CN108419798A - A kind of bactericidal composition and its application containing alkene oxime amine - Google Patents
A kind of bactericidal composition and its application containing alkene oxime amine Download PDFInfo
- Publication number
- CN108419798A CN108419798A CN201710075714.2A CN201710075714A CN108419798A CN 108419798 A CN108419798 A CN 108419798A CN 201710075714 A CN201710075714 A CN 201710075714A CN 108419798 A CN108419798 A CN 108419798A
- Authority
- CN
- China
- Prior art keywords
- alkene oxime
- agent
- disease
- anthracnose
- blight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 alkene oxime amine Chemical class 0.000 title claims abstract description 207
- 239000000203 mixture Substances 0.000 title claims abstract description 162
- 230000000844 anti-bacterial effect Effects 0.000 title description 29
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 85
- 201000010099 disease Diseases 0.000 claims abstract description 83
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 claims abstract description 78
- PZBPKYOVPCNPJY-UHFFFAOYSA-N 1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=C)CN1C=NC=C1 PZBPKYOVPCNPJY-UHFFFAOYSA-N 0.000 claims abstract description 70
- 239000005795 Imazalil Substances 0.000 claims abstract description 70
- 229960002125 enilconazole Drugs 0.000 claims abstract description 70
- XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 claims abstract description 67
- 239000005754 Cyazofamid Substances 0.000 claims abstract description 59
- 239000005868 Metconazole Substances 0.000 claims abstract description 59
- YXKMMRDKEKCERS-UHFFFAOYSA-N cyazofamid Chemical compound CN(C)S(=O)(=O)N1C(C#N)=NC(Cl)=C1C1=CC=C(C)C=C1 YXKMMRDKEKCERS-UHFFFAOYSA-N 0.000 claims abstract description 59
- 230000000694 effects Effects 0.000 claims abstract description 46
- 241000221785 Erysiphales Species 0.000 claims abstract description 45
- 240000008067 Cucumis sativus Species 0.000 claims abstract description 42
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims abstract description 39
- 239000000470 constituent Substances 0.000 claims abstract description 38
- 239000000575 pesticide Substances 0.000 claims abstract description 38
- 241000196324 Embryophyta Species 0.000 claims abstract description 29
- 206010039509 Scab Diseases 0.000 claims abstract description 29
- 241000233679 Peronosporaceae Species 0.000 claims abstract description 24
- 241000233866 Fungi Species 0.000 claims abstract description 21
- 241000219112 Cucumis Species 0.000 claims abstract description 14
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 claims abstract description 14
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 13
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 13
- 239000012752 auxiliary agent Substances 0.000 claims abstract description 11
- 241000233654 Oomycetes Species 0.000 claims abstract description 9
- 241000221198 Basidiomycota Species 0.000 claims abstract description 8
- 239000000375 suspending agent Substances 0.000 claims description 69
- 239000003795 chemical substances by application Substances 0.000 claims description 47
- 239000000839 emulsion Substances 0.000 claims description 43
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 42
- 238000000034 method Methods 0.000 claims description 22
- 239000003094 microcapsule Substances 0.000 claims description 19
- 241000209140 Triticum Species 0.000 claims description 18
- 235000021307 Triticum Nutrition 0.000 claims description 18
- 239000004615 ingredient Substances 0.000 claims description 18
- 235000002566 Capsicum Nutrition 0.000 claims description 15
- 239000006185 dispersion Substances 0.000 claims description 14
- 239000004563 wettable powder Substances 0.000 claims description 14
- 235000013399 edible fruits Nutrition 0.000 claims description 13
- 239000006002 Pepper Substances 0.000 claims description 12
- 235000016761 Piper aduncum Nutrition 0.000 claims description 12
- 235000017804 Piper guineense Nutrition 0.000 claims description 12
- 235000008184 Piper nigrum Nutrition 0.000 claims description 12
- 235000013339 cereals Nutrition 0.000 claims description 12
- 239000004562 water dispersible granule Substances 0.000 claims description 12
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 9
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 9
- 240000006365 Vitis vinifera Species 0.000 claims description 9
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 9
- 240000007594 Oryza sativa Species 0.000 claims description 7
- 235000007164 Oryza sativa Nutrition 0.000 claims description 7
- 239000004530 micro-emulsion Substances 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- 235000009566 rice Nutrition 0.000 claims description 7
- 239000007921 spray Substances 0.000 claims description 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 6
- 235000011430 Malus pumila Nutrition 0.000 claims description 6
- 235000015103 Malus silvestris Nutrition 0.000 claims description 6
- 240000008042 Zea mays Species 0.000 claims description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 6
- 239000000725 suspension Substances 0.000 claims description 6
- 241000233622 Phytophthora infestans Species 0.000 claims description 5
- 239000002689 soil Substances 0.000 claims description 5
- 235000013311 vegetables Nutrition 0.000 claims description 5
- 241000223600 Alternaria Species 0.000 claims description 4
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims description 4
- 150000003851 azoles Chemical class 0.000 claims description 4
- 235000009973 maize Nutrition 0.000 claims description 4
- 150000002825 nitriles Chemical class 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000007667 floating Methods 0.000 claims description 2
- 244000203593 Piper nigrum Species 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 26
- 230000002195 synergetic effect Effects 0.000 abstract description 20
- 244000052769 pathogen Species 0.000 abstract description 15
- 230000001717 pathogenic effect Effects 0.000 abstract description 15
- 206010059866 Drug resistance Diseases 0.000 abstract description 5
- 238000011161 development Methods 0.000 abstract description 5
- 239000000945 filler Substances 0.000 abstract description 5
- 230000001954 sterilising effect Effects 0.000 abstract description 5
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 5
- 238000001228 spectrum Methods 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 3
- 230000003111 delayed effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 description 113
- 150000001336 alkenes Chemical class 0.000 description 59
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 56
- 150000001412 amines Chemical class 0.000 description 54
- 150000002923 oximes Chemical class 0.000 description 53
- 239000002270 dispersing agent Substances 0.000 description 52
- 239000003921 oil Substances 0.000 description 43
- 235000019198 oils Nutrition 0.000 description 43
- 239000002904 solvent Substances 0.000 description 36
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 33
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 30
- 239000002994 raw material Substances 0.000 description 27
- 239000000126 substance Substances 0.000 description 27
- 239000002518 antifoaming agent Substances 0.000 description 25
- DMSMPAJRVJJAGA-UHFFFAOYSA-N benzo[d]isothiazol-3-one Chemical compound C1=CC=C2C(=O)NSC2=C1 DMSMPAJRVJJAGA-UHFFFAOYSA-N 0.000 description 25
- 229920001285 xanthan gum Polymers 0.000 description 22
- 238000009472 formulation Methods 0.000 description 21
- 210000004027 cell Anatomy 0.000 description 20
- 239000004576 sand Substances 0.000 description 20
- 230000003449 preventive effect Effects 0.000 description 19
- 239000000047 product Substances 0.000 description 19
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 18
- 238000012360 testing method Methods 0.000 description 18
- 230000003902 lesion Effects 0.000 description 17
- 239000007788 liquid Substances 0.000 description 17
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 16
- 238000011835 investigation Methods 0.000 description 16
- 229920000642 polymer Polymers 0.000 description 16
- 229940051841 polyoxyethylene ether Drugs 0.000 description 16
- 229920000056 polyoxyethylene ether Polymers 0.000 description 16
- 229920001732 Lignosulfonate Polymers 0.000 description 15
- 238000013329 compounding Methods 0.000 description 15
- 239000008367 deionised water Substances 0.000 description 15
- 229910021641 deionized water Inorganic materials 0.000 description 15
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 14
- 239000002253 acid Substances 0.000 description 14
- 238000002474 experimental method Methods 0.000 description 14
- 150000003839 salts Chemical class 0.000 description 14
- 239000000080 wetting agent Substances 0.000 description 14
- DMAXMXPDVWTIRV-UHFFFAOYSA-N 2-(2-phenylethyl)phenol Chemical compound OC1=CC=CC=C1CCC1=CC=CC=C1 DMAXMXPDVWTIRV-UHFFFAOYSA-N 0.000 description 13
- 241000894006 Bacteria Species 0.000 description 13
- 231100000419 toxicity Toxicity 0.000 description 13
- 230000001988 toxicity Effects 0.000 description 13
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid group Chemical group C(C1=CC=CC=C1)(=O)O WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 12
- 238000012545 processing Methods 0.000 description 12
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 11
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 11
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 11
- GANNOFFDYMSBSZ-UHFFFAOYSA-N [AlH3].[Mg] Chemical compound [AlH3].[Mg] GANNOFFDYMSBSZ-UHFFFAOYSA-N 0.000 description 11
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 11
- 239000000391 magnesium silicate Substances 0.000 description 11
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 11
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 10
- 240000003889 Piper guineense Species 0.000 description 10
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 10
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 10
- 235000011130 ammonium sulphate Nutrition 0.000 description 10
- 150000001450 anions Chemical class 0.000 description 10
- 238000009833 condensation Methods 0.000 description 10
- 230000005494 condensation Effects 0.000 description 10
- 230000000855 fungicidal effect Effects 0.000 description 10
- 230000002265 prevention Effects 0.000 description 10
- 239000011734 sodium Substances 0.000 description 10
- 229910052708 sodium Inorganic materials 0.000 description 10
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 10
- 235000010234 sodium benzoate Nutrition 0.000 description 10
- 239000007787 solid Substances 0.000 description 10
- 239000002562 thickening agent Substances 0.000 description 10
- 238000009736 wetting Methods 0.000 description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000004480 active ingredient Substances 0.000 description 9
- 239000000417 fungicide Substances 0.000 description 9
- 230000012010 growth Effects 0.000 description 9
- 239000003906 humectant Substances 0.000 description 9
- 231100000572 poisoning Toxicity 0.000 description 9
- 230000000607 poisoning effect Effects 0.000 description 9
- 229920002396 Polyurea Polymers 0.000 description 8
- 239000004372 Polyvinyl alcohol Substances 0.000 description 8
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 8
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 8
- 239000007864 aqueous solution Substances 0.000 description 8
- QYDYPVFESGNLHU-UHFFFAOYSA-N elaidic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCC(=O)OC QYDYPVFESGNLHU-UHFFFAOYSA-N 0.000 description 8
- QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 description 8
- 229940073769 methyl oleate Drugs 0.000 description 8
- 229920005646 polycarboxylate Polymers 0.000 description 8
- 229920002451 polyvinyl alcohol Polymers 0.000 description 8
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 8
- 159000000000 sodium salts Chemical class 0.000 description 8
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 8
- 241000198596 Alternaria tomatophila Species 0.000 description 7
- 229920002261 Corn starch Polymers 0.000 description 7
- 229910019142 PO4 Inorganic materials 0.000 description 7
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 7
- 239000003899 bactericide agent Substances 0.000 description 7
- 239000008120 corn starch Substances 0.000 description 7
- 229940099112 cornstarch Drugs 0.000 description 7
- 239000002736 nonionic surfactant Substances 0.000 description 7
- 239000010452 phosphate Substances 0.000 description 7
- 239000002574 poison Substances 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 238000010008 shearing Methods 0.000 description 7
- 229910052710 silicon Inorganic materials 0.000 description 7
- 239000010703 silicon Substances 0.000 description 7
- 239000005711 Benzoic acid Substances 0.000 description 6
- 241000222201 Colletotrichum capsici Species 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000002671 adjuvant Substances 0.000 description 6
- 125000000129 anionic group Chemical group 0.000 description 6
- 235000012216 bentonite Nutrition 0.000 description 6
- 235000010233 benzoic acid Nutrition 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 6
- 235000019441 ethanol Nutrition 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 150000003871 sulfonates Chemical class 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 239000004927 clay Substances 0.000 description 5
- 238000000205 computational method Methods 0.000 description 5
- 230000001276 controlling effect Effects 0.000 description 5
- 239000002552 dosage form Substances 0.000 description 5
- 230000000857 drug effect Effects 0.000 description 5
- 238000011081 inoculation Methods 0.000 description 5
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 5
- 239000003755 preservative agent Substances 0.000 description 5
- 230000002335 preservative effect Effects 0.000 description 5
- PYSRRFNXTXNWCD-UHFFFAOYSA-N 3-(2-phenylethenyl)furan-2,5-dione Chemical compound O=C1OC(=O)C(C=CC=2C=CC=CC=2)=C1 PYSRRFNXTXNWCD-UHFFFAOYSA-N 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 241000223195 Fusarium graminearum Species 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 229920000147 Styrene maleic anhydride Polymers 0.000 description 4
- 229920001807 Urea-formaldehyde Polymers 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 230000002528 anti-freeze Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 4
- 238000004364 calculation method Methods 0.000 description 4
- 239000004202 carbamide Substances 0.000 description 4
- 239000007859 condensation product Substances 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 239000003337 fertilizer Substances 0.000 description 4
- 239000003112 inhibitor Substances 0.000 description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- 239000006210 lotion Substances 0.000 description 4
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 4
- ODGAOXROABLFNM-UHFFFAOYSA-N polynoxylin Chemical compound O=C.NC(N)=O ODGAOXROABLFNM-UHFFFAOYSA-N 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 230000001018 virulence Effects 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 239000005995 Aluminium silicate Substances 0.000 description 3
- 240000008574 Capsicum frutescens Species 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 150000008051 alkyl sulfates Chemical class 0.000 description 3
- 235000012211 aluminium silicate Nutrition 0.000 description 3
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 150000008378 aryl ethers Chemical class 0.000 description 3
- 229960000892 attapulgite Drugs 0.000 description 3
- 239000000440 bentonite Substances 0.000 description 3
- 229910000278 bentonite Inorganic materials 0.000 description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 description 3
- 239000001390 capsicum minimum Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical class O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 3
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 3
- 150000002191 fatty alcohols Chemical class 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 239000004519 grease Substances 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 230000010534 mechanism of action Effects 0.000 description 3
- 229920000609 methyl cellulose Polymers 0.000 description 3
- 239000001923 methylcellulose Substances 0.000 description 3
- 235000010981 methylcellulose Nutrition 0.000 description 3
- 239000002480 mineral oil Substances 0.000 description 3
- 235000010446 mineral oil Nutrition 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 229910052625 palygorskite Inorganic materials 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 description 2
- RQDJADAKIFFEKQ-UHFFFAOYSA-N 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile Chemical compound C1=CC(Cl)=CC=C1CCC(C=1C=CC=CC=1)(C#N)CN1N=CN=C1 RQDJADAKIFFEKQ-UHFFFAOYSA-N 0.000 description 2
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical class C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 description 2
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
- 235000016068 Berberis vulgaris Nutrition 0.000 description 2
- 241000335053 Beta vulgaris Species 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- 240000008790 Musa x paradisiaca Species 0.000 description 2
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical class CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 241001674391 Sphaerulina musiva Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical compound OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 241000607479 Yersinia pestis Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 229910021536 Zeolite Inorganic materials 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000013019 agitation Methods 0.000 description 2
- 150000001335 aliphatic alkanes Chemical class 0.000 description 2
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 2
- 150000008055 alkyl aryl sulfonates Chemical class 0.000 description 2
- 150000008052 alkyl sulfonates Chemical class 0.000 description 2
- 239000007900 aqueous suspension Substances 0.000 description 2
- 125000005228 aryl sulfonate group Chemical group 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000005018 casein Substances 0.000 description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
- 235000021240 caseins Nutrition 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical class ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 230000017858 demethylation Effects 0.000 description 2
- 238000010520 demethylation reaction Methods 0.000 description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 2
- 239000007884 disintegrant Substances 0.000 description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- RBWGTZRSEOIHFD-UHUFKFKFSA-N fenaminstrobin Chemical compound CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(/C)\C=C\C1=C(Cl)C=CC=C1Cl RBWGTZRSEOIHFD-UHUFKFKFSA-N 0.000 description 2
- 239000010419 fine particle Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 229920000159 gelatin Polymers 0.000 description 2
- 239000008273 gelatin Substances 0.000 description 2
- 235000019322 gelatine Nutrition 0.000 description 2
- 235000011852 gelatine desserts Nutrition 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- ILHIHKRJJMKBEE-UHFFFAOYSA-N hydroperoxyethane Chemical compound CCOO ILHIHKRJJMKBEE-UHFFFAOYSA-N 0.000 description 2
- 230000002262 irrigation Effects 0.000 description 2
- 238000003973 irrigation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000002438 mitochondrial effect Effects 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- PSZYNBSKGUBXEH-UHFFFAOYSA-M naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)[O-])=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-M 0.000 description 2
- 150000002903 organophosphorus compounds Chemical class 0.000 description 2
- 239000003090 pesticide formulation Substances 0.000 description 2
- UZRCGISJYYLJMA-UHFFFAOYSA-N phenol;styrene Chemical compound OC1=CC=CC=C1.C=CC1=CC=CC=C1 UZRCGISJYYLJMA-UHFFFAOYSA-N 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 238000004382 potting Methods 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- ARENMZZMCSLORU-UHFFFAOYSA-N propan-2-yl naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)OC(C)C)=CC=CC2=C1 ARENMZZMCSLORU-UHFFFAOYSA-N 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000012453 solvate Substances 0.000 description 2
- 238000009331 sowing Methods 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 description 2
- 229940124530 sulfonamide Drugs 0.000 description 2
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 2
- 150000003852 triazoles Chemical class 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 2
- 239000010457 zeolite Substances 0.000 description 2
- KTVWCJUQJUOBOF-UHFFFAOYSA-N (2-ethenylphenyl) dihydrogen phosphate Chemical compound OP(O)(=O)OC1=CC=CC=C1C=C KTVWCJUQJUOBOF-UHFFFAOYSA-N 0.000 description 1
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
- CSNIZNHTOVFARY-UHFFFAOYSA-N 1,2-benzothiazole Chemical class C1=CC=C2C=NSC2=C1 CSNIZNHTOVFARY-UHFFFAOYSA-N 0.000 description 1
- IRUIHTBQNFOVFQ-UHFFFAOYSA-N 1,2-diphenylethenylbenzene phenyl dihydrogen phosphate Chemical compound P(=O)(O)(O)OC1=CC=CC=C1.C1(=CC=CC=C1)C=C(C1=CC=CC=C1)C1=CC=CC=C1 IRUIHTBQNFOVFQ-UHFFFAOYSA-N 0.000 description 1
- ZPQOPVIELGIULI-UHFFFAOYSA-N 1,3-dichlorobenzene Chemical class ClC1=CC=CC(Cl)=C1 ZPQOPVIELGIULI-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 125000004201 2,4-dichlorophenyl group Chemical group [H]C1=C([H])C(*)=C(Cl)C([H])=C1Cl 0.000 description 1
- HXVNBWAKAOHACI-UHFFFAOYSA-N 2,4-dimethyl-3-pentanone Chemical compound CC(C)C(=O)C(C)C HXVNBWAKAOHACI-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- QHNDFWPCDITBSG-UHFFFAOYSA-N 2-(4-methylphenyl)-1h-imidazole Chemical class C1=CC(C)=CC=C1C1=NC=CN1 QHNDFWPCDITBSG-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- YNNUSGIPVFPVBX-UHFFFAOYSA-N 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine Chemical compound CN1CCCC1CCOC(C)(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 YNNUSGIPVFPVBX-UHFFFAOYSA-N 0.000 description 1
- CFWRDBDJAOHXSH-SECBINFHSA-N 2-azaniumylethyl [(2r)-2,3-diacetyloxypropyl] phosphate Chemical compound CC(=O)OC[C@@H](OC(C)=O)COP(O)(=O)OCCN CFWRDBDJAOHXSH-SECBINFHSA-N 0.000 description 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 1
- 239000004254 Ammonium phosphate Substances 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 241000123650 Botrytis cinerea Species 0.000 description 1
- 241000219198 Brassica Species 0.000 description 1
- 235000011331 Brassica Nutrition 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 1
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 1
- 241000499436 Brassica rapa subsp. pekinensis Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 240000008384 Capsicum annuum var. annuum Species 0.000 description 1
- 235000002568 Capsicum frutescens Nutrition 0.000 description 1
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
- 102100025287 Cytochrome b Human genes 0.000 description 1
- 108010075028 Cytochromes b Proteins 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 239000005775 Fenbuconazole Substances 0.000 description 1
- 241000223218 Fusarium Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 241000555709 Guignardia Species 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 241000220225 Malus Species 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 240000001910 Momordica cochinchinensis Species 0.000 description 1
- 235000009812 Momordica cochinchinensis Nutrition 0.000 description 1
- 241001363490 Monilia Species 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 241000228143 Penicillium Species 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241000255964 Pieridae Species 0.000 description 1
- 241001503464 Plasmodiophora Species 0.000 description 1
- 241001503460 Plasmodiophorida Species 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241001281805 Pseudoperonospora cubensis Species 0.000 description 1
- 241000221300 Puccinia Species 0.000 description 1
- 241000233639 Pythium Species 0.000 description 1
- 239000004113 Sepiolite Substances 0.000 description 1
- 241001533598 Septoria Species 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 235000009818 Trichosanthes kirilowii Nutrition 0.000 description 1
- 241000228452 Venturia inaequalis Species 0.000 description 1
- ZRXADTFMGYNRKV-UHFFFAOYSA-N [S].C1=CC=CC2=CC=CC=C21 Chemical compound [S].C1=CC=CC2=CC=CC=C21 ZRXADTFMGYNRKV-UHFFFAOYSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 229910000148 ammonium phosphate Inorganic materials 0.000 description 1
- 235000019289 ammonium phosphates Nutrition 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- 208000020282 anthrax disease Diseases 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 210000003323 beak Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- REEJOFMTJPOBAY-UHFFFAOYSA-N benzene;1h-pyrrole Chemical class C=1C=CNC=1.C1=CC=CC=C1 REEJOFMTJPOBAY-UHFFFAOYSA-N 0.000 description 1
- 150000004054 benzoquinones Chemical class 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 238000012661 block copolymerization Methods 0.000 description 1
- JIJAYWGYIDJVJI-UHFFFAOYSA-N butyl naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S(=O)(=O)OCCCC)=CC=CC2=C1 JIJAYWGYIDJVJI-UHFFFAOYSA-N 0.000 description 1
- KVNRLNFWIYMESJ-UHFFFAOYSA-N butyronitrile Chemical compound CCCC#N KVNRLNFWIYMESJ-UHFFFAOYSA-N 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 235000012241 calcium silicate Nutrition 0.000 description 1
- 235000013877 carbamide Nutrition 0.000 description 1
- 239000006013 carbendazim Substances 0.000 description 1
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 229920003064 carboxyethyl cellulose Polymers 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 238000005660 chlorination reaction Methods 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 244000038559 crop plants Species 0.000 description 1
- XCIXKGXIYUWCLL-UHFFFAOYSA-N cyclopentanol Chemical compound OC1CCCC1 XCIXKGXIYUWCLL-UHFFFAOYSA-N 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 150000002012 dioxanes Chemical class 0.000 description 1
- JMGZBMRVDHKMKB-UHFFFAOYSA-L disodium;2-sulfobutanedioate Chemical compound [Na+].[Na+].OS(=O)(=O)C(C([O-])=O)CC([O-])=O JMGZBMRVDHKMKB-UHFFFAOYSA-L 0.000 description 1
- 235000021038 drupes Nutrition 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 230000008686 ergosterol biosynthesis Effects 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 235000012055 fruits and vegetables Nutrition 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 210000004602 germ cell Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 229940095686 granule product Drugs 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 150000002460 imidazoles Chemical class 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000003350 kerosene Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical compound C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 1
- 229940042880 natural phospholipid Drugs 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- WHHIPMZEDGBUCC-UHFFFAOYSA-N probenazole Chemical compound C1=CC=C2C(OCC=C)=NS(=O)(=O)C2=C1 WHHIPMZEDGBUCC-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000007065 protein hydrolysis Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 235000019355 sepiolite Nutrition 0.000 description 1
- 229910052624 sepiolite Inorganic materials 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 239000013008 thixotropic agent Substances 0.000 description 1
- 238000003971 tillage Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000012876 topography Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to pesticide fields, and in particular to a kind of composition pesticide and its application.The composition is made of active constituent, filler and auxiliary agent.Wherein active components A is alkene oxime amine, and active constituent B is one or more in benzoxazole, imazalil, cyazofamid, metconazole.The composition by sac fungus, basidiomycetes, Fungi Imperfecti and the fungus-caused plurality of plant diseases of Oomycete class to having good control effect, cucumber downy mildew, powdery mildew, anthracnose, scab can effectively be prevented, tomato late blight, leaf mold, early blight, gray mold, the generation and harm of the plant diseases such as western melon powdery mildew, anthracnose, blight dis-ease, droop.The composition wide sterilization spectrum has apparent synergistic effect, can reduce dosage, reduces drug cost, and germ is delayed to generate and develop the resistance of single medicine, thus can effectively delay the occurrence and development of pathogen drug resistance.
Description
Technical field
The invention belongs to pesticide fields.Be related to a kind of bactericidal composition and its application, and in particular to one kind containing it is active at
The composition of point A alkene oxime amines and active constituent B (one or more in benzoxazole, imazalil, cyazofamid, metconazole) and its
Using.
Background technology
Crop-planting is given every year by sac fungus, basidiomycetes, Fungi Imperfecti and the fungus-caused plurality of plant diseases of Oomycete class
Different degrees of loss is caused with production.Sac fungus, basidiomycetes, oomycetes and the fungus-caused plant disease of Fungi Imperfecti include Huang
Melon downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, charcoal
Subcutaneous ulcer disease, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape, white rot, gray mold, apple spot fallen leaves
Disease, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat
Head blight, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, head smut, the late blight of potato, early blight
Deng.
It is the most effective means of controlling plant diseases using chemical agent.Methoxy acrylic bactericide and azoles
Series bactericidal agent is the mainstream fungicide of controlling plant diseases, but applies single chemical bactericide to continuous high dose for a long time, is held
The problems such as easily causing residual, environmental pollution and the pathogen drug resistance of medicament.
Rational chemical bactericide combination or mixture, which has, expands fungicidal spectrum, improves control effect, extends the optimum period for applying fertilizer, subtracts
Few dosage reduces poisoning, reduces residual, delaying the effects that generation and development of pathogen drug resistance, and bactericide compounded is solution
Certainly one of the maximally efficient method of the above problem.Develop new product fungicide price is constantly soaring, and in contrast, it studies and opens
Hair efficiently, the compounding of low toxicity, low-residual have that small investment, the lead time is short and is paid attention to both at home and abroad, it is numerous and confused increase to develop grinds
Dynamics processed.We based on the indoor screening and field trials, specify alkene oxime amine and benzoxazole, imazalil, cyazofamid or
Metconazole is compounded, and has apparent synergistic effect.
And so far, there are no documents to disclose alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole sterilization group
Object is closed, and by the composition of gained for preventing agricultural disease.
Invention summary
Present invention aims at by alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole rational mixture, obtain
Bactericidal composition, for preventing agricultural disease.The composition can improve control effect, delay pathogen development of drug resistance, subtract
Few peasant's drug cost.
The present composition also with that can improve crop growth, development, makes crop generate positive physiological effect
Effect, including improve crop quality, improve yield and crop commodity rate etc..
The present composition has following remarkable result and advantage：Active components A is alkene oxime amine, and active constituent B is selected from nitrile
One or more in benzene azoles, imazalil, cyazofamid, metconazole, active constituent B preferably is selected from one kind in metconazole, benzoxazole
Or it is a variety of.Active components A is mitochondrial respiratory inhibitor, inhibits the electron transmission of mitochondria, active constituent B that can then inhibit disease
The biosynthesis of bacterium cell important component, so as to cause germ cell death.Active components A and active constituent B both tool
There is different mechanism of action, cross resistance is not present, can be synergistic, it reduces and single dose is used alone.
It is killed made of being compounded with benzoxazole, imazalil, cyazofamid or metconazole by alkene oxime amine the present invention provides one kind
Bacteria composition.The present invention also provides the formula indoor screening test experiment of different component formula, field control effectiveness tests.
According to the one side of the application, this application provides a kind of composition pesticide, the composition pesticide contains two
Kind active component：Active components A is alkene oxime amine, and active constituent B is in benzoxazole, imazalil, cyazofamid or metconazole
It is one or more.
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:80~
80:1。
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:60~
60:1。
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:20~
20:1。
According to the certain embodiments of the application, it is total that the weight summation of the active component of the composition pesticide accounts for composition
The 5%~81% of weight.
According to the certain embodiments of the application, it is total that the weight summation of the active component of the composition pesticide accounts for composition
The 10~61% of weight.
(solid or liquid well known to those skilled in the art may be used in the preparation of the composition finished product preparation of the present invention
Body) carrier and various auxiliary agents.
According to the certain embodiments of the application, the composition pesticide can be prepared into suitable agriculture by common processing method
A kind of dosage form that industry uses.After active component is mixed with liquid-carrier (solvent) or solid carrier, it is added one or more of
Surfactant such as emulsifier, dispersant, wetting agent, adhesive, stabilizer and antifoaming agent etc..Containing at least in usual composition
A kind of carrier and at least one surfactant.In all cases, it should be ensured that present composition active component is uniformly distributed.
According to the certain embodiments of the application, the present composition can be prepared into suitable agricultural use by known method
A kind of dosage form, relatively good dosage form has aqueous suspension agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, outstanding
Floating seed coat agent, water dispersible granules, seed treatment dispersible pulvis, seed treatment microcapsule suspending agent or missible oil etc..
According to the certain embodiments of the application, the composition pesticide is at foliar spray, seed treatment or soil
Reason.
According to the property of these compositions and application composition institute's purpose to be achieved and ambient conditions, can select by
Composition to spray, impregnate, atomizing, broadcast sowing, pour, the application of the method for pouring root or the like.
According to the one side of the application, this application provides the use that the composition pesticide is used for controlling plant diseases
On the way.
According to the certain embodiments of the application, the plant disease is by sac fungus, basidiomycetes, oomycetes and Fungi Imperfecti
Fungi causes.
According to the certain embodiments of the application, the plant disease is cucumber downy mildew, powdery mildew, anthracnose, black star
Disease, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, blight dis-ease, droop, downy mildew of garpe, anthrax
Disease, powdery mildew, anthrachose of grape, white rot, gray mold, alternaria leaf spot of apple, scab, ring spot, anthracnose, melon and capsicum
Anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, corn
Banded sclerotial blight, head smut, the late blight of potato, early blight etc..
According to the one side of the application, this application provides a kind of method of controlling plant diseases, the method is by institute
It states composition and is applied to Cereal, fruit tree, vegetables and industrial crops or its planting area, with controlling plant diseases.
According to the certain embodiments of the application, the plant disease is by sac fungus, basidiomycetes, oomycetes and Fungi Imperfecti
Fungi causes.
According to the certain embodiments of the application, the plant disease is cucumber downy mildew, powdery mildew, anthracnose, black star
Disease, tomato late blight, leaf mold, early blight, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, grape downy mildew
Disease, anthracnose, powdery mildew, anthrachose of grape, white rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, charcoal
Subcutaneous ulcer disease, melon and pepper anthracnose, epidemic disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice line
Blight, bakanae disease, maize sheath blight, head smut, the late blight of potato, early blight etc..
According to the certain embodiments of the application, the component of the composition pesticide is configured to preparation application or bucket is mixed and applied
With.
According to the one side of the application, this application provides a kind of method preparing the composition pesticide, the sides
Method is by the active components A, active constituent B and agriculturally acceptable carrier or auxiliary agent mix.
Detailed description of the invention
Definition
Alkene oxime amine (Fenaminstrobin) chemical name：N- methyl -2- [2- ((((1- methyl -3- (2,6- dichloro-benzenes
Base) -2- acrylic) amino) oxygroup) methyl) phenyl] -2- methoxyimino acetic amides, CAS registration numbers：366815-39-6.
Have the following structure formula：
Alkene oxime amine wide sterilization spectrum, activity are high, have prevention and therapeutic effect and have with environmental organism good compatible
Property.It is good to being had by the fungus-caused plurality of plant diseases such as mastigomycetes, zygomycete, sac fungus, basidiomycetes and Fungi Imperfecti
Preventive effect.Preferable preventive and therapeutic effect can be all had to multiple diseases, especially to white powder on the crops such as cereal, fruit tree, vegetables
Disease, rust, leaf spot preventive effect are notable.
Benzoxazole (Fenbuconazole) chemical name：4- (4- chlorphenyls) -2- phenyl -2 (1H-1,2,4- triazoles -1-
Ylmethyl) butyronitrile, CAS registration numbers:114369-43-6.Have the following structure formula：
Benzoxazole is called azoles bacterium nitrile, benzene cyanogen azoles, is triazole type systemic fungicide, and sterol demethylation inhibitors can prevent
The germ spore intrusion crop plant tissue to have germinateed, inhibits the growth of mycelia.It is used in germ incubation period, the hair of germ can be prevented
It educates；It is used after the onset, next-generation spore can be made to deform, lose infection ability, there is prevention effect and therapeutic effect to disease.
To the Septoria of cereal crop, Puccinia and rye beak spore, the beet on beet gives birth to tail spore, the Botrytis cinerea on grape
Belong to, grape Guignardia and grape snag shell, the Monilia on drupe, such as venturia inaequalis and to crop field work on fruit tree
Object, rice, banana, vegetables and many diseases of garden crop are effective.
Imazalil (Imazalil) chemical name：(±) allyl 1- (2,4- dichlorophenyl) -2- imidazoles -1- base ethyls
Ether, CAS registration numbers:35554-44-0.Have the following structure formula：
Imazalil is called enzyme, for preventing the crop diseases such as citrus, mango, banana, apple, melon, it can also be used to
Cereal crops disease is prevented, has special efficacy to the penicillium of resisting carbendazim, probenazole.Also have to fruits and vegetables powdery mildew, anthracnose good
Good preventive effect.
Cyazofamid (Cyazofamid) chemical name：Chloro- 2- cyano-N, N- dimethyl -5- the p-methylphenyl imidazoles -1- sulphurs of 4-
Amide, CAS registration numbers:120116-88-3.Have the following structure formula：
Cyazofamid is sulfanilamide (SN) imidazoles protective fungicide, is had to downy mildew, epidemic disease, late blight, clubroot, samping off etc.
Special efficacy.Mechanism of action is that the electron transmission of mitochondrial cytochrome b c1 complexs in Oomycete germ body is blocked to carry out interfering energy
Supply, binding site is the centers Q of enzyme, referred to as QiI (inhibitor, Quinone inside inside benzoquinones
Inhibitors) series bactericidal agent, with other fungicide without cross tolerance.It may be due to target to the high selection activity of pathogen
Enzyme is marked caused by the sensitivity difference of medicament.To Oomycete fungal such as downy mildew, Pseudo peronospara, phytophthora, pythium spp with
And the plasmodiophora brassica bacteria of Plasmodiophoromycetes has very high bioactivity.
Metconazole (Metconazole) chemical name：5- (4- chlorphenyls) -2,2- dimethyl -1- (1H-1,2,4- triazoles -
1- ylmethyls) cyclopentanol, molecular formula C17H22ClN3O, CAS registration number：125116-23-6.Structural formula is as follows：
Metconazole by Japanese Wu Yu chemical industrial companies and american cyanamide (being now BASF) joint development, to wheat, corn,
Many diseases that leaf, the fringe of rapeseed, soybean, lawn, fruit tree etc. occur have very high preventive effect, are mainly used for cereal crops
Prevent disease caused by head blight, short shape rust, leaf rust, yellow rust, crown rust, powdery mildew, glume blight and septoria musiva etc..
For C-14 demethylation enzyme inhibitors in ergosterol biosynthesis.Although the mechanism of action as other triazole bactericidal agents,
But then difference is larger for activity profile.Two kinds of isomers have bactericidal activity, but Cis activity is higher than trans-.The antifungal spectrum of metconazole
Widely, and activity is splendid.Metconazole field is applied has remarkable effect to cereal crops septoria musiva, fusarium and handle rest fungus plant disease
Fruit.For metconazole compared with traditional biocide agent, dosage is extremely low and prevents cereal and plants sick range very extensively.
Term " composition pesticide " indicate one or more active constituents containing antimicrobial effective amount or its agriculturally
Acceptable tautomer, solvate, hydrate or salt, with other auxiliary agents, the mixture of carrier.By the active constituent
The purpose for being prepared into bactericidal composition is in order to more easily to agricultural irrigation dispenser.In the application, " composition pesticide " is also referred to as
For " bactericidal composition ".
Term " active constituent ", also known as " active ingredient ", " active component " refer to and play sterilization work in the bactericidal composition
Key active ingredients or its agriculturally acceptable tautomer, solvate, hydrate or salt.In certain of the application
In a little embodiments, the active constituent of the bactericidal composition includes A alkene oxime amines.In the certain embodiments of the application,
The active constituent B (one kind in benzoxazole, imazalil, cyazofamid and metconazole) of the bactericidal composition.In the application
Certain embodiments in, the active constituent of the bactericidal composition includes A and B.In the certain embodiments of the application, institute
The active constituent for stating bactericidal composition is made of A and B.
Term " auxiliary agent ", also known as " adjuvant " are Pesticide formulations or in use, are used to improve medicament physicochemical property
Auxiliary substance.Including wetting agent, emulsifier, solvent, dispersant, sticker, stabilizer, synergist, safener, bleeding agent
Deng.Such as in agriculture breast 1601#, alkylaryl sulfonates, lignosulfonates, lactic casein, mineral oil, gelatin, polyvinyl alcohol etc.
It is one or more.
Term " carrier " refer to can it is combined with active constituent or combine with make it easier for being administered to object (such as plant,
Crop or careless class) natural or synthetic organic or inorganic compound.Therefore, the carrier is preferably inert, at least should be
Agricultural is acceptable.The carrier can be solid or liquid.
The carrier that can be used in the present invention can be used as solid carrier either solid can also be liquid
Have for example：Phyteral powdery type (such as soy meal, starch, grain dust, wood powder, bark powder, sawdust, walnut shell powder, wheat bran,
The particle of cellulose powder, coconut husk, corncob and tobacco stem extracts the residue etc. after plant essence), paper, sawdust, crush
The synthesized polymer body of synthetic resin etc., clay class (such as kaolin, bentonite, acid china clay, attapulgite etc.), talcum powder class.
Silica (such as diatomite, silica sand, mica, aqueous silicic acid, calcium silicates), activated carbon, natural mineral matter class (float stone, green slope thread
Stone and zeolite etc.), fire diatomite, sand, (such as polyethylene, polypropylene, polyvinylidene chloride etc.), the chlorination such as plastics medium
Chemical fertilizer, the soil of the inorganic mineral powder of potassium, calcium carbonate, calcium phosphate etc., ammonium sulfate, ammonium phosphate, urea, ammonium chloride etc.
Fertilizer and white carbon, zeolite powder, the wooden chaff, paraffin, methylcellulose, carboxymethyl cellulose and carboxyethyl cellulose etc., these objects
Matter can be used alone or two or more is mixed.
What can be used as liquid-carrier can select in llowing group of materials, such as water, alcohols (such as methanol, ethyl alcohol,
Isopropanol, butanol, ethylene glycol etc.), ketone (such as acetone, methyl ethyl ketone, isobutyrone, cyclohexanone etc.), ethers (example
Such as ether, dioxanes, methylcellulose, tetrahydrofuran), aliphatic hydrocarbon class (such as kerosene, mineral oil etc.), virtue
Fragrant race's hydrocarbon (such as benzene,toluene,xylene, solvent naphtha, alkylnaphthalene, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbon, chlorobenzene,
Deng), halogenated hydrocarbon class, amides, sulfone class, dimethyl sulfoxide (DMSO), mineral and vegetable oil, animal oil, agriculture breast 1601#, alkane
Base arylsulphonate, lignosulfonates, lactic casein, gelatin, polyvinyl alcohol etc..
As other adjuvants can according to use purpose select to use, also can be used alone, certain occasions two or more
Adjuvant shares or certain occasions can not use adjuvant completely.For make active ingredient compound emulsification, dispersion, it is solubilized,
And/or wetting can use surfactant that can for example enumerate fatty alcohol polyoxyethylene ether, polyxyethylated aryl
Ether, polyoxyethylene higher fatty acid esters, polyoxyethylene alcohol or the phosphate of phenol, the aliphatic ester of polyalcohol, alkane aromatic sulfonic acid, naphthalene sulphur
Branch dress copolymer, butyl naphthalene sulfonate, alkylaryl sulfonates, the alkyl of acid polymer, lignosulfonates, macromolecule comb shape
The polyacrylates such as sodium sulfosuccinate, grease, fatty alcohol and ethylene oxide condensate, alkyltaurate, protein hydrolysis
Object.Suitable oligosaccharide object or polymer, for example, based on individual vinyl monomer, acrylic acid, EO and/or PO or its with for example
The combination of (polynary) alcohol or (polynary) amine.
To make active ingredient dispersion stability, attachment and/or combination, such as xanthans, aluminium-magnesium silicate, bright can be used
Glue, starch, methyl cellulose, polyvinyl alcohol, polyvinyl acetate and natural phospholipid (such as cephalin and lecithin) and synthesis
The adjuvants such as phosphatide, bentonite, sodium lignin sulfonate.
The wherein optional spent glycol of antifreezing agent, propylene glycol, glycerine, sorbierite.Deflocculant as suspension product
The adjuvant such as naphthalene sulfonic acid polymer, polymeric phosphate can be used.
Organic silicon defoamer can be used in antifoaming agent.
Optionally, also may include other annexing ingredients, for example, protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent,
Stabilizer, screening agent.
Herein described bactericidal composition contains active components A and active constituent B, has apparent synergistic effect.This Shen
Please term " synergistic effect " used, also known as " act synergistically ", referring to different chemical substances has when being used in combination and cooperate
Effect, the effect with obvious effects higher than each separate constituent of generation.
According to the certain embodiments of the application, the control effect of the bactericidal composition is than any one separate constituent
Control effect is higher by 10% or more, for example, be higher by 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%,
19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%,
34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%,
49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%,
64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%,
79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%,
94%, 95%, 96%, 97%, 98%, 99% or more or it is higher by 100%.
According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 1:80~
80:1, such as 1:80~75:1、1:80~60:1、1:80~40:1、1:80~10:1、1:60~5:1、1:40~3:1、1:20
~2:1、1:20~20:1、1:20~40:1、1:20~60:1；Preferably 1:60~60:1, such as 1:55~55:1、1:40~
40:1、1:30~30:1、1:20~20:1、1:10~10:1、1:5~5:1；More excellent is 1:20~20:1, such as 1:18~18:
1、1:15~15:1、1:10~10:1、1:5~5:1、1:5~1:1、1:4~1:1、1:3~1:1、1:2~1:1、4:1~15:
1.According to the certain embodiments of the application, the weight part ratio of the active components A and active constituent B are 80:1、60:1、
40:1、20:1、10:1、5:1、3:1、1:1、1:3、1:5、1:10、1:20、1:40、1:60、1:80。
According to the certain embodiments of the application, in one embodiment, the active component of the composition pesticide
Weight summation accounts for the 5%~81% of composition gross weight, for example, 5%~70%, 5%~60%, 5%~50%, 5%~40%,
5%~30%, 5%~20%, 5%~10%, 10%~81%, 10%~70%, 20%~81%, 20%~70%,
30%~81%, 30%~70%, 40%~81%, 40%~70%, 50%~81%, 50%~70% or 60%~
81%；Preferably 10~61%, such as 10~50%, 10~40%, 10~30%, 10~20%, 20~61%, 20~
50%, 20~40%, 20~30%, 30~61%, 30~50%, 30~40%, 40~61%, 40~50% or 50~
61%.According to the certain embodiments of the application, the weight summation of the alkene oxime amine and azoles fungicide accounts for the sterilization group
Close object gross weight 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%,
19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%,
34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%,
49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%,
64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%,
79%, 80% or 81%.
" insecticide-applying way " includes but not limited to known in the art of foliar spray, soil treatment, seed treatment etc.
What application method.Herein described active constituent or bactericidal composition can be given at any time.Such as the active constituent
Or bactericidal composition can be used before agricultural pest generation, when occurring or after occurring, such as can be occurred in pest and disease damage
It is preceding or occur after about 1 hour, about 2 hours, about 4 hours, about 5 hours, about 8 hours, about 12 hours, about 24 hours, about 2 days,
About 4 days, about 8 days, about 16 days, about 30 days or 1 month, dispenser in about 2 months.
Herein described bactericidal composition can also be used for multiple times with first use.When used multiple times the notch, can with
Every the mode dispenser of random time, for example, be divided between subsequent dose and preceding dosage about 8 weeks, about 4 weeks, about 2 weeks, about 1 week, about
5 days, about 3 days, about 2 days, about 24 hours, about 12 hours, about 8 hours, about 6 hours, about 4 hours, about 3 hours, about 2 hours, about 1
Hour, about 30 minutes or less time.
Herein described bactericidal composition can be used alone, and can also be used in mixed way with other suitable fungicide.Institute
State be used in mixed way can be used simultaneously with other fungicide or successively use.When in use, can be arbitrary with interval when priority
Between mode use.
The present composition can be prepared into the various dosage forms of suitable agricultural use by known method, and relatively good dosage form has
Aqueous suspension agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, suspension seed-coating agent, water dispersible granules, at seed
Manage dispersible pulvis, seed treatment microcapsule suspending agent or missible oil etc..
The present invention composition prepare when, can according to method known in those skilled in the art (such as《Pesticide
Formulation technology》, Liu Bulin chief editors, the preparation processing method involved in the second edition is hereby incorporated by reference).
When composition pesticide of the present invention is configured to suspending agent, auxiliary agent includes：Dispersant, thickener, is prevented wetting agent
Rotten agent, antifoaming agent, antifreezing agent and/or water etc..Wherein：Dispersant is selected from polycarboxylate salt dispersant, rosin dispersant, phosphate
Class dispersant, macromolecule emulsion dispersant, alkyl naphthalene sulfonic acid condensation polymer sodium salt, alkylnaphthalene sulfonate condensation polymer, ethyoxyl triphen
Vinylphenol phosphate, organophosphorus compounds, combed high-molecular copolymer, polyoxyethylene aryl ether, polyoxyethylene aryl phenyl ether
It is one or more in phosphate amine salt and styrene phenol polyoxyethylene anionic dispersing agents etc.；The dosage of the dispersant is
The 1-8% of total formulation weight, such as 2-7%, preferably 3-6%, such as 3-5%, 4-5% or 4-6%；Wetting agent is selected from alkyl phenol
The poly- base ether formaldehyde condensation products sulfate of polyoxyethylene, aryl sulfonate formaldehyde condensates, alkylnaphthalene sulfonate and anion soak
Agent composition, isopropyl naphthalene sulfonate, normal-butyl naphthalene sulfonate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyoxy
Vinyl ethers phosphate, alkyl sulfate, sulfosuccinate, ethoxy alcohol, block copolymer, polyxyethylated alcohol and fat
It is one or more in alcohol polyoxyethylene ether etc.；The dosage of the wetting agent be total formulation weight 1-6%, such as 2-5% or
3-4%, preferably 2-4%, such as 2-3% or 3-4%；The one kind of thickener in xanthans, aluminium-magnesium silicate and bentonite etc.
Or it is a variety of；The dosage of the thickener is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-
6%, preferably 1-5%, such as 2-4% or 1-3%；Preservative is selected from benzoic acid, sodium benzoate and BIT (1,2- benzisothiazoles
Quinoline -3- ketone) etc. in it is one or more；The dosage of the preservative be total formulation weight 0.1-10%, such as 1-9%,
0.1-5%, 0.5-5% or 1-5%, preferably 0.2-2%, such as 0.5-1% or 1-2%；Antifoaming agent is organic silicon antifoaming agent
Deng；The dosage of the antifoaming agent is the 0.1-10% of total formulation weight, such as 1-9%, 0.1-5%, 0.5-5% or 1-5% are excellent
Select 0.4-1.0%, such as 0.6-0.8%；Antifreezing agent is selected from ethylene glycol, propylene glycol, glycerine, urea and inorganic salts such as sodium chloride
It is one or more in；The dosage of the antifreezing agent is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-
8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4% or 1-3%；And surplus is water.By pesticide combination of the present invention
When object is configured to wettable powder, the auxiliary agent includes：Dispersant, wetting agent and/or filler etc..Wherein：Dispersant is selected from
It is one or more in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate and alkylnaphthalene sulfonate formaldehyde condensation products etc.；Institute
The dosage for stating dispersant is the 1-10% of total formulation weight, such as 2-9%, 3-8% or 4-7%, preferably 3-7%, such as 4-6%
Or 5-6%；Wetting agent is one or more in alkyl sulfate, alkylsulfonate and naphthalene sulfonate etc.；The wetting agent
Dosage be total formulation weight 1-10%, such as 2-9%, 3-8% or 4-7%, preferably 3-7%, such as 4-6% or 5-6%；
And remaining is filler, one in diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite and clay etc.
Kind is a variety of.
When composition pesticide of the present invention is configured to water dispersible granules, the auxiliary agent includes dispersant, wetting agent, collapses
Solve agent, binder and/or filler etc..Wherein：Dispersant be selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate and
It is one or more in alkylnaphthalene sulfonate formaldehyde condensation products etc.；The dosage of the dispersant is the 1-10% of total formulation weight,
Such as 2-9%, 3-8% or 4-7%, preferably 3-7%, 4-6% or 5-6%；Wetting agent is selected from polyoxyethylene alcohol, alkylsurfuric acid
It is one or more in salt, alkylsulfonate and naphthalene sulfonate etc.；The dosage of the wetting agent is the 1-10% of total formulation weight,
Such as 2-9%, 3-8% or 4-7%, preferably 2-7%, such as 3-6% or 4-5%；Disintegrant be selected from ammonium sulfate, urea, sucrose,
It is one or more in glucose, citric acid, succinic acid and sodium bicarbonate etc.；The dosage of the disintegrant is total formulation weight
0.1-10%, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4% or 1-3%；Binder
It is one or more in diatomite, cornstarch, PVA, carboxymethyl (ethyl) cellulose family and microcrystalline cellulose class etc.；Institute
The dosage for stating binder is the 0.1-10%, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6% of total formulation weight, preferably
1-5%, such as 2-4% or 1-3%；And remaining be filler, selected from diatomite, kaolin, white carbon, fine particle calcium carbonate, sepiolite,
It is one or more in talcum powder, attapulgite and clay etc..
When composition pesticide of the present invention is configured to dispersible oil-suspending agent, the auxiliary agent includes dispersant, wetting
Agent, thickener, preservative, antifoaming agent, antifreezing agent and/or grease auxiliary agent etc..Wherein：Dispersant be selected from polycarboxylate salt dispersant,
Rosin dispersant, phosphoric acid ester dispersant, macromolecule emulsion dispersant, alkyl naphthalene sulfonic acid condensation polymer sodium salt, alkyl naphthalene sulfonic acid
Salt condensation polymer, ethyoxyl triphenylethylene phenol phosphate, organophosphorus compounds, combed high-molecular copolymer, polyoxyethylene aryl ether,
It is one or more in polyoxyethylene aryl phenyl ether phosphoric acid amine salt and styrene phenol polyoxyethylene anionic dispersing agents etc.；
The dosage of the dispersant is the 1-8% of total formulation weight, such as 2-7%, 1-7% or 2-8%, preferably 3-6%, such as 4-
5%；Wetting agent is selected from the poly- base ether formaldehyde condensation products sulfate of alkylphenol-polyethenoxy, aryl sulfonate formaldehyde condensates, alkyl
Naphthalene sulfonate and anion humectant mixture, isopropyl naphthalene sulfonate, normal-butyl naphthalene sulfonate, alkylphenol-polyethenoxy base ether
Phosphate, phenethyl phenol polyoxyethylene groups ether phosphate, alkyl sulfate, sulfosuccinate, ethoxy alcohol, block copolymerization
It is one or more in object, polyxyethylated alcohol and fatty alcohol polyoxyethylene ether etc.；The dosage of the wetting agent is total formulation weight
The 1-6% of amount, such as 2-5%, 1-5% or 1-4%, preferably 2-4%, such as 2-3% or 4-5%；Thickener be selected from xanthans,
It is one or more in aluminium-magnesium silicate and organobentonite etc.；The dosage of the thickener is the 0.1-10% of total formulation weight,
Such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 1-5%, such as 2-4%, 3-5% or 2-3%；Preservative selects
From one or more in benzoic acid, sodium benzoate and BIT (1,2-benzisothiazolin-3-one) etc.；The use of the preservative
Amount is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 0.2-2%, such as
0.5-1.5%, 1-1.5% or 1-2%；Antifoaming agent is organic silicon antifoaming agent etc.；The dosage of the antifoaming agent is total formulation weight
The 0.1-10% of amount, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6%, preferably 0.4-1.0%, for example, 0.6-0.8% or
0.5-1%；Antifreezing agent is one or more in ethylene glycol, propylene glycol, glycerine, urea and inorganic salts such as sodium chloride；
The dosage of the antifreezing agent is the 0.1-10% of total formulation weight, such as 1-9%, 2-8%, 1-8%, 1-7% or 1-6% are excellent
Select 1-5%, such as 2-4%, 3-5% or 2-3%；And remaining is grease analog assistant, selected from methyl oleate, vegetable oil, animal
It is one or more in oil etc..
Specific implementation mode
Following embodiment is only that the present invention is furture elucidated, without limiting the invention to these specific implementation modes
Intention.One skilled in the art would recognize that all present invention encompasses may include in Claims scope
Alternative, improvement project and equivalent program.
Inventor is by alkene oxime amine and benzoxazole, imazalil, cyazofamid or metconazole mixture, with cucumber powdery mildew's pathogen, Huang
Melon Pseudoperonospora cubensis, tomato early blight bacterium, Colletotrichum capsici, fusarium graminearum are object, carry out co-toxicity test, specifically
Test situation and result are as follows：
Medicament uses potting seedling measuring method to the joint toxicity measuring experiment of cucumber powdery mildew's pathogen.
The culture of cucumber powdery mildew's pathogen and the preparation of inoculation material：Never Huang was acquired with applying the cucumber cultivation of fungicide
Melon powdery mildew leaf, moisturizing is placed in 23 DEG C, is cultivated under the conditions of relative humidity=50%, 12h alternation of light and darkness in culture dish, pending
After generating a large amount of new spores on sick blade, spore is eluted with sterile water, is configured to a concentration of 105 spore/mL's
Spore suspension is used for inoculation test.
For trying the preparation of cucumber plant：By the cultivation of susceptible cucumber variety in a diameter of 15cm, the pot for growing seedlings of high 12cm, set
It is cultivated in glasshouse, after its length to 3-4 leaf phase, selects the consistent plant of growing way and tested.
Toxicity test of the medicament to cucumber powdery mildew's pathogen：Prepared graded series liquid hand sprayer will be shifted to an earlier date,
(pressure 1bar, nozzle diameter:It 0.3mm) uniformly sprays for trying cucumber plant blade surface, small droplet is covered with leaf table, but not
It can drip as standard.After liquid sprays, natural air drying.Each concentration is inoculated with 6 melon seedlings, 3 repetitions.It, will after dispenser for 24 hours
Prepared spore suspension even spraying is seeded in the true leaf surface of cucumber plant in advance.After moisturizing 12h, it is placed in daylight glass
It is cultivated in greenhouse.
As a result it investigates：According to National Standard of the People's Republic of China " pesticide field efficacy medicine test criterion (GB/T
Regulation in 17980.30-2000) " carries out classification and disease index investigation, is recorded by following stage division.
Stage division is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less entire leaf area；
3 grades：Lesion area accounts for entire leaf area 6% -10%；
5 grades：Lesion area accounts for entire leaf area 11% -20%；
7 grades：Lesion area accounts for entire leaf area 21% -40%；
9 grades：Lesion area accounts for 40% or more entire leaf area.
Calculation formula：
Disease index may be simply referred to as disease and refer to.
Co-toxicity coefficient is the coefficient for evaluating the variation of virulence when two or more pesticide activity component is used with.
According to control effect, virulence regression equation and EC are found out50Value；Two are evaluated according to the abundant co-toxicity coefficient methods of Sun Yun (CTC)
The synergy type of kind active constituents of medicine difference mixed ratio：If co-toxicity coefficient is more than 120, show there is synergistic effect；If
Less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
Medicament uses potting seedling measuring method to the joint toxicity measuring experiment of bacterium of downy mildew of cucumber.To each proportioning test specimens
Product carry out the foliar spray processing of various concentration.The 2nd day inoculation cucumber downy mildew sporangia suspension, inoculation are placed on after processing
Phjytotron (condition：Temperature：25 DEG C of daytime, 20 DEG C of night, relative humidity：It 95-99%) cultivates, is placed on greenhouse (25 within 24 hours
DEG C ± 1 DEG C) normal management, investigation prevention effect after 6 days.
According to control effect, virulence regression equation and EC90 values are found out；Two are evaluated according to the abundant co-toxicity coefficient methods of Sun Yun (CTC)
The synergy type of kind active constituents of medicine difference mixed ratio：If co-toxicity coefficient is more than 120, show there is synergistic effect；If
Less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
Medicament uses bacterium to the joint toxicity measuring experiment of tomato early blight bacterium, Colletotrichum capsici, fusarium graminearum
Silk growth rate method is measured.The PDA culture medium melted is cooled to 60-70 DEG C, quantitative medicine is added by designed concentration
The toxic culture medium containing different pesticide solutions is made in agent, after it is fully cooled, inoculation diameter 5mm for trying pathogen bacterium
Piece is placed in culture (26 ± 1 DEG C) in incubator, is investigated after 7 days.Measured respectively when investigation each handle for try pathogen
Colony diameter calculates bacteriostasis rate according to the following formula.
Bacteriostasis rate (%)=(control colony diameter-processing colony diameter)/control colony diameter × 100%
According to bacteriostasis rate, virulence regression equation and EC are found out50Value；According to the abundant co-toxicity coefficient methods of Sun Yun (CTC), (this is science
Upper common formulation) two kinds of active constituents of medicine difference mixed ratios of evaluation synergy type：If co-toxicity coefficient is more than 120,
Show there is synergistic effect；If being less than 80, it is shown to be antagonism；Between 80~120, it is shown to be summation action.
Calculation formula：
B in the TI × mixture of content (%)+B agent of A in TI × mixture of theoretical toxicity index (TTI)=A agent of mixture
Content (%)
1. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in cucumber powdery mildew's pathogen room
From table 1 it follows that alkene oxime amine and benzoxazole mixture have a higher activity to cucumber powdery mildew's pathogen, 11
EC for trial than mixture50Value is between 0.52mg/L-4.84mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with benzoxazole mixture prevention powdery mildew of cucumber to close
Rationality and feasibility.
2. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in tomato early blight bacterium room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=4.6907+1.7215x | 1.51 | 0.9887 | - |
| Benzoxazole | Y=5.4726+1.6346x | 0.62 | 0.9867 | - |
| Alkene oxime amine:Benzoxazole=60:1 | Y=4.9014+1.5980x | 1.15 | 0.9732 | 128.3 |
| Alkene oxime amine:Benzoxazole=40:1 | Y=4.9154+1.5756x | 1.13 | 0.9714 | 129.1 |
| Alkene oxime amine:Benzoxazole=20:1 | Y=5.0186+1.4557x | 0.97 | 0.9653 | 145.7 |
| Alkene oxime amine:Benzoxazole=10:1 | Y=5.1008+1.4462x | 0.85 | 0.9861 | 157.1 |
| Alkene oxime amine:Benzoxazole=5:1 | Y=5.2631+1.4224x | 0.65 | 0.9803 | 187.5 |
| Alkene oxime amine:Benzoxazole=1:1 | Y=5.5410+1.7097x | 0.48 | 0.9952 | 183.1 |
| Alkene oxime amine:Benzoxazole=1:5 | Y=5.7517+1.7555x | 0.37 | 0.9893 | 185.8 |
| Alkene oxime amine:Benzoxazole=1:10 | Y=5.6883+1.8465x | 0.42 | 0.9892 | 156.0 |
| Alkene oxime amine:Benzoxazole=1:20 | Y=5.5153+1.4962x | 0.45 | 0.9735 | 141.8 |
| Alkene oxime amine:Benzoxazole=1:40 | Y=5.4996+1.5312x | 0.47 | 0.9814 | 133.8 |
| Alkene oxime amine:Benzoxazole=1:60 | Y=5.4664+1.5056x | 0.49 | 0.9827 | 127.8 |
From Table 2, it can be seen that alkene oxime amine and benzoxazole mixture have a higher activity to tomato early blight bacterium, 11
EC for trial than mixture50Value is between 0.37mg/L-1.15mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with benzoxazole mixture prevention early blight of tomato
Property and feasibility.
3. alkene oxime amine of table and benzoxazole and combinations thereof are to joint toxicity measuring result in Colletotrichum capsici room
From table 3 it is observed that alkene oxime amine and benzoxazole mixture have a higher activity to Colletotrichum capsici, 11
EC for trial than mixture50Value is between 0.14mg/L-2.73mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and benzoxazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with benzoxazole mixture prevention pepper anthracnose
Property and feasibility.
4. alkene oxime amine of table and cyazofamid and combinations thereof are to joint toxicity measuring result in cucumber downy mildew room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=3.9103+1.6096x | 4.75 | 0.9881 | - |
| Cyazofamid | Y=3.3349+1.7085x | 9.43 | 0.9894 | - |
| Alkene oxime amine:Cyazofamid=60:1 | Y=4.1949+1.3996x | 3.76 | 0.9805 | 127.4 |
| Alkene oxime amine:Cyazofamid=40:1 | Y=4.2022+1.3970x | 3.72 | 0.9807 | 129.3 |
| Alkene oxime amine:Cyazofamid=20:1 | Y=4.2581+1.3472x | 3.55 | 0.9830 | 137.0 |
| Alkene oxime amine:Cyazofamid=10:1 | Y=4.2313+1.4901x | 3.28 | 0.9863 | 151.7 |
| Alkene oxime amine:Cyazofamid=5:1 | Y=4.2399+1.5331x | 3.13 | 0.9881 | 165.4 |
| Alkene oxime amine:Cyazofamid=1:1 | Y=4.1689+1.3929x | 3.95 | 0.9869 | 159.9 |
| Alkene oxime amine:Cyazofamid=1:5 | Y=3.9696+1.5039x | 4.84 | 0.9839 | 167.4 |
| Alkene oxime amine:Cyazofamid=1:10 | Y=3.7849+1.6553x | 5.42 | 0.9737 | 159.7 |
| Alkene oxime amine:Cyazofamid=1:20 | Y=3.7083+1.6327x | 6.18 | 0.9862 | 145.8 |
| Alkene oxime amine:Cyazofamid=1:40 | Y=3.6215+1.6725x | 6.67 | 0.9898 | 138.1 |
| Alkene oxime amine:Cyazofamid=1:60 | Y=3.6796+1.5201x | 7.38 | 0.9796 | 125.7 |
As can be seen from Table 4, alkene oxime amine and cyazofamid mixture have a higher activity to bacterium of downy mildew of cucumber, 11
EC for trial than mixture50Value is between 3.13mg/L-7.38mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and cyazofamid
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has rationally with cyazofamid mixture prevention cucumber downy mildew
Property and feasibility.
5. alkene oxime amine of table and imazalil and combinations thereof are to joint toxicity measuring result in cucumber powdery mildew's pathogen room
As can be seen from Table 5, alkene oxime amine and imazalil mixture have a higher activity to cucumber powdery mildew's pathogen, 11
EC for trial than mixture50Value is between 1.43mg/L-5.35mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and imazalil
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with imazalil mixture prevention powdery mildew of cucumber to close
Rationality and feasibility.
6. alkene oxime amine of table and imazalil and combinations thereof are to joint toxicity measuring result in Colletotrichum capsici room
| Medicament | Regression equation | EC50(mg/L) | Related coefficient | Co-toxicity coefficient |
| Alkene oxime amine | Y=3.7818+1.6239x | 5.63 | 0.9854 | - |
| Imazalil | Y=6.1115+1.3633x | 0.15 | 0.9832 | - |
| Alkene oxime amine:Imazalil=60:1 | Y=4.4298+1.2873x | 2.77 | 0.9867 | 127.1 |
| Alkene oxime amine:Imazalil=40:1 | Y=4.5602+1.2918x | 2.19 | 0.9827 | 135.9 |
| Alkene oxime amine:Imazalil=20:1 | Y=4.6946+1.5753x | 1.56 | 0.9790 | 131.7 |
| Alkene oxime amine:Imazalil=10:1 | Y=5.1252+1.4794x | 0.82 | 0.9952 | 158.9 |
| Alkene oxime amine:Imazalil=5:1 | Y=5.3822+1.1954x | 0.48 | 0.9866 | 165.5 |
| Alkene oxime amine:Imazalil=1:1 | Y=5.7929+1.0438x | 0.17 | 0.9793 | 171.9 |
| Alkene oxime amine:Imazalil=1:5 | Y=6.1120+1.1724x | 0.11 | 0.9735 | 162.8 |
| Alkene oxime amine:Imazalil=1:10 | Y=6.0167+0.9735x | 0.09 | 0.9614 | 182.8 |
| Alkene oxime amine:Imazalil=1:20 | Y=6.0539+1.0682x | 0.10 | 0.9789 | 157.3 |
| Alkene oxime amine:Imazalil=1:40 | Y=6.0409+1.1477x | 0.12 | 0.9935 | 128.0 |
| Alkene oxime amine:Imazalil=1:60 | Y=6.0105+1.0686x | 0.11 | 0.9893 | 138.6 |
As can be seen from Table 6, alkene oxime amine and imazalil mixture have a higher activity to Colletotrichum capsici, 11
EC for trial than mixture50Value is between 0.09mg/L-2.77mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and imazalil
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with imazalil mixture prevention pepper anthracnose to close
Rationality and feasibility.
7. alkene oxime amine of table and metconazole and combinations thereof are to joint toxicity measuring result in fusarium graminearum room
As can be seen from Table 7, alkene oxime amine and metconazole mixture have a higher activity to fusarium graminearum, 11
EC for trial than mixture50Value is between 0.07mg/L-0.21mg/L；The total poison of 11 proportioning mixtures of alkene oxime amine and metconazole
Coefficient is all higher than 120, shows apparent synergistic effect.Illustrate that alkene oxime amine has with metconazole mixture prevention wheat scab to close
Rationality and feasibility.
1, example of formulations
Percentage composition is mass percent in all formulations proportioning.
Embodiment 1：5% alkene oxime amine benzoxazole microemulsion (ME)
Weigh 2.5g alkene oxime amines active compound, 2.5g benzoxazole active compound, 5g N-Methyl pyrrolidones, 10g isopropanols, 4.5g
Agriculture breast 600#, 5.5g agriculture breast 1601#, adds water to complement to 100g.Active compound, solvent, emulsifier are added together, make to be dissolved into uniformly
Oil phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, oil phase is mixed with water, physical and chemical performance is made
Preferable microemulsion.
Embodiment 2：81% alkene oxime amine benzoxazole wettable powder (WP)
1g alkene oxime amines active compound, 80g benzoxazole active compound, 1g neopelexes, 10g sodium lignin sulfonates are weighed,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 3：61% alkene oxime amine benzoxazole water dispersible granules (WG)
Weigh the sodium salt of 1g alkene oxime amines active compound, 60g benzoxazole active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 14g ammonium sulfate,
2g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 17.6g cornstarch.It is uniformly mixed, through gas
It after stream crushes, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 4：41% alkene oxime amine benzoxazole missible oil (EC)
Weigh 1g alkene oxime amines active compound, 40g benzoxazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxyethylene
Ether 2g, nonylphenol polyoxyethylene ether 2g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 5：42% alkene oxime amine benzoxazole suspending agent (SC)
Weigh 2g alkene oxime amines active compound, 40g benzoxazole active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 6：The 22% dispersible oil-suspending agent of alkene oxime amine benzoxazole (OD)
Weigh 2g alkene oxime amines active compound, 20g benzoxazole active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 7：24% alkene oxime amine benzoxazole aqueous emulsion (EW)
Weigh 4g alkene oxime amines active compound, 20g benzoxazole active compound, 150# solvent naphthas 24g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.5g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 4g Silwet 806 increase
Imitate agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：It is organically-modified
Siloxanes), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain water and milk
Agent.
Embodiment 8：10% alkene oxime amine benzoxazole microemulsion (ME)
Weigh 5g alkene oxime amines active compound, 5g benzoxazole active compounds, 5g N-Methyl pyrrolidones, 10g isopropanols, 4g agriculture breasts
600#, 6g agriculture breast 1602#, add water to complement to 100g.Active compound, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；
Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, oil phase is mixed with water, it is preferable that physical and chemical performance is made
Microemulsion.
Embodiment 9：30% alkene oxime amine benzoxazole suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g benzoxazole active compounds, 5g rosins dispersion moisture agent, 1.5g polycarboxylic acid salts profit
Hygroscopic water powder, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 10：44% alkene oxime amine benzoxazole missible oil (EC)
Weigh 40g alkene oxime amines active compound, 4g benzoxazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxyethylene
Ether 2g, nonylphenol polyoxyethylene ether 1.5g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 11：21% alkene oxime amine benzoxazole microcapsule suspending agent (CS)
20g alkene oxime amines active compound, 1g benzoxazole active compounds are weighed, (Bao Lige Products, appear below Ultrazine NA
With herein) 1g, Sodium Polyacrylate 2g, polyureas performed polymer 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha
15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans 0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent
In oil solvent, uniform oil-phase solution is obtained；Aqueous solution containing emulsified dispersant is added thereto, with being vigorously stirred, prepares
Go out using solid active compound, solvent naphtha as oil phase, using aqueous solution containing emulsified dispersant as the O/W type stable emulsions of water phase.It will be advance
Prepared urea-formaldehyde polyurea prepolymer is added in lotion, using low content hydrochloric acid regulating system pH value, in acid catalysed conditions
Lower generation polymerisation, makes oil phase substance be wrapped, and forms microcapsule suspending agent.Thickening is added into this microcapsule suspending agent
Agent, antifreeze, stir evenly to get microcapsule suspending agent.
Embodiment 12：61.5% alkene oxime amine benzoxazole water dispersible granules (WG)
Weigh the sodium salt of 60g alkene oxime amines active compound, 1.5g benzoxazole active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 28.5g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 13：12.2% alkene oxime amine benzoxazole granule (GR)
Weigh 12g alkene oxime amines active compound, 0.2g benzoxazole active compound, clay 50g, cornstarch 8g, white carbon 4g, lignin
Sodium sulfonate 1g, polylactic acid PLA 3g, 2g Arabic gum, 3.2g lauryl sodium sulfate add clay to complement to 100g.Add water 10g,
It is uniformly mixed, carries out extruder grain, dry granule product.
Embodiment 14：81% alkene oxime amine benzoxazole wettable powder (WP)
Weigh 80g alkene oxime amines active compound, 1g benzoxazole active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 15：24.3% alkene oxime amine imazalil suspending agent (SC)
Weigh 0.3g alkene oxime amines active compound, 24g imazalil active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts profit
Hygroscopic water powder, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 16：30.5% alkene oxime amine Imazalil EC (EC)
Weigh 0.5g alkene oxime amines active compound, 30g imazalil active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 17：The 20.5% dispersible oil-suspending agent of alkene oxime amine imazalil (OD)
Weigh 0.5g alkene oxime amines active compound, 20g imazalils active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 18：31.5% alkene oxime amine imazalil suspending agent (SC)
Weigh 1.5g alkene oxime amines active compound, 30g imazalil active compounds, 5.2g rosins dispersion moisture agent, 1.8g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 19：27.5% alkene oxime amine imazalil microcapsule suspending agent (CS)
Weigh 2.5g alkene oxime amines active compound, 25g imazalil active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas
Performed polymer 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthan
Glue 0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；
Aqueous solution containing emulsified dispersant is added thereto, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, with
Aqueous solution containing emulsified dispersant is the O/W type stable emulsions of water phase.Advance prepared urea-formaldehyde polyurea prepolymer is added
Enter in lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
It wraps, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 20：60% alkene oxime amine imazalil water dispersible granules (WG)
Weigh the sodium salt of 10g alkene oxime amines active compound, 50g imazalils active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 30g bentonites.It is uniformly mixed, through air-flow
It after crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 21：30% alkene oxime amine imazalil suspending agent (SC)
Weigh 15g alkene oxime amines active compound, 15g imazalil active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 22：18% alkene oxime amine imazalil aqueous emulsion (EW)
Weigh 15g alkene oxime amines active compound, 3g imazalils active compound, 150# solvent naphthas 18g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 23：22% alkene oxime amine Imazalil EC (EC)
Weigh 20g alkene oxime amines active compound, 2g imazalil active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 24：The 21% dispersible oil-suspending agent of alkene oxime amine imazalil (OD)
Weigh 20g alkene oxime amines active compound, 1g imazalils active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 25：41% alkene oxime amine imazalil water dispersible granules (WG)
Weigh the sodium salt of 40g alkene oxime amines active compound, 1g imazalils active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 49g cornstarch.It is uniformly mixed, through gas
It after stream crushes, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 26：5% alkene oxime amine Imazalil EC (EC)
4.918g alkene oxime amines active compound, 0.082g imazalil active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 27：81% alkene oxime amine imazalil wettable powder (WP)
Weigh 80g alkene oxime amines active compound, 1g imazalil active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 28：81% alkene oxime amine cyazofamid wettable powder (WP)
Weigh 1g alkene oxime amines active compound, 80g cyazofamid active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 29：61% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 1g alkene oxime amines active compound, 60g cyazofamid active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 30：24.6% alkene oxime amine cyazofamid missible oil (EC)
Weigh 0.6g alkene oxime amines active compound, 24g cyazofamid active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 31：The 21% dispersible oil-suspending agent of alkene oxime amine cyazofamid (OD)
Weigh 1g alkene oxime amines active compound, 20g cyazofamids active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 32：33% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 3g alkene oxime amines active compound, 30g cyazofamid active compounds, 5g rosins dispersion moisture agent, 2g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 33：18% alkene oxime amine cyazofamid microcapsule suspending agent (CS)
Weigh 3g alkene oxime amines active compound, 15g cyazofamid active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas is pre-
Aggressiveness 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans
0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；To
Aqueous solution containing emulsified dispersant is wherein added, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, to contain
The aqueous solution of emulsifying dispersant is the O/W type stable emulsions of water phase.It prepared urea-formaldehyde polyurea prepolymer will be added in advance
In lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
Get up, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 34：40% alkene oxime amine cyazofamid water dispersible granules (WG)
Weigh 20g alkene oxime amines active compound, 20g cyazofamids active compound, 5g sodium lignin sulfonates, 4g ammonium sulfate, 0.6g alkylnaphthalenes
Sulfonate and anion humectant mixture, 0.4g sodium benzoates and 50g bentonites.It is uniformly mixed, after air-flow crushing, is making
It is granulated in grain machine, then dries, sieves up to granular product.
Embodiment 35：30% alkene oxime amine cyazofamid suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g cyazofamid active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 36：11% alkene oxime amine cyazofamid aqueous emulsion (EW)
Weigh 10g alkene oxime amines active compound, 1g cyazofamids active compound, 150# solvent naphthas 11g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 37：63% alkene oxime amine cyazofamid missible oil (EC)
Weigh 60g alkene oxime amines active compound, 3g cyazofamid active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 38：The 20.5% dispersible oil-suspending agent of alkene oxime amine cyazofamid (OD)
Weigh 20g alkene oxime amines active compound, 0.5g cyazofamids active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 39：54.9% alkene oxime amine cyazofamid water dispersible granules (WG)
Weigh the sodium salt of 54g alkene oxime amines active compound, 0.9g cyazofamids active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 35.1g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 40：5% alkene oxime amine cyazofamid missible oil (EC)
4.938g alkene oxime amines active compound, 0.062g cyazofamid active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
Embodiment 41：81% alkene oxime amine metconazole wettable powder (WP)
Weigh 1g alkene oxime amines active compound, 80g metconazole active compounds, 1g neopelexes, 10g sodium lignin sulfonates,
Precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, are pulverized and mixed through airslide disintegrating mill, wettable powder is obtained.
Embodiment 42：61% alkene oxime amine metconazole suspending agent (SC)
Weigh 1g alkene oxime amines active compound, 60g metconazole active compounds, 6g rosins dispersion moisture agent, 1g polycarboxylic acid salts wetting
Dispersant, 0.3g xanthans, 1.5g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g
Organically-modified silica alkane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 43：24.6% alkene oxime amine metconazole missible oil (EC)
Weigh 0.6g alkene oxime amines active compound, 24g metconazole active compounds, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyoxy second
Alkene ether 2g, nonylphenol polyoxyethylene ether 1.5g, 200# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, composition is made
Missible oil.
Embodiment 44：The 21% dispersible oil-suspending agent of alkene oxime amine metconazole (OD)
Weigh 1g alkene oxime amines active compound, 20g metconazoles active compound, 17g TERMUL 3015 (nonionic surfactant), 5g
TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added to
10min is sheared in high-shear emulsion machine, then after being sanded with sand mill, obtain dispersible oil-suspending agent.
Embodiment 45：33% alkene oxime amine metconazole suspending agent (SC)
Weigh 3g alkene oxime amines active compound, 30g metconazole active compounds, 5g rosins dispersion moisture agent, 2g polycarboxylic acid salts wetting
Dispersant, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one), 0.3g have
Machine modified siloxane antifoaming agent, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and shear 10min,
After being sanded again with sand mill, suspending agent is obtained.
Embodiment 46：18% alkene oxime amine metconazole microcapsule suspending agent (CS)
Weigh 3g alkene oxime amines active compound, 15g metconazole active compounds, Ultrazine NA 1g, Sodium Polyacrylate 2g, polyureas is pre-
Aggressiveness 10g, styrene maleic anhydride copolymer 1g, 150# solvent naphtha 15g, hydrochloric acid 3g, sodium hydroxide 0.01g, xanthans
0.01g, polyvinyl alcohol 2g, remaining water are supplied.Active ingredient is dissolved in solvent oil solvent, uniform oil-phase solution is obtained；To
Aqueous solution containing emulsified dispersant is wherein added, with being vigorously stirred, makes using solid active compound, solvent naphtha as oil phase, to contain
The aqueous solution of emulsifying dispersant is the O/W type stable emulsions of water phase.It prepared urea-formaldehyde polyurea prepolymer will be added in advance
In lotion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalyzed conditions, and oil phase substance is made to be wrapped
Get up, forms microcapsule suspending agent.Thickener, antifreeze are added into this microcapsule suspending agent, stirs evenly to get microcapsule suspension
Agent.
Embodiment 47：40% alkene oxime amine metconazole water dispersible granules (WG)
Weigh 20g alkene oxime amines active compound, 20g metconazoles active compound, 5g sodium lignin sulfonates, 4g ammonium sulfate, 0.6g alkylnaphthalenes
Sulfonate and anion humectant mixture, 0.4g sodium benzoates and 50g bentonites.It is uniformly mixed, after air-flow crushing, is making
It is granulated in grain machine, then dries, sieves up to granular product.
Embodiment 48：30% alkene oxime amine metconazole suspending agent (SC)
Weigh 25g alkene oxime amines active compound, 5g metconazole active compounds, 6g sodium lignin sulfonates dispersion moisture agent, 1g polycarboxylates
Class wetting dispersing agent, 0.4g xanthans, 1g aluminium-magnesium silicates, 5g ethylene glycol, 0.5g BIT (1,2-benzisothiazolin-3-one),
The organically-modified silica alkane antifoaming agent of 0.3g, deionized water add to 100g.Above-mentioned raw materials are added in high-shear emulsion machine and are sheared
10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 49：11% alkene oxime amine metconazole aqueous emulsion (EW)
Weigh 10g alkene oxime amines active compound, 1g metconazoles active compound, 150# solvent naphthas 11g, 4g SK-5050 (ingredients：Polyoxy second
Alkene aryl ether), 3.2g SK-551 (ingredients：Styrene phenol polyoxyethylene anionic dispersing agents), 806 synergy of 4gSilwet
Agent (ingredient：Organic silicon), 0.18g xanthans, 4g ethylene glycol, 0.3g benzoic acid, 0.5g antifoaming agent (ingredients：Organic modified silicas
Oxygen alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 50：63% alkene oxime amine metconazole missible oil (EC)
Weigh 60g alkene oxime amines active compound, 3g metconazole active compounds, calcium dodecyl benzene sulfonate 5.5g, phenethyl phenol polyoxy second
Alkene ether 1.5g, nonylphenol polyoxyethylene ether 1.5g, 150# is low, and naphthalene type solvent naphtha adds to 100g.It mixes to homogeneous liquid, combination is made
Object missible oil.
Embodiment 51：The 20.5% dispersible oil-suspending agent of alkene oxime amine metconazole (OD)
Weigh 20g alkene oxime amines active compound, 0.5g metconazoles active compound, 17g TERMUL 3015 (nonionic surfactant),
5g TERSPERSE2501 (non-ionic dispersing agent), 1.0g organobentonites, methyl oleate add to 100g.Above-mentioned raw materials are added
To shearing 10min in high-shear emulsion machine, then after being sanded with sand mill, dispersible oil-suspending agent is obtained.
Embodiment 52：54.9% alkene oxime amine metconazole water dispersible granules (WG)
Weigh the sodium salt of 54g alkene oxime amines active compound, 0.9g metconazoles active compound, 5g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate,
0.6g alkylnaphthalene sulfonates and anion humectant mixture, 0.4g sodium benzoates and 35.1g cornstarch.It is uniformly mixed, warp
It after air-flow crushing, is granulated in comminutor, then dries, sieves up to granular product.
Embodiment 53：5% alkene oxime amine metconazole missible oil (EC)
4.938g alkene oxime amines active compound, 0.062g metconazole active compounds are weighed, calcium dodecyl benzene sulfonate 5g, phenethyl phenol are poly-
Ethylene oxide ether 2g, nonylphenol polyoxyethylene ether 1g, 150# solvent naphtha add to 100g.It mixes to homogeneous liquid, composition missible oil is made.
2 field control effectiveness tests
2.1 different embodiments prevent powdery mildew of cucumber field control effectiveness test
Experiment carries out in Shouguang City of Shandong Province heliogreenhouse, and preceding stubble is Chinese cabbage, and cucumber spacing in the rows is 30cm, and line-spacing is
60cm.Experiment sets 49 processing, 30 square metres of plot area；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, early stage dispenser, dispenser 2 times, be spaced 7 days, before first time medicine, before second of dispenser, second
Disease index is investigated respectively within 7 days after secondary dispenser.5 points of investigation are taken at random per cell, are seted the tone per solid point and are looked into two plants, depending on incidence
Every plant is investigated whole blades from bottom to top, records the sick numbers of sheets at different levels, and severity Scaling takes 0,1,3,5,7,9 totally six ranks.Point
Grade standard is as follows：
0 grade：It is disease-free；
1 grade：Scab accounts for 5% or less leaf area；
3 grades：Scab accounts for leaf area 6%~10%；
5 grades：Scab accounts for leaf area 11%~25%；
7 grades：Scab accounts for leaf area 26%~50%；
9 grades：Scab accounts for 50% or more leaf area.
Drug effect computational methods：
In formula：CK0--- disease index before blank district dispenser；CK1--- disease index after blank district dispenser；
PT0--- disease index before chemicals treatment district dispenser；PT1--- the state of an illness after chemicals treatment district dispenser.
Safety observations：Influence of each chemicals treatment district of visual observations to cucumber growth in 1,3,7 day after each medicine, clearly has
No poisoning occurs.Test result and analysis：
The different embodiments of table 8 are to powdery mildew of cucumber field control effect
Alkene oxime amine single dose is slightly below imazalil, benzoxazole, metconazole list to the preventive effect of powdery mildew of cucumber as shown in Table 8
Agent is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of powdery mildew of cucumber by each embodiment after compounding and obviously carries
Height, the control effect for compounding the bactericidal composition of mixture are generally higher by than the control effect of any one separate constituent
10% or more.It is apparent to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have powdery mildew of cucumber
Synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination cucumber growth, each treatment agent does not occur to cucumber
Poisoning phenomenon.
2.2 different embodiments prevent cucumber downy mildew field control effectiveness test
Experiment carries out in the heliogreenhouse of Tai'an Daiyue District room villages and small towns.It is experimental field sandy loam, rich water is sufficient.Cucumber is
August is just colonized, 80 centimetres of big row, 50 centimetres of small row, 35 centimetres of spacing in the rows, double ridge duplicate rows cultivations.Experiment sets 49 processing, cell face
30 square metres of product；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, in cucumber downy mildew early stage first time dispenser, second of dispenser after 7 days, altogether dispenser 2 times.The
7 days investigation state of an illness after 7 days and second of medicine after dispenser.5 points of investigation are taken at random per cell, and every is looked into two plants, depending on feelings of falling ill
Every plant of condition investigates 5~15 leaves (investigation determines that identical leaf position is investigated from bottom to top per cell every time) from bottom to top, records each
The sick number of sheets of grade, severity Scaling take 0,1,3,5,7,9 totally six ranks.Grade scale is as follows：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 10% or less entire leaf area；
3 grades：Lesion area accounts for entire leaf area 10%~20%；
5 grades：Lesion area accounts for entire leaf area 21%~30%；
7 grades：Lesion area accounts for entire leaf area 31%~50%；
9 grades：Lesion area accounts for 50% or more entire leaf area.
Drug effect computational methods
Test results and analysis
The different embodiments of table 9 are to cucumber downy mildew field control effect
Alkene oxime amine single dose is slightly below cyazofamid single dose to the preventive effect of cucumber downy mildew as shown in Table 9, higher than imazalil, nitrile
Benzene azoles, metconazole single dose.It is all significantly improved compared to single dose to the preventive effect of cucumber downy mildew by each embodiment after compounding,
The control effect for compounding the bactericidal composition of mixture is generally higher by 10% than the control effect of any one separate constituent
More than.Illustrate that alkene oxime amine has apparent synergy with imazalil, benzoxazole, cyazofamid, metconazole compounding to cucumber downy mildew
Effect.Field is estimated, and within the range of experimental dose, normal for examination cucumber growth, each treatment agent does not occur the medicine to cucumber
Evil phenomenon.
2.3 different embodiments prevent early blight of tomato field control effectiveness test
Experimental plot is located at the Senior Residents in Fengxian District of Shanghai towns Zhuan Hang, and topography is flat, and irrigation and drainage are convenient.It is tomato for examination vegetables, kind is
Zhejiang powder 202.Experiment sets 49 processing, 30 square metres of plot area；Often processing is repeated 3 times, and totally 147 cells, cell are arranged at random
Row.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Investigation method, time and number：First time dispenser before the onset of early blight of tomato, second of dispenser after 7 days, altogether dispenser
2 times.7 days investigation state of an illness after 7 days and second of medicine after first time dispenser.5 points of investigation are taken at random per cell, and every is looked into two plants, often
Strain divides upper, middle and lower to investigate 10 leaves, accounts for the percentage of entire leaf area with the lesion area on every a piece of leaf to be classified.
Stage division (as unit of blade)：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for 5% or less blade area；
3 grades：Lesion area accounts for the 6%-10% of blade area；
5 grades：Lesion area accounts for the 11%-25% of blade area；
7 grades：Lesion area accounts for the 26%-50% of blade area；
9 grades：The percentage that lesion area accounts for blade area is more than 50%.
Drug effect computational methods：
In formula：CK1--- disease index after blank district dispenser；PT1--- disease index after chemicals treatment district dispenser；
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis
The different embodiments of table 10 are to early blight of tomato field control effect
Alkene oxime amine single dose is to the preventive effect of early blight of tomato and imazalil, benzoxazole, metconazole single dose as shown in Table 10
Preventive effect is suitable, is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of early blight of tomato by each embodiment after compounding
It significantly improves, the control effect for compounding the bactericidal composition of mixture is more universal than the control effect of any one separate constituent
It is higher by 10% or more.It is bright to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have early blight of tomato
Aobvious synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination tomato growth, each treatment agent does not occur pair
The poisoning phenomenon of tomato.
2.4 different embodiments prevent pepper anthracnose field control effectiveness test
Experiment is middle green pepper No. 4 for examination capsicum variety in Jining City in Shandong Province Jinxiang County.Experiment sets 49 processing, cell face
30 square metres of product；Often processing is repeated 3 times, totally 147 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state), 100g/L cyazofamids suspending agent (Shanghai Sheng Nong biochemical products limited liability company) institute is bought by market
.
Disease investigation, dispenser before the onset of pepper anthracnose, dispenser 2 times are spaced 7 days, 7 days after first time medicine, second
Disease index is investigated within 7 days after dispenser respectively, calculates control effect.5 points of investigation are taken at random per cell, and 50 fruits are taken per cell,
The percentage that entire fruit area is accounted for lesion area is classified, and severity Scaling takes 0,1,3,5,7,9 totally six ranks.Point
Grade standard is as follows：
0 grade：It is disease-free；
1 grade：Scab accounts for 2% or less fruit area；
3 grades：Scab accounts for the 3%~8% of fruit area；
5 grades：Scab accounts for the 9%~15% of fruit area；
7 grades：Scab accounts for the 16%~25% of fruit area；
9 grades：Scab accounts for 25% or more of fruit area.
Drug effect computational methods：
In formula：CK1--- disease index after blank district dispenser；PT1--- disease index after chemicals treatment district dispenser；
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis：
The different embodiments of table 11 are to pepper anthracnose field control effect
Alkene oxime amine single dose is to the preventive effect of pepper anthracnose and imazalil, benzoxazole, metconazole single dose as shown in Table 11
Preventive effect is suitable, is higher than cyazofamid single dose.Have compared to single dose to the preventive effect of pepper anthracnose by each embodiment after compounding
It significantly improves, the control effect for compounding the bactericidal composition of mixture is more universal than the control effect of any one separate constituent
It is higher by 10% or more.It is bright to illustrate that alkene oxime amine and imazalil, benzoxazole, cyazofamid, metconazole compounding have pepper anthracnose
Aobvious synergistic effect.Field is estimated, and within the range of experimental dose, normal for examination chili growth, each treatment agent does not occur pair
The poisoning phenomenon of capsicum.
2.5 different embodiments prevent wheat scab field control effectiveness test
Experiment is to raise wheat 13 for examination wheat breed in the Guichi District of Chizhou City, Anhui Province villages Mei Li, preceding stubble be one season semilate rice, it is small
Wheat planting type broadcasts sowing for rotary tillage.The soil of all experimental plots, cultivation are horizontal consistent with fertilizer and water management.Experiment is set at 24
Reason, 30 square metres of plot area；Often processing is repeated 3 times, totally 72 cells, cell random alignment.
20% alkene oxime amine missible oil is provided, 60g/L metconazole aqueous emulsions by changing pesticide chemical research and development Co., Ltd in Shenyang
It is made by oneself for laboratory, 22.2% Imazalil EC (Jinan City, Shandong Province Shi Bang agrochemical Co., Ltd), 24% benzoxazole suspending agent are (beautiful
Dow AgroSciences of state) by market purchase gained.
Wheat is in flowering initial stage when experiment, and flowering accounts for about 5-10%, and dispenser 2 times is spaced 10 days, mu spouting liquid 30L.End
Incidence is managed in investigation everywhere when 22 days head blight stable diseases after secondary medicine, as unit of fringe, per the 5 points of samplings of cell diagonal line,
Every 100 fringes of investigation, look into 500 fringes altogether, count sick spike number and are classified to sick fringe, calculate preventive effect.Disease scale standard is as follows：
0 grade：It does not fall ill；
1 grade：Morbidity spikelet number accounts for 1/4 or less total spikelet number；
2 grades：Morbidity spikelet number accounts for total spikelet number 1/4~1/2；
3 grades：Morbidity spikelet number accounts for total spikelet number 1/2~3/4；
4 grades：Morbidity spikelet number accounts for 3/4 or more total spikelet number.
Drug effect computational methods：
To the other influences of crop
Whether observation crop has poisoning generation, should also record other beneficial effects to crop.
Test result and analysis：
The different embodiments of table 12 are to wheat scab field control effect
Alkene oxime amine single dose is to the preventive effect of wheat scab and imazalil, benzoxazole, metconazole single dose as shown in Table 12
Preventive effect is substantially suitable.It is all significantly improved compared to single dose to the preventive effect of wheat scab by each embodiment after compounding, it is multiple
The control effect of the bactericidal composition with mixture than the control effect of any one separate constituent be generally higher by 10% with
On.Illustrate that alkene oxime amine has apparent synergistic effect with imazalil, benzoxazole, metconazole compounding to wheat scab.Field
Range estimation, within the range of experimental dose, normal for examination wheat growth, each treatment agent does not occur the poisoning phenomenon to wheat.
It can be seen that bactericidal composition generation of the present invention has the beneficial effect that：
(1) compared with single dose, which has synergistic effect to disease, improves bactericidal effect；
(2) dosage and drug cost for lowering single dose, reduce environmental pollution and pesticide residue；
(3) composition is made of the active ingredient of different role mechanism, and action site increases, and is conducive to overcome and delay disease
The generation of bacterium drug resistance.
Above in association with illustratively illustrating present embodiments.Those skilled in the art are according to this disclosure
Content be readily apparent that, can each embodiment suitably be adjusted and be reconfigured according to actual needs, without
Spirit and scope can be detached from.The protection domain of the application is subject to following claims.
Claims (11)
1. a kind of composition pesticide, the composition pesticide is containing there are two types of active components：Active components A is alkene oxime amine, activity
Ingredient B is one or more in benzoxazole, imazalil, cyazofamid, metconazole, and active constituent B preferably is selected from metconazole, nitrile benzene
It is one or more in azoles.
2. composition pesticide according to claim 1, which is characterized in that the active components A:The weight of active constituent B
Portion rate is 1:80~80:1, preferably 1:60~60:1, preferably 1:20~20:1.
3. according to the composition pesticide described in any one of claim 1-4, which is characterized in that active components A and activity at
The 5%-81%, preferably 10%-61% for dividing the weight summation of B to account for composition gross weight.
4. composition pesticide according to any one of claim 1-3, which is characterized in that the composition pesticide is outstanding for water
Floating agent, dispersible oil-suspending agent, aqueous emulsion, microemulsion, wettable powder, suspension seed-coating agent, water dispersible granules, seed treatment can
Dispersion powder, seed treatment microcapsule suspending agent or missible oil.
5. composition pesticide according to claim 4, which is characterized in that the composition pesticide is for foliar spray, kind
Subprocessing or soil treatment.
6. the composition pesticide described in a kind of any one of claim 1-5 is used for the purposes of controlling plant diseases.
7. purposes according to claim 6, which is characterized in that the plant disease be by sac fungus, basidiomycetes, oomycetes and
Fungi Imperfecti fungi causes, preferably cucumber downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early epidemic
Disease, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape,
White rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease
Disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, silk
Smut, the late blight of potato, early blight.
8. a kind of method of controlling plant diseases, which is characterized in that by the pesticide combination described in any one of claim 1-5
Object is applied to Cereal, fruit tree, vegetables and industrial crops planting area, with controlling plant diseases.
9. according to the method described in claim 8, it is characterized in that, the plant disease be by sac fungus, basidiomycetes, oomycetes and
Fungi Imperfecti fungi causes, preferably cucumber downy mildew, powdery mildew, anthracnose, scab, tomato late blight, leaf mold, early epidemic
Disease, gray mold, western melon powdery mildew, anthracnose, blight dis-ease, droop, downy mildew of garpe, anthracnose, powdery mildew, anthrachose of grape,
White rot, gray mold, alternaria leaf spot of apple, brown spot, scab, ring spot, anthracnose, melon and pepper anthracnose, epidemic disease
Disease, flowers powdery mildew and leaf spot, wheat scab, powdery mildew and rust, rice sheath blight disease, bakanae disease, maize sheath blight, silk
Smut, the late blight of potato, early blight.
10. according to the method described in claim 9, it is characterized in that, the component of the composition pesticide be configured to preparation application,
Or the mixed application of bucket.
11. a kind of method preparing the composition pesticide as described in any one of claim 1-5, which is characterized in that described
Method is by the active components A, active constituent B and agriculturally acceptable carrier or auxiliary agent mix.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710075714.2A CN108419798A (en) | 2017-02-13 | 2017-02-13 | A kind of bactericidal composition and its application containing alkene oxime amine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710075714.2A CN108419798A (en) | 2017-02-13 | 2017-02-13 | A kind of bactericidal composition and its application containing alkene oxime amine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108419798A true CN108419798A (en) | 2018-08-21 |
Family
ID=63154912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710075714.2A Pending CN108419798A (en) | 2017-02-13 | 2017-02-13 | A kind of bactericidal composition and its application containing alkene oxime amine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108419798A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109601538A (en) * | 2018-12-10 | 2019-04-12 | 沈阳化工大学 | A kind of pesticide seed treatment agent containing fenoximamide |
| CN116391718A (en) * | 2023-03-31 | 2023-07-07 | 沈阳中化农药化工研发有限公司 | Liquid sterilization preparation containing enestroburin and application thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191670A (en) * | 1998-02-10 | 1998-09-02 | 化工部沈阳化工研究院 | Pesticide and fungicide of unsaturated oximido ethers |
| CN1596644A (en) * | 2003-09-19 | 2005-03-23 | 沈阳化工研究院 | Bacteridal composition containing alkene oxime amine and triazole kind compound |
| CN102113487A (en) * | 2010-12-30 | 2011-07-06 | 陕西美邦农药有限公司 | Bactericidal composition containing cyazofamid and methoxy acrylate compound |
| CN103371184A (en) * | 2013-06-27 | 2013-10-30 | 王学权 | Fungicidal composition containing prochloraz manganese complex |
| CN103918691A (en) * | 2013-01-12 | 2014-07-16 | 王学权 | Imazalil-containing sterilization composition |
| CN105248443A (en) * | 2014-07-18 | 2016-01-20 | 中化农化有限公司 | Pesticide composition containing fenaminstrobin, thifluzamide and prochloraz |
| CN105265446A (en) * | 2014-07-18 | 2016-01-27 | 中化农化有限公司 | Pesticide combination containing fenaminstrobin and tetraconazole |
-
2017
- 2017-02-13 CN CN201710075714.2A patent/CN108419798A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1191670A (en) * | 1998-02-10 | 1998-09-02 | 化工部沈阳化工研究院 | Pesticide and fungicide of unsaturated oximido ethers |
| CN1596644A (en) * | 2003-09-19 | 2005-03-23 | 沈阳化工研究院 | Bacteridal composition containing alkene oxime amine and triazole kind compound |
| CN102113487A (en) * | 2010-12-30 | 2011-07-06 | 陕西美邦农药有限公司 | Bactericidal composition containing cyazofamid and methoxy acrylate compound |
| CN103918691A (en) * | 2013-01-12 | 2014-07-16 | 王学权 | Imazalil-containing sterilization composition |
| CN103371184A (en) * | 2013-06-27 | 2013-10-30 | 王学权 | Fungicidal composition containing prochloraz manganese complex |
| CN105248443A (en) * | 2014-07-18 | 2016-01-20 | 中化农化有限公司 | Pesticide composition containing fenaminstrobin, thifluzamide and prochloraz |
| CN105265446A (en) * | 2014-07-18 | 2016-01-27 | 中化农化有限公司 | Pesticide combination containing fenaminstrobin and tetraconazole |
Non-Patent Citations (2)
| Title |
|---|
| 刘长令: "《世界农药大全杀菌剂卷》", 31 January 2008 * |
| 郭玉人: "《农药安全使用手册》", 30 September 2009 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109601538A (en) * | 2018-12-10 | 2019-04-12 | 沈阳化工大学 | A kind of pesticide seed treatment agent containing fenoximamide |
| CN116391718A (en) * | 2023-03-31 | 2023-07-07 | 沈阳中化农药化工研发有限公司 | Liquid sterilization preparation containing enestroburin and application thereof |
| CN116391718B (en) * | 2023-03-31 | 2024-06-11 | 沈阳中化农药化工研发有限公司 | Liquid sterilization preparation containing enestroburin and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104604938A (en) | Bactericide composition and application thereof | |
| CN106922703A (en) | A kind of bactericidal composition | |
| WO2015135422A1 (en) | Method for protecting plant against plant disease | |
| CN107549190A (en) | Seed treatment composition and its application | |
| CN105265446B (en) | A kind of composition pesticide containing alkene oxime amine and tetraconazole | |
| CN105265434B (en) | Composition pesticide containing fludioxonil | |
| CN102657184B (en) | Sterilizing composition containing phenylate diazole and thifluzamide | |
| CN102239850A (en) | Fluopicolpkd-containing agricultural bactericidal composition | |
| CN108419798A (en) | A kind of bactericidal composition and its application containing alkene oxime amine | |
| CN108419804A (en) | A kind of bactericidal composition and its application | |
| CN104542585A (en) | Fungicide composition and application thereof | |
| CN103392715A (en) | Sterilization composition containing cyprodinil and captan | |
| CN102972419B (en) | Bactericidal composition containing thifluzamide and SYT (N-methyl 2-[2-((((4-(2, 6 dichloro-phenyl)-3-butenylidene-2-yl) amino) xy) methyl)-phenyl]-2-methoxyiminoacetamide) and application thereof | |
| CN114766483B (en) | Sterilization composition containing bronopol and application thereof | |
| CN102754649B (en) | Sterilizing composition containing phenylate bi (imidazole) and epoxiconazole | |
| CN106922695A (en) | A kind of bactericidal composition | |
| CN105638697B (en) | Composition pesticide and its application containing methoxy acrylic bactericide | |
| CN107372548A (en) | Composition pesticide containing captan and fluorine azoles ring bacterium amine and application thereof | |
| CN103988843B (en) | A kind of bactericidal composition | |
| CN103392739B (en) | Sterilizing composition containing mandipropamid and copper calcium sulphate | |
| CN102986710A (en) | Bactericidal composition containing bellkute and difenoconazole and application of composition | |
| CN103348990B (en) | Bactericidal composition containing mandipropamid and captan | |
| CN103039493B (en) | Bactericidal composition containing active ingredients bellkute and triflumizole and application of bactericidal composition | |
| CN107535518A (en) | Seed treatment composition and its application | |
| CN108200909A (en) | A kind of bactericidal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180821 |