CN104288381A - Medicinal liquor for treating arthralgia and production method thereof - Google Patents

Abstract

The invention discloses medicinal liquor for treating arthralgia and a production method thereof. The medicinal liquor, through notopterygium root, radix angelicae pubescentis, divaricate saposhnikovia root, ephedra, anisetree bark (schizophragma integrifolium oliv) and wooly datchmanspipe herb in traditional Chinese medicine raw materials, can achieve a purpose of treating symptoms; prepared rehmannia root, ligamentum cervi, pangolin, root of bidentate achyranthes, Qianlijian and cortex acanthopanacis function as nourishing liver and kidney, and expelling wind-damp to achieve a purpose of treating root causes; radix aconiti, radix aconiti kusnezoffii, cassia twig, ephedra, divaricate saposhnikovia root and cortex cinnamomi are excellent in unblocking ying and wei, expelling wind-damp and relieving persistent pain; radix aconiti carmichaeli and common club moss herb function as warming yang and promoting blood circulation; radix clematidis takes effects of nourishing liver and kidney, strengthening muscles and bones, and expelling wind-damp; the medicinal liquor, blended in brown sugar and wine, is used for replenishing blood, unblocking meridians and dispelling cold; various medicines, including monarch, minister, assistant and guide, are combined, so as to realize functions of dispelling wind-damp, relieving impediment pain, benefiting liver and kidney, strengthening muscles and bones, and unblocking ying and wei, and to achieve a purpose of treatment. The selected traditional Chinese medicines are cleaned, dried, ground, decocted, concentrated, blended in wine, filling in a clean vessel and sealing the vessel to obtain a finished product. Through a great amount of clinical tests in long time, it proves that an effective rate is more than 98%.

Description

A kind of medicated wine and production method thereof being used for the treatment of arthralgia

Technical field

The present invention relates to a kind of medicated wine being used for the treatment of arthritis/rheumatism/rheumatoid arthrosis pain, particularly a kind of medicated wine and production method thereof being used for the treatment of arthralgia.It is primary treatment principle with " promoting the circulation of blood of enriching blood, dehumidifying cold expelling, wind dispelling relieving convulsion, the numbness that disappears eliminating stagnation ", selects pure natural medical, through decocting, after concentrated and wine mixing to be placed on hermetic container interior after certain hour, be finished product.

Background technology

The traditional Chinese medical science is thought " general rule not bitterly; pain is then obstructed ", all arthralgias, rheumatism, rheumatoid arthrosis pain and the muscular soreness caused by rheumatism, rheumatoid, be all be detained in meridians by wind-cold damp pathogen, caused by QI-blood circulation is not smooth, cause joint activities adverse, local pain is numb, limitation of activity, has a strong impact on the orthobiosis of patient, and patient's body and mind is among misery.The diseases such as the said rheumatism of western medicine, rheumatoid arthritis, ankylosing spondylitis, cervical spondylosis, scapulohumeral periarthritis, waist hamstring bone pain, puerperal exposure to wind pain disease, osteonecrosis of femoral head, sciatica, numb limbs and tense tendons, muscle arteries and veins contraction urgency, the traditional Chinese medical science is referred to as " arthromyodynia ".Generally, " arthromyodynia " is roughly divided into wind, cold, wet, hot Four types.But in the actual course of disease, except beriberoid pyretic arthralgia, wind, cold, wet heresy often alternately occurs.That is, at a rheumatism patient, not only have ailment said due to cold or exposure, and the excessive of cold-damp exists simultaneously.Arthralgia is rheumatism, the global difficult and complicated illness of rheumatoid disease system, because the cold pain disease traditional Chinese medical science caused by cold-evil is referred to as " arthralgia aggravated by cold ", because the redness and swelling of joints burning pain traditional Chinese medical science caused by catching pathogenic heat is referred to as " beriberoid pyretic arthralgia ".Up to the present, because the specific drug that can decompose and eliminate rheumatism focus does not appear in the world of medicine, cause extensive patients to be in for a long time among ailing torment.Rheumatic osteopathia endangers big to patient, prolongedly do not heal.Especially blowing, rain, in date of the Changes in weather such as cold, moist and solar term conversion, extensive patients can because limbs pain aggravation the shrimp back of the body of bending over, be in very much among misery.Particularly in, late period, extensive patients can the autotomy because muscles and bones distortion.Rheumatism is main with muscle, muscles and bones, the miserable pain in joint in early days, and it is main clinical characteristics that numbness weighs.Along with further developing of the state of an illness, there is enlargement, joint stuffiness in each joint of whole body.Continue development more further, ankylosis, orthotonus, joint loses activity and becomes deformity, and finally causing becomes disabled person because can't take care of oneself.Therefore, capture and defeat anemofrigid-damp arthralgia imperative.

Summary of the invention

In sum, the object of the invention is to develop a kind of medicated wine and production method thereof being used for the treatment of arthralgia.For improving the quality of life of this type of patient, the present invention develops in line with the object for the treatment of both the principal and secondary aspects of a disease, and through long-term a large amount of clinical verification, effective percentage can reach more than 98%.Select 19 taste natural Chinese medicines to be raw material, by the Chinese medicine selected through cleaning, dry, decoct, after decoction liquor mixing again with brown sugar mixing, be finished product after airtight with the clean vessel of wine mixing loading again after concentrated.Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Saposhnikoviae, Herba Ephedrae in formula, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) and Herba Aristolochiae Mollissimae eliminating evil to reach the object of taking stopgap measures; Radix Rehmanniae Preparata, Ligamentum cervi, Squama Manis, Radix Achyranthis Bidentatae, Rhizoma Homalomenae, Cortex Acanthopancis invigorating the liver and kidney, wind-damp dispelling is to reach the object of effecting a permanent cure; Radix Aconiti, Radix Aconiti Kusnezoffii, Ramulus Cinnamomi, Herba Ephedrae, Radix Saposhnikoviae, the logical battalion of Cortex Cinnamomi a surname defends, and wind-damp dispelling is good by Persistent Pain; Radix Aconiti Lateralis Preparata, Herba Lycopodii warming YANG is invigorated blood circulation; Radix Clematidis invigorating the liver and kidney, strengthening bone and muscle, wind-damp dispelling; To enrich blood dredging collateral cold expelling for drawing with brown sugar and wine, all medicines share, monarch, and to reach wind-damp dispelling, stopping numbness pain, liver and kidney tonifying, strengthening bone and muscle, effect that logical battalion defends, reaches therapeutic purposes.

For achieving the above object, the technical solution used in the present invention is:

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 10 ~ 20 parts, Rhizoma Et Radix Notopterygii 5 ~ 15 parts, Ramulus Cinnamomi 5 ~ 15 parts, Herba Aristolochiae Mollissimae 5 ~ 15 parts, Radix Angelicae Pubescentis 5 ~ 15 parts, Radix Saposhnikoviae 5 ~ 15 parts, Herba Lycopodii 5 ~ 15 parts, Rhizoma Homalomenae 5 ~ 15 parts, Radix Clematidis 5 ~ 15 parts, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 5 ~ 15 parts, Radix Aconiti Kusnezoffii 2 ~ 10 parts, Radix Achyranthis Bidentatae 2 ~ 10 parts, Cortex Cinnamomi 2 ~ 10 parts, 2 ~ 10 parts, Herba Ephedrae, Radix Aconiti 2 ~ 10 parts, Squama Manis 1 ~ 10 part, Radix Aconiti Lateralis Preparata 1 ~ 8 part, Ligamentum cervi 1 ~ 8 part, Cortex Acanthopancis 5 ~ 20 parts, wine 1000 ~ 2000 parts and 700 ~ 800 parts, brown sugar.

Technical scheme of the present invention can be achieved in that

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 10 parts, Rhizoma Et Radix Notopterygii 5 parts, Ramulus Cinnamomi 5 parts, Herba Aristolochiae Mollissimae 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Saposhnikoviae 5 parts, Herba Lycopodii 5 parts, Rhizoma Homalomenae 5 parts, Radix Clematidis 5 parts, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 5 parts, Radix Aconiti Kusnezoffii 2 parts, Radix Achyranthis Bidentatae 2 parts, Cortex Cinnamomi 2 parts, 2 parts, Herba Ephedrae, Radix Aconiti 2 parts, Squama Manis 1 part, Radix Aconiti Lateralis Preparata 1 part, Ligamentum cervi 1 part, Cortex Acanthopancis 5 parts, wine 1000 parts and 700 parts, brown sugar.

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 15 parts, Rhizoma Et Radix Notopterygii 9 parts, Ramulus Cinnamomi 9 parts, Herba Aristolochiae Mollissimae 9 parts, Radix Angelicae Pubescentis 9 parts, Radix Saposhnikoviae 9 parts, Herba Lycopodii 9 parts, Rhizoma Homalomenae 9 parts, Radix Clematidis 9 parts, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 9 parts, Radix Aconiti Kusnezoffii 6 parts, Radix Achyranthis Bidentatae 6 parts, Cortex Cinnamomi 6 parts, 6 parts, Herba Ephedrae, Radix Aconiti 6 parts, Squama Manis 5 parts, Radix Aconiti Lateralis Preparata 3 parts, Ligamentum cervi 3 parts, Cortex Acanthopancis 12 parts, wine 1500 parts and 750 parts, brown sugar.

Further, described wine is 60 ° of pure jowar wines.

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 20 parts, Rhizoma Et Radix Notopterygii 15 parts, Ramulus Cinnamomi 15 parts, Herba Aristolochiae Mollissimae 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Saposhnikoviae 15 parts, Herba Lycopodii 15 parts, Rhizoma Homalomenae 15 parts, Radix Clematidis 15 parts, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 15 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Achyranthis Bidentatae 10 parts, Cortex Cinnamomi 10 parts, 10 parts, Herba Ephedrae, Radix Aconiti 10 parts, Squama Manis 10 parts, Radix Aconiti Lateralis Preparata 8 parts, Ligamentum cervi 8 parts, Cortex Acanthopancis 20 parts, wine 2000 parts and 800 parts, brown sugar.

Be used for the treatment of a production method for the medicated wine of arthralgia, be made up of following steps:

The first step, by the raw material of Chinese medicine Radix Rehmanniae Preparata 10 ~ 20 part of formula by select, Rhizoma Et Radix Notopterygii 5 ~ 15 parts, Ramulus Cinnamomi 5 ~ 15 parts, Herba Aristolochiae Mollissimae 5 ~ 15 parts, Radix Angelicae Pubescentis 5 ~ 15 parts, Radix Saposhnikoviae 5 ~ 15 parts, Herba Lycopodii 5 ~ 15 parts, Rhizoma Homalomenae 5 ~ 15 parts, Radix Clematidis 5 ~ 15 parts, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 5 ~ 15 parts, Radix Aconiti Kusnezoffii 2 ~ 10 parts, Radix Achyranthis Bidentatae 2 ~ 10 parts, Cortex Cinnamomi 2 ~ 10 parts, 2 ~ 10 parts, Herba Ephedrae, Radix Aconiti 2 ~ 10 parts, Squama Manis 1 ~ 10 part, Radix Aconiti Lateralis Preparata 1 ~ 8 part, Ligamentum cervi 1 ~ 8 part and Cortex Acanthopancis 5 ~ 20 parts screen, cleaning, dry, pulverize, mixing is coarser powder crude drug, be made as A material, for subsequent use,

Second step, by formula consumption, the A of first step material is put in marmite and added clean cold water, add water to and exceed raw material powder 20 centimetres, soaks after 7 hours, decoction;

3rd step, first with big fire be heated to boiling after, use little fire instead, maintain boil to 60 minutes, cross filtrate; Add water appropriate, then decoct, filter, repeatedly twice, merges three filtrates, heating, then adds 700 ~ 800 parts, brown sugar, and limit heating, limit are stirred, and is made as B and expects;

4th step, the 3rd step B material to be left standstill after 8 hours, get supernatant heating and be condensed into paste, after cooling, then add 60 ° of pure jowar wines 1000 ~ 2000 parts, mix after sealing deposits three months in rearmounted hermetic container, get supernatant, be finished product.

Pharmacology of the present invention and literature basis are:

Radix Rehmanniae Preparata: nature and flavor: sweet, tepor.Gui Jing: enter liver, kidney channel.YIN nourishing, enriches blood.For deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency, fills out bone marrow, longue meat.

Rhizoma Et Radix Notopterygii: nature and flavor: pungent, bitter, temperature.Gui Jing: enter bladder, kidney channel.Cold expelling, dispels the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.

Ramulus Cinnamomi: nature and flavor: acrid, sweet, warm.Gui Jing: enter the heart, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus.

Herba Aristolochiae Mollissimae: nature and flavor: bitter is flat.For rheumatic arthritis, carbuncle.

Radix Angelicae Pubescentis: nature and flavor: pungent, bitter, tepor.Gui Jing: enter kidney, urinary bladder channel.Expelling wind and removing dampness, numbness relieving and pain relieving.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache, expelling wind and dampness, numbness relieving and pain relieving, anemofrigid-damp arthralgia, arthralgia.

Radix Saposhnikoviae: nature and flavor: Xin Gan, temperature.Gui Jing: enter bladder, lung, spleen channel.Deliver, dispel the wind, victory is wet, pain relieving.Control affection of exogenous wind-cold, anemofrigid-damp arthralgia, arthralgia, extremity contraction is anxious waits disease.

Herba Lycopodii: nature and flavor: toil, temperature.Gui Jing: enter liver,spleen,kidney warp.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Be mainly used in treating anemofrigid-damp arthralgia, joint aches, tetraparesis, the contracture of muscle arteries and veins, the diseases such as joint stuffiness.

Rhizoma Homalomenae: nature and flavor: pungent, temperature.Gui Jing: enter liver, kidney channel.Loose rheumatism, muscle reinforcing and bone strengthening, stopping numbness pain.Be mainly used in treating anemofrigid-damp arthralgia, chills and pain of the waist and kness, numbness contracture, the diseases such as bones and muscles pain.

Radix Clematidis: pungent, salty, temperature; Slightly poisonous.Return urinary bladder channel.Effect, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Cure mainly for, rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint joint stuffiness, pain is demonstrate,proved, dermatosis.

Cortex Illicii (Cortex schizophragmatis integrifolii radicis) :nature and flavor are micro-pungent, puckery, temperature; Slightly poisonous.Gui Jing: enter spleen; Stomach warp.Expelling wind and removing dampness; Promoting the circulation of QI to relieve pain.Main rheumatic arthritis; Lumbar muscle strain.

Radix Aconiti Kusnezoffii: nature and flavor: pungent, heat, poisonous.Gui Jing: enter spleen, the gate of vitality, hands faint the moon, shaoyin channel.Dispelling cold and dampness, loose ailment said due to cold or exposure, warming the meridian, pain relieving.Control anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, the diseases such as hemiplegia.

Radix Achyranthis Bidentatae: bitter, acid, flat.Return Liver and kidney warp.Effect, promoting blood circulation to restore menstrual flow, ignites descending, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis.Cure mainly for dysmenorrhea amenorrhea, puerperal abdonimal pain, retention of placenta, traumatic injury, the stasis of blood is stagnant has a pain, top syndrome of fire-heat, soreness of waist and knee joint, flaccidity and weakness of the lower limbs, stranguria, edema dysuria, lump in the abdomen.

Cortex Cinnamomi: nature and flavor: pungent, sweet, hot greatly.Gui Jing: enter kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, trusted subordinate's cold type of pain, colic of cold type.

Herba Ephedrae: nature and flavor: pungent, micro-hardship, temperature.Gui Jing: enter lung, urinary bladder channel.Diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.

Radix Aconiti: nature and flavor: pungent, heat, poisonous.Gui Jing: enter spleen, the gate of vitality, hands faint the moon, shaoyin channel.Dispelling cold and dampness, loose ailment said due to cold or exposure, warming the meridian, pain relieving.Control anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, the diseases such as hemiplegia.

Squama Manis: salty, is slightly cold.Return liver, stomach warp.Effect, invigorate blood circulation Xiao Disorder, stimulates the menstrual flow, stimulating milk secretion, detumescence and apocenosis.Cure mainly for, amenorrhea, lump in the abdomen, rheumatic arthralgia, paralysis due to windstroke, carbuncle, scrofula.

Radix Aconiti Lateralis Preparata: nature and flavor: Xin Gan, heat, poisonous.Gui Jing: enter the heart, spleen, kidney channel.Recuperating depleted YANG mends fire, dispelling cold and removing dampness.For excessive YIN keeping YANG externally, the splenic diarrhea cold-dysentery, anemofrigid-damp arthralgia.This medicated wine adopts the Radix Aconiti Lateralis Preparata concocted through salt, Radix Glycyrrhizae, bean.

Ligamentum cervi: nature and flavor: light, micro-salty, temperature.Wind-damp dispelling, bone and muscle strengthening.For rheumatic arthritis, brothers are unable, sural spasm.

Cortex Acanthopancis: nature and flavor: pungent, temperature.Gui Jing: enter liver, kidney channel.Wind-damp dispelling, strengthening bone and muscle, blood circulation promoting and blood stasis dispelling, the kidney invigorating bone strengthening.Control anemofrigid-damp arthralgia, muscles and bones contraction is anxious, lumbago, the diseases such as traumatic injury impairment caused by overstrain.

60 ° of pure jowar wines: pungent, sweet, warm; GUIXIN, liver, stomach through resisting cold gas, row medicine gesture; Invigorate blood circulation, dissipating blood stasis, removing toxic substances.Be mainly used in molten and all medicines, disengage active ingredient in medicine.Using 60 ° of pure Sorghum vulgare Pers. Wines as drawing envoy, under strong temperature effect, impel that full presciption medicine thing is molten to be integrated.

Brown sugar: warm in nature, sweet in the mouth, enter spleen, effect and the effects beneficial gas of brown sugar are enriched blood, spleen invigorating warming the stomach, slow in pain relieving, activating blood circulation to dissipate blood stasis etc.

In sum, the Rhizoma Et Radix Notopterygii in formula of the present invention, Radix Angelicae Pubescentis, Radix Saposhnikoviae, Herba Ephedrae, Cortex schizophragmatis integrifolii radicis and Herba Aristolochiae Mollissimae eliminating evil to reach the object of taking stopgap measures; Radix Rehmanniae Preparata, Ligamentum cervi, Squama Manis, Niu Xi, Rhizoma Homalomenae and Cortex Acanthopancis invigorating the liver and kidney, wind-damp dispelling is to reach the object of effecting a permanent cure; Radix Aconiti, Radix Aconiti Kusnezoffii, Ramulus Cinnamomi, Herba Ephedrae, Radix Saposhnikoviae and the logical battalion of Cortex Cinnamomi a surname defend, and wind-damp dispelling is good by Persistent Pain; Radix Aconiti Lateralis Preparata and Herba Lycopodii warming YANG are invigorated blood circulation; Radix Clematidis invigorating the liver and kidney, strengthening bone and muscle, wind-damp dispelling; To enrich blood dredging collateral cold expelling for drawing with brown sugar and wine, all medicines share, monarch, and to reach wind-damp dispelling, stopping numbness pain, liver and kidney tonifying, strengthening bone and muscle, effect that logical battalion defends, reaches therapeutic purposes.

toxicity test

The all crude drug of the present invention select the Chinese crude drug of high-quality before preparation, through thoroughly cleaning, remove impurity, the medicated wine made is harmless to human body, but as and the same use of other medicines, then can cause damage to the person, must be noted that for this reason following some:

Still do not lose the function of wine after the preparation of 1, wine and medicine, take barbiturates central nervous depressant after taking medicated wine again and can cause serious CNS inhibition.Obvious CNS inhibition is just caused when the wine drinking moderate also takes the barbiturate of narcotic dosage simultaneously time, make the respond of patient low, judging and analysis ability decline, occur significantly calm and hypnotic effect, can cause stupor surprisingly as strengthened consumption again.

2, psychosis chlorpromazine, promethazine, perphenazine, stable, chlordiazepoxide and Claritin chlorphenamine, match heptan, steep, stupid extra large Lamine etc. was as use same with wine, also has coordinate repression, gently then make people go into a coma sleepy to nervus centralis; Heavy then make human blood pressure drop low, produce stupor, even occur respiration inhibition and dead.

3, when taking oxidase inhibitor, in human body, therefore the activity of multiple enzyme can be suppressed.Now drinking medicated wine can make the acetaldehyde concentration in blood increase because the enzyme system of its decomposing alcohol is suppressed, causes the acetaldehyde poisoning, occurs the reactions such as Nausea and vomiting, headache, blood pressure drops.Ethanol also has induction to increase the effect of medicament decomposes enzyme, can make shorten the action time of anticoagulant.

4, ethanol has inhibitory action to thrombin, can make non-tip vasodilation, so, should not can not take with anticoagulant simultaneously.

5, the induction of drug enzyme effect of ethanol can make rifampicin decompose quickening, strengthens the toxicity of liver; The decomposition of the medicine such as phenytoin Sodium, aminophenazone also can be made to accelerate, thus reduce the effect of medicine.

6, diabetes patient's period in a medicine should not be drunk, because a small amount of wine can make drug metabolizing enzyme secretion increasing, makes hypoglycemic drug insulin, and the curative effect of the medicines such as glyburide reduces, so that does not reach therapeutic effect.If heavy drinking can suppress the secretion of drug metabolizing enzyme in liver, the effect of antidiabetic drug is strengthened, causes serious hypoglycemic reaction, death of even going into a coma.

7, Patients with Cardiovascular/Cerebrovascular Diseases is taken medicine appropriate to the occasion alleviating alcohol addiction, in order to avoid there is serious untoward reaction.Take the patient of nitroglycerin, if heavy drinking can cause gastrointestinal upset, blood pressure drops, even can faint.

If 8, hyperpietic takes depressor or furosemide, the acidum ethacrynicums such as second buttocks, Aiselazine.The diuretic such as chlortalidone, all can cause postural hypotension.Then react even more serious when taking pargyline, there will be Nausea and vomiting, uncomfortable in chest, dyspnea etc., even there will be hypertensive crisis.

9, drinking the toxic and side effects that can increase and bring out multi-medicament as excessive, can there is alcoholic hepatitis in alcoholic, talking endlessly cry of certain animals containing the synthesis of interference choline, increasing the weight of hepatic injury, glutamate pyruvate transaminase is raised, causing stupor and respiration inhibition as taken chloromethane again.

10, ethanol and aspirin can suppress gastric secretion, increase epithelial cell shedding, and destroy the barrier action of gastric mucosa to acid, resistance vitamin K is in the effect of liver, stop the formation of thrombinogen in liver, causing bleeding property gastritis, impels gastrorrhagia aggravate or cause the serious consequences such as gastric perforation.

11, wine and sulfa drugs are with using the Psychotoxicity that can strengthen ethanol.Griseofulvin and wine are together with then easily occurring mood disorders and nervous symptoms.The same use of the digitalis preparation such as wine and digoxin, can reduce the effect of concentration of blood kalium because of ethanol; Human body is made to strengthen the sensitivity of Folium Digitalis Purpureae medicine and cause poisoning.

In a word, drink medicated wine, suitable then use, should not then prohibit.Consumption will be drunk on request or follow the doctor's advice simultaneously, must guard against the indiscriminate drink of drink.

good effect of the present invention is:

1, medicated wine, ancient title " medicated wine ".Be the important component part of motherland's medical science pharmacology of Chinese medical formulae, Ye Shi motherland traditional medicine is prevented and cured diseases another unique medical method.Have " make simple, be convenient to deposit, easy to use, inside and outsidely availablely, inexpensive save time, safe and reliable, instant effect, curative effect is high." feature, the adopter that thus takes like a shot is increasing, dark in doubly liking; This medicated wine prescription is rigorous, and law is strict and impartial.The product of compatibility channels sootheing and network vessel quickening, eliminating stagnation repercussive, make that mechanism of qi is logical, stasis loose and arthralgia pain from disappearing; The product of compatibility righting QI invigorating, nourishing kidney bone strengthening, make heresy dispel and just not hinder.Therefore, this medicated wine is for the rheumatic joint disease such as migratory arthralgia, arthralgia aggravated by cold for the treatment of caused by wind, cold, wet, and clinical efficacy is distinguished especially, and has no side effect and untoward reaction.

2, simply, patent medicine cost is low for formula of the present invention and preparation technology, is applicable to rural area, shortage of medical services and medicines crowd in mountain area uses; The present invention has good effect, instant effect, easy to use, the feature of compatibility safety non-toxic.

3, the patient of arthralgia, rheumatic and rheumatoid, muscular soreness, very wide in whole nation distribution, particularly mountain area, upper level, three provinces in the northeast of China's cold district and southern damp-heat area are more serious.About this type of patient of the whole nation estimates about there are 5,000 ten thousand people, the present invention is through nearly thousand routine clinical verifications for a long time, and effective percentage accounts for more than 98%.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is described in further detail.

embodiment 1

Be used for the treatment of a production method for the medicated wine of arthralgia, be made up of following steps:

The first step, raw material of Chinese medicine Radix Rehmanniae Preparata 15g, the Rhizoma Et Radix Notopterygii 9g of select, Ramulus Cinnamomi 9g, Herba Aristolochiae Mollissimae 9g, Radix Angelicae Pubescentis 9g, Radix Saposhnikoviae 9g, Herba Lycopodii 9g, Rhizoma Homalomenae 9g, Radix Clematidis 9g, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 9g, Radix Aconiti Kusnezoffii 6g, Radix Achyranthis Bidentatae 6g, Cortex Cinnamomi 6g, Herba Ephedrae 6g, Radix Aconiti 6g, Squama Manis 5g, Radix Aconiti Lateralis Preparata 3g, Ligamentum cervi 3g, Cortex Acanthopancis 12g carried out screen by formula, clean, dry, pulverize, mix as coarser powder crude drug, be made as A material, for subsequent use;

Second step, by formula consumption, the A of first step material is put in marmite and added clean cold water, add water to and exceed raw material powder 20 centimetres, soaks after 7 hours, decoction;

3rd step, first with big fire be heated to boiling after, use little fire instead, maintain boil to 60 minutes, cross filtrate; Add water appropriate, then decoct, filter, repeatedly twice, merges three filtrates, heating, then adds brown sugar 750g, and limit heating, limit are stirred, and is made as B and expects;

4th step, the 3rd step B material to be left standstill after 8 hours, get supernatant heating and be condensed into paste, after cooling, then add 60 ° of pure jowar wine 1500g and mix after sealing deposits three months in rearmounted hermetic container, get supernatant, be finished product.

embodiment 2

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight:

Radix Rehmanniae Preparata 10g, Rhizoma Et Radix Notopterygii 5g, Ramulus Cinnamomi 59g, Herba Aristolochiae Mollissimae 5g, Radix Angelicae Pubescentis 5g, Radix Saposhnikoviae 5g, Herba Lycopodii 5g, Rhizoma Homalomenae 5g, Radix Clematidis 5g, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 5g, Radix Aconiti Kusnezoffii 2g, Radix Achyranthis Bidentatae 2g, Cortex Cinnamomi 2g, Herba Ephedrae 2g, Radix Aconiti 2g, Squama Manis 1g, Radix Aconiti Lateralis Preparata 1g, Ligamentum cervi 1g, Cortex Acanthopancis 5g, 60 ° of pure jowar wine wine 1000g and brown sugar 700g.

The production method of this embodiment is with embodiment one.

embodiment 3

Be used for the treatment of a medicated wine for arthralgia, it is formed by the preparation of raw material of following weight:

Radix Rehmanniae Preparata 20g, Rhizoma Et Radix Notopterygii 15g, Ramulus Cinnamomi 15g, Herba Aristolochiae Mollissimae 15g, Radix Angelicae Pubescentis 15g, Radix Saposhnikoviae 15g, Herba Lycopodii 15g, Rhizoma Homalomenae 15g, Radix Clematidis 15g, Cortex Illicii (Cortex schizophragmatis integrifolii radicis) 15g, Radix Aconiti Kusnezoffii 10g, Radix Achyranthis Bidentatae 10g, Cortex Cinnamomi 10g, Herba Ephedrae 10g, Radix Aconiti 10g, Squama Manis 10g, Radix Aconiti Lateralis Preparata 8g, Ligamentum cervi 8g, Cortex Acanthopancis 20g, 60 ° of pure jowar wine 2000g and brown sugar 800g.

The production method of this embodiment is with embodiment one.

Instructions of taking of the present invention is: every day early, evening is each once, each 30 ~ 50g, and each course for the treatment of is 20 days; Should note when taking: 1. can not intersect with other medicated wine and drink; 2. can not with barbiturates central nervous depressant with using; 3. can not use together with psychosis and Claritin; 4. can not with anticoagulant with using; 5. can not with sulfonamides with using; 6. diabetes, hypertension, cardiovascular disease, gastric ulcer, hepatitis patient are cautious use of; 7. child and anemia of pregnant woman's forbidding; 8. weak and sickly old people is cautious use of.

The patient of arthralgia, rheumatic and rheumatoid, muscular soreness, very wide in whole nation distribution, particularly mountain area, upper level, three provinces in the northeast of China's cold district and southern damp-heat area are more serious.About this type of patient of the whole nation estimates about there are 5,000 ten thousand people, the special medicinal liquor of our development, through long-term thousands of routine clinical verification, effective percentage accounts for more than 98%, below enumerates ten routine model cases as follows:

model case

Case 1: Liu's ××, man, 44 years old, mausoleum, Qixian County mouth village people, occupation: peasant, because dried up storehouse is comparatively near, often lower water fishing, suffered from rheumatic arthritis more than 15 years, in April, 2012 to June, and after taking two courses for the treatment of of this medicated wine, symptom disappears completely.

Case 2: recklessly ××, female, 57 years old, the yellow hole village people in Qixian County, occupation: mountain area teachers, two leg joints inflammation were had a surplus for 10 years, and after drinking two courses for the treatment of of this medicated wine in May, 2012, symptom disappears completely.

Case 3: king's ××, female, 43 years old, the positive village people in north, Qixian County, occupation: self-employed businessman, membra arthralgia, lumbago be more than 3 years, and after drinking this medicated wine one course for the treatment of in March, 2013, symptom disappears completely.

Case 4: Liu's ××, female, 63 years old, virtuous village people was defended in Xunxian, occupation: peasant, suffered from rheumatic and rheumatoid arthralgia more than 20 year, and after drinking three courses for the treatment of of this medicated wine in April, 2013 to June, pain disappears completely.

Case 5: ××, man, 58 years old, virtuous village people was defended in Xunxian, occupation: peasant, and leg joint pain is more than 2 years, and drink a course for the treatment of of this medicated wine in October, 2013, pain disappears completely.

Case 6: Wei ××, man, 65 years old, Jun Xianxin people from town, occupation: peasant, once served in army, suffered from lumbago and skelalgia more than 20 year, drank two courses for the treatment of of this medicated wine in April, 2014 to June, and pain disappears.

Case 7: recklessly ××, female, 37 years old, the positive village people in north, Qixian County, occupation: peasant, suffered from cold when giving birth to a child and causes arthralgia more than 10 year, and drink two courses for the treatment of of this medicated wine in June, 2014 to August, pain disappears substantially.

Case 8: Lee's ××, man, 26 years old, the positive village people in north, Qixian County, occupation: workman, suffer from scapulohumeral periarthritis nearly a year, in May, 2014 drinks this medicated wine 10 days, and symptom obviously alleviates.

Case 9: suddenly ×, man, 52 years old, virtuous village people was defended in Xunxian, occupation: peasant, and lumbago is more than 8 years, and drink a course for the treatment of of this medicated wine in June, 2014, symptom alleviates.

Case 10: high mountain ××, man, 56 years old, Qixian County bridge alliance village people, occupation: peasant, waist suffered from hyperosteogeny more than 2 years, and drink a course for the treatment of of this medicated wine in June, 2014, pain symptom alleviates.

Claims (6)

1. be used for the treatment of a medicated wine for arthralgia, it is characterized in that: it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 10 ~ 20 parts, Rhizoma Et Radix Notopterygii 5 ~ 15 parts, Ramulus Cinnamomi 5 ~ 15 parts, Herba Aristolochiae Mollissimae 5 ~ 15 parts, Radix Angelicae Pubescentis 5 ~ 15 parts, Radix Saposhnikoviae 5 ~ 15 parts, Herba Lycopodii 5 ~ 15 parts, Rhizoma Homalomenae 5 ~ 15 parts, Radix Clematidis 5 ~ 15 parts, Cortex Illicii another name Cortex schizophragmatis integrifolii radicis 5 ~ 15 parts, Radix Aconiti Kusnezoffii 2 ~ 10 parts, Radix Achyranthis Bidentatae 2 ~ 10 parts, Cortex Cinnamomi 2 ~ 10 parts, 2 ~ 10 parts, Herba Ephedrae, Radix Aconiti 2 ~ 10 parts, Squama Manis 1 ~ 10 part, Radix Aconiti Lateralis Preparata 1 ~ 8 part, Ligamentum cervi 1 ~ 8 part, Cortex Acanthopancis 5 ~ 20 parts, wine 1000 ~ 2000 parts and 700 ~ 800 parts, brown sugar.

2. a kind of medicated wine being used for the treatment of arthralgia according to claim 1, is characterized in that: it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 10 parts, Rhizoma Et Radix Notopterygii 5 parts, Ramulus Cinnamomi 5 parts, Herba Aristolochiae Mollissimae 5 parts, Radix Angelicae Pubescentis 5 parts, Radix Saposhnikoviae 5 parts, Herba Lycopodii 5 parts, Rhizoma Homalomenae 5 parts, Radix Clematidis 5 parts, Cortex Illicii another name Cortex schizophragmatis integrifolii radicis 5 parts, Radix Aconiti Kusnezoffii 2 parts, Radix Achyranthis Bidentatae 2 parts, Cortex Cinnamomi 2 parts, 2 parts, Herba Ephedrae, Radix Aconiti 2 parts, Squama Manis 1 part, Radix Aconiti Lateralis Preparata 1 part, Ligamentum cervi 1 part, Cortex Acanthopancis 5 parts, wine 1000 parts and 700 parts, brown sugar.

3. a kind of medicated wine being used for the treatment of arthralgia according to claim 1, is characterized in that: it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 15 parts, Rhizoma Et Radix Notopterygii 9 parts, Ramulus Cinnamomi 9 parts, Herba Aristolochiae Mollissimae 9 parts, Radix Angelicae Pubescentis 9 parts, Radix Saposhnikoviae 9 parts, Herba Lycopodii 9 parts, Rhizoma Homalomenae 9 parts, Radix Clematidis 9 parts, Cortex Illicii another name Cortex schizophragmatis integrifolii radicis 9 parts, Radix Aconiti Kusnezoffii 6 parts, Radix Achyranthis Bidentatae 6 parts, Cortex Cinnamomi 6 parts, 6 parts, Herba Ephedrae, Radix Aconiti 6 parts, Squama Manis 5 parts, Radix Aconiti Lateralis Preparata 3 parts, Ligamentum cervi 3 parts, Cortex Acanthopancis 12 parts, wine 1500 parts and 750 parts, brown sugar.

4. a kind of medicated wine being used for the treatment of arthralgia according to claim 1, is characterized in that: it is formed by the preparation of raw material of following weight parts:

Radix Rehmanniae Preparata 20 parts, Rhizoma Et Radix Notopterygii 15 parts, Ramulus Cinnamomi 15 parts, Herba Aristolochiae Mollissimae 15 parts, Radix Angelicae Pubescentis 15 parts, Radix Saposhnikoviae 15 parts, Herba Lycopodii 15 parts, Rhizoma Homalomenae 15 parts, Radix Clematidis 15 parts, Cortex Illicii another name Cortex schizophragmatis integrifolii radicis 15 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Achyranthis Bidentatae 10 parts, Cortex Cinnamomi 10 parts, 10 parts, Herba Ephedrae, Radix Aconiti 10 parts, Squama Manis 10 parts, Radix Aconiti Lateralis Preparata 8 parts, Ligamentum cervi 8 parts, Cortex Acanthopancis 20 parts, wine 2000 parts and 800 parts, brown sugar.

5. a kind of medicated wine being used for the treatment of arthralgia according to claim 1, is characterized in that: described wine is 60 ° of pure jowar wines.

6. a kind of production method being used for the treatment of the medicated wine of arthralgia according to claim 1, is characterized in that, be made up of following steps:

The first step, by the raw material of Chinese medicine Radix Rehmanniae Preparata 10 ~ 20 part of formula by select, Rhizoma Et Radix Notopterygii 5 ~ 15 parts, Ramulus Cinnamomi 5 ~ 15 parts, Herba Aristolochiae Mollissimae 5 ~ 15 parts, Radix Angelicae Pubescentis 5 ~ 15 parts, Radix Saposhnikoviae 5 ~ 15 parts, Herba Lycopodii 5 ~ 15 parts, Rhizoma Homalomenae 5 ~ 15 parts, Radix Clematidis 5 ~ 15 parts, Cortex Illicii another name Cortex schizophragmatis integrifolii radicis 5 ~ 15 parts, Radix Aconiti Kusnezoffii 2 ~ 10 parts, Radix Achyranthis Bidentatae 2 ~ 10 parts, Cortex Cinnamomi 2 ~ 10 parts, 2 ~ 10 parts, Herba Ephedrae, Radix Aconiti 2 ~ 10 parts, Squama Manis 1 ~ 10 part, Radix Aconiti Lateralis Preparata 1 ~ 8 part, Ligamentum cervi 1 ~ 8 part, Cortex Acanthopancis 5 ~ 20 parts screens, cleaning, dry, pulverize, mixing is coarser powder crude drug, be made as A material, for subsequent use,

Second step, by formula consumption by the A of the first step material put in marmite, add clean cold water, add water to and exceed raw material powder 20 centimetres, soaks after 7 hours, decoction;

3rd step, be first heated to boiling with big fire after, use little fire instead, maintain and boil to 60 minutes, cross filtrate, add water appropriate, then decoct, filter, repeatedly twice, merges three filtrates, heating, then adds 700 ~ 800 parts, brown sugar, and limit heating, limit are stirred, and is made as B and expects;

4th step, the 3rd step B material to be left standstill after 8 hours, get supernatant heating and be condensed into paste, after cooling, then add 60 ° of pure jowar wines 1000 ~ 2000 parts, mix after sealing deposits three months in rearmounted hermetic container, get supernatant, be finished product.