its preparation method was well known to those skilled in the art, is prepared into Agricultural agent and/or carrier and its dosage used in above-mentioned various formulations are similarly well-known to those skilled in the art, this It may refer to for example a bit《Formulations of pesticide processing technology》（Liu Bulin is edited, the second edition）.Auxiliary agent used and/or carrier are for example Including but not limited to solvent, cosolvent, emulsifying agent, dispersant, wetting agent, cyst material, adhesive, film forming agent, disintegrant, increasing Thick dose, antifreezing agent, stabilizer, pH adjusting agent, warning coloration, filler and/or carrier etc..Those skilled in the art can select it In one or more auxiliary agents and/or carrier.

For example, when being prepared into suspending agent, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, wetting agent 2-10%, dispersant 2-10%, thickener 1-5%, antifreezing agent 1-5%, defoamer 0.1-2%, water surplus；

When being prepared into aqueous emulsion, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, solvent and cosolvent 2-20%, emulsifying agent 1-10%, antifreezing agent 1-5%, defoamer 0.1-2%, water surplus；

When being prepared into wettable powder, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, wetting agent 2- 10%th, dispersant 2-10%, filler surplus；

When being prepared into suspension seed-coating agent, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, wetting agent 2- 10%th, dispersant 2-10%, thickener 1-5%, film forming agent 1-5%, antifreezing agent 1-5%, defoamer 0.1-2%, warning coloration 0.1-2%, water Surplus；

When being prepared into microemulsion, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, solvent and cosolvent 2-20%, emulsifying agent 5-20%, antifreezing agent 1-5%, defoamer 0.1-2%, water surplus；

When being prepared into water dispersible granules, following components by weight percent can be included：Tebuconazole+pymetrozine 1-80%, wetting agent 2- 10%th, dispersant 2-10%, disintegrant 1-5%, adhesive 1-5%, filler surplus.

Wherein, in above-mentioned formula, the solvent can be selected：Benzene,toluene,xylene, acetone, dimethylformamide, Dimethyl sulfoxide (DMSO), chloroform, dichloromethane, hexamethylene, cyclohexanone, 1-methyl-2-pyrrolidinone, methanol, ethanol, propyl alcohol, isopropyl It is alcohol, butanol, isobutanol, cyclohexanol, Propylene Glycol ether, ethohexadiol ether, petroleum ether, acetonitrile, paraffin, tetrahydronaphthalene, different One or more in phorone, soybean oil, cottonseed oil etc.；

The cosolvent can be selected：One or more in methanol, ethanol, isopropanol, n-butanol etc.；

The emulsifying agent can be selected：Lauryl sodium sulfate, neopelex, calcium dodecyl benzene sulfonate, Thermally coupled distillation columns amine salt, castor oil polyoxyethylene ether phosphate amine salt, three phenethyl phenol polyoxy ether phosphoric acid Ester amine salt, Polyoxyethylene fatty acid amides fatty acid ester, Fixanol, alkyl isoquinolinium salt, dialkylmorpholinum salts, oleamide sulfonic acid Salt, diisopropyl naphthalene sulfonate, lignosulfonates, naphthalenesulfonate formaldehyde condensation compound, styryl phenyl polyoxyethylene ether, benzene Ethyl -phenol polyoxyethylene poly-oxygen propylene aether, nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, polyoxyethylene alkyl ether, Polyoxyethylene polyoxypropylene block polymer, alkyl phenol formaldehyde resin polyoxyethylene ether, Polyoxyethylene Sorbitol Fatty Acid Esters, mountain In pears alcohol acid anhydride monostearate, sorbitan monostearate polyoxyethylene ether, polyoxypropylene glycol mono fatty acid ester etc. It is one or more；

The dispersant can be selected：Lignosulfonates, p-hydroxyphenyl sodium lignin sulfonate, fatty alcohol polyoxyethylene ether Sulfate, alkylnaphthalene sulfonate, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, dodecyl trimethyl ammonium salt, alkyl dimethyl benzyl ammonium Salt, two polyoxyethylene lauryl ether phosphate, styrene-maleic acid salt copolymer, aliphatic alcohol polyoxyvinethene phosphate, nonyl Base phenol polyethenoxy ether, glycerine fatty acid polyoxyethylene ether, polyoxyethylene alkylaryl ether, polyoxyethylene lanolin alcohol, polyoxy In ethene sorbitan aliphatic ester, polyoxyethylene glyceryl mono fatty acid ester, alkylolamides and polyoxyethylene alkyl amine etc. One or more；

The wetting agent can be selected：Lauryl sodium sulfate, calcium dodecyl benzene sulfonate, isooctanol succinate sulfonic acid Sodium, oleoyl methyl sodium taurocholate, polyoxyethylene lauryl ether carboxylic acid sodium, sodium N-lauroyl sarcosinate, N- lauroyl paddy ammonia Sour sodium, dioctyl sulfosuccinate, polyoxyethylene alkylaryl ether phosphate ester salt, trisiloxanes polyoxyethylene ether, triphen second The poly- base ether formaldehyde contracting of base phenol polyoxyethylene ether, castor oil polyoxyethylene ether, fatty alcohol polyoxyethylene ether, alkylphenol-polyethenoxy Compound, alkylphenol-polyethenoxy base ether phosphate, polyoxyethylene fatty acid ester, higher fatty acid ester, sorbitan fatty One or more in acid esters etc.；

Described adhesive can be selected：It is starch, polyvinylpyrrolidone, carboxymethyl cellulose, carboxyethyl cellulose, bright One or more in glue, Arabic gum, xanthans etc.；

The film forming agent can be selected：Polyvinyl alcohol, polyvinyl acetate, polyacrylamide, carboxymethyl cellulose, hydroxypropyl Base cellulose, Arabic gum, gelatin, xanthans, starch,

The disintegrant can be selected：Urea, sodium sulphate, calcium sulfate, sodium acid carbonate, ammonium sulfate, magnesium chloride, sodium chloride etc. In one or more；

The thickener can be selected：Arabic gum, xanthans, gelatin, polyvinyl alcohol, aluminium-magnesium silicate, carboxymethyl cellulose One or more in plain sodium etc.；

The defoamer can be selected：One or more in butylphosphoric acid ester, phosphoric acid isobutyl ester, n- octanol, silicone etc.；

The antifreezing agent can be selected：One or more in ethylene glycol, propane diols, glycerine etc.；

The stabilizer can be selected：Triphenyl phosphite, N- soybean oleyl trimethylene diamine, dialkyl group succinate One or more in sulfonate, epoxychloropropane, butyl glycidyl ether etc.；

The warning coloration can be selected：Basic rhodamine, alkaline purple 10, alkalescence purple 49, CI 45430, acid red 52, acid One or more in property red 14, acid blue 9, acid yellow 23, alkali red 1:1 0, alkali red 1:1 08；

The preservative can be selected：One or more in benzoic acid, sodium benzoate etc.；

The pH adjusting agent can be selected：Hydrochloric acid, calgon, sodium citrate, sodium acid carbonate, sodium hydroxide, hydrogen-oxygen One or more in agent, triethanolamine etc.；

The filler and/or carrier can be selected：Attapulgite, diatomite, kaolin, white carbon, bentonite, illiteracy are de- One or more in stone, calcium carbonate, zeolite, acid clay, carclazyte, pyrophyllite, talcum, calcite etc..

Another aspect of the present invention provides aforesaid active principles in combination thing or insecticidal and bactericidal composition is used to prevent or control agriculture The purposes of industry pest and disease damage.

Wherein, applicable crops include but not limited to：Rice, wheat, corn, barley, rye, oat, sorghum, cotton, Soybean, red bean, Kidney bean, peanut, buckwheat, beet, rape, sunflower, sugarcane, tobacco, eggplant, tomato, Chinese prickly ash, potato, Cucurbita pepo, cucumber, pumpkin, watermelon, wax gourd, pumpkin, radish, root-mustard, Chinese cabbage, wild cabbage, leaf mustard, broccoli, cauliflower, ox Burdock, garland chrysanthemum, jerusalem artichoke, romaine lettuce, shallot, onion, garlic, asparagus, carrot, caraway, celery, spinach, Swiss chard, rape etc..

The disease includes but not limited to：Wheat class disease such as rust（Leaf rust, bar rust, puccinia graminis）, head blight, powdery mildew, line Blight, glume blight, full rot, root rot and basal stem rot, smut（Bunt, smut）；Maize diseases such as leaf blight, Helminthosporium maydis, brown spot, head smut, stem rot, bacterial wilt, rust, banded sclerotial blight, smut；It is cotton disease such as samping off, vertical withered Disease, anthracnose, droop, verticillium wilt, cotton boll blight, boll rot of cotton；Rice disease such as bakanae disease, rice blast, false smut, line Blight, leaf blight；Rape disease such as sclerotiniose, powdery mildew, gall of tea etc.；Sorghum disease such as head smut etc.；Soybean diseases are such as Rust, samping off, damping-off, anthracnose, leaf spot, downy mildew, ring spot, sclerotiniose etc.；Tomato disease such as tomato stands withered Disease, early blight of tomato, tomato late blight, graw mold of tomato, sclerotinia of tomato, tomato verticillium wilt, tomato powdery mildew etc.；Cucumber disease Evil is such as cucumber rhizoctonia rot, cucumber sickle-like bacteria withers, cucumber blight dis-ease, cucumber downy mildew, Cucumber Blight, scab of cucumber, cucumber Gray mold, cucumber anthracnose, cucumber spot disease, cucumber timberrot, powdery mildew of cucumber, angular leaf spot etc.；Eggplant disease such as eggplant Sub- Phomopisis vexans, eggplant anthracnose, eggplant verticillium wilt, wilt of eggplant, eggplant root rot, eggplant sclerotiniose, eggplant cotton disease, eggplant Sub- powdery mildew, grey mould of egg plant, eggplant mildew disease etc.；Tobacco diseases for example Tobacco seedling diseases, tobacco damping-off, tobacco black shank, Anthracnose of tobacco, tobacco droop, tobacco downy mildew, tobacco black lowering, tobacco leaf spot, tobacco sclerotiniose, tobacco sky shin Disease, tobacco southern blight, Powdery Mildew in Tobacco, Alternaria alternate, anthracnose of tobacco, tobacco black spot etc..It is each that other can also be prevented A variety of fungal diseases on kind vegetable crop, such as scab, downy mildew, soft rot, leaf spot, leaf mold, powdery mildew, anthrax Disease, head blight, gray mold, epidemic disease, powdery mildew, sclerotiniose, rust, droop etc..

The pest includes Lepidoptera, Diptera, coleoptera, Homoptera, Orthoptera, Hymenoptera, Isoptera, Siphonaptera, roach The agricultural pests such as Lian mesh, Thysanoptera.

The pest of the coleoptera includes but not limited to bean weevil category, Agriotes spp, flower genus, pears as category, cockchafer category, cucumber beetle Category, bean weevil category, day Bos, ceutorhynchus, phyllotreta, Curculio, round end rhinoceros cockchafer category, chrysomelid category, Phytonomus, tooth bark beetle category, powder Moth belongs to, beak is as category, the short beak of rose are as belonging to, eating phyllobranchia cockchafer category, striped flea beetle, root gill cockchafer category, hidden chin as category, bark beetle Category, Sitophilus and Tribolium etc.；

The pest of Diptera includes but not limited to Aedes, Hippelates, by Anastrepha, Anopheles, Bactrocera, small bar reality Fly category, Chrysops, Callitroga, cecidomyiia category, Culex, leaf cecidomyiia category, Delia, Drosophila, Fannia, Hylemyia, spot are dived Fly category, fly category, gadfly category and big uranotaenia；

The pest of Semiptera and/or Homoptera includes but not limited to adelgid, white wheel armored scale category, froghopper category, Aphis, powder Pediculus, lecanium category, snow armored scale category, Aspidiotus category, soft wax a red-spotted lizard category, green jassids category, lepidosaphes shimer, stinkbug category, Lygus Hahn, long tube Aphis, rice green leafhopper category, green rice bug category, froghopper category, Phytocoris, stern line mealybug category, mealybug category, pearl lecanium category, variegation Aphis, Sound Aphis, Triatoma and sharp armored scale category；

The pest of Hymenoptera include but not limited to Myrmecina, leaf ant category, black ant category, Diprion, ant category, Monomorium, Neodiprion, Pogonomyrmex, hornet category, Solenopsis, Vespula and Xylocopa；

The pest of Lepidoptera includes but not limited to Adoxophyessp, volume moth category, thin moth category, straw borer spp, Noctua, bean powder Butterfly category, Crambus Fabricius, Diaphania, snout moth's larva category, Earias, meal moth category, angle sword Noctua, blue or green Eimeria, Heliothis, canopy of the heavens hair Eimeria, thin moth category, moth stem Noctua, Spodoptera, Synanthedon and Yponomeuta；

The pest of Thysanoptera includes but not limited to hard Thrips and Thrips.Specific pest for example can be melonfly, tangerine Small trypetid, invasion trypetid, peach trypetid, the small bar trypetid in Mediterranean, rape leave cecidomyiia, delia platura, anthomyia canicularis, anthomyia scalaris, Gasterophilus intestinalis, Haematobia irritans, heel fly, dish are dived fly, housefly, cotten aphid, soybean aphid, apple aphid, Bemisia argentifolii, sweet potato whitefly, Mei Zhougu Chinch bug, lucid asparagus tubule aphid, brevicoryne brassicae, Diuraphis noxia, citrus psylla, Chinese herbaceous peony rounded tail aphid, eriosoma lanigerum, brown America stinkbug, iS-One Angle fleahopper, tea angle fleahopper, blow cotton a red-spotted lizard, mango yellow line leafhopper, small brown rice planthopper, big Leptocorisa spp, different Leptocorisa spp, lygushesperus, the root of Beijing euphorbia Macrosiphus spp, grain aphid, wheat are without net aphid, black peach aphid, cabbage aphid, rice green leafhopper, green rice bug, brown paddy plant hopper, chaff piece armored scale, black-film shield It is a red-spotted lizard, popcorn wing plant hopper, grape phylloxera, corn leaf aphids, rhopalosiphum padi, olive pearl lecanium, aphid green bugs, grain aphid, white Backward flight lice, greenhouse whitefly, small brown rice planthopper, Bemisia tabaci, Trialeurodes vaporariorum Westwood, leafhopper, rice green leafhopper, rice leaf roller, small sugarcane borer, cotton boll Worm, paddy reality noctuid, tobacco budworm, Hellula undalis, tomato pinworm moth, the white wing open country snout moth's larva of eggplant, lopper worm, beanpod open country snout moth's larva, bag moth, 3 points Water snout moth's larva, autumn geometrid moth, corn borer, apple brown bortrix, cutworm, soybean noctuid, looper, striped rice borer, yellow rice borer, Sesamia inferens, powder The brown slug moth of stem snout moth's larva, copper stain, gelechiid, beet armyworm, diamondback moth, cabbage caterpillar, lopper worm, tobacco budworm, bollworm, the brown Ji of cigarette The hard thrips of horse, Frankliniella occidentalis, greenhouse thrips, tangerine, beans golden thistle horse etc..

The reactive compound Tebuconazole and reactive compound pymetrozine of the present invention can be combined/be administered in combination.Including separate, according to It is secondary or Tebuconazole and pymetrozine is administered simultaneously.Preferably, the Tebuconazole is combined as the group of Tebuconazole and pymetrozine with pymetrozine The form of compound.In the case of separate administration, order of administration does not usually influence the result of control measure.

A kind of method that cover crop is attacked with preventing disease and pest, including make crop and the activity containing Tebuconazole and pymetrozine into It is grouped compound or insecticidal and bactericidal composition contact.

Present invention also offers a kind of prevention or the method for disease and pest control, by the active ingredient compositions of the present invention or kill Worm bactericidal composition acts on target useful plant, target disease and insect or its environment, the propagating materials of target useful plant

The present invention active ingredient compositions or insecticidal and bactericidal composition by using a effective amount of active ingredient processing plant, Plant propagation material, soil, surface, material or space are infected by pest and disease damage to carry out in the past and later.

The active ingredient compositions or insecticidal and bactericidal composition of the present invention prevent various plants for example cereal, water fruits and vegetables, A large amount of pest and disease damages on industrial crops are especially important.

The plant that the active ingredient compositions of the present invention or insecticidal and bactericidal composition are handled can be used to include all gene-modified Plant or genetically modified plants.

A kind of active ingredient compositions or insecticidal and bactericidal composition are used to protect plant propagation material and then grow Plant organ purposes.

Term " plant propagation material " is understood to mean that all generation parts of plant, including seed, root, fruit, block Stem, napiform root, rhizome, branch, seedling bud and other plant part.It also is included in after germination or is moved after emerging from soil The rice shoot and young plant of plant.Plant propagation material can in plantation or transplanting or before use the preventative place of plant protection compound Reason.

The present invention active ingredient compositions or insecticidal and bactericidal composition can be used for protection branch to prevent blade face pest and disease damage with And for seed and root processing to prevent soil pest and disease damage.

Therefore, active ingredient compositions of the invention or insecticidal and bactericidal composition are suitable for seed treatment to protect seed to prevent The only infringement of pest and disease damage, the particularly sick insect pest of soil, and plant roots and the branch of generation are protected to prevent soil pest and disease damage and leaf The infringement of face pest and disease damage.

Preferably, plant propagation material is seed.The method of seed treatment, such as can there are, diluent liquid or solid Seed is directly immersed in the method in liquid condition preparaton made medicament be impregnated with seed by the preparaton of shape without dilution；Will Solid chemicals or liquid preparation are mixed with seed, and being coated processing makes the method for the surface of the seed attachment medicament；Planting The methods of being sprayed while plant near seed.

Beneficial effects of the present invention are shown：

1. the composition of the present invention can be used for various crop or vegetables, a dispenser, entomogenous fungi double play, it is a variety of to prevent crop Disease and insect pest；

2. in the present composition, after Tebuconazole and Pyraphione compound, potentiation, i.e. penta azoles can be produced each other The presence of alcohol can increase the insecticidal effect of pymetrozine, and the presence of same pymetrozine can also promote the bactericidal effect of Tebuconazole, The two is mutually promoted.

Embodiment

The present invention is further described with reference to specific embodiment, but does not limit the invention to these tools Body embodiment.One skilled in the art would recognize that present invention encompasses may include in Claims scope All alternatives, improvement project and equivalents.

（One）Example of formulations

In following example of formulations, unless otherwise indicated, the percentage is weight percentage.

+ 4% pymetrozine water dispersing granule of 1 40% Tebuconazole of embodiment

Formula composition is：Tebuconazole 40%, pymetrozine 4%, fatty alcohol polyoxyethylene ether 4%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%th, sodium sulphate 4%, polyvinylpyrrolidone 5%, kaolin surplus；

Preparation method is：The above-mentioned each component of formula ratio is weighed respectively, and is mixed, is granulated, and water dispersible granules are made.

+ 40% pymetrozine water dispersing granule of 2 4% Tebuconazole of embodiment

Formula composition is：Tebuconazole 4%, pymetrozine 40%, trisiloxanes polyoxyethylene ether 8%, p-hydroxyphenyl lignin sulfonic acid Sodium 7%, ammonium sulfate 4%, xanthans 5%, bentonite surplus；；

+ 20% pymetrozine wettable powder of 3 0.2% Tebuconazole of embodiment

Formula composition is：Tebuconazole 0.2%, pymetrozine 20%, two polyoxyethylene lauryl ether calcium phosphate 6%, dodecyl Benzene sulfonic acid calcium 6%, attapulgite surplus；

Preparation method is：The above-mentioned each component of formula ratio is weighed, and is mixed, grinds, crushes, wettable powder is made Agent.

+ 25% pymetrozine wettable powder of 4 0.5% Tebuconazole of embodiment

Formula composition is：Tebuconazole 0.5%, pymetrozine 25%, oleoyl methyl sodium taurocholate 6%, polyoxyethylene glyceryl list Fatty acid ester 5%, bentonite surplus；

+ 0.1% pymetrozine suspension agent of 5 10% Tebuconazole of embodiment

Formula composition is：Tebuconazole 10%, pymetrozine 0.1%, isooctanol Disodium sulfosuccinate 5%, aliphatic alcohol polyethenoxy Ether phosphate 5%, polyvinyl alcohol 1%, propane diols 5%, silicone 0.5%, water surplus；

Preparation method is：The above-mentioned each component of formula ratio is weighed, by ultramicro grinding method, suspending agent is made.

+ 30% pymetrozine suspension agent of 6 6% Tebuconazole of embodiment

Formula composition is：Tebuconazole 6%, pymetrozine 30%, N- sodium lauroyl glutamates 8%, nonylphenol polyoxyethylene ether 8%th, aluminium-magnesium silicate 3%, ethylene glycol 5%, silicone 0.5%, water surplus；

+ 10% pymetrozine water emulsion of 7 0.1% Tebuconazole of embodiment

Formula composition is：Tebuconazole 20%, pymetrozine 0.1%, dichloromethane 8%, neopelex 8%, ethylene glycol 5%th, butylphosphoric acid ester 0.5%, water surplus；

Preparation method is：Active ingredient, solvent, emulsifying agent etc. are added together, make to be dissolved into homogeneous oil phase；Jiang Shui, prevent Freeze agent, defoamer etc. to mix, into homogeneous water phase.Under high velocity agitation, water is added to oil phase, aqueous emulsion can be made.

+ 20% pymetrozine water emulsion of 8 1% Tebuconazole of embodiment

Formula composition is：Tebuconazole 1%, pymetrozine 20%, dimethylformamide 18%, phenethyl phenol polyoxyethylene polyoxy Propylene ether 10%, ethylene glycol 5%, phosphoric acid isobutyl ester 0.5%, water surplus；

+ 0.5% pymetrozine micron emulsion of 9 25% Tebuconazole of embodiment

Formula composition is：Tebuconazole 25%, pymetrozine 0.5%, dimethylbenzene 10%, ethanol 2%, Polyoxyethylene fatty acid amides fatty acid ester 8%th, ethylene glycol 5%, phosphoric acid isobutyl ester 0.5%, water surplus；

Preparation method is：The above-mentioned each component of formula ratio is weighed, then by pesticide activity component, solvent, cosolvent, surface Activating agent is prepared by mixing into oil phase, and other components are added to the water and are prepared into water phase, then adds oil into water phase while stirring Phase, is made microemulsion.

+ 1% pymetrozine micron emulsion of 10 20% Tebuconazole of embodiment

Formula composition is：Tebuconazole 20%, pymetrozine 1%, 1-methyl-2-pyrrolidinone 13%, methanol 4%, three phenethyl phenols are gathered Oxygen ether phosphate amine salt 12%, glycerine 5%, n- octanol 0.5%, water surplus；

+ 5% pymetrozine suspension seed coat agent of 9 25% Tebuconazole of embodiment

Formula composition is：Tebuconazole 25%, pymetrozine 5%, glycerine fatty acid polyoxyethylene ether 6%, polyoxyethylene lauryl ether Carboxylic acid sodium 6%, gelatin 5%, polyvinyl acetate 4%, ethylene glycol 5%, n- octanol 0.5%, basic rhodamine 0.5%, water surplus；

Preparation method is：Preparation method is：The above-mentioned each component of formula ratio is weighed, by ultramicro grinding method, is made and suspends Seed coat agent.

+ 25% pymetrozine suspension seed coat agent of 10 5% Tebuconazole of embodiment

Formula composition is：Tebuconazole 5%, pymetrozine 25%, styrene-maleic acid salt copolymer 5%, isooctanol succinate Sodium sulfonate 5%, Arabic gum 4%, polyacrylamide 4%, glycerine 5%, n- octanol 0.5%, basic rhodamine 0.5%, water surplus；

11 active ingredient compositions of embodiment

Tebuconazole 40%, pymetrozine 60%, is proportionally uniformly mixed.

（Two）Biological test

When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is administered alone, deposit In synergistic function.So-called " Colby formula " (ginseng can be used in the predictive role of the particular combination of two kinds of reactive compounds See S.R. Colby, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) it is calculated as below:If

X is when the use of dosage being mg/ha or activity during reactive compound A that concentration is mppm；It is expressed as accounting for and does not locate Manage the percentage of control；

Y is when the use of dosage being ng/ha or activity during reactive compound B that concentration is nppm, is expressed as accounting for and does not locate Manage the percentage of control；

E is when the use of dosage being m and n g/ha or work during reactive compound A and B that concentration is m and n ppm Property,

So

If the activity of actual observation is more than expection activity, then said composition surpasses adduction, i.e., with synergistic effect.

1 grey mould fruit rot of strawberry controlling experiment of biological test example

Material to be tested：Strawberry

Controlling object：Gray mold

Test method：Choose healthy strawberry, foliar spray processing carried out with sprayer, 24 it is small when after to be inoculated with strawberry grey Mildew bacterium, experiment set 23 processing and 1 blank control altogether（Blank control sprays equivalent clear water）.Inoculation carries out preventive effect after 7 days Investigation, the result is shown in table 1 below.

Table 1

As can be seen from Table 1, pymetrozine is in itself to graw mold of tomato without any preventive effect, but after being compounded with Tebuconazole, it is right Grey mould fruit rot of strawberry prevention shows obvious synergistic effect.

2 maize head smut controlling experiment of biological test example

Material to be tested：Corn

Controlling object：Head smut

Test method：Soil inoculation germ is used to measure prevention effect.Mixing for corn seed is carried out according to the dosage of table 2 Kind.The seed mixed is sowed after drying.After the soil sieving of field, head smut bacterium powder is added by 0.1%, bacterium soil fully mixes, and opens cave Seed is first put afterwards, and after then stablizing per the morbidity of cave lid bacterium soil 100g. smut of maize, investigation morbidity strain, counts diseased plant rate, meter Calculate prevention effect.

As can be seen from Table 2, pymetrozine is in itself to maize head smut without any preventive effect, but after being compounded with Tebuconazole, Prevention to head smut shows obvious synergistic effect.

3 corn small brown rice planthopper controlling experiment of biological test example

Controlling object：Small brown rice planthopper

Test method：Healthy corn seedling is chosen, small brown rice planthopper is inoculated with, then carries out foliar spray processing with sprayer, its Middle experiment sets 23 processing and 1 blank control altogether（Blank control sprays equivalent clear water）.Dispenser carries out preventive effect investigation after 10 days, The result is shown in table 3 below.

As can be seen from Table 3, Tebuconazole is in itself to small brown rice planthopper without any preventive effect, but with after Pyraphione compound, flying to rice The prevention of lice shows obvious synergistic effect.

4 Corn diseases and insect pests controlling experiment of biological test example

Material to be tested：Corn seed

Controlling object：Maize aphids, head smut

Test method：Respectively with the mixture of Tebuconazole+pymetrozine of the invention, Tebuconazole single dose, Single-dose pymetrozine pair Corn seed is coated processing, and blank control is used as using uncoated corn seed.Then sowed.Wherein test and set 1 altogether A processing, 2 medicament controls, and 1 blank control.Often processing sets 3 repetitions.Later growth period is investigated to head smut With the preventive effect of aphid.The result is shown in table 4 below.

Table 4

Pymetrozine is individually to maize head smut without any preventive effect it can be seen from the result of table 4, and works as itself and Tebuconazole After compounding, virulence of the Tebuconazole to maize head smut can be strengthened, prevention Sporisorium reilianum shows that obvious synergy is made With.Equally, Tebuconazole after it is with Pyraphione compound, can strengthen pymetrozine to aphid individually to maize aphids without any preventive effect The virulence of worm, prevention maize aphids show obvious synergistic effect.Tebuconazole and Pyraphione compound show prevention Corn diseases and insect pests Show obvious synergistic effect.

A kind of insecticidal and bactericidal composition of the present invention is described by specific embodiment.But examples detailed above is only Only be that the present invention is explained further, be not limitation of the invention, by by such scheme carry out it is simple adjust into Obtained from scheme, without departing from the present invention spirit, be regarded as being included within the scope of the present invention.

Claims

1. a kind of active ingredient compositions, it is characterised in that the active ingredient compositions are made of Tebuconazole and pymetrozine, institute The weight ratio for stating Tebuconazole and pymetrozine is 100:1 to 1:100.

A kind of 2. active ingredient compositions according to claim 1, it is characterised in that the weight of the Tebuconazole and pymetrozine Amount is than being 50:1 to 1:50.

A kind of 3. active ingredient compositions according to claim 1, it is characterised in that the weight of the Tebuconazole and pymetrozine Amount is than being 20:1 to 1:20.

A kind of 4. active ingredient compositions according to claim 1, it is characterised in that the weight of the Tebuconazole and pymetrozine Amount is than being 10:1 to 1:10.

A kind of 5. active ingredient compositions according to claim 1, it is characterised in that the weight of the Tebuconazole and pymetrozine Amount is than being 5:1 to 1:5.

6. a kind of insecticidal and bactericidal composition, it is characterised in that the active ingredient compositions as described in claim 1, can agriculturally connect Auxiliary agent and/or the carrier composition received.

7. a kind of insecticidal and bactericidal composition according to claim 6, it is characterised in that the active ingredient compositions are in institute It is 1wt.% to 80wt.% to state the weight content in a kind of insecticidal and bactericidal composition.

8. a kind of insecticidal and bactericidal composition according to claim 6, it is characterised in that the active ingredient compositions are in institute It is 5wt.% to 60wt.% to state the weight content in a kind of insecticidal and bactericidal composition.

9. a kind of insecticidal and bactericidal composition according to claim 6, it is characterised in that the active ingredient compositions are in institute It is 10wt.% to 50wt.% to state the weight content in insecticidal and bactericidal composition.

10. a kind of insecticidal and bactericidal composition according to claim 6, it is characterised in that by the insecticidal and bactericidal composition Be prepared into agriculturally acceptable suspending agent, aqueous emulsion, microemulsion, water dispersible granules, wettable powder, suspension seed-coating agent, Granula, microcapsule suspending agent.

11. a kind of insecticidal and bactericidal composition described in active ingredient compositions or claim 6 described in claim 1 is used for pre- Anti- or control agricultural pest purposes.

A kind of 12. method prevented or control agricultural pest, it is characterised in that by the active ingredient group described in claim 1 A kind of insecticidal and bactericidal composition described in compound or claim 6 act on target useful plant, target disease and insect or its environment, The propagating materials of target useful plant.

13. according to the method for claim 12, it is characterised in that the propagating materials of the useful plant is seed.