CN104825563B - A kind of Chinese medicine preparation treating cervical spondylosis and preparation method thereof - Google Patents

Abstract

The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation treating cervical spondylosis and preparation method thereof.The preparation of the present invention includes the weight proportion of following raw material of Chinese medicine and each raw material and is respectively as follows: Radix Astragali 10-40g, Radix Puerariae 10-40g, Rhizoma Corydalis 10-40g, Rhizoma Et Radix Notopterygii 10-40g, Radix Saposhnikoviae 10-40g, Herba Asari 3-6g, Radix Angelicae Dahuricae 10-40g, Agkistrodon 10-40g, Squama Manis 10-40g, Scorpio 10-40g, Scolopendra 10-40g, Radix Angelicae Sinensis 10-40g, Radix Paeoniae Alba 10-40g, Rhizoma Chuanxiong 10-40g, Radix Notoginseng 10-40g, Flos Carthami 10-40g, Radix Salviae Miltiorrhizae 10-40g, Cortex Eucommiae (parched) 10-40g, Rhizoma Drynariae 10-40g, Cornu Cervi Pantotrichum 10-40g, Carapax et Plastrum Testudinis 10-40g, Cortex Cinnamomi 10-40g, Radix Glycyrrhizae 10-40g.The preparation process of medicament of the present invention is: step 1, medicine oven drying at low temperature；Step 2, medicine mix after pulverizing and sieving；Step 3, to hybrid medicine sterilization, be packaged into bag.The invention have benefit that, fundamentally the recurrence for the treatment of cervical spondylosis and pre-preventing cervical spondylosis, has promoting blood circulation, dredging meridian and relieving pain concurrently, the merit of liver and kidney tonifying.

Description

A kind of traditional Chinese medicine preparation for treating cervical spondylosis and preparation method thereof

technical field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating cervical spondylosis and a preparation method thereof.

Background technique

The degenerative changes of cervical intervertebral disc tissue and its secondary pathological changes involve the surrounding tissue structures (nerve root, spinal cord, vertebral artery, sympathetic nerve, etc.), and those with corresponding clinical manifestations are called cervical spondylosis. Cervical spondylosis is a common and frequently-occurring disease in orthopedic clinics. Patients with mild neck and shoulder pain, dizziness and headache, severe pain or limb weakness, and even sudden fainting, have seriously affected people's healthy life. Western medicine diagnosis and pathological classification: 1. Local type: occipital neck pain, limited neck movement, stiff neck muscles, limited head and neck at a certain position, and significant tenderness on both sides of the neck. X-ray films showed changes in the physiological curvature of the cervical spine. 2. Nerve root type: neck and shoulder pain, soreness in the occipital and back of the neck, radiating to the upper extremities, mild pain is distending pain, severe pain is like acupuncture and knife cutting, skin sensation in the innervated area of the affected nerve is decreased, neck muscles are tense, there is Significant tenderness points, positive arm and pressure head test. X-ray films showed stenosis or hyperplasia of the diseased intervertebral space, and the intervertebral foramen became smaller. MRI showed vegetation and nerve root canal narrowing behind the vertebral body. 3. Spinal cord type: mainly occurs in 40 to 60 years old, neck and shoulder pain may not be necessary, may feel a little discomfort, small hand movements malfunction, gait instability, pathological reflexes may appear, severe cases may have difficulty walking, urinary incontinence or urinary retention. X-ray films showed stenosis of diseased intervertebral disc and hyperplasia of vertebral body. MRI showed narrowing of the spinal canal, severe hyperplasia of the posterior border of the vertebral body and protruding into the spinal canal. 4. Vertebral artery type: headache, dizziness, tinnitus, dizziness, memory loss, occasional facial and eye symptoms, dizziness caused by head rotation, or even cataplexy. Oblique x-ray film shows the lateral protrusion of the uncinate joint, and vertebral arteriography shows distortion or stenosis. 5. Sympathetic nerve type: symptoms of sympathetic nerve excitation or inhibition, X-ray films show hyperplasia of uncinate vertebrae, narrowing of intervertebral foramina, changes in the physiological curvature of the cervical spine, and compression of the vertebral arteriography. 6. Mixed type: There are more than two kinds of oppressive symptoms.

For cervical spondylosis, there are many treatments. Physiotherapy includes traction therapy, massage therapy, hyperthermia, magnetic therapy, etc. using various machines, which are only local treatments, but cannot be adjusted as a whole, and the effect is not ideal; It can only relieve symptoms; although there are also oral medicines, they are highly toxic and should not be taken for a long time. Surgical therapy, traumatic, high risk, patients are not easy to accept; Western medicine therapy, mainly non-steroidal anti-inflammatory painkillers, due to side effects, patients are not easy to accept. Therefore, there is an urgent need for a drug with definite curative effect, low toxicity and side effects, and suitable for long-term use.

Contents of the invention

Aiming at the deficiencies of the prior art, the invention provides a traditional Chinese medicine preparation for treating cervical spondylosis with quick effect, high cure rate and no side effects and a preparation method thereof.

The invention provides a Chinese medicine preparation for treating cervical spondylosis, which comprises the following Chinese medicine raw materials and the weight ratio of each raw material is respectively: 10-40g of Astragalus, 10-40g of Pueraria Radix, 10-40g of Corydalis Corydalis, 10-40g of Notopterygium, and 10-40g of Fangfeng , Asarum 3-6g, Angelica dahurica 10-40g, Viper 10-40g, Pangolin 10-40g, Scorpion 10-40g, Centipede 10-40g, Angelica 10-40g, Baishao 10-40g, Chuanxiong 10-40g, Panax notoginseng 10-40g, safflower 10-40g, salvia miltiorrhiza 10-40g, fried Eucommia 10-40g, drynaria drynaria 10-40g, antler 10-40g, tortoise shell 10-40g, cinnamon 10-40g, licorice 10-40g.

Further, the following traditional Chinese medicine raw materials are included and the weight proportions of each raw material are respectively: Astragalus 20-40g, Pueraria 20-40g, Corydalis Corydalis 20-40g, Notopterygium 20-40g, Fangfeng 20-40g, Asarum 3-5g, Angelica dahurica 20g -40g, Viper 20-40g, Pangolin 20-40g, Scorpion 20-40g, Centipede 20-40g, Angelica 20-40g, Paeoniae Alba 20-40g, Rhizoma Chuanxiong 20-40g, Panax notoginseng 20-40g, Safflower 20g -40g, Danshen 20-40g, Fried Eucommia 20-40g, Rhizoma Drynariae 20-40g, Antler 20-40g, Tortoise shell 20-40g, Cinnamon 20-40g, Licorice 20-40g.

Further, the following traditional Chinese medicine raw materials are included and the weight proportions of each raw material are respectively: Astragalus 20-30g, Pueraria 20-30g, Corydalis Corydalis 20-30g, Notopterygium 20-30g, Fangfeng 20-30g, Asarum 3-4g, Angelica dahurica 20g -30g, Viper 20-30g, Pangolin 20-30g, Scorpion 20-30g, Centipede 20-30g, Angelica 20-30g, Paeoniae Alba 20-30g, Rhizoma Chuanxiong 20-30g, Panax notoginseng 20-30g, Safflower 20g -30g, Salvia miltiorrhiza 20-30g, fried Eucommia 20-30g, Drynaria rhizome 20-30g, antler 20-30g, turtle shell 20-30g, cinnamon 20-30g, licorice 20-30g.

Further, the parts by weight of each raw material are preferably: 20g of Radix Astragali, 20g of Pueraria Radix, 20g of Corydalis Corydalis, 20g of Notopterygium, 20g of Fangfeng, 3g of Asarum, 20g of Angelica dahurica, 20g of Viper, 20g of Pangolin, 20g of Scorpion, and 20g of Centipede , Angelica 20g, white peony root 20g, Chuanxiong 20g, notoginseng 20g, safflower 20g, salvia miltiorrhiza 20g, fried Eucommia 20g, Drynaria fortunei 20g, antler 20g, turtle shell 20g, cinnamon 20g, licorice 20g.

The traditional Chinese medicine formulation of the present invention is made into any clinically acceptable preparation according to conventional methods, such as powder, pill, tablet, capsule, granule, patch or ointment. According to the needs of different preparations, you can choose to add corresponding conventional excipients.

The present invention also provides a preparation method of a traditional Chinese medicine preparation for treating cervical spondylosis, using the raw materials of the weight ratio provided by the present invention, the preparation steps are:

Step 1, drying the above-mentioned raw materials at low temperature respectively;

Step 2, the dried raw materials in step 1 are pulverized with a pulverizer until they can pass through a 300-mesh sieve, and all the pulverized raw materials are mixed evenly;

Step 3. Sterilize and sterilize the mixed raw materials in step 2, and then evenly distribute them into bags. The number of divided bags varies according to the amount of medicine used, generally between 40-120 bags.

The method of administering the traditional Chinese medicine preparation provided by the present invention is to take 1 bag each morning and evening after meals, and take it with rice wine. One month is a course of treatment, and the medicine is stopped for 7 days between each course of treatment. During the period of medication, avoid hot and cold .

Cervical spondylosis generally can be cured after taking 1-2 courses of treatment, and can be cured after taking 3 courses of treatment for particularly serious cervical spondylosis.

The medicament composition of the present invention is formulated according to the theory of traditional Chinese medicine: kidney governs bones, liver governs tendons, and is prepared in combination with long-term clinical practice. Medical theory believes that deficiency of liver and kidney, deficiency of Qi and blood, and feeling of wind, cold and dampness at the same time, leading to meridian block are the fundamental pathogenesis of cervical spondylosis. The composition of the medicine of the present invention is completed on the basis of a profound understanding of the etiology and pathogenesis of cervical spondylosis:

In the prescription, Qi snake dispels wind, dredges collaterals, and relieves convulsions;

Pangolin promotes blood circulation and eliminates syndrome, promotes menstruation, breast milk, reduces swelling and discharges pus;

Scorpion and centipede relieve wind and relieve convulsions, attack poison and dissipate stagnation, dredge collaterals and relieve pain;

The combination of the above four medicines has the functions of promoting blood circulation, removing blood stasis, dredging collaterals and relieving pain, which is in line with what Ye Tianshi said: when a chronic disease enters the collaterals, insect medicine must be used to dredge collaterals, activate blood circulation and relieve pain.

Panax notoginseng promotes blood circulation and removes blood stasis to reduce swelling and relieve pain. It is a good product for treating various syndromes of blood stasis.

Safflower, Danshen promotes blood circulation, stimulates menstrual flow, dispels blood stasis and relieves pain;

Angelica tonifies blood and regulates menstruation, promotes blood circulation and relieves pain;

Paeoniae Alba nourishes blood and restrains yin, softens liver and relieves pain, and calms liver yang;

Ligusticum chuanxiong promotes blood circulation and promotes qi, dispels wind and relieves pain;

Corydalis activating blood, promoting qi and relieving pain,

The above seven medicines share the merit of promoting blood circulation, dredging collaterals and relieving pain of the monarch medicine, and are ministerial medicines altogether.

Astragalus invigorates the spleen, replenishes qi, invigorates the middle, and strengthens the body;

Pueraria lobata releases muscles, promotes body fluids and quenches thirst, and is good at treating stiff neck pain;

Notopterygium relieves exterior and cold, dispels wind and dampness, and relieves pain;

Herba Asarum relieves exterior and dispels cold, dispels wind and relieves pain;

Angelica dahurica relieves exterior and dispels cold, dispels wind and relieves pain;

The combination of the above six medicines has the effect of expelling wind, relieving exterior and dispelling cold without injuring exterior, and is an adjuvant medicine in the prescription.

Stir-fried Eucommia nourishes liver and kidney, strengthens bones and muscles;

Rhizoma drynaria invigorates blood circulation, invigorates kidneys and strengthens bones;

Antler nourishes kidney yang, nourishes essence and blood, and strengthens muscles and bones;

Tortoise shell nourishes yin and suppresses yang, nourishes kidney and strengthens bones;

Cinnamon tonifies fire and supports yang, dispels cold and relieves pain, warms meridian and opens channels;

The above five herbs work together to invigorate the liver and kidney, strengthen the muscles and bones, warm the meridians and dispel cold, and are adjuvant drugs in the prescription.

Licorice relieves spasms, relieves pain, replenishes qi and invigorates the spleen, and is an adjuvant drug in prescriptions.

Modern pharmacological research shows that:

Astragalus can promote body metabolism, anti-fatigue, and promote the renewal of serum and liver proteins; it can improve the phenomenon of anemia animals; it can raise hypoglycemia and reduce hyperglycemia; it can excite breathing; it can enhance and regulate the immune function of the body and promote the interferon system It can improve the body's disease resistance; it has a slight inhibitory effect on cell lesions caused by influenza virus and other viruses, and has a protective effect on mice infected with influenza virus; it has a wide range of antibacterial effects; Astragalus in cell culture, It can significantly increase the number of cells, vigorous cell growth, and prolong life; it can enhance myocardial contractility, protect the cardiovascular system, resist arrhythmia, expand coronary arteries and peripheral blood vessels, lower blood pressure, reduce platelet adhesion, and reduce thrombosis; It has the effects of lowering blood fat, anti-aging, anti-hypoxia, anti-radiation, and protecting the liver.

Pueraria decoction, alcohol infusion, total flavonoids, daidzin, and puerarin can all resist acute myocardial ischemia caused by vasopressin; Pueraria total flavonoids can expand coronary vessels and cerebral blood vessels, increase coronary blood flow and cerebral blood flow. flow, reduce myocardial oxygen consumption, and increase oxygen supply; puerarin can directly dilate blood vessels, reduce peripheral resistance, and have a significant antihypertensive effect, which can better relieve the "neck tightness" symptoms of hypertensive patients; puerarin can improve microcirculation , Improve local micro blood flow, inhibit platelet aggregation.

Tetrahydropalmatine has significant analgesic, hypnotic, sedative and stable effects, and the analgesic effects of A and Uglysin are also more obvious, and have certain hypnotic, sedative and stable effects; alcohol extract can expand coronary arteries and reduce coronary artery disease. Arterial resistance, increase coronary blood flow, improve hypoxia resistance; total alkali can resist arrhythmia, anti-myocardial ischemia, expand peripheral blood vessels, lower blood pressure, slow down heart rate, and total alkali has the effect of anti-ulcer and inhibition of gastric secretion; B and ugine have the effect of relaxing muscles.

Notopterygium injection has analgesic and antipyretic effects, and has inhibitory effect on skin fungi and Brucella; the water-soluble part of notopterygium has anti-arrhythmia effect; volatile oil also has anti-inflammatory, analgesic and antipyretic effects, and can fight against Myocardial ischemia induced by vasopressin and increased myocardial trophic blood flow; inhibitory effect on delayed hypersensitivity in mice.

Fangfeng has antipyretic, anti-inflammatory, sedative, analgesic, anticonvulsant, and antiallergic effects. Fangfeng decoction has different degrees of inhibitory effects on Shigella, hemolytic streptococcus, etc.; and has the effect of enhancing the phagocytic function of mouse peritoneal macrophages.

Asarum volatile oil, water and alcohol extracts have antipyretic, anti-inflammatory, sedative, anticonvulsant and local anesthetic effects respectively; large doses of volatile oil can excite and then inhibit the central nervous system, showing certain toxic and side effects; It can resist respiratory depression caused by morphine; the racemic higenamine contained in it can strengthen the heart, dilate blood vessels, relax smooth muscle, enhance lipid metabolism and increase blood sugar; the contained safrole is highly toxic and is a carcinogen. easy to break.

A small amount of Angelica toxin can excite the central nervous system, increase blood pressure, and cause salivation and vomiting; a large amount can cause tonic convulsions, followed by general paralysis; Angelica can resist the inhibition of the central nervous system caused by snake venom; it has antipyretic and anti-inflammatory effects. , Analgesic, antispasmodic, anticancer effects.

Viper has sedative, hypnotic and analgesic effects; the injection has a significant antihypertensive effect; the water extract can activate the fibrinolytic system; the alcohol extract can enhance the phagocytosis of macrophages and significantly increase the clearance rate of charcoal particles.

Pangolin water decoction can significantly prolong the coagulation time of mice and rats and reduce blood viscosity; water extraction and alcohol precipitation agent can directly expand the blood vessel wall to reduce peripheral resistance and significantly increase the blood flow of femoral artery; water extract and alcohol extract have Anti-inflammatory effect, the water extract still has the effect of anti-myocardial hypoxia and increasing white blood cells.

Scorpio contains scorpion venom, which is a protein similar to snake venom neurotoxin. East Asian scorpion venom and the antiepileptic peptide (AEP) purified from crude venom have obvious antiepileptic effect; scorpion has antagonism to convulsions caused by strychnine, nicotine, pentylenetetrazol, etc.; scorpion extract It has the effect of inhibiting thrombosis and anticoagulation in animals; the scorpion body and scorpion tail preparations have obvious analgesic effects on animal body pain or visceral pain; the analgesic effect of scorpion tail is about 5 times stronger than that of scorpion body.

Centipede water extract has obvious anticonvulsion effect on strychnine-induced convulsions; centipede decoction can improve the microcirculation of mice, prolong coagulation time, reduce blood viscosity, and have obvious analgesic and anti-inflammatory effects.

Angelica volatile oil can resist the excitatory effect of adrenaline-pituitary hormone or histamine on the uterus; angelica water or alcohol-soluble non-volatile substances have an excitatory effect on the isolated uterus and strengthen the uterine contraction. When administered in large quantities or repeatedly , Even tetanic contraction may occur, and the effect of alcohol-soluble substances is stronger than that of water-soluble substances. In the perfusion experiment of the isolated toads’ heart, the decoction of this product containing volatile oil can significantly inhibit the contraction amplitude and contraction frequency; the extract of Angelica sinensis can significantly expand the coronary artery of the isolated guinea pig and increase the coronary blood flow; the anesthetized dog intravenously injects this product, the heart rate has no Significantly changed, coronary resistance and total peripheral resistance decreased, coronary blood flow increased significantly, myocardial oxygen consumption decreased significantly, cardiac output and cardiac index tended to increase; angelica neutral oil also had a significant effect on experimental myocardial ischemia Protective effect; angelica and its sodium ferulate have obvious antithrombotic effect; oral administration of angelica water extract to mice can significantly promote the production of hemoglobin and red blood cells.

The percentage of peritoneal macrophages and phagocytosis index of mice fed with Baishao water decoction were significantly higher than those of the control group; Baishao can promote the phagocytosis of mouse peritoneal macrophages; Baishao water decoction can antagonize the effect of cyclophosphamide on Inhibition of peripheral T lymphocytes in mice, making it return to normal levels, shows that Radix Paeoniae Alba can restore the cellular immune function in a low state; Radix Paeoniae Alba extract has obvious inhibitory effect on egg white acute inflammatory edema in rats, and has a significant effect on cotton Globulous granuloma has antiproliferative effect; Radix Paeoniae Alba has obvious analgesic effect to the writhing reaction that acetic acid causes, and the methanol compound of licorice is combined, and both have synergistic analgesic effect to acetic acid writhing reaction; The main component in Radix Paeoniae Alba Paeoniflorin has a good antispasmodic effect.

Ligustrazine can dilate coronary arteries, increase coronary blood flow, improve myocardial blood oxygen supply, and reduce myocardial oxygen consumption; Ligustrazine can dilate cerebral blood vessels, reduce vascular resistance, significantly increase brain and limb blood flow, and improve microcirculation ; It can reduce the surface activity of platelets, inhibit platelet aggregation, and prevent the formation of thrombus; the water decoction has a sedative effect on the central nervous system of animals, and has an obvious and long-lasting antihypertensive effect; it can accelerate the absorption of local hematoma in fractures and promote the formation of callus ; Anti-vitamin E deficiency; can inhibit a variety of bacillus; anti-histamine and choleretic effect.

Panax notoginseng can shorten bleeding and coagulation time, has anti-platelet aggregation and thrombolytic effects; can improve humoral immune function, and has analgesic, anti-inflammatory, anti-aging effects.

Safflower decoction, water extract, safflower yellow pigment, etc. can expand peripheral blood vessels and lower blood pressure; can inhibit platelet aggregation, enhance fibrinolysis, and reduce whole blood viscosity; injection, alcohol extract, safflower glycosides can Significantly improve hypoxia resistance and have protective effect on ischemic hypoxic encephalopathy; decoction has exciting effect on uterus and intestinal smooth muscle; safflower yellow has analgesic, sedative and anticonvulsant effects on central nervous system; in addition, Safflower alcohol extract and water extract have anti-inflammatory effect; safflower yellow pigment has immunosuppressive effect.

Danshen can dilate coronary arteries, increase coronary blood flow, improve myocardial ischemia, promote the recovery of myocardial ischemia or injury, and reduce the scope of myocardial infarction; it can improve hypoxia tolerance and protect hypoxic myocardium; it can improve microcirculation , promote blood flow; can expand blood vessels, lower blood pressure; can improve blood rheology, reduce blood viscosity, inhibit platelet and coagulation function, activate fibrinolysis, and resist thrombosis; can protect red blood cell membrane; can regulate blood lipids and inhibit atherosclerosis Plaque formation; can protect liver cell damage, promote liver cell regeneration, and have anti-hepatic fibrosis; can promote the healing of fractures and skin incisions; can protect gastric mucosa and resist gastric ulcer; have sedative and analgesic effects on the central nervous system ; It has the effect of improving renal function and protecting ischemic kidney injury; it has the effect of anti-inflammation and anti-allergy.

Eucommia bark can inhibit DNCB-induced delayed-type hypersensitivity in mice; it can resist the immunosuppressive effect of oxidative cortisone, and has the function of regulating cellular immune balance. The water decoctions of raw eucommia, fried eucommia and sand scalded eucommia have obvious antihypertensive effect on rabbits and dogs, but the antihypertensive effect of raw eucommia is weaker. The absolute value is equivalent to twice that of raw Eucommia.

Drynaria decoction and alcohol-precipitated liquid can prevent the increase of serum cholesterol and triglyceride, and prevent the formation of aortic atherosclerotic plaque; drynaria polysaccharides and drynaria flavone glycosides can lower blood fat and resist arteriosclerosis Rhizoma drynariae can promote bone to absorb calcium, increase blood calcium and blood phosphorus levels, and help fracture healing; improve chondrocytes and delay bone cell degeneration; in addition, drynaria flavone glycosides have Obvious sedative and analgesic effect.

Large doses of deer antler essence can reduce the range of contraction, slow down the heart rate, dilate peripheral blood vessels, and lower blood pressure. Moderate dose of deer antler essence can significantly enhance the activity of the isolated heart, increase the range of systole, and increase the heart rate, resulting in an increase in cardiac pulse output and percent output. Deer antler has obvious anti-lipid peroxidation and anti-stress effects.

Tortoise shell can improve the animal's "Yin Deficiency" syndrome pathological animal functional state, and make it return to normal; it can enhance immune function; it has the effect of bidirectionally regulating DNA synthesis rate; it has excitatory effect on both in vitro and in vivo uterus; it has antipyretic and blood enriching effects , sedative effect; there are anticoagulant, increase coronary flow and improve hypoxia resistance; tortoise shell glue has a certain role in increasing the number of white blood cells.

Cinnamon has the effects of dilating blood vessels, promoting blood circulation, enhancing coronary artery and cerebral blood flow, and reducing vascular resistance; in vitro, its methanol extract and cinnamon aldehyde have anti-platelet aggregation and anti-thrombin effects; cinnamon oil, cinnamon aldehyde 1. Sodium cinnamate has sedative, analgesic, antipyretic, anticonvulsant and other effects; cinnamon oil can promote intestinal motility, increase the secretion of digestive tract, enhance digestive function, eliminate gas accumulation in the digestive tract, relieve gastrointestinal spasmodic pain, and Cause uterine congestion; cinnamon water extract, ether extract can inhibit the formation of animal experimental gastric ulcer.

Licorice has antibacterial, antiviral, anti-inflammatory, anti-allergic effects; it has a detoxification effect similar to glucuronic acid on certain poisons; it has a similar effect to adrenal cortex hormone;

Compared with the prior art, the present invention is beneficial in that:

1. Promoting blood circulation, dredging collaterals and relieving pain, and has the function of nourishing liver and kidney.

2. The medicines used in the present invention are divided into four groups, one group is insect medicines: viper, pangolin, scorpion, and centipede, which conforms to what Ye Tianshi said: chronic diseases enter the collaterals, and insect medicines must be used to dredge collaterals, activate blood circulation and relieve pain. ; One group is medicine for promoting blood circulation and removing stasis: Panax notoginseng, safflower, salvia miltiorrhiza, angelica, white peony root, chuanxiong, and corydalis, which can strengthen the effect of insect medicines for dredging collaterals, promoting blood circulation and relieving pain; , Notopterygium, Fangfeng, Asarum, Angelica dahurica, combined with Astragalus can achieve the effect of expelling wind and cold, relieving the exterior without hurting the exterior; one group is medicine for nourishing the kidney, strengthening tendons and strengthening bones: fried Eucommia, drynaria, velvet antler, tortoise shell, cinnamon, It can invigorate the kidneys, strengthen the tendons and bones, fundamentally treat cervical spondylosis and prevent the recurrence of cervical spondylosis. The first three groups of medicines are medicines for treating the symptoms, and the fourth group of medicines are medicines for treating the root causes. All medicines are used in combination to achieve the purpose of treating both symptoms and root causes.

detailed description

Below in conjunction with specific embodiment the present invention is described in further detail,

Example 1:

The traditional Chinese medicine components in this example are prepared according to the following weight ratios: Astragalus 20g, Pueraria 20g, Corydalis 20g, Notopterygium 20g, Fangfeng 20g, Asarum 3g, Angelica dahurica 20g, Viper 20g, pangolin 20g, scorpion 20g, centipede 20g, angelica 20g, white peony root 20g, chuanxiong 20g, panax notoginseng 20g, safflower 20g, salvia miltiorrhiza 20g, fried Eucommia 20g, drynaria drynaria 20g, antler 20g, tortoise shell 20g, cinnamon 20g, licorice 20g.

In this embodiment, the preparation method of the medicine with the weight ratio is: first dry the above-mentioned medicine at low temperature, then pulverize the above thirteen herbs with a pulverizer until they can pass through a 300-mesh sieve, mix them evenly, and sterilize them. Divide the medicated noodles into 60 bags evenly.

The dosage form in this embodiment is made into any clinically acceptable preparation according to conventional methods, such as powder, pill, tablet, capsule, granule, patch or ointment. According to the needs of different preparations, you can choose to add corresponding conventional excipients.

The medication method of the traditional Chinese medicine preparation provided by the present embodiment is to take 1 bag each day after meals in the morning and evening, and take it with rice wine. One month is a course of treatment, and the medicine is stopped for 7 days between each course of treatment. cold. Cervical spondylosis generally can be cured after taking 1-2 courses of treatment, and can be cured after taking 3 courses of treatment for particularly serious cervical spondylosis.

Example 2:

The traditional Chinese medicine components in this example are prepared according to the following weight ratio: Astragalus 40g, Pueraria 40g, Corydalis 40g, Notopterygium 40g, Fangfeng 40g, Asarum 6g, Angelica dahurica 40g, Viper 40g, pangolin 40g, scorpion 40g, centipede 40g, angelica 40g, white peony 40g, chuanxiong 40g, notoginseng 40g, safflower 40g, salvia miltiorrhiza 40g, fried Eucommia 40g, drynaria drynaria 40g, antler 40g, turtle shell 40g, cinnamon 40g, licorice 40g.

In this embodiment, the preparation method of the medicine with the weight ratio is: first dry the above-mentioned medicine at low temperature, then pulverize the above thirteen herbs with a pulverizer until they can pass through a 300-mesh sieve, mix them evenly, and sterilize them. Divide the medicated noodles into 120 bags evenly.

Example 3:

The traditional Chinese medicine components in this example are prepared according to the following weight ratio: Astragalus 10g, Pueraria 10g, Corydalis 10g, Notopterygium 10g, Fangfeng 10g, Asarum 3g, Angelica dahurica 10g, Viper 10g, pangolin 10g, scorpion 10g, centipede 10g, angelica 10g, white peony root 10g, Chuanxiong 10g, notoginseng 10g, safflower 10g, salvia miltiorrhiza 10g, fried Eucommia 10g, Drynaria fortunei 10g, antler 10g, turtle shell 10g, cinnamon 10g, licorice 10g.

In this embodiment, the preparation method of the medicine with the weight ratio is: first dry the above-mentioned medicine at low temperature, then pulverize the above thirteen herbs with a pulverizer until they can pass through a 300-mesh sieve, mix them evenly, and sterilize them. Divide the medicated noodles into 40 bags evenly.

Example 4:

The traditional Chinese medicine components of this example are prepared according to the following weight ratio: Astragalus 23g, Pueraria 26g, Corydalis 27g, Notopterygium 25g, Fangfeng 23g, Asarum 4g, Angelica dahurica 22g, Viper 26g, pangolin 25g, scorpion 26g, centipede 24g, angelica 28g, white peony 25g, chuanxiong 22g, notoginseng 30g, safflower 24g, salvia miltiorrhiza 23g, fried eucommia 25g, drynaria 22g, antler 30g, turtle shell 24, cinnamon 30g, licorice 25g.

In this embodiment, the preparation method of the medicine with the weight ratio is: first dry the above-mentioned medicine at low temperature, then pulverize the above thirteen herbs with a pulverizer until they can pass through a 300-mesh sieve, mix them evenly, and sterilize them. Divide the medicated noodles into 80 bags evenly.

Example 5:

The traditional Chinese medicine components in this example are prepared according to the following weight ratio: Astragalus 37g, Pueraria 36g, Corydalis 33g, Notopterygium 35g, Fangfeng 30g, Asarum 5g, Angelica dahurica 32g, Viper 36g, pangolin 35g, scorpion 35g, centipede 36g, angelica 36g, white peony root 35g, chuanxiong 32g, notoginseng 38g, safflower 36g, salvia miltiorrhiza 32g, fried Eucommia 30g, drynaria drynaria 32g, antler 38g, turtle shell 33g, cinnamon 37g, licorice 36g.

In this embodiment, the preparation method of the medicine with the weight ratio is: first dry the above-mentioned medicine at low temperature, then pulverize the above thirteen herbs with a pulverizer until they can pass through a 300-mesh sieve, mix them evenly, and sterilize them. Divide the medicated noodles into 100 bags evenly.

The Chinese medicine form of embodiment 2-5 and the addition of adjuvant are all identical with embodiment 1.

The medication methods of the traditional Chinese medicine preparations provided in Examples 2-5 are all the same as in Example 1.

In the above examples, Herba Asarum, Viper, Scorpion, and Centipede are all poisonous products in the formula of the present invention. However, due to the synergistic and antagonistic effects of Chinese medicine compatibility, the toxicity can be reduced.

Carry out animal toxicity test and clinical application respectively to the embodiment provided by the present invention, find that medicine is nontoxic in animal toxicity test, all play good therapeutic effect clinically in each embodiment proportioning, below only utilize embodiment 1 proportioning The treatment is described in detail:

(1) Animal toxicity test

1. Acute toxicity test, using oral administration method

(1) Get 12g of medicine of the present invention and add water and grind to make the suspension (concentration is 300mg/ml) of full amount into 40ml for subsequent use.

(2) Get 20 Kunming mice (10 males and 10 males) with a body weight of (20 ± 2) g, and each mouse is given a sample suspension 40ml/kg orally (equivalent to 60 times the human dosage), and each Once a day, observed for 10 days, the mice survived healthily, without any toxic and side effects. After dissection, the blood picture, liver function, and the histomorphological findings of various organs were not different from those in the control group. The medicine of the present invention has a tolerance dose of more than 12 g/kg for oral administration to mice.

(3) Get 20 Kunming mice (10 males and 10 males) with a body weight of (20 ± 2) g, and each mouse is divided into groups (10 mice in each group) and administered with sample suspension 60ml/kg and 80ml/kg. Stomach (respectively equivalent to 90 times and 120 times the human dosage), once a day, observed for 10 days, the results showed that the two groups of mice survived healthily, without toxic and side effects, and observed the blood picture, liver function, and the morphology of various organs after dissection There was no difference in the findings compared with the control group. It can be seen that the maximum tolerated dose of the medicine of the present invention to mice is above 24g/kg.

2. Cumulative toxicity test, using oral administration method

(1) Get 6g of medicine of the present invention and add water and grind to make the suspension (concentration is 150mg/ml) of full amount into 40ml for subsequent use.

(2) Get 40 Kunming mice (20 females and 20 males) with a body weight of (20 ± 2) g, and each mouse is given a sample suspension 40ml/kg orally (equivalent to 30 times the human dosage), and each Once a day, observed for three months, the mice were healthy and survived without any side effects. The blood picture and liver function were observed after dissection. There is basically no accumulation in the body.

The acute toxicity test shows that the maximum tolerated dose of this drug to mice is above 24g/kg; the cumulative toxicity test on mice shows that the oral dose of 4g/kg has no accumulation, which is higher than the planned dosage of clinical adults by 24g/kg. 0.20g/kg. This drug is safe for patients.

(2) Clinical application

1. Clinical diagnostic criteria

All patients were confirmed by X-ray photos or CT examination, combined with the analysis of patients' symptoms.

2. Clinical data

The 600 cases were all outpatients, and all cases met the criteria for judging cervical spondylosis in "Practical Diagnosis and Therapeutics of Integrative Traditional Chinese and Western Medicine" (Chen Guiyan, Yang Sipeng. Practical Diagnosis and Therapeutics of Integrative Traditional Chinese and Western Medicine). The patients were randomly divided into two groups. The treatment group consisted of 300 cases, 180 males and 120 females; the youngest was 25 years old, and the oldest was 65 years old. The course of disease ranged from 3 months to 10 years. There were 300 cases in the control group, including 190 males and 110 females; the youngest was 24 years old, the oldest was 66 years old, and the course of disease was 4 months to 10 years; there was no significant difference in gender, age, and course of disease between the two groups (P> 0.05), which are comparable.

3. Treatment method

The treatment group is given the medicine of the present invention orally, and takes one pack respectively after meals in the morning and evening every day, and takes it with rice wine. The control group was given Jingfukang Granules orally, 2 bags at a time, twice a day, with warm water after meals in the morning and evening. One month as one course of treatment in both groups, and the curative effect was observed after 2 courses of treatment.

4. Evaluating Criteria for Efficacy

Refer to the Chinese Medicine Industry Standard of the People's Republic of China "Standards for Diagnosis and Curative Effect of Diseases of Traditional Chinese Medicine".

Cured: the original symptoms disappear, muscle strength is normal, neck and limb functions return to normal, and can participate in normal labor and work;

Improvement: the original symptoms are relieved, muscle strength is normal, neck, shoulder and back pain are relieved, and neck and limb functions are improved;

Unhealed: Symptoms have not improved.

5. Treatment results

group no cure efficient invalid Total effective rate% therapy group 300 260* 30 10 96.67* control group 300 40 90 200 43.33

In the table, * means P<0.01 between the treatment group and the control group by χ ² test.

As can be seen from the above table, the curative effect of the medicine of the present invention is obviously better than Jingfukang Granules.

6. As can be seen from the discussion of the above technical solutions, the drug function of the present invention is to activate blood circulation, dredge collaterals and relieve pain, and has the function of nourishing the liver and kidney. The medicines used in the present invention are divided into four groups, one group is insect medicines: viper, pangolin, scorpion and centipede, which is in line with what Ye Tianshi said: chronic illness enters the collaterals, and insect medicine must be used to dredge collaterals, activate blood circulation and relieve pain; One group is blood-activating and stasis-removing drugs: Panax notoginseng, safflower, salvia, angelica, white peony root, chuanxiong, and corydalis, which can strengthen the effect of insect medicines on dredging collaterals, promoting blood circulation and relieving pain; one group is expelling wind and cold-relieving drugs: kudzu root, notopterygium , Fangfeng, Asarum, Angelica dahurica, combined with Astragalus can achieve the effect of expelling wind and cold, relieving the exterior without hurting the exterior; one group is kidney-tonifying, tendon-building and bone-building medicine: fried Eucommia, drynaria, antler, tortoise shell, and cinnamon, which can nourish the kidney Strengthen tendons and bones, fundamentally treat cervical spondylosis and prevent recurrence of cervical spondylosis. The first three groups of medicines are medicines for treating the symptoms, and the fourth group of medicines are medicines for treating the root cause. All medicines are used in combination to achieve the purpose of treating both symptoms and root causes, and have significant curative effects. Moreover, it has the characteristics of low treatment cost, fast curative effect, less pain for patients, etc., and has a good prospect of popularization and application.

7. Typical cases:

Example 1 Cai, male, 28 years old, from Laishan District, Yantai City, Shandong Province. Symptoms are: flaccidity and weakness of limbs, unable to take care of oneself for more than a year, diagnosed as C4-C7 node hyperplasia by hospital CT examination, oppressing nerves. Examined on August 26th, 2006, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 2 Zhong Mou, male, 42 years old, from Jinan City, Shandong Province. Suffering from cervical spondylosis for 2 years, neck pain, right hand numbness, dizziness and headache. Crackling when twisting the neck. Examine on April 6th, 2002, through drug treatment of the present invention, fully recover after 2 courses for the treatment of. Follow up a case by regular visits to so far without recurrence.

Example 3 Sun, female, 40 years old, from Laishan District, Yantai City, Shandong Province. Neck pain, dizziness, headache, blurred vision. It was diagnosed as C3～C7 node hyperplasia, spinal canal stenosis, and cerebral blood supply insufficiency through hospital CT examination. Examine on March 5th, 2004, through drug treatment of the present invention, fully recover after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 4 Zhao, female, 38 years old, is from Zhifu District, Yantai City, Shandong Province. Neck, shoulder, and back pain, numbness and soreness in both hands for more than 7 months, and a large amount of western medicine was ineffective. Recently, the pain has increased, especially at night, restlessness, and limited neck movement. The left side of the neck was stiff, and the pain was aggravated when the neck was moved. The tenderness of the 4th to 7th cervical vertebra was obvious. The neck pressure test (+), the brachial plexus stretch test (+). X-ray films showed: C4, C7 vertebral body hyperosteogeny, bilateral uncinate joint space unequal width. Examined on August 9th, 2001, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 5 Cao, male, 56 years old, was born in Dongzhuang Township, Qufu City, Shandong Province. Patient's neck, shoulder, occipital pain for more than 3 years, headache and dizziness for 1 year. In the recent period, the condition has worsened, the neck is stiff, the side cannot be turned well, the vision is blurred, and positional vertigo often occurs. The treatment effect of Chinese and Western medicine is not good. On September 12, 2002, I came to the clinic, and the inspection and diagnosis: the tenderness of the spinous processes of the 3rd to 7th cervical vertebrae was obvious, the neck pressure test (+), and the brachial plexus traction test (+). X-ray films showed that the physiological curvature of the cervical spine became straight, the anterior edges of C4, C5, and C6 vertebral bodies showed lip-tooth hyperplasia, and the intervertebral space between C5 and C6 was narrowed. After 2 courses of treatment, all symptoms were eliminated after medicament treatment of the present invention, and the functional activities of the neck and limbs all returned to normal. Follow up a case by regular visits to so far without recurrence.

Example 6 Yuan, male, 48 years old, from Binzhou City, Shandong Province. Suffering from cervical spondylosis for 2 years, treated in Yantai Traditional Chinese Medicine Hospital for 3 months, no obvious improvement. Examined on October 9th, 2004, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 7 Wang, female, 43 years old, from Dongzhuang Township, Qufu City, Shandong Province. She had persistent neck and back pain with paroxysmal aggravation for 1 year, and had received various treatments with no obvious effect. On July 9, 2005, I came to the clinic. The physical examination showed that the neck was stiff, and the pain aggravated when the neck was moved and the movement was obviously limited. Through drug treatment of the present invention, recovery from illness after 2 courses of treatment. The X-ray films of the cervical region were taken to compare the changes of the imaging studies. The physiological curvature of the cervical region was slightly kyphosis before the treatment, and the physiological curvature returned to normal after the treatment. Follow up a case by regular visits to so far without recurrence.

Example 8 Kong X, male, 40 years old, from Dongzhuang Township, Qufu City, Shandong Province. Suffering from cervical spondylosis for more than two years, shoulder pain, dizziness, neck stiffness and pain, numbness and pain in both upper limbs. Once done neck collar traction, massage and other treatments, but the symptoms were not significantly relieved. Examine on June 7th, 2008, through drug treatment of the present invention, fully recover after 2 courses for the treatment of. Follow up a case by regular visits to so far without recurrence.

Example 9 Jiang, male, 58 years old, from Zhifu District, Yantai City, Shandong Province. The patient suffered from neck, shoulder and back pain, headache, dizziness, stiff neck, and numb upper limbs, which seriously affected work and life. Hospital X-ray film, diagnosed as: cervical spondylosis. Once took various medicines, still do not take a turn for the better, the state of an illness constantly increases the weight of. Examine on April 7th, 2010, through drug treatment of the present invention, fully recover after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 10 Zhang, male, 29 years old, was born in Laishan District, Yantai City, Shandong Province. The patient was diagnosed with cervical spinal canal stenosis by CT, with unbearable neck pain, numbness and pain in the upper limbs, dizziness, unable to twist the head, and unable to participate in work. He has been ill for 2 years, and the treatment effects of cervical traction, massage, and medication are not obvious. Examine on June 9th, 2011, through drug treatment of the present invention, fully recover after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 11 Shen, male, 49 years old, was born in Laishan District, Yantai City, Shandong Province. The patient had neck and shoulder pain for 2 days, and then aggravated to the point that the head could not turn or turned to one side, the neck muscles were tense, and there was obvious tenderness. On the X-ray film, the curve of the cervical spine disappeared and became straight. Examine on September 11th, 2012, through drug treatment of the present invention, fully recover after 1 course of treatment. Follow up a case by regular visits to so far without recurrence.

Example 12 Lee, female, 50 years old, from Laishan District, Yantai City, Shandong Province. Long-term neck pain, accompanied by symptoms such as headache, dizziness, insomnia, nausea, and vomiting, was diagnosed as vertebral artery type cervical spondylosis two years ago. Multiple treatments are ineffective. Examined on November 9th, 2010, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 13 Zhao, male, 62 years old, from Zhifu District, Yantai City, Shandong Province. He was admitted to the hospital for sudden dizziness, neck stiffness, and precordial pain, and was diagnosed with cervical stenosis, joints, cartilage, ligaments, and muscles were damaged by film examination. The main reasons are long-term desk work and heavy blows to the head and neck. Examine on March 11th, 2011, through drug treatment of the present invention, fully recover after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 14 Wang, female, 57 years old, from Wangzhuang Township, Qufu City, Shandong Province. The patient had neck, shoulder and back pain, limited neck movement, sensory disturbance, muscle weakness, and muscle atrophy in the affected limbs, brachial plexus stretch test (+), neck compression test (+), and was diagnosed as cervical spondylotic radiculopathy. The course of the disease was 3 years, and the treatment effects such as cervical traction, massage, and medication were not obvious. Examined on September 8th, 2012, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 15 Zhao, female, 36 years old, is from Dongzhuang Township, Qufu City, Shandong Province. Weakness and numbness of both lower limbs, gradually unsteady gait, difficulty walking, increased limb muscle tension, hyperreflexia of tendons, headache and dizziness at the same time, diagnosed as mixed cervical spondylosis of spinal cord type and sympathetic type, course of disease 2 year. Examine on February 28th, 2010, through drug treatment of the present invention, fully recover after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 16 Han, male, 44 years old, from Laishan District, Yantai City, Shandong Province. February of onset, neck pain, occasional dizziness, aggravated by movement, numbness and discomfort in both upper limbs, neck compression test (+). Check the X-ray film and show: C4-5, C5-6, C6-7 intervertebral disc herniation. Diagnosed as "cervical spondylosis". Examine on October 6th, 2009, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 17 Li, female, 46 years old, from Binzhou City, Shandong Province. Ten years after the onset, the pain in the neck and left shoulder was aggravated by exertion and relieved by rest. The pain in the left upper limb was accompanied by numbness of the left middle finger joint and distal finger joint, and Hoffmann's sign was bilaterally positive. Check MRI shows: C5-6 intervertebral disc left kyphosis. The X-ray films showed that the physiological curvature of the cervical spine became shallower, and some intervertebral foramina on both sides had slightly protruding osteophytes. Diagnosed as "cervical spondylosis". Examined on June 7th, 2008, through drug treatment of the present invention, recovery from illness after 2 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 18 Dong Mou, male, 42 years old, from Shijiazhuang City, Hebei Province. The onset of 13 years, neck stiffness, occasional dizziness, numbness and weakness of limbs, increased fatigue, relief after rest, neck pressure test (+), cervical spinous process tenderness. The X-ray film showed that the physiological curvature of the cervical spine became straight, and there was a slight protruding osteophyte in the left part of the intervertebral foramen. Diagnosed as "cervical spondylosis". Examined on September 16th, 2009, through drug treatment of the present invention, recovery from illness after 3 courses of treatment. Follow up a case by regular visits to so far without recurrence.

Example 19 Zheng, male, 61 years old, from Hangzhou City, Zhejiang Province. Suffering from cervical spondylotic radiculopathy for 2 years, the spinous processes of C3-C7 all have different degrees of pressure pain, the neck pain is aggravated when stretching back, there is neck noise when the neck is turned, pain is felt when the left and right shoulder joints are moved, and sometimes finger Tip numbness, neck compression test (+), brachial plexus traction test (+). Examine on July 18th, 2009, through drug treatment of the present invention, fully recover after 1 course of treatment. Follow up a case by regular visits to so far without recurrence.

Example 20 Zhang, male, 45 years old, from Qufu City, Shandong Province. Suffering from neck-type cervical spondylosis, neck pain radiating to the shoulders, numbness and weakness of upper limbs, aggravated after activities, Chinese and Western medicine treatment has no obvious effect for more than two years. Examine on March 18th, 2006, through drug treatment of the present invention, fully recover after 2 courses for the treatment of. Follow up a case by regular visits to so far without recurrence.

It will be apparent to those skilled in the art that the invention is not limited to the details of the above-described exemplary embodiments, but that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Accordingly, the embodiments should be regarded in all points of view as exemplary and not restrictive, the scope of the invention being defined by the appended claims rather than the foregoing description, and it is therefore intended that the scope of the invention be defined by the appended claims rather than by the foregoing description. All changes within the meaning and range of equivalents of the elements are embraced in the present invention.

In addition, it should be understood that although this specification is described according to implementation modes, not each implementation mode includes an independent technical solution, and this description in the specification is only for clarity, and those skilled in the art should take the specification as a whole, The technical solutions in the various embodiments can also be properly combined to form other implementations that can be understood by those skilled in the art.

Claims (7)

1. the Chinese medicine preparation treating cervical spondylosis, it is characterized in that, it is made up of following raw material of Chinese medicine, and the weight proportion of each raw material of Chinese medicine is respectively as follows: Radix Astragali 10-40g, Radix Puerariae 10-40g, Rhizoma Corydalis 10-40g, Rhizoma Et Radix Notopterygii 10-40g, Radix Saposhnikoviae 10-40g, Herba Asari 3-6g, Radix Angelicae Dahuricae 10-40g, Agkistrodon 10-40g, Squama Manis 10-40g, Scorpio 10-40g, Scolopendra 10-40g, Radix Angelicae Sinensis 10-40g, Radix Paeoniae Alba 10-40g, Rhizoma Chuanxiong 10-40g, Radix Notoginseng 10-40g, Flos Carthami 10-40g, Radix Salviae Miltiorrhizae 10-40g, Cortex Eucommiae (parched) 10-40g, Rhizoma Drynariae 10-40g, Cornu Cervi Pantotrichum 10-40g, Carapax et Plastrum Testudinis 10-40g, Cortex Cinnamomi 10-40g, Radix Glycyrrhizae 10-40g.

null2. a kind of Chinese medicine preparation treating cervical spondylosis according to claim 1，It is characterized in that，It is made up of following raw material of Chinese medicine，And the weight proportion of each raw material of Chinese medicine is respectively as follows: Radix Astragali 20-40g、Radix Puerariae 20-40g、Rhizoma Corydalis 20-40g、Rhizoma Et Radix Notopterygii 20-40g、Radix Saposhnikoviae 20-40g、Herba Asari 3-5g、Radix Angelicae Dahuricae 20-40g、Agkistrodon 20-40g、Squama Manis 20-40g、Scorpio 20-40g、Scolopendra 20-40g、Radix Angelicae Sinensis 20-40g、Radix Paeoniae Alba 20-40g、Rhizoma Chuanxiong 20-40g、Radix Notoginseng 20-40g、Flos Carthami 20-40g、Radix Salviae Miltiorrhizae 20-40g、Cortex Eucommiae (parched) 20-40g、Rhizoma Drynariae 20-40g、Cornu Cervi Pantotrichum 20-40g、Carapax et Plastrum Testudinis 20-40g、Cortex Cinnamomi 20-40g、Radix Glycyrrhizae 20-40g.

null3. a kind of Chinese medicine preparation treating cervical spondylosis according to claim 1，It is characterized in that，It is made up of following raw material of Chinese medicine，And the weight proportion of each raw material of Chinese medicine is respectively as follows: Radix Astragali 20-30g、Radix Puerariae 20-30g、Rhizoma Corydalis 20-30g、Rhizoma Et Radix Notopterygii 20-30g、Radix Saposhnikoviae 20-30g、Herba Asari 3-4g、Radix Angelicae Dahuricae 20-30g、Agkistrodon 20-30g、Squama Manis 20-30g、Scorpio 20-30g、Scolopendra 20-30g、Radix Angelicae Sinensis 20-30g、Radix Paeoniae Alba 20-30g、Rhizoma Chuanxiong 20-30g、Radix Notoginseng 20-30g、Flos Carthami 20-30g、Radix Salviae Miltiorrhizae 20-30g、Cortex Eucommiae (parched) 20-30g、Rhizoma Drynariae 20-30g、Cornu Cervi Pantotrichum 20-30g、Carapax et Plastrum Testudinis 20-30g、Cortex Cinnamomi 20-30g、Radix Glycyrrhizae 20-30g.

4. a kind of Chinese medicine preparation treating cervical spondylosis according to any one of claim 1-3, it is characterized in that, it is made up of following raw material of Chinese medicine, and the weight proportion of each raw material of Chinese medicine is respectively as follows: Radix Astragali 20g, Radix Puerariae 20g, Rhizoma Corydalis 20g, Rhizoma Et Radix Notopterygii 20g, Radix Saposhnikoviae 20g, Herba Asari 3g, Radix Angelicae Dahuricae 20g, Agkistrodon 20g, Squama Manis 20g, Scorpio 20g, Scolopendra 20g, Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 20g, Rhizoma Chuanxiong 20g, Radix Notoginseng 20g, Flos Carthami 20g, Radix Salviae Miltiorrhizae 20g, Cortex Eucommiae (parched) 20g, Rhizoma Drynariae 20g, Cornu Cervi Pantotrichum 20g, Carapax et Plastrum Testudinis 20, Cortex Cinnamomi 20g, Radix Glycyrrhizae 20g.

5. a kind of Chinese medicine preparation treating cervical spondylosis according to claim 4, it is characterised in that: the dosage form that described Chinese medicine adopts is pharmaceutically acceptable dosage form.

6. a kind of Chinese medicine preparation treating cervical spondylosis according to claim 5, it is characterised in that: the dosage form that described Chinese medicine adopts is powder, pill, tablet, capsule, granule, patch or ointment.

7. the preparation method of the Chinese medicine preparation of a treatment cervical spondylosis as claimed in claim 1, it is characterised in that concrete preparation process is:

Step 1, by the raw material oven drying at low temperature described in claim 1；

Step 2, step 1 is dried after raw material, be crushed to respectively with pulverizer can cross 300 mesh sieves, by all pulverize after raw material mix homogeneously；

Step 3, the raw material sterilization that will mix in step 2, average mark dresses up bag afterwards.