CN104430370A - Fungicidal composition - Google Patents
Fungicidal composition Download PDFInfo
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- CN104430370A CN104430370A CN201410602518.2A CN201410602518A CN104430370A CN 104430370 A CN104430370 A CN 104430370A CN 201410602518 A CN201410602518 A CN 201410602518A CN 104430370 A CN104430370 A CN 104430370A
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- CN
- China
- Prior art keywords
- zen
- acid amides
- fluorobenzene ether
- ether acid
- water dispersible
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- 239000000203 mixture Substances 0.000 title claims abstract description 22
- 230000000855 fungicidal effect Effects 0.000 title abstract description 4
- 239000004562 water dispersible granule Substances 0.000 claims abstract description 13
- 239000000375 suspending agent Substances 0.000 claims abstract description 5
- -1 fluorobenzene ether acid amides Chemical class 0.000 claims description 25
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 24
- 230000000844 anti-bacterial effect Effects 0.000 claims description 11
- 239000000463 material Substances 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 abstract description 9
- 239000000575 pesticide Substances 0.000 abstract description 5
- 239000005818 Picoxystrobin Substances 0.000 abstract description 2
- IBSNKSODLGJUMQ-SDNWHVSQSA-N picoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1COC1=CC=CC(C(F)(F)F)=N1 IBSNKSODLGJUMQ-SDNWHVSQSA-N 0.000 abstract description 2
- 150000001408 amides Chemical class 0.000 abstract 1
- 241000209094 Oryza Species 0.000 description 15
- 235000007164 Oryza sativa Nutrition 0.000 description 15
- 235000009566 rice Nutrition 0.000 description 15
- 239000003814 drug Substances 0.000 description 14
- 201000010099 disease Diseases 0.000 description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 13
- 230000002195 synergetic effect Effects 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 230000003449 preventive effect Effects 0.000 description 7
- 239000002131 composite material Substances 0.000 description 6
- 230000003902 lesion Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 4
- 241001530056 Athelia rolfsii Species 0.000 description 3
- 241000813090 Rhizoctonia solani Species 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 230000002045 lasting effect Effects 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010039509 Scab Diseases 0.000 description 2
- 241000209140 Triticum Species 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 239000003905 agrochemical Substances 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 244000144730 Amygdalus persica Species 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 241000221785 Erysiphales Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 235000006040 Prunus persica var persica Nutrition 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003958 fumigation Methods 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 230000005405 multipole Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of pesticides, and relates to a fungicidal composition. The fungicidal composition is characterized in that active ingredients comprise picoxystrobin and fluorophenylate amide. The composition can be prepared into a suspending agent and a water dispersible granule, the synergism is obvious, and the composition is environmentally friendly.
Description
Technical field
The invention belongs to technical field of pesticide, contain the bactericidal composition with synergistic effect of ZEN 90160 and fluorobenzene ether acid amides specifically.
Background technology
ZEN 90160 (Picoxystrobin) is systemic fungicide, controlling object wide spectrum, is mainly used in the foliage disease of control wheat class and paddy rice as banded sclerotial blight, leaf rust, glume blight, brown spot, powdery mildew etc.This active ingredient belongs to mitochondrial respiratory inhibitor, and due to systemic activity and the fumigation activity of ZEN 90160, thus after dispenser, active ingredient can effectively be reallocated and fully transmit, and compares other compositions, and ZEN 90160 has better result for the treatment of.
Fluorobenzene ether acid amides is Central China Normal University's pyrazol acid amide compounds newly developed, has good preventive effect to the banded sclerotial blight of paddy rice and wheat, also has certain control efficiency to the epidemic disease of the crop such as cucumber, tomato and sigatoka simultaneously.
Rice sheath blight disease, is infected by Rhizoctonia solani Kuhn to fall ill, how falls ill under high temperature, super-humid conditions.Banded sclerotial blight is serious in the harm of south rice region, is one of Major Diseases in current Rice Production.This disease can make paddy rice not ear, and particle weight declines.
Due to the use lack of standardization of current agricultural chemicals, cause disease more and more stronger to the resistance of agricultural chemicals, cause Pesticide use amount more and more higher, cause the pollution of environment.Shown by our experiment and relevant report, combined use of pesticides can be good at the deficiency overcoming existing product, improves drug effect, reduces usage amount.
Summary of the invention
The object of this invention is to provide a kind of bactericidal composition with synergistic effect, for the water prevention rice sheath blight, compared with existing pesticide control, realize the object improving drug effect.Be specifically related to the bactericidal composition of ZEN 90160 and fluorobenzene ether acid amides.
Utilize above-mentioned bactericidal composition, be equipped with the known auxiliary agent of those skilled in that art, make formulation of the present invention with the known method of those skilled in that art, formulation of the present invention is suspending agent and water dispersible granules.
In above-mentioned bactericidal composition, the weight ratio of ZEN 90160 and fluorobenzene ether acid amides is 1:50-50:1.
Above-mentioned bactericidal composition has following characteristics: 1. use complex preparation, has good synergistic effect; 2. the active ingredient mode of action is unique, with existing bactericide without cross resistance; 3. to crop safety, environmentally friendly; 4. bactericidal action is fast, and the lasting period is long.
In order to verify two kinds of active ingredients composite after synergistic effect, first applicant uses these two kinds of compositions to carry out indoor biometrics test, according to the mode of action of active ingredient, the raw object surveyed is decided to be thanatephorus cucumeris(frank) donk by us, this Pseudomonas Basidiomycotina fungi, sclerotium is dark brown, and bacterium colony is light brown to taupe mildew, can cause rice sheath blight disease.
The test method of indoor biometrics: reference standard NY/T1156.6-2006, adopts growth rate method to measure medicament to the inhibitory action of rice sheath blight disease pathogen mycelial growth.On the basis of preliminary experiment, from each medicament, design 5 concentration within the scope of 10%-90% are reached to germ mycelial growth inhibition rate, it is for subsequent use by the former medicine of 96% ZEN 90160 and the former medicine of 95% fluorobenzene ether acid amides with acetone to be first that solvent is made into the liquid of series concentration, then liquid is joined in 1% ratio in the PDA medium melting also cool to room temperature, after fully shaking up, pour in the culture dish (Φ 90mm) of sterilizing and make band medicine flat board, often process and repeat, to add the process of sterile water for blank for four times; With card punch (Φ 5mm) the picking Rhizoctonia solani Kuhn bacterium cake of sterilizing, mycelia faces down aseptic inoculation in the central authorities of band medicine flat board, be inverted in the interior cultivation of constant incubator of 25 DEG C, adopt right-angled intersection method to measure colony diameter after cultivating 6d, calculate the EC of each medicament to pathogen
50, and calculate toxicity index according to the following equation, compare virulence and the bacteriostasis of different agents.Former medicine used is tested in above-mentioned raw test and reagent is all bought from other producers.
The co-toxicity coefficient method representation that the co-toxicity of mixture preparation adopts Sun Yun abundant:
The theoretical toxicity index TTI=∑ of mixture preparation (percentage of this pharmaceutically active ingredient of the toxicity index ATI of certain medicine × in mixture).
Be synergistic effect when co-toxicity coefficient CTC is greater than 120, being antagonism when being less than 80, is addition time between 80-120.
Table 1 ZEN 90160 and fluorobenzene ether acid amides and different ratio thereof are to the measurement result of rice sheath blight disease co-toxicity coefficient
Shown by above-mentioned data, when ZEN 90160 and fluorobenzene ether acid amides are composite in varing proportions, the co-toxicity coefficient (CTC) of formula is all greater than 120, has obvious synergistic effect to the control efficiency of rice sheath blight disease.
Tested by indoor biometrics, checking ZEN 90160 and fluorobenzene ether acid amides two kinds of active ingredients composite after, have good synergistic effect, below by way of instantiation in order to further describe the present invention, but the present invention is absolutely not only only limitted to these embodiments following.In formula, percentage is all weight percentage, and the former medicine used and auxiliary agent are other producers and buy.
Formulation examples is as follows:
Example one, 40.8% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example two, 51% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example three, 26% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example four, 13% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example five, 33% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example six, 44% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example seven, 12% ZEN 90160 fluorobenzene ether amide suspending agents
Example eight, 18% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example nine, 30% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Example ten, 20% ZEN 90160 fluorobenzene ether acid amides water dispersible granules
Select above example to carry out the field trial of the water prevention rice sheath blight, simultaneously by the Contrast on effect with ZEN 90160 and fluorobenzene ether acid amides single dose, verify composite after synergistic effect.Test site is peach of immortality area, Hubei Province, and the time is on July 25th, 2013, and test each process three repetition, community randomized arrangement, each plot area is 70m
2, adopt back-pack electric compression sprayer, dispenser was sunny calm for the same day, and the planting habit of planting habit all with local of all communities is identical, records the synoptic data on the dispenser same day and a week thereafter, specific as follows:
Table 2 duration of test meteorological data
Investigation method is with reference to GB/T 17980.34-2000, each community diagonal 5 sampling, often some sampling 2-3 strain, investigate fixed 2 points of whole blade each community diagonal, often fixed 25 clumps of paddy rice of straight ahead, fixed point investigation in the 7th day, 21 days after dispenser, investigate each community disease to refer to, calculate preventive effect, and carry out the new multipole difference analysis of Deng Kenshi, calculate according to following grade scale:
0 grade: without scab;
1 grade: lesion area accounts for less than 5% of whole leaf area;
3 grades: lesion area accounts for 6% ~ 10% of whole leaf area;
5 grades: lesion area accounts for 11% ~ 25% of whole leaf area;
7 grades: lesion area accounts for 26% ~ 50% of whole leaf area;
9 grades: lesion area accounts for more than 51% of whole leaf area, stem stalk there is scab.
Computing formula is as follows:
Table 3 30% ZEN 90160 fluorobenzene ether acid amides water dispersible granules and different agents are to the preventive effect of rice sheath blight disease
Analyze above-mentioned data to draw, ZEN 90160 and fluorobenzene ether acid amides composite after after medicine 7 days preventive effects all more than 70%, and 75% ZEN 90160 wetting powder, 7 days preventive effects after medicine are 43.50%, the preventive effect of 24% fluorobenzene ether amide suspending agents is 36.67%, visible, there is good synergistic effect after two kinds of active ingredients are composite.And after medicine 21 days, all complex preparations to be all better than after medicine 7 days to the preventive effect of rice sheath blight disease, and extend the lasting period, control efficiency is more lasting.
Claims (2)
1. a bactericidal composition, is characterized in that: active component is made up of ZEN 90160 and fluorobenzene ether acid amides, and the weight ratio of described ZEN 90160 and fluorobenzene ether acid amides is 1:50 ~ 50:1.
2. bactericidal composition according to claim 1, is characterized in that: make suspending agent, water dispersible granules by active component and auxiliary material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410602518.2A CN104430370A (en) | 2014-10-31 | 2014-10-31 | Fungicidal composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410602518.2A CN104430370A (en) | 2014-10-31 | 2014-10-31 | Fungicidal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104430370A true CN104430370A (en) | 2015-03-25 |
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ID=52877726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410602518.2A Pending CN104430370A (en) | 2014-10-31 | 2014-10-31 | Fungicidal composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104430370A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106561667A (en) * | 2016-11-14 | 2017-04-19 | 江西正邦生物化工有限责任公司 | Bactericide composite containing C19H13ClF5N302 |
| CN107006479A (en) * | 2016-01-28 | 2017-08-04 | 响水县智诚知识产权信息服务有限公司 | A kind of bactericidal composition containing SYP-3375 Yu fluorobenzene ether amide |
| CN107372688A (en) * | 2017-07-28 | 2017-11-24 | 安徽省圣丹生物化工有限公司 | A kind of bactericide for treating the withered line disease of rice |
| CN109418271A (en) * | 2017-09-04 | 2019-03-05 | 浙江省化工研究院有限公司 | A kind of bactericidal composition of fluorine-containing phenylate amide and methoxy acrylic bactericide |
| CN111280170A (en) * | 2018-12-07 | 2020-06-16 | 东莞市东阳光菌阳氢专利农药有限公司 | Bactericidal composition and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103891723A (en) * | 2012-12-31 | 2014-07-02 | 江苏丰登农药有限公司 | Bactericidal composition containing isopyrazam and picoxystrobin and application thereof |
-
2014
- 2014-10-31 CN CN201410602518.2A patent/CN104430370A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103891723A (en) * | 2012-12-31 | 2014-07-02 | 江苏丰登农药有限公司 | Bactericidal composition containing isopyrazam and picoxystrobin and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 梁英等: "具有杀菌活性的吡唑类衍生物的研究进展", 《农药》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107006479A (en) * | 2016-01-28 | 2017-08-04 | 响水县智诚知识产权信息服务有限公司 | A kind of bactericidal composition containing SYP-3375 Yu fluorobenzene ether amide |
| CN106561667A (en) * | 2016-11-14 | 2017-04-19 | 江西正邦生物化工有限责任公司 | Bactericide composite containing C19H13ClF5N302 |
| CN107372688A (en) * | 2017-07-28 | 2017-11-24 | 安徽省圣丹生物化工有限公司 | A kind of bactericide for treating the withered line disease of rice |
| CN109418271A (en) * | 2017-09-04 | 2019-03-05 | 浙江省化工研究院有限公司 | A kind of bactericidal composition of fluorine-containing phenylate amide and methoxy acrylic bactericide |
| CN111280170A (en) * | 2018-12-07 | 2020-06-16 | 东莞市东阳光菌阳氢专利农药有限公司 | Bactericidal composition and application thereof |
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Application publication date: 20150325 |