CN104173213A - Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture - Google Patents
Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture Download PDFInfo
- Publication number
- CN104173213A CN104173213A CN201410309974.8A CN201410309974A CN104173213A CN 104173213 A CN104173213 A CN 104173213A CN 201410309974 A CN201410309974 A CN 201410309974A CN 104173213 A CN104173213 A CN 104173213A
- Authority
- CN
- China
- Prior art keywords
- moisture
- skin moisture
- extract
- keeping composition
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 32
- 102000010637 Aquaporins Human genes 0.000 claims abstract description 14
- 108010063290 Aquaporins Proteins 0.000 claims abstract description 14
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 10
- 239000011707 mineral Substances 0.000 claims abstract description 10
- 159000000000 sodium salts Chemical class 0.000 claims abstract description 9
- 239000003921 oil Substances 0.000 claims description 19
- 239000000284 extract Substances 0.000 claims description 18
- 238000005516 engineering process Methods 0.000 claims description 12
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims description 9
- 235000010755 mineral Nutrition 0.000 claims description 9
- 239000001540 sodium lactate Substances 0.000 claims description 9
- 229940005581 sodium lactate Drugs 0.000 claims description 9
- 235000011088 sodium lactate Nutrition 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 8
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 6
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 6
- 239000012752 auxiliary agent Substances 0.000 claims description 5
- 239000003974 emollient agent Substances 0.000 claims description 5
- 239000003995 emulsifying agent Substances 0.000 claims description 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 5
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical group [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 4
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 4
- 241000907663 Siproeta stelenes Species 0.000 claims description 4
- -1 dimethyl siloxane Chemical class 0.000 claims description 4
- 125000005456 glyceride group Chemical group 0.000 claims description 4
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims description 4
- LIKBJVNGSGBSGK-UHFFFAOYSA-N iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[Fe+3].[Fe+3] LIKBJVNGSGBSGK-UHFFFAOYSA-N 0.000 claims description 4
- 229940119170 jojoba wax Drugs 0.000 claims description 4
- 229910052748 manganese Inorganic materials 0.000 claims description 4
- 239000011572 manganese Substances 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical group [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 4
- CRPCXAMJWCDHFM-UHFFFAOYSA-M sodium;5-oxopyrrolidine-2-carboxylate Chemical compound [Na+].[O-]C(=O)C1CCC(=O)N1 CRPCXAMJWCDHFM-UHFFFAOYSA-M 0.000 claims description 4
- 229910000010 zinc carbonate Inorganic materials 0.000 claims description 4
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 3
- 229940032094 squalane Drugs 0.000 claims description 3
- 150000005846 sugar alcohols Polymers 0.000 claims description 3
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
- 230000002421 anti-septic effect Effects 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 229940060184 oil ingredients Drugs 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 45
- 238000012360 testing method Methods 0.000 description 13
- 230000003020 moisturizing effect Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 239000006071 cream Substances 0.000 description 6
- 239000004909 Moisturizer Substances 0.000 description 5
- 230000001815 facial effect Effects 0.000 description 5
- 230000001333 moisturizer Effects 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 4
- 210000002615 epidermis Anatomy 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 3
- 230000037394 skin elasticity Effects 0.000 description 3
- 206010012442 Dermatitis contact Diseases 0.000 description 2
- 235000021355 Stearic acid Nutrition 0.000 description 2
- 235000018936 Vitellaria paradoxa Nutrition 0.000 description 2
- 241001135917 Vitellaria paradoxa Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 208000002029 allergic contact dermatitis Diseases 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 229940057910 shea butter Drugs 0.000 description 2
- 238000010583 slow cooling Methods 0.000 description 2
- 239000008117 stearic acid Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- LKDRXBCSQODPBY-AMVSKUEXSA-N L-(-)-Sorbose Chemical compound OCC1(O)OC[C@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-AMVSKUEXSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000006101 laboratory sample Substances 0.000 description 1
- 229940001447 lactate Drugs 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 229940042472 mineral oil Drugs 0.000 description 1
- 235000014593 oils and fats Nutrition 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 210000004003 subcutaneous fat Anatomy 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention provides a moistening composition capable of balancing skin moisture and a preparation process of the moistening composition capable of balancing skin moisture. The composition comprises the following components in percentage by mass: 0.01-10 percent of organic sodium salt, 0.01-10 percent of mineral complex and 0.01-10 percent of aquaporins. The preparation process comprises the following steps: preparing an aqueous phase; preparing an oil phase; mixing oil and water; and adding adjuvant. By means of the synergetic effect of multiple components, the moistening composition is capable of maintaining a moistening state of skin and promoting the health condition of the skin.
Description
[technical field]
The present invention relates to daily cosmetics field, particularly the moisture-keeping composition of balance skin moisture and preparation technology thereof.
[background technology]
Skin divides epidermis, corium and subcutaneous fat.The outermost layer of epidermis is horny layer, water suction, barrier function due to horny layer itself, and contained nature moisturizing factor and the effect of the material such as amino acids, lactate and saccharide in horny layer, make horny layer keep certain water content, maintain the moistening of skin.The outward appearance of skin is relevant with cuticular moisture, and normal keratodermatitis contains the moisture of 10-30% conventionally, to maintain softness and the elasticity of skin.The growth at age and the impact of extraneous undesirable element all can cause keratodermatitis moisture to decline, when the moisture of keratodermatitis is lower than 10% time, skin just there will be the situations such as dry, tight, coarse and desquamation, and forms dry stricture of vagina, causes many skin problems.Wetting agent in skin care item can help keratodermatitis absorb the moisture in skin and effectively pin moisture, reaches the effect of skin beauty water profit.
The skin care item with moisture-keeping efficacy on market are a lot, mainly contain following several situation:
1, oils and fats moisturizing: this class moisturizer can not be absorbed by the skin, it forms moisturizing barrier one on skin, makes the moisture of skin be difficult for evaporation, scatter and disappear, and protection skin is not invaded by foreign object; But these class skin care item are too greasy, are only suitable for extremely dry skin or use in bone-dry winter.
2, moisture-absorbing moisture-keeping: this class moisturizer is most typical is exactly polyalcohols, conventional is glycerol, sorbose, propylene glycol, Polyethylene Glycol etc.This class material has the function absorbing water from surrounding, fine to the moistening effect of skin under the high condition of relative humidity; But in very low at relative humidity, cold dry and windy weather, not only skin is not had to benefit, can absorb water from skin inner layer on the contrary, and make skin drier, cutaneous normal function.
3, hydration moisturizing: this class moisturizer has hydrophilic, it can form a net that can pin free water, and the free water that makes to appear skin becomes and in conjunction with water, is difficult for evaporation and scatters and disappears, thereby reaches moistening effect; Yet for the dry crowd of skin quality, moistening effect is limited.
4, repair moisturizing: this class moisturizer is often added various vitamin, to improve defencive function and the moisture-keeping functions of skin itself, reaches more preferably effect.
In market, product moisture-keeping efficacy is relatively single, or these moisturizing simple combination.Therefore, be necessary to provide a kind of new moisturizer.
[summary of the invention]
Main purpose of the present invention is to provide a kind of moisture-keeping composition and preparation technology thereof of balance skin moisture.
The present invention is achieved through the following technical solutions above-mentioned purpose: a kind of moisture-keeping composition of balance skin moisture, comprise water and organic solvent, also comprise Organic Sodium Salt, 0.01-10% mineral complex and the 0.01-10% aquaporin of quality accounting 0.01-10%.
In some embodiments, described Organic Sodium Salt is the mixture of sodium lactate or sodium lactate and PCA-Na.
In some embodiments, described mineral complex is one or more in Sepitonic M3, Sepitonic M4, bloodstone extract, malachite extract, manganese spar extract, smithsonite extract.
In some embodiments, described aquaporin is one or more in Aquaxyl, Aquaregul K, Aquaporin.
Preferably, its Organic Sodium Salt that comprises quality accounting 0.1-1%, 0.05-2% mineral complex and 0.1-5% aquaporin.
A moisture-keeping composition preparation technology for balance skin moisture, comprises the steps:
(a) according to following mass ratio modulation water:
Constant temperature 10min after water is stirred and heated to 90-95 ℃;
(b) according to following mass ratio modulation oil phase:
Excipient 2.1-2.4
Emulsifying agent 3.3-4.9
Emollient 7.9-16
Oil phase is stirred and heated to 85-90 ℃;
(c) oil phase slowly poured into water and stirred, after adding, homogenizing 5min forms mixed liquor, then makes mixed liquor naturally cool to 40-45 ℃;
(d) mixed liquor adds following auxiliary agent under in stirring:
To in mixed liquor, stir until mixed liquor is cooled to room temperature.
In some embodiments, the dihydroxylic alcohols that described polyhydric alcohol is C3-C4 or trihydroxylic alcohol, described thickening agent be HANSHENGJIAO, card ripple in one or both, described wetting agent is hyaluronate sodium, described stabilizing agent is EDTA-2Na.
In some embodiments, described excipient is one or both in hexadecanol and octadecanol, described emulsifying agent is one or more in monostearate list glyceride, Eumulgin BA25, Emulgade PL68/50, Emulgade 165, and described emollient is one or more in newborn fruit tree oil, Jojoba oil, squalane, hydrogenated polydecene, dimethyl siloxane, caprylic/capric triglyceride.
In some embodiments, described antiseptic is Euxyl PE 9010, and described pH nertralizer is triethanolamine.
In some embodiments, described Organic Sodium Salt is the mixture of sodium lactate or sodium lactate and PCA-Na, described mineral complex is one or more in Sepitonic M3, Sepitonic M4, bloodstone extract, malachite extract, manganese spar extract, smithsonite extract, and described aquaporin is one or more in Aquaxyl, Aquaregul K, Aquaporin.
Compared with prior art, the moisture-keeping composition of balance skin moisture of the present invention and preparation technology's beneficial effect are:
1, under the synergism of Multiple components, balance skin electrolyte, the immunity of increase skin, improves skin harmful substance and ultraviolet defence capability to external world, and the health status of the multiple skin of Yan, improves skin resistivity, strengthens skin elasticity.
2, sodium lactate can form hydration shell with other chemical analysis and prevent from moisture of skin volatilization from making skin in light moisture state for cosmetics, prevents that wrinkle from producing, and can produce synergy while being combined with other skin whitener.
3, the mineral complex in compositions has the skin elasticity of enhancing and moisture-keeping efficacy, can promote the absorption of other active component in formula and effectively utilize.
4, aquaporin acts on epidermal area, by promoting water cycle, plays instant and long-acting moistening effect.
[accompanying drawing explanation]
Fig. 1 is that the embodiment of the present invention 2 moisturizing essence are used controlled trial epidermis moisture to scheme over time.
[specific embodiment]
A moisture-keeping composition preparation technology for balance skin moisture, comprises the steps:
(a) according to following mass ratio modulation water:
Constant temperature 10min after water is stirred and heated to 90-95 ℃;
(b) according to following mass ratio modulation oil phase:
Excipient 2.1-2.4
Emulsifying agent 3.3-4.9
Emollient 7.9-16
Oil phase is stirred and heated to 85-90 ℃;
(c) oil phase slowly poured into water and stirred, after adding, homogenizing 5min forms mixed liquor, then makes mixed liquor naturally cool to 40-45 ℃;
(d) mixed liquor adds following auxiliary agent under in stirring:
To in mixed liquor, stir until mixed liquor is cooled to room temperature
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1: moisturizing face cream
The present embodiment moisturizing face cream is comprised of the raw material of following weight proportion:
A) water:
B) oil phase:
C) auxiliary agent:
Preparation method: water, glycerol, butanediol, EDTA-2Na, hyaluronate sodium, HANSHENGJIAO and Ka Bo 934 are mixed and disperse to obtain water; Again hexadecanol, octadecanol, stearic acid list glyceride, BA 25, Emulgade PL68/50, shea butter, hydrogenated polydecene, Jojoba oil, caprylic/capric triglyceride and dimethyl siloxane are mixed to get to oil phase; Water is heated to 90 ℃, and keeps 10min, oil phase is heated to 85 ℃, more slowly pour oil phase into water, rapid stirring, is used homogenizer to carry out homogenizing processing after all adding, homogenizing 5min, afterwards slow cooling to 40 ℃ simultaneously; Finally adjuvant component is added successively, regulate pH remain on 6.2～7.0 between all can, continue to be stirred to completely cooling, discharging and get final product.
Method of testing: select 30 tested volunteers, 35～50 years old age, without serious systemic disease, without cosmetic allergic contact dermatitis history.
Embodiment 1 product is used in to the left side face after clean face every day, sooner or later respectively once; Right side facial skin is used placebo (same recipe, containing marine extracts active ingredient) as a comparison.
Test result: after 3 months, according to service condition, observe and experimenter's reflection arrangement test result, as shown in table 1, finer and smoother moistening before most experimenter's skin is used, the water humidity of left side face skin has clear improvement compared with contrast position, right side, and without any anaphylaxis, prove that Application Example 1 facial cream can effectively improve the appearance that face is dry, reduce microgroove, has the effect of Glycerin, maintenance skin elasticity.
Table 1
| Number | Effective | Effectively | Generally | Invalid |
| 30 people | 20 people | 6 people | 3 people | 1 people |
Embodiment 2: moisturizing essence
The present embodiment moisture saver mask is comprised of the raw material of following weight proportion:
A) water:
B) oil phase:
C) auxiliary agent
Preparation method: water, propylene glycol, butanediol, EDTA-2Na, hyaluronate sodium and HANSHENGJIAO are mixed and disperseed to obtain water; Again hexadecanol, stearic acid list glyceride, Emulgade PL68/50, Emulgade 165, shea butter, Jojoba oil, squalane, mineral oil and dimethyl siloxane are mixed to get to oil phase; Water is heated to 90 ℃, and keeps 10min, oil phase is heated to 85 ℃, more slowly pour oil phase into water, rapid stirring, is used homogenizer to carry out homogenizing processing after all adding, homogenizing 5min, afterwards slow cooling to 40 ℃ simultaneously; Finally adjuvant component is added successively, continue to be stirred to completely cooling, discharging and get final product.
Method of testing: select 20 tested volunteers, 28～45 years old age, without serious systemic disease, without cosmetic allergic contact dermatitis history.
Test adopts Comeometer CM 825 (CK Electronic GmbH) moisture of skin tester.Test environment temperature is 25 ℃, and relative humidity (RH) is 60%, and before measuring, 10min exposes tested position, allows examinee quiet down in this environment simultaneously.On the forearm of left and right, respectively mark the square Experimental Area of 3.5cm * 3.5cm, and Experimental Area is numbered, left arm is as the test zone of embodiment 2 skin protection facial creams, and the symmetrical region of right arm is as the test zone of blank (same recipe, containing marine extracts active ingredient).First use alkaline fancy soap to clean test position, after rinsing well, dry.Before test sample application, use Comeometer CM 825 skinanalysis apparatus to measure tested position moisture.Get 0.1g laboratory sample and be applied to tested position, on skin, evenly smear 2min, when 10min, 40min, 60min, 120min and 180min, use Comeometer CM 825 testers to measure, test out moisture content in skin value (its linear module represents with a.u.), and record test result, in tested region, choose 10 points and measure, and to record mean values be single test.
Test result: as Fig. 1, test result shows that experimenter uses numerical value that the epidermis moisture of embodiment 2 skin protection facial creams improves apparently higher than blank group, and characterizing embodiment 2 skin protection facial creams is to have obvious moistening effect.
Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, without departing from the concept of the premise of the invention, can also make some distortion and improvement, these all belong to protection scope of the present invention.
Claims (10)
1. a moisture-keeping composition for balance skin moisture, comprises water and organic solvent, it is characterized in that: it also comprises Organic Sodium Salt, 0.01-10% mineral complex and the 0.01-10% aquaporin of quality accounting 0.01-10%.
2. the moisture-keeping composition of balance skin moisture according to claim 1, is characterized in that: described Organic Sodium Salt is the mixture of sodium lactate or sodium lactate and PCA-Na.
3. the moisture-keeping composition of balance skin moisture according to claim 1, is characterized in that: described mineral complex is one or more in Sepitonic M3, Sepitonic M4, bloodstone extract, malachite extract, manganese spar extract, smithsonite extract.
4. the moisture-keeping composition of balance skin moisture according to claim 1, is characterized in that: described aquaporin is one or more in Aquaxyl, Aquaregul K, Aquaporin.
5. the moisture-keeping composition of balance skin moisture according to claim 1, is characterized in that: its Organic Sodium Salt that comprises quality accounting 0.1-1%, 0.05-2% mineral complex and 0.1-5% aquaporin.
6. a moisture-keeping composition preparation technology for balance skin moisture, is characterized in that comprising the steps:
(a) according to following mass ratio modulation water:
Constant temperature 10min after water is stirred and heated to 90-95 ℃;
(b) according to following mass ratio modulation oil phase:
Excipient 2.1-2.4
Emulsifying agent 3.3-4.9
Emollient 7.9-16
Oil phase is stirred and heated to 85-90 ℃;
(c) oil phase slowly poured into water and stirred, after adding, homogenizing 5min forms mixed liquor, then makes mixed liquor naturally cool to 40-45 ℃;
(d) mixed liquor adds following auxiliary agent under in stirring:
To in mixed liquor, stir until mixed liquor is cooled to room temperature.
7. the moisture-keeping composition preparation technology of balance skin moisture according to claim 6, it is characterized in that: the dihydroxylic alcohols that described polyhydric alcohol is C3-C4 or trihydroxylic alcohol, described thickening agent be HANSHENGJIAO, card ripple in one or both, described wetting agent is hyaluronate sodium, and described stabilizing agent is EDTA-2Na.
8. the moisture-keeping composition preparation technology of balance skin moisture according to claim 6, it is characterized in that: described excipient is one or both in hexadecanol and octadecanol, described emulsifying agent is one or more in monostearate list glyceride, Eumulgin BA25, Emulgade PL68/50, Emulgade165, and described emollient is one or more in newborn fruit tree oil, Jojoba oil, squalane, hydrogenated polydecene, dimethyl siloxane, caprylic/capric triglyceride.
9. the moisture-keeping composition preparation technology of balance skin moisture according to claim 6, is characterized in that: described antiseptic is Euxyl PE9010, and described pH nertralizer is triethanolamine.
10. the moisture-keeping composition preparation technology of balance skin moisture according to claim 6, it is characterized in that: described Organic Sodium Salt is the mixture of sodium lactate or sodium lactate and PCA-Na, described mineral complex is one or more in Sepitonic M3, Sepitonic M4, bloodstone extract, malachite extract, manganese spar extract, smithsonite extract, and described aquaporin is one or more in Aquaxyl, Aquaregul K, Aquaporin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410309974.8A CN104173213A (en) | 2014-07-01 | 2014-07-01 | Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410309974.8A CN104173213A (en) | 2014-07-01 | 2014-07-01 | Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104173213A true CN104173213A (en) | 2014-12-03 |
Family
ID=51954747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410309974.8A Pending CN104173213A (en) | 2014-07-01 | 2014-07-01 | Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104173213A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958222A (en) * | 2015-07-20 | 2015-10-07 | 广州三十六度伴生物科技有限公司 | Glacier solid water |
| CN106038369A (en) * | 2016-06-27 | 2016-10-26 | 广州岚萃贸易有限公司 | Formula of malachite and white tea refreshing base |
| WO2017103936A1 (en) * | 2015-12-16 | 2017-06-22 | Avshalomov Mattityahu | Skin care preparations for babies |
| CN109125115A (en) * | 2018-09-25 | 2019-01-04 | 广州艾蓓生物科技有限公司 | A kind of element face is spraying and preparation method thereof |
| KR20190036341A (en) * | 2017-09-27 | 2019-04-04 | (주)아모레퍼시픽 | Cosmetic Composition for Reducing Stickiness and Improving Transparency of Emulsion Formulation |
| CN109953908A (en) * | 2019-03-13 | 2019-07-02 | 广州莱倩化妆品有限公司 | A kind of formula and preparation method thereof of essence cream |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2948285A1 (en) * | 2009-07-27 | 2011-01-28 | Seppic Sa | OIL-IN-WATER EMULSION WITH IMPROVED SENSORY PROPERTIES |
| CN101453979B (en) * | 2006-04-27 | 2013-01-16 | 拜埃尔斯多尔夫股份公司 | Cosmetic preparation containing aquaporin stimulator and uses thereof |
| CN103027859A (en) * | 2011-09-29 | 2013-04-10 | 北京奥唯康健生物科技有限公司 | Cosmetic containing Ganoderma capense glycopeptides, and its application |
-
2014
- 2014-07-01 CN CN201410309974.8A patent/CN104173213A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101453979B (en) * | 2006-04-27 | 2013-01-16 | 拜埃尔斯多尔夫股份公司 | Cosmetic preparation containing aquaporin stimulator and uses thereof |
| FR2948285A1 (en) * | 2009-07-27 | 2011-01-28 | Seppic Sa | OIL-IN-WATER EMULSION WITH IMPROVED SENSORY PROPERTIES |
| CN103027859A (en) * | 2011-09-29 | 2013-04-10 | 北京奥唯康健生物科技有限公司 | Cosmetic containing Ganoderma capense glycopeptides, and its application |
Non-Patent Citations (7)
| Title |
|---|
| SEPPIC: "AQUAXYL", 《WWW.SEPPIC.COM/FILE/GALLERYELEMENT/PJ/48/BB/21/23/2484EAQUAXYLLEAFLETGBSEPTEMBER2412536540329328273.PDF》 * |
| SEPPIC: "MOISTURIZING MIST", 《WWW.SEPPIC.COM/FILE/GALLERYELEMENT/PJ/50/16/A0/15/3260_SEPITONIC_M3_ENERGETIC_BATTERY_GB_MARCH_7688445272467787406.PDF》 * |
| SOLABIA GROUP: "Aquaregul-k", 《WWW.SOLABIA.COM/SOLABIA/PRODUITS.NSF/SW_PROD/DA140948B4161F17C1257489002DA7A3?OPENDOCUMENT》 * |
| 我爱你的眼睛: "乳酸钠", 《WWW.BAIKE.COM/WIKDOC/SP/QR/HISTORY/VERSION.DO?VER=35&HISIDEN=MY31,0,AGFZZWCEEVVJENJRBQ》 * |
| 朱文元等: "《美容皮肤医学新进展》", 31 March 2009, 化学工业出版社 * |
| 穆守元: "国内外乳酸及其衍生品的应用和市场前景", 《化工技术经济》 * |
| 阎世翔: "《化妆品科学（下）》", 31 October 1998, 科学技术文献出版社 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958222A (en) * | 2015-07-20 | 2015-10-07 | 广州三十六度伴生物科技有限公司 | Glacier solid water |
| WO2017103936A1 (en) * | 2015-12-16 | 2017-06-22 | Avshalomov Mattityahu | Skin care preparations for babies |
| CN108778240A (en) * | 2015-12-16 | 2018-11-09 | 阿甫夏洛穆·夫马修 | baby skin care |
| US11571373B2 (en) | 2015-12-16 | 2023-02-07 | Mattityahu AVSHALOMOV | Skin care preparations for babies |
| IL260028B1 (en) * | 2015-12-16 | 2023-06-01 | Mattityahu Avshalomov | Skin care preparations for babies |
| IL260028B2 (en) * | 2015-12-16 | 2023-10-01 | Mattityahu Avshalomov | Baby care products |
| CN106038369A (en) * | 2016-06-27 | 2016-10-26 | 广州岚萃贸易有限公司 | Formula of malachite and white tea refreshing base |
| KR20190036341A (en) * | 2017-09-27 | 2019-04-04 | (주)아모레퍼시픽 | Cosmetic Composition for Reducing Stickiness and Improving Transparency of Emulsion Formulation |
| KR102359729B1 (en) | 2017-09-27 | 2022-02-09 | (주)아모레퍼시픽 | Cosmetic Composition for Reducing Stickiness and Improving Transparency of Emulsion Formulation |
| CN109125115A (en) * | 2018-09-25 | 2019-01-04 | 广州艾蓓生物科技有限公司 | A kind of element face is spraying and preparation method thereof |
| CN109125115B (en) * | 2018-09-25 | 2021-04-16 | 广州艾蓓生物科技有限公司 | Face-beautifying spray and preparation method thereof |
| CN109953908A (en) * | 2019-03-13 | 2019-07-02 | 广州莱倩化妆品有限公司 | A kind of formula and preparation method thereof of essence cream |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104173213A (en) | Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture | |
| WO2015135313A1 (en) | Borojo skin care product and use thereof for natural moisturizing, anti-ageing, anti-uv, anti-anaphylaxis and whitening | |
| CN104856928A (en) | Anti-wrinkle and anti-aging cosmetic and preparation method thereof | |
| CN109157453A (en) | A kind of pro-skin slow releasing composition and its cosmetics | |
| CN107007492A (en) | A kind of makeup remover and preparation method thereof | |
| CN108542870B (en) | Mild soothing infant face cream | |
| CN107184506A (en) | It is for baby to prevent chapped antifreeze frost and preparation method thereof | |
| CN108969446A (en) | It is a kind of enhance skin barrier function infant prevent chapped skin care compositions and preparation method thereof | |
| CN104434768A (en) | Moisturizing lotion with slow-release efficacy and preparation method of moisturizing lotion | |
| CN110575412A (en) | a special skin caring liquid for pore containing medicinal extract of Fomitopsis pinicola layer, and its preparation method | |
| CN107007513A (en) | Topical composition and skin cleaning mask with dispel blackhead and pore refining effect | |
| CN106619337A (en) | Crowfoot crack resistant cream for infants and a preparing method thereof | |
| CN107137760A (en) | A kind of moisturizing maintenance dressing and preparation method thereof | |
| CN103340798B (en) | Natural plant sun cream and preparation process thereof | |
| CN109350591A (en) | A kind of U.S. face dried noodle film and preparation method thereof | |
| CN109528540A (en) | A kind of eye essence composition of mild anti-aging | |
| CN102614103A (en) | Middle and old-aged nourishing and wrinkle-resisting cream and preparation method thereof | |
| CN114306165A (en) | Moisturizing composition and preparation method thereof | |
| CN107802553A (en) | Moisturizing and anti-allergy emulsion and preparation method and application thereof | |
| CN108434046A (en) | A kind of moisture-keeping cosmetics composition and moisturiser | |
| CN116850074A (en) | Soothing and moisturizing skin care milk and preparation method thereof | |
| CN106214532A (en) | There is compositions of control oil bacteriostasis efficacy and preparation method thereof | |
| CN103417466A (en) | Natural moisture-preserving and skin-protecting composition and application thereof in cosmetics | |
| CN106333909B (en) | A kind of desalination red blood trace on face repairs the lotion and preparation method thereof of skin | |
| CN114053186B (en) | A kind of rose long-acting moisturizing and whitening essence water and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20141203 |