CN1055242C - Chinese medicine for curing aseptic necrosis of head of femur - Google Patents
Chinese medicine for curing aseptic necrosis of head of femur Download PDFInfo
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- 239000000203 mixture Substances 0.000 claims abstract description 5
- 241000305492 Gastrodia Species 0.000 claims abstract description 4
- 208000007875 Femur Head Necrosis Diseases 0.000 claims description 17
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Abstract
The present invention discloses a Chinese medicine medical composition for treating femoral head necrosis, which comprises Chinese angelica root, wolfberry fruits, dodder, red peony root, white peony root, tortoise plastron, pangolin, fresh fossilia ossis mastodi, fresh oyster shells, radix dipsaci from Sichuan of China, drynaria, gastrodia tuber, pawpaws, safflower, dried orange peels, earthworms, amomi compacti, acanthopanax barks, amber, phrymaceae, buck grass, rhizoma corydalis, notoginseng and red sage root. The present invention performs a favorable therapeutic function on aseptic femoral head necrosis.
Description
The present invention is a kind of Chinese medicine for the treatment of aseptic necrosis of femoral head, belongs to drug world.
Ischemic necrosis of femoral head belongs to Chinese medicine " osteomyelitis ", " rheumatism involving the bone " category, is global disease, but at country variant, its sickness rate of different regions is more or less the same, the whole world 6,000,000,000 populations, and sickness rate accounts for 0.66%.China's 1,200,000,000 populations, sickness rate accounts for 0.16%, and the patient is more with the male, seriously affects people's physical and mental health, affects development of productivity, brings immeasurable loss to national economy.Up to the present, the method for treatment ischemic necrosis of femoral head is a lot, as methods such as the medicine injection of Chinese medicine, acupuncture, physical therapy, doctor trained in Western medicine, operations.But weak point is in various degree all arranged, and the operation method of doctor trained in Western medicine is more, and the patient be difficult for to accept, in the recent period can only alleviating pain, and long-term effect is not ideal, and operation wound is bigger, costs an arm and a leg.Post-operative complication is more.Therefore, seek easy, quick-acting, a no pain, promptly the economy Therapeutic Method of material benefit again is still the problem of current medical circle research.In order to remove the misery of extensive patients as early as possible, satisfy femur head necrosis patient's needs, we select a topic and have developed that effective, curative effect is fast, short treating period, cure rate height, and relapse rate is low, the medicine of the treatment ischemic necrosis of femoral head of low modest, the social and economic benefits and good of price.
Therefore, the object of the invention provides a kind of medicine of effective treatment femur head necrosis.
The inventor is on the basis of secret prescription handed down in the family from generation to generation, and through the clinical practice in surplus 40 years, the sanction checking was changed in repeated screening, has been developed into medicine of the present invention.
The basic composition of medicine of the present invention is active ingredient (by weight) with following pharmaceutical composition:
Radix Angelicae Sinensis: 50-70 part Fructus Lycii: 40-60 part field dobber: 20-40 part
Radix Paeoniae Rubra: 20-40 part Radix Paeoniae Alba: 50-70 part Carapax et Plastrum Testudinis: 30-50 part
Squama Manis: 30-50 part Os Draconis: 50-70 part Concha Ostreae: 50-70 part
Radix Dipsaci: 30-50 part Rhizoma Drynariae: 30-50 part Rhizoma Gastrodiae: 30-50 part
Fructus Chaenomelis: 40-60 part Flos Carthami: 20-40 part Radix Salviae Miltiorrhizae: 50-70 part
Pheretima: 30-50 part Fructus Amomi Rotundus: 30-50 part Pericarpium Citri Reticulatae: 30-50 part
Cortex Acanthopancis: 30-50 part succinum: 20-40 part Herba speranskiae tuberculatae: 30-50 part
Herba Lycopodii: 30-50 part Rhizoma Corydalis: 30-50 part Radix Notoginseng: 30-50 part
The preferred weight proportioning of aforementioned pharmaceutical compositions each component is:
Radix Angelicae Sinensis: 60 gram Fructus Lycii: 50 gram field dobbers: 30 gram Radix Paeoniae Rubra: 30 grams
The Radix Paeoniae Alba: 60 gram Carapax et Plastrum Testudiniss: 40 gram Squama Maniss: 40 gram Os Draconis: 60 grams
Concha Ostreae: 60 gram Radix Dipsaci: 40 gram Rhizoma Drynariae: 40 gram Rhizoma Gastrodiaes: 40 grams
Fructus Chaenomelis: 50 gram Flos Carthamis: 30 gram Radix Salviae Miltiorrhizaes: 60 gram Pheretimas: 40 grams
Fructus Amomi Rotundus: 40 gram Pericarpium Citri Reticulataes: 40 gram Cortex Acanthopanciss: 40 gram succinums: 30 grams
Herba speranskiae tuberculatae: 40 gram Herba Lycopodiis: 40 gram Rhizoma Corydalis: 40 gram Radix Notoginseng: 40 grams
Aforementioned pharmaceutical compositions of the present invention according to the process of Chinese medicine preparation of routine, can prepare any medicament commonly used, as pill, powder, tablet, oral liquid etc.
The preparation method of bolus of drug of the present invention is:
Choose medical material according to said ratio, oven dry is pulverized, and making pellets by mixing medical powder with honey, every ball weigh 11 grams.
Medicine of the present invention has the effect of invigorating the spleen and regulating the stomach, compensate qi and blood, life essence-filling, marrow-benefitting, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, and femur head necrosis is had therapeutical effect preferably.Clinical total effective rate reaches 97%, and cure rate reaches 82%, and the clinical efficacy drug safety is subjected to the extensive patients favorable comment deeply.
Experimental example 1
From in January, 91, we are in strict accordance with the unified diagnosis and the criterion of therapeutical effect of national ischemic necrosis of femoral head, adopt the method for completely random contrast, patient to 260 routine femur head necrosiss and each position osteonecrosis has carried out observation of curative effect, wherein there are 60 routine femur head necrosis patients to make operation, decompression operation 32 examples, bone grafting operation 26 examples at certain large hospital, femoral head resection operation 1 example is done femoral head and is rotated 1 example.Do once 40 examples of operation, do 18 examples of two operations, do 2 examples of three operations.Do not treat femur head necrosis curative effect medicine because of modern medicine, so have only operation, long-term effect is very undesirable, and the treatment of seeking medical advice is satisfied in small number of patients postoperative long term disability bed, and 260 examples are pressed: marcus by stages, I-II phases 10 example, III phase-IV phases 200 example; VVI phases 50 example, predetermined treatment duration obtains satisfied effect by stages.Now be summarized as follows;
One, clinical data
1, case is selected
Accept for medical treatment among the 1200 routine patients, select 260 examples, wherein outpatient service 200 examples.60 examples of being in hospital, the classical symptom of femur head necrosis and each position osteonecrosis, sign, before the treatment all through X line pathological staging and main indications, CT examination, observe the size of sequestrum piece from cross-section layering, nuclear magnetic resonance, MRL checks confirmation, the size of femur head necrosis and each position osteonecrosis, the osteonecrosis district is out of shape and subsides, and the disease of arthrostenosis is shone.According to tcm syndrome differentiation and typing, deficiency of kidney-QI 90 examples, yang deficiency of spleen and stomache 150 examples; Caused by hepatic stagnation qi stagnation 9 examples; Tire natural endowment marrow deficiency will be lost dysplasia 11 examples of nourishing one's nature the day after tomorrow.
2, physical data
Case is selected 260 examples, wherein: male 242 examples, women 18 examples, age (1-12 year) 11 examples; (13-20 year) 19 examples: (21-40 year) 180 examples; (41-60 year) 30 examples; 20 examples more than 60 years old, the course of disease is the longest 14 years, and is the shortest 8 months, and ill 1 year with interior 70 examples; (1-6) year 150 examples; (6-10) year 30 examples; 10 examples more than 10 years.
Two, Therapeutic Method:
1, outpatient service, the femur head necrosis and the position osteonecrosis patient that are in hospital, dialectical the executing of Chinese medicine controlled, the detailed survey cause of disease, pathological change, reasonable change, rational use of drug, pill of the present invention (specification: every ball 10g) for oral administration, make by oneself personal by the Taikang County Zhang Ji Drug Manufacturing Room of commune hospital, usage every day three times, each ball, warm boiled water.Three months is a course of treatment.Two recoveries from illness course of treatment of I-II phase, III-IV phase 3-4 the recovery from illness course of treatment, five of V-VI (later stage) are almost recovered or thoroughly recovery from illness the course of treatment, effective percentage 97%, cure rate 82%.
Three, efficacy analysis
1, cure: pain disappears around the hip joint, and function is improved normal, and walk not have and walk lamely, the prompting of 4 words test (bend, stretch, open up, revolve) (one) .X radiograph, the femur head necrosis district all absorbs, and area of new bone forms.The perichondrium tissue repair, 2 kilometers of walkings are asymptomatic, participate in manual labor and work.(curing 10-20) no recurrent cases record in surplus year.
2, produce effects: pain disappears, and function is improved, and does not have limping on foot substantially, and 4 words test (one) osteonecrosis district absorbs, and area of new bone forms, the perichondrium tissue repair, and 2 kilometers buttocks acid precipitation of walking do not have painful.
3, take a turn for the better: minority femur head necrosis patient, curative effect of medication still can.Pain disappears substantially, and function is obviously improved, rare limping; Osteonecrosis is most of to be absorbed, but does not accomplish the end in view by absorbing the expected time of arrival.Extend the period of treatment slightly and can fully recover.
4, curative effect of medication is not obvious, can control the development of osteonecrosis district, and symptom can be alleviated, and curative effect has improvement, but not obvious, heavy when light during the rheumatic and rheumatoid type, but the femur head necrosis district absorbs by the pre-treatment phase, and area of new bone forms, all still can, it is slower that function is improved, extended treatment expected time of arrival.
Four, therapeutic outcome
By the predetermined treatment duration efficacy result
| Several planned number order orders | The example number | Cure routine number | Cure rate | Show the rate rate | Obvious effective rate | Improvement rate | Improvement rate | The not obvious prolongation of effect of drugs digit rate expected time of arrival % |
| Chinese medicine expectant treatment group | 200 | 160 | 80％ | 20 | 10％ | 12 | 6％ | 8 4％ |
| Postoperative prescription on individual diagnosis group | 60 | 42 | 70％ | 8 | 5 | 5 |
See and treat patients certain hospital perform an operation the back efficacy result
| Several planned number order orders | The example number | Alleviate routine number | Wherein | Operation back bed 1-4 | |
| 6 months | 1 year | ||||
| Surgical effect | 60 | 42 | 30 | 12 | 18 |
Embodiment prescription: Radix Angelicae Sinensis: 60 gram Fructus Lycii: 50 gram field dobbers: 30 gram Radix Paeoniae Rubra: the 30 gram Radix Paeoniae Albas: 60 gram Carapax et Plastrum Testudiniss: 40 gram Squama Maniss: 40 gram Os Draconis: 60 gram Concha Ostreae: 60 gram Radix Dipsaci: 40 gram Rhizoma Drynariae: 40 gram Rhizoma Gastrodiaes: 40 gram Fructus Chaenomeliss: 50 gram Flos Carthamis: 30 gram Radix Salviae Miltiorrhizaes: 60 gram Pheretimas: 40 gram Fructus Amomi Rotundus: 40 gram Pericarpium Citri Reticulataes: 40 gram Cortex Acanthopanciss: 40 gram succinums: 30 gram Herba speranskiae tuberculataes: 40 gram Herba Lycopodiis: 40 gram Rhizoma Corydalis: 40 gram Radix Notoginseng: 40 restraint methods: said medicine is dried, pulverize, cross 100 mesh sieves, making pellets by mixing medical powder with honey, every ball weigh 11 grams.
Claims (2)
1, a kind of Chinese medicine composition for the treatment of femur head necrosis is characterized in that said composition made by following raw materials according:
Radix Angelicae Sinensis: 50-70 part Fructus Lycii: 40-60 part field dobber: 20-40 part
Radix Paeoniae Rubra: 20-40 part Radix Paeoniae Alba: 50-70 part Carapax et Plastrum Testudinis: 30-50 part
Squama Manis: 30-50 part Os Draconis: 50-70 part Concha Ostreae: 50-70 part
Radix Dipsaci: 30-50 part Rhizoma Drynariae: 30-50 part Rhizoma Gastrodiae: 30-50 part
Fructus Chaenomelis: 40-60 part Flos Carthami: 20-40 part Radix Salviae Miltiorrhizae: 50-70 part
Pheretima: 30-50 part Fructus Amomi Rotundus: 30-50 part Pericarpium Citri Reticulatae: 30-50 part
Cortex Acanthopancis: 30-50 part succinum: 20-40 part Herba speranskiae tuberculatae: 30-50 part
Herba Lycopodii: 30-50 part Rhizoma Corydalis: 30-50 part Radix Notoginseng: 30-50 part.
2,, it is characterized in that the each component weight proportion is according to the Chinese medicine composition of claim 1:
Radix Angelicae Sinensis: 60 gram Fructus Lycii: 50 gram field dobbers: 30 gram Radix Paeoniae Rubra: 30 grams
The Radix Paeoniae Alba: 60 gram Carapax et Plastrum Testudiniss: 40 gram Squama Maniss: 40 gram Os Draconis: 60 grams
Concha Ostreae: 60 gram Radix Dipsaci: 40 gram Rhizoma Drynariae: 40 gram Rhizoma Gastrodiaes: 40 grams
Fructus Chaenomelis: 50 gram Flos Carthamis: 30 gram Radix Salviae Miltiorrhizaes: 60 gram Pheretimas: 40 grams
Fructus Amomi Rotundus: 40 gram Pericarpium Citri Reticulataes: 40 gram Cortex Acanthopanciss: 40 gram succinums: 30 grams
Herba speranskiae tuberculatae: 40 gram Herba Lycopodiis: 40 gram Rhizoma Corydalis: 40 gram Radix Notoginseng: 40 grams.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98102686A CN1055242C (en) | 1998-06-30 | 1998-06-30 | Chinese medicine for curing aseptic necrosis of head of femur |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98102686A CN1055242C (en) | 1998-06-30 | 1998-06-30 | Chinese medicine for curing aseptic necrosis of head of femur |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1203098A CN1203098A (en) | 1998-12-30 |
| CN1055242C true CN1055242C (en) | 2000-08-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98102686A Expired - Fee Related CN1055242C (en) | 1998-06-30 | 1998-06-30 | Chinese medicine for curing aseptic necrosis of head of femur |
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| Country | Link |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100350964C (en) * | 2005-04-15 | 2007-11-28 | 杜银华 | Medicine for treating femoral head necrosis and its preparation method |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076617C (en) * | 1999-06-16 | 2001-12-26 | 王松彪 | Medicine specially for treating caput femoris necrosis, and method for preparing same |
| CN101204531B (en) * | 2007-12-19 | 2010-05-19 | 钱培森 | Medicament composite for ANFH |
| CN104127847A (en) * | 2014-08-07 | 2014-11-05 | 殷波 | Traditional Chinese medicine composition for treating femoral head necrosis |
-
1998
- 1998-06-30 CN CN98102686A patent/CN1055242C/en not_active Expired - Fee Related
Non-Patent Citations (3)
| Title |
|---|
| 《中国骨伤》5(1) 1992.1.1 罗元方等，中医治疗股骨头骨软骨炎14例疗效分析 * |
| 《山东中医学院学报》17(2) 1993.1.1 梁洪举等，中药治疗364例成人股骨头无菌性坏死 * |
| 《山东中医学院学报》17(2) 1993.1.1 梁洪举等，中药治疗364例成人股骨头无菌性坏死;《中国骨伤》5(1) 1992.1.1 罗元方等，中医治疗股骨头骨软骨炎14例疗效分析 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100350964C (en) * | 2005-04-15 | 2007-11-28 | 杜银华 | Medicine for treating femoral head necrosis and its preparation method |
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| CN1203098A (en) | 1998-12-30 |
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