CN105147555B - A kind of Islamic plant composition for skin care, Islamic plant cream and its preparation method and application - Google Patents
A kind of Islamic plant composition for skin care, Islamic plant cream and its preparation method and application Download PDFInfo
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- CN105147555B CN105147555B CN201510587653.9A CN201510587653A CN105147555B CN 105147555 B CN105147555 B CN 105147555B CN 201510587653 A CN201510587653 A CN 201510587653A CN 105147555 B CN105147555 B CN 105147555B
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- 238000002156 mixing Methods 0.000 claims abstract description 28
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Abstract
The invention discloses a kind of Islamic plant composition for skin care, Islamic plant cream and its preparation method and application, belong to cosmetic field.The Islamic skin care compositions of the present invention is made of the raw material of following parts by weight：Print plus 30~60 parts of fruit, 20~60 parts of balsamine, 10~30 10~30 parts of part, bar denier wood of olea europaea fruit.It is prepared by mixing into the Islamic plant cream of the present invention after above-mentioned each bulk pharmaceutical chemicals compounding in proportion through extracting obtained plant extracts and skin care field customary adjuvant.The Islamic plant composition for skin care and Islamic plant cream of the present invention has effects that oil-control, removes free radical and Red blood streak dispelling, and non-stimulated to skin safe through the confirmation of human body patch test.The present invention is directed to " Moslem " people, discloses a kind of Islamic plant composition for skin care, Islamic plant cream, and raw material sources are obtained and are easy, preparation method is easy, green safe, has good application prospect and market prospects in natural.
Description
Technical field
The present invention relates to a kind of skin care compositions, and in particular to one kind having oil-control, removes free radical and Red blood streak dispelling work(
The Islamic plant composition for skin care of effect, Islamic plant cream and its preparation method and application, belong to cosmetic field.
Background technology
Latest data shows that for world population to break through 7,000,000,000 high pointes, wherein China is the populous nation that beats the world,
Secondary is India；Entire Asia population is to reach 4,200,000,000.According to statistics, current Moslem's population alreadys exceed 1,600,000,000, and pre-
Counting will be close to 2,000,000,000 to the year two thousand thirty Moslem's population.Up to the present, Asia Moslem population has reached 700,000,000 people or more,
Account for about the 62% of global Moslem's population.In the world, in the country that Moslem's population ranks forefront ten, the first four place country
All it is Asian countries, is Indonesia (200,000,000), Pakistani (1.8 hundred million), India (1.8 hundred million), Bangladesh (1.5 respectively
Hundred million).
Moslem's cosmetics must could be received through Halal certifications by vast " Moslem " people, and the guidance of product design is thought
Think to be natural, environmentally friendly, healthy；Animal fat is not added, using extracts such as natural plants fruit, rhizomes as main active substances,
It is equipped with advanced production technology and production procedure is made.Currently, the superfine cosmetics sales shop of state's inside trade, almost without complying fully with
In the cosmetics of " Moslem " crowd demand.Due to particularity such as Moslem's cosmetic material source, certifications, so that Moslem
The available cosmetics of the people are fewer and fewer.
In face of the particularity of numerous Moslem crowds and the consumer group, targetedly develops Islamic cosmetics and provide
Corresponding cosmetics consumption concept, has a vast market foreground.
Invention content
First of the present invention is designed to provide a kind of Islamic plant composition for skin care, and the composition has oil-control, clear
The effect of except free radical and Red blood streak dispelling；
Second object of the present invention is to provide a kind of preparation method of the Islamic plant composition for skin care；
Third object of the present invention is to provide a kind of Islamic plant cream, which includes above-mentioned Islamic
The active constituent of plant composition for skin care；
Fourth object of the present invention is to provide a kind of method preparing the Islamic plant cream；
The 5th of the present invention is designed to provide the Islamic plant composition for skin care and is preparing with oil-control, removing certainly
By the application in base and the cosmetics of Red blood streak dispelling effect.
Above-mentioned purpose of the present invention is achieved by the following technical solution：
A kind of Islamic plant composition for skin care, which is characterized in that be made of the bulk pharmaceutical chemicals of following parts by weight：Print plus fruit 30~
60 parts, 20~60 parts of balsamine, 10~30 10~30 parts of part, bar denier wood of olea europaea fruit.
In the present invention, it is preferred to, the parts by weight of each bulk pharmaceutical chemicals are：The parts by weight of each bulk pharmaceutical chemicals are：Print plus fruit 40~60
Part, 40~60 parts of balsamine, 20~30 15~30 parts of part, bar denier wood of olea europaea fruit.
The present invention utilizes advanced biotechnology, in conjunction with the theory of traditional Chinese medical science of Chinese tradition, by print plus fruit, balsamine, oily olive
Olive fruit, Ba Danmu are effectively combined in together, form compound preparation, and as the active component of Islamic surfactant.This matches
Side is the optimum formula that inventor obtains through creative work, is formulated collaboration action between each component.
Wherein, print plus fruit：Also known as print plus peanut, plukenetia volubilis linneo are the perennial woody climber oilseed plant of Euphorbiaceae.It
Contain abundant oil in fruit, wherein 70% or more is unsaturated fatty acid, skin histology binding force can be enhanced, repair sebum
Film enhances the barrier function of epidermis.Transdermal dehydration is reduced, the moisturizing rate of skin is improved, soft skin increases elasticity, reduces skin
The generation of skin inflammation improves pachylosis, low and deep situation.Meanwhile the natural VE (tocopherol) of high-content and assigning it
Good scavenging activated oxygen, the function of anti-aging.
Balsamine：It is sweet in flavor, bitter, slightly warm in nature；There are dispelling wind and eliminating dampness, promoting blood circulation and stopping pain, removing toxic substances desinsection and other effects.Main rheumatism limbs impotence
Useless, waist coerces pain, and women closes abdominal pain, and postpartum blood stasis not to the greatest extent, fracture, skin sore, venomous snake bite, leukorrhea by traumatic injury, the goose palm
Wind, onychomycosis.
Olea europaea fruit：Olive tree fruit, meridian distribution of property and flavor：Hardship is trembled with fear.Enter liver, the heart two passes through；Effect：It is calming the liver, clear
Thermal detoxification.For syndrome of upper hyperactivity of liver yang, burn and scald；Have the function of anti-aging, radiation protection, promote digestive system etc..
Ba Danmu：Ba Danmu also known as almond are also commonly called as shell almond, and it is dry to be that the Xinjiang Uygur people most value
Fruit is rich in multiple nutritional components.Ba Danmu, which has, to calm the nerves, and has one's ideas straightened out, brain tonic, improving eyesight kidney-nourishing, moistening lung, ease constipation, production of sperm, and body-building is good for
The functions such as stomach.It cures mainly palpitaition to breath with cough, deficiency of kidney-QI, soreness and weakness of waist and knees, the illnesss such as impotence frequent micturition.
Further, the present invention provides a kind of method preparing the Islamic plant composition for skin care, feature exists
In including the following steps：
(1) each bulk pharmaceutical chemicals are weighed respectively according to the parts by weight, after bulk pharmaceutical chemicals are crushed, be uniformly mixed, obtain plant
Composition；
(2) it is that 60%~95% ethyl alcohol carries out ultrasonic extraction that concentration of volume percent is added into plant composition, is obtained
Ultrasonic extraction liquid；
(3) it is filtered after standing ultrasonic extraction liquid, obtains filtrate；
(4) after addition 1,3-BDO is miscible uniformly in filtrate, the ethyl alcohol in solution is rotated out, is filtered by vacuum, filter is collected
Liquid to get.
In the present invention, it is preferred to, the crushing described in step (1) is to be crushed to 80~120 mesh；Plant group in step (2)
The ratio for closing amount of substance and 60%~95% ethyl alcohol volume is 1:10~1:30, g/mL；The condition of the ultrasonic extraction is：It carries
It is 40 DEG C~70 DEG C to take temperature, and the time is 0.5~2h, and ultrasonic power is 300~500W；Step (3) the specific steps are：To super
Sound extracting solution stops heating, and ultrasonic extraction liquid is stood 2~4 hours, after the filtering of 100~200 mesh, obtains filtrate；The tool of step (4)
Body step is：In filtrate be added with the isometric 1,3-BDO of 60%~95% ethyl alcohol it is miscible uniformly after, rotate out in solution
Ethyl alcohol, vacuum filtration, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Further, the present invention provides a kind of Islamic plant creams, which is characterized in that the Islamic plant cream by
The raw material of following weight percent forms：
In the present invention, it is preferred to, the emulsifier is cetostearyl alcohol/cocoyl glucoside；The thickener
For xanthans；The skin conditioning agent is the HA solution (Sodium Hyaluronate) that mass fraction is 1%；The metal-chelator
For EDETATE SODIUM；The preservative is selected from methyl p-hydroxybenzoate, propylparaben, the different thiophene of propylene glycol/methyl
Oxazoline ketone/iodine propilolic alcohol butyl mephenesin Carbamate/sodium chloride, Phenoxyethanol/Sensiva SC50 and P-hydroxybenzoic acid isobutyl
At least one of ester.
In the present invention, it is preferred to, the plant extracts is prepared using following methods：
(1) each bulk pharmaceutical chemicals, print plus 30~60 parts of fruit, 20~60 parts of balsamine, olea europaea fruit are weighed according to following weight parts
10~30 10~30 parts of part, bar denier wood after crushing bulk pharmaceutical chemicals, are uniformly mixed, obtain plant composition；
(2) it is that 60%~95% ethyl alcohol carries out ultrasonic extraction that concentration of volume percent is added into plant composition, is obtained
Ultrasonic extraction liquid；
(3) it is filtered after standing ultrasonic extraction liquid, obtains filtrate；
(4) after addition 1,3-BDO is miscible uniformly in filtrate, the ethyl alcohol in solution is rotated out, is filtered by vacuum, filter is collected
Liquid to get.
In the present invention, it is preferred to, the parts by weight of each bulk pharmaceutical chemicals are in step (1)：Print plus 40~60 parts of fruit, balsamine 40
~60 parts, 20~30 15~30 parts of part, bar denier wood of olea europaea fruit, the crushing are to be crushed to 80~120 mesh；In step (2)
The ratio of plant society amount of substance and 60%~95% ethyl alcohol volume is 1:10~1:30, g/mL；The item of the ultrasonic extraction
Part is：Extracting temperature is 40 DEG C~70 DEG C, and the time is 0.5~2h, and ultrasonic power is 300~500W；The specific steps of step (3)
For：Ultrasonic extraction liquid is stopped heating, ultrasonic extraction liquid is stood 2~4 hours, after the filtering of 100~200 mesh, obtains filtrate；Step
(4) the specific steps are：In filtrate be added with the isometric 1,3-BDO of 60%~95% ethyl alcohol it is miscible uniformly after, rotate out
Ethyl alcohol in solution, vacuum filtration, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Further, the present invention provides a kind of methods preparing the Islamic plant cream, which is characterized in that packet
Include following steps：
(1) butanediol, glycerine and the thickener in B phases are stirred evenly, for use；
(2) metal-chelator in B phases is added in deionized water, is stirring evenly and then adding into step (1) butanediol, glycerine
With the mixture of thickener, 80~85 DEG C are heated to, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~
3000r/min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling,
30~50r/min of stir speed (S.S.), rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product.
Further, the present invention also provides the Islamic plant composition for skin care to prepare with oil-control, remove
Application in free radical and the cosmetics of Red blood streak dispelling effect.
In the preferred embodiment of the invention, it is Islamic plant cream that above-mentioned raw materials and method, which are prepared,.According to making
With approach difference, plant extracts is obtained after Islamic plant composition for skin care of the present invention is extracted, may also be fabricated which other skin
Care formulations, such as creams, essence, shampoo, hair conditioner, but it is not limited to above-mentioned dosage form, it can be according to skin care product industry
A variety of different external preparations are made in known method in field.
The preparation method of plant composition of the present invention is not limited to of the present invention, other in the art conventional methods also may be used
Realize that described effect, the method for the present invention are that inventor recommends preferable preparation method.Plant cream of the present invention is inventor through creating
Property labour obtain optimum formula, be formulated each component between cooperate with work.Raw material and raw material sources used in the present invention are shown in Table
2, product quality and raw material sources meet Islamic standard.
Cream of the present invention recommends method：Daily after cleaning skin, appropriate cream is taken uniformly to be applied to skin,
It is gently massaged into and fully absorbs.
Compared with prior art, beneficial effects of the present invention are embodied in：
Raw material selection natural plant composition of the present invention, non-stimulated to skin safe, plant extracts itself not only has
Free radical and Red blood streak dispelling and other effects are removed in oil-control, also there is moisturizing, slow down aging and other effects.Raw material of the present invention, which obtain, to be held
Easily, preparation method is easy, green safe, is easy to crowd's receiving, has good application prospect and market prospects.
Description of the drawings
Fig. 1 be 3 volunteers laser-Doppler picture before and after comparison diagram, wherein the left figure in Fig. 1 is respectively No. 1,2
Number and 3 st volunteers experiment before laser-Doppler picture, right figure be respectively No. 1, No. 2 and 3 st volunteers experiment after
Laser-Doppler picture；
Fig. 2 is that cream of the present invention removes DPPH free radical testing result figures；
Fig. 3 be using cream of the present invention compared with the change rate of control group test section skin oil and fat content figure；
Fig. 4 be using cream of the present invention compared with the relative change rate of control group test section skin oil and fat content figure；Its
In, *：p<0.05.
Specific implementation mode
The invention will now be further described with reference to specific embodiments, the advantages and features of the present invention will be with description and
It is apparent.But examples are merely exemplary for these, and it is not intended to limit the scope of the present invention in any way.People in the art
Member it should be understood that without departing from the spirit and scope of the invention can to the details of technical solution of the present invention and form into
Row modifications or substitutions, but these modifications and replacement are each fallen in protection scope of the present invention.
Medicinal material used in following embodiment can be commercially available from China Medicament Group Corp., meet the People's Republic of China (PRC)
2005 editions standards of pharmacopeia.Other raw materials can be obtained by commercially available purchase, the instrument title used in the present invention and producer's such as table 1,
The present invention is shown in Table 2. using the source of raw material
Table 1
| Title | Model | Producer |
| Ultraviolet-uisible spectrophotometer | UV2300 | Beijing Pu Xi all purpose instruments Co., Ltd |
| Ultrasonic wave recycles extractor | SCIENTZ-HF5000 | Henan brother's experimental instruments and equipment limited |
| Rotate generator | RE-6000A | Shanghai Yarong Biochemical Instrument Plant |
| Electric ceramic heaters | LC-E013S | Official loyal to his sovereign Electric company |
| Blender | Eurostar strength control type-vica | German IKA companies |
| Dispersion machine | 25 digital displays of T | German IKA companies |
| Oil-control tester | 4K15 | Sigma companies |
| Electronic balance | METTLER ML3002 | Mei Tele companies |
| Doppler flowmeter | PeriScan PIM3 | Pa Rui medical science and technologies company |
Table 2
The preparation of 1 Islamic plant composition for skin care of the present invention of embodiment
Each bulk pharmaceutical chemicals are weighed by following weight：Print plus fruit 60g, balsamine 60g, olea europaea fruit 10g, bar denier wood 20g；It will be upper
It states each bulk pharmaceutical chemicals and is crushed to 120 mesh respectively, be uniformly mixed, obtain plant composition；Volume hundred is added to above-mentioned plant composition
It is that 95% ethyl alcohol 4500ml carries out ultrasonic extraction to divide specific concentration, obtains ultrasonic extraction liquid, and Extracting temperature is 60 DEG C, time 2h,
Ultrasonic power is 500W, and the volume ratio (g/mL) of the quality of the plant composition and 95% ethyl alcohol is 1:30；Stop heating, it will
Ultrasonic extraction liquid stands 4 hours, after 200 mesh screens, obtains filtrate；4500ml 1,3 butylene glycols are added in filtrate (with 95% second
Alcohol is isometric) it is miscible uniformly after, rotate out the ethyl alcohol in solution, be filtered by vacuum, vacuum degree be 0.06~0.1MPa, collect filter
Liquid to get.
The preparation of 2 Islamic plant composition for skin care of the present invention of embodiment
Each bulk pharmaceutical chemicals are weighed by following weight：Print plus fruit 30g, balsamine 30g, olea europaea fruit 25g, bar denier wood 30g；It will be upper
It states each bulk pharmaceutical chemicals and is crushed to 80 mesh respectively, be uniformly mixed, obtain plant composition；Volume basis is added to above-mentioned plant composition
Specific concentration is that 60% ethyl alcohol 1150ml carries out ultrasonic extraction, obtains ultrasonic extraction liquid, and Extracting temperature is 45 DEG C, time 0.5h,
Ultrasonic power is 350W, and the volume ratio (g/mL) of the quality of the plant composition and 60% ethyl alcohol is 1:10；Stop heating, it will
Ultrasonic extraction liquid stands 2 hours, after 100 mesh screens, obtains filtrate；1150ml 1,3 butylene glycols are added in filtrate (with 60% second
Alcohol is isometric) it is miscible uniformly after, rotate out the ethyl alcohol in solution, be filtered by vacuum, vacuum degree be 0.06~0.1MPa, collect filter
Liquid to get.
The preparation of 3 Islamic plant composition for skin care of the present invention of embodiment
Each bulk pharmaceutical chemicals are weighed by following weight：Print plus fruit 50g, balsamine 40g, olea europaea fruit 20g, bar denier wood 25g；It will be upper
It states each bulk pharmaceutical chemicals and is crushed to 80 mesh respectively, be uniformly mixed, obtain plant composition；Volume basis is added to above-mentioned plant composition
Specific concentration is that 85% ethyl alcohol 2700ml carries out ultrasonic extraction, obtains ultrasonic extraction liquid, and Extracting temperature is 70 DEG C, time 1.5h,
Ultrasonic power is 450W, and the volume ratio (g/mL) of the quality of the plant composition and 85% ethyl alcohol is 1:20；Stop heating, it will
Ultrasonic extraction liquid stands 3.5 hours, after 150 mesh screens, obtains filtrate；2700ml 1,3 butylene glycols are added in filtrate (with 85%
Ethyl alcohol is isometric) it is miscible uniformly after, rotate out the ethyl alcohol in solution, be filtered by vacuum, vacuum degree be 0.06~0.1MPa, collect filter
Liquid to get.
The preparation of 4 cream of the present invention of embodiment
Raw material and proportioning (mass percent), are shown in Table 3：
Table 3
The preparation of plant extracts in D phases：
(1) bulk pharmaceutical chemicals are weighed according to following weight parts；
Print plus fruit 50g, balsamine 40g, olea europaea fruit 20g, bar denier wood 25g, are crushed to 80 mesh respectively, are uniformly mixed, obtain
To plant composition；
(2) it is that 85% ethyl alcohol 3375ml carries out ultrasonic extraction that concentration of volume percent is added into above-mentioned plant composition,
Obtain ultrasonic extraction liquid, Extracting temperature is 50 DEG C, time 1h, ultrasonic power 450W, the quality of the plant composition with
The volume ratio (g/mL) of 85% ethyl alcohol is 1:25；
(3) stop heating, ultrasonic extraction liquid prepared by step (2) stands 3.5 hours, after the filtering of 150 mesh, obtains filtrate；
After addition 3375ml 1,3-BDOs (isometric with 85% ethyl alcohol) are miscible uniformly in filtrate, the ethyl alcohol in solution is rotated out, very
Sky filter, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Cream preparation method：
(1) butanediol, glycerine and the xanthans in B phases are stirred evenly, for use；
(2) EDETATE SODIUM in B phases is added in deionized water, be stirring evenly and then adding into step (1) butanediol, glycerine with
The mixture of xanthans is heated to 80~85 DEG C, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~
3000r/min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling,
30~50r/min of stir speed (S.S.), rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product
Cream.
The preparation of 5 cream of the present invention of embodiment
Raw material and proportioning (mass percent), are shown in Table 4：
Table 4
The preparation of plant extracts in D phases：
(1) bulk pharmaceutical chemicals are weighed according to following weight parts；
Print plus fruit 30g, balsamine 30g, olea europaea fruit 25g, bar denier wood 30g；Above-mentioned each bulk pharmaceutical chemicals are crushed to 120 respectively
Mesh is uniformly mixed, obtains plant composition；
(2) it is that 60% ethyl alcohol 1725ml carries out ultrasonic extraction that concentration of volume percent is added into above-mentioned plant composition,
Ultrasonic extraction liquid is obtained, Extracting temperature is 70 DEG C, time 1.5h, ultrasonic power 300W, the quality of the plant composition
Volume ratio (g/mL) with 60% ethyl alcohol is 1:15；
(3) stop heating, ultrasonic extraction liquid prepared by step (2) stands 2 hours, after the filtering of 100 mesh, obtains filtrate；Filter
After 1725ml 1,3-BDOs miscible uniformly (isometric with 60% ethyl alcohol) are added in liquid, the ethyl alcohol in solution, vacuum are rotated out
Filter, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Cream preparation method：
(1) butanediol, glycerine and the xanthans in B phases are stirred evenly, for use；
(2) EDETATE SODIUM in B phases is added in deionized water, be stirring evenly and then adding into step (1) butanediol, glycerine with
The mixture of xanthans is heated to 80~85 DEG C, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~
3000r/min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling,
30~50r/min of stir speed (S.S.), rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product
Cream.
The preparation of 6 cream of the present invention of embodiment
Raw material and proportioning (mass percent), are shown in Table 5：
Table 5
The preparation of plant extracts in D phases：
(1) bulk pharmaceutical chemicals are weighed according to following weight parts；
Print plus fruit 60g, balsamine 60g, olea europaea fruit 10g, bar denier wood 20g；Above-mentioned each bulk pharmaceutical chemicals are crushed to 80 respectively
Mesh is uniformly mixed, obtains plant composition；
(2) it is that 95% ethyl alcohol 3000ml carries out ultrasonic extraction that concentration of volume percent is added into above-mentioned plant composition,
Obtain ultrasonic extraction liquid, Extracting temperature is 40 DEG C, time 2h, ultrasonic power 500W, the quality of the plant composition with
The volume ratio (g/mL) of 95% ethyl alcohol is 1:20；
(3) stop heating, ultrasonic extraction liquid prepared by step (2) stands 4 hours, after the filtering of 200 mesh, obtains filtrate；Filter
After addition 3000ml 1,3-BDOs (isometric with 95% ethyl alcohol) are miscible uniformly in liquid, the ethyl alcohol in solution, vacuum are rotated out
Filter, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Cream preparation method：
(1) butanediol, glycerine and the xanthans in B phases are stirred evenly, for use；
(2) EDETATE SODIUM in B phases is added in deionized water, be stirring evenly and then adding into step (1) butanediol, glycerine with
The mixture of xanthans is heated to 80~85 DEG C, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~
3000r/min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling,
30~50r/min of stir speed (S.S.), rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product
Cream.
The preparation of 7 cream of the present invention of embodiment
Raw material and proportioning (mass percent), are shown in Table 6：
Table 6
The preparation of plant extracts in D phases：
(1) bulk pharmaceutical chemicals are weighed according to following weight parts；
Print plus fruit 45g, balsamine 20g, olea europaea fruit 16g, bar denier wood 14g, are crushed to 100 mesh respectively, are uniformly mixed, obtain
To plant composition；
(2) it is that 80% ethyl alcohol 2850ml carries out ultrasonic extraction that percent by volume is added into above-mentioned plant composition, is obtained
Ultrasonic extraction liquid, Extracting temperature are 65 DEG C, time 2h, ultrasonic power 400W, the quality of the plant composition and 80%
The volume ratio (g/mL) of ethyl alcohol is 1:30；
(3) stop heating, ultrasonic extraction liquid prepared by step (2) stands 3 hours, after the filtering of 100 mesh, obtains filtrate；Filter
After addition 2850ml 1,3-BDOs (isometric with 80% ethyl alcohol) are miscible uniformly in liquid, the ethyl alcohol in solution, vacuum are rotated out
Filter, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
Cream preparation method：
(1) butanediol, glycerine and the xanthans in B phases are stirred evenly, for use；
(2) EDETATE SODIUM in B phases is added in deionized water, be stirring evenly and then adding into step (1) butanediol, glycerine with
The mixture of xanthans is heated to 80~85 DEG C, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~
3000r/min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling,
30~50r/min of stir speed (S.S.), rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product
Cream.
The effect of 1 Islamic plant cream of the present invention of test example, tests
One, Red blood streak dispelling effect
1, experimental principle
Doppler flowmeter
Laser doppler technique is a kind of unique technology of continuous monitoring tissue blood flow.When monochromatic laser beam and blood flow
When the interactions such as the haemocyte of middle movement, according to Doppler effect, reflection light frequency changes, and the increase and decrease of this frequency and changes
The size of variable is related with blood flow direction and flow velocity (quantity for being proportional to the haemocyte in the unit interval by certain vascular cross-section).
Detector on probe is able to detect that these small variations, and storage, analyzing processing in systems, is finally synthesizing reaction
The image of blood circumstance.
2, experiment content
1. choose 30 volunteers cleans face skin using facial cleanser, contain in 22 ± 1 DEG C, 50 ± 5% moisture after clean skin
Sit quietly 20min in the constant-humidity constant-temperature laboratory of amount；
2. measuring the data such as volunteer's background values and picture successively；
3. volunteer is according to the skin care cream respectively prepared using embodiment 4 in the present invention accustomed to using of toner cream
It is 30 days, sooner or later each daily to smear once；
4. using cream after 30 days, volunteer according to background values data method is surveyed, measure again using numerical value after product and
The data such as picture；
5. volunteer fills in related investigation questionnaire according to the effect after using product 30 days, recycling questionnaire simultaneously counts corresponding
Data carry out data analysis；
6. according to data and picture analyzing.
3, interpretation of result
1. 30 parts statistics questionnaire investigations as a result, volunteer can be clearly felt that red blood trace on face amount reduction be 78%,
Red blood silk quantity be reduced but be not it is particularly apparent account for 19%, what red blood silk quantity did not change accounts for 3%.
2. doppler flowmeter data results (take 3 volunteers to test shooting image)
3 volunteers test shooting image and see Fig. 1, wherein the left figure in Fig. 1 is respectively No. 1, No. 2 and 3 st volunteers
Laser-Doppler picture before experiment, right figure be respectively No. 1, No. 2 and 3 st volunteers experiment after (prepared using embodiment 4
After cream 30 days) laser-Doppler picture, black region area is bigger in Fig. 1, shows that blood perfusion amount is lower.According to Fig. 1
Data analysis is carried out, concrete analysis the results are shown in Table 7.
Comparing result before and after 7 volunteer's laser-Doppler picture of table
By Fig. 1 and table 7 it is found that using blood perfusion amount after product of the present invention compared with using being substantially reduced before product, production is used
For skin Average baseline value compared with having reduction before use, this shows that the test sample of the present invention has the work for reducing skin microcirculation after product
With to reduce the effect of visual capillary quantity is to reach Red blood streak dispelling.
Two, free radical effect is removed
1, experimental principle
DPPH (1,1-disphenyl-2-picry1-hydrazy1), chemical name 1,1- diphenyl -2- trinitrobenzens
Hydrazine, molecular formula are (C6H5)2N-NC6H5(NO2)3, there are one not pairs of valence electricity on an atom of nitrogen bridge in this compound
Son, and the movement of the track of this electronics is almost offset by molecular structure, it is usually anti-oxidant as evaluating to capture DPPH free radicals
The index of ability.The reaction mechanism such as following formula of specific DPPH free radicals：
2, laboratory apparatus and sample
Laboratory apparatus：Ultraviolet-uisible spectrophotometer；Assay balance.
Sample：Cream prepared by embodiment 4.
Positive control：Vitamin C (vitamin C is a kind of antioxidant, threat of the protection body from free radical).
0.1g vitamin Cs are taken, water is added to be settled to 100ml, as 0.01% vitamin c solution.
3, experimental method
1) take 1mL prepare liquid and 1mL 2 × 10-4The DPPH solution mixings (A of mol/L1Pipe)；
2) take 1mL absolute ethyl alcohol and 1mL 2 × 10-4The DPPH solution mixings (A of mol/L2Pipe)；
3) absolute ethyl alcohol of 1mL and the prepare liquid mixing (A3 pipes) of 1mL are taken；
4) after reacting 30min, A is surveyed at 517nm1、A2、A3Pipe absorbance value.
Table 8
| Number | DPPH solution | Absolute ethyl alcohol | Cream | Total volume |
| A1 | 1.0mL | —— | 1.0mL | 2mL |
| A2 | 1.0mL | 1.0mL | —— | 2mL |
| A3 | —— | 1.0mL | 1.0mL | 2mL |
4, interpretation of result
Clearance rate calculation formula is：Clearance rate (%)=[(A2+A3)-A1]/A2
Analysis：Wherein positive control is vitamin C.
In effective range, the clearance rate of sample has clearance rate in effective range (0-100%) as seen from Figure 2
There is the effect of removing DPPH free radicals, and bigger, effect is better.
Therefore, sample has the effect of removing DPPH free radicals.
Three, oil-control effect
1, experimental principle
Human experimentation forms test population by particular experiment crowd (Moslem crowd), and test subject uses before cream
The variation of skin oil and fat content afterwards, so that it is determined that suppression fat effect of cosmetics (or functional component).
2, laboratory apparatus and sample
Laboratory apparatus：Skin oil and fat testerSM815。
Laboratory sample：Cream prepared by embodiment 4.
Blank control group：It does not smear any product, secretes grease data and the progress of laboratory sample group by measuring skin
Control, to determine laboratory sample group oil-control effect.
3, Subject Population
Subject amounts to 30 people.Specific sex composition and age composition determine at random.If it is bad anti-that period has 2 people to occur
It answers, then terminates test；As a result adverse reaction is not found.
4, experimental method
1. selecting subject's forehead label.
2. technical staff uses skin oil and fat testerSM815 tests test position 3 times, is averaged,
It is denoted as initial value.
3. subject tries out sample and smears forehead region, other oil-control productions for having oil-control effect cannot be smeared during test
Product.
4. subject is first week after being used continuously cream, after second week, 4th week, skin oil and fat is used by technical staff
TesterSM815 is measured 3 times, is averaged.
5. counting the numerical value measured, its skin oil and fat changes of contents rule is analyzed.
5, result and analysis
Within test period, this test event screens 30 people and is included in research altogether, falls off between no group, and in tested crowd not
There is the skin irritatin of apparent systemic adverse reactions or 3 grades or more, therefore effective volunteer's number of this test is 30 people.
△=Tn-T0
Change rate (%)=((Tn-T0)/T0) × 100, this value is lower, and it is fewer that skin secretes oil quantity at any time.
Relative change rate (%)=(((Tn-T0)-(KTn-KT0))/T0) × 100, this value is lower, illustrates relative comparison
Group, test section skin oil and fat content are fewer.
In formula, Tn --- tested region changes over time numerical value
T0 --- tested region initial value
KTn --- white space changes over time numerical value
KT0 --- white space initial value
The rate of change value of skin oil and fat content and relative change rate see Fig. 3 and Fig. 4.
As seen from Figure 3, within 4 weeks test periods, after subject uses test sample, test section skin oil and fat content
It is in raising trend, but change rate was below control group at the 1st week, the 2nd week and the 4th week, illustrated that test section skin oil and fat contains
Amount is less than control group.
As seen from Figure 4, within 4 weeks test periods, after subject uses test sample, test section skin oil and fat content
Equal relative change rate was negative value at the 1st week, the 2nd week and the 4th week, illustrated test section skin oil and fat content less than control
Group, and there are significant difference (p at the 4th week<0.05), i.e., sample has oil-control effect.
Four, human body patch test
1, test objective
Human trial forms test population by special test crowd (Moslem crowd), and test subject uses cosmetics
(and cosmetic industry ingredient) front and back possibility for causing human skin adverse reaction.
2, test material
Spot tries device：Beijing North cures the production of management of investment Co., Ltd, round, diameter 12mm.
Spot tries object：Cream 0.025g prepared by Example 4.
3, crowd and testing time are tested
Effective subject amounts to 30 people, and determination (meets 2007 at random for specific sex composition and age composition《Cosmetics health
Specification》It is included in, exclusion criteria.
Test the time started：On 07 06th, 2015 on 07 08th, 2015.
4, test method
1. it is 30 to select subject, number by subject enrollment standard.
2. selecting qualified patch material, sample is put into spot examination device (amount of samples is 0.020g~0.025g), control
Hole is blank (not setting any substance).Sample and blank control are affixed on to the forearm song side of subject, is gently pressed and is allowed to palm
It is equably pasted on skin, continues for 24 hours.
3. being spaced 30min after removal patch device, dermoreaction is observed after impression disappearance.
4. observing primary, observation dermoreaction after patch test again respectively with 48h for 24 hours.
5. skin adverse reaction grade scale is shown in Table 9.
9 skin adverse reaction of table is classified
5, test result
Table 10 takes out 0.5 hour observation result of patch device
Table 11 removes 24 hours observation results of spot examination device
Table 12 removes 48 hours observation results of spot examination device
It is explained according to skin closure type patch test results：Occurs the number of 1 grade of skin adverse reaction in 30 subjects
Number more than 5 or 2 grades skin adverse reactions is more than 2, or any 13 grades or 3 grades or more skin adverse reactions occurs
When, judgement tested material has adverse reaction to human body.
Skin closure type patch test results are shown in Table 10,11 and 12, according to the results show that inventive samples to human skin
It has no adverse reaction.Inventor repeats above-mentioned experiment using sample prepared by other embodiment, and test result is with above-mentioned,
It has no adverse reaction to human skin.
Claims (10)
1. a kind of Islamic plant composition for skin care, which is characterized in that be made of the bulk pharmaceutical chemicals of following parts by weight：Print plus fruit 30~60
Part, 20~60 parts of balsamine, 10~30 10~30 parts of part, bar denier wood of olea europaea fruit.
2. Islamic plant composition for skin care according to claim 1, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are：Print
Add 40~60 parts of fruit, 40~60 parts of balsamine, 20~30 15~30 parts of part, bar denier wood of olea europaea fruit.
3. a kind of method preparing Islamic plant composition for skin care as claimed in claim 1 or 2, which is characterized in that including following
Step：
(1) each bulk pharmaceutical chemicals are weighed respectively according to the parts by weight, after bulk pharmaceutical chemicals are crushed, be uniformly mixed, obtain plant society
Object；
(2) it is that 60%~95% ethyl alcohol carries out ultrasonic extraction that concentration of volume percent is added into plant composition, obtains ultrasound
Extracting solution；
(3) it is filtered after standing ultrasonic extraction liquid, obtains filtrate；
(4) after addition 1,3-BDO is miscible uniformly in filtrate, the ethyl alcohol in solution is rotated out, is filtered by vacuum, collects filtrate, i.e.,
.
4. according to the method described in claim 3, it is characterized in that, the crushing described in step (1) is to be crushed to 80~120 mesh；
The ratio of plant society amount of substance and 60%~95% ethyl alcohol volume is 1 in step (2):10~1:30, g/mL；The ultrasound
The condition of extraction is：Extracting temperature is 40 DEG C~70 DEG C, time 0.5-2h, and ultrasonic power is 300~500W；Step (3)
The specific steps are：Ultrasonic extraction liquid is stopped heating, ultrasonic extraction liquid is stood 2~4 hours, after the filtering of 100~200 mesh, is obtained
Filtrate；Step (4) the specific steps are：It is added in filtrate miscible uniformly with the isometric 1,3 butylene glycol of 60%~95% ethyl alcohol
Afterwards, rotate out the ethyl alcohol in solution, be filtered by vacuum, vacuum degree be 0.06~0.1MPa, collect filtrate to get.
5. a kind of Islamic plant cream, which is characterized in that the Islamic plant cream by following weight percent raw material group
At：
Wherein, the plant extracts is the extract according to Islamic plant composition for skin care described in claim 1.
6. Islamic plant cream according to claim 5, which is characterized in that the emulsifier is cetostearyl alcohol/coconut palm
Oil base glucoside；The thickener is xanthans；The skin conditioning agent is the HA solution that mass fraction is 1%；It is described
Metal-chelator be EDETATE SODIUM；The preservative is selected from methyl p-hydroxybenzoate, propylparaben, the third two
Alcohol/methylisothiazolinone/iodine propilolic alcohol butyl mephenesin Carbamate/sodium chloride, Phenoxyethanol/Sensiva SC50 and to hydroxyl
At least one of isobutyl benzoate.
7. Islamic plant cream according to claim 5, which is characterized in that the plant extracts uses following methods
It is prepared：
(1) each bulk pharmaceutical chemicals are weighed according to following weight parts, print plus 30~60 parts of fruit, 20~60 parts of balsamine, olea europaea fruit 10~
30 10~30 parts of part, bar denier wood after crushing bulk pharmaceutical chemicals, are uniformly mixed, obtain plant composition；
(2) it is that 60%~95% ethyl alcohol carries out ultrasonic extraction that concentration of volume percent is added into plant composition, obtains ultrasound
Extracting solution；
(3) it is filtered after standing ultrasonic extraction liquid, obtains filtrate；
(4) after addition 1,3-BDO is miscible uniformly in filtrate, the ethyl alcohol in solution is rotated out, is filtered by vacuum, collects filtrate, i.e.,
.
8. Islamic plant cream according to claim 7, which is characterized in that the parts by weight of each bulk pharmaceutical chemicals are in step (1)：
Print plus 40~60 parts of fruit, 40~60 parts of balsamine, 20~30 15~30 parts of part, bar denier wood of olea europaea fruit, the crushing are powder
It is broken to 80~120 mesh；The ratio of plant society amount of substance and 60%~95% ethyl alcohol volume is 1 in step (2):10~1:30,
g/mL；The condition of the ultrasonic extraction is：Extracting temperature is 40 DEG C~70 DEG C, and the time is 0.5~2h, ultrasonic power 300
~500W；Step (3) the specific steps are：Ultrasonic extraction liquid is stopped heating, ultrasonic extraction liquid is stood 2~4 hours, 100
After the filtering of~200 mesh, filtrate is obtained；Step (4) the specific steps are：1 isometric with 60%~95% ethyl alcohol is added in filtrate,
3- butanediols it is miscible uniformly after, rotate out the ethyl alcohol in solution, be filtered by vacuum, vacuum degree be 0.06~0.1MPa, collect filtrate,
To obtain the final product.
9. a kind of method of the Islamic plant cream prepared described in claim 5, which is characterized in that include the following steps：
(1) butanediol, glycerine and the thickener in B phases are stirred evenly, for use；
(2) metal-chelator in B phases is added in deionized water, is stirring evenly and then adding into step (1) butanediol, glycerine and increasing
Thick dose of mixture is heated to 80~85 DEG C, mixing；
(3) A phase raw materials are weighed successively, are heated to 80~85 DEG C, mixing；
(4) the A phases raw material of step (3) mixing is all added in the B phase raw materials of step (2) mixing, 2000~3000r/
Min, 5~10min of homogeneous；C phase raw materials are added, 4000~5000r/min, 1~3min of homogeneous start stirring cooling, stirring speed
30~50r/min of rate, rate of temperature fall are 1~2 DEG C/min；
(5) when temperature drops to 45~50 DEG C, D phase raw materials is added, stir evenly；
(6) when temperature drops to 40~45 DEG C, E phase raw materials are added, stirs evenly, continues to be cooled to 40 DEG C hereinafter, to obtain the final product.
10. Islamic plant composition for skin care as claimed in claim 1 or 2 is preparing with oil-control, is removing free radical and red blood of dispelling
Application in the cosmetics of silk effect.
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| CN106420419A (en) * | 2016-11-02 | 2017-02-22 | 珍尔姿（广州）化妆品有限公司 | Inca inch containing functional skin-care product |
| CN108245454B (en) * | 2018-02-26 | 2020-12-04 | 广州丽丰化妆品制造有限公司 | Mild cleansing cream containing natural antioxidant components and preparation method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030170331A1 (en) * | 2000-04-28 | 2003-09-11 | Marie-Madeleine Cals-Grierson | Plant extract of the olea europaea as no-synthase inhibitor and uses |
| FR2880278A1 (en) * | 2005-01-05 | 2006-07-07 | Greentech Sa Sa | USE OF OIL AND PROTEINS EXTRACTED FROM PLUKENETIA VOLUBILIS LINNEO SEEDS IN COSMETIC, DERMATOLOGICAL AND NUTRACEUTICAL PREPARATIONS |
| CN101978942A (en) * | 2010-10-27 | 2011-02-23 | 中国科学院西双版纳热带植物园 | A kind of Omega-3 fatty acid oil skin care lotion and preparation method thereof |
| CN101982163A (en) * | 2010-10-27 | 2011-03-02 | 中国科学院西双版纳热带植物园 | Omega-3 fatty acid oil body lotion and preparation method thereof |
| KR101252560B1 (en) * | 2006-11-30 | 2013-04-08 | (주)아모레퍼시픽 | Cosmetic composition containing extracts of Impatiens balsamina L. for controlling anti-acne or anti-comedone |
| US20140348873A1 (en) * | 2013-05-22 | 2014-11-27 | Professional Compounding Centers Of America | Urea-Silicone Gel for Hyperkeratosis Treatment |
| CN104382980A (en) * | 2014-11-14 | 2015-03-04 | 中国科学院西双版纳热带植物园 | Plukenetia volubilis L. stem leaf extract capable of delaying senescence as well as preparation method and application of extract |
| CN104825366A (en) * | 2015-05-25 | 2015-08-12 | 三亚啓星生物能源发展有限公司 | Plukenetia volubilis linneo body lotion and preparation method thereof |
-
2015
- 2015-09-15 CN CN201510587653.9A patent/CN105147555B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030170331A1 (en) * | 2000-04-28 | 2003-09-11 | Marie-Madeleine Cals-Grierson | Plant extract of the olea europaea as no-synthase inhibitor and uses |
| FR2880278A1 (en) * | 2005-01-05 | 2006-07-07 | Greentech Sa Sa | USE OF OIL AND PROTEINS EXTRACTED FROM PLUKENETIA VOLUBILIS LINNEO SEEDS IN COSMETIC, DERMATOLOGICAL AND NUTRACEUTICAL PREPARATIONS |
| KR101252560B1 (en) * | 2006-11-30 | 2013-04-08 | (주)아모레퍼시픽 | Cosmetic composition containing extracts of Impatiens balsamina L. for controlling anti-acne or anti-comedone |
| CN101978942A (en) * | 2010-10-27 | 2011-02-23 | 中国科学院西双版纳热带植物园 | A kind of Omega-3 fatty acid oil skin care lotion and preparation method thereof |
| CN101982163A (en) * | 2010-10-27 | 2011-03-02 | 中国科学院西双版纳热带植物园 | Omega-3 fatty acid oil body lotion and preparation method thereof |
| US20140348873A1 (en) * | 2013-05-22 | 2014-11-27 | Professional Compounding Centers Of America | Urea-Silicone Gel for Hyperkeratosis Treatment |
| CN104382980A (en) * | 2014-11-14 | 2015-03-04 | 中国科学院西双版纳热带植物园 | Plukenetia volubilis L. stem leaf extract capable of delaying senescence as well as preparation method and application of extract |
| CN104825366A (en) * | 2015-05-25 | 2015-08-12 | 三亚啓星生物能源发展有限公司 | Plukenetia volubilis linneo body lotion and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| les fleurs de Bach巴赫复方青少年花精 Organic;巴赫花精;《https://www.douban.com/doulist/27725831/》;20140902;第2页 * |
| 印加果油——来自亚马逊的神奇植物;无;《http://bbs.hh.cn/forum.php?mod=viewthread&tid=147141》;20130419 * |
| 推荐6款超好用天然护肤品！远离刺激皮肤的化学成分！;sourpanda;《http://9night.kimiss.com/thread-1431083-1-1.html》;20141227;第4-5页 * |
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