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CN105343712A - Traditional Chinese medicine composition for treating chronic pharyngitis - Google Patents

Traditional Chinese medicine composition for treating chronic pharyngitis Download PDF

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CN105343712A
CN105343712A CN201510821982.5A CN201510821982A CN105343712A CN 105343712 A CN105343712 A CN 105343712A CN 201510821982 A CN201510821982 A CN 201510821982A CN 105343712 A CN105343712 A CN 105343712A
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chinese medicine
medicine composition
chronic pharyngitis
traditional chinese
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CN105343712B (en
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江海艳
顾敬敏
张岚
刘继民
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/902Sparganiaceae (Bur-reed family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/88Liliopsida (monocotyledons)
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Abstract

The invention relates to a traditional Chinese medicine composition for treating chronic pharyngitis. The traditional Chinese medicine composition comprises the following bulk drugs by weight: 20 to 30 parts of Radix Astragali, 6 to 10 parts of rhizoma sparganii, 10 to 15 parts of Chinese angelica, 15 to 20 parts of oroxylum indicum, 10 to 15 parts of radix scrophulariae, 6 to 10 parts of muscardine silkworm, 10 to 15 parts of Terminalia, 10 to 15 parts of dark plum 10 to 15 parts of licorice and 20 to 30 parts of fructus forsythia. In 66 cases of chronic pharyngitis treated with the traditional Chinese medicine composition, 43 cases (65%) are cured, the traditional Chinese medicine composition takes obvious effect in 12 cases (18%) and is effective in 8 cases (12%) and ineffective in 3 cases (5%), so the total effective rate of the traditional Chinese medicine composition is 95%. For a chronic pharyngitis patient with an itching throat, the component divaricata saposhnikovia root can be added; for a chronic pharyngitis patient with a sore throat, the components consisting of puffball fruiting body and arctium fruit can be added; and for a chronic pharyngitis patient with liver depression transforming into fire, the components consisting of curcuma tuber and Sichuan Chinaberry fruit can be added. The traditional Chinese medicine composition has obvious curative effect when applied to treatment of chronic pharyngitis and can be widely popularized and applied.

Description

A kind of Chinese medicine composition for the treatment of chronic pharyngitis
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine composition for the treatment of chronic pharyngitis.
Background technology
Chronic pharyngitis refers to pharyngeal mucosa chronic inflammatory disease, and how because acute pharyngitis recurrent exerbation or treatment are thorough, and adjacent organs focus stimulates such as sinusitis, tonsillitis, nasopharyngitis, tracheitis etc. cause, be more common in adult, the course of disease is long, and symptom is obstinate, not easily cures.Most patients has various pharyngeal sense of discomfort, as foreign body sensation, burning sensation, dry sensation, gargalesthesia or mild pain, rises morning and occurs frequent irritable cough, nausea and vomiting.Chronic pharyngitis recurrent exerbation, delay is difficult, often causes extreme influence to minimal invasive treatment and work.And western medicine is often not fully up to expectations, in doctor trained in Western medicine, commonly uses the treatment meanss such as local buccal tablet, antibiotic, Neulized inhalation and removing toxic substances, after long-time treatment, there will be drug resistance.On the contrary, Chinese medicine prescription in treatment considers that method for the treatment of pursues treating both the principal and secondary aspects of a disease, and side effect is low, can improve clinical efficacy comprehensively.Therefore how to develop one to may be used for treating chronic pharyngitis, and curative effect Chinese medicine composition that is obvious, that can extensively promote the use of is most important.
Summary of the invention
The present invention will solve technical problem of the prior art, provide a kind of curative effect obviously, can extensively promote the use of, the Chinese medicine composition for the treatment of chronic pharyngitis.
In order to solve the problems of the technologies described above, technical scheme of the present invention is specific as follows:
Treat a Chinese medicine composition for chronic pharyngitis, comprise the crude drug composition of following weight portion:
The Radix Astragali 20 ~ 30 parts, Rhizoma Sparganii 6 ~ 10 parts, Radix Angelicae Sinensis 10 ~ 15 parts, Semen Oroxyli 15 ~ 20 parts, Radix Scrophulariae 10 ~ 15 parts, Bombyx Batryticatus 6 ~ 10 parts, Fructus Chebulae 10 ~ 15 parts, Fructus Mume 10 ~ 15 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 ~ 30 parts.
In technique scheme, in described Chinese medicine composition, the weight portion of each crude drug is:
The Radix Astragali 30 parts, Rhizoma Sparganii 10 parts, Radix Angelicae Sinensis 10 parts, Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Bombyx Batryticatus 10 parts, Fructus Chebulae 10 parts, Fructus Mume 10 parts, 10 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 parts.
In technique scheme, described Chinese medicine composition also comprises 10 ~ 15 parts of Radix Saposhnikoviaes.
In technique scheme, described Chinese medicine composition also comprises 6 ~ 10 parts of Lasiosphaera Seu Calvatia, 10 ~ 15 parts of Fructus Arctiis.
In technique scheme, described Chinese medicine composition also comprises 15 ~ 20 portions of Radix Curcumaes, 10 ~ 15 parts of Fructus Toosendans.
In technique scheme, described Chinese medicine composition is by obtaining each crude drug decocting extracting juice.
The invention has the beneficial effects as follows:
The Chinese medicine composition for the treatment of chronic pharyngitis provided by the invention, main formula comprises the Radix Astragali, Rhizoma Sparganii, Radix Angelicae Sinensis, Semen Oroxyli, Radix Scrophulariae, Bombyx Batryticatus, Fructus Chebulae, Fructus Mume, Radix Glycyrrhizae, Fructus Forsythiae, be used for the treatment of chronic pharyngitis curative effect obvious, and this medicine extensively can be promoted the use of.If itching throat person, Radix Saposhnikoviae component can also be added; If pharyngalgia person, Lasiosphaera Seu Calvatia and Fructus Arctii component can also be added; If pathogenic fire derived from stagnation of liver-QI person, Radix Curcumae and Fructus Toosendan can also be added.
The sweet temperature of the Radix Astragali in described Chinese medicine composition, air making-up and spleen enlivening lung benefiting; Radix Angelicae Sinensis Gan Xinwen, nourshing blood and promoting blood circulation, QI replenishing and blood harmonizing promoting the circulation of blood; Rhizoma Sparganii is arduous flat, returns liver spleen channel, blood circulation promoting and blood stasis dispelling, then controls gas from gas medicine, then control blood from blood medicine; Semen Oroxyli, Radix Scrophulariae sweetness and bitterness, be slightly cold, removing heat from blood sore-throat relieving; Fructus Mume, Fructus Chebulae are promoted the production of body fluid and are moistened dryness and relieve cough, and strengthen the merit of sore-throat relieving; The dissipating phlegm and resolving masses of Bombyx Batryticatus endogenous wind stopping; Fructus Forsythiae detoxicating and resolving stagnation of pathogens; Radix Glycyrrhizae heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.
In the 66 routine patients with chronic pharyngitis using Chinese medicine composition of the present invention to be used for the treatment of, cure 43 examples (65%), effective 12 examples (18%), effective 8 examples (12%), invalid 3 examples (5%), total effective rate is 95%.Absolutely prove that Chinese medicine composition of the present invention is used for the treatment of chronic pharyngitis curative effect obvious, extensively can promote the use of, there is good application prospect.
Detailed description of the invention
Below in conjunction with clinical trial data, the present invention is described in detail.
1 clinical data
1.1 diagnostic criteria
With reference to " ENT & HN Surgery Dept. " six editions formulation: (1) medical history: have acute pharyngitis recurrent exerbation medical history, the course of disease more than 3 months more; (2) symptom: pharyngeal have sense of discomfort, or pain or itch or dry sensation, burning sensation, foreign body sensation etc., time light time heavy, time have cough, easy expectoration is sticky expectorant on a small quantity, and rising morning easily feels sick feels sick; (3) sign: pharyngeal mucosa is congested, in kermesinus, or dendroid is congested; Retropharyneal folliculosis, or lateral pharyngeal band enlargement; Pharyngeal mucous membrane hypertrophy is plump, or drying, atrophy, thinning, has secretions to adhere to.The each above-mentioned symptom of tool and more than 1 or 1 symptom, namely diagnosable.
1.2 physical data
66 examples are clinic case, and this organizes in 66 examples, man 33 example, female 33 example; 20 ~ 58 years old age; The course of disease 3 months ~ 10 years, all has the itching throat of recurrent exerbation, pharyngalgia, dry pharynx or foreign body sensation, all meets the diagnostic criteria of chronic pharyngitis.
1.3 curative effect determinate standard
With reference to " traditional Chinese ear nose aditus laryngis tooth medical diagnosis on disease criterion of therapeutical effect " that TCM E.N.T. Dept. the 4th academic conference is formulated, cure: in 10 days, symptom alleviates, in 3 months, Clinical symptom and sign disappears.Effective: in two weeks, symptom alleviates, in 3 months, Clinical symptom and sign disappears.Effective: in two weeks, symptom alleviates, in 3 months, clinical symptoms and part sign disappear substantially.Invalid: after medication, symptom slightly alleviates, and sign is not improved.
2 Therapeutic Method
The Chinese medicine composition for the treatment of chronic pharyngitis: the Radix Astragali 30 parts, Rhizoma Sparganii 10 parts, Radix Angelicae Sinensis 10 parts, Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Bombyx Batryticatus 10 parts, Fructus Chebulae 10 parts, Fructus Mume 10 parts, 10 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 parts; If itching throat person, add Radix Saposhnikoviae 10 parts; If pharyngalgia person, add Lasiosphaera Seu Calvatia 6 parts, Fructus Arctii 10 parts; Pathogenic fire derived from stagnation of liver-QI person adds Radix Curcumae 15 parts, Fructus Toosendan 10 parts.Above crude drug decocting extracting juice 300ml, point 150ml day twice is oral.Crude drug is provided by The Affiliated Hospital to Changchun University of Chinese Medicine two rooms of boiling medicine.Within 7 days, be 1 course for the treatment of, totally 2 courses for the treatment of.
3 results
This is organized in 66 examples and cures 43 examples (65%), effective 12 examples (18%), effective 8 examples (12%), and invalid 3 examples (5%), total effective rate is 95%.
4 discuss
Chronic pharyngitis is mainly due to internal organs virtual loss, and yin and yang imbalance, the deficiency of vital energy can not handsome blood, and the blood stasis of blood is stagnant, ties caused by the throat, curative effect achieves satisfied effect.Primary disease take void as this, and the domination of pathogen is mark, is being invaded by exogenous pathogen at the beginning of the cause of disease, mention in " Plain Questions comments pyretography " " gathering of heresy; its gas must be empty ", deficiency of vital energy disharmony of nutrient QI with defensive QI, reaches outside evil Yu Buneng, pent-up is numbness in pharynx, the cloudy blood of of a specified duration then trauma, pharynx mistake makes moist, and void for a long time must the stasis of blood, stagnation of QI and blood, fights to tie and causes a disease in pharynx.The author, in conjunction with meridians, thinks the prolonged illness network stasis of blood, and lung meridian, kidney meridian, liver channel of foot-Jueyin, the stomach channel of foot-Yang-ming all cross throat, and it be the door of lung, lung being a delicate viscus, and all kinds of diseases and ailments are attacked, for a long time the then network stasis of blood, and gas be positive, and blood is the moon, and blood stasis due to qi deficiency is tied in throat.The sweet temperature of the Radix Astragali, air making-up and spleen enlivening lung benefiting; Radix Angelicae Sinensis Gan Xinwen, nourshing blood and promoting blood circulation, QI replenishing and blood harmonizing promoting the circulation of blood; Rhizoma Sparganii is arduous flat, returns liver spleen channel, blood circulation promoting and blood stasis dispelling, then controls gas from gas medicine, then control blood from blood medicine; Semen Oroxyli, Radix Scrophulariae sweetness and bitterness, be slightly cold, removing heat from blood sore-throat relieving; Fructus Mume, Fructus Chebulae are promoted the production of body fluid and are moistened dryness and relieve cough, and strengthen the merit of sore-throat relieving; The dissipating phlegm and resolving masses of Bombyx Batryticatus endogenous wind stopping; Fructus Forsythiae detoxicating and resolving stagnation of pathogens; Radix Glycyrrhizae heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.In sum, apply traditional Chinese medicine composition for treating chronic pharyngitis curative effect of the present invention obvious, can extensively promote the use of.
In other detailed description of the invention of the present invention, the weight portion of each crude drug of the Chinese medicine composition of the treatment chronic pharyngitis of the present invention that test group adopts can also be: the Radix Astragali 20 ~ 30 parts, Rhizoma Sparganii 6 ~ 10 parts, Radix Angelicae Sinensis 10 ~ 15 parts, Semen Oroxyli 15 ~ 20 parts, Radix Scrophulariae 10 ~ 15 parts, Bombyx Batryticatus 6 ~ 10 parts, Fructus Chebulae 10 ~ 15 parts, Fructus Mume 10 ~ 15 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 ~ 30 parts be within the scope of this, other numerical value different from above-mentioned detailed description of the invention.The Chinese medicine composition of the treatment chronic pharyngitis of the present invention made, obvious to the therapeutic effect of patients with chronic pharyngitis equally, repeat no more here.
Obviously, above-described embodiment is only for clearly example being described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of extending out or variation be still among the protection domain of the invention.

Claims (6)

1. treat a Chinese medicine composition for chronic pharyngitis, it is characterized in that, comprise the crude drug composition of following weight portion:
The Radix Astragali 20 ~ 30 parts, Rhizoma Sparganii 6 ~ 10 parts, Radix Angelicae Sinensis 10 ~ 15 parts, Semen Oroxyli 15 ~ 20 parts, Radix Scrophulariae 10 ~ 15 parts, Bombyx Batryticatus 6 ~ 10 parts, Fructus Chebulae 10 ~ 15 parts, Fructus Mume 10 ~ 15 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 ~ 30 parts.
2. Chinese medicine composition according to claim 1, is characterized in that, in described Chinese medicine composition, the weight portion of each crude drug is:
The Radix Astragali 30 parts, Rhizoma Sparganii 10 parts, Radix Angelicae Sinensis 10 parts, Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Bombyx Batryticatus 10 parts, Fructus Chebulae 10 parts, Fructus Mume 10 parts, 10 parts, Radix Glycyrrhizae, Fructus Forsythiae 20 parts.
3. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition also comprises 10 ~ 15 parts of Radix Saposhnikoviaes.
4. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition also comprises 6 ~ 10 parts of Lasiosphaera Seu Calvatia, 10 ~ 15 parts of Fructus Arctiis.
5. Chinese medicine composition according to claim 1, is characterized in that, described Chinese medicine composition also comprises 15 ~ 20 portions of Radix Curcumaes, 10 ~ 15 parts of Fructus Toosendans.
6. the Chinese medicine composition according to claim 1-5 any one, is characterized in that, described Chinese medicine composition is by obtaining each crude drug decocting extracting juice.
CN201510821982.5A 2015-11-24 2015-11-24 A kind of Chinese medicine composition for treating chronic pharyngitis Expired - Fee Related CN105343712B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421335A (en) * 2016-08-30 2017-02-22 张诏 Compound medicine for treating chronic pharyngitis
CN114949147A (en) * 2022-06-20 2022-08-30 河南中医药大学第一附属医院 A traditional Chinese medicine composition for treating chronic pharyngitis, its preparation method and application

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Publication number Priority date Publication date Assignee Title
CN101869658A (en) * 2010-06-02 2010-10-27 苏店第二卫生所 Chinese medicinal infusion tea for treating chronic pharyngitis and preparation method thereof
CN103611005A (en) * 2013-12-08 2014-03-05 朱英 Medicine for treating chronic pharyngitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101869658A (en) * 2010-06-02 2010-10-27 苏店第二卫生所 Chinese medicinal infusion tea for treating chronic pharyngitis and preparation method thereof
CN103611005A (en) * 2013-12-08 2014-03-05 朱英 Medicine for treating chronic pharyngitis and preparation method thereof

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Title
刘 洁等: "常克主任医师治疗慢性咽炎经验", 《广西中医药》 *
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421335A (en) * 2016-08-30 2017-02-22 张诏 Compound medicine for treating chronic pharyngitis
CN114949147A (en) * 2022-06-20 2022-08-30 河南中医药大学第一附属医院 A traditional Chinese medicine composition for treating chronic pharyngitis, its preparation method and application
CN114949147B (en) * 2022-06-20 2023-11-14 河南中医药大学第一附属医院 A traditional Chinese medicine composition for treating chronic pharyngitis, its preparation method and application

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