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CN104434731A - Nutritional nourishing hand cream and preparation method thereof - Google Patents

Nutritional nourishing hand cream and preparation method thereof Download PDF

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CN104434731A
CN104434731A CN201410658015.7A CN201410658015A CN104434731A CN 104434731 A CN104434731 A CN 104434731A CN 201410658015 A CN201410658015 A CN 201410658015A CN 104434731 A CN104434731 A CN 104434731A
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CN104434731B (en
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孙淑萍
刘侠
张毓婷
钱张超
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Shanghai Meifute Biotechnology Co ltd
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Wannan Medical College
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Abstract

本发明公开了一种营养滋润型护手霜及其制备方法,该护手霜中含有以下物质:乳木果油、马油、小麦胚芽油、玫瑰浸泡油、雪莲花浸泡油、勿忘我浸泡油、万用自乳化复合型乳化剂AC-402、25%三乙醇胺、白芨提取液、绿茶提取液、猕猴桃榨取液、火棘果榨取液、1,2-丙二醇、生物多糖胶、20%尿素溶液、Liponic EG-1、海藻糖、烟酰胺、蜂蜜、维生素E、海藻酸钠、羟丙基甲基纤维素、1%乙二胺四乙酸二钠溶液、10%柠檬酸溶液、5%尼泊金乙酯醇溶液、蒸馏水、香精。跟现有技术相比,本发明产品为手部肌肤带来丰富营养,能深层滋润来修护干燥粗糙的双手,调节水油平衡,软化老废角质,抚平细纹,为双手补充水分,增加保湿美白的功效。The invention discloses a nourishing and moisturizing hand cream and a preparation method thereof. The hand cream contains the following substances: shea butter, horse oil, wheat germ oil, rose soaking oil, snow lotus soaking oil, forget-me-not soaking oil Oil, universal self-emulsifying compound emulsifier AC-402, 25% triethanolamine, bletilla striata extract, green tea extract, kiwifruit extract, fireacantha extract, 1,2-propylene glycol, biopolysaccharide gum, 20% urea solution, Liponic EG-1, trehalose, niacinamide, honey, vitamin E, sodium alginate, hydroxypropyl methylcellulose, 1% disodium edetate solution, 10% citric acid solution, 5% nicotinic acid solution Parkin Ethyl Ester Alcohol Solution, Distilled Water, Essence. Compared with the prior art, the product of the present invention brings rich nutrition to the skin of hands, can deeply moisturize dry and rough hands, adjust the balance of water and oil, soften old dead skin cells, smooth fine lines, and replenish moisture for hands. Increase the effect of moisturizing and whitening.

Description

一种营养滋润型护手霜及其制备方法Nutritious and moisturizing hand cream and preparation method thereof

技术领域technical field

本发明属于护肤品领域,具体涉及一种营养滋润型护手霜及其制备方法。The invention belongs to the field of skin care products, and in particular relates to a nourishing and moisturizing hand cream and a preparation method thereof.

背景技术Background technique

因为长期遭受阳光、污染、寒冷等外界刺激,导致手部肌肤老化、干燥问题已呈现年轻化、普遍化的趋势,解决手部问题是生活质量提升的体现。众所周知,手是女人的第二张脸,可见手部肌肤的保养是极其重要的,拥有一双健康洁白玉手是每位爱美人士的孜孜追求。然而,我们常常要忍受天气、化学品、劳动给手带来的伤害,却买不到安全有效的护手霜,使人们受到手部问题的困扰,如干燥,起皮,冻疮,皮肤老化、发黄等,这些问题使青春的美丽潇洒打大折扣,也是给我们的生活带来不少困扰。Due to long-term exposure to external stimuli such as sunlight, pollution, and cold, hand skin aging and dryness have become younger and more common. Solving hand problems is a manifestation of improving the quality of life. As we all know, hands are the second face of a woman. It can be seen that the maintenance of hand skin is extremely important. Having a pair of healthy and white hands is the pursuit of every beauty lover. However, we often have to endure the damage to our hands from weather, chemicals, and labor, but we cannot buy safe and effective hand creams, so that people are troubled by hand problems, such as dryness, peeling, frostbite, skin aging, Yellowing, etc. These problems greatly reduce the beauty of youth, and also bring a lot of trouble to our lives.

花果类富有的植物多糖、维生素及其活性成分皆具有特殊的功效,是天然的功能性化妆品的最好原料,正确选用天然植物,在护手霜中添加植物精华,可建立锁水屏障机制来对应外在环境刺激,避免水分流失。每种植物所特有的活性成分能为手部肌肤提供多种珍贵营养素,减少细纹产生,嫩白肌肤,提升肌肤的色泽和明亮感,给予手部肌肤深层护理。利用先进科技,萃取天然花果中的植物精华成分加入护手霜中,能全面改善手部肌肤,重塑丰盈柔嫩的纤纤玉手,无论对于时尚男女还是中老年人而言,使用含天然花果精华提取物的滋润保湿护手霜都是一种既科学有效又方便快捷的护肤方法。Flowers and fruits rich in plant polysaccharides, vitamins and their active ingredients all have special effects and are the best raw materials for natural functional cosmetics. Proper selection of natural plants and adding plant essences to hand cream can establish a water-locking barrier mechanism To respond to external environmental stimuli and avoid water loss. The unique active ingredients of each plant can provide a variety of precious nutrients to the skin of the hands, reduce the appearance of fine lines, whiten the skin, enhance the color and brightness of the skin, and give the skin of the hands a deep care. Utilizing advanced technology, extracting plant essences from natural flowers and fruits and adding them to hand cream can comprehensively improve the skin of hands and reshape plump and soft slender hands. No matter for fashionable men and women or middle-aged and elderly people, using natural flowers and fruits Moisturizing hand cream with essence extracts is a scientific, effective, convenient and quick skin care method.

发明内容Contents of the invention

本发明的目的在于提供一种营养滋润型护手霜,含天然花果植物精华。The object of the present invention is to provide a nourishing and moisturizing hand cream containing natural flower and fruit plant essence.

本发明还有一个目的在于提供一种营养滋润型护手霜的制备方法。Another object of the present invention is to provide a method for preparing a nourishing and moisturizing hand cream.

一种营养滋润型护手霜,以重量份数计其原料组分及含量为:A kind of nourishing and moisturizing hand cream, its raw material components and contents are as follows in parts by weight:

所述的白芨提取液是通过以下方法制备:The bletilla striata extract is prepared by the following method:

称取白芨适量,浸泡0.15-1h,加热至90-100℃,煎煮提取3次,第1次加6-12倍量水,提取0.5-2h,第2次加4-10倍量水,提取0.5-1.5h,第3次加3-8倍量水,提取0.5-1.5h,每次滤过,合并滤液,滤液的体积浓缩至白芨重量的3-6倍g/ml,过滤,取滤液,即得。Weigh an appropriate amount of Bletilla striata, soak for 0.15-1h, heat to 90-100°C, decoct and extract 3 times, add 6-12 times the amount of water for the first time, extract for 0.5-2h, add 4-10 times the amount of water for the second time, Extract for 0.5-1.5h, add 3-8 times the amount of water for the third time, extract for 0.5-1.5h, filter each time, combine the filtrate, concentrate the volume of the filtrate to 3-6 times g/ml of the weight of Bletilla striata, filter, and take Filtrate, that is.

所述的绿茶提取液通过以下方法制备:Described green tea extract is prepared by the following method:

称取绿茶适量,浸泡0.15-0.8h,于90-100℃加热煎煮提取3次,第1次加6-12倍量水,提取0.5-2h,第2次加4-10倍量水,提取0.5-1.5h,第3次加3-8倍量水,提取0.5-1.5h,每次滤过,合并滤液,滤液的体积浓缩至绿茶重量的3-6倍g/ml,过滤,取滤液,即得。Weigh an appropriate amount of green tea, soak for 0.15-0.8h, heat and decoct at 90-100°C for extraction 3 times, add 6-12 times the amount of water for the first time, extract for 0.5-2h, add 4-10 times the amount of water for the second time, Extract for 0.5-1.5h, add 3-8 times the amount of water for the third time, extract for 0.5-1.5h, filter each time, combine the filtrate, concentrate the volume of the filtrate to 3-6 times the weight of green tea g/ml, filter, and take Filtrate, that is.

所述的猕猴桃榨取液通过以下方法制备:Described kiwi fruit extracting liquid is prepared by the following method:

称取新鲜猕猴桃,去皮,切块,称取一定量,放入到榨汁机中,并加入8-12倍g/ml的蒸馏水,所得猕猴桃汁用双层纱布滤过3-6次,过滤,取滤液,即得。Weigh fresh kiwi fruit, peel, cut into pieces, weigh a certain amount, put it into a juice extractor, and add 8-12 times g/ml distilled water, and filter the obtained kiwi fruit juice with double-layer gauze for 3-6 times, Filter and take the filtrate, that is, too.

所述的火棘果榨取液通过以下方法制备:Described fire-acantha extracting liquid is prepared by the following method:

称取新鲜火棘果一定量,放入到榨汁机中,并加入8-12倍g/ml的蒸馏水,所得火棘果汁用双层纱布滤过3-6次,过滤,取滤液,即得。Weigh a certain amount of fresh Pyracantha fruit, put it into a juice extractor, and add 8-12 times g/ml distilled water, filter the Pyracantha fruit juice with double-layer gauze for 3-6 times, filter, and take the filtrate, namely have to.

所述的玫瑰浸泡油通过以下方法制备:Described rose steeping oil is prepared by the following method:

称取干玫瑰适量,浸泡于10-18倍g/ml玉米油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of dried rose, soak in 10-18 times g/ml corn oil, soak for 12-24h, ultrasonically extract at 30-60°C for 5-6h, filter, and take the filtrate to obtain the product.

所述的雪莲花浸泡油通过以下方法制备:Described snow lotus soaking oil is prepared by the following method:

称取干雪莲花适量,浸泡于10-18g/ml倍玉米油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of dried snow lotus, soak in 10-18g/ml corn oil, soak for 12-24h, ultrasonically extract at 30-60°C for 5-6h, filter, and take the filtrate to obtain the product.

所述的勿忘我浸泡油通过以下方法制备:The forget-me-not soaking oil is prepared by the following method:

称取勿忘我适量,浸泡于10-18倍油茶籽油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of forget-me-not, soak in 10-18 times the camellia seed oil, soak for 12-24h, ultrasonically extract at 30-60°C for 5-6h, filter, and take the filtrate to obtain the product.

所述的香精为玫瑰香精、水蜜桃香精、菠萝香精、柠檬香精、青瓜香精、茉莉香精、桂花香精中的一种。The essence is one of rose essence, peach essence, pineapple essence, lemon essence, cucumber essence, jasmine essence and osmanthus essence.

本发明提供的一种营养滋润型护手霜的制备方法,包括以下步骤:A kind of preparation method of nourishing moisturizing type hand cream provided by the invention comprises the following steps:

a)称取海藻酸钠0.01-0.5份,溶于1-10份蒸馏水中,加热至60-80℃,边加热边搅拌,混合均匀后,静置让其充分溶胀,得海藻酸钠溶液;a) Weigh 0.01-0.5 parts of sodium alginate, dissolve in 1-10 parts of distilled water, heat to 60-80°C, stir while heating, mix evenly, let stand to let it fully swell, and obtain sodium alginate solution;

b)称取羟丙基甲基纤维素0.01-0.5份,分散于5-12份蒸馏水中,迅速搅拌至均匀,静置,自然溶胀5-7h,待用;b) Weigh 0.01-0.5 parts of hydroxypropyl methylcellulose, disperse in 5-12 parts of distilled water, stir rapidly until uniform, let stand, and swell naturally for 5-7 hours, and set aside;

c)称取乳木果油0.5-5.0份、马油0.2-5.0份、小麦胚芽油1.0-5.0份、玫瑰浸泡油1.0-5.0份、雪莲花浸泡油1.0-5.0份、勿忘我浸泡油1.0-5.0份、万用自乳化复合型乳化剂AC-4021.0-5.0份置于烧杯中于水浴锅上保持温度60-90℃水浴加热熔融,作为油相;c) Weigh 0.5-5.0 parts of shea butter, 0.2-5.0 parts of horse oil, 1.0-5.0 parts of wheat germ oil, 1.0-5.0 parts of rose soaking oil, 1.0-5.0 parts of snow lotus soaking oil, and 1.0 parts of forget-me-not soaking oil -5.0 parts, universal self-emulsifying compound emulsifier AC-402 1.0-5.0 parts are placed in a beaker, heated and melted in a water bath at a temperature of 60-90 ° C, as the oil phase;

d)称取蒸馏水4.0-50.0份、25%三乙醇胺溶液1.0-5.0份、置于60-90℃水浴加热,得到水相;d) Weighing 4.0-50.0 parts of distilled water and 1.0-5.0 parts of 25% triethanolamine solution, heating in a water bath at 60-90°C to obtain an aqueous phase;

e)称取Liponic EG-11.0-5.0份、1-2丙二醇1.0-5.0份、生物多糖胶2.0份-5.0份、步骤a)制备的海藻酸钠溶液、步骤b)制备的羟丙基甲基纤维素溶液,加热升温至80-90℃,搅拌均匀,得到增稠剂;e) Weigh 11.0-5.0 parts of Liponic EG-1, 1.0-5.0 parts of 1-2 propylene glycol, 2.0-5.0 parts of biopolysaccharide gum, the sodium alginate solution prepared in step a), and the hydroxypropylmethyl prepared in step b). The cellulose solution is heated to 80-90°C, stirred evenly to obtain a thickener;

f)待油相完全熔融,将水相倒入油相中,边加边向同一方向搅拌,至呈均匀乳白色膏状,即得基质,将基质冷至室温;f) After the oil phase is completely melted, pour the water phase into the oil phase, and stir in the same direction while adding, until it becomes a uniform milky white paste, that is, the matrix is obtained, and the matrix is cooled to room temperature;

g)称取蜂蜜0.1-2.0份、海藻糖0.5-5.0份、烟酰胺0.01-1.0份、维生素E 0.1-1.0份、20%尿素溶液1.0-5.0份、白芨提取液0.1-3.0份、绿茶提取液0.1-3.0份、火棘果榨取液0.1-3.0份、猕猴桃榨取液0.1-3.0份,搅拌混合均匀,加入冷却后的基质中,得到乳霜膏体;g) Weigh 0.1-2.0 parts of honey, 0.5-5.0 parts of trehalose, 0.01-1.0 parts of nicotinamide, 0.1-1.0 parts of vitamin E, 1.0-5.0 parts of 20% urea solution, 0.1-3.0 parts of Bletilla striata extract, green tea extract 0.1-3.0 parts of liquid, 0.1-3.0 parts of Pyracantha fruit extract, 0.1-3.0 parts of kiwifruit extract, stir and mix evenly, add to the cooled base to obtain cream paste;

h)向步骤g)所得的乳霜膏体加入步骤e)所制的增稠剂,搅拌10-15min,混合均匀,再加入10%柠檬酸溶液0.1-5.0份,调节pH在6-7之间;h) Add the thickener prepared in step e) to the cream paste obtained in step g), stir for 10-15 minutes, mix well, then add 0.1-5.0 parts of 10% citric acid solution, and adjust the pH between 6-7 between;

i)最后加入1%乙二胺四乙酸二钠溶液0.01-5.0份、5%尼泊金乙酯醇溶液0.01-5.0份,其中乙醇浓度为75%,1%香精0.01-0.05份,搅拌均匀,即得含天然花果植物精华的营养滋润型护手霜。i) Finally, add 0.01-5.0 parts of 1% disodium edetate solution, 0.01-5.0 parts of 5% ethylparaben alcohol solution, wherein the ethanol concentration is 75%, 0.01-0.05 parts of 1% essence, and stir well , that is, a nourishing and moisturizing hand cream containing natural flower and fruit plant extracts.

本发明中的各种成分如下:Various compositions among the present invention are as follows:

乳木果油被称为“液体黄金”,是一种纯天然绿色植物源固体油脂,极易于人体吸收,能促进表皮细胞再生,深层滋润,防止干燥开裂,在肌肤表层形成保护膜,保湿、防晒、防护功效显著。它含有的植物固醇对于受伤的皮肤兼具抗炎、抗敏的作用,含有的天然防晒成分-肉桂酸有抑制形成黑色酪氨酸酶的作用,对紫外线有一定的隔绝作用,能使褐斑变浅、甚至消失。乳木果油因其超强的抗氧化效果,温和无刺激,可保持肌肤自然弹性,是用于保护双手、滋润肌肤的理想原料,适用于敏感性肌肤在内的各类婴儿、儿童肌肤、成人使用。Shea butter, known as "liquid gold", is a pure natural green plant-sourced solid oil, which is easily absorbed by the human body, can promote epidermal cell regeneration, deeply moisturize, prevent dryness and cracking, form a protective film on the skin surface, and moisturize , sun protection, protection effect is remarkable. The phytosterols it contains have anti-inflammatory and anti-allergic effects on the injured skin. The natural sunscreen ingredient-cinnamic acid contained in it can inhibit the formation of black tyrosinase, have a certain effect on the isolation of ultraviolet rays, and can make brown Spots become lighter or even disappear. Because of its strong anti-oxidation effect, shea butter is mild and non-irritating, and can maintain the natural elasticity of the skin. It is an ideal raw material for protecting hands and moisturizing the skin. It is suitable for all kinds of babies, children's skin, sensitive skin, Adult use.

马油的主要组分为油酸、亚油酸和棕榈酸,其中油酸和亚油酸总含量为50%。马油里含有的营养素(维他命E和亚麻酸)能恢复肌体健康和使肌肤柔嫩,并且可加强对疾病的免疫力和抵抗力。马油少量的“饱和脂肪酸”在皮肤表面形成一层保护膜,其大量的不饱和脂肪酸被皮肤吸收,参与人体皮肤组织的代谢功能,对皮肤受损细胞的修复起到了非常重要的作用。The main components of horse oil are oleic acid, linoleic acid and palmitic acid, wherein the total content of oleic acid and linoleic acid is 50%. The nutrients contained in horse oil (vitamin E and linolenic acid) can restore the health of the body and make the skin soft, and can strengthen the immunity and resistance to diseases. A small amount of "saturated fatty acid" in horse oil forms a protective film on the skin surface, and a large amount of unsaturated fatty acid is absorbed by the skin, participates in the metabolic function of human skin tissue, and plays a very important role in the repair of damaged skin cells.

玫瑰花含挥发油(玫瑰油)、槲皮苷、苦味质、脂肪、鞣质、多种维生素、葡萄糖、果糖、柠檬糖等对人体健康有益的成分,具有抗衰老、美白的功效,能有效地清除自由基,消除色素沉着,令人唤发青春活力,长期使用能使肌肤滋润而富有光泽,长期服用,美容效果甚佳。玫瑰花提取油具有保湿、滋养的功效,使干燥敏感的肌肤及时恢复水润柔嫩;具有收敛、抗菌和镇静舒缓的作用,紧致毛孔、抑制过多油脂分泌,使肌肤细腻清新,不泛油光;玫瑰香气能舒缓紧致情绪,进而放松心情,给人安心与幸福感,消除压力,进一步提升美肌效果。Roses contain volatile oil (rose oil), quercetin, bitter quality, fat, tannins, multivitamins, glucose, fructose, lemon sugar and other ingredients that are beneficial to human health. Scavenging free radicals, eliminating pigmentation, and arousing youthful vitality, long-term use can make the skin moist and lustrous, long-term use, the beauty effect is very good. Rose extract oil has moisturizing and nourishing effects, making dry and sensitive skin instantly moist and tender; it has astringent, antibacterial, calming and soothing effects, tightens pores, inhibits excessive oil secretion, and makes skin delicate and fresh without oily shine ;The aroma of roses can soothe and tighten emotions, and then relax the mood, giving people peace of mind and happiness, eliminating stress, and further enhancing the skin beautification effect.

勿忘我具有清热解毒,清心明目,滋阴补肾,美容养颜,养血调经之功效,并能促经机体新陈代谢,延缓细胞衰老,提高免疫能力。含维他命C,美容增白,避免皱纹及黑斑的产生,特别是对雀斑、粉刺有一定的消除作用。Forget-me-not has the functions of clearing heat and detoxification, clearing heart and improving eyesight, nourishing yin and kidney, beautifying skin, nourishing blood and regulating menstruation. It can also promote the metabolism of the body, delay cell aging and improve immunity. Contains vitamin C, beautifies and whitens, avoids wrinkles and dark spots, especially has a certain effect on eliminating freckles and acne.

雪莲花是理想的天然抗衰老剂,自古以来就是治疗皮肤病的良药。其含有雪莲内脂、雪莲多糖、氨基酸、维生素、糖分、矿物质、甾醇类化合物、生物酶等活性物质。其防晒系数高达22SPF,远高于15SPF的国内超强度紫外线辐射。因此,可有效地保护皮肤免受紫外线侵害,并对体内毒素所致肝脏及血清中过氧化脂质的升高具有明显的抑制作用。雪莲具抗炎、组织修复和抗超氧化物自由基的功效,对防御由生理或非生理因素(如疾病)诱发自由基长期慢性进行性损伤有着积极意义。这种功效,在内服时表现为保健和增强免疫功能,外用时可达到美容、祛斑、延缓皮肤衰老的目的。雪莲磨成粉浸泡液能营养皮肤,并能抑制表皮癣菌、星形努卡菌等皮肤真菌,有较好的治疗作用,还可以遮挡紫外线。雪莲花可加速皮肤新陈代谢,平衡内分泌,自然除火祛斑,减少皱纹,使皮肤保持光泽、丰满、对面部雀斑、肝斑等有良好的疗效。雪莲的这些优良特性用于护肤、护发,对皮肤有滋润、灭菌、消炎、生肌、防晒、软化、平滑和净白作用。Snow lotus is an ideal natural anti-aging agent and has been a good medicine for skin diseases since ancient times. It contains yacon lactone, yacon polysaccharides, amino acids, vitamins, sugars, minerals, sterol compounds, biological enzymes and other active substances. Its sun protection factor is as high as 22SPF, which is much higher than the domestic super-intensity ultraviolet radiation of 15SPF. Therefore, it can effectively protect the skin from ultraviolet rays, and has a significant inhibitory effect on the increase of lipid peroxide in the liver and serum caused by toxins in the body. Snow lotus has the functions of anti-inflammation, tissue repair and anti-superoxide free radicals, and it has positive significance in the defense of long-term chronic progressive damage of free radicals induced by physiological or non-physiological factors (such as diseases). This effect, when taken internally, manifests as health care and enhancing immune function, and when used externally, it can achieve the purposes of beauty treatment, freckle removal, and delaying skin aging. Snow lotus ground into powder and soaking liquid can nourish the skin, and can inhibit skin fungi such as Epidermophyton and Nocardia asteroides. It has a good therapeutic effect and can also block ultraviolet rays. Snow lotus can accelerate skin metabolism, balance endocrine, naturally remove fire and freckles, reduce wrinkles, keep skin shiny and plump, and has a good effect on facial freckles and liver spots. These excellent properties of snow lotus are used for skin care and hair care, and have moisturizing, sterilizing, anti-inflammatory, muscle-growing, sun-proof, softening, smoothing and whitening effects on the skin.

生物多糖胶是一种1%的线性聚多糖粘性溶液,同时完美地拥有良好的感官优势及保湿功效,是最好的“活性赋形剂”。糖的“吸水”能力加强了其保湿功效。从长时间来看,生物多糖胶可为皮肤提供更强的水合作用。Biopolysaccharide gum is a 1% linear polysaccharide viscous solution, which perfectly has good sensory advantages and moisturizing effect, and is the best "active excipient". Sugar's ability to "absorb water" enhances its moisturizing properties. Bio-polysaccharide gum provides enhanced hydration to the skin over time.

维生素E为一重要的抗氧化剂。维生素E能稳定细胞膜的蛋白活性结构,促进肌肉的正常发育及保持肌肤的弹性,令肌肤和身体保持活力。维生素E具有抗衰老的功效,进入皮肤细胞能更直接帮助肌肤对抗自由基、紫外线和污染物的侵害,防止肌肤因一些慢性或隐性的伤害而失去弹性直至老化,同时可消除脂褐素在细胞中的沉积,改善细胞的正常功能,减慢组织细胞的衰老过程。Vitamin E is an important antioxidant. Vitamin E can stabilize the active protein structure of the cell membrane, promote the normal development of muscles and maintain the elasticity of the skin, keeping the skin and body alive. Vitamin E has an anti-aging effect. When it enters the skin cells, it can directly help the skin resist free radicals, ultraviolet rays and pollutants, prevent the skin from losing its elasticity and aging due to some chronic or hidden damage, and at the same time eliminate lipofuscin in the skin. Deposition in cells improves the normal function of cells and slows down the aging process of tissue cells.

绿茶有助于延缓衰老,预防和治疗辐射伤害。绿茶中有助于美容护肤的茶多酚具有很强的抗氧化性和生理活性,是人体自由基的清除剂,有阻断脂质过氧化反应,清除活性酶的作用。茶多酚及其氧化产物具有吸收放射性物质锶90和钴60毒害的能力。茶多酚是水溶性物质,用它洗脸能清除面部的油腻,收敛毛孔,具有消毒、灭菌、抗皮肤老化,减少日光中的紫外线辐射对皮肤的损伤等功效。Green tea helps to delay aging, prevent and treat radiation damage. Tea polyphenols in green tea, which are helpful for beauty and skin care, have strong antioxidant and physiological activities. They are scavengers of free radicals in the human body, and they can block lipid peroxidation and scavenge active enzymes. Tea polyphenols and their oxidation products have the ability to absorb the poison of radioactive substances strontium 90 and cobalt 60. Tea polyphenols are water-soluble substances. Washing the face with it can remove the greasy face, tighten pores, have the functions of disinfection, sterilization, anti-aging skin, and reduce the damage of ultraviolet radiation in the sun to the skin.

猕猴桃有生津解热、滋补强身之功效。其含有硫醇蛋白酶的水解酶和超氧化物歧化酶,具有养颜、提高免疫力、抗衰老、软化血管、抗肿、消炎功能和乌发美容、娇嫩皮肤的作用。猕猴桃中含有丰富的维生素A、维生素C和维生素E,而且具有抗氧化作用,能有效增白皮肤,消除雀斑和暗疮,增强皮肤的抗衰老能力,强化免疫系统,促进伤口愈合,对痘痘和痘印都有相当疗效。Kiwi fruit has the effects of promoting body fluid and relieving heat, nourishing and strengthening the body. It contains hydrolase of thiol protease and superoxide dismutase, which has the functions of beautifying, improving immunity, anti-aging, softening blood vessels, anti-tumor, anti-inflammation, black hair, beautifying and delicate skin. Kiwi fruit is rich in vitamin A, vitamin C and vitamin E, and has antioxidant effect, which can effectively whiten the skin, eliminate freckles and acne, enhance the skin's anti-aging ability, strengthen the immune system, promote wound healing, and treat acne and acne. Acne marks are quite effective.

火棘果实含有丰富的有机酸、蛋白质、氨基酸、维生素和多种矿质元素。火棘果中含有生物增白物质,能有效地抑制人体内各种色素酶的活力,使皮肤不产生色素。一些红果产区的妇女都用红果汁液敷面据说增白效果很好,其提取液被广泛用于化妆品中。Pyracantha fruit is rich in organic acids, proteins, amino acids, vitamins and various mineral elements. Pyracantha contains biological whitening substances, which can effectively inhibit the activity of various pigment enzymes in the human body, so that the skin does not produce pigment. Women in some red fruit producing areas use red fruit juice to apply to their faces. It is said that the whitening effect is very good, and its extract is widely used in cosmetics.

白芨有收敛止血,消肿生肌,促进上皮细胞修复,直接参与受损组织和细胞的修复和代谢过程,因此具有促进伤口愈合、抗衰老、抗皱、保湿的功效。白芨葡苷聚糖应用于化妆品行业中的上皮细胞修复和祛皱、抗衰老领域。β-葡聚糖通常会引起巨噬细胞活化,而巨噬细胞活化会引起一连串的反应,首先会引起纤维原细胞的活化,从而产生表皮细胞生长因子(ECGF)和血管生成因子(AF)对抗衰老起皱的皮肤。ECGF会促进胶原蛋白和弹性蛋白的生成,从而改善皮肤外观,消除皱纹。Bletilla striata has the functions of astringent and hemostasis, detumescence and muscle growth, promotion of epithelial cell repair, and directly participates in the repair and metabolic process of damaged tissues and cells, so it has the effects of promoting wound healing, anti-aging, anti-wrinkle, and moisturizing. Bletilla striata glucoside is used in the fields of epithelial cell repair, wrinkle removal and anti-aging in the cosmetic industry. β-glucan usually induces the activation of macrophages, and the activation of macrophages will cause a series of reactions, first of all, it will cause the activation of fibroblasts, which will produce epidermal growth factor (ECGF) and angiogenic factor (AF) against Aging wrinkled skin. ECGF boosts collagen and elastin production, which improves skin appearance and reduces wrinkles.

海藻酸钠在化妆品中起良好的增稠作用,可以改善皮肤的保湿性,是化妆品中常见的增稠剂和保湿剂。Sodium alginate has a good thickening effect in cosmetics and can improve skin moisture retention. It is a common thickener and moisturizer in cosmetics.

本护手霜处方中添加了大量的天然花果植物提取成分。一方面通过深层滋润来修护干燥粗糙的双手、调节水油平衡,从而抑制色斑皱纹、防止冻伤、冻疮和干燥开裂的产生。本处方中的众多成分具有全面的营养素和抗氧化成分,如紫草、火棘果、白芨等含有微量元素硒、锰、单不饱和脂肪酸,维生素A、C、E。白芨胶可参与受损组织或细胞的修复和代谢过程,促进上皮细胞修复,消疮祛斑。紫草可以对冻伤、冻疮均有比较好的疗效。再如乳木果油、油茶籽油、小麦胚芽油等天然油脂能深层滋润手部肌肤,抚平细纹,为手部肌肤带来丰富营养,乳木果油与人体皮脂分泌油脂的各项指标最为接近,蕴含丰富的非皂化成分,极易于人体吸收,不仅能防止干燥开裂,还能进一步恢复并保持肌肤的自然弹性,具有较好的深层滋润功效,还兼具抗炎、抗敏和防紫外线的作用,特添加维生素E和尿素有效防止双手因干燥造成的起皮、开裂。The prescription of this hand cream has added a lot of natural flower and fruit plant extracts. On the one hand, it repairs dry and rough hands through deep moisturizing, and adjusts the balance of water and oil, thereby inhibiting pigmentation and wrinkles, preventing frostbite, frostbite and dry cracking. Many ingredients in this prescription have comprehensive nutrients and antioxidant ingredients, such as comfrey, fireacantha, bletilla striata, etc. contain trace elements selenium, manganese, monounsaturated fatty acids, vitamins A, C, and E. Bletilla striata glue can participate in the repair and metabolic process of damaged tissues or cells, promote the repair of epithelial cells, and eliminate sores and freckles. Comfrey can have a better effect on frostbite and frostbite. Another example is shea butter, camellia seed oil, wheat germ oil and other natural oils that can deeply moisturize the skin of the hands, smooth fine lines, and bring rich nutrition to the skin of the hands. The index is the closest. It contains rich non-saponifiable ingredients, which are easily absorbed by the human body. It can not only prevent dryness and cracking, but also further restore and maintain the natural elasticity of the skin. It has good deep moisturizing effect, and is also anti-inflammatory and anti-allergic. And anti-ultraviolet effect, specially added vitamin E and urea to effectively prevent hands from peeling and cracking caused by dryness.

另一方面又通过美白保湿来补充充足营养,美化手部肌肤,使肤色细腻、有光泽、嫩白、有弹性。如玫瑰、雪莲花、勿忘我、猕猴桃、绿茶中富含的植物粘液、矿物质、多糖、有机酸、维生素、抗氧化成分等,可有效地为双手补充水分,舒缓紧绷、干燥的皮肤,软化老废角质,在滋润肌肤的同时,增加保湿美白的功效。On the other hand, it supplements sufficient nutrition through whitening and moisturizing, beautifies the skin of the hands, and makes the complexion delicate, shiny, white and elastic. Such as rose, snow lotus, forget-me-not, kiwi fruit, and green tea rich in plant mucus, minerals, polysaccharides, organic acids, vitamins, antioxidant ingredients, etc., which can effectively replenish moisture for hands and relieve tight and dry skin. Soften the old dead skin cells, while moisturizing the skin, increase the moisturizing and whitening effect.

跟现有技术相比,本护手霜质地软滑,气温芬芳,细腻均一,能深层滋润手部肌肤,柔嫩粗糙肌肤,加速伤口修复,调节皮肤免疫功能,增强皮肤抵御外界刺激,防止冻伤、冻疮,改善皮肤血液循环,促进新陈代谢,使皮肤充满弹性、柔软并拥有持久保湿力和光滑感,可有效的帮助解决手部干涩紧绷不适的感觉,有效抚平各种问题带来的伤害,用后立即觉得舒适滋润。Compared with the existing technology, this hand cream is soft and slippery in texture, fragrant in temperature, fine and uniform, can deeply moisturize the skin of hands, soften and rough skin, accelerate wound repair, regulate skin immune function, enhance skin resistance to external stimuli, prevent frostbite, Frostbite, improve skin blood circulation, promote metabolism, make the skin full of elasticity, softness and long-lasting moisturizing power and smoothness, which can effectively help solve the feeling of dryness, tightness and discomfort of hands, and effectively heal the injuries caused by various problems. Feel comfortable and moisturised immediately after use.

具体实施方式Detailed ways

下面结合实施例对本发明做进一步的描述。The present invention will be further described below in conjunction with the examples.

本发明的乳木果油、白芨、绿茶、猕猴桃为市售。Shea butter, bletilla striata, green tea and kiwi fruit of the present invention are commercially available.

实施例1Example 1

1.1白芨提取物的制备:1.1 Preparation of Bletilla striata extract:

称取白芨50g,浸泡1h,加热至100℃,煎煮提取3次,第1次加12倍量水,提取2h,第2次加10倍量水,提取1.5h,第3次加8倍量水,提取1h,每次滤过,合并滤液,滤液的体积浓缩至白芨重量的6倍g/ml,过滤,取滤液,即得。Weigh 50g of Bletilla striata, soak for 1 hour, heat to 100°C, decoct and extract 3 times, add 12 times the amount of water for the first time, extract for 2 hours, add 10 times the amount of water for the second time, extract for 1.5 hours, and add 8 times the amount for the third time Measure water, extract for 1 hour, filter each time, combine the filtrates, concentrate the volume of the filtrates to 6 times the weight of Bletilla striata in g/ml, filter, and take the filtrates to obtain the product.

1.2绿茶提取液的制备:1.2 Preparation of green tea extract:

称取绿茶20g,浸泡0.8h,于100℃加热煎煮提取3次,第1次加12倍量水,提取2h,第2次加10倍量水,提取1.5h,第3次加8倍量水,提取1h,每次滤过,合并滤液,滤液的体积浓缩至绿茶重量的6倍g/ml,过滤,取滤液,即得。Weigh 20g of green tea, soak for 0.8h, heat and decoct at 100°C for 3 times, add 12 times the amount of water for the first time, extract for 2 hours, add 10 times the amount of water for the second time, extract for 1.5 hours, and add 8 times for the third time Measure water, extract for 1 hour, filter each time, combine the filtrates, concentrate the volume of the filtrates to 6 times the weight of green tea g/ml, filter, and take the filtrates to obtain the product.

1.3猕猴桃榨取液的制备:1.3 Preparation of kiwi fruit extract:

称取新鲜猕猴桃,去皮,切块,称取30g,放入到榨汁机中,并加入12倍的蒸馏水,所得猕猴桃汁用双层纱布滤过5次,过滤,取滤液,即得。Weigh fresh kiwi fruit, peel, cut into pieces, weigh 30g, put it into a juice extractor, and add 12 times of distilled water, filter the obtained kiwi fruit juice with double-layer gauze for 5 times, filter, and take the filtrate.

1.4火棘果榨取液的制备:1.4 Preparation of Pyracantha fruit extract:

称取新鲜火棘果30g,放入到榨汁机中,并加入12倍的蒸馏水,所得火棘果汁用双层纱布滤过6次,过滤,取滤液,即得。Weigh 30g of fresh Pyracantha fruit, put it into a juice extractor, add 12 times of distilled water, filter the obtained Pyracantha japonicus juice with double-layer gauze for 6 times, filter, and take the filtrate to obtain the product.

1.5玫瑰浸泡油取物通过以下方法制备:1.5 The rose soaked oil extract is prepared by the following method:

称取干玫瑰30g,浸泡于18倍g/ml玉米油中,浸泡15h,于40℃超声提取5h,过滤,取滤液,即得。Weigh 30g of dried rose, soak in 18 times g/ml corn oil, soak for 15h, ultrasonically extract at 40°C for 5h, filter, and take the filtrate to obtain the product.

1.6所述的雪莲花浸泡油通过以下方法制备:The snow lotus soaking oil described in 1.6 is prepared by the following method:

称取干雪莲花30g,浸泡于16倍g/ml玉米油中,浸泡15h,于50℃超声提取6h,过滤,取滤液,即得。Weigh 30g of dried snow lotus, soak in 16 times g/ml corn oil, soak for 15h, ultrasonically extract at 50°C for 6h, filter, and take the filtrate to obtain the product.

1.7所述的勿忘我浸泡油通过以下方法制备:The forget-me-not soaking oil described in 1.7 is prepared by the following method:

称取勿忘我40g,浸泡于16倍g/ml油茶籽油中,浸泡20h,于30℃超声提取6h,过滤,取滤液,即得。Weigh 40g of forget-me-not, soak in 16 times g/ml Camellia oleifera seed oil, soak for 20h, ultrasonically extract at 30°C for 6h, filter, and take the filtrate to obtain the product.

1.8所述的一种含天然花果植物精华的营养滋润型护手霜的制备方法包括以下步骤:The preparation method of a kind of nourishing and moisturizing type hand cream containing natural flower and fruit plant essence described in 1.8 comprises the following steps:

a)称取海藻酸钠0.5g,溶于10ml水中,加热至70℃,边加热边搅拌,混合均匀后,静置让其充分溶胀,得海藻酸钠溶液;a) Weigh 0.5 g of sodium alginate, dissolve it in 10 ml of water, heat to 70° C., stir while heating, mix evenly, let it stand still to fully swell, and obtain sodium alginate solution;

b)称取羟丙基甲基纤维素0.5g,分散于12ml蒸馏水中,迅速搅拌至均匀,静置,自然溶胀7h,待用;b) Weigh 0.5 g of hydroxypropyl methylcellulose, disperse it in 12 ml of distilled water, stir rapidly until uniform, let stand, and swell naturally for 7 hours, and set aside;

c)称取乳木果油3.0g、马油2.0g、小麦胚芽油2.0g、玫瑰浸泡油2g、雪莲花浸泡油2.0g、勿忘我浸泡油1.0g、万用自乳化复合型乳化剂AC-4022.0g置于烧杯中于水浴锅上保持温度70℃水浴加热熔融,作为油相;c) Weigh 3.0g shea butter, 2.0g horse oil, 2.0g wheat germ oil, 2g rose soaking oil, 2.0g snow lotus soaking oil, 1.0g forget-me-not soaking oil, universal self-emulsifying compound emulsifier AC -4022.0g is placed in a beaker, heated and melted on a water bath at a temperature of 70°C, and used as the oil phase;

d)称取蒸馏水20.0g、25%三乙醇胺溶液2.0g、置于70℃水浴加热,得到水相;d) Weighing 20.0 g of distilled water and 2.0 g of 25% triethanolamine solution, heating in a water bath at 70° C. to obtain an aqueous phase;

e)称取Liponic EG-12.0g、1-2丙二醇3.0g、生物多糖胶3.0g、步骤a)制备的海藻酸钠溶液、步骤b)制备的羟丙基甲基纤维素溶液,升温至90℃,搅拌均匀,得到增稠剂;e) Weigh Liponic EG-12.0g, 1-2 propylene glycol 3.0g, biopolysaccharide gum 3.0g, the sodium alginate solution prepared in step a), the hydroxypropyl methylcellulose solution prepared in step b), and heat up to 90 °C, stir evenly to obtain a thickener;

f)待油相完全熔融,将水相倒入油相中,边加边向同一方向搅拌,至呈均匀乳白色膏状,即得基质,将基质冷至室温;f) After the oil phase is completely melted, pour the water phase into the oil phase, and stir in the same direction while adding, until it becomes a uniform milky white paste, that is, the matrix is obtained, and the matrix is cooled to room temperature;

g)称取蜂蜜0.5g、海藻糖0.5g、烟酰胺0.4g、维生素E 0.2g、20%尿素溶液1.0g、白芨提取液0.2g、绿茶提取液0.3g、火棘果榨取液1.0g、猕猴桃榨取液1.0g,搅拌混合均匀,加入冷却后的基质中,得到乳霜膏体;g) Weigh 0.5g of honey, 0.5g of trehalose, 0.4g of nicotinamide, 0.2g of vitamin E, 1.0g of 20% urea solution, 0.2g of Bletilla striata extract, 0.3g of green tea extract, 1.0g of Pyracantha fruit extract, Kiwi fruit extract 1.0g, stir and mix evenly, add to the cooled base to obtain cream paste;

h)将步骤g)所得的乳霜膏体加入步骤e)所制的增稠剂,搅拌10min,混合均匀,再加入10%柠檬酸溶液0.2g,调节pH为6.9;h) Add the cream paste obtained in step g) to the thickener prepared in step e), stir for 10 minutes, mix well, then add 0.2 g of 10% citric acid solution, and adjust the pH to 6.9;

i)最后加入1%乙二胺四乙酸二钠溶液0.2g、5%尼泊金乙酯醇溶液0.5g,所用乙醇浓度为75%,1%香精0.02份搅拌均匀,即得含天然花果植物精华的营养滋润型护手霜。i) Finally, add 0.2 g of 1% disodium edetate solution, 0.5 g of 5% ethylparaben alcohol solution, the concentration of ethanol used is 75%, and 0.02 parts of 1% essence are stirred evenly to obtain natural flowers and fruits Nutritious and moisturizing hand cream with plant extracts.

实施例2Example 2

2.1所述的白芨提取液是通过以下方法制备:The bletilla striata extract described in 2.1 is prepared by the following method:

称取白芨30g,浸泡0.15h,加热至90℃,煎煮提取3次,第1次加11倍量水,提取1.5h,第2次加8倍量水,提取1h,第3次加5倍量水,提取1h,每次滤过,合并滤液,滤液的体积浓缩至白芨重量的5倍g/ml,过滤,取滤液,即得。Weigh 30g of Bletilla striata, soak for 0.15h, heat to 90°C, decoct and extract 3 times, add 11 times the amount of water for the first time, extract for 1.5h, add 8 times the amount of water for the second time, extract for 1h, and add 5 times the amount for the third time Double the amount of water, extract for 1 hour, filter each time, combine the filtrates, concentrate the volume of the filtrates to 5 times the weight of Bletilla striata in g/ml, filter, and take the filtrates to obtain the product.

2.2所述的绿茶提取液通过以下方法制备:The green tea extract described in 2.2 is prepared by the following method:

称取绿茶20g,浸泡0.5h,于90℃加热煎煮提取3次,第1次加10倍量水,提取1.5h,第2次加8倍量水,提取1h,第3次加8倍量水,提取1h,每次滤过,合并滤液,滤液的体积浓缩至绿茶重量的5倍g/ml,过滤,取滤液,即得。。Weigh 20g of green tea, soak for 0.5h, heat and decoct at 90°C for 3 times, add 10 times the amount of water for the first time, extract for 1.5 hours, add 8 times the amount of water for the second time, extract for 1 hour, and add 8 times for the third time Measure water, extract for 1 hour, filter each time, combine the filtrates, concentrate the volume of the filtrate to 5 times the weight of green tea g/ml, filter, and take the filtrate to obtain the product. .

2.3所述的猕猴桃榨取液通过以下方法制备:The kiwi fruit extract described in 2.3 is prepared by the following method:

称取新鲜猕猴桃,去皮,切块,称取50g,放入到榨汁机中,并加入8倍的蒸馏水,所得猕猴桃汁用双层纱布滤过5次,取滤液,待用。Weigh fresh kiwi fruit, peel, cut into pieces, weigh 50g, put it into a juice extractor, and add 8 times of distilled water, filter the gained kiwi fruit juice 5 times with double-layer gauze, take the filtrate, and set aside.

2.4所述的火棘果榨取液通过以下方法制备:The extracting liquid of fireacthorn fruit described in 2.4 is prepared by the following method:

称取新鲜火棘果50g,放入到榨汁机中,并加入10倍的蒸馏水,所得火棘果汁用双层纱布滤过5次,取滤液,待用。Weigh 50g of fresh Pyracantha fruit, put it into a juice extractor, and add 10 times of distilled water, filter the obtained Pyracantha fruit juice for 5 times with double-layer gauze, take the filtrate, and set aside.

2.5所述的玫瑰浸泡油取物通过以下方法制备:The rose soaked oil extract described in 2.5 is prepared by the following method:

称取干玫瑰30g,浸泡于12倍g/ml玉米油中,浸泡18h,于50℃超声提取6h,过滤,取滤液,即得。Weigh 30g of dried rose, soak in 12 times g/ml corn oil, soak for 18h, ultrasonically extract at 50°C for 6h, filter, and take the filtrate to obtain the product.

2.6所述的雪莲花浸泡油通过以下方法制备:The snow lotus soaking oil described in 2.6 is prepared by the following method:

称取干雪莲花40g,浸泡于16倍g/ml玉米油中,浸泡20h,于50℃超声提取6h,过滤,取滤液,即得。Weigh 40g of dried snow lotus, soak in 16 times g/ml corn oil, soak for 20h, ultrasonically extract at 50°C for 6h, filter, and take the filtrate to obtain the product.

2.7勿忘我浸泡油的制备:2.7 Preparation of forget-me-not soaking oil:

称取勿忘我50g,浸泡于15倍g/ml油茶籽油中,浸泡20h,于45℃超声提取5h,过滤,取滤液,即得。Weigh 50g of forget-me-not, soak in 15 times g/ml Camellia oleifera seed oil, soak for 20h, ultrasonically extract at 45°C for 5h, filter, and take the filtrate to obtain the product.

2.8所述的一种含天然花果植物精华的营养滋润型护手霜的制备方法,括以下步骤:The preparation method of a kind of nourishing and moisturizing type hand cream containing natural flower and fruit plant essence described in 2.8 comprises the following steps:

a)称取海藻酸钠0.3g,溶于8ml水中,加热至80℃,边加热边搅拌,混合均匀后,静置让其充分溶胀,得海藻酸钠溶液;a) Weigh 0.3 g of sodium alginate, dissolve it in 8 ml of water, heat to 80° C., stir while heating, mix evenly, let stand to allow it to fully swell, and obtain a sodium alginate solution;

b)称取羟丙基甲基纤维素0.3g,分散于9ml水中,迅速搅拌至均匀,静置,自然溶胀7h,待用;b) Weigh 0.3 g of hydroxypropyl methylcellulose, disperse it in 9 ml of water, stir rapidly until uniform, let stand, and swell naturally for 7 hours, and set aside;

c)称取乳木果油1.0g、马油1.0g、小麦胚芽油1.0g、玫瑰浸泡油1.0g、雪莲花浸泡油2.0g、勿忘我浸泡油2.0g、万用自乳化复合型乳化剂AC-4022.0g置于烧杯中于水浴锅上保持温度80℃水浴加热熔融,作为油相;c) Weigh 1.0g shea butter, 1.0g horse oil, 1.0g wheat germ oil, 1.0g rose soaking oil, 2.0g snow lotus soaking oil, 2.0g forget-me-not soaking oil, universal self-emulsifying compound emulsifier Put 2.0g of AC-402.0g in a beaker, heat and melt on a water bath at a temperature of 80°C, and use it as the oil phase;

d)称取蒸馏水25.0g、25%三乙醇胺溶液2.0g、置于80℃水浴加热,得到水相;d) Weighing 25.0 g of distilled water and 2.0 g of 25% triethanolamine solution, heating in a water bath at 80° C. to obtain an aqueous phase;

e)称取Liponic EG-12.0g、1-2丙二醇3.0g、生物多糖胶5.0g、步骤a)制备的海藻酸钠溶液、步骤b)制备的羟丙基甲基纤维素溶液升温至80℃,搅拌均匀,得到增稠剂;e) Weigh Liponic EG-12.0g, 1-2 propylene glycol 3.0g, biopolysaccharide gum 5.0g, sodium alginate solution prepared in step a), hydroxypropyl methylcellulose solution prepared in step b) and heat up to 80°C , stir evenly to obtain a thickener;

f)待油相完全熔融,将水相倒入油相中,边加边向同一方向搅拌,至呈均匀乳白色膏状,即得基质,将基质冷至室温;f) After the oil phase is completely melted, pour the water phase into the oil phase, and stir in the same direction while adding, until it becomes a uniform milky white paste, that is, the matrix is obtained, and the matrix is cooled to room temperature;

g)称取蜂蜜0.5g、海藻糖1.0g、烟酰胺0.2g、维生素E 0.1g、20%尿素溶液2.0g、白芨提取液0.5g、绿茶提取液0.5g、火棘果榨取液0.5g、猕猴桃榨取液0.5g,搅拌混合均匀,加入冷却后的基质中,得到乳霜膏体;g) Weigh 0.5g of honey, 1.0g of trehalose, 0.2g of nicotinamide, 0.1g of vitamin E, 2.0g of 20% urea solution, 0.5g of Bletilla striata extract, 0.5g of green tea extract, 0.5g of Pyracantha fruit extract, 0.5g of kiwi fruit extract liquid, stirred and mixed evenly, added to the cooled base to obtain cream paste;

h)将步骤g)所得的乳霜膏体加入步骤e)所制的增稠剂,搅拌15min,混合均匀,再加入10%柠檬酸溶液0.2g,调节pH为6.7;h) Add the cream paste obtained in step g) to the thickener prepared in step e), stir for 15 minutes, mix well, then add 0.2 g of 10% citric acid solution, and adjust the pH to 6.7;

i)最后加入1%乙二胺四乙酸二钠溶液0.5g、5%尼泊金乙酯醇溶液0.5g,其中乙醇浓度为75%,1%香精0.01份搅拌均匀,即得含天然花果植物精华的营养滋润型护手霜。i) Finally, add 0.5 g of 1% disodium edetate solution, 0.5 g of 5% ethylparaben alcohol solution, wherein the ethanol concentration is 75%, 0.01 part of 1% essence and stir evenly to obtain natural flowers and fruits Nutritious and moisturizing hand cream with plant extracts.

实施例3Example 3

实施例1、2的理化指标如下:The physicochemical index of embodiment 1,2 is as follows:

3.1性状3.1 Traits

本品为呈淡粉色,稠度适宜,质地软滑,气味芬芳,细腻均一,涂展性良好,保湿、滋润性良好。This product is light pink in color, suitable in consistency, soft and slippery in texture, fragrant in smell, fine and uniform, good in spreadability, good in moisturizing and nourishing.

3.2pH值检查3.2 pH check

取本品,用pH计测定,测得pH值为6-7之间。Get this product, measure with pH meter, record pH value between 6-7.

3.3冷热试验3.3 Hot and cold test

将护手霜封装于透明化妆品瓶中,于4℃的冰箱冷藏一个月观察无分层现象。于55℃的恒温箱内24h,护手霜无分层、乳化变味等现象。Package the hand cream in a transparent cosmetic bottle and refrigerate it in a refrigerator at 4°C for one month to observe that there is no delamination. In a constant temperature box at 55°C for 24 hours, the hand cream has no delamination, emulsification and odor change.

3.4离心试验3.4 Centrifugal test

将护手霜封装于具塞试管中3000r/min,离心20min,无分层现象。Pack the hand cream in a stoppered test tube at 3000r/min, centrifuge for 20min, no layering phenomenon.

3.5室温放置实验3.5 Placement experiment at room temperature

将实施例1、2所制的护手霜置于化妆品瓶中,室温静置考察6个月,无分层现象,用后感觉无变化,气味无变化,无变质现象。The hand cream prepared in Examples 1 and 2 was placed in a cosmetic bottle, and left standing at room temperature for 6 months, no delamination phenomenon, no change in feeling after use, no change in smell, and no deterioration.

3.6刺激性试验、过敏性实验3.6 Irritation test, allergy test

小白鼠背部剪去毛,分别涂抹按实施例1、2制备的护手霜于剪去毛的部位,和没涂部位进行比较,结果没有刺激性和过敏反应。The hair on the back of the mouse was cut off, and the hand cream prepared according to Examples 1 and 2 was applied to the cut-off area respectively, and compared with the unpainted area, the results showed no irritation and allergic reaction.

取实施例1克涂于志愿者(15-65岁,80人)手面上,过30分钟后观察,均没出现发红,发疹,起泡现象。Get 1 gram of Example and apply it on the hands of volunteers (15-65 years old, 80 people), and observe after 30 minutes, there is no redness, rash, and blistering.

3.7抑制小鼠黑色素细胞中酪氨酸酶活力的实验3.7 Inhibition of tyrosinase activity in mouse melanocytes

按实施例1、2制备的护手霜分别取1g,分别加蒸馏水40ml,稀释备用。将B16黑色素细胞接种于96孔板中,每孔100μl,置培养箱中培养育24h后,添加护手霜稀释液。药物作用3d后,弃去上消液,用pH 6.8聚丁二酸丁二醇酯(PBS)冲洗两遍,每孔加90μl含1%(体积分数)TritonX-100的PBS。冰浴中超声破碎,每孔加10μl 10mmol/L的L-多巴(L-dopa),37℃孵育60min,于475nm处比色,空白孔调零,测各孔吸光度值。Take 1g of the hand cream prepared according to Examples 1 and 2, add 40ml of distilled water respectively, and dilute for later use. B 16 melanocytes were inoculated in a 96-well plate, 100 μl per well, cultured in an incubator for 24 hours, and hand cream dilution was added. After 3 days of drug action, the upper solution was discarded, washed twice with pH 6.8 polybutylene succinate (PBS), and 90 μl of PBS containing 1% (volume fraction) TritonX-100 was added to each well. Sonicate in an ice bath, add 10 μl of 10 mmol/L L-dopa (L-dopa) to each well, incubate at 37°C for 60 min, measure color at 475 nm, set the blank well to zero, and measure the absorbance value of each well.

抑制率%=(1-药物组平均吸光度值÷对照组平均吸光度值)×100%Inhibition rate% = (1- average absorbance value of drug group ÷ average absorbance value of control group) × 100%

3.8抑制小鼠黑色素细胞中黑色素合成实验3.8 Inhibition of melanin synthesis in mouse melanocytes

按实施例1、2制备的护手霜分别取1g,分别加蒸馏水40ml,稀释备用。将来自小鼠的B16黑素瘤细胞以1x105个/ml的密度接种于培养皿,在37℃、5%CO2的条件下培养2d。弃上清液,添加护手霜稀释液,药物作用3d后,弃上清液,PBS洗涤,每孔加入0.5ml胰酶消化细胞3min,每孔加2m1维持液终止消化。吹打混匀后,每种浓度取出0.5ml做细胞计数。其余细胞悬液以2500r/min离心5min,弃上清液,于沉淀中加入NaOH溶液,加热使黑色素溶解,选择490nm波长在酶联免疫检测仪上测吸光度值。Take 1g of the hand cream prepared according to Examples 1 and 2, add 40ml of distilled water respectively, and dilute for later use. B16 melanoma cells from mice were inoculated on culture dishes at a density of 1×10 5 cells/ml, and cultured at 37°C and 5% CO 2 for 2 days. Discard the supernatant and add hand cream diluent. After 3 days of drug action, discard the supernatant, wash with PBS, add 0.5ml of trypsin to each well to digest the cells for 3min, and add 2ml of maintenance solution to each well to stop the digestion. After mixing by pipetting, take out 0.5ml of each concentration for cell counting. The rest of the cell suspension was centrifuged at 2500r/min for 5min, the supernatant was discarded, NaOH solution was added to the precipitate, heated to dissolve the melanin, and the absorbance value was measured on an enzyme-linked immunosorbent assay with a wavelength of 490nm.

黑色素合成抑制率%=[1-(药物孔吸光度值÷药物孔细胞密度)÷(对照孔吸光度值÷对照孔细胞密度)]×100%Melanin synthesis inhibition rate%=[1-(absorbance value of drug well ÷ cell density of drug well) ÷ (absorbance value of control well ÷ cell density of control well)]×100%

3.7-3.8实验结果见表1:3.7-3.8 The experimental results are shown in Table 1:

表1实验结果Table 1 Experimental results

实施例1抑制率(%)Embodiment 1 Inhibition rate (%) 实施例2抑制率(%)Embodiment 2 Inhibition rate (%) 抑制酪氨酸酶活力Inhibition of tyrosinase activity 59.359.3 59.759.7 抑制黑色素合成Inhibit melanin synthesis 65.565.5 67.767.7

实验表明,本护手霜有抑制酪氨酸酶活力,抑制黑色素的合成,也说明该护手霜有美白作用。Experiments show that this hand cream can inhibit the activity of tyrosinase and the synthesis of melanin, which also shows that the hand cream has a whitening effect.

实施例4:Example 4:

滋润修护效果实验Moisturizing effect experiment

通过试用实验来评价实施例1、2的滋润修护效果。利用实施例1、2生产出来的护手霜与市售滋润护手霜进行对比实验。选取25-45岁手部粗糙的女性120名。把她们任意等分成三个组。每天早晚各两次用护手霜搽双手,实施例1组用按实施例1制备的护手霜,实施例2组用按实施例2制备的护手霜,对照组涂抹市售滋润护手霜,连续使用两个月。用肉眼观察手上的改善来评价滋润修护效果。此结果见表2:Evaluate the moisturizing and repairing effect of embodiment 1 and 2 by trial experiment. The hand cream produced by Examples 1 and 2 was compared with the commercially available moisturizing hand cream. Select 120 women with rough hands aged 25-45. Divide them arbitrarily into three groups. Rub hands with hand cream twice a day, morning and evening respectively, Example 1 group uses the hand cream prepared according to Example 1, Example 2 group uses the hand cream prepared according to Example 2, and the control group smears commercially available moisturizing hand cream Cream, used continuously for two months. Use the naked eye to observe the improvement of hands to evaluate the moisturizing and repairing effect. The results are shown in Table 2:

表2滋润修护效果实验结果Table 2 Moisturizing and repairing effect experimental results

有效(人)effective (person) 稍微有效(人)slightly effective (person) 无效(人)invalid (person) 总有效率(%)Total effective rate (%) 实施例1Example 1 3232 55 33 92.4592.45

实施例2Example 2 3434 44 22 95.095.0 对照组control group 23twenty three 1010 77 82.582.5

实施例5:Example 5:

该护手霜综合效果考察Investigation on the Comprehensive Effect of the Hand Cream

以下利用试用感觉来评价实施例1、2制造出的护手霜的功效。采用民意调查评分法,选取80名20-50岁年龄段的女性作为试用对象,任意等分成两组,分别用实施例1、2制备的护手霜搽手部。每天使用两次,使用时间两个月。各项使用效果总分为5分:五分为最高分,表示很好,非常满意;4分为较好;3分为可以接受;3分以下为不好,不能接受。以下为各项平均得分。结果见3表:Next, the efficacy of the hand creams manufactured in Examples 1 and 2 was evaluated by using the trial feeling. Using the public opinion survey scoring method, select 80 women in the age group of 20-50 as trial subjects, divide them into two groups arbitrarily, and rub their hands with the hand cream prepared in Examples 1 and 2 respectively. Use twice a day for two months. The total score of each use effect is 5 points: 5 points are the highest score, which means very good and very satisfied; 4 points are good; 3 points are acceptable; below 3 points are bad and unacceptable. Below are the average scores for each category. The results are shown in Table 3:

表3综合效果考察Table 3 Comprehensive effect investigation

使用效果Effect 实施例1各项平均得分The average score of each item of embodiment 1 实施例2各项平均得分The average score of each item of embodiment 2 修护性Repair 4.84.8 4.94.9 滋养性Nutritious 4.84.8 4.84.8 美白性Whitening 4.54.5 4.64.6 保湿性moisture retention 4.84.8 4.74.7

综上所述,本发明所制的该护手霜有良好的修护、滋润、美白嫩肤、保湿补水的功效,用后皮肤有恢复自然弹性、白皙有光泽。In summary, the hand cream prepared by the present invention has good effects of repairing, moisturizing, whitening and rejuvenating, moisturizing and replenishing water, and the skin recovers its natural elasticity, fairness and luster after use.

Claims (10)

1.一种营养滋润型护手霜,其特征在于,以重量份数计其原料组分及含量为:1. A nourishing and moisturizing type hand cream, characterized in that, its raw material components and content are in parts by weight: 2.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的白芨提取液是通过以下方法制备:2. the nourishing moisturizing type hand cream according to claim 1, is characterized in that, described bletilla striata extract is prepared by the following method: 称取白芨适量,浸泡0.15-1h,加热至90-100℃,煎煮提取3次,第1次加6-12倍量水,提取0.5-2h,第2次加4-10倍量水,提取0.5-1.5h,第3次加3-8倍量水,提取0.5-1.5h,每次滤过,合并滤液,滤液的体积浓缩至白芨重量的3-6倍g/ml,过滤,取滤液,即得。Weigh an appropriate amount of Bletilla striata, soak for 0.15-1h, heat to 90-100°C, decoct and extract 3 times, add 6-12 times the amount of water for the first time, extract for 0.5-2h, add 4-10 times the amount of water for the second time, Extract for 0.5-1.5h, add 3-8 times the amount of water for the third time, extract for 0.5-1.5h, filter each time, combine the filtrate, concentrate the volume of the filtrate to 3-6 times g/ml of the weight of Bletilla striata, filter, and take Filtrate, that is. 3.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的绿茶提取液通过以下方法制备:3. The nourishing and moisturizing hand cream according to claim 1, wherein the green tea extract is prepared by the following method: 称取绿茶适量,浸泡0.15-0.8h,于90-100℃加热煎煮提取3次,第1次加6-12倍量水,提取0.5-2h,第2次加4-10倍量水,提取0.5-1.5h,第3次加3-8倍量水,提取0.5-1.5h,每次滤过,合并滤液,滤液的体积浓缩至绿茶重量的3-6倍g/ml,过滤,取滤液,即得。Weigh an appropriate amount of green tea, soak for 0.15-0.8h, heat and decoct at 90-100°C for extraction 3 times, add 6-12 times the amount of water for the first time, extract for 0.5-2h, add 4-10 times the amount of water for the second time, Extract for 0.5-1.5h, add 3-8 times the amount of water for the third time, extract for 0.5-1.5h, filter each time, combine the filtrate, concentrate the volume of the filtrate to 3-6 times the weight of green tea g/ml, filter, and take Filtrate, that is. 4.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的猕猴桃榨取液通过以下方法制备:4. The nourishing and moisturizing type hand cream according to claim 1, characterized in that, said kiwi fruit extract is prepared by the following method: 称取新鲜猕猴桃,去皮,切块,称取一定量,放入到榨汁机中,并加入8-12倍g/ml的蒸馏水,所得猕猴桃汁用双层纱布滤过3-6次,过滤,取滤液,即得。Weigh fresh kiwi fruit, peel, cut into pieces, weigh a certain amount, put it into a juice extractor, and add 8-12 times g/ml distilled water, and filter the obtained kiwi fruit juice with double-layer gauze for 3-6 times, Filter and take the filtrate, that is, too. 5.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的火棘果榨取液通过以下方法制备:5. The nourishing and moisturizing hand cream according to claim 1, characterized in that, the extract of fireacantha fruit is prepared by the following method: 称取新鲜火棘果一定量,放入到榨汁机中,并加入8-12倍g/ml的蒸馏水,所得火棘果汁用双层纱布滤过3-6次,过滤,取滤液,即得。Weigh a certain amount of fresh Pyracantha fruit, put it into a juice extractor, and add 8-12 times g/ml distilled water, filter the Pyracantha fruit juice with double-layer gauze for 3-6 times, filter, and take the filtrate, namely have to. 6.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的玫瑰浸泡油通过以下方法制备:6. The nourishing and moisturizing type hand cream according to claim 1, wherein the rose soaked oil is prepared by the following method: 称取干玫瑰适量,浸泡于10-18倍g/ml玉米油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of dried rose, soak in 10-18 times g/ml corn oil, soak for 12-24h, ultrasonically extract at 30-60°C for 5-6h, filter, and take the filtrate to obtain the product. 7.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的雪莲花浸泡油通过以下方法制备:7. The nourishing and moisturizing hand cream according to claim 1, characterized in that, the soaked snow lotus oil is prepared by the following method: 称取干雪莲花适量,浸泡于10-18g/ml倍玉米油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of dried snow lotus, soak in 10-18g/ml corn oil, soak for 12-24h, ultrasonically extract at 30-60°C for 5-6h, filter, and take the filtrate to obtain the product. 8.根据权利要求1所述的营养滋润型护手霜,其特征在于,所述的勿忘我浸泡油通过以下方法制备:8. The nourishing and moisturizing hand cream according to claim 1, wherein the forget-me-not soaking oil is prepared by the following method: 称取勿忘我适量,浸泡于10-18倍油茶籽油中,浸泡12-24h,于30-60℃超声提取5-6h,过滤,取滤液,即得。Weigh an appropriate amount of forget-me-not, soak it in 10-18 times the camellia seed oil, soak it for 12-24 hours, extract it ultrasonically at 30-60°C for 5-6 hours, filter it, and take the filtrate. 9.所述的香精为玫瑰香精、水蜜桃香精、菠萝香精、柠檬香精、青瓜香精、茉莉香精、桂花香精中的一种。9. The essence is one of rose essence, peach essence, pineapple essence, lemon essence, cucumber essence, jasmine essence, osmanthus essence. 10.一种权利要求1所述的营养滋润型护手霜的制备方法,其特征在于,所述方法包括以下步骤:10. A preparation method of the nourishing and moisturizing type hand cream according to claim 1, characterized in that, the method comprises the following steps: a)称取海藻酸钠0.01-0.5份,溶于1-10份蒸馏水中,加热至60-80℃,边加热边搅拌,混合均匀后,静置让其充分溶胀,得海藻酸钠溶液;a) Weigh 0.01-0.5 parts of sodium alginate, dissolve in 1-10 parts of distilled water, heat to 60-80°C, stir while heating, mix evenly, let stand to let it fully swell, and obtain sodium alginate solution; b)称取羟丙基甲基纤维素0.01-0.5份,分散于5-12份蒸馏水中,迅速搅拌至均匀,静置,自然溶胀5-7h,待用;b) Weigh 0.01-0.5 parts of hydroxypropyl methylcellulose, disperse in 5-12 parts of distilled water, stir rapidly until uniform, let stand, and swell naturally for 5-7 hours, and set aside; c)称取乳木果油0.5-5.0份、马油0.2-5.0份、小麦胚芽油1.0-5.0份、玫瑰浸泡油1.0-5.0份、雪莲花浸泡油1.0-5.0份、勿忘我浸泡油1.0-5.0份、万用自乳化复合型乳化剂AC-4021.0-5.0份置于烧杯中于水浴锅上保持温度60-90℃水浴加热熔融,作为油相;c) Weigh 0.5-5.0 parts of shea butter, 0.2-5.0 parts of horse oil, 1.0-5.0 parts of wheat germ oil, 1.0-5.0 parts of rose soaking oil, 1.0-5.0 parts of snow lotus soaking oil, and 1.0 parts of forget-me-not soaking oil -5.0 parts, universal self-emulsifying compound emulsifier AC-402 1.0-5.0 parts are placed in a beaker, heated and melted in a water bath at a temperature of 60-90 ° C, as the oil phase; d)称取蒸馏水4.0-50.0份、25%三乙醇胺溶液1.0-5.0份、置于60-90℃水浴加热,得到水相;d) Weighing 4.0-50.0 parts of distilled water and 1.0-5.0 parts of 25% triethanolamine solution, heating in a water bath at 60-90°C to obtain an aqueous phase; e)称取Liponic EG-1 1.0-5.0份、1-2丙二醇1.0-5.0份、生物多糖胶2.0份-5.0份、步骤a)制备的海藻酸钠溶液、步骤b)制备的羟丙基甲基纤维素溶液,加热升温至80-90℃,搅拌均匀,得到增稠剂;e) Weigh 1.0-5.0 parts of Liponic EG-1, 1.0-5.0 parts of 1-2 propylene glycol, 2.0-5.0 parts of biopolysaccharide gum, the sodium alginate solution prepared in step a), and the hydroxypropyl methyl alcohol prepared in step b). Base cellulose solution, heating up to 80-90°C, stirring evenly to obtain a thickener; f)待油相完全熔融,将水相倒入油相中,边加边向同一方向搅拌,至呈均匀乳白色膏状,即得基质,将基质冷至室温;f) After the oil phase is completely melted, pour the water phase into the oil phase, and stir in the same direction while adding, until it becomes a uniform milky white paste, that is, the matrix is obtained, and the matrix is cooled to room temperature; g)称取蜂蜜0.1-2.0份、海藻糖0.5-5.0份、烟酰胺0.01-1.0份、维生素E 0.1-1.0份、20%尿素溶液1.0-5.0份、白芨提取液0.1-3.0份、绿茶提取液0.1-3.0份、火棘果榨取液0.1-3.0份、猕猴桃榨取液0.1-3.0份,搅拌混合均匀,加入冷却后的基质中,得到乳霜膏体;g) Weigh 0.1-2.0 parts of honey, 0.5-5.0 parts of trehalose, 0.01-1.0 parts of nicotinamide, 0.1-1.0 parts of vitamin E, 1.0-5.0 parts of 20% urea solution, 0.1-3.0 parts of Bletilla striata extract, green tea extract 0.1-3.0 parts of liquid, 0.1-3.0 parts of Pyracantha fruit extract, 0.1-3.0 parts of kiwifruit extract, stir and mix evenly, add to the cooled base to obtain cream paste; h)向步骤g)所得的乳霜膏体加入步骤e)所制的增稠剂,搅拌10-15min,混合均匀,再加入10%柠檬酸溶液0.1-5.0份,调节pH在6-7之间;h) Add the thickener prepared in step e) to the cream paste obtained in step g), stir for 10-15 minutes, mix well, then add 0.1-5.0 parts of 10% citric acid solution, and adjust the pH between 6-7 between; i)最后加入1%乙二胺四乙酸二钠溶液0.01-5.0份、5%尼泊金乙酯醇溶液0.01-5.0份,其中乙醇浓度为75%,1%香精0.01-0.05份,搅拌均匀,即得含天然花果植物精华的营养滋润型护手霜。i) Finally, add 0.01-5.0 parts of 1% disodium edetate solution, 0.01-5.0 parts of 5% ethylparaben alcohol solution, wherein the ethanol concentration is 75%, 0.01-0.05 parts of 1% essence, and stir well , that is, a nourishing and moisturizing hand cream containing natural flower and fruit plant extracts.
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CN107569432A (en) * 2017-08-29 2018-01-12 皖南医学院 A kind of draft nourishes hand lotion of the white moisturizing of releiving of profit and preparation method thereof
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CN108309848B (en) * 2018-03-27 2020-08-04 上海清轩生物科技有限公司 Preparation method of chlorella extract and anti-aging composition thereof
CN108542851A (en) * 2018-06-28 2018-09-18 芜湖扬展新材料科技服务有限公司 A kind of Chinese medicine moisturizing anti-chapping hand cream and preparation method thereof
CN109820842A (en) * 2018-11-20 2019-05-31 中国科学院昆明植物研究所 Application of yam Ⅲ in the preparation of medicines and cosmetics
CN109820860A (en) * 2019-04-19 2019-05-31 江苏远恒药业有限公司 A kind of Compound Miconazole nitrate Cream and its preparation process
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