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CN104856036B - Health care medicated diet for treating iron-deficiency anemia and preparation method of health care medicated diet - Google Patents

Health care medicated diet for treating iron-deficiency anemia and preparation method of health care medicated diet Download PDF

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CN104856036B
CN104856036B CN201510299906.2A CN201510299906A CN104856036B CN 104856036 B CN104856036 B CN 104856036B CN 201510299906 A CN201510299906 A CN 201510299906A CN 104856036 B CN104856036 B CN 104856036B
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health care
medicated diet
herba
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CN104856036A (en
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侯开娟
牟海霞
刘剑英
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Hou Kaijuan
Liu Jianying
Mou Haixia
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a health care medicated diet for treating iron-deficiency anemia and a preparation method of health care medicated diet. The health care medicated diet is prepared from the following medicinal raw materials in parts by weight: 12-18 parts of Chinese yam, 8-14 parts of shiny cinquefoil herb, 9-13 parts of donkey-hide glue, 10-14 parts of thickrostrate begonia herb, 6-10 parts of common scouring rush herb, 8-11 parts of root of delavay morina, 10-15 parts of mulberry fruit, 9-16 parts of root and leaves of evergreen mucuna, 13-17 parts of ginseng, 9-15 parts of root-bark of Chinese wolfberry, 20-30 parts of pork liver, 15-20 parts of Chinese date and 16-24 parts of spinach. According to the invention, the health care medicated diet comprises a plurality of raw materials, is prepared according to a traditional production method, and retains properties of the medicinal raw materials; the medicinal raw materials coordinates and cooperates with one another; the health care medicated diet has effects of invigorating qi and blood, nourishing yin and promoting the production of body fluid, and tonifying the spleen and stomach, is safe, effective, free of toxic or side effects and suitable for patients with anemia to take for long term.

Description

The health care medicated diet for the treatment of iron deficiency anemia and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, more particularly to a kind of health care medicated diet treating iron deficiency anemia and preparation method.
Background technology
Ferrum is one of necessary trace element of human body, is cytochrome system important component part, be body hemoglobin, Haemachrome enzyme, Myoglobin important component part, its wide participation body physiological function and biochemical reaction.Iron deficiency anemia (Iron-Deficiency Anemia, IDA)Refer to generate because internal storage ferrum is depleted, can not meet normocyte Needs and the anemia that occurs.Before the generation of erythrocyte is restricted, internal iron promoter exhausts, now referred to as lacks Ferrum.The feature of iron deficiency anemia is to lack in bone marrow and its hetero-organization to contaminate ferrum, and serum ferritin and Transferrin turation are equal Reduce, assume microcytic hypochromic anemia.Be internal ferrum storage can not meet normocyte generation needs and occur Anemia.Worldwide incidence rate is very high for iron deficiency anemia, especially prominent in developing country.Severely impact patient's Physical ability, work efficiency, and the muscle power of child and intelligent development, are China and that other developing countries are faced is mainly public Hygienic issues.
The traditional Chinese medical science thinks that primary disease disease position focuses on taste, and diet water paddy turns to cereal nutrient under the transportation capabilities of spleen, and middle Jiao is subject to Gas extracting juice, change red for blood.Taste, with burnt between two parties, belong to middle soil together, The spleen has the function to transport and transform nutrients, stomach receiving food and drink, and dirty the receiving of taste two coordinates, lifting Phase factor, dryness and dampness coordinating each other, complement each other, just can complete diet digestive, absorb defeated cloth cereal nutrient, finalization anger blood.Primary disease should Dispel the cause of disease first, in treatment based on qi-restoratives, strengthening the spleen and nourishing the stomach, it is main method for the treatment of that QI invigorating rises blood.Wu Hanxiang is with Fructus Jujubae vitriol ball for place Side, is ball treatment iron deficiency anemia with Alumen, Pulvis Aci, Rhizoma dioscoreae, Fructus Jujubae, clinically obtains good effect.
Authorization Notice No. CN103055085A(Application number 201310050450.7)Chinese invention patent document disclose A kind of Chinese medicine preparation treating iron deficiency anemia, is made up of the crude drug of following weight portion:Radix Astragali 18-22 part, Radix Pseudostellariae 8-10 Part, Herba Agrimoniae 13-17 part, Radix Rehmanniae Preparata 10-14 part, Radix Angelicae Sinensis 13-17 part, Fructus Jujubae 18-22 part, Semen Sesami Nigrum 18-22 part, Radix Polygoni Multiflori 13-17 part, Radix Codonopsis 18-22 part, Colla Corii Asini 10-14 part, Pericarpium Citri Reticulatae 8-10 part, Rhizoma Cyperi 8-10 part, Fructus Lycii 6-8 part, Radix Glycyrrhizae 6-8 part. Application publication number CN104398721A(Application number 201410644710.8)Chinese invention patent document disclose a kind for the treatment of The combined traditional Chinese medicine of iron deficiency anemia, is made up of the crude drug of following weight portion:15 parts of Radix Codonopsis, 12 parts of the Rhizoma Atractylodis Macrocephalae, 10 parts of Poria, Radix Angelicae Sinensis 15 parts, 12 parts of Radix Rehmanniae Preparata, 12 parts of Fructus Jujubae, 10 parts of Fructus Psoraleae, 10 parts of Colla cornus cervi, 10 parts of Semen Cuscutae, 20 parts of Semen Torreyae, 10 parts of Semen Arecae, 10 parts of Caulis Sargentodoxae, 8 parts of Cortex Mori, 6 parts of Radix Glycyrrhizae.Application publication number CN104127621A(Application number 201410365724.6)China Patent of invention document discloses a kind of Chinese medicine treating iron deficiency anemia, is made up of the raw material of following weight proportioning:Radix Ginseng 10- 20th, Radix Angelicae Sinensis 10-20, Caulis Spatholobi 20-30, Fructus Lycii 8-15, Arillus Longan 5-12, Radix Astragali 10-20, Colla cornus cervi 20-30, Colla Plastri Testudiniss 10-20, Radix Polygoni Multiflori Preparata 30-40, Placenta Hominiss 10-20, Radix Glycyrrhizae Preparata 6-10, Melanteritum 8-16, Rhizoma Atractylodis Macrocephalae 10-20, Pericarpium Citri Reticulatae 5-10, Cortex Magnoliae Officinalis 10- 20th, Semen Arecae 10-20.
The western medical treatment means of iron deficiency anemia be dispel the cause of disease and supplement chalybeate, but Oral Iron Preparations common to gastrointestinal tract pair Reaction, causes scorching hot sense, nausea, epigastric discomfort, diarrhoea etc..Some patients are using injection iron in treatment, but toxic reaction Larger, some patients may produce fatefulue anaphylaxiss, not only uneconomical but also inconvenient.Therefore explore safer and more effective in The scheme of medical treatment IDA, improves the quality of life of patient, has important practical significance.
Content of the invention
For the deficiencies in the prior art, it is an object of the invention to provide prepared by one kind simply, safely and effectively treat iron deficiency The health care medicated diet of property anemia.Health care medicated diet of the present invention is suitable to Anemic patients' long-term taking.
The technical scheme is that:
The health care medicated diet for the treatment of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion:Rhizoma Dioscoreae 12-18;Pipe Secondary 8-14;Colla Corii Asini 9-13;Herba Begoniae Crassirostriss 10-14;Herba Equiseties Hiemalis 6-10;Radix Morinae Bulleyanae 8-11;Fructus Mori 10-15;Radix Seu Caulis Mucunae Sempervirentis 9-16;Radix Ginseng 13- 17;Cortex Lycii 9-15;Hepar Sus domestica 20-30;Southern Fructus Jujubae 15-20;Herba Spinaciae 16-24.
Preferably in scheme, Rhizoma Dioscoreae 14-16;Herba potentillae fulgentis 10-12;Colla Corii Asini 10-12;Herba Begoniae Crassirostriss 11-13;Herba Equiseties Hiemalis 7-9;Radix Morinae Bulleyanae 9-10;Fructus Mori 11-14;Radix Seu Caulis Mucunae Sempervirentis 11-14;Radix Ginseng 14-16;Cortex Lycii 11-13;Hepar Sus domestica 22-28;Southern Fructus Jujubae 16-19;Herba Spinaciae 18- 22.
More preferred, Rhizoma Dioscoreae 15.5;Herba potentillae fulgentis 11;Colla Corii Asini 11;Herba Begoniae Crassirostriss 12;Herba Equiseties Hiemalis 8;Radix Morinae Bulleyanae 9.5;Fructus Mori 12.5; Radix Seu Caulis Mucunae Sempervirentis 12.5;Radix Ginseng 15;Cortex Lycii 12;Hepar Sus domestica 25;Southern Fructus Jujubae 17.5;Herba Spinaciae 20.
The preparation method of the health care medicated diet for the treatment of iron deficiency anemia, step is as follows:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with ethanol as solvent, does not have more than powder 6cm, standing, makes solvent fully run through crude drug Powder, opens valve, carries out percolation with the speed of 3-6mL/min(Preferably percolation is carried out with the speed of 4-5mL/min), to be collected The amount of percolate is 12-16 times of raw material medicated powder amount(The amount of the preferably percolate of collection is 13-15 times of raw material medicated powder amount)When, Stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, be spray-dried the powder that gets dry extract, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng, Fructus Mori and southern Fructus Jujubae and step(2)Raw material after process is placed in marmite, adds clear water, and intense fire heats Boil, turn small fire and stew slowly, during stewing, every 15 minutes, stirring once, obtains medicine soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 10-20 Minute, stop working, add a cover vexed 5-10 minute(Preferably add a cover vexed 8 minutes), it is seasoned according to personal like.
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(1)In added ethanol Mass concentration be 50%-80%(The mass concentration of preferably added ethanol is 60%-70%, the matter of more preferred added ethanol Amount concentration is 65%).
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(1)Middle standing when Between be 26-52 minute(The time of preferably standing is 30-48 minute, and the time of more preferred standing is 39 minutes).
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(3)The amount of middle clear water For material quantity 6-10 times(The amount of preferably clear water is 7-9 times of material quantity, and the amount of more preferred clear water is the 8 of material quantity Times).
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(3)Middle intense fire heating Boil 8-16 minute(Preferably intense fire heated and boiled 10-14 minute, more preferred intense fire heated and boiled 12 minutes).
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(3)Middle small fire is stewed slowly 50-90 minute(Preferably small fire stewes 60-80 minute slowly, and more preferred small fire is stewed 70 minutes slowly).
The preparation method of the health care medicated diet of above-mentioned treatment iron deficiency anemia, preferred scheme is, step(4)Middle small fire decocts 13-17 minute(Preferably small fire decocts 15 minutes).
Scientific formula of the present invention, preparation method is simple.In addition, the excellent results of the present invention are also manifested by:
1、The present invention is made up of plurality of raw materials, using traditional manufacture method, remains the property of medicine of medicine, phase between each medicine Mutually coordinate, coordinate, there is vigorate qi and replenish the blood, Yin-nourishing and body fluid promoting, effect of spleen reinforcing stomach function regulating;
2、The product safety of the present invention effectively and has no toxic side effect, and is suitable to Anemic patients' long-term taking;
3、Medicine source is easy to get, and medical material is with low cost, can mitigate patient burden.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
Rhizoma Dioscoreae:Base:This product is the dry rhizome of Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor:Sweet, put down.Return through:Returns spleen, lung, kidney Warp.Effect:Spleen reinforcing nourishing the stomach, engender liquid and benefic lung, the kidney invigorating arresting seminal emission.Cure mainly:For spleen eating less, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, and kidney deficiency is lost Essence, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, loose stool of having loose bowels, leukorrhagia.
Herba potentillae fulgentis:Base:Root for rosaceous plant Herba potentillae fulgentis or whole herb with root.Nature and flavor:Cold;Pained.Return through:Spleen; Large intestine channel.Indication:Heat-clearing and toxic substances removing, relieving diarrhea with astringents, cooling blood for hemostasis.Main red white dysentery;Enteritis, diarrhea;Discharging fresh blood stool;Pulmonary tuberculosis Spitting of blood;Spit blood;Bleeding not during menses;Traumatic hemorrhage;Furuncle;Scald burn.
Colla Corii Asini:Base:For the blob of viscose boiling after the skin unhairing of equine speciess donkey.Chemical analysis:How by collagen and its Partial hydrolysate is become, nitrogenous 16.43-16.54%, substantially protein.Hydrolysis produces several amino acids, wherein depends on Propylhomoserin 10%, arginine 7%, histidine 2% etc..In terms of the aminoacid producing, Colla Corii Asini is similar to gelatin, but the former lysine More, and contain cystine, and lack tryptophan.0.75-1.09% containing ash, calcium 0.079-0.118%.Nature and flavor:Sweet, put down.Return Warp:Enter lung, liver and kidney channel.Indication:Nourishing YIN and supplementing blood, antiabortive.Control blood deficiency, cough due to consumptive disease, spit blood, epistaxis, have blood in stool, woman month Through uncomfortable, metrorrhagia, vaginal bleeding during pregnancy.
Herba Begoniae Crassirostriss(Root):Base:Root for Begoniaceae plant thick beak Flos Begoniae Evansianae.Nature and flavor:Sour in the mouth;Puckery;Cool in nature.Function Cure mainly:Removing pathogenic heat from blood and toxic substance from the body;Reducing swelling and alleviating pain.Main acute pharyngolaryngitises, gingival swelling and pain, sore furuncle poison, calentura is had blood in stool, scrofula, scabies, poisonous snake Bite, burn and scald.
Herba Equiseties Hiemalis:Base:Herb for Equisetaceae plant Herba Equiseties Hiemalis.Pharmacological action:Silicate contained by Herba Equiseties Hiemalis and tannin have receipts Hold back effect, hence for contact site, have antiinflammatory, anastalsis.1. pair cardiovascular effect:Herba Equiseti Hiemalises' alcohol extraction liquid energy increases in vitro Guinea pig heart coronary flow.0.2ml/kg(100% extracting solution)The T ripple that intravenous injection causes to pituitrin raises and heart rate Slow down and have certain antagonism and cushioning effect.2. other effects:Ferulic acid have suppression platelet aggregation and release act on dynamic There are calmness, anticonvulsant action in thing experiment.Nature and flavor:Sweetness and bitterness;Flat;Nontoxic.Return through:Lung;Liver;Gallbladder meridian.Indication:Dispelling wind is clear Heat;Cooling blood for hemostasis;Improving acuity of vision and removing nebula.The hot conjunctival congestion of main air;Mesh gives birth to nebula;Epiphora induced by wind;Discharging fresh blood stool;Hemorrhoidal bleeding;Dysentery;Married woman's moon water Constantly;Proctoptosis.
Radix Morinae Bulleyanae:Base:Root for Dipsacaceae plant spire Siberian cocklebur grass.Nature and flavor:《Yunnan Chinese herbal medicine》:" sweet slight bitter, temperature.” Indication:Control neurasthenia, cough, injury and bone fracture, leucorrhea, sexual impotence.①《Yunnan Chinese herbal medicine choosing》:" stomach reinforcing, calm, the kidney invigorating, Tonifying YANG.Control neurasthenia, dyspepsia, uterine prolapse, leukorrhagia, sexual impotence.”②《Yunnan Chinese herbal medicine》:" fill blood, connect muscle Bone.Control neurosiss, anemia, cough due to deficiency of the lung, traumatic injury, fracture.”
Fructus Mori:Base:Fruit ear for moraceae plants mulberry.Chemical analysis:Sugary, malic acid, malic acid and vitamin B1, B2, C And carotene.The fatty acid of Fructus Mori oil is mainly made up of the stearic acid of linoleic acid and amount, Oleic acid etc..Nature and flavor:Sweet, tremble with fear.Return through: Enter liver and kidney channel.Indication:Tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow liquid.Control hepatic and renal YIN deficiency, quench one's thirst, constipation, mesh is dark, tinnitus, scrofula, closes Section is unfavorable.
Radix Seu Caulis Mucunae Sempervirentis:Base:Root for the evergreen mucuna of leguminous plant and stem and leaf.Chemical analysis:Leaf contain 8-C-a-L- I Primary glycosyl luteolin, 6,8- bis--C-a-L- aralino apigenins and isorientin.The flower glucose of -3- containing delphinidin Glycoside, petunidin and malvidin.Nature and flavor:Bitter;Slight bitter;Warm in nature.Return through:Liver;Stomach.Indication:Promoting blood flow to regulate menstruation;Enrich blood easypro Muscle.Master has through uncomfortable;Dysmenorrhea;Amenorrhea;Puerperal blood deficiency;Anemia;Rheumatic arthralgia;Numb limbs and tense tendons;Traumatic injury.
Radix Ginseng:Base:Root for Araliaceae Radix Ginseng.Nature and flavor:Sweet slight bitter, temperature.Return through:Enter spleen, lung meridian.Function master Control:Strongly invigorating primordial QI, Gu de- promote the production of body fluid, calms the nerves.Control impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, lingering diarrhea of defecating, and empty cough with asthma promotees, from Antiperspirant sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's intermittent infantile convulsion, and prolonged deficiency is not multiple, all gas The card of blood deficiency of body fluid.
Cortex Lycii:Base:Root bark for eggplant kind plant Fructus Lycii etc..Chemical analysis:Root bark contains cinnamic acid and volume phenolic material Matter, glycine betaine.Also have been reported that, glycine betaine, containing only in the leaf of Fructus Lycii and fruit, is not present in root bark.Suppression thiamine is still contained in root The material of activity, this inhibitory action can be released by cysteine and vitamin C.Cupreol, Asia is still separated to obtain in Cortex Lycii Oleic acid, linolenic acid, 1 acid etc..Character:Dry root skin is short and small tubular or channel-shaped roll film, not of uniform size, typically grows 3~10 Centimetre, wide 0.6~1.5 centimetre, about 3 millimeters of thickness.Outer surface lark or brown color, coarse, there is mixed longitudinal crack, easy-peel Fall.Inner surface yellow-white, flatter, there is thin longitudinal grin.Pharmacological action:1. the effect to cardiovascular system, 2. hypoglycemic activity, 3. Refrigeration function.Nature and flavor:Sweet, tremble with fear.Return through:Enter lung, liver and kidney channel.Indication:Heat clearing away, removing heat from blood.Control asthenia hectic fever night sweat, lung-heat Cough with asthma, spits blood, epistaxis, and stranguria with blood is quenched one's thirst, hypertension, carbuncle, malignant boil.
Hepar Sus domestica:Base:Liver for porcine animals pig.Nature and flavor:Sweetness and bitterness, temperature.Return through:《Detailed outline》:" enter liver." indication: Tonifying liver, blood-nourishing, improving eyesight.Control blood deficiency and yellow complexion, nyctalopia, conjunctival congestion, edema, tinea pedis.
Fructus Jujubae:Base:Mature fruit for Rhamnaceae plant Fructus Jujubae.Chemical analysis:Saponin I containing Fructus Jujubae, II, III I, II, Ⅲ), jujuboside B, stepharine, glucose, Fructose, sucrose, adenosine cyclophosphate, ring phosphorus crow glycosides etc..Nature and flavor:Sweet, temperature.Return Warp:Enter spleen, stomach.Indication:Spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, adjust battalion to defend, solve poison of drug.Control insufficiency of stomach lack of appetite, the weak loose stool of spleen, gas Blood deficiency of body fluid, disharmony of nutrient QI with defensive QI, severe palpitation.Married woman's stolen goods are hot-tempered.Southern Fructus Jujubae:The Fructus Jujubae that is produced from Zhejiang processes big gun through series of process step System forms.
Herba Spinaciae:Base:Whole herb with root for chenopod Herba Spinaciae.Nature and flavor:Sweet;Mild-natured.Return through:Liver;Stomach;Large intestine;Small intestinal Warp.Indication:Blood-nourishing;Hemostasis;Suppressing the hyperactive liver;Moisturize.Main epistaxis;Have blood in stool;Headache;Dizzy;Conjunctival congestion;Nyctalopia;Quench one's thirst taking fluids profusely;Just Close;Hemorrhoid.
Specific embodiment
Describe technical scheme with reference to embodiment and experimental example in detail, but protection domain not limited to this.
Embodiment 1 treats the health care medicated diet of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion (45g/ part):12 parts of Rhizoma Dioscoreae;8 parts of Herba potentillae fulgentis;9 parts of Colla Corii Asini;10 parts of Herba Begoniae Crassirostriss;6 parts of Herba Equiseties Hiemalis;8 parts of Radix Morinae Bulleyanae;10 parts of Fructus Mori;The oxen and horses 9 parts of rattan;13 parts of Radix Ginseng;9 parts of Cortex Lycii;20 parts of Hepar Sus domestica;15 parts of southern Fructus Jujubae;16 parts of Herba Spinaciae.
Treat the health care medicated diet of iron deficiency anemia, preparation method is:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with mass concentration be 50% ethanol as solvent, do not had more than a powder 6cm, stood 26 minutes, Make solvent fully run through raw material medicated powder, open valve, percolation is carried out with the speed of 3mL/min, the amount of percolate to be collected is When 12 times of raw material medicated powder amount, stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, and spray drying gets dry extract Powder, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng, Fructus Mori and southern Fructus Jujubae and step(2)Raw material after process is placed in marmite, adds the clear of 6 times of material quantities Water, intense fire heated and boiled 8 minutes, turn small fire and stew 50 minutes slowly, during stewing, every 15 minutes, stirring once, obtains medicine Soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 10 points Clock, stops working, adds a cover vexed 5 minutes, be seasoned according to personal like.
The eating method of gained health care medicated diet of the present invention is:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add Subtract), it is within two weeks a course for the treatment of.
Typical case:Old XX, man, 17 years old, patient was to our hospital in September in 2010 11 days.No substantially lured before one month Because fatigue and weak, having palpitation, household sees his pale complexion, but does not arrive examination in hospital and treatment.Before one week, patient is at school When suddenly dizziness occurs, powerless, symptoms of emesis, our hospital is delivered to by classmate and teacher and goes to a doctor.Check:Patient is conscious, weak, Pale complexion, blood routine examination:WBC 4.5×109/ L, erythrocyte(RBC) 2.8×1012/ L, Hb 61g/L, Plt 359 × 109/ L, mean corpuscular volume (MCV)(MCV)73.2fL, mean corpuscular hemoglobin(MCH)21.8pg, mean corpuscular is blood red Protein concentration(MCHC)298g/L, reticulocyte 2.0%.Stool blood is negative.Serum levels of iron and ferritin are less than normal, diagnosis For iron deficiency anemia.
Take the health care medicated diet that the present embodiment gained treats iron deficiency anemia, instructions of taking:The daily morning and evening is each once, every time 150-200mL(Take the circumstances into consideration to add and subtract), it is within two weeks a course for the treatment of.After taking two courses for the treatment of, the symptom such as patient is weak, dizzy disappears, face Color is ruddy, and routine blood test is obviously improved, and continues to take three courses for the treatment of, and patient's routine blood test is normal, and no Anemia is it is proposed that patient is long-term Take, better.
Embodiment 2 treats the health care medicated diet of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion (25g/ part):18 parts of Rhizoma Dioscoreae;14 parts of Herba potentillae fulgentis;13 parts of Colla Corii Asini;14 parts of Herba Begoniae Crassirostriss;10 parts of Herba Equiseties Hiemalis;11 parts of Radix Morinae Bulleyanae;15 parts of Fructus Mori; 16 parts of Radix Seu Caulis Mucunae Sempervirentis;17 parts of Radix Ginseng;15 parts of Cortex Lycii;30 parts of Hepar Sus domestica;20 parts of southern Fructus Jujubae;24 parts of Herba Spinaciae.
The preparation method of the health care medicated diet for the treatment of iron deficiency anemia, step is as follows:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with mass concentration be 80% ethanol as solvent, do not had more than a powder 6cm, stood 52 minutes, Make solvent fully run through raw material medicated powder, open valve, percolation is carried out with the speed of 6mL/min, the amount of percolate to be collected is When 16 times of raw material medicated powder amount, stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, and spray drying gets dry extract Powder, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng and Fructus Mori and step(2)Raw material after process is placed in marmite, adds the clear water of 10 times of material quantities, Intense fire heated and boiled 16 minutes, turns small fire and stewes 90 minutes slowly, and during stewing, every 15 minutes, stirring once, obtains medicine Soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 20 points Clock, stops working, adds a cover vexed 10 minutes, be seasoned according to personal like.
The eating method of gained health care medicated diet of the present invention is:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add Subtract), it is within two weeks a course for the treatment of.
Embodiment 3 treats the health care medicated diet of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion (40g/ part):14 parts of Rhizoma Dioscoreae;10 parts of Herba potentillae fulgentis;10 parts of Colla Corii Asini;11 parts of Herba Begoniae Crassirostriss;7 parts of Herba Equiseties Hiemalis;9 parts of Radix Morinae Bulleyanae;11 parts of Fructus Mori;Cattle 11 parts of horse rattan;14 parts of Radix Ginseng;11 parts of Cortex Lycii;22 parts of Hepar Sus domestica;16 parts of southern Fructus Jujubae;18 parts of Herba Spinaciae.
The preparation method of the health care medicated diet for the treatment of iron deficiency anemia, step is as follows:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with mass concentration be 60% ethanol as solvent, do not had more than a powder 6cm, stood 30 minutes, Make solvent fully run through raw material medicated powder, open valve, percolation is carried out with the speed of 4mL/min, the amount of percolate to be collected is When 13 times of raw material medicated powder amount, stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, and spray drying gets dry extract Powder, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng and Fructus Mori and step(2)Raw material after process is placed in marmite, adds the clear water of 7 times of material quantities, military Fiery heated and boiled 10 minutes, turns small fire and stewes 60 minutes slowly, and during stewing, every 15 minutes, stirring once, obtains medicine soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 13 points Clock, stops working, adds a cover vexed 6 minutes, be seasoned according to personal like.
The eating method of gained health care medicated diet of the present invention is:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add Subtract), it is within two weeks a course for the treatment of.
Typical case:
Grandson XX, female, 9 years old, infant cause cough, 38.6 DEG C of heating in one month, to certain hospital admission local.It has been diagnosed to be lean Mass formed by blood stasis shape, gives hematonic treatment, after taking three days, infant malaise symptoms and is voluntarily discontinued, and nearly one week, face in infant Color is pale, and appetite is poor, and love such as is cry and screamed at the symptom, and in 2012, you are to our hospital for that October 8.Check:Infant face is pale, skin No xanthochromia, defecation is normal, blood routine examination:Hb62 g/L, WBC 4.3 × 109/ L, RBC 3.0 × 1012/ L, Plt 154 × 109/ L, mean corpuscular volume (MCV)(MCV)74fL, 6 μm of ol/L of serum levels of iron.It is diagnosed as iron deficiency anemia.
Take the health care medicated diet that the present embodiment gained treats iron deficiency anemia, instructions of taking is:The daily morning and evening is each once, often Secondary 150-200mL(Take the circumstances into consideration to add and subtract), it is within two weeks a course for the treatment of.After taking three courses for the treatment of, infant is had rosy cheeks, and appetite strengthens, red Cell substantially rises, and routine blood test all has improvement, and after continuing to take three courses for the treatment of, infant routine blood test recovers normal.
Embodiment 4 treats the health care medicated diet of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion (30g/ part):16 parts of Rhizoma Dioscoreae;12 parts of Herba potentillae fulgentis;12 parts of Colla Corii Asini;13 parts of Herba Begoniae Crassirostriss;9 parts of Herba Equiseties Hiemalis;10 parts of Radix Morinae Bulleyanae;14 parts of Fructus Mori;Cattle 14 parts of horse rattan;16 parts of Radix Ginseng;13 parts of Cortex Lycii;28 parts of Hepar Sus domestica;19 parts of southern Fructus Jujubae;22 parts of Herba Spinaciae.
The preparation method of the health care medicated diet for the treatment of iron deficiency anemia, step is as follows:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with mass concentration be 70% ethanol as solvent, do not had more than a powder 6cm, stood 48 minutes, Make solvent fully run through raw material medicated powder, open valve, percolation is carried out with the speed of 5mL/min, the amount of percolate to be collected is When 15 times of raw material medicated powder amount, stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, and spray drying gets dry extract Powder, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng and Fructus Mori and step(2)Raw material after process is placed in marmite, adds the clear water of 9 times of material quantities, military Fiery heated and boiled 14 minutes, turns small fire and stewes 80 minutes slowly, and during stewing, every 15 minutes, stirring once, obtains medicine soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 17 points Clock, stops working, adds a cover vexed 9 minutes, be seasoned according to personal like.
The eating method of gained health care medicated diet of the present invention is:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add Subtract), it is within two weeks a course for the treatment of.
Embodiment 5 treats the health care medicated diet of iron deficiency anemia, is prepared from by following bulk drugs, is weight portion (25g/ part):15.5 parts of Rhizoma Dioscoreae;11 parts of Herba potentillae fulgentis;11 parts of Colla Corii Asini;12 parts of Herba Begoniae Crassirostriss;8 parts of Herba Equiseties Hiemalis;9.5 parts of Radix Morinae Bulleyanae;Fructus Mori 12.5 Part;12.5 parts of Radix Seu Caulis Mucunae Sempervirentis;15 parts of Radix Ginseng;12 parts of Cortex Lycii;25 parts of Hepar Sus domestica;17.5 parts of southern Fructus Jujubae;20 parts of Herba Spinaciae.
The preparation method of the health care medicated diet for the treatment of iron deficiency anemia, step is as follows:
(1)Herba potentillae fulgentis, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Radix Seu Caulis Mucunae Sempervirentis and Cortex Lycii are placed in air drier, dry, pulverize into Fine powder, is subsequently placed in percolator, with mass concentration be 65% ethanol as solvent, do not had more than a powder 6cm, stood 39 minutes, Make solvent fully run through raw material medicated powder, open valve, percolation is carried out with the speed of 5mL/min, the amount of percolate to be collected is When 14 times of raw material medicated powder amount, stop percolation, filter, filtrate recycling ethanol, concentrating under reduced pressure becomes paste, and spray drying gets dry extract Powder, finely ground, standby;
(2)Rhizoma Dioscoreae is cleaned, peeling, shave;Hepar Sus domestica is cleaned, shave;Softened by baking on slow fire put by Colla Corii Asini, is cut into small pieces, Standby;
(3)By Radix Ginseng, Fructus Mori and southern Fructus Jujubae and step(2)Raw material after process is placed in marmite, adds the clear of 8 times of material quantities Water, intense fire heated and boiled 12 minutes, turn small fire and stew 70 minutes slowly, during stewing, every 15 minutes, stirring once, obtains Medicine soup;
(4)Step is added in above-mentioned medicine soup(1)Gained dried cream powder, is simultaneously introduced Herba Spinaciae section, continues small fire and decocts 15 points Clock minute, stops working, adds a cover vexed 8 minutes, be seasoned according to personal like.
The eating method of gained health care medicated diet of the present invention is:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add Subtract), it is within two weeks a course for the treatment of.
Test example 1 gained of the present invention treats the health care medicated diet of iron deficiency anemia(Embodiment 5)Clinical practice:
1 data and method
1.1 physical data
In October, 2010 in September, -2013, screens the Patients with iron deficiency anemia totally 335 accepted for medical treatment in 3 hospitals, wherein man Property patient 153, female patient 182, max age 65 years old, minimal ages 6 years old, 48.5 years old mean age.All patients are near Phase all no took chalybeate, excluded other diseases in the blood system.
1.2 diagnostic criteria
(1)Anemia is microcytic hypochromic:Male Hb < 120g/L, women Hb < 110g/L, anemia of pregnant woman Hb < 100g/L; MCV, 27pg, MCHC < 32%.
(2)There is the foundation of iron deficiency:Meet storage iron loss to the greatest extent(ID)Erythropoiesis(IDE)Diagnosis.
It is diagnosable that ID meets following either condition.1. serum ferritin < 12ug/L;2. bone marrow iron stain display bone marrow Granule can contaminate ferrum and disappear, and sideroblast is less than 15%.
1. IDE meets the diagnostic criteria of ID;2. serum levels of iron is less than 8.95umol/L, and total iron binding capacity raises > 64.44umol/L, Transferrin turation<15%;3. PEP/Hb > 4.5ug/ghb.
(3)There is the sideropenic cause of disease, iron in treatment is effective.
1.3 Therapeutic Method
All patients are randomly divided into experimental group and matched group, and two groups of patients are at aspects such as sex, age, severity of anemia all no Notable difference(P > 0.05), there is comparability.Wherein experimental group takes the health care medicinal that gained of the present invention treats iron deficiency anemia Meals, eating method:The daily morning and evening is each once, each 150-200mL(Take the circumstances into consideration to add and subtract), it is within two weeks a course for the treatment of.Observe five altogether The course for the treatment of.Matched group uses other drugs(As medicines such as ferrous lactate oral liquid, the embolium of ferrum and multidimensional iron oral liquids).
1.4 curative effect determinate standard
Reference《New Chinese medicine guideline of clinical investigations》Relevant criterion judges.
Cure:Clinical symptom disappearance, ferro concentration in serum, total iron binding capacity etc. recover normal;
Effective:Clinical symptoms are clearly better, and ferro concentration in serum, total iron binding capacity etc. are slightly less than normal value;
Effectively:Clinical symptoms are slightly alleviated, and anemia situation is slightly improved;
Invalid:Clinical symptoms and anemia are all no improved.(Total effective rate=cure rate+obvious effective rate+effective percentage)
1.5 therapeutic outcome
Result is as shown in table 1.
Table 1:Experimental group and the therapeutic outcome of matched group
Therapeutic effect:Experimental group total effective rate is 98.1%, and matched group total effective rate is 79.2%.It follows that experiment Group effect is substantially better than matched group.
The present invention is by Rhizoma Dioscoreae, Herba potentillae fulgentis, Colla Corii Asini, Herba Begoniae Crassirostriss, Herba Equiseties Hiemalis, Radix Morinae Bulleyanae, Fructus Mori, Radix Seu Caulis Mucunae Sempervirentis, Radix Ginseng, Cortex Lycii, pig Totally 13 taste primary raw material medicines are prepared from for liver, southern Fructus Jujubae and Herba Spinaciae.Fang Zhong, Rhizoma Dioscoreae spleen reinforcing nourishing the stomach, engender liquid and benefic lung;Colla Corii Asini YIN nourishing is mended Blood;Radix Morinae Bulleyanae fills blood, and connects muscles and bones;Fructus Mori tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow liquid;Radix Seu Caulis Mucunae Sempervirentis promoting blood flow to regulate menstruation;Enrich blood relaxing muscles and tendons;The big benefit of Radix Ginseng Vigour, Gu de- promote the production of body fluid;Hepar Sus domestica, Herba Spinaciae tonifying liver, blood-nourishing;Fructus Jujubae spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid.All medicine compatibilities, bring out the best in each other, play altogether Spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, the work(of nourishing YIN and supplementing blood.After three courses for the treatment of of treatment, experimental group total effective rate is 98.1%, evident in efficacy.
It should be pointed out that the specific embodiment more representational example that is the present invention is it is clear that the skill of the present invention Art scheme is not limited to above-described embodiment, can also have many variations.Those of ordinary skill in the art, clearly public with present invention institute What what written description that open or according to file was undoubted obtained, all it is considered as this patent scope of the claimed.

Claims (1)

1. the health care medicated diet for the treatment of iron deficiency anemia, it is characterised in that being prepared from by following bulk drugs, is weight portion:Mountain Medicine 15.5;Herba potentillae fulgentis 11;Colla Corii Asini 11;Herba Begoniae Crassirostriss 12;Herba Equiseties Hiemalis 8;Radix Morinae Bulleyanae 9.5;Fructus Mori 12.5;Radix Seu Caulis Mucunae Sempervirentis 12.5;Radix Ginseng 15;Ground bone Skin 12;Hepar Sus domestica 25;Southern Fructus Jujubae 17.5;Herba Spinaciae 20.
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