CN105012184B - A kind of cosmetic composition for improving cutin skin - Google Patents
A kind of cosmetic composition for improving cutin skin Download PDFInfo
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- CN105012184B CN105012184B CN201510451387.7A CN201510451387A CN105012184B CN 105012184 B CN105012184 B CN 105012184B CN 201510451387 A CN201510451387 A CN 201510451387A CN 105012184 B CN105012184 B CN 105012184B
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- skin
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- cutin
- cosmetic composition
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- 239000000203 mixture Substances 0.000 title claims abstract description 54
- 239000002537 cosmetic Substances 0.000 title claims abstract description 36
- 229920000832 Cutin Polymers 0.000 title claims abstract description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 34
- IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 claims abstract description 23
- QBYIENPQHBMVBV-HFEGYEGKSA-N (2R)-2-hydroxy-2-phenylacetic acid Chemical compound O[C@@H](C(O)=O)c1ccccc1.O[C@@H](C(O)=O)c1ccccc1 QBYIENPQHBMVBV-HFEGYEGKSA-N 0.000 claims abstract description 22
- 229960002510 mandelic acid Drugs 0.000 claims abstract description 22
- 235000010254 Jasminum officinale Nutrition 0.000 claims abstract description 21
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims abstract description 21
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229930003537 Vitamin B3 Natural products 0.000 claims abstract description 18
- 229960003512 nicotinic acid Drugs 0.000 claims abstract description 18
- 239000011708 vitamin B3 Substances 0.000 claims abstract description 18
- 235000019160 vitamin B3 Nutrition 0.000 claims abstract description 18
- 239000008367 deionised water Substances 0.000 claims abstract description 14
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 14
- 240000005385 Jasminum sambac Species 0.000 claims abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 45
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 24
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 20
- 238000007792 addition Methods 0.000 claims description 13
- 235000011187 glycerol Nutrition 0.000 claims description 12
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 12
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 10
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 10
- 235000021355 Stearic acid Nutrition 0.000 claims description 6
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 6
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 6
- 239000008117 stearic acid Substances 0.000 claims description 6
- 239000003963 antioxidant agent Substances 0.000 claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 5
- 238000011049 filling Methods 0.000 claims description 5
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 229960001295 tocopherol Drugs 0.000 claims description 5
- 229930003799 tocopherol Natural products 0.000 claims description 5
- 235000010384 tocopherol Nutrition 0.000 claims description 5
- 239000011732 tocopherol Substances 0.000 claims description 5
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 5
- 239000006210 lotion Substances 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 239000004519 grease Substances 0.000 claims description 2
- 235000009508 confectionery Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 239000012153 distilled water Substances 0.000 abstract description 4
- 238000009472 formulation Methods 0.000 abstract description 4
- 206010020649 Hyperkeratosis Diseases 0.000 abstract description 3
- 208000001126 Keratosis Diseases 0.000 abstract description 3
- 239000000654 additive Substances 0.000 abstract description 3
- 230000000996 additive effect Effects 0.000 abstract description 3
- 230000003325 follicular Effects 0.000 abstract description 3
- 239000011159 matrix material Substances 0.000 abstract description 3
- 230000004060 metabolic process Effects 0.000 abstract description 3
- 229940088594 vitamin Drugs 0.000 abstract description 3
- 229930003231 vitamin Natural products 0.000 abstract description 3
- 235000013343 vitamin Nutrition 0.000 abstract description 3
- 239000011782 vitamin Substances 0.000 abstract description 3
- 208000024891 symptom Diseases 0.000 abstract description 2
- 150000003722 vitamin derivatives Chemical class 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 43
- 239000000686 essence Substances 0.000 description 22
- 241000207840 Jasminum Species 0.000 description 21
- 239000003921 oil Substances 0.000 description 10
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 description 8
- 239000002304 perfume Substances 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 208000002874 Acne Vulgaris Diseases 0.000 description 4
- 206010000496 acne Diseases 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 125000005456 glyceride group Chemical group 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 206010013786 Dry skin Diseases 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 3
- 210000000481 breast Anatomy 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 230000037336 dry skin Effects 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 229960003966 nicotinamide Drugs 0.000 description 3
- 235000005152 nicotinamide Nutrition 0.000 description 3
- 239000011570 nicotinamide Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 235000002906 tartaric acid Nutrition 0.000 description 3
- 239000011975 tartaric acid Substances 0.000 description 3
- 206010015150 Erythema Diseases 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010029400 Nicotinic acid deficiency Diseases 0.000 description 2
- 208000002141 Pellagra Diseases 0.000 description 2
- 241000700647 Variola virus Species 0.000 description 2
- QUKGYYKBILRGFE-UHFFFAOYSA-N benzyl acetate Chemical compound CC(=O)OCC1=CC=CC=C1 QUKGYYKBILRGFE-UHFFFAOYSA-N 0.000 description 2
- -1 compounds vitamin Chemical class 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- ICBPURKUPVLVCM-UHFFFAOYSA-N 1,5-dimethyl-2-phenylpyrazol-3-one;2-hydroxy-2-phenylacetic acid Chemical compound OC(=O)C(O)C1=CC=CC=C1.CN1C(C)=CC(=O)N1C1=CC=CC=C1 ICBPURKUPVLVCM-UHFFFAOYSA-N 0.000 description 1
- 208000021959 Abnormal metabolism Diseases 0.000 description 1
- 230000005778 DNA damage Effects 0.000 description 1
- 231100000277 DNA damage Toxicity 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 244000223014 Syzygium aromaticum Species 0.000 description 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 1
- 206010053692 Wound complication Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 229940007550 benzyl acetate Drugs 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 238000010835 comparative analysis Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 210000002500 microbody Anatomy 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 230000037312 oily skin Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 150000003892 tartrate salts Chemical class 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
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- Cosmetics (AREA)
Abstract
The present invention relates to a kind of for improving the cosmetic composition of cutin skin, and the composition is by following mass percents at being grouped as：Mandelic acid 0.1~5.8%, vitamin B3 0~10%, Jasmine extracting solution 0~5%, surplus are the matrix and deionized water or distilled water of cosmetics exterior-applied formulation.Cosmetic composition of the present invention is with mandelic acid for main activated feedstock, vitamin activity additive and natural extract are compounded, various composition reasonable combination, collocation are utilized, improve cutin skin and follicular keratosis symptom in a manner of combination and cooperation, and maintains the normal physiological metabolism of skin.
Description
Technical field
The present invention relates to a kind of cosmetic compositions, more particularly, to a kind of cosmetic combinations for improving cutin skin
Object.
Background technology
Cuticula is located at the outermost layer of skin, has the function of protecting skin, locks moisture.Modern is because contacting external ring
Border condition is deteriorated, and the factors such as diet is unbalanced, daily life system is abnormal, stay up late, smoke, drinking, mood influence, and can often make generation
It thanks to speed to slow down, abnormal metabolism makes horn cell not fall off naturally, is thickly deposited in surface, causes skin thick
Skin care products that is rough, obscure, being put on the skin, often the blocked up barrier in the roads Ye Beizhe block, can not be absorbed by following living cells.Therefore,
We will prevent cutin and thicken.Skin surface weekly all can be metabolic, and excessive old useless cutin, which is piled up on skin, to be caused
Skin is born, therefore using the old useless cutin of exfoliating removal skin surface, skin is allowed to breathe again.
Product design currently used for improving cutin skin generally mainly uses chemical exfoliating and physics exfoliating not
Same mode, chemical exfoliating generally use the larger fruit acids feedstocks of irritations such as Glycolic acid, and simple tartaric acid class is in removal cutin
While be likely to result in the generations of the situations such as skin allergy.Physics mode is generally using addition frosted particle, mineral microbody
The raw materials such as particle, high molecular polymer, soluble soft pearl particle, remove cutin using mechanical friction, can only generally remove
The cutin on most surface layer, and it is easier to cause the physical friction of skin to injure.
Invention content
In order to overcome the shortcomings of the prior art, the present invention provides one kind for conditioning skin cutin excessively and skin
The cosmetic composition of follicular keratosis.The cosmetic composition compounds vitamin activity additive using mandelic acid as primary raw material
And natural extract, using various composition reasonable combination, collocation keeps skin health, angling normal through a variety of ways.
A kind of cosmetic composition for improving cutin skin, the composition is by following mass percents at grouping
At：Mandelic acid 0.1~5.8%, vitamin B3 0~10%, Jasmine extracting solution 0~5%, surplus are the base of cosmetics exterior-applied formulation
Matter and deionized water or distilled water.
Mandelic acid also known as Alpha-hydroxy phenylacetic acid, colorless plate or granular solids.It is soluble easily in water, ethyl alcohol.Because it is especially
Benzene ring structure, be the affinity that currently the only lipophilicity tartaric acid and skin has height.Readily permeable cuticula, it is any
Skin quality is all suitable for, and is not stimulated mildly, and the side effect that general tartaric acid is brought is not likely to produce.Whelk, hair follicle cutin can effectively be solved
Extremely, skin the problems such as acne, pore is coarse.It is effective for acne, the special brilliant white of skin, any skin quality can be also felt after use
It can all implement, not stimulate mildly, be not likely to produce general tartaric acid and change the side effect such as redness of skin, burn and form a scab.It has been not easy to
The situation that sunshine is cracked down upon evil forces.For the oily skin of fuel-displaced severity, sebum can be reached really using tussol stoste
The reduced effect of secretion.In addition, if sebum secretion is reduced, the generation of acne small pox can also be reduced therewith.It is for small pox flesh
The improvement of skin and cutin skin and antibacterial effect are also very good.
Vitamin B3, also known as niacinamide, clinical medicine prove that niacinamide can promote the energetic supersession of cell, are lipid generations
It thanks, the oxidation and glycogen of tissue respiration decompose required ingredient, and ingredient shortage is the eupnea that can influence cell
With metabolism and pellagra occurs, show niacinamide have anti-inflammatory activity, the DNA damage reparation of the inductions such as ultraviolet light can be promoted, press down
UVB processed is radiated photic carcinous, and clinically early to have been widely used for pellagra, persistence swells the skin diseases such as erythema, acne.
Principle for improving cutin skin is to accelerate the metabolism of cell, promotes the synthesis of epidermal protein matter, improves the screen of skin
Hinder function, moisturizing, the comprehensive care such as anti-ageing are provided.
Jasmine extracting solution, in the whole world especially torrid areas, the jasmine with foundation for heavy florals is the most well-known flowers
One of, most of jasmine is typically evergreen or fallen leaves property plant.Jasmine and its essential oil are widely used in cosmetics and perfume row
Industry, and have the function of calmness of releiving.Main component includes benzyl acetate, benzyl alcohol, terpenes linalool, bergamio, jasmine
Jasmine ketone, clove tree atmosphere, fanesol and other compounds.Jasmine not only facilitates skin and keeps elasticity, it helps reduces
Inflammation and alleviation wound pain.Keep the stimulated skin of inflammation smooth, moisturizing simultaneously regulates and controls fat secretion.
Preferably, the composition by following mass percents at being grouped as：Mandelic acid 1.0~5.5%, vitamin
B3 0.1~5.0%, Jasmine extracting solution 0.1~1.0%, surplus are the matrix and deionized water of cosmetics exterior-applied formulation or steaming
Distilled water.
Preferably, the cosmetic composition can be one of following forms：Essence, lotion, cream, frost, gel.This
Invention assists vitamin B3 and Jasmine extracting solution, and add the matrix of cosmetics exterior-applied formulation using mandelic acid as main component
（Such as emulsifier, grease, emollient, moisturizer, preservative, essence, thickener）And deionized water or distilled water and be made not
With the cosmetics of form.
Preferably, the composition by following mass percents at being grouped as：Mandelic acid 4%, vitamin B3 2%, jasmine
Jasmine extracting solution 0.5%, glycerine 5%, butanediol 5%, methyl hydroxybenzoate 0.1%, essence 0.1%, sodium hydroxide 0.5%, surplus are to go
Ionized water.
Preferably, the composition by oil phase, water phase, addition phase composition,
The oil phase is by following mass percents at being grouped as：Stearic alcohol ether -21 2%, stearic alcohol ether -2 1%, tristearin
Acid glyceride 2%, Parleam 5%, tocopherol 0.1%, stearic acid 1%, isopropyl palmitate 8%, BHT antioxidants
0.05%；
The addition is mutually by following mass percents at being grouped as：Jasmine extracting solution 0.5%, sodium hydroxide 0.5%, perfume
Essence 0.1%, methyl hydroxybenzoate 0.1%；
The water phase is by following mass percents at being grouped as：Mandelic acid 4%, vitamin B3 2%, glycerine 5%, butanediol
5%, surplus is deionized water.
Preferably, the composition is prepared by following step：
（1）Deionized water and glycerine, butanediol, methyl hydroxybenzoate mixing, are heated to 80 DEG C, stir to dissolve；
（2）Solution is cooled to 40 DEG C, mandelic acid, vitamin B3, Jasmine extracting solution and essence is added, keeps its mixing equal
It is even；
（3）PH to 3.5~4.0 is adjusted with sodium hydroxide；
（4）This Essence is tested, after qualified, then carries out filling can be obtained product.
Preferably, the composition is prepared by following step：
（1）After oil phase, water phase are heated separately to 80 DEG C, two-phase mixtures homogeneous 5 minutes, stirring cooling cools to 45 DEG C
Addition phase is added；
（2）PH to 3.5~4.0 is adjusted with sodium hydroxide；
（3）This lotion is tested, after qualified, then carries out filling can be obtained product.
Cosmetic composition of the present invention, for main activated feedstock, is compounded vitamin activity additive and naturally carried with mandelic acid
Object is taken, using various composition reasonable combination, collocation improves cutin skin and follicular keratosis symptom in a manner of combination and cooperation,
And maintain the normal physiological metabolism of skin.
Specific implementation mode
The present invention is further explained in the light of specific embodiments, but the scope of the present invention is not limited to this.
Mandelic acid that the present invention uses, vitamin B3, Jasmine extracting solution derive from commercially available.
Embodiment 1
Cutin Essence
A kind of cosmetic composition for improving cutin skin, the composition is by following mass percents at grouping
At：Mandelic acid 4%, vitamin B3 2%, Jasmine extracting solution 0.5%, glycerine 5%, butanediol 5%, methyl hydroxybenzoate 0.1%, essence
0.1%, sodium hydroxide 0.5%, surplus are deionized water.
It is prepared by following step：
（1）Deionized water and glycerine, butanediol, methyl hydroxybenzoate mixing, are heated to 80 DEG C, stir to dissolve；
（2）Solution is cooled to 40 DEG C, mandelic acid, vitamin B3, Jasmine extracting solution and essence is added, keeps its mixing equal
It is even；
（3）PH to 3.5~4.0 is adjusted with sodium hydroxide；
（4）This Essence is tested, after qualified, then carries out filling can be obtained product.
Embodiment 2
Cutin essence breast
It is a kind of for improving the cosmetic composition of cutin skin, the composition by oil phase, water phase, addition phase composition,
The oil phase is by following mass percents at being grouped as：Stearic alcohol ether -21 2%, stearic alcohol ether -2 1%, tristearin
Acid glyceride 2%, Parleam 5%, tocopherol 0.1%, stearic acid 1%, isopropyl palmitate 8%, BHT antioxidants
0.05%；
The addition is mutually by following mass percents at being grouped as：Jasmine extracting solution 0.5%, sodium hydroxide 0.5%, perfume
Essence 0.1%, methyl hydroxybenzoate 0.1%；
The water phase is by following mass percents at being grouped as：Mandelic acid 4%, vitamin B3 2%, glycerine 5%, butanediol
5%, surplus is deionized water.
It is prepared by following step：
（1）After oil phase, water phase are heated separately to 80 DEG C, two-phase mixtures homogeneous 5 minutes, stirring cooling cools to 45 DEG C
Addition phase is added；
（2）PH to 3.5~4.0 is adjusted with sodium hydroxide；
（3）This lotion is tested, after qualified, then carries out filling can be obtained product.
Embodiment 3
A kind of cosmetic composition for improving cutin skin, the composition is by following mass percents at grouping
At：Mandelic acid 4.5%, vitamin B3 4.5%, Jasmine extracting solution 1.0%, glycerine 3%, butanediol 7%, methyl hydroxybenzoate 0.1%,
Essence 0.1%, sodium hydroxide 0.7%, surplus are deionized water.
The cosmetic composition is Essence, and preparation method is with reference to embodiment 1.
Embodiment 4
A kind of cosmetic composition for improving cutin skin, the composition is by following mass percents at grouping
At：Mandelic acid 5.5%, glycerine 5%, butanediol 5%, methyl hydroxybenzoate 0.1%, essence 0.1%, sodium hydroxide 0.8%, surplus be go from
Sub- water.
The cosmetic composition is Essence, and preparation method is with reference to embodiment 1.
Embodiment 5
A kind of cosmetic composition for improving cutin skin, the composition is by following mass percents at grouping
At：Mandelic acid 3.5%, vitamin B3 6%, Jasmine extracting solution 2.0%, glycerine 8%, butanediol 6%, methyl hydroxybenzoate 0.1%, perfume
Essence 0.1%, sodium hydroxide 0.5%, surplus is deionized water.
The cosmetic composition is Essence, and preparation method is with reference to embodiment 1.
Embodiment 6
It is a kind of for improving the cosmetic composition of cutin skin, the composition by oil phase, water phase, addition phase composition,
The oil phase is by following mass percents at being grouped as：Stearic alcohol ether -21 2%, stearic alcohol ether -2 1%, tristearin
Acid glyceride 2%, Parleam 5%, tocopherol 0.1%, stearic acid 1%, isopropyl palmitate 8%, BHT antioxidants
0.05%；
The addition is mutually by following mass percents at being grouped as：Jasmine extracting solution 0.8%, sodium hydroxide 0.5%, perfume
Essence 0.1%, methyl hydroxybenzoate 0.1%；
The water phase is by following mass percents at being grouped as：Mandelic acid 2.5%, vitamin B3 3%, glycerine 5%, fourth two
Alcohol 5%, surplus are deionized water.
The cosmetic composition is essence breast, and preparation method is with reference to embodiment 2.
Embodiment 7
It is a kind of for improving the cosmetic composition of cutin skin, the composition by oil phase, water phase, addition phase composition,
The oil phase is by following mass percents at being grouped as：Stearic alcohol ether -21 2%, stearic alcohol ether -2 1%, tristearin
Acid glyceride 2%, Parleam 5%, tocopherol 0.1%, stearic acid 1%, isopropyl palmitate 8%, BHT antioxidants
0.05%；
The addition is mutually by following mass percents at being grouped as：Jasmine extracting solution 0.3%, sodium hydroxide 0.5%, perfume
Essence 0.1%, methyl hydroxybenzoate 0.1%；
The water phase is by following mass percents at being grouped as：Mandelic acid 1.0%, vitamin B3 0.8%, glycerine 5%, fourth
Glycol 5%, surplus are deionized water.
The cosmetic composition is essence breast, and preparation method is with reference to embodiment 2.
Embodiment 8
Cosmetics made from above-described embodiment 1~7 and a certain commercially available exfoliating cosmetics（As a control group）, respectively
Through 100 serious subjects of 20~50 years old keratinization continuously 28 days on probation, the various embodiments described above and right were evaluated in comparative analysis
According to the nursing efficacy of group.Wherein, the nursing efficacy is skin cleaning, cutin softening, cutin are dispelled, had dry skin, skin
Coarse equal improvement situation, the results are shown in Table 1.
Table 1
The cosmetic composition of above-described embodiment 1~7 does not find irritation, allergic phenomena and without skin during on probation
Skin damage phenomenon, a certain commercially available exfoliating cosmetics show moderate irritation during on probation, and skin injury is serious, with pain
Sense.
As known from Table 1：Cosmetics made from Examples 1 to 7 and a certain commercially available exfoliating cosmetics are to skin cleaning, angle
Matter softening, cutin is dispelled, is had dry skin, pachylosis has a degree of improvement, and Examples 1 to 7 is to skin cleaning, cutin
Softening, cutin are dispelled, are had dry skin, the improvement degree of pachylosis etc. is obviously higher than the improvement degree of control group；And it combines
In object when mandelic acid 4%, vitamin B3 2%, Jasmine extracting solution 0.5%, every effect of product is best.
Claims (1)
1. a kind of cosmetic composition for improving cutin skin, it is characterised in that：The composition by oil phase, water phase, add
Add phase composition,
The oil phase is by following mass percents at being grouped as：Stearic alcohol ether -21 2%, stearic alcohol ether -2 1%, stearic acid are sweet
Grease 2%, Parleam 5%, tocopherol 0.1%, stearic acid 1%, isopropyl palmitate 8%, BHT antioxidants 0.05%；
The addition is mutually by following mass percents at being grouped as：Jasmine extracting solution 0.5%, sodium hydroxide 0.5%, essence
0.1%, methyl hydroxybenzoate 0.1%；
The water phase is by following mass percents at being grouped as：Mandelic acid 4%, vitamin B3 2%, glycerine 5%, butanediol 5%,
Surplus is deionized water；
It is prepared by following step：
（1）After oil phase, water phase are heated separately to 80 DEG C, two-phase mixtures homogeneous 5 minutes, stirring cooling cools to 45 DEG C of additions
Add phase；
（2）PH to 3.5~4.0 is adjusted with sodium hydroxide；
（3）This lotion is tested, after qualified, then carries out filling can be obtained product.
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| CN112370415B (en) * | 2020-11-24 | 2022-04-22 | 杭州百芮生物科技有限公司 | Quick-acting pore-shrinking composition and preparation method thereof |
| CN112791009A (en) * | 2021-03-19 | 2021-05-14 | 山东利蒙药业有限公司 | Jasmine nicotinamide frosted film and production process thereof |
| CN113332160A (en) * | 2021-07-22 | 2021-09-03 | 杭州彼心生物科技有限公司 | Cosmetic composition for conditioning peritrichotic skin |
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| CN102068389A (en) * | 2010-09-06 | 2011-05-25 | 厦门澳丽尔日化有限公司 | Micro-emulsified environmentally-friendly facial treatment milk and preparation method thereof |
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| CN104398435A (en) * | 2014-12-01 | 2015-03-11 | 唯美度科技（北京）有限公司 | Mild cutin removing mask and preparation method thereof |
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| CN103767967A (en) * | 2014-01-08 | 2014-05-07 | 肇庆迪彩日化科技有限公司 | Hair-caring composition containing lotus leaf/pogostemon cablin composite essential oil micro-capsule emulsion and preparation method of composition |
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