CN105147591A - Anti-wrinkle face cream and preparation method thereof - Google Patents
Anti-wrinkle face cream and preparation method thereof Download PDFInfo
- Publication number
- CN105147591A CN105147591A CN201510675219.6A CN201510675219A CN105147591A CN 105147591 A CN105147591 A CN 105147591A CN 201510675219 A CN201510675219 A CN 201510675219A CN 105147591 A CN105147591 A CN 105147591A
- Authority
- CN
- China
- Prior art keywords
- extract
- crease
- facial cream
- skin
- elite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006071 cream Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 230000001153 anti-wrinkle effect Effects 0.000 title abstract description 13
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 27
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 16
- -1 polyglycerol-10 Chemical compound 0.000 claims abstract description 12
- 241000222336 Ganoderma Species 0.000 claims abstract description 11
- 235000020710 ginseng extract Nutrition 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 10
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 9
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229920006322 acrylamide copolymer Polymers 0.000 claims abstract description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 9
- 150000002148 esters Chemical class 0.000 claims abstract description 9
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 claims abstract description 9
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims abstract description 9
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 9
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims abstract description 9
- 239000004926 polymethyl methacrylate Substances 0.000 claims abstract description 9
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims abstract description 9
- 230000001815 facial effect Effects 0.000 claims description 51
- 239000000463 material Substances 0.000 claims description 11
- 241000512259 Ascophyllum nodosum Species 0.000 claims description 10
- 241000257468 Asterias amurensis Species 0.000 claims description 10
- 241000186660 Lactobacillus Species 0.000 claims description 10
- 241000220225 Malus Species 0.000 claims description 10
- 244000294611 Punica granatum Species 0.000 claims description 10
- 235000014360 Punica granatum Nutrition 0.000 claims description 10
- 235000021016 apples Nutrition 0.000 claims description 10
- 229940039696 lactobacillus Drugs 0.000 claims description 10
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 9
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 9
- 230000002421 anti-septic effect Effects 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 9
- IKQJSIJZUBAGNX-UHFFFAOYSA-N 6-bromo-3-(5-chloro-2-ethylsulfonylanilino)-7-[(4-pentan-3-ylpiperazin-1-yl)methyl]quinazolin-4-one Chemical compound BrC=1C=C2C(N(C=NC2=CC=1CN1CCN(CC1)C(CC)CC)NC1=C(C=CC(=C1)Cl)S(=O)(=O)CC)=O IKQJSIJZUBAGNX-UHFFFAOYSA-N 0.000 claims description 8
- VTNUICGUQVGYQL-UHFFFAOYSA-N N(=O)OCCCCCCCC.C(CCCCCCCC)(=O)O Chemical compound N(=O)OCCCCCCCC.C(CCCCCCCC)(=O)O VTNUICGUQVGYQL-UHFFFAOYSA-N 0.000 claims description 8
- 229940081733 cetearyl alcohol Drugs 0.000 claims description 8
- DHHFDKNIEVKVKS-FMOSSLLZSA-N Betanin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC(C[C@H]2C([O-])=O)=C1[N+]2=C\C=C\1C=C(C(O)=O)N[C@H](C(O)=O)C/1 DHHFDKNIEVKVKS-FMOSSLLZSA-N 0.000 claims description 7
- DHHFDKNIEVKVKS-MVUYWVKGSA-N Betanin Natural products O=C(O)[C@@H]1NC(C(=O)O)=C/C(=C\C=[N+]/2\[C@@H](C(=O)[O-])Cc3c\2cc(O)c(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)c3)/C1 DHHFDKNIEVKVKS-MVUYWVKGSA-N 0.000 claims description 7
- 229920002125 Sokalan® Polymers 0.000 claims description 7
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 7
- 239000001654 beetroot red Substances 0.000 claims description 7
- 235000012677 beetroot red Nutrition 0.000 claims description 7
- 235000002185 betanin Nutrition 0.000 claims description 7
- 229960001631 carbomer Drugs 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 7
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 7
- 229960001295 tocopherol Drugs 0.000 claims description 7
- 229930003799 tocopherol Natural products 0.000 claims description 7
- 235000010384 tocopherol Nutrition 0.000 claims description 7
- 239000011732 tocopherol Substances 0.000 claims description 7
- 239000000230 xanthan gum Substances 0.000 claims description 7
- 235000010493 xanthan gum Nutrition 0.000 claims description 7
- 229920001285 xanthan gum Polymers 0.000 claims description 7
- 229940082509 xanthan gum Drugs 0.000 claims description 7
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 7
- 230000001804 emulsifying effect Effects 0.000 claims description 6
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical group COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 4
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 4
- 229960003415 propylparaben Drugs 0.000 claims description 4
- 239000008346 aqueous phase Substances 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000012071 phase Substances 0.000 claims description 3
- 238000005070 sampling Methods 0.000 claims description 3
- 230000037303 wrinkles Effects 0.000 abstract description 30
- 239000002537 cosmetic Substances 0.000 abstract description 9
- 230000009759 skin aging Effects 0.000 abstract description 6
- 230000008439 repair process Effects 0.000 abstract description 5
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- LCVHZNSIAYNAGX-UHFFFAOYSA-N 2-ethylhexyl 3,5,5-trimethylhexanoate Chemical compound CCCCC(CC)COC(=O)CC(C)CC(C)(C)C LCVHZNSIAYNAGX-UHFFFAOYSA-N 0.000 abstract 1
- 241000258957 Asteroidea Species 0.000 abstract 1
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 1
- 241000195585 Chlamydomonas Species 0.000 abstract 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 abstract 1
- 244000025272 Persea americana Species 0.000 abstract 1
- 235000008673 Persea americana Nutrition 0.000 abstract 1
- 229940114077 acrylic acid Drugs 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 235000014121 butter Nutrition 0.000 abstract 1
- 229940112261 ceteareth-2 Drugs 0.000 abstract 1
- 229940082500 cetostearyl alcohol Drugs 0.000 abstract 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 abstract 1
- 229940100549 ethylhexyl isononanoate Drugs 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 239000011435 rock Substances 0.000 abstract 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 54
- 238000012360 testing method Methods 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 7
- 230000037394 skin elasticity Effects 0.000 description 6
- 230000008929 regeneration Effects 0.000 description 5
- 238000011069 regeneration method Methods 0.000 description 5
- 102000008186 Collagen Human genes 0.000 description 4
- 108010035532 Collagen Proteins 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 150000003254 radicals Chemical class 0.000 description 4
- 206010048768 Dermatosis Diseases 0.000 description 3
- 206010020751 Hypersensitivity Diseases 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 230000007815 allergy Effects 0.000 description 3
- 210000001061 forehead Anatomy 0.000 description 3
- 230000003862 health status Effects 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 208000017520 skin disease Diseases 0.000 description 3
- 206010003694 Atrophy Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 229920002683 Glycosaminoglycan Polymers 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 206010048222 Xerosis Diseases 0.000 description 2
- 230000037444 atrophy Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 239000007933 dermal patch Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000002932 luster Substances 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 150000008442 polyphenolic compounds Chemical class 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001835 salubrious effect Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 210000001215 vagina Anatomy 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 102000004266 Collagen Type IV Human genes 0.000 description 1
- 108010042086 Collagen Type IV Proteins 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 208000002197 Ehlers-Danlos syndrome Diseases 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 229920002079 Ellagic acid Polymers 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- QFJUYMMIBFBOJY-UXZRXANASA-N Panaxatriol Chemical compound C[C@]1([C@H]2CC[C@@]3([C@@H]2[C@H](O)C[C@H]2[C@]3(C[C@@H](O)[C@H]3C(C)(C)[C@@H](O)CC[C@@]32C)C)C)CCCC(C)(C)O1 QFJUYMMIBFBOJY-UXZRXANASA-N 0.000 description 1
- VIXIMKLMEZTTTC-UHFFFAOYSA-N Panaxatriol Natural products CC1(C)CCCC(O1)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5C(O)CC34C VIXIMKLMEZTTTC-UHFFFAOYSA-N 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 1
- 235000008758 anthocyanidins Nutrition 0.000 description 1
- 230000002605 anti-dotal effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000037365 barrier function of the epidermis Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 235000004132 ellagic acid Nutrition 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229940089161 ginsenoside Drugs 0.000 description 1
- 229930182494 ginsenoside Natural products 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 230000037373 wrinkle formation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of cosmetics, and in particular relates to an anti-wrinkle face cream and a preparation method thereof. The anti-wrinkle face cream comprises butanediol, ethylhexyl palmitate, caprylic/capric triglyceride, glycerol, polyglycerol-10, ethylhexyl isononanoate, polymethyl methacrylate, polydimethylsiloxane, ceteareth-21, cetostearyl alcohol, ceteareth-2, acrylic acid (ester) type/acrylamide copolymer, betaine, avocado fruit butter, a lactic acid bacillus/balausta fermentation product extract, an arctic rock chlamydomonas essence, a starfish essence, a ginseng extract, a lucid ganoderma extract, an apple extract, tocopheryl acetate and the like. The anti-wrinkle face cream provided by the invention is good in penetrability and easy to absorb, can effectively replenish water and preserve moisture, and can repair skin wrinkles and inhibit generation of the winkles, thereby delaying skin aging.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of crease-resistant facial cream and preparation method thereof.
Background technology
Wrinkle refers to that skin is subject to external environment impact, and form free free radical, free radical destroys the in-house collagen protein of human cell membrane, active substance, oxidative cell and the little microgroove, the wrinkle that are formed.Wrinkle occurs gradually.The order occurred is generally forehead, upper palpebra inferior, paropia, ear proparea, cheek, cervical region, lower chin, mouth week.Facial wrinkles is divided into atrophy wrinkle and loose wrinkle two type.Atrophy wrinkle refers to the wrinkle appeared on thin, easy jackknifing and dry skin, as those countless tiny wrinkles of circumference of eyes; Loose wrinkle refers to the wrinkle appeared in oily skin, and quantity is few, and texture is close and dark, as around forehead, lip, the wrinkle at lower jaw place, be the latest find of wrinkle formation.
Although skin aging is irreversible physiological phenomenon, its process can delay or slow down.For face wrinkles, common wrinkle removal method is operation reduce wrinkle, injection wrinkle removal and anti-wrinkle cosmetic.The treatment cost of operation reduce wrinkle and injection wrinkle removal is high, have a big risk, and is not that each consumer can bear, and anti-wrinkle cosmetic is one and well selects.Anti-wrinkle cosmetic is divided into again anti-wrinkle face mask, facial milk cleanser, and crease-resistant cosmetic water, facial cream, essence etc. are multiple, and anti-wrinkle face mask, facial milk cleanser are short in the time of staying of face, DeGrain, need life-time service, and use procedure is inconvenient; Anti-wrinkle essence successful, but cost is higher; And crease-resistant facial cream cost performance is high, and anti-wrinkle effect, but the problems such as crease-resistant facial cream ubiquity poor permeability, not easily absorption in the market, and anti-wrinkle effect need to improve.Along with growth in the living standard, people are more and more higher for the diversified requirement of cosmetics, also more and more higher to the quality requirements of cosmetics, need the new product providing more high-quality.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of crease-resistant facial cream, its good penetrability, easily absorbs, and crease-resistant composition is effectively sent to skin deep layer, repairs wrinkle of skin, suppresses wrinkle regeneration, delay skin aging.
To achieve these goals, technical scheme of the present invention is as follows:
A kind of crease-resistant facial cream, comprise the component of following weight percent meter: butanediol 5 ~ 10%, ethylhexyl palmitate 1 ~ 5%, caprylic/capric triglyceride 2 ~ 5%, glycerol 2 ~ 4%, Natrulon H-10 1 ~ 5%, different n-nonanoic acid Octyl Nitrite 1 ~ 5%, polymethyl methacrylate 1 ~ 3%, polydimethylsiloxane 1 ~ 2%, stereth-211 ~ 2%, cetearyl alcohol 0.5 ~ 2%, stereth-20.5 ~ 2%, acrylic acid (ester) class/acrylamide copolymer 0.1 ~ 0.8%, betanin 0.2 ~ 1%, Butyrospermum parkii fruit fat 0.1 ~ 1%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, Asterias amurensis Lutken elite 0.3 ~ 1%, Radix Ginseng extract 0.3 ~ 1%, Ganoderma extract 0.3 ~ 1%, Apples extract 0.3 ~ 1%, tocopherol acetas 0.1 ~ 0.5%, carbomer 0.1 ~ 0.5%, xanthan gum 0.01 ~ 0.05%, EDETATE SODIUM 0.01 ~ 0.03%, triethanolamine 0.05 ~ 0.3%, antiseptic 0.1 ~ 0.4%, essence 0.01 ~ 0.2% and water 60 ~ 70%.
As the preferred embodiment of the present invention, described crease-resistant facial cream is made up of the component of following weight percent meter: butanediol 8%, ethylhexyl palmitate 3%, caprylic/capric triglyceride 3%, glycerol 3%, Natrulon H-10 3%, different n-nonanoic acid Octyl Nitrite 2%, polymethyl methacrylate 1.5%, polydimethylsiloxane 1.7%, stereth-211.2%, cetearyl alcohol 0.8%, stereth-20.8%, acrylic acid (ester) class/acrylamide copolymer 0.45%, betanin 0.5%, Butyrospermum parkii fruit fat 0.2%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.4%, Asterias amurensis Lutken elite 0.6%, Radix Ginseng extract 0.5%, Ganoderma extract 0.5%, Apples extract 0.5%, tocopherol acetas 0.3%, carbomer 0.2%, xanthan gum 0.03%, EDETATE SODIUM 0.02%, triethanolamine 0.15%, antiseptic 0.3%, essence 0.12%, surplus is water.
Further, described antiseptic is the compositions of methyl hydroxybenzoate and propyl hydroxybenzoate, and the weight ratio of described methyl hydroxybenzoate and propyl hydroxybenzoate is 2:1.
In technical solution of the present invention, the humectant properties of the unsaturated fatty acid that described Butyrospermum parkii fruit fat contains is very similar to the sebaceous gland of human body skin, it is natural emollient, it has extraordinary penetration, skin bottom can be penetrated into fast after contact skin, and the generation of the collagen protein of deep skin can be excited, the supporting construction of regeneration and reparation skin.
Described lactobacillus/Punica granatum L. tunning extract contains a large amount of ellagic acids, polyphenol and anthocyanidin, and its non-oxidizability is strong, can effectively in and free radical, enhance metabolism, reduce visible microgroove.
Described arctic Ascophyllum nodosum elite is rich in algin body, brown algae polyphenols, sodium alginate, algae carotene and ocean trace element, skin thickness can be increased, improve the mechanical performance of skin, improve barrier function, promote collagen protein and elastin laminin with become, suppress digestive enzyme, thus improve the texture of skin, color and luster and brightness.
Described Asterias amurensis Lutken elite can promote the metabolism of skin, increase epidermal barrier regeneration, more increase the synthesis of glycosaminoglycan (GAGS) and III, type Ⅳ collagen albumen simultaneously, help skin effectively to anti-wrinkle, make skin water tender flexible, and without any side effect and zest.
Described Radix Ginseng extract contains ginsenoside, panaxatriol, several mineral materials and vitamin, there is the blood circulation promoting subcutaneous capillary, increase the effects such as the nutrition supply of skin, can also the balance of regulation of skin moisture, prevent xerosis cutis from dewatering, increase the elasticity of skin, play and keep bright and clean tender, the effect that prevents or reduce wrinkle of skin of skin.
Described Ganoderma extract contains the composition of check melanin and the multiple trace element etc. to skin beneficiating, these compositions can by reducing human free radical, accelerate the regeneration of cell, increase the thickness of skin and increase collagen, reach plump skin, eliminate the effect of microgroove and wrinkle; Polysaccharide component wherein by keeping and regulation of skin aqueous, can recover skin elasticity, making skin wet, exquisiteness.
Described Apples extract can activate the stem cell of skin base layer, allows Skin Cell regenerate, and postpones the appearance of wrinkle, it also has oxidation resistance, the ripe aging process of the skin that effectively slows down, also can improve the dim heavy and wrinkle of skin, gives skin lock outlet capacity.
The crease-resistant facial cream of the present invention contains lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, Radix Ginseng extract, Ganoderma extract, the multiple natural plant compositions such as Apples extract, again in conjunction with butanediol of the present invention, ethylhexyl palmitate, caprylic/capric triglyceride, glycerol, Natrulon H-10, different n-nonanoic acid Octyl Nitrite, polymethyl methacrylate, polydimethylsiloxane, stereth-21, cetearyl alcohol, stereth-2, the basic materials such as acrylic acid (ester) class/acrylamide copolymer, each component is worked in coordination with, make the crease-resistant facial cream good penetrability of the present invention, easy absorption, deep water supplement moisturizing, nourish maintenance skin, strengthen skin elastic and improve drying, relaxation, repair impaired or innutritive cell, crease-resistant composition is effectively sent to skin deep layer simultaneously, repair wrinkle of skin, suppress wrinkle regeneration, delay skin aging.
Present invention also offers the preparation method of above-mentioned crease-resistant facial cream, specifically comprise the following steps:
S1, by ethylhexyl palmitate, caprylic/capric triglyceride, different n-nonanoic acid Octyl Nitrite, polydimethylsiloxane, cetearyl alcohol, Butyrospermum parkii fruit fat, tocopherol acetas, antiseptic, polymethyl methacrylate, stereth-21, stereth-2, be placed in oil phase pot, be heated to 80 ~ 85 DEG C, obtain material A after stirring and dissolving is complete, be incubated for subsequent use;
S2, Jiang Shui, butanediol, glycerol, Natrulon H-10, EDETATE SODIUM, carbomer, xanthan gum, betanin add in aqueous phase pot, being heated to 85 ~ 90 DEG C dissolves completely, in the emulsifying pot of then suction preheating, open and stir, again by slow for material A suction emulsifying pot, lower the temperature after homogenizing 5 ~ 10min;
S3, be down to 60 DEG C, add acrylic acid (ester) class/acrylamide copolymer and triethanolamine, homogenizing 3 ~ 5min;
S4, continue to be cooled to 45 DEG C, adding lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, Radix Ginseng extract, Ganoderma extract, Apples extract and essence is stirred to evenly, sampling Detection, namely qualified rear discharging obtains crease-resistant facial cream.
Further, the rotating speed of described homogenizing is 2000 ~ 3000rpm.
Further, the mixing speed of described stirring is 40 ~ 50r/min.
Therefore, compared with prior art, advantage of the present invention is:
(1) the crease-resistant facial cream of the present invention contains lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, Radix Ginseng extract, Ganoderma extract, Apples extract, the multiple natural plant active components such as Butyrospermum parkii fruit fat, deep water supplement moisturizing, nourish maintenance skin, improve xerosis cutis, relaxation, crease-resistant composition is effectively sent to skin deep layer simultaneously, repair impaired or innutritive cell, effectively calm down microgroove, the dry stricture of vagina of obvious minimizing and wrinkle, and prevent wrinkle from regenerating, slowing down skin aging, skin beauty water is moistened smooth, high resilience, promote skin year slight.
(2) the crease-resistant facial cream safety and stability of the present invention, good penetrability, easily absorbs, and uses rear skin salubrious not sticky; And the preparation method of the crease-resistant facial cream of the present invention is simple, condition is controlled, process stabilizing, can be applicable.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, crease-resistant facial cream of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
In crease-resistant facial cream described in the embodiment of the present invention, the information such as producer and article No. of part material is as follows:
Raw material and the proportioning (by weight percentage) of the embodiment of the present invention 1 ~ 3 and comparative example one, two facial cream are as follows:
The preparation method of the crease-resistant facial cream of the embodiment of the present invention 1 ~ 3 is as follows:
S1, by ethylhexyl palmitate, caprylic/capric triglyceride, different n-nonanoic acid Octyl Nitrite, polydimethylsiloxane, cetearyl alcohol, Butyrospermum parkii fruit fat, tocopherol acetas, antiseptic, polymethyl methacrylate, stereth-21, stereth-2, be placed in oil phase pot, be heated to 80 ~ 85 DEG C, obtain material A after stirring and dissolving is complete, be incubated for subsequent use;
S2, Jiang Shui, butanediol, glycerol, Natrulon H-10, EDETATE SODIUM, carbomer, xanthan gum, betanin add in aqueous phase pot, being heated to 85 ~ 90 DEG C dissolves completely, in the emulsifying pot of then suction preheating, open and stir, again by slow for material A suction emulsifying pot, lower the temperature after homogenizing 5 ~ 10min;
S3, be down to 60 DEG C, add acrylic acid (ester) class/acrylamide copolymer and triethanolamine, homogenizing 3 ~ 5min;
S4, continue to be cooled to 45 DEG C, adding lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, Radix Ginseng extract, Ganoderma extract, Apples extract and essence is stirred to evenly, sampling Detection, namely qualified rear discharging obtains crease-resistant facial cream.
Wherein, the rotating speed of described homogenizing is 2000rpm; The mixing speed of described stirring is 45r/min.
The preparation method of the preparation method reference embodiment of the present invention of comparative example one, two.
Meet the pertinent regulations requirement of QB/T1857-2013 through inspection embodiment 1 ~ 3 product, sense index (color and luster, fragrance, structure) meets industry regulation, and physical and chemical index (PH, heat-resisting, cold-resistant, active matter) meets industry regulation.
test example one, Product Safety evaluation (experiment of human body skin patch)
One, trial target: the crease-resistant facial cream that embodiment 1 ~ 3, comparative example one, two prepare
Tested crowd's number: 50 people, women
Age: between 30 ~ 60 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: 5 groups, often organize 10 people, 38 ± 2 years old mean age.
Two, patch method: select qualified speckle examination device, with closed patch experiment method, tested material being about 0.020g ~ 0.025g drips in speckle examination device, external special adhesive tape is covered on experimenter back, tested material is removed after 24 hours, within after removing respectively 0.5,6,12,24,48 hour, observe dermoreaction, according to its result of dermoreaction grade scale record in " cosmetics health specification ".
Three, experimental result: human skin patch result shows: each group experimenter is by the patch test of the crease-resistant facial cream of embodiment 1 ~ 3, comparative example one, two, dermoreaction is observed at 0.5,6,12,24,48 hour, wherein there is skin adverse reaction in 0 example, the crease-resistant facial cream use safety described in explanation.
test example two, product effect assessment
part I:
One, trial target: the crease-resistant facial cream that embodiment 1 prepares
Two, tested crowd
Sex number: female, 30 people
Age: between 35 ~ 55 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Three, method of testing: adopt the skin elasticity CotometerMPA580 main frame that German Courage+Khazaka company (German CK company) manufactures, the probe used is ReviscometerRV600 elastic fibrous tissue test probe, surveys and averages for five times.Test zone: place between the eyebrows middle is 2cm forehead region, lower lip middle down 2cm chin area, the left and right cheek region of nose and pupil intersection place up.First measure the blank value (R2, R5, R7) of 30min after tested region clean, then specify that experimenter adheres to using above-mentioned trial target every day sooner or later, test test zone skin elasticity index R2, R5, R7 value (in test process, negative pressure is constant is 450mbar) after 1 week, 2 weeks, 3 weeks, 4 weeks respectively.
Index illustrates: skin elasticity index R2, R5, R7 are more close to 1, and the elasticity of skin is better.
R2=Ua/Uf；R5=Ur/Ue；R7=Ur/Uf
Uf---skin maximum tension amount
Ue---constant negative pressure is added to after on skin, the amount of tension of skin during 0.1 second, positioning elastic part amount of tension.
Ur---cancel after negative pressure, skin will restore to the original state rapidly state, is divided into elastic score value Ur equally, namely cancels negative pressure after 0.1 second, the recovery value of skin and visco-elastic portions value, or claim plastic value.
Ua---from cancelling the recovery value of negative pressure to skin when follow-on test skin surface adds negative pressure more next time.
Four, test result is as following table 1.
The crease-resistant facial cream table with test results of table 1 embodiment 1
From upper table 1: use crease-resistant facial cream first week rear R2, R5, R7 of embodiment 1 to increase to some extent, within 4th week, R2, R5, R7 all rise obviously, and R2, R5, R7 value levels off to 1, the skin elasticity index of experimenter has very large lifting, as can be seen here, this crease-resistant facial cream has increases skin elasticity, antidotal effect.
part II:
One, trial target: embodiment 1 ~ 3, crease-resistant facial cream prepared by comparative example one, two
Two, tested crowd
Sex number: female, 150 people
Age: between 35 ~ 55 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 5 groups, often organize 30 people, 43 ± 2 years old mean age.
Three, method of testing: respectively use-case 1 ~ 3, crease-resistant facial cream prepared by comparative example one, two, observes and experiences result of use.Using method: after experimenter cleans face, appropriate facial cream is in the palm of the hand, even point is applied to face skin, massage is until absorb completely gently, the every day of each use sooner or later once, adhere to use one month, at least check weekly once to understand with or without whole body and local untoward reaction, and itemized record result.
Four, testing evaluation result is as follows:
(one month) on probation feedback conclusive table of the crease-resistant facial cream of table 2 embodiment 1
(one month) on probation feedback conclusive table of the crease-resistant facial cream of table 3 embodiment 2
(one month) on probation feedback conclusive table of the crease-resistant facial cream of table 4 embodiment 3
(one month) on probation feedback conclusive table of table 5 comparative example primary antibodie drawn grain frost
(one month) on probation feedback conclusive table of the crease-resistant facial cream of table 6 comparative example two
(1) from upper table 2 ~ 4, crease-resistant facial cream the liking and approving extensively by experimenter of the embodiment of the present invention 1 ~ 3, experimenter all represents the crease-resistant facial cream good penetrability of the present invention, easy absorption, uses rear skin around the eyes salubrious not sticky, to skin supply nutrition, promote skin metabolism, crease-resistant composition is effectively sent to skin deep layer, effectively calms down microgroove, reduce dry stricture of vagina and wrinkle, slowing down skin aging, and effectively improve drying, relaxation, skin beauty water is moistened smooth, high resilience.The highest with the degree of recognition of the crease-resistant facial cream of embodiment 1 in embodiment 1 ~ 3, therefore embodiment 1 is preferred embodiment.
(2) from upper table 5 ~ 6, comparative example one and the crease-resistant facial cream of comparative example two all lack some component in the crease-resistant facial cream formula of the present invention, its result of use is all not as embodiment 1 ~ 3, illustrate that the present invention's crease-resistant facial cream formula is not obtained by the simple combination of each component, then further illustrate between each component of formula of the present invention and there is synergism.
There is not people to occur allergic phenomena in whole experimenter simultaneously, all do not occur the situations such as skin pruritus, twinge, redness yet.Therefore, the gentle safety of the crease-resistant facial cream of the present invention, can life-time service.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.
Claims (6)
1. a crease-resistant facial cream, it is characterized in that, comprise the component of following weight percent meter: butanediol 5 ~ 10%, ethylhexyl palmitate 1 ~ 5%, caprylic/capric triglyceride 2 ~ 5%, glycerol 2 ~ 4%, Natrulon H-10 1 ~ 5%, different n-nonanoic acid Octyl Nitrite 1 ~ 5%, polymethyl methacrylate 1 ~ 3%, polydimethylsiloxane 1 ~ 2%, stereth-211 ~ 2%, cetearyl alcohol 0.5 ~ 2%, stereth-20.5 ~ 2%, acrylic acid (ester) class/acrylamide copolymer 0.1 ~ 0.8%, betanin 0.2 ~ 1%, Butyrospermum parkii fruit fat 0.1 ~ 1%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, Asterias amurensis Lutken elite 0.3 ~ 1%, Radix Ginseng extract 0.3 ~ 1%, Ganoderma extract 0.3 ~ 1%, Apples extract 0.3 ~ 1%, tocopherol acetas 0.1 ~ 0.5%, carbomer 0.1 ~ 0.5%, xanthan gum 0.01 ~ 0.05%, EDETATE SODIUM 0.01 ~ 0.03%, triethanolamine 0.05 ~ 0.3%, antiseptic 0.1 ~ 0.4%, essence 0.01 ~ 0.2% and water 60 ~ 70%.
2. crease-resistant facial cream as claimed in claim 1, it is characterized in that, be made up of the component of following weight percent meter: butanediol 8%, ethylhexyl palmitate 3%, caprylic/capric triglyceride 3%, glycerol 3%, Natrulon H-10 3%, different n-nonanoic acid Octyl Nitrite 2%, polymethyl methacrylate 1.5%, polydimethylsiloxane 1.7%, stereth-211.2%, cetearyl alcohol 0.8%, stereth-20.8%, acrylic acid (ester) class/acrylamide copolymer 0.45%, betanin 0.5%, Butyrospermum parkii fruit fat 0.2%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.4%, Asterias amurensis Lutken elite 0.6%, Radix Ginseng extract 0.5%, Ganoderma extract 0.5%, Apples extract 0.5%, tocopherol acetas 0.3%, carbomer 0.2%, xanthan gum 0.03%, EDETATE SODIUM 0.02%, triethanolamine 0.15%, antiseptic 0.3%, essence 0.12%, surplus is water.
3. crease-resistant facial cream as claimed in claim 1 or 2, is characterized in that, described antiseptic is the compositions of methyl hydroxybenzoate and propyl hydroxybenzoate, and the weight ratio of described methyl hydroxybenzoate and propyl hydroxybenzoate is 2:1.
4. prepare a method for crease-resistant facial cream as claimed in claim 1 or 2, it is characterized in that, comprise the following steps:
S1, by ethylhexyl palmitate, caprylic/capric triglyceride, different n-nonanoic acid Octyl Nitrite, polydimethylsiloxane, cetearyl alcohol, Butyrospermum parkii fruit fat, tocopherol acetas, antiseptic, polymethyl methacrylate, stereth-21, stereth-2, be placed in oil phase pot, be heated to 80 ~ 85 DEG C, obtain material A after stirring and dissolving is complete, be incubated for subsequent use;
S2, Jiang Shui, butanediol, glycerol, Natrulon H-10, EDETATE SODIUM, carbomer, xanthan gum, betanin add in aqueous phase pot, being heated to 85 ~ 90 DEG C dissolves completely, in the emulsifying pot of then suction preheating, open and stir, again by slow for material A suction emulsifying pot, lower the temperature after homogenizing 5 ~ 10min;
S3, be down to 60 DEG C, add acrylic acid (ester) class/acrylamide copolymer and triethanolamine, homogenizing 3 ~ 5min;
S4, continue to be cooled to 45 DEG C, adding lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, Radix Ginseng extract, Ganoderma extract, Apples extract and essence is stirred to evenly, sampling Detection, namely qualified rear discharging obtains crease-resistant facial cream.
5. the preparation method of crease-resistant facial cream as claimed in claim 4, is characterized in that, the rotating speed of described homogenizing is 2000 ~ 3000rpm.
6. the preparation method of crease-resistant facial cream as claimed in claim 4, is characterized in that, the mixing speed of described stirring is 40 ~ 50r/min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510675219.6A CN105147591B (en) | 2015-10-19 | 2015-10-19 | A kind of crease-resistant face cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510675219.6A CN105147591B (en) | 2015-10-19 | 2015-10-19 | A kind of crease-resistant face cream and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105147591A true CN105147591A (en) | 2015-12-16 |
| CN105147591B CN105147591B (en) | 2018-06-05 |
Family
ID=54788888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510675219.6A Active CN105147591B (en) | 2015-10-19 | 2015-10-19 | A kind of crease-resistant face cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105147591B (en) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902468A (en) * | 2016-05-20 | 2016-08-31 | 秦瑜 | Whitening anti-aging facial cream |
| CN106074279A (en) * | 2016-07-11 | 2016-11-09 | 广州丹奇日用化工厂有限公司 | A kind of anti-ageing facial cream containing Herba Artemisiae montanae Artemisia extract and preparation method thereof |
| CN106176466A (en) * | 2016-08-30 | 2016-12-07 | 思拓科（上海）生物科技股份有限公司 | Child's facial cream and preparation method thereof |
| CN106420445A (en) * | 2016-09-19 | 2017-02-22 | 广东丸美生物技术股份有限公司 | Skin care matrix with moisture preserving and oxidation resisting effects as well as preparation method and application of skin care matrix |
| CN106727037A (en) * | 2017-01-24 | 2017-05-31 | 王前行 | The gentle nutrition face cream of plant |
| CN106924078A (en) * | 2017-02-17 | 2017-07-07 | 德宏州春雪化妆品销售有限公司 | A kind of Moringa frost, Moringa breast and preparation method thereof |
| CN107184455A (en) * | 2017-05-18 | 2017-09-22 | 上海伊匠生物科技有限公司 | A kind of natural organic face cream |
| CN107233218A (en) * | 2017-06-20 | 2017-10-10 | 广东盛美化妆品有限公司 | A kind of layered liquid crystal emollient cream and preparation method thereof |
| CN107519121A (en) * | 2017-09-12 | 2017-12-29 | 陈德兴 | De-etiolation anti-aging face cream and preparation method thereof |
| CN107582499A (en) * | 2017-09-12 | 2018-01-16 | 陈德兴 | Whitening is compacted restructuring compound for the neck and preparation method thereof |
| CN108158968A (en) * | 2018-01-17 | 2018-06-15 | 浙江理工大学 | A kind of tender skin shines face multiple-effect washing cream and preparation method thereof |
| CN108272727A (en) * | 2018-04-08 | 2018-07-13 | 上海粉蝶化妆品有限公司 | A kind of rain lily meat lip orchid face cream |
| CN108578329A (en) * | 2018-07-19 | 2018-09-28 | 广州市瓷颜化妆品有限公司 | Seven white plant whitening of one kind repairing face cream and preparation method thereof |
| CN108721162A (en) * | 2018-06-01 | 2018-11-02 | 广州锦同生物科技有限公司 | A kind of smooth essence breast of agalloch eaglewood and preparation method thereof |
| CN109453062A (en) * | 2018-12-07 | 2019-03-12 | 广州天玺生物科技有限公司 | A kind of preparation method of polypeptide anti-wrinkle maintenance essence |
| CN110025555A (en) * | 2019-03-28 | 2019-07-19 | 广州市茗妍化妆品有限公司 | A kind of repair cream and preparation method thereof |
| CN110934793A (en) * | 2019-12-18 | 2020-03-31 | 佛山科学技术学院 | A kind of cream and preparation method thereof |
| CN111888309A (en) * | 2020-08-14 | 2020-11-06 | 广州致美日化科技有限公司 | Water acupuncture cream composition |
| CN112402309A (en) * | 2020-10-30 | 2021-02-26 | 广州市妆妍生物技术有限公司 | Multi-vitamin mineral essence cream and preparation method thereof |
| CN115778835A (en) * | 2022-12-29 | 2023-03-14 | 羽楠(广州)化妆品有限公司 | Polyglycerol ester moisturizer and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417466A (en) * | 2013-08-15 | 2013-12-04 | 江南大学 | Natural moisture-preserving and skin-protecting composition and application thereof in cosmetics |
| CN104434747A (en) * | 2014-10-13 | 2015-03-25 | 金日制药（中国）有限公司 | Face cream with anti-aging function and preparation method of face cream |
| CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技（上海）有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
| CN104825382A (en) * | 2015-05-26 | 2015-08-12 | 成都肤格特商贸有限公司 | Biotechnology skin-whitening cosmetics |
-
2015
- 2015-10-19 CN CN201510675219.6A patent/CN105147591B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417466A (en) * | 2013-08-15 | 2013-12-04 | 江南大学 | Natural moisture-preserving and skin-protecting composition and application thereof in cosmetics |
| CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技（上海）有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
| CN104434747A (en) * | 2014-10-13 | 2015-03-25 | 金日制药（中国）有限公司 | Face cream with anti-aging function and preparation method of face cream |
| CN104825382A (en) * | 2015-05-26 | 2015-08-12 | 成都肤格特商贸有限公司 | Biotechnology skin-whitening cosmetics |
Non-Patent Citations (1)
| Title |
|---|
| 新浪湖北时尚: "WATER360矿泉水透保湿乳", 《新浪湖北》 * |
Cited By (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902468A (en) * | 2016-05-20 | 2016-08-31 | 秦瑜 | Whitening anti-aging facial cream |
| CN106074279A (en) * | 2016-07-11 | 2016-11-09 | 广州丹奇日用化工厂有限公司 | A kind of anti-ageing facial cream containing Herba Artemisiae montanae Artemisia extract and preparation method thereof |
| CN106176466B (en) * | 2016-08-30 | 2019-02-22 | 思拓科（上海）生物科技股份有限公司 | Children's face cream and preparation method thereof |
| CN106176466A (en) * | 2016-08-30 | 2016-12-07 | 思拓科（上海）生物科技股份有限公司 | Child's facial cream and preparation method thereof |
| CN106420445A (en) * | 2016-09-19 | 2017-02-22 | 广东丸美生物技术股份有限公司 | Skin care matrix with moisture preserving and oxidation resisting effects as well as preparation method and application of skin care matrix |
| CN106420445B (en) * | 2016-09-19 | 2019-06-11 | 广东丸美生物技术股份有限公司 | A kind of skin matrix and the preparation method and application thereof with moisturizing and anti-oxidation efficacy |
| CN106727037A (en) * | 2017-01-24 | 2017-05-31 | 王前行 | The gentle nutrition face cream of plant |
| CN106924078A (en) * | 2017-02-17 | 2017-07-07 | 德宏州春雪化妆品销售有限公司 | A kind of Moringa frost, Moringa breast and preparation method thereof |
| CN107184455A (en) * | 2017-05-18 | 2017-09-22 | 上海伊匠生物科技有限公司 | A kind of natural organic face cream |
| CN107233218A (en) * | 2017-06-20 | 2017-10-10 | 广东盛美化妆品有限公司 | A kind of layered liquid crystal emollient cream and preparation method thereof |
| CN107519121A (en) * | 2017-09-12 | 2017-12-29 | 陈德兴 | De-etiolation anti-aging face cream and preparation method thereof |
| CN107582499A (en) * | 2017-09-12 | 2018-01-16 | 陈德兴 | Whitening is compacted restructuring compound for the neck and preparation method thereof |
| CN108158968A (en) * | 2018-01-17 | 2018-06-15 | 浙江理工大学 | A kind of tender skin shines face multiple-effect washing cream and preparation method thereof |
| CN108272727A (en) * | 2018-04-08 | 2018-07-13 | 上海粉蝶化妆品有限公司 | A kind of rain lily meat lip orchid face cream |
| CN108721162A (en) * | 2018-06-01 | 2018-11-02 | 广州锦同生物科技有限公司 | A kind of smooth essence breast of agalloch eaglewood and preparation method thereof |
| CN108578329A (en) * | 2018-07-19 | 2018-09-28 | 广州市瓷颜化妆品有限公司 | Seven white plant whitening of one kind repairing face cream and preparation method thereof |
| CN109453062A (en) * | 2018-12-07 | 2019-03-12 | 广州天玺生物科技有限公司 | A kind of preparation method of polypeptide anti-wrinkle maintenance essence |
| CN110025555A (en) * | 2019-03-28 | 2019-07-19 | 广州市茗妍化妆品有限公司 | A kind of repair cream and preparation method thereof |
| CN110934793A (en) * | 2019-12-18 | 2020-03-31 | 佛山科学技术学院 | A kind of cream and preparation method thereof |
| CN111888309A (en) * | 2020-08-14 | 2020-11-06 | 广州致美日化科技有限公司 | Water acupuncture cream composition |
| CN112402309A (en) * | 2020-10-30 | 2021-02-26 | 广州市妆妍生物技术有限公司 | Multi-vitamin mineral essence cream and preparation method thereof |
| CN115778835A (en) * | 2022-12-29 | 2023-03-14 | 羽楠(广州)化妆品有限公司 | Polyglycerol ester moisturizer and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105147591B (en) | 2018-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105147591A (en) | Anti-wrinkle face cream and preparation method thereof | |
| CN105125476B (en) | A kind of anti-wrinkle essence and preparation method thereof | |
| CN105147590B (en) | A kind of anti-wrinkle eye cream and preparation method thereof | |
| CN104666236B (en) | A kind of preserving moisture and protecting skin facial film | |
| CN106580762B (en) | Have effects that comfort the crease-resistant composite skin care product of line, eye cream and preparation method thereof | |
| CN103340813B (en) | Collagenic skin care emulsion, and preparation method and application thereof | |
| CN105168112A (en) | Anti-wrinkle toner and preparation method thereof | |
| CN104546650B (en) | A kind of facial mask for the skin that compacts and preparation method thereof | |
| CN104644507B (en) | A kind of nursing class cream cream composition | |
| CN105250184A (en) | Whitening anti-aging essence liquid and preparation method thereof | |
| CN104887609A (en) | Moisturizing mask liquid and preparation method thereof | |
| CN110115704B (en) | Enzyme composition and application thereof in cosmetics with whitening function | |
| CN112641657B (en) | Moisturizing and repairing face cream and preparation method thereof | |
| CN105395443A (en) | Anti-aging eye cream and preparation method thereof | |
| WO2018036356A1 (en) | Peach gum mask | |
| CN104352418A (en) | An Anti-Aging Serum | |
| CN105287331A (en) | Anti-wrinkle cleansing lotion and preparation method thereof | |
| CN109381356A (en) | A kind of sleep late frost and preparation method thereof | |
| JP6007188B2 (en) | Cosmetic composition comprising Honda walla extract, mill extract and wakame extract | |
| CN111407685A (en) | Anti-aging composition of recombinant fibronectin-human-like collagen and preparation method thereof | |
| CN106377488A (en) | Skin care substrate with moisture retaining and oil controlling effects and preparation method and application thereof | |
| CN104352385A (en) | anti aging serum | |
| CN105287292A (en) | Whitening moisture-retention face cream and preparation method thereof | |
| CN109350591A (en) | A kind of U.S. face dried noodle film and preparation method thereof | |
| CN105287340A (en) | Whitening moisture-retention eye cream and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: Huadu District, Guangdong city of Guangzhou province 510880 Flower Town Qiyuan Road No. 28 Applicant after: Guangzhou Kema biotechnology Polytron Technologies Inc Address before: Hua Town, Huadu District, Guangdong Province, 510880 Avenue, Guangzhou City Applicant before: Kerma (unit of kinetic energy) bio tech ltd, Guangzhou |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |