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CN104435471A - Traditional Chinese medicine powder for treating hypertrophic osteoarthropathy - Google Patents

Traditional Chinese medicine powder for treating hypertrophic osteoarthropathy Download PDF

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Publication number
CN104435471A
CN104435471A CN201510000015.2A CN201510000015A CN104435471A CN 104435471 A CN104435471 A CN 104435471A CN 201510000015 A CN201510000015 A CN 201510000015A CN 104435471 A CN104435471 A CN 104435471A
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parts
radix
chinese medicine
medicine powder
traditional chinese
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张来意
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264—Aristolochia (Dutchman's pipe)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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Abstract

The invention provides traditional Chinese medicine powder for treating hypertrophic osteoarthropathy. The traditional Chinese medicine powder for treating hypertrophic osteoarthropathy is prepared by raw materials such as liquorice, astragalus membranaceus, aristolochia mollissima, angelica, pangolin scales, codonopsis pilosula, pyrola, ligusticum wallichii, davallia mariesii, acorus gramineus, radix clematidis, rhizoma atractylodis, rehmannia glutinosa, asarum sieboldii and cuscuta chinensis. The traditional Chinese medicine powder has the effects of eliminating pathogens, dredging collaterals, promoting blood circulation to remove blood stasis, dredging to stop pain and the like, and can effectively treat hypertrophic osteoarthropathy. The cure rate can reach 96% through the traditional Chinese medicine powder for treating hypertrophic osteoarthropathy.

Description

A kind of Chinese medicine powder for the treatment of hyperosteogeny
Technical field
The present invention relates to tcm field, particularly relate to a kind of Chinese medicine powder for the treatment of hyperosteogeny.
Background technology
Bone matrix hyperplasia is also hypertrophy spondylitis, lumbar vertebra bone spur, lumbar retrogression, lumbar vertebra arthritis, and be a kind of skeletal diseases comparatively common and occurred frequently of middle-aged and elderly people, Etiological is relevant with the degeneration of articular cartilage.The middle age prevalence in 40-50 year reaches 50% according to statistics, and the old people of more than 60 years old nearly all in various degree suffer from this disease.Lumbar hyperosteogency patient, when the degeneration of articular cartilage, also may have hyperosteogeny to be formed at cone edge.Clinically show as that sore waist and aching in the waist and the back that hypertrophy pressuring nerve causes, lumbar vertebra are stiff, numbness of lower limbs, pain are neglected indiscreet and negligent heavy, time movable, pain increases the weight of, and takes a favourable turn again after rest more.Not only have a strong impact on the orthobiosis of patient, severe patient also may cause patient's difficulty in walking and even paralyse.Up to now, specific drug be there is no to lumbar hyperosteogency, usually can take the methods such as physical therapy, massage, acupuncture and Chinese and Western patent medicine treatment.
Summary of the invention
Object of the present invention is exactly provide a kind of Chinese medicine powder for the treatment of hyperosteogeny for above-mentioned situation.Object of the present invention realizes by following scheme: a kind of Chinese medicine powder for the treatment of hyperosteogeny, and it is the powder be made up by weight of following bulk drugs: Radix Glycyrrhizae 8-12 part, Radix Astragali 12-18 part, Herba Aristolochiae Mollissimae 12-18 part, Radix Angelicae Sinensis 12-18 part, roasted SQUAMA MANITIS into puffy with sand 8-12 part, Radix Codonopsis 15-25 part, Herba Pyrolae 9-15 part, Rhizoma Chuanxiong 9-15 part, Rhizoma Drynariae 15-25 part, Rhizoma Acori Graminei 8-12 part, Radix Clematidis 9-15 part, Rhizoma Atractylodis 9-15 part, Radix Rehmanniae Preparata 12-18 part, Herba Asari 3-7 part, Semen Cuscutae 9-15 part.
Preferably, the Chinese medicine powder for the treatment of hyperosteogeny that the present invention closely states is the powder be made up by weight of following bulk drugs: 10 parts, Radix Glycyrrhizae, the Radix Astragali 15 parts, Herba Aristolochiae Mollissimae 15 parts, Radix Angelicae Sinensis 15 parts, roasted SQUAMA MANITIS into puffy with sand 10 parts, Radix Codonopsis 20 parts, Herba Pyrolae 12 parts, Rhizoma Chuanxiong 12 parts, Rhizoma Drynariae 20 parts, Rhizoma Acori Graminei 10 parts, Radix Clematidis 12 parts, Rhizoma Atractylodis 12 parts, 15 parts, Radix Rehmanniae Preparata, Herba Asari 5 parts, Semen Cuscutae 12 parts.
Preparation method of the present invention is as follows: medicinal for above-mentioned raw materials frozen drying method is ground into fine powder, and particle diameter is 300-1000 order.
Usage of the present invention and consumption as follows: the present invention is oral medicine, each 10 grams, every day 2 times, within 20 days, is a course for the treatment of.
The present invention has the effects such as eliminating evil dredging collateral, blood circulation promoting and blood stasis dispelling and dredging relieve the pain, and effectively can treat hyperosteogeny.
Be further described below by clinical experiment effect to invention:
Diagnostic criteria
Make a definite diagnosis according to " lumbar vertebra hyperosteogeny diagnosis and treatment standard " typing that hyperosteogeny Professional Committee of Chinese Medical Association formulates, all patients all takes the photograph sheet through lumbar X line or CT sheet is clarified a diagnosis, and gets rid of other bone lesions.Clinical characters is: 1, without in obvious inducement situation, there is waist and back swollenly to rise, stiff, feels pain, miserable, movable dumb, morning rises, sitting pain increases the weight of, and activity symptom a little alleviates sometimes, but overworked symptom increases the weight of again.Sometimes pain is to buttocks and huckle radiation, and extends from thigh lateral shank.2, sign inspection finds that the physiological bending of patient's waist flattens, disappears or circle back of the body deformity, and the spinous process at the limitation of activity of waist, waist and back has percussion pain, and the nervous or tenderness of spinal muscle as bilateral, can occur sciatic irritation sometimes.3, x-ray takes the photograph sheet or CT sheet inspection visible lumbar vertebra physiology lordosis diminishes or disappears, and vertebral rim lip sample changes, narrowing of intervertebral space or asymmetric (beloid), spinal column limitation of activity, and the hyperostosis of cone soleplate is hardened, and edge hyperosteogeny is formed, posterior joint intussusception.4, CY/MRI check result conforms to clinical.
Selector close state diagnostic criteria patient 50 example, wherein man 25 example, female 25 example, 54 years old mean age.
During treatment, the oral powder of the present invention of patient, every day 3 times, each 10 grams, treatment 20 days continuously.
Criterion of therapeutical effect
With reference to State Administration of Traditional Chinese Medicine " disease of tcm Standardization of diagnosis and curative effect ", clinical cure: pain and other clinical condition disappear, and function is normal, and activity is freely.Effective: pain disappears substantially, activity is not limited or slightly feel uncomfortable, and sign recovers original animation substantially.Effective: pain and other clinical symptom reliefs, movable function progress, sign major part can recover original animation.Invalid: treat 20 days, symptom, sign are without improvement.
Through treatment, have 48 examples to reach criterion of cure, cure rate is that 96%, 2 examples reach effective standard.

Claims (2)

1. treat the Chinese medicine powder of hyperosteogeny for one kind, it is characterized in that the powder be made up by weight of following bulk drugs: Radix Glycyrrhizae 8-12 part, Radix Astragali 12-18 part, Herba Aristolochiae Mollissimae 12-18 part, Radix Angelicae Sinensis 12-18 part, roasted SQUAMA MANITIS into puffy with sand 8-12 part, Radix Codonopsis 15-25 part, Herba Pyrolae 9-15 part, Rhizoma Chuanxiong 9-15 part, Rhizoma Drynariae 15-25 part, Rhizoma Acori Graminei 8-12 part, Radix Clematidis 9-15 part, Rhizoma Atractylodis 9-15 part, Radix Rehmanniae Preparata 12-18 part, Herba Asari 3-7 part, Semen Cuscutae 9-15 part, preparation method of the present invention is as follows: medicinal for above-mentioned raw materials frozen drying method is ground into fine powder, and particle diameter is 300-1000 order.
2. Chinese medicine powder according to claim 1, is characterized in that the powder be made up by weight of following bulk drugs: 10 parts, Radix Glycyrrhizae, the Radix Astragali 15 parts, Herba Aristolochiae Mollissimae 15 parts, Radix Angelicae Sinensis 15 parts, roasted SQUAMA MANITIS into puffy with sand 10 parts, Radix Codonopsis 20 parts, Herba Pyrolae 12 parts, Rhizoma Chuanxiong 12 parts, Rhizoma Drynariae 20 parts, Rhizoma Acori Graminei 10 parts, Radix Clematidis 12 parts, Rhizoma Atractylodis 12 parts, 15 parts, Radix Rehmanniae Preparata, Herba Asari 5 parts, Semen Cuscutae 12 parts.
CN201510000015.2A 2015-01-01 2015-01-01 Traditional Chinese medicine powder for treating hypertrophic osteoarthropathy Pending CN104435471A (en)

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CN201510000015.2A CN104435471A (en) 2015-01-01 2015-01-01 Traditional Chinese medicine powder for treating hypertrophic osteoarthropathy

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1310014A (en) * 2001-02-20 2001-08-29 叶庆莲 Lumbago treating Chinese medicine
CN1468608A (en) * 2002-07-19 2004-01-21 张长春 Chinese medicine for treating hyperosteogeny

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1310014A (en) * 2001-02-20 2001-08-29 叶庆莲 Lumbago treating Chinese medicine
CN1468608A (en) * 2002-07-19 2004-01-21 张长春 Chinese medicine for treating hyperosteogeny

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
崔庆奎: "中西医结合治疗腰椎骨质增生的临床疗效研究", 《中医临床研究》 *

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Application publication date: 20150325