CN104173712A - Traditional Chinese medicine composition for relieving uneasiness and supplementing qi after operation and preparation method thereof - Google Patents
Traditional Chinese medicine composition for relieving uneasiness and supplementing qi after operation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for relieving uneasiness and supplementing qi after operation and a preparation method thereof. The traditional Chinese medicine composition for relieving uneasiness and supplementing qi after operation comprises the following materials: benzoin, lily bulb, cypraeae concha, catharanthus roseus, medulla junci, cecidien, flos albizzia, choerospondias axillaris, Edgeworthia chrysantha Lindl., oenanthe stolonifera, Swertia bifolia Batal, cactus, elm leaves, panax quinquefolium, stigma croci, rhodiola henryi, husked sorghum, yam, alpiniae oxyphyllae fructus, longan aril, rigescent hawksbeard root, lotus seed and wild panax pseudo-ginseng, and further comprises the following auxiliary materials: traditional Chinese medicine nutrient composite powder, bee honey and water soluble vitamin. The preparation method comprises the steps of extracting the effective ingredients of the raw materials to be prepared into extract powder, and preparing the extract powder together with the auxiliary materials into corresponding preparation formulations according to conventional pharmaceutical processes. The traditional Chinese medicine composition disclosed by the invention has a reasonable formula with the materials supplementing each other, has the effects of tranquilizing and allaying excitement, nourishing blood and supplementing qi, strengthening the spleen and replenishing qi, treating consumptive diseases, strengthening the waist and knees, strengthening the liver and stomach, replenishing essence and blood, strengthening tendons and muscles and nourishing heart and easing mind, enhances the immune function of bodies, has a remarkable treatment effect, and is especially suitable for patients of postoperative recovery.
Description
Technical field
The present invention relates to technical field of Chinese medicines, especially relate to Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves and preparation method thereof.
Background technology
Operation is a lot of main treatment meanss of disease clinically, losing blood all can appear in general operation, postoperative have that heating, infection, metabolism disorder, loss of appetite, digestive and absorptive functions decline, are hard and dry, malaise, and the symptoms such as poor sleep, severe complication even occurs.And sufficient high-quality sleep is one of assurance of postoperative physical recovery, insomnia is the postoperative problem often facing, and according to clinical data, finds, after operation, especially, in 2 days, insomnia incidence rate is up to more than 90%.
After operation, occurring the phenomenon of insomnia, may be because the pain of bringing after operation causes, in the time of especially at night, if the sensation of pain is obvious, will cause patient to have a rest; May be because patient's factor at heart causes on the other hand, be exactly influential to patient's health originally after operation, adds the wound of soul, and a lot of patient at heart pressure will become very large, so also easily cause the phenomenon of insomnia to occur.
The major function of sleep is to promote spirit and physical recovery, and insomnia declines patient's immunity of organisms, and endocrine dysfunction postpones the edge of a knife and wound healing, so will cause enough attention for the postoperative insomnia of patient.
From clinical practice, a lot of patients occur that insomnia situation is, all can take the medicine of some Anshen Bunaos, help sleep.These medicines, for slight insomnia crowd, have and take effect, but need to adopt the stable medicine that waits for the insomnia of severe slightly, and this class medicine can not long-term taking, and this class of long-term taking has compared with major injury health, and produces drug dependence.
Summary of the invention
For the problem of above-mentioned existence, technical problem solved by the invention is just to provide the Chinese medicine composition and preparation method thereof of the postoperative QI invigorating of calming the nerves of a kind of invigorating the spleen and benefiting QI, tonifying liver and stomach, benefiting essence-blood, strengthening bone and muscle, tranquilizing by nourishing the heart.
Technical scheme of the present invention is:
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, comprises the crude drug of following weight portion: 60～150 parts of Benzoinumes, 30～100 portions of Bulbus Liliies, 50～80 parts of shellfish teeth, 20～60 portions of Herba Catharanthi Roseis, 50～80 portions of Medulla Juncies, 140～190 parts of Galla Turcica (Galla Helepensis)s, 130～170 parts of Flos Albiziaes, 60～110 parts of Fructus Choerospondiatis, 70～150 parts of Flos edgeworthiae, 40～80 parts of Herba Apiis, 48～70 parts of Herba Swertiae heteranthaes, 55～85 parts of Radix et Caulis Opuntiae Dilleniis, 40～60 parts of Folium ulmi pumilaves, 56～90 parts of Radix Panacis Quinquefoliis, 30～90 parts of Stigma Crocis, 45～85 portions of Semen Pisi sativis seven.
Further, the Chinese medicine composition of the described a kind of postoperative QI invigorating of calming the nerves, also comprises the adjuvant of following weight portion: 30～85 parts of Chinese medicine nutrition composite powders, 30～60 parts of Mel, 0.5～0.7 part of water soluble vitamins.
Further, described Chinese medicine nutrition composite powder is comprised of following medical material: 29～45 portions of Sorghum vulgare Pers.s, 15～30 portions of Rhizoma Dioscoreaes, 10～29 parts of Fructus Alpiniae Oxyphyllae, 10～15 portions of Arillus Longans, 14～20 parts of Crepis crocea Babc.(C.turczaninowii C.A.Mey.)s, 18～26 parts of Semen Nelumbinis, 1～9 part of wild Radix Notoginseng.
Further, the preparation method of described Chinese medicine nutrition composite powder is:
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 120～200 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieves, and merges the fine powder after all sieving.
Further, the mixture that described water soluble vitamins is comprised of vitamin B1, vitamin B2, vitamin C, the ratio between each composition is: 1:3:4.Vitamin B1 can keep circulation, digestion, nerve and intramuscular normal function; Adjust gastrointestinal function; Form the coenzyme of decarboxylase, participate in sugared metabolism; Vitamin B2 is the constituent of many important coenzyme classes in body, and these enzymes transmit hydrogen in substance metabolism process in vivo, it or protein, sugar, fatty acid metabolism and energy utilization and the necessary material of composition; Vitamin C increases antibody, builds up resistance.
A preparation method for the Chinese medicine composition of the postoperative QI invigorating of calming the nerves, its step is as follows:
Step 1: raw medicinal material extracts active ingredients
(1) get the raw materials ready: by described proportioning, take respectively Benzoinum, Bulbus Lilii, shellfish tooth, Herba Catharanthi Rosei, Medulla Junci, Galla Turcica (Galla Helepensis), Flos Albiziae, Fructus Choerospondiatis, Flos edgeworthiae, Herba Apii, Herba Swertiae heteranthae, Radix et Caulis Opuntiae Dillenii, Folium ulmi pumilae, Radix Panacis Quinquefolii, Stigma Croci, Semen Pisi sativi seven, with mobile tap water, clean up, dry standby;
(2) pretreatment: above-mentioned medical material is mixed, use with respect to the pure tap water that mixes 10～12 times of amounts of medical material and soak, soak time is 3～5 hours, after complete wetting, first microwave treatment, more ultrasonic helping carried; Wherein the ultrasonic supersonic frequency of carrying that helps is 80～150khz, and temperature is 70～80 ℃, and the time is 0.5～1.5 hour, and the ultrasonic extracting method that helps can reduce extraction time, improves extracting efficiency;
(3) decoct and extract: the pretreated medical material of step (2) is positioned in boiler together with the water that soaks medical material, after big fire is boiled, turn little fire and decoct extraction 2～3 times, each extraction time is 0.5～1 hour, stirs 2～3 times in leaching process, filter, merge decoction liquor;
(4) concentrate drying: the decoction liquor that step (3) is made is condensed into thick paste, dry with spray dryer spraying, make extract powder, standby; Spraying rate of drying is fast, and feed liquid is long-pending through atomization rear surface to be increased greatly, and in hot-air flow, moment just can be evaporated 95%～98% moisture content, completes and only needs the several seconds drying time, after being dried, does not need to pulverize and screening, reduces production process, improves product purity.
Step 2: Chinese medicine nutrition composite powder preparation
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, 120～200 orders sieve, the coarse powder that can not sieve is pulverized again, repeatedly sieve, merge the fine powder after all sieving, take 30～85 parts of gained fine powders, obtain Chinese medicine nutrition composite powder.
Step 3: combination pharmacy
The extract powder that step 1 is made mixes with described adjuvant, according to the technique of various dosage forms and adjuvant, requires to make corresponding dosage form.Described adjuvant comprises binding agent, filler, lubricant etc., and described dosage form comprises granule, pill etc.
Further, in described step 1, the microwave power of microwave treatment is 500～600w, and the time is 5～10 minutes.Under microwave treatment, the fragmentation due to mutual high-speed motion and friction of crude drug cell tissue, the cell solution of bursting is overflowed content, thereby improves the extraction ratio of medical material.
The invention has the beneficial effects as follows: compatibility of drugs of the present invention rationally, select medicine to forbid, all medicines share, bring out the best in each other, effect is remarkable.The combination of medicine of the present invention all has more comprehensive rehabilitation and health-care effect to human body, its effect is comprehensive, can calm the nerves calmness, hemostatic analgesia, the QI invigorating that nourishes blood, invigorating the spleen and benefiting QI, control labor void, strong waist knee joint, tonifying liver and stomach, benefiting essence-blood, strengthening bone and muscle, tranquilizing by nourishing the heart, the immunologic function of enhancing body, significantly improve the postoperative mental status of patient, promote patient's spirit and physical recovery.
The specific embodiment
Embodiment 1:
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, comprises the crude drug of following weight portion: 60 parts of Benzoinumes, 30 portions of Bulbus Liliies, 50 parts of shellfish teeth, 20 portions of Herba Catharanthi Roseis, 50 portions of Medulla Juncies, 140 parts of Galla Turcica (Galla Helepensis)s, 130 parts of Flos Albiziaes, 60 parts of Fructus Choerospondiatis, 70 parts of Flos edgeworthiae, 40 parts of Herba Apiis, 48 parts of Herba Swertiae heteranthaes, 55 parts of Radix et Caulis Opuntiae Dilleniis, 40 parts of Folium ulmi pumilaves, 56 parts of Radix Panacis Quinquefoliis, 30 parts of Stigma Crocis, 45 portions of Semen Pisi sativis seven; The adjuvant that also comprises following weight portion: 30 parts of Chinese medicine nutrition composite powders, 30 parts of Mel, 0.5 part of water soluble vitamins.
Wherein, described Chinese medicine nutrition composite powder is comprised of following medical material: 29 portions of Sorghum vulgare Pers.s, 15 portions of Rhizoma Dioscoreaes, 10 parts of Fructus Alpiniae Oxyphyllae, 10 portions of Arillus Longans, 14 parts of Crepis crocea Babc.(C.turczaninowii C.A.Mey.)s, 18 parts of Semen Nelumbinis, 1 part of wild Radix Notoginseng.The mixture that described water soluble vitamins is comprised of vitamin B1, vitamin B2, vitamin C, the ratio between each composition is: 1:3:4.Vitamin B1 can keep circulation, digestion, nerve and intramuscular normal function; Adjust gastrointestinal function; Form the coenzyme of decarboxylase, participate in sugared metabolism; Vitamin B2 is the constituent of many important coenzyme classes in body, and these enzymes transmit hydrogen in substance metabolism process in vivo, it or protein, sugar, fatty acid metabolism and energy utilization and the necessary material of composition; Vitamin C increases antibody, builds up resistance.
The preparation method of described Chinese medicine nutrition composite powder is:
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 120 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieves, and merges the fine powder after all sieving.
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, the preparation method of its granule is as follows:
Step 1: raw medicinal material extracts active ingredients
(1) get the raw materials ready: by described proportioning, take respectively Benzoinum, Bulbus Lilii, shellfish tooth, Herba Catharanthi Rosei, Medulla Junci, Galla Turcica (Galla Helepensis), Flos Albiziae, Fructus Choerospondiatis, Flos edgeworthiae, Herba Apii, Herba Swertiae heteranthae, Radix et Caulis Opuntiae Dillenii, Folium ulmi pumilae, Radix Panacis Quinquefolii, Stigma Croci, Semen Pisi sativi seven, with mobile tap water, clean up, dry standby;
(2) pretreatment: above-mentioned medical material is mixed, use with respect to the pure tap water that mixes 10 times of amounts of medical material and soak, soak time is 3 hours, after complete wetting, and first microwave treatment, the microwave power of described microwave treatment is 500w, time is 5 minutes, and under microwave treatment, crude drug cell tissue is due to mutual high-speed motion and friction and fragmentation, the routed solution of cell is overflowed content, thereby improves the extraction ratio of medical material; Ultrasonic helping carried again, and wherein the ultrasonic supersonic frequency of carrying that helps is 80khz, and temperature is 70 ℃, and the time is 0.5 hour, and the ultrasonic extracting method that helps can reduce extraction time, improves extracting efficiency;
(3) decoct and extract: the pretreated medical material of step (2) is positioned in boiler together with the water that soaks medical material, after big fire is boiled, turn little fire and decoct extraction 2 times, each extraction time is 0.5 hour, stirs 2 times in leaching process, filter, merge decoction liquor;
(4) concentrate drying: the decoction liquor that step (3) is made is condensed into thick paste, dry with spray dryer spraying, make extract powder, standby; Spraying rate of drying is fast, and feed liquid is long-pending through atomization rear surface to be increased greatly, and in hot-air flow, moment just can be evaporated 95% moisture content, completes and only needs the several seconds drying time, after being dried, does not need to pulverize and screening, reduces production process, improves product purity.
Step 2: Chinese medicine nutrition composite powder preparation
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 120 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieve, merge the fine powder after all sieving, take 30 parts of gained fine powders, obtain Chinese medicine nutrition composite powder.
Step 3: combination pharmacy
The extract powder that step 1 is made mixes with described adjuvant, then adds 25 parts of lactose, 90 parts of starch slurries, 2 parts of Polyethylene Glycol, granulation agent.Wherein, lactose is as filler, and starch slurry is as binding agent, and Polyethylene Glycol is as lubricant.
Embodiment 2:
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, comprises the crude drug of following weight portion: 105 parts of Benzoinumes, 65 portions of Bulbus Liliies, 65 parts of shellfish teeth, 40 portions of Herba Catharanthi Roseis, 65 portions of Medulla Juncies, 165 parts of Galla Turcica (Galla Helepensis)s, 150 parts of Flos Albiziaes, 85 parts of Fructus Choerospondiatis, 110 parts of Flos edgeworthiae, 60 parts of Herba Apiis, 59 parts of Herba Swertiae heteranthaes, 70 parts of Radix et Caulis Opuntiae Dilleniis, 50 parts of Folium ulmi pumilaves, 73 parts of Radix Panacis Quinquefoliis, 60 parts of Stigma Crocis, 65 portions of Semen Pisi sativis seven; The adjuvant that also comprises following weight portion: 57.5 parts of Chinese medicine nutrition composite powders, 45 parts of Mel, 0.6 part of water soluble vitamins.
Wherein, described Chinese medicine nutrition composite powder is comprised of following medical material: 37 portions of Sorghum vulgare Pers.s, 22.5 portions of Rhizoma Dioscoreaes, 19.5 parts of Fructus Alpiniae Oxyphyllae, 12.5 portions of Arillus Longans, 17 parts of Crepis crocea Babc.(C.turczaninowii C.A.Mey.)s, 22 parts of Semen Nelumbinis, 5 parts of wild Radix Notoginseng.The mixture that described water soluble vitamins is comprised of vitamin B1, vitamin B2, vitamin C, the ratio between each composition is: 1:3:4.Vitamin B1 can keep circulation, digestion, nerve and intramuscular normal function; Adjust gastrointestinal function; Form the coenzyme of decarboxylase, participate in sugared metabolism; Vitamin B2 is the constituent of many important coenzyme classes in body, and these enzymes transmit hydrogen in substance metabolism process in vivo, it or protein, sugar, fatty acid metabolism and energy utilization and the necessary material of composition; Vitamin C increases antibody, builds up resistance.
The preparation method of described Chinese medicine nutrition composite powder is:
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 160 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieves, and merges the fine powder after all sieving.
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, the preparation method of its granule is as follows:
Step 1: raw medicinal material extracts active ingredients
(1) get the raw materials ready: by described proportioning, take respectively Benzoinum, Bulbus Lilii, shellfish tooth, Herba Catharanthi Rosei, Medulla Junci, Galla Turcica (Galla Helepensis), Flos Albiziae, Fructus Choerospondiatis, Flos edgeworthiae, Herba Apii, Herba Swertiae heteranthae, Radix et Caulis Opuntiae Dillenii, Folium ulmi pumilae, Radix Panacis Quinquefolii, Stigma Croci, Semen Pisi sativi seven, with mobile tap water, clean up, dry standby;
(2) pretreatment: above-mentioned medical material is mixed, use with respect to the pure tap water that mixes 11 times of amounts of medical material and soak, soak time is 4 hours, after complete wetting, and first microwave treatment, the microwave power of described microwave treatment is 550w, time is 7.5 minutes, and under microwave treatment, crude drug cell tissue is due to mutual high-speed motion and friction and fragmentation, the routed solution of cell is overflowed content, thereby improves the extraction ratio of medical material; Ultrasonic helping carried again, and wherein the ultrasonic supersonic frequency of carrying that helps is 115khz, and temperature is 75 ℃, and the time is 1.0 hours, and the ultrasonic extracting method that helps can reduce extraction time, improves extracting efficiency;
(3) decoct and extract: the pretreated medical material of step (2) is positioned in boiler together with the water that soaks medical material, after big fire is boiled, turn little fire and decoct extraction 3 times, each extraction time is 0.75 hour, stirs 3 times in leaching process, filter, merge decoction liquor;
(4) concentrate drying: the decoction liquor that step (3) is made is condensed into thick paste, dry with spray dryer spraying, make extract powder, standby; Spraying rate of drying is fast, and feed liquid is long-pending through atomization rear surface to be increased greatly, and in hot-air flow, moment just can be evaporated 96.5% moisture content, completes and only needs the several seconds drying time, after being dried, does not need to pulverize and screening, reduces production process, improves product purity.
Step 2: Chinese medicine nutrition composite powder preparation
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 160 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieve, merge the fine powder after all sieving, take 57.5 parts of gained fine powders, obtain Chinese medicine nutrition composite powder.
Step 3: combination pharmacy
The extract powder that step 1 is made mixes with described adjuvant, then adds 35 parts of lactose, 105 parts of starch slurries, 4.5 parts of Polyethylene Glycol, granulation agent.Wherein, lactose is as filler, and starch slurry is as binding agent, and Polyethylene Glycol is as lubricant.
Embodiment 3:
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, comprises the crude drug of following weight portion: 150 parts of Benzoinumes, 100 portions of Bulbus Liliies, 80 parts of shellfish teeth, 60 portions of Herba Catharanthi Roseis, 80 portions of Medulla Juncies, 190 parts of Galla Turcica (Galla Helepensis)s, 170 parts of Flos Albiziaes, 110 parts of Fructus Choerospondiatis, 150 parts of Flos edgeworthiae, 80 parts of Herba Apiis, 70 parts of Herba Swertiae heteranthaes, 85 parts of Radix et Caulis Opuntiae Dilleniis, 60 parts of Folium ulmi pumilaves, 90 parts of Radix Panacis Quinquefoliis, 90 parts of Stigma Crocis, 85 portions of Semen Pisi sativis seven; The adjuvant that also comprises following weight portion: 85 parts of Chinese medicine nutrition composite powders, 60 parts of Mel, 0.7 part of water soluble vitamins.
Wherein, described Chinese medicine nutrition composite powder is comprised of following medical material: 45 portions of Sorghum vulgare Pers.s, 30 portions of Rhizoma Dioscoreaes, 29 parts of Fructus Alpiniae Oxyphyllae, 15 portions of Arillus Longans, 20 parts of Crepis crocea Babc.(C.turczaninowii C.A.Mey.)s, 26 parts of Semen Nelumbinis, 9 parts of wild Radix Notoginseng.The mixture that described water soluble vitamins is comprised of vitamin B1, vitamin B2, vitamin C, the ratio between each composition is: 1:3:4.Vitamin B1 can keep circulation, digestion, nerve and intramuscular normal function; Adjust gastrointestinal function; Form the coenzyme of decarboxylase, participate in sugared metabolism; Vitamin B2 is the constituent of many important coenzyme classes in body, and these enzymes transmit hydrogen in substance metabolism process in vivo, it or protein, sugar, fatty acid metabolism and energy utilization and the necessary material of composition; Vitamin C increases antibody, builds up resistance.
The preparation method of described Chinese medicine nutrition composite powder is:
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 200 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieves, and merges the fine powder after all sieving.
A Chinese medicine composition for the postoperative QI invigorating of calming the nerves, the preparation method of its pill is as follows:
Step 1: raw medicinal material extracts active ingredients
(1) get the raw materials ready: by described proportioning, take respectively Benzoinum, Bulbus Lilii, shellfish tooth, Herba Catharanthi Rosei, Medulla Junci, Galla Turcica (Galla Helepensis), Flos Albiziae, Fructus Choerospondiatis, Flos edgeworthiae, Herba Apii, Herba Swertiae heteranthae, Radix et Caulis Opuntiae Dillenii, Folium ulmi pumilae, Radix Panacis Quinquefolii, Stigma Croci, Semen Pisi sativi seven, with mobile tap water, clean up, dry standby;
(2) pretreatment: above-mentioned medical material is mixed, use with respect to the pure tap water that mixes 12 times of amounts of medical material and soak, soak time is 5 hours, after complete wetting, and first microwave treatment, the microwave power of described microwave treatment is 600w, time is 10 minutes, and under microwave treatment, crude drug cell tissue is due to mutual high-speed motion and friction and fragmentation, the routed solution of cell is overflowed content, thereby improves the extraction ratio of medical material; Ultrasonic helping carried again, and wherein the ultrasonic supersonic frequency of carrying that helps is 150khz, and temperature is 80 ℃, and the time is 1.5 hours, and the ultrasonic extracting method that helps can reduce extraction time, improves extracting efficiency;
(3) decoct and extract: the pretreated medical material of step (2) is positioned in boiler together with the water that soaks medical material, after big fire is boiled, turn little fire and decoct extraction 3 times, each extraction time is 1 hour, stirs 3 times in leaching process, filter, merge decoction liquor;
(4) concentrate drying: the decoction liquor that step (3) is made is condensed into thick paste, dry with spray dryer spraying, make extract powder, standby; Spraying rate of drying is fast, and feed liquid is long-pending through atomization rear surface to be increased greatly, and in hot-air flow, moment just can be evaporated 98% moisture content, completes and only needs the several seconds drying time, after being dried, does not need to pulverize and screening, reduces production process, improves product purity.
Step 2: Chinese medicine nutrition composite powder preparation
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, with mobile tap water, clean up, In Shade dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done, have contained cooling;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are put respectively and in exsiccator, blotted to without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 200 orders sieve, and the coarse powder that can not sieve is pulverized again, repeatedly sieve, merge the fine powder after all sieving, take 85 parts of gained fine powders, obtain Chinese medicine nutrition composite powder.
Step 3: combination pharmacy
The extract powder that step 1 is made mixes with described Chinese medicine nutrition composite powder, water soluble vitamins, Mel is heated to 122 ℃, the goods that occur larger rufous bubble, water content is below 10%, relative density is 14, then adds 0.13 part of CMC～Na as disintegrating agent, with the full-automatic speed control Chinese medicinal pills preparing machine of YUJ～16A, makes small honey pill, dry, polishing and get final product.
Typical case:
Case one: Xu certain, man, 37 years old, because the left lower limb of traffic accident is pulverized, does amputation.After operation, because of pain, and spirit gets a hard knock, excited, short-tempered, irritability, and poor appetite, sleeps bad, and wound resume speed is extremely slow.Start to take Chinese medicine composition of the present invention after 3 days, sleep stable gradually, continue to take Chinese medicine composition of the present invention after 6 days, the mental status is good, and it is large that appetite becomes, and it is good that wound recovers.
Case two: beam, female, 29 years old, because of severe loss of blood in puerperal, complexion is poor, weak all over, sleep disorder is steady, and malaise started to take Chinese medicine composition of the present invention after 3 days, sleep stable gradually, continue to take Chinese medicine composition of the present invention after 6 days, complexion takes a turn for the better to some extent, after 10 days, can leave the bed and walk about, take a walk, health is strong gradually.
Case three: grandson, female, 65 years old, after cerebral surgery operation, often insomnia, absentminded, weakness of the spleen and stomach, inappetence.Start to take Chinese medicine composition of the present invention after 2 days, insomnia makes moderate progress, and continues to take Chinese medicine composition of the present invention after 4 days, gather colour, and it is large that appetite becomes, after 6 days, sleep and stable, it is good that the state of an illness is recovered.
Claims (7)
1. a Chinese medicine composition for the postoperative QI invigorating of calming the nerves, is characterized in that comprising the crude drug of following weight portion: 60～150 parts of Benzoinumes, 30～100 portions of Bulbus Liliies, 50～80 parts of shellfish teeth, 20～60 portions of Herba Catharanthi Roseis, 50～80 portions of Medulla Juncies, 140～190 parts of Galla Turcica (Galla Helepensis)s, 130～170 parts of Flos Albiziaes, 60～110 parts of Fructus Choerospondiatis, 70～150 parts of Flos edgeworthiae, 40～80 parts of Herba Apiis, 48～70 parts of Herba Swertiae heteranthaes, 55～85 parts of Radix et Caulis Opuntiae Dilleniis, 40～60 parts of Folium ulmi pumilaves, 56～90 parts of Radix Panacis Quinquefoliis, 30～90 parts of Stigma Crocis, 45～85 portions of Semen Pisi sativis seven.
2. the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves according to claim 1, characterized by further comprising the adjuvant of following weight portion: 30～85 parts of Chinese medicine nutrition composite powders, 30～60 parts of Mel, 0.5～0.7 part of water soluble vitamins.
3. the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves according to claim 2, is characterized in that described Chinese medicine nutrition composite powder is comprised of following medical material: 29～45 portions of Sorghum vulgare Pers.s, 15～30 portions of Rhizoma Dioscoreaes, 10～29 parts of Fructus Alpiniae Oxyphyllae, 10～15 portions of Arillus Longans, 14～20 parts of Crepis crocea Babc.(C.turczaninowii C.A.Mey.)s, 18～26 parts of Semen Nelumbinis, 1～9 part of wild Radix Notoginseng.
4. the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves according to claim 3, is characterized in that the preparation method of described Chinese medicine nutrition composite powder is:
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, clean up, dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are dried to respectively without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 120～200 orders sieve.
5. the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves according to claim 2, is characterized in that the mixture that described water soluble vitamins is comprised of vitamin B1, vitamin B2, vitamin C, and the ratio between each composition is: 1:3:4.
6. according to the preparation method of the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves described in claim 1～5 any one, it is characterized in that step is as follows:
Step 1: raw medicinal material extracts active ingredients
(1) get the raw materials ready: by described proportioning, take respectively Benzoinum, Bulbus Lilii, shellfish tooth, Herba Catharanthi Rosei, Medulla Junci, Galla Turcica (Galla Helepensis), Flos Albiziae, Fructus Choerospondiatis, Flos edgeworthiae, Herba Apii, Herba Swertiae heteranthae, Radix et Caulis Opuntiae Dillenii, Folium ulmi pumilae, Radix Panacis Quinquefolii, Stigma Croci, Semen Pisi sativi seven, clean up, dry standby;
(2) pretreatment: above-mentioned medical material is mixed, use with respect to the pure tap water that mixes 10～12 times of amounts of medical material and soak, first microwave treatment, more ultrasonic helping carried;
(3) decoct and extract: the pretreated medical material of step (2) is positioned in boiler together with the water that soaks medical material, and heating decocts extracts 2～3 times, and each extraction time is 0.5～1 hour, filters, and merges decoction liquor;
(4) concentrate drying: the decoction liquor that step (3) is made is condensed into thick paste, spraying is dry, makes extract powder, standby;
Step 2: Chinese medicine nutrition composite powder preparation
(1) get the raw materials ready: by described proportioning, take respectively Sorghum vulgare Pers., Rhizoma Dioscoreae, Fructus Alpiniae Oxyphyllae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng, clean up, dry standby;
(2) parch: Sorghum vulgare Pers., Fructus Alpiniae Oxyphyllae are placed in respectively to the slow stir-fry of iron pan low baking temperature to well-done;
(3) drying: Rhizoma Dioscoreae, Arillus Longan, Crepis crocea Babc.(C.turczaninowii C.A.Mey.), Semen Nelumbinis, wild Radix Notoginseng are dried to respectively without moisture;
(4) grind into powder: all medical materials that step (2) and step (3) are made are put into pulverizer and are ground into fine powder, and 120～200 orders sieve, and take 30～85 parts of gained fine powders, obtain Chinese medicine nutrition composite powder.
Step 3: combination pharmacy
The extract powder that step 1 is made mixes with described adjuvant, according to the technique of various dosage forms and adjuvant, requires to make corresponding dosage form.
7. the preparation method of the Chinese medicine composition of a kind of postoperative QI invigorating of calming the nerves according to claim 6, the microwave power that it is characterized in that microwave treatment in step 1 is 500～600w, the time is 5～10 minutes.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104771560A (en) * | 2015-04-29 | 2015-07-15 | 李福军 | Medicine for treating mania |
| CN104825869A (en) * | 2015-04-29 | 2015-08-12 | 李福军 | Drug for treating anxiety |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623298A (en) * | 2013-12-11 | 2014-03-12 | 山东省立医院 | Medicine for promoting postoperative recovery of breast cancer |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103623298A (en) * | 2013-12-11 | 2014-03-12 | 山东省立医院 | Medicine for promoting postoperative recovery of breast cancer |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104771560A (en) * | 2015-04-29 | 2015-07-15 | 李福军 | Medicine for treating mania |
| CN104825869A (en) * | 2015-04-29 | 2015-08-12 | 李福军 | Drug for treating anxiety |
| CN104771560B (en) * | 2015-04-29 | 2016-04-06 | 郑素娟 | A kind of medicine for the treatment of mania |
| CN104825869B (en) * | 2015-04-29 | 2016-04-06 | 郑素娟 | A kind of medicine for the treatment of anxiety neurosis |
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Application publication date: 20141203 |