CN104524359B - 一种中药组合物、其制备方法及应用 - Google Patents
一种中药组合物、其制备方法及应用 Download PDFInfo
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- CN104524359B CN104524359B CN201410854702.6A CN201410854702A CN104524359B CN 104524359 B CN104524359 B CN 104524359B CN 201410854702 A CN201410854702 A CN 201410854702A CN 104524359 B CN104524359 B CN 104524359B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Natural Medicines & Medicinal Plants (AREA)
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- Alternative & Traditional Medicine (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
Description
组别 | 动物数(只) | 剂量 | 血糖含量(mmol/L) |
实施例1组 | 10 | 3.80g生药/kg | 10.78±1.13* |
比较例1组 | 10 | 3.80g生药/kg | 12.03±1.40 |
阳性对照组 | 10 | 0.039g/kg | 10.01±2.40** |
模型对照组 | 10 | 12.82±2.19 | |
正常对照组 | 10 | 8.54±0.84 |
组别 | 动物数(只) | 剂量 | 血糖含量(mmol/L) |
实施例1组 | 10 | 3.80g生药/kg | 10.95±2.33** |
比较例1组 | 10 | 3.80g生药/kg | 11.65±2.09* |
阳性对照组 | 10 | 0.039g/kg | 10.48±0.67*** |
正常对照组 | 10 | 13.72±3.04 |
组别 | 动物数(只) | 剂量 | 血糖含量(mmol/L) |
实施例1组 | 10 | 3.80g生药/kg | 11.13±2.74** |
比较例1组 | 10 | 3.80g生药/kg | 12.99±2.61* |
阳性对照组 | 10 | 0.039g/kg | 10.39±2.14*** |
模型对照组 | 10 | 15.31±2.85 | |
正常对照组 | 10 | 8.23±1.50*** |
Claims (5)
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CN201410854702.6A CN104524359B (zh) | 2014-12-31 | 2014-12-31 | 一种中药组合物、其制备方法及应用 |
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CN201410854702.6A CN104524359B (zh) | 2014-12-31 | 2014-12-31 | 一种中药组合物、其制备方法及应用 |
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CN104524359A CN104524359A (zh) | 2015-04-22 |
CN104524359B true CN104524359B (zh) | 2017-08-25 |
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Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109541068A (zh) * | 2018-12-14 | 2019-03-29 | 吉林省德商药业股份有限公司 | 一种复幼合剂成分检测方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57200312A (en) * | 1981-05-30 | 1982-12-08 | Shinshu Yakuhin Kenkyusho:Kk | Chinese medicine preparation |
JPS625124B2 (zh) * | 1978-09-01 | 1987-02-03 | Maruho Kk | |
CN1240591A (zh) * | 1998-06-30 | 2000-01-12 | 肖树恩 | 一种消渴糖 |
CN1557378A (zh) * | 2004-02-07 | 2004-12-29 | 李炳全 | 一种治疗糖尿病的药物 |
CN101007137A (zh) * | 2007-01-24 | 2007-08-01 | 张光珍 | 芪麦苓口服液及其制备方法 |
CN101224283A (zh) * | 2008-02-01 | 2008-07-23 | 赵燕翼 | 治疗糖尿病的中药组合物及其制备方法 |
CN102225152A (zh) * | 2011-06-23 | 2011-10-26 | 贵州弘康药业有限公司 | 麦味地黄口服制剂的制备方法 |
-
2014
- 2014-12-31 CN CN201410854702.6A patent/CN104524359B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS625124B2 (zh) * | 1978-09-01 | 1987-02-03 | Maruho Kk | |
JPS57200312A (en) * | 1981-05-30 | 1982-12-08 | Shinshu Yakuhin Kenkyusho:Kk | Chinese medicine preparation |
CN1240591A (zh) * | 1998-06-30 | 2000-01-12 | 肖树恩 | 一种消渴糖 |
CN1557378A (zh) * | 2004-02-07 | 2004-12-29 | 李炳全 | 一种治疗糖尿病的药物 |
CN101007137A (zh) * | 2007-01-24 | 2007-08-01 | 张光珍 | 芪麦苓口服液及其制备方法 |
CN101224283A (zh) * | 2008-02-01 | 2008-07-23 | 赵燕翼 | 治疗糖尿病的中药组合物及其制备方法 |
CN102225152A (zh) * | 2011-06-23 | 2011-10-26 | 贵州弘康药业有限公司 | 麦味地黄口服制剂的制备方法 |
Non-Patent Citations (1)
Title |
---|
天冬降糖胶囊对四氧嘧啶小鼠血液生化指标的影响;陈红艳等;《中国中医药信息杂志》;20051115;第12卷(第11期);第22页左栏倒数第24-26行 * |
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