CN104056208A - Medicament for treating penis induration and preparation method thereof - Google Patents
Medicament for treating penis induration and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of medicine, and particularly relates to a medicament for treating penis induration and a preparation method thereof. The medicament is prepared from the following traditional Chinese medicine active pharmaceutical ingredients in parts by weight: 10-20 parts of herba epimedii, 10-20 parts of Curculigo orchioides, 10-20 parts of testa trionidis, 10-20 parts of fructus aurantii, 10-20 parts of manyleaf paris rhizome, 10-20 parts of deer's horn deglued, 10-20 parts of Fritillaria thunbergii, 10-20 parts of selfheal, 10-20 parts of angelica, 10-20 parts of red paeonia, 3-9 parts of radix bupleuri, 50-100 parts of roasted malt, 6-14 parts of tangerine seed, 6-14 parts of Rhizoma Zedoariae and 20-40 parts of raw oyster. The traditional Chinese medicine provided by the invention has the effects of tonifying the kidney, soothing the liver, reducing phlegm and resolving masses, and is used for treating penis induration.
Description
Technical field
The invention belongs to medical technical field, be specifically related to a kind of medicine for the treatment of induration of penis and preparation method thereof.
Background technology
Fibrous cavernositis of penis is the fibrosis lesion of albuginea of cavernous body of penis, is commonly referred to induration of penis, the highest with 40-55 years old sickness rate clinically.At present the cause of disease of induration of penis is still lacked to enough understandings, so indefinite effectively Therapeutic Method.It is relevant that current most scholar thinks that generation and penis damage repeatedly, local inflammation, endocrine regulation, vitamin E deficiency and the autoimmune of induration of penis are raised factor, this type of patient's modern medicine is taked to observe wait, oral rope E or the operative treatment of supporting one's family more, but from clinical observation on the therapeutic effect, vitamin E curative effect is general, some scholars thinks that its curative effect is equal to placebo, and that operative treatment induration of penis has is traumatic. and it is multiple to harden, postoperative very easily regeneration.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of medicine for the treatment of induration of penis and preparation method thereof.
The present invention realizes by following technical scheme:
Treat a medicine for induration of penis, by the raw material of Chinese medicine medicine of following weight portion, made:
Herba Epimedii 10-20 part, Rhizoma Curculiginis 10-20 part, Carapax Trionycis 10-20 part, Fructus Aurantii 10-20 part, Rhizoma Paridis 10-20 part, Cornu Cervi Degelatinatum 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Spica Prunellae 10-20 part, Radix Angelicae Sinensis 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Bupleuri 3-9 part, 50～100 parts of Fructus Hordei Germinatus (parched)s, Semen Citri Reticulatae 6-14 part, Rhizoma Curcumae 6-14 part, Concha Ostreae 20-40 part.
Preferably, the medicine of above-mentioned treatment induration of penis, by the raw material of Chinese medicine medicine of following weight portion, made:
Herba Epimedii 13-17 part, Rhizoma Curculiginis 13-17 part, Carapax Trionycis 13-17 part, Fructus Aurantii 13-17 part, Rhizoma Paridis 13-17 part, Cornu Cervi Degelatinatum 13-17 part, Bulbus Fritillariae Thunbergii 13-17 part, Spica Prunellae 13-17 part, Radix Angelicae Sinensis 13-17 part, Radix Paeoniae Rubra 13-17 part, Radix Bupleuri 4-8 part, Fructus Hordei Germinatus (parched) 60-90 part, Semen Citri Reticulatae 8-12 part, Rhizoma Curcumae 8-12 part, Concha Ostreae 25-35 part.
Preferred, the medicine of above-mentioned treatment induration of penis, by the raw material of Chinese medicine medicine of following weight portion, made:
15 parts of Herba Epimedii, 15 parts of Rhizoma Curculiginises, 15 parts of Carapax Trionycis, 15 parts of Fructus Aurantiis, 15 parts of Rhizoma Paridis, 15 parts of Cornu Cervi Degelatinatums, 15 parts of Bulbus Fritillariae Thunbergii, 15 parts of Spica Prunellaes, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 6 parts of Radix Bupleuri, 80 parts of Fructus Hordei Germinatus (parched)s, 10 parts of Semen Citri Reticulataes, 10 parts of Rhizoma Curcumae, 30 parts of Concha Ostreae.
The medicine of above-mentioned treatment induration of penis, the dosage form of described Chinese medicine is oral formulations.Be preferably as granule.
The preparation method of the medicine of above-mentioned treatment induration of penis, comprises the steps:
(a) Cornu Cervi Degelatinatum is ground into fine powder standby;
(b) decocting that Herba Epimedii, Rhizoma Curculiginis, Carapax Trionycis, Rhizoma Paridis, Bulbus Fritillariae Thunbergii, Spica Prunellae, Radix Paeoniae Rubra, Fructus Hordei Germinatus (parched), Semen Citri Reticulatae, Rhizoma Curcumae, Concha Ostreae 11 taste medical materials is added to 8～12 times of weight of above-mentioned medical material boils 2 times, each decoction 0.5～1.5 hour, merge the fried liquid of twice, at 60 ℃, be evaporated to half that former fried liquid amasss, incline and to cool, cold preservation 12 hours, filters, and it is 1.22～1.25 clear paste that 60 ℃ of filtrates are evaporated to relative density;
(c) by 75% soak with ethanol of 3～5 times of weight of medical material volume reflux, extract, 2 times after 10～14 hours for Fructus Aurantii, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Curcumae, each 1 hour, filter, merging filtrate, decompression recycling ethanol is to medicinal liquid without alcohol taste under 0.05～0.07MPa for filtrate, and 60 ℃ are evaporated to relative density is 1.06～1.09 clear paste;
(d) merge two parts clear paste, mix, drying under reduced pressure, pulverizes, and crosses 100 mesh sieves, is prepared into extract powder, adds Cornu Cervi Degelatinatum and pharmaceutically acceptable adjuvant, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
Described pharmaceutically acceptable adjuvant is selected from: sucrose, starch, magnesium stearate, mannitol, sorbitol, sorbic acid or potassium salt, sodium pyrosulfite, sodium sulfite, sodium thiosulfate, cysteine hydrochloride, TGA, methionine, vitamin A, vitamin C, tie up main plain E, vitamin D, azone, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, the alkali-metal carbonate of monovalence, acetate, phosphate or its aqueous solution, hydrochloric acid, acetic acid, sulphuric acid, phosphoric acid, aminoacid, sodium chloride, potassium chloride, sodium lactate, xylitol, maltose, glucose, fructose, dextran, glycine, lactose, mannitol, silicon derivative, cellulose and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, propylene glycol, ethanol, polysorbate60～80, department class～80, Cera Flava, lanoline, liquid paraffin, hexadecanol, gallate ester, fine jade, triethanolamine, basic amino acid, carbamide, allantoin, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, β～cyclodextrin, phospholipid material, Kaolin, Pulvis Talci, calcium stearate etc.
Chinese medicine of the present invention has that the kidney invigorating is soothing the liver, the effect of dissipating phlegm and resolving masses, for induration of penis.
induration of penisin the successive dynasties of traditional Chinese medical science doctor's nationality, without similar name of disease, record, but according to the syndrome performance of primary disease, can be classified " carbuncle of yin nature " sick category.From the clinical manifestation analysis of primary disease, the dirty relation of the generation of this disease and Liver and kidney two is the closest, and the heresy of cold-damp is damaged or experienced in patient's excess of sexual intercourse, penis part repeatedly, with the passing of time deficiency of kidney-QI, stagnation of QI due to depression of the liver, the stagnation of QI blood stasis, expectorant is coagulated, and hinders in penis and forms carbuncle of yin nature.Therefore, treatment should be paid attention to kidney qi to dredging the effect of sending out irritability, and the kidney invigorating of take is soothing the liver, dissipating phlegm and resolving masses is the rule for the treatment of.In drug prescription of the present invention, Radix Bupleuri, Fructus Aurantii, Fructus Hordei Germinatus (parched) dispersing the stagnated live-QI to relieve the stagnation of QI, promoting the circulation of QI to relieve pain; Bulbus Fritillariae Thunbergii, Spica Prunellae, Semen Citri Reticulatae, Concha Ostreae, Cornu Cervi Degelatinatum dissipating depression of QI eliminating stagnation, the therapeutic method to keep the adverse QI flowing downwards are reduced phlegm; Herba Epimedii, Rhizoma Curculiginis warming and recuperating the kidney-YANG, with Cornu Cervi Degelatinatum mutually 5, both can the kidney invigorating dissipating phlegm and resolving masses, the promoting the circulation of blood addiction that disappears; Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Curcumae blood circulation promoting and blood stasis dispelling, with Radix Bupleuri, Fructus Aurantii mutually 5, soothing liver-QI for relieving depression, stagnant in promoting the circulation of blood, improves microcirculation, anticoagulant, the dissolving of activation fiber albumen; Carapax Trionycis softening the hard mass is loose; Rhizoma Paridis and Spica Prunellae match, can clearing heat, releasing toxin, removing swelling piece.Take a broad view of full side, can control agent internal hormone level, promote fibrous tissue metabolism, alleviate the ischemia at penile induration position, can make again abnormal tissue collapse and dissolve.Thereby make heap soil or fertilizer over and around the roots person logical, Yu Zheda, knot person is loose, and hard person is soft.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: Herba Epimedii 150g, Rhizoma Curculiginis 150g, Carapax Trionycis 150g, Fructus Aurantii 150g, Rhizoma Paridis 150g, Cornu Cervi Degelatinatum 150g, Bulbus Fritillariae Thunbergii 150g, Spica Prunellae 150g, Radix Angelicae Sinensis 150g, Radix Paeoniae Rubra 150g, Radix Bupleuri 60g, Fructus Hordei Germinatus (parched) 800g, Semen Citri Reticulatae 100g, Rhizoma Curcumae 100g, Concha Ostreae 300g.
Preparation method:
(a) Cornu Cervi Degelatinatum is ground into fine powder standby;
(b) decocting that Herba Epimedii, Rhizoma Curculiginis, Carapax Trionycis, Rhizoma Paridis, Bulbus Fritillariae Thunbergii, Spica Prunellae, Radix Paeoniae Rubra, Fructus Hordei Germinatus (parched), Semen Citri Reticulatae, Rhizoma Curcumae, Concha Ostreae 11 taste medical materials is added to 10 times of weight of above-mentioned medical material boils 2 times, each decoction hour, merge the fried liquid of twice, at 60 ℃, be evaporated to half that former fried liquid amasss, incline and to cool, cold preservation 12 hours, filters, and it is 1.22～1.25 clear paste that 60 ℃ of filtrates are evaporated to relative density;
(c) by 75% soak with ethanol of 3～5 times of weight of medical material volume reflux, extract, 2 times after 12 hours for Fructus Aurantii, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Curcumae, each 1 hour, filter, merging filtrate, decompression recycling ethanol is to medicinal liquid without alcohol taste under 0.05～0.07MPa for filtrate, and 60 ℃ are evaporated to relative density is 1.06～1.09 clear paste;
(d) merge two parts clear paste, mix, drying under reduced pressure, pulverizes, and crosses 100 mesh sieves, is prepared into extract powder, adds Cornu Cervi Degelatinatum and pharmaceutically acceptable adjuvant, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
Prepare altogether 100 bags, every bag heavy 2g.Each 1 bag, every day three times.
Embodiment 2
Prescription: Herba Epimedii 130g, Rhizoma Curculiginis 70g, Carapax Trionycis 130g, Fructus Aurantii 170g, Rhizoma Paridis 130g, Cornu Cervi Degelatinatum 170g, Bulbus Fritillariae Thunbergii 130g, Spica Prunellae 170g, Radix Angelicae Sinensis 130g, Radix Paeoniae Rubra 170g, Radix Bupleuri 40g, Fructus Hordei Germinatus (parched) 900g, Semen Citri Reticulatae 80g, Rhizoma Curcumae 80g, Concha Ostreae 250g.
Preparation method:
(a) Cornu Cervi Degelatinatum is ground into fine powder standby;
(b) decocting that Herba Epimedii, Rhizoma Curculiginis, Carapax Trionycis, Rhizoma Paridis, Bulbus Fritillariae Thunbergii, Spica Prunellae, Radix Paeoniae Rubra, Fructus Hordei Germinatus (parched), Semen Citri Reticulatae, Rhizoma Curcumae, Concha Ostreae 11 taste medical materials is added to 8 times of weight of above-mentioned medical material boils 2 times, each decoction 0.5 hour, merge the fried liquid of twice, at 60 ℃, be evaporated to half that former fried liquid amasss, incline and to cool, cold preservation 12 hours, filters, and it is 1.22～1.25 clear paste that 60 ℃ of filtrates are evaporated to relative density;
(c) by 75% soak with ethanol of 3 times of weight of medical material volume reflux, extract, 2 times after 14 hours for Fructus Aurantii, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Curcumae, each 1 hour, filter, merging filtrate, decompression recycling ethanol is to medicinal liquid without alcohol taste under 0.05～0.07MPa for filtrate, and 60 ℃ are evaporated to relative density is 1.06～1.09 clear paste;
(d) merge two parts clear paste, mix, drying under reduced pressure, pulverizes, and crosses 100 mesh sieves, is prepared into extract powder, adds Cornu Cervi Degelatinatum and pharmaceutically acceptable adjuvant, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
Embodiment 3
Prescription: Herba Epimedii 170g, Rhizoma Curculiginis 130g, Carapax Trionycis 170g, Fructus Aurantii 130g, Rhizoma Paridis 170g, Cornu Cervi Degelatinatum 130g, Bulbus Fritillariae Thunbergii 170g, Spica Prunellae 130g, Radix Angelicae Sinensis 170g, Radix Paeoniae Rubra 130g, Radix Bupleuri 80g, Fructus Hordei Germinatus (parched) 600g, Semen Citri Reticulatae 120g, Rhizoma Curcumae 120g, Concha Ostreae 350g.
Preparation method:
(a) Cornu Cervi Degelatinatum is ground into fine powder standby;
(b) decocting that Herba Epimedii, Rhizoma Curculiginis, Carapax Trionycis, Rhizoma Paridis, Bulbus Fritillariae Thunbergii, Spica Prunellae, Radix Paeoniae Rubra, Fructus Hordei Germinatus (parched), Semen Citri Reticulatae, Rhizoma Curcumae, Concha Ostreae 11 taste medical materials is added to 12 times of weight of above-mentioned medical material boils 2 times, each decoction 1.5 hours, merge the fried liquid of twice, at 60 ℃, be evaporated to half that former fried liquid amasss, incline and to cool, cold preservation 12 hours, filters, and it is 1.22～1.25 clear paste that 60 ℃ of filtrates are evaporated to relative density;
(c) by 75% soak with ethanol of 5 times of weight of medical material volume reflux, extract, 2 times after 10 hours for Fructus Aurantii, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Curcumae, each 1 hour, filter, merging filtrate, decompression recycling ethanol is to medicinal liquid without alcohol taste under 0.05～0.07MPa for filtrate, and 60 ℃ are evaporated to relative density is 1.06～1.09 clear paste;
(d) merge two parts clear paste, mix, drying under reduced pressure, pulverizes, and crosses 100 mesh sieves, is prepared into extract powder, adds Cornu Cervi Degelatinatum and pharmaceutically acceptable adjuvant, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
Prepare altogether 100 bags, every bag heavy 2g.Each 1 bag, every day three times.
Embodiment 4
Prescription: Herba Epimedii 100g, Rhizoma Curculiginis 200g, Carapax Trionycis 100g, Fructus Aurantii 200g, Rhizoma Paridis 100g, Cornu Cervi Degelatinatum 200g, Bulbus Fritillariae Thunbergii 100g, Spica Prunellae 200g, Radix Angelicae Sinensis 100g, Radix Paeoniae Rubra 200g, Radix Bupleuri 30g, Fructus Hordei Germinatus (parched) 1000g, Semen Citri Reticulatae 60g, Rhizoma Curcumae 60g, Concha Ostreae 200g.
Preparation method is with embodiment 1.
Embodiment 5
Prescription: Herba Epimedii 200g, Rhizoma Curculiginis 100g, Carapax Trionycis 200g, Fructus Aurantii 100g, Rhizoma Paridis 200g, Cornu Cervi Degelatinatum 100g, Bulbus Fritillariae Thunbergii 200g, Spica Prunellae 1000g, Radix Angelicae Sinensis 200g, Radix Paeoniae Rubra 100g, Radix Bupleuri 90g, Fructus Hordei Germinatus (parched) 500g, Semen Citri Reticulatae 140g, Rhizoma Curcumae 140g, Concha Ostreae 400g.
Preparation method is with embodiment 1.
The preparation of embodiments of the invention l has been carried out to clinical pharmacodynamics test, and Details as Follows:
1. physical data
This organizes 36 examples, age 30-60 year, average 45 years old; The course of disease 6 months-12 years; The maximum 1.5cm of scleroma diameter; Wherein 4 examples have cystoscopy history, and 3 examples have trauma of penis history; Ultrasonic and x-ray inspection routinely, wherein 4 routine x-rays are found calcification shadow, 14LiBChao Shi local density strengthens.
2. diagnosis basis male above middle age, there is chronic progressive external limitation tuberosity in penis, asymptomatic when penis is lax, has bending and pain during erection, cavernous body of penis can touch fixing tuberosity, can be with tenderness.
3. Therapeutic Method
All patients all take the medicine for the treatment of induration of penis of the present invention after clarifying a diagnosis, and each 2 bags, every day 3 times, one after each meal.Treating 2 weeks was 1 course for the treatment of, all avoids and take pungent stimulation food, spirits and inebriant during all patient treatments.
4. criterion of therapeutical effect is cured: penile induration and crooked disappearance, and BChao Shi local density strengthens disappearance; Take a turn for the better: penile induration is dwindled, crooked improvement, BChao Shi local density is front improvement; Invalid: before and after treatment, symptom, sign are without improvement.
5. result
This is organized in 36 routine patients, cures 14 examples, 18 examples that take a turn for the better, invalid 4 examples, cure rate 38.88, total effective rate 88.88%.The shortest healing time 2 weeks, most of case healing times are 3 courses for the treatment of.
The routine patient of 6 untoward reaction 36 is showed no untoward reaction.
Claims (6)
1. treat a medicine for induration of penis, by the raw material of Chinese medicine medicine of following weight portion, made:
Herba Epimedii 10-20 part, Rhizoma Curculiginis 10-20 part, Carapax Trionycis 10-20 part, Fructus Aurantii 10-20 part, Rhizoma Paridis 10-20 part, Cornu Cervi Degelatinatum 10-20 part, Bulbus Fritillariae Thunbergii 10-20 part, Spica Prunellae 10-20 part, Radix Angelicae Sinensis 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Bupleuri 3-9 part, 50～100 parts of Fructus Hordei Germinatus (parched)s, Semen Citri Reticulatae 6-14 part, Rhizoma Curcumae 6-14 part, Concha Ostreae 20-40 part.
2. the medicine for the treatment of induration of penis according to claim 1, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, made:
Herba Epimedii 13-17 part, Rhizoma Curculiginis 13-17 part, Carapax Trionycis 13-17 part, Fructus Aurantii 13-17 part, Rhizoma Paridis 13-17 part, Cornu Cervi Degelatinatum 13-17 part, Bulbus Fritillariae Thunbergii 13-17 part, Spica Prunellae 13-17 part, Radix Angelicae Sinensis 13-17 part, Radix Paeoniae Rubra 13-17 part, Radix Bupleuri 4-8 part, Fructus Hordei Germinatus (parched) 60-90 part, Semen Citri Reticulatae 8-12 part, Rhizoma Curcumae 8-12 part, Concha Ostreae 25-35 part.
3. the medicine for the treatment of induration of penis according to claim 2, is characterized in that, by the raw material of Chinese medicine medicine of following weight portion, made:
15 parts of Herba Epimedii, 15 parts of Rhizoma Curculiginises, 15 parts of Carapax Trionycis, 15 parts of Fructus Aurantiis, 15 parts of Rhizoma Paridis, 15 parts of Cornu Cervi Degelatinatums, 15 parts of Bulbus Fritillariae Thunbergii, 15 parts of Spica Prunellaes, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Rubra, 6 parts of Radix Bupleuri, 80 parts of Fructus Hordei Germinatus (parched)s, 10 parts of Semen Citri Reticulataes, 10 parts of Rhizoma Curcumae, 30 parts of Concha Ostreae.
4. according to the medicine of the treatment induration of penis described in claim 1 or 2 or 3, it is characterized in that, the dosage form of described Chinese medicine is oral formulations.
5. according to the medicine of the treatment induration of penis described in claim 1 or 2 or 3, it is characterized in that, the dosage form of described Chinese medicine is granule.
6. the preparation method of the medicine of the treatment induration of penis described in claim 1 or 2 or 3, comprises the steps:
(a) Cornu Cervi Degelatinatum is ground into fine powder standby;
(b) decocting that Herba Epimedii, Rhizoma Curculiginis, Carapax Trionycis, Rhizoma Paridis, Bulbus Fritillariae Thunbergii, Spica Prunellae, Radix Paeoniae Rubra, Fructus Hordei Germinatus (parched), Semen Citri Reticulatae, Rhizoma Curcumae, Concha Ostreae 11 taste medical materials is added to 8～12 times of weight of above-mentioned medical material boils 2 times, each decoction 0.5～1.5 hour, merge the fried liquid of twice, at 60 ℃, be evaporated to half that former fried liquid amasss, incline and to cool, cold preservation 12 hours, filters, and it is 1.22～1.25 clear paste that 60 ℃ of filtrates are evaporated to relative density;
(c) by 75% soak with ethanol of 3～5 times of weight of medical material volume reflux, extract, 2 times after 10～14 hours for Fructus Aurantii, Radix Angelicae Sinensis, Radix Bupleuri, Rhizoma Curcumae, each 1 hour, filter, merging filtrate, decompression recycling ethanol is to medicinal liquid without alcohol taste under 0.05～0.07MPa for filtrate, and 60 ℃ are evaporated to relative density is 1.06～1.09 clear paste;
(d) merge two parts clear paste, mix, drying under reduced pressure, pulverizes, and crosses 100 mesh sieves, is prepared into extract powder, adds Cornu Cervi Degelatinatum and pharmaceutically acceptable adjuvant, mixes, and makes wetting agent granulate with 75% ethanol, dry, granulate, and granulation agent, obtains.
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| CN104288695A (en) * | 2014-10-23 | 2015-01-21 | 滨州医学院 | Medicament for treating peyronie's disease and preparation method of medicament |
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| CN106390017A (en) * | 2016-09-30 | 2017-02-15 | 毛华养 | Multi-TCM (Traditional Chinese Medicine) composition for effectively treating macrodactyly |
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| KR101257578B1 (en) * | 2010-12-24 | 2013-04-23 | 대전대학교 산학협력단 | Herbal Medicnes for Treating Diabetic Neuropathy |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104288695A (en) * | 2014-10-23 | 2015-01-21 | 滨州医学院 | Medicament for treating peyronie's disease and preparation method of medicament |
| CN104998214A (en) * | 2015-08-17 | 2015-10-28 | 盖文涛 | Traditional Chinese medicine for treating peyronie disease |
| CN106390017A (en) * | 2016-09-30 | 2017-02-15 | 毛华养 | Multi-TCM (Traditional Chinese Medicine) composition for effectively treating macrodactyly |
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Application publication date: 20140924 |
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