CN103908588A - Traditional Chinese medicine preparation used for treating hypertension, and preparation method thereof - Google Patents
Traditional Chinese medicine preparation used for treating hypertension, and preparation method thereof Download PDFInfo
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- CN103908588A CN103908588A CN201410090830.8A CN201410090830A CN103908588A CN 103908588 A CN103908588 A CN 103908588A CN 201410090830 A CN201410090830 A CN 201410090830A CN 103908588 A CN103908588 A CN 103908588A
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- 239000003814 drug Substances 0.000 title claims abstract description 43
- 206010020772 Hypertension Diseases 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 13
- 229940079593 drug Drugs 0.000 claims description 27
- 239000003390 Chinese drug Substances 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 230000001631 hypertensive effect Effects 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 15
- 238000002156 mixing Methods 0.000 claims description 15
- 241000255791 Bombyx Species 0.000 claims description 12
- 238000001914 filtration Methods 0.000 claims description 10
- 241000209128 Bambusa Species 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 5
- 238000002791 soaking Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 6
- 230000000857 drug effect Effects 0.000 abstract description 4
- 241000244939 Menispermum dauricum Species 0.000 abstract 1
- 241000382353 Pupa Species 0.000 abstract 1
- 240000003801 Sigesbeckia orientalis Species 0.000 abstract 1
- 235000003407 Sigesbeckia orientalis Nutrition 0.000 abstract 1
- 241000489523 Veratrum Species 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 244000247968 finger leaf morning glory Species 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
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Abstract
The invention discloses a traditional Chinese medicine preparation used for treating hypertension, and a preparation method thereof. The traditional Chinese medicine preparation is composed of following raw material ingredients, by mass, 9 to 13 parts of siegesbeckia orientalis, 8 to 12 parts of menispermum dauricum, 12 to 15 parts of pupa bombycis batryticatus, 6 to 12 parts of black false hellebore, 13 to 17 parts of root of fingerleaf morningglory, 14 to 18 parts of venenum bufonis, 8 to 12 parts of calculus bovis, and 7 to 11 parts of concretio silicea bambusae. Compared with existing technology, the traditional Chinese medicine preparation possesses following advantages: on the one hand, drug effect is obvious, no toxic or side effect is caused, drug dependence of patients is not caused, and relapse is not easily caused; and on the other hand, the preparation method is simple and convenient, and the traditional Chinese medicine preparation is suitable for clinical application.
Description
Technical field
The present invention relates to Chinese medicine preparation and preparation method thereof, relate in particular to one and treat hypertensive Chinese drugs agentia and preparation method thereof.
Background technology
Hypertension is modal cardiovascular diseases, is the great public health problem in global range.The Chinese residents nutrition of 2004 and the demonstration of Health Situation survey result, China 18 years old and above prevalence of hypertension rate are 18.8%, estimate that national number of patients exceedes 1.6 hundred million.Compared with 1991, prevalence rises 31%, and number of patients increases by approximately more than 7 000 ten thousand people.At present hypertension is that a kind of to patient's puzzlement and very harmful disease, especially old people, its potential risk is very big, there is no at present the particularly preferred Western medicine of effect or Chinese medicine and treats for it, and the treatment recurrent of existing medicine is conventionally very high.
Summary of the invention
Goal of the invention: in order to solve the existing problem of prior art, the invention provides a kind of drug effect significantly, be difficult for hypertensive Chinese drugs agentia for the treatment of of recurrence and preparation method thereof.
Technical scheme: for achieving the above object; the present invention is by the following technical solutions: one is treated hypertensive Chinese drugs agentia; form 9～13 parts of: Herba Siegesbeckiae, 8～12 parts of Caulis menispermis by following crude drug according to quality meter; 12～15 parts of Bombyx Batryticatus; 6～12 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 13～17 parts of Radix ipomoeae digitatae, 14～18 parts of Venenum Bufoniss; 8～12 parts of true Calculus Boviss, 7～11 parts of Concretio Silicea Bambusaes.
As a further improvement on the present invention, described each crude drug consumption is according to 12 parts of quality meter: Herba Siegesbeckiae composed as follows, 10 parts of Caulis menispermis, 13 parts of Bombyx Batryticatus, 7 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 16 parts of Radix ipomoeae digitatae, 15 parts of Venenum Bufoniss, 10 parts of true Calculus Boviss, 9 parts of Concretio Silicea Bambusaes.
The preparation method of the hypertensive Chinese drugs agentia of above-mentioned treatment, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) Shou Xian soaks Herba Siegesbeckiae, Rhizoma et radix veratri (Radix Rhizoma Veratri), three kinds of crude drug mixing and water addings of Radix ipomoeae digitatae, water consumption is 12～14 times of three kinds of crude drug weight summations, after soaking 40min, rear slow fire continuation decoction 40～60min is boiled in big fire, add again Concretio Silicea Bambusae, true Calculus Bovis, big fire is boiled after rear slow fire continues to decoct 20～30min and is leached medicinal liquid, obtains filtering residue;
(3) first to Caulis menispermi, Bombyx Batryticatus and Venenum Bufonis mixing and water adding is soaked to 40min, water consumption is 5～7 times of three kinds of crude drug weight summations, big fire is boiled rear slow fire and is continued to decoct 15～25min, add again the filtering residue of step (2) gained to soak big fire after 25min and boil, continue to leach medicinal liquid after slow fire boiling 25～40min;
(4) medicinal liquid step (2), (3) being obtained obtains the hypertensive Chinese drugs agentia of described treatment after mixing.
For better guaranteeing decocting for Chinese herbal medicine effect, described decoction container is marmite or enamel ware.
Beneficial effect: one provided by the present invention is treated hypertensive Chinese drugs agentia and preparation method thereof, compared with prior art has the following advantages: drug effect is remarkable on the one hand, has no side effect, and can not cause the dependency of patient to medicine, is difficult for recurrence; On the other hand and preparation method easy, be suitable for clinical practice.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further described:
Embodiment 1:
One is treated hypertensive Chinese drugs agentia, forms 9 parts of: Herba Siegesbeckiae, 8 parts of Caulis menispermis, 12 parts of Bombyx Batryticatus, 6 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 13 parts of Radix ipomoeae digitatae, 14 parts of Venenum Bufoniss, 8 parts of true Calculus Boviss, 7 parts of Concretio Silicea Bambusaes by following crude drug according to quality meter.
The preparation method of the hypertensive Chinese drugs agentia of above-mentioned treatment, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) adopt marmite to carry out the decoction of medicament, Shou Xian soaks Herba Siegesbeckiae, Rhizoma et radix veratri (Radix Rhizoma Veratri), three kinds of crude drug mixing and water addings of Radix ipomoeae digitatae, water consumption is 12 times of three kinds of crude drug weight summations, after soaking 40min, rear slow fire continuation decoction 40min is boiled in big fire, add again Concretio Silicea Bambusae, true Calculus Bovis, big fire is boiled after rear slow fire continues to decoct 20min and is leached medicinal liquid, obtains filtering residue;
(3) first to Caulis menispermi, Bombyx Batryticatus and Venenum Bufonis mixing and water adding is soaked to 40min, water consumption is 5 times of three kinds of crude drug weight summations, big fire is boiled rear slow fire and is continued to decoct 15min, then after adding the filtering residue of step (2) gained to soak 25min, big fire is boiled, and continues to leach medicinal liquid after slow fire boiling 25min;
(4) medicinal liquid step (2), (3) being obtained obtains the hypertensive Chinese drugs agentia of described treatment after mixing.
Embodiment 2:
One is treated hypertensive Chinese drugs agentia, forms 12 parts of: Herba Siegesbeckiae, 10 parts of Caulis menispermis, 13 parts of Bombyx Batryticatus, 7 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 16 parts of Radix ipomoeae digitatae, 15 parts of Venenum Bufoniss, 10 parts of true Calculus Boviss, 9 parts of Concretio Silicea Bambusaes by following crude drug according to quality meter.
The preparation method of the hypertensive Chinese drugs agentia of above-mentioned treatment, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) adopt marmite to carry out the decoction of medicament, Shou Xian soaks Herba Siegesbeckiae, Rhizoma et radix veratri (Radix Rhizoma Veratri), three kinds of crude drug mixing and water addings of Radix ipomoeae digitatae, water consumption is 13 times of three kinds of crude drug weight summations, after soaking 40min, rear slow fire continuation decoction 50min is boiled in big fire, add again Concretio Silicea Bambusae, true Calculus Bovis, big fire is boiled after rear slow fire continues to decoct 25min and is leached medicinal liquid, obtains filtering residue;
(3) first to Caulis menispermi, Bombyx Batryticatus and Venenum Bufonis mixing and water adding is soaked to 40min, water consumption is 6 times of three kinds of crude drug weight summations, big fire is boiled rear slow fire and is continued to decoct 20min, then after adding the filtering residue of step (2) gained to soak 25min, big fire is boiled, and continues to leach medicinal liquid after slow fire boiling 35min;
(4) medicinal liquid step (2), (3) being obtained obtains the hypertensive Chinese drugs agentia of described treatment after mixing.
Embodiment 3:
One is treated hypertensive Chinese drugs agentia, forms 13 parts of: Herba Siegesbeckiae, 12 parts of Caulis menispermis, 15 parts of Bombyx Batryticatus, 12 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 17 parts of Radix ipomoeae digitatae, 18 parts of Venenum Bufoniss, 12 parts of true Calculus Boviss, 11 parts of Concretio Silicea Bambusaes by following crude drug according to quality meter.
The preparation method of the hypertensive Chinese drugs agentia of above-mentioned treatment, comprises the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) adopt marmite to carry out the decoction of medicament, Shou Xian soaks Herba Siegesbeckiae, Rhizoma et radix veratri (Radix Rhizoma Veratri), three kinds of crude drug mixing and water addings of Radix ipomoeae digitatae, water consumption is 14 times of three kinds of crude drug weight summations, after soaking 40min, rear slow fire continuation decoction 60min is boiled in big fire, add again Concretio Silicea Bambusae, true Calculus Bovis, big fire is boiled after rear slow fire continues to decoct 30min and is leached medicinal liquid, obtains filtering residue;
(3) first to Caulis menispermi, Bombyx Batryticatus and Venenum Bufonis mixing and water adding is soaked to 40min, water consumption is 7 times of three kinds of crude drug weight summations, big fire is boiled rear slow fire and is continued to decoct 25min, then after adding the filtering residue of step (2) gained to soak 25min, big fire is boiled, and continues to leach medicinal liquid after slow fire boiling 40min;
(4) medicinal liquid step (2), (3) being obtained obtains the hypertensive Chinese drugs agentia of described treatment after mixing.
Further set forth below the beneficial effect of medicine of the present invention by clinical case:
(1) clinical data and Therapeutic Method
With test group treatment hyperpietic 50 examples, compare with matched group 50 examples.
test group:in the present invention, the Chinese drugs agentia described in embodiment 1-3, is decocted in water for oral dose, every day potion, sooner or later sub-service.Taking medicine continuously 15 days is 1 course for the treatment of;
matched group:adopting conventional medicine to treat, every day three times, 15 days was 1 course for the treatment of.
Test group and matched group patient are fully recovered in 3 months and paid a return visit, investigate and record hypertension recurrence.
(2) curative effect determinate standard
A) effective: blood pressure reaches standard blood pressure, stablize, do not go up in a short time;
B) effective: blood pressure obviously reduces, and tends towards stability;
C) invalid: blood pressure is without obvious reduction trend.
(3) clinical effectiveness
Test group and the comparison of matched group curative effect, in table 1.
Table 1 test group and the comparison of matched group curative effect
| ? | Effective | Effectively | Invalid | Add up to | Effective percentage (%) | Relapse rate (%) |
| Test group | 28 | 17 | 5 | 50 | 90 | 10 |
| Matched group | 15 | 13 | 22 | 50 | 56 | 60 |
Clinical effectiveness shows: test group treatment hyperpietic 50 examples, total effective rate reaches in 90%, three month 10% relapse rate, with the total effective rate of matched group 50 examples 56% and in three months 60% relapse rate compare, be obviously better than matched group.Illustrate that hypertension therapy of the present invention is evident in efficacy, drug effect is remarkable and be difficult for recurrence, has good promotional value.
Should be understood that, the above specific embodiment is only not used in and limits the scope of the invention for the present invention is described, after having read the present invention, those skilled in the art all fall within the application's claims limited range to the modification of the various equivalent form of values of the present invention.
Claims (3)
1. the hypertensive Chinese drugs agentia for the treatment of, is characterized in that, comprises the crude drug of following parts by weight: 9～13 parts of Herba Siegesbeckiae, 8～12 parts of Caulis menispermis; 12～15 parts of Bombyx Batryticatus, 6～12 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 13～17 parts of Radix ipomoeae digitatae; 14～18 parts of Venenum Bufoniss, 8～12 parts of true Calculus Boviss, 7～11 parts of Concretio Silicea Bambusaes.
2. the hypertensive Chinese drugs agentia for the treatment of according to claim 1, is characterized in that, comprises 12 parts of crude drug: Herba Siegesbeckiae, 10 parts of the Caulis menispermis of following parts by weight, 13 parts of Bombyx Batryticatus, 7 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 16 parts of Radix ipomoeae digitatae, 15 parts of Venenum Bufoniss, 10 parts of true Calculus Boviss, 9 parts of Concretio Silicea Bambusaes.
3. a preparation method for the hypertensive Chinese drugs agentia for the treatment of as claimed in claim 1, is characterized in that comprising the following steps:
(1) all crude drug are ready to according to institute's expense;
(2) Shou Xian soaks Herba Siegesbeckiae, Rhizoma et radix veratri (Radix Rhizoma Veratri), three kinds of crude drug mixing and water addings of Radix ipomoeae digitatae, water consumption is 12～14 times of three kinds of crude drug weight summations, after soaking 40min, rear slow fire continuation decoction 40～60min is boiled in big fire, add again Concretio Silicea Bambusae, true Calculus Bovis, big fire is boiled after rear slow fire continues to decoct 20～30min and is leached medicinal liquid, obtains filtering residue;
(3) first to Caulis menispermi, Bombyx Batryticatus and Venenum Bufonis mixing and water adding is soaked to 40min, water consumption is 5～7 times of three kinds of crude drug weight summations, big fire is boiled rear slow fire and is continued to decoct 15～25min, add again the filtering residue of step (2) gained to soak big fire after 25min and boil, continue to leach medicinal liquid after slow fire boiling 25～40min;
(4) medicinal liquid step (2), (3) being obtained obtains the hypertensive Chinese drugs agentia of described treatment after mixing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410090830.8A CN103908588A (en) | 2014-03-13 | 2014-03-13 | Traditional Chinese medicine preparation used for treating hypertension, and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410090830.8A CN103908588A (en) | 2014-03-13 | 2014-03-13 | Traditional Chinese medicine preparation used for treating hypertension, and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058832A (en) * | 2009-11-12 | 2011-05-18 | 刘丽颖 | Medicine composition preparation and preparation method thereof |
| CN102846786A (en) * | 2012-09-25 | 2013-01-02 | 南京泽朗农业发展有限公司 | Medicinal preparation for treating hypertension and preparation method thereof |
| KR20130030620A (en) * | 2011-09-19 | 2013-03-27 | 세명대학교 산학협력단 | Composition for preventing and treating of pulmonary emphysema and pulmonary hypertension, comprising an extract of alismatis rhizoma as an effective component |
| CN103611075A (en) * | 2013-09-13 | 2014-03-05 | 辽宁仙草堂药业股份有限公司 | Bezoar refreshing preparation and preparation method thereof |
-
2014
- 2014-03-13 CN CN201410090830.8A patent/CN103908588A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058832A (en) * | 2009-11-12 | 2011-05-18 | 刘丽颖 | Medicine composition preparation and preparation method thereof |
| KR20130030620A (en) * | 2011-09-19 | 2013-03-27 | 세명대학교 산학협력단 | Composition for preventing and treating of pulmonary emphysema and pulmonary hypertension, comprising an extract of alismatis rhizoma as an effective component |
| CN102846786A (en) * | 2012-09-25 | 2013-01-02 | 南京泽朗农业发展有限公司 | Medicinal preparation for treating hypertension and preparation method thereof |
| CN103611075A (en) * | 2013-09-13 | 2014-03-05 | 辽宁仙草堂药业股份有限公司 | Bezoar refreshing preparation and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 王琛等: "中医药治疗高血压病的研究进展", 《中华中医药学刊》 * |
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Application publication date: 20140709 |