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CN105079577A - Traditional Chinese medicine composition for treating hypertension and preparing method thereof - Google Patents

Traditional Chinese medicine composition for treating hypertension and preparing method thereof Download PDF

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CN105079577A
CN105079577A CN201510611968.2A CN201510611968A CN105079577A CN 105079577 A CN105079577 A CN 105079577A CN 201510611968 A CN201510611968 A CN 201510611968A CN 105079577 A CN105079577 A CN 105079577A
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radix
herba
fructus
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谢志明
谢侯吉
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Abstract

The invention relates to traditional Chinese medicine for treating hypertension. The traditional Chinese medicine comprises radix notoginseng, American ginseng, tortoise plastron, lucid ganoderma, apocynum venetum, gastrodia elata, coreopsis tinctoria flowers, polygonum multiflorum, eucommia ulmoides and the like. The traditional Chinese medicine composition has the effects of effectively reducing blood fat, softening blood vessels, removing in-vivo waste, improving the immunity of the human body, preventing angiosclerosis, delaying senescence and the like, and the hypertension is avoided. The traditional Chinese medicine mainly has the special curative effects on a coronary heart disease, the hypertension, hyperlipidemia, hyperglycemia and chronic heart and cerebral vessel diseases.

Description

One treats hypertensive Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to field of medicaments, relate in particular to one and treat hypertensive Chinese medicine composition and preparation method thereof.
Background technology
Hypertension is common clinical, and main manifestations is systolic pressure >=140mmHg or diastolic pressure >=90mmHg, and state of an illness long-run development can cause the grievous injury of the target organs such as the heart, brain, kidney, causes the diseases such as coronary heart disease, apoplexy, renal failure.Hypertensive symptom varies with each individual.Early stage possibility is asymptomatic or symptom is not obvious, and blood pressure can occur after fatigue, psychentonia, anxious state of mind and raise, after having a rest, recovery is normal.Along with the course of disease extends, blood pressure significantly continues to raise, there will be various symptom gradually and be benign hypertension, benign hypertension common clinical symptoms has headache, dizziness, absent minded, hypomnesis, numb limbs and tense tendons, nocturia increase, cardiopalmus, uncomfortable in chest, weak etc.Severe headache, vomiting, cardiopalmus, the symptom such as dizzy is there will be when blood pressure is elevated to a certain degree suddenly, obnubilation, tic can be there is time serious, this just belongs to accelerated hypertension and hypertension critical illness, how can there is infringement and the pathological changes of the organs such as the serious heart, brain, kidney in a short time, as apoplexy, heart infarction, renal failure etc.Symptom there is no consistent relation with the level that blood pressure raises.Current western medical treatment hypertension still needs to take medicine all the life, but easily occurs the situations such as drug resistance, target organ damage and fluctuation of blood pressure.Hypertension with traditional Chinese Medical is dialectical belongs to the category such as " dizzy ", " headache ", is that raw in, wind-fire not normal by internal organs imbalance of YIN and YANG, disharmony between QI and blood, ascending or descending movement of vital Qi, the expectorant stasis of blood is handed over caused by resistance.Its disease located in liver, kidney, relevant with the heart, spleen; Characteristic of disease is deficiency in origin and excess in superficiality, empty at liver, kidney, tangible wind, fire, expectorant, gas, the stasis of blood etc.In Hypertension research field, Chinese medicine has unique theoretical system, emphasizes determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, treatment must aim at the pathogenesis of disease, and have the advantages such as blood pressure lowering is steadily eased up, patient compliance is good, clinic is applied.
Summary of the invention
The object of this invention is to provide one and treat hypertensive Chinese medicine composition.
In order to realize object of the present invention, the invention provides one and treat hypertensive Chinese medicine, it is made up of the material of following weight portion:
First compositions, comprise: Radix Notoginseng 30-50 part, Radix Panacis Quinquefolii 60-100 part, Carapax et Plastrum Testudinis 30-65 part, Ganoderma 30-60 part, Herba Apocyni veneti 60-100 part, Rhizoma Gastrodiae 20-35 part, the Kunlun snow chrysanthemum 60-100 part, Radix Polygoni Multiflori 50-80 part, Cortex Eucommiae 60-100 part, Radix Rehmanniae 60-100 part, Fructus Lycii 60-100 part, Fructus Mori 60-100 part, Radix Paeoniae Alba 30-65 part, Radix Salviae Miltiorrhizae 60-100 part, Fructus Crataegi 30-80 part, Fructus Trichosanthis 30-80 part, Spica Prunellae 50-80 part, Radix Scrophulariae 30-65 part, Radix Ophiopogonis 30-80 part, Flos Chrysanthemi 30-80 part, Radix Gentianae 20-35 part, Herba Leonuri 30-50 part, Herba Bidentis Bipinnatae 30-80 part, Rhizoma Alismatis 20-35 part, Radix Aucklandiae 20-35 part, Radix Puerariae 30-65 part, Ramulus Mori 30-65 part, Flos Carthami 20-35 part, Herba Menthae 30-50 part, Fructus Ligustri Lucidi 30-80 part, Herba Ecliptae 30-65 part, Rhizoma Chuanxiong 30-65 part, Radix Cyathulae 30-50 part, Cortex Lycii 30-50 part, Folium Nelumbinis 30-80 part, Flos Sophorae 30-50 part and Semen Cassiae 30-65 part,
Second compositions, comprises: Radix Panacis Quinquefolii 10-25 part, Radix Notoginseng 10-25 part, Radix Angelicae Sinensis 30-50 part, Carapax et Plastrum Testudinis 30-65 part, Concha Ostreae 60-120 part, Ganoderma 60-100 part, Radix Polygoni Multiflori 50-80 part, Herba Taxilli 60-100 part, Cortex Eucommiae 60-100 part, Radix Rehmanniae 60-100 part, Fructus Lycii 60-100 part, Fructus Mori 60-100 part, Radix Paeoniae Alba 30-65 part, Radix Salviae Miltiorrhizae 60-100 part, Fructus Crataegi 30-80 part, Fructus Trichosanthis 30-80 part, Spica Prunellae 30-80 part, Radix Scrophulariae 30-65 part, Radix Ophiopogonis 30-80 part, Flos Chrysanthemi 30-80 part, Radix Gentianae 320 parts, Herba Apocyni veneti 60-100 part, Rhizoma Gastrodiae 20-35 part, Herba Leonuri 30-50 part, Herba Bidentis Bipinnatae 120-200 part, Rhizoma Alismatis 30-65 part, Radix Aucklandiae 30-65 part, Radix Puerariae 30-65 part, Ramulus Mori 30-65 part, Flos Carthami 20-35 part, Herba Menthae 30-50 part, Fructus Ligustri Lucidi 30-80 part, Herba Ecliptae 30-65 part, Rhizoma Chuanxiong 30-65 part, Radix Cyathulae 30-500 part, Cortex Lycii 30-50 part, Folium Nelumbinis 30-80 part, Flos Sophorae 30-80 part, Semen Cassiae 30-65 part, Stigma Maydis 10-30 part, Ramulus Uncariae Cum Uncis 60-100 part, the Kunlun snow chrysanthemum 120-200 part and raw Bulbus Allii Cepae 60-100 part.
Preferably, the hypertensive Chinese medicine for the treatment of of the present invention is made up of the material of following weight portion:
First compositions, comprise: Radix Notoginseng 40 parts, Radix Panacis Quinquefolii 80 parts, Carapax et Plastrum Testudinis 45 parts, Ganoderma 40 parts, Herba Apocyni veneti 80 parts, 25 parts, Rhizoma Gastrodiae, the Kunlun snow chrysanthemum 80 parts, Radix Polygoni Multiflori 60 parts, the Cortex Eucommiae 80 parts, 80 parts, the Radix Rehmanniae, Fructus Lycii 80 parts, Fructus Mori 80 parts, the Radix Paeoniae Alba 40 parts, Radix Salviae Miltiorrhizae 80 parts, Fructus Crataegi 50 parts, Fructus Trichosanthis 50 parts, Spica Prunellae 60 parts, Radix Scrophulariae 40 parts, Radix Ophiopogonis 50 parts, Flos Chrysanthemi 50 parts, Radix Gentianae 25 parts, Herba Leonuri 40 parts, Herba Bidentis Bipinnatae 50 parts, Rhizoma Alismatis 25 parts, the Radix Aucklandiae 25 parts, Radix Puerariae 40 parts, Ramulus Mori 40 parts, 25 parts, Flos Carthami, Herba Menthae 40 parts, Fructus Ligustri Lucidi 50 parts, Herba Ecliptae 40 parts, Rhizoma Chuanxiong 40 parts, Radix Cyathulae 40 parts, Cortex Lycii 40 parts, 50 parts, Folium Nelumbinis, 40 parts, Flos Sophorae and Semen Cassiae 40 parts,
Second compositions, comprise: Radix Panacis Quinquefolii 20 parts, Radix Notoginseng 20 parts, Radix Angelicae Sinensis 40 parts, Carapax et Plastrum Testudinis 40 parts, Concha Ostreae 80 parts, Ganoderma 80 parts, Radix Polygoni Multiflori 60 parts, Herba Taxilli 80 parts, the Cortex Eucommiae 80 parts, 80 parts, the Radix Rehmanniae, Fructus Lycii 80 parts, Fructus Mori 80 parts, the Radix Paeoniae Alba 40 parts, Radix Salviae Miltiorrhizae 80 parts, Fructus Crataegi 50 parts, Fructus Trichosanthis 50 parts, Spica Prunellae 50 parts, Radix Scrophulariae 40 parts, Radix Ophiopogonis 50 parts, Flos Chrysanthemi 50 parts, Radix Gentianae 320 parts, Herba Apocyni veneti 80 parts, 25 parts, Rhizoma Gastrodiae, Herba Leonuri 40 parts, Herba Bidentis Bipinnatae 150 parts, Rhizoma Alismatis 40 parts, the Radix Aucklandiae 40 parts, Radix Puerariae 40 parts, Ramulus Mori 40 parts, 25 parts, Flos Carthami, Herba Menthae 40 parts, Fructus Ligustri Lucidi 50 parts, Herba Ecliptae 40 parts, Rhizoma Chuanxiong 40 parts, Radix Cyathulae 400 parts, Cortex Lycii 40 parts, 50 parts, Folium Nelumbinis, 50 parts, Flos Sophorae, Semen Cassiae 40 parts, Stigma Maydis 20 parts, Ramulus Uncariae Cum Uncis 80 parts, the Kunlun snow chrysanthemum 150 parts and raw Bulbus Allii Cepae 80 parts.
More preferably, described first compositions can be tablet, dispersible tablet, capsule, unguentum or decoction.
More preferably, described second compositions can be tablet, dispersible tablet, capsule, unguentum or decoction.
The present invention also provides a kind of preparation method for the treatment of hypertensive Chinese medicine, and the method comprises:
1) the second compositions is taken: Radix Panacis Quinquefolii 20 grams, Radix Notoginseng 20 grams, Radix Angelicae Sinensis 40 grams, Carapax et Plastrum Testudinis 40 grams, Concha Ostreae 80 grams, Ganoderma 80 grams, Radix Polygoni Multiflori 60 grams, Herba Taxilli 80 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 50 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 320 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 150 grams, Rhizoma Alismatis 40 grams, the Radix Aucklandiae 40 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 400 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 50 grams, Flos Sophorae, Semen Cassiae 40 grams, Stigma Maydis 20 grams, Ramulus Uncariae Cum Uncis 80 grams, the Kunlun snow chrysanthemum 150 grams and raw Bulbus Allii Cepae 80 grams, add 10 premium on currency, heat 3 hours under the condition of reflux, be cooled to room temperature, filter, obtain filtrate,
2) the first compositions is taken: Radix Notoginseng 40 grams, Radix Panacis Quinquefolii 80 grams, Carapax et Plastrum Testudinis 45 grams, Ganoderma 40 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, the Kunlun snow chrysanthemum 80 grams, Radix Polygoni Multiflori 60 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 60 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 25 grams, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 50 grams, Rhizoma Alismatis 25 grams, the Radix Aucklandiae 25 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 40 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 40 grams, Flos Sophorae and Semen Cassiae 40 grams, pulverize, cross 100 mesh sieves, add in above-mentioned filtrate, stir, be evaporated to dry, pulverize, cross 80 mesh sieves, obtain.
Compound recipe adopts Radix Panacis Quinquefolii QI invigorating, Radix Notoginseng is enriched blood, both share activating qi and collateral, can arrhythmia, resist myocardial ischemia, anti-cardiac muscle oxidation, strengthening cardiac contractility ability, blood pressure can be regulated, effectively can reduce temporary and persistency blood pressure, contribute to the recovery of the diseases such as hypertension, arrhythmia, coronary heart disease, acute myocardial infarction, cerebral thrombosis.Be equipped with Carapax Et Plastrum Testudinis YIN nourishing and press down sun, Concha Ostreae helps diformazan to stabilize the yang-energy of high Sheng, add Ganoderma, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Radix Puerariae, Herba Taxilli, Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Radix Rehmanniae invigorating the liver and kidney, defying age, Radix Salviae Miltiorrhizae, Herba Leonuri, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Flos Carthami, Radix Notoginseng, Fructus Trichosanthis shell etc. have invigorates blood circulation, anticoagulant, improves lectin from hemolymph, suppresses proliferation of fibrous tissue, prevents the effects such as GAS.In side, Radix Polygoni Multiflori, Fructus Ligustri Lucidi, Fructus Lycii, Fructus Mori, Rhizoma Alismatis, Semen Cassiae, Fructus Crataegi etc. have effect for reducing blood fat, prevent arteriosclerosis.The antioxidation such as Radix Angelicae Sinensis, Radix Polygoni Multiflori, Fructus Crataegi, Radix Rehmanniae, Radix Salviae Miltiorrhizae, thus reduce free radical, play the effect of protection endotheliocyte.The Cortex Eucommiae, Radix Polygoni Multiflori, the Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Fructus Crataegi, Rhizoma Alismatis, the Radix Aucklandiae, Fructus Ligustri Lucidi, Herba Ecliptae etc. not only have good hypotensive effect, and can diastole efferent glomerular arteriole, reduce glomerule intrinsic pressure, reduce albuminuria, renal function protecting.Rhizoma Gastrodiae, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Gentianae, Ramulus Uncariae Cum Uncis, Herba Leonuri, Herba Bidentis Bipinnatae, Herba Apocyni veneti, Fructus Crataegi, Semen Cassiae has vasorelaxation action, effectively suppress the rising of cholesterol, reduce cholesterol in intestinal absorption, prevent cholesterol from depositing in the tissue, alleviate atherosclerotic formation, can blood pressure lowering, also help and prevent sclerosis of blood vessels, allocate into containing PG-lm and the Bulbus Allii Cepae that blood yield of fibrinolytic enzyme can be activated, for stronger vasodilation, the resistance of peripheral blood vessel and heart coronary artery can be reduced, to the effect of the hypertensive substances such as catecholamine in human body, the excretion of sodium salt can be promoted again, thus make blood pressure drops.To the more aobvious special effect of the cardiovascular patient such as hyperlipidemia, hypertension.
Make a general survey of the hypertensive Chinese medicine compound for the treatment of with enriching yin and nourishing kidney, suppressing the hyperactive liver and subsiding YANG is rule for the treatment of, has special efficacy to relief of symptoms, stabilizing blood pressure.Compound recipe while improving symptom, to playing a protective role of the target organs such as the heart, brain, kidney, can blood pressure lowering, also help simultaneously and prevent sclerosis of blood vessels, reduce incidence rate and the death of hypertension target organ heart kidney complication.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment Chinese medicine powder of the present invention
1) the second compositions is taken: Radix Panacis Quinquefolii 20 grams, Radix Notoginseng 20 grams, Radix Angelicae Sinensis 40 grams, Carapax et Plastrum Testudinis 40 grams, Concha Ostreae 80 grams, Ganoderma 80 grams, Radix Polygoni Multiflori 60 grams, Herba Taxilli 80 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 50 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 320 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 150 grams, Rhizoma Alismatis 40 grams, the Radix Aucklandiae 40 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 400 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 50 grams, Flos Sophorae, Semen Cassiae 40 grams, Stigma Maydis 20 grams, Ramulus Uncariae Cum Uncis 80 grams, the Kunlun snow chrysanthemum 150 grams and raw Bulbus Allii Cepae 80 grams, add 10 premium on currency, heat 3 hours under the condition of reflux, be cooled to room temperature, filter, obtain filtrate,
2) the first compositions is taken: Radix Notoginseng 40 grams, Radix Panacis Quinquefolii 80 grams, Carapax et Plastrum Testudinis 45 grams, Ganoderma 40 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, the Kunlun snow chrysanthemum 80 grams, Radix Polygoni Multiflori 60 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 60 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 25 grams, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 50 grams, Rhizoma Alismatis 25 grams, the Radix Aucklandiae 25 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 40 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 40 grams, Flos Sophorae and Semen Cassiae 40 grams, pulverize, cross 100 mesh sieves, add in above-mentioned filtrate, stir, be evaporated to dry, pulverize, cross 80 mesh sieves, obtain.
Experimental example
Diagnostic criteria
Reference 2002 " new Chinese medicine guideline of clinical investigations " (Zheng Xiao cornel is edited. new Chinese medicine guideline of clinical investigations [S]. and the 1st edition Beijing: China Medical Science Press, 200269-73.) formulate.Dialectical genus heart blood silt: main symptom: chest pain or breast vexed; Secondary card: painful area is fixing not to be moved, pain is drawn inside the shoulder back of the body or arm, palpitation and uneasiness, and lip is purple dark; Picture of the tongue: purplish tongue or have ecchymosis; Pulse condition: hesitant pulse.Have one of main symptom, secondary card has more than 2 or 2 persons, in conjunction with tongue arteries and veins and diagnosable.
The Treating Patients of Angina Pectoris that 68 examples are made a definite diagnosis.Be divided into two groups, treatment group 1 and treatment group 2, in treatment group 1 36 example, male 18 example, women 18 example, age 43-61 year, 53 years old mean age; The course of disease 2 months-2 years, average 1.5 years; Wherein stable angina pectoris 16 example, unstable angina pectoris 20 example.In treatment group 2 32 example, male 16 example, women 16 example, age 42-61 year, average 51 years old; The course of disease 6 months-2 years, average 1.6 years.Wherein stable angina pectoris 16 example, unstable angina pectoris 16 example.Get rid of acute myocardial infarction, the heart disease of other types, gestation and women breast-feeding their children, hepatic and kidney function obstacle patient.Two groups of ages, sex, angina pectoris type and there was no significant differences such as the order of severity, the course of disease (P > 0.05), have comparability.
Treatment group 1 uses Salvia Miltiorrhiza Oral Liquid (Tai Ji, the accurate word Z20063746 of traditional Chinese medicines, every day twice, oral a bottle at every turn), continuously treatment 3 months.
Treatment group 2 uses the powder prepared in embodiment to treat, every day twice, oral 5 grams at every turn, continuously treatment 3 months.
Observation index
Observe angina pectoris attacks number of times, degree, persistent period and other symptom variation before and after treatment; Detect electrocardiogram, blood fat, blood glucose, routine blood test, routine urinalysis, hepatic and renal function before and after treatment, and observe adverse effect.
Criterion of therapeutical effect
According to (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations the 1st volume of [S] 1993:41-45.) formulate.Effective: equal tired degree does not cause uncomfortable in chest, angina pectoris or angina pectoris attacks number of times to be less than more than 80%.Effective: uncomfortable in chest, angina pectoris attacks number of times reduces 50%-80%.Invalid: uncomfortable in chest, angina pectoris attacks number of times reduces less than 50%.
Statistical method
Utilize SPSS13.0 software to process and analyze to experimental data, measurement data is with mean ± standard deviation represent, adopt t inspection, enumeration data adopts x 2inspection, P < 0.05 represents that difference has statistical significance.
Result
Through treatment, for treatment group 1, effective 11 examples, effective 20 examples, invalid 5 examples, total effective rate is 86.1%, and for treatment group 2, effective 19 examples, effective 11 examples, invalid 2 examples, total effective rate is 93.8%.Two groups of total effective rate comparing differences have statistical significance (P < 0.05).Two groups treatments period hematuria is conventional, hepatic and renal function detection is without exception, does not find obvious untoward reaction.

Claims (5)

1. treat a hypertensive Chinese medicine, it is characterized in that, it is made up of the material of following weight portion:
First compositions, comprise: Radix Notoginseng 30-50 part, Radix Panacis Quinquefolii 60-100 part, Carapax et Plastrum Testudinis 30-65 part, Ganoderma 30-60 part, Herba Apocyni veneti 60-100 part, Rhizoma Gastrodiae 20-35 part, the Kunlun snow chrysanthemum 60-100 part, Radix Polygoni Multiflori 50-80 part, Cortex Eucommiae 60-100 part, Radix Rehmanniae 60-100 part, Fructus Lycii 60-100 part, Fructus Mori 60-100 part, Radix Paeoniae Alba 30-65 part, Radix Salviae Miltiorrhizae 60-100 part, Fructus Crataegi 30-80 part, Fructus Trichosanthis 30-80 part, Spica Prunellae 50-80 part, Radix Scrophulariae 30-65 part, Radix Ophiopogonis 30-80 part, Flos Chrysanthemi 30-80 part, Radix Gentianae 20-35 part, Herba Leonuri 30-50 part, Herba Bidentis Bipinnatae 30-80 part, Rhizoma Alismatis 20-35 part, Radix Aucklandiae 20-35 part, Radix Puerariae 30-65 part, Ramulus Mori 30-65 part, Flos Carthami 20-35 part, Herba Menthae 30-50 part, Fructus Ligustri Lucidi 30-80 part, Herba Ecliptae 30-65 part, Rhizoma Chuanxiong 30-65 part, Radix Cyathulae 30-50 part, Cortex Lycii 30-50 part, Folium Nelumbinis 30-80 part, Flos Sophorae 30-50 part and Semen Cassiae 30-65 part,
Second compositions, comprises: Radix Panacis Quinquefolii 10-25 part, Radix Notoginseng 10-25 part, Radix Angelicae Sinensis 30-50 part, Carapax et Plastrum Testudinis 30-65 part, Concha Ostreae 60-120 part, Ganoderma 60-100 part, Radix Polygoni Multiflori 50-80 part, Herba Taxilli 60-100 part, Cortex Eucommiae 60-100 part, Radix Rehmanniae 60-100 part, Fructus Lycii 60-100 part, Fructus Mori 60-100 part, Radix Paeoniae Alba 30-65 part, Radix Salviae Miltiorrhizae 60-100 part, Fructus Crataegi 30-80 part, Fructus Trichosanthis 30-80 part, Spica Prunellae 30-80 part, Radix Scrophulariae 30-65 part, Radix Ophiopogonis 30-80 part, Flos Chrysanthemi 30-80 part, Radix Gentianae 320 parts, Herba Apocyni veneti 60-100 part, Rhizoma Gastrodiae 20-35 part, Herba Leonuri 30-50 part, Herba Bidentis Bipinnatae 120-200 part, Rhizoma Alismatis 30-65 part, Radix Aucklandiae 30-65 part, Radix Puerariae 30-65 part, Ramulus Mori 30-65 part, Flos Carthami 20-35 part, Herba Menthae 30-50 part, Fructus Ligustri Lucidi 30-80 part, Herba Ecliptae 30-65 part, Rhizoma Chuanxiong 30-65 part, Radix Cyathulae 30-500 part, Cortex Lycii 30-50 part, Folium Nelumbinis 30-80 part, Flos Sophorae 30-80 part, Semen Cassiae 30-65 part, Stigma Maydis 10-30 part, Ramulus Uncariae Cum Uncis 60-100 part, the Kunlun snow chrysanthemum 120-200 part and raw Bulbus Allii Cepae 60-100 part.
2. the hypertensive Chinese medicine for the treatment of according to claim 1, is characterized in that, it is made up of the material of following weight portion:
First compositions, comprise: Radix Notoginseng 40 parts, Radix Panacis Quinquefolii 80 parts, Carapax et Plastrum Testudinis 45 parts, Ganoderma 40 parts, Herba Apocyni veneti 80 parts, 25 parts, Rhizoma Gastrodiae, the Kunlun snow chrysanthemum 80 parts, Radix Polygoni Multiflori 60 parts, the Cortex Eucommiae 80 parts, 80 parts, the Radix Rehmanniae, Fructus Lycii 80 parts, Fructus Mori 80 parts, the Radix Paeoniae Alba 40 parts, Radix Salviae Miltiorrhizae 80 parts, Fructus Crataegi 50 parts, Fructus Trichosanthis 50 parts, Spica Prunellae 60 parts, Radix Scrophulariae 40 parts, Radix Ophiopogonis 50 parts, Flos Chrysanthemi 50 parts, Radix Gentianae 25 parts, Herba Leonuri 40 parts, Herba Bidentis Bipinnatae 50 parts, Rhizoma Alismatis 25 parts, the Radix Aucklandiae 25 parts, Radix Puerariae 40 parts, Ramulus Mori 40 parts, 25 parts, Flos Carthami, Herba Menthae 40 parts, Fructus Ligustri Lucidi 50 parts, Herba Ecliptae 40 parts, Rhizoma Chuanxiong 40 parts, Radix Cyathulae 40 parts, Cortex Lycii 40 parts, 50 parts, Folium Nelumbinis, 40 parts, Flos Sophorae and Semen Cassiae 40 parts,
Second compositions, comprise: Radix Panacis Quinquefolii 20 parts, Radix Notoginseng 20 parts, Radix Angelicae Sinensis 40 parts, Carapax et Plastrum Testudinis 40 parts, Concha Ostreae 80 parts, Ganoderma 80 parts, Radix Polygoni Multiflori 60 parts, Herba Taxilli 80 parts, the Cortex Eucommiae 80 parts, 80 parts, the Radix Rehmanniae, Fructus Lycii 80 parts, Fructus Mori 80 parts, the Radix Paeoniae Alba 40 parts, Radix Salviae Miltiorrhizae 80 parts, Fructus Crataegi 50 parts, Fructus Trichosanthis 50 parts, Spica Prunellae 50 parts, Radix Scrophulariae 40 parts, Radix Ophiopogonis 50 parts, Flos Chrysanthemi 50 parts, Radix Gentianae 320 parts, Herba Apocyni veneti 80 parts, 25 parts, Rhizoma Gastrodiae, Herba Leonuri 40 parts, Herba Bidentis Bipinnatae 150 parts, Rhizoma Alismatis 40 parts, the Radix Aucklandiae 40 parts, Radix Puerariae 40 parts, Ramulus Mori 40 parts, 25 parts, Flos Carthami, Herba Menthae 40 parts, Fructus Ligustri Lucidi 50 parts, Herba Ecliptae 40 parts, Rhizoma Chuanxiong 40 parts, Radix Cyathulae 400 parts, Cortex Lycii 40 parts, 50 parts, Folium Nelumbinis, 50 parts, Flos Sophorae, Semen Cassiae 40 parts, Stigma Maydis 20 parts, Ramulus Uncariae Cum Uncis 80 parts, the Kunlun snow chrysanthemum 150 parts and raw Bulbus Allii Cepae 80 parts.
3. the hypertensive Chinese medicine for the treatment of according to claim 1 and 2, is characterized in that, described first compositions can be tablet, dispersible tablet, capsule, unguentum or decoction.
4. the hypertensive Chinese medicine for the treatment of according to claim 1 and 2, is characterized in that, described second compositions can be tablet, dispersible tablet, capsule, unguentum or decoction.
5. treat a preparation method for hypertensive Chinese medicine, the method comprises:
1) the second compositions is taken: Radix Panacis Quinquefolii 20 grams, Radix Notoginseng 20 grams, Radix Angelicae Sinensis 40 grams, Carapax et Plastrum Testudinis 40 grams, Concha Ostreae 80 grams, Ganoderma 80 grams, Radix Polygoni Multiflori 60 grams, Herba Taxilli 80 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 50 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 320 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 150 grams, Rhizoma Alismatis 40 grams, the Radix Aucklandiae 40 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 400 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 50 grams, Flos Sophorae, Semen Cassiae 40 grams, Stigma Maydis 20 grams, Ramulus Uncariae Cum Uncis 80 grams, the Kunlun snow chrysanthemum 150 grams and raw Bulbus Allii Cepae 80 grams, add 10 premium on currency, heat 3 hours under the condition of reflux, be cooled to room temperature, filter, obtain filtrate,
2) the first compositions is taken: Radix Notoginseng 40 grams, Radix Panacis Quinquefolii 80 grams, Carapax et Plastrum Testudinis 45 grams, Ganoderma 40 grams, Herba Apocyni veneti 80 grams, 25 grams, Rhizoma Gastrodiae, the Kunlun snow chrysanthemum 80 grams, Radix Polygoni Multiflori 60 grams, the Cortex Eucommiae 80 grams, 80 grams, the Radix Rehmanniae, Fructus Lycii 80 grams, Fructus Mori 80 grams, the Radix Paeoniae Alba 40 grams, Radix Salviae Miltiorrhizae 80 grams, Fructus Crataegi 50 grams, Fructus Trichosanthis 50 grams, Spica Prunellae 60 grams, Radix Scrophulariae 40 grams, Radix Ophiopogonis 50 grams, Flos Chrysanthemi 50 grams, Radix Gentianae 25 grams, Herba Leonuri 40 grams, Herba Bidentis Bipinnatae 50 grams, Rhizoma Alismatis 25 grams, the Radix Aucklandiae 25 grams, Radix Puerariae 40 grams, Ramulus Mori 40 grams, 25 grams, Flos Carthami, Herba Menthae 40 grams, Fructus Ligustri Lucidi 50 grams, Herba Ecliptae 40 grams, Rhizoma Chuanxiong 40 grams, Radix Cyathulae 40 grams, Cortex Lycii 40 grams, 50 grams, Folium Nelumbinis, 40 grams, Flos Sophorae and Semen Cassiae 40 grams, pulverize, cross 100 mesh sieves, add in above-mentioned filtrate, stir, be evaporated to dry, pulverize, cross 80 mesh sieves, obtain.
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CN105749147A (en) * 2016-03-01 2016-07-13 徐立勇 Medicine for treating hypertension and hyperlipidemia and preparation method of medicine
CN105833055A (en) * 2016-05-17 2016-08-10 贾桥 Traditional Chinese medicine composition for treating hypertension, hyperlipidemia and hyperglycemia and preparing method and application thereof
CN105902816A (en) * 2016-05-26 2016-08-31 李旭东 Chinese medicinal composition for treating primary aldosteronism
CN105935429A (en) * 2016-07-14 2016-09-14 魏作平 Traditional Chinese medicine composition for treating coronary heart disease and hypertension
CN105998485A (en) * 2016-06-30 2016-10-12 安龙县东方五官灵制品厂 Medicine for treating hypertension and preparation method thereof
CN105998756A (en) * 2016-07-26 2016-10-12 王晨 Medicament for treating hypertension and coronary heart disease and preparation method of medicament
CN106074871A (en) * 2016-08-16 2016-11-09 余桂火 A kind of treat hypertension, hyperlipidemia, the Chinese medicine preparation of diabetes and preparation method
CN106902256A (en) * 2015-12-01 2017-06-30 卢昕冉 Pharmaceutical composition and its application
CN107549412A (en) * 2017-10-26 2018-01-09 浦北县德海种养农产品加工专业合作社 Mangrove fruit blood-pressure decreasing tea and preparation method thereof
CN107952000A (en) * 2018-01-10 2018-04-24 古天财 A kind of blood pressure lowering Chinese medicinal composition and application process

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106902256A (en) * 2015-12-01 2017-06-30 卢昕冉 Pharmaceutical composition and its application
CN105749147A (en) * 2016-03-01 2016-07-13 徐立勇 Medicine for treating hypertension and hyperlipidemia and preparation method of medicine
CN105833055A (en) * 2016-05-17 2016-08-10 贾桥 Traditional Chinese medicine composition for treating hypertension, hyperlipidemia and hyperglycemia and preparing method and application thereof
CN105902816A (en) * 2016-05-26 2016-08-31 李旭东 Chinese medicinal composition for treating primary aldosteronism
CN105998485A (en) * 2016-06-30 2016-10-12 安龙县东方五官灵制品厂 Medicine for treating hypertension and preparation method thereof
CN105935429A (en) * 2016-07-14 2016-09-14 魏作平 Traditional Chinese medicine composition for treating coronary heart disease and hypertension
CN105998756A (en) * 2016-07-26 2016-10-12 王晨 Medicament for treating hypertension and coronary heart disease and preparation method of medicament
CN106074871A (en) * 2016-08-16 2016-11-09 余桂火 A kind of treat hypertension, hyperlipidemia, the Chinese medicine preparation of diabetes and preparation method
CN107549412A (en) * 2017-10-26 2018-01-09 浦北县德海种养农产品加工专业合作社 Mangrove fruit blood-pressure decreasing tea and preparation method thereof
CN107952000A (en) * 2018-01-10 2018-04-24 古天财 A kind of blood pressure lowering Chinese medicinal composition and application process

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