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CN103784927A - Traditional Chinese medicinal drinking water preparation for resisting stress reaction of livestock and poultry during transportation - Google Patents

Traditional Chinese medicinal drinking water preparation for resisting stress reaction of livestock and poultry during transportation Download PDF

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Publication number
CN103784927A
CN103784927A CN201410061394.1A CN201410061394A CN103784927A CN 103784927 A CN103784927 A CN 103784927A CN 201410061394 A CN201410061394 A CN 201410061394A CN 103784927 A CN103784927 A CN 103784927A
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livestock
poultry
drinking water
chinese medicine
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CN103784927B (en
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李立顺
时维静
王甫成
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Anhui Heng Yuan Pharmaceutcal Corp Ltd
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Anhui University of Science and Technology
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Abstract

本发明公开了一种抗畜禽运输应激反应的中药饮水剂,由下列重量份的原料制成:金沸草1-5份、制半夏2-8份、陈皮2-5份、广藿香2-5份、茯苓2-6份、粉葛根3-10份、生姜1-3份、合欢皮3-6份、黄芩1-5份;辅料:表面活性剂0.05-0.2份、防腐剂0.02-0.2份。本发明采用上述中药配伍,制备成中药饮水剂,于畜禽运输前后使用,调节脏腑功能,调畅气血,增强免疫力,提高畜禽对运输的耐受力,长途运输中间加入饮水中,还可镇静安神,调顺胃肠之气,芳香疏散,以防止风、寒、暑、湿等外邪侵袭。本发明无药物残留、安全无毒副作用,制备成饮水剂形式,方便使用,对畜禽无惊吓,而且气味芳香,畜禽喜饮。The invention discloses a traditional Chinese medicine drinking water preparation for resisting the stress reaction of livestock and poultry transportation, which is prepared from the following raw materials in parts by weight: 1-5 parts of Jinbocao, 2-8 parts of pinellia chinensis, 2-5 parts of tangerine peel, Huoxiang 2-5 parts, Poria cocos 2-6 parts, kudzu root 3-10 parts, ginger 1-3 parts, acacia bark 3-6 parts, scutellaria baicalensis 1-5 parts; accessories: surfactant 0.05-0.2 parts, antiseptic Dose 0.02-0.2 part. The present invention adopts the compatibility of the above-mentioned traditional Chinese medicines to prepare Chinese medicine drinking water, which is used before and after the transport of livestock and poultry to regulate visceral functions, regulate qi and blood, enhance immunity, improve the tolerance of livestock and poultry to transport, and add drinking water in the middle of long-distance transport. It can also calm the nerves, adjust the qi of the stomach and intestines, and evacuate the fragrance to prevent the invasion of wind, cold, heat, damp and other exogenous evils. The invention has no drug residue, is safe and has no side effects, is prepared in the form of a drinking water preparation, is convenient to use, has no frightening effect on livestock and poultry, and has a fragrant smell, which the livestock and poultry like to drink.

Description

A kind of Chinese medicine drinking agent of anti-poultry transport stress reaction
 
Technical field
The present invention relates to a kind of veterinary drug, relate in particular to a kind of Chinese medicine drinking agent of anti-poultry transport stress reaction, belong to animal medicine field.
 
Background technology
Along with the prosperity of domestic and international poultry trade, transportation poultry are increasing, decline, animal meat quality declines, laying eggs lags behind or stop because transport stress causes poultry morbidities, fertility performance, even dead or disable, and cause huge economic loss to aquaculture.Stress come from front the chasing, driveing and Baoding poultry of transportation, crowded between poultry, fight in transit, hunger and thirst, noise, car and boat jolt, the interior miniclimate air pollution of car and boat etc., make body in a kind of " anxiety " state, bring out that poultry nerve is highly excited, hormonal system imbalance, gastrointestinal dysfunction, fervescence, immunologic function degression etc.
Control poultry transport stress reaction at present, the main chemicals that uses calm stable effect, as chlorpromazine, reserpine, bromo agent etc., added before 2~3 days in feedstuff for prevention in transportation, or face before transportation with dantrolene sodium, xylazine, pentobarbital sodium intravenous etc.These chemicalses more or less have infringement to liver, kidney, toxic side effect.In addition, intravenous injection also easily causes the stress of scaring, pain to domestic animal.
 
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine drinking agent of anti-poultry transport stress reaction of making by the Chinese medicine ingredients of safe without toxic side effect, drug residue free is provided, can regulate poultry function, adjust smooth QI and blood, enhancing immunity, improve the tolerance of poultry to transportation, make drinking agent form, be convenient to poultry and drink.
The present invention adopts following technical scheme to achieve these goals:
A Chinese medicine drinking agent for anti-poultry transport stress reaction, is made up of the raw material of following weight portion: Herba Inulae 1-5 part, Rhizoma Pinelliae Preparata 2-8 part, Pericarpium Citri Reticulatae 2-5 part, Herba Pogostemonis 2-5 part, Poria 2-6 part, RADIX PUERARIAE 3-10 part, Rhizoma Zingiberis Recens 1-3 part, Cortex Albiziae 3-6 part, Radix Scutellariae 1-5 part;
Adjuvant used: surfactant 0.05-0.2 part, antiseptic 0.02-0.2 part.
Preferably, the Chinese medicine drinking agent of described anti-poultry transport stress reaction, is made up of the raw material of following weight portion: 2 parts of Herba Inulae, 3 parts of Rhizoma Pinelliae Preparata, 3 parts of Pericarpium Citri Reticulataes, 2 parts of Herba Pogostemonis, 3 parts, Poria, 4 parts of RADIX PUERARIAE, 1 part, Rhizoma Zingiberis Recens, 3 parts of Cortex Albiziaes, 2 parts of Radix Scutellariaes;
Adjuvant used: 0.08 part, surfactant, 0.05 part of antiseptic.
Described surfactant is the one in Tween20, Tween40, Tween80.
Described antiseptic is one or more in sodium benzoate, ethyl hydroxybenzoate, methyl hydroxybenzoate, potassium sorbate.
The preparation method of the Chinese medicine drinking agent of described anti-poultry transport stress reaction, comprises following preparation process:
(1) adopt respectively steam distillation to extract volatile oil Pericarpium Citri Reticulatae, Herba Pogostemonis by above-mentioned weight ratio, the airtight preservation of volatile oil of extracting, remaining decocting part is taken out medicinal residues and is obtained water, medicinal residues add decocting once again, remove slag, then the water obtaining with steam distillation merges, and obtains aqueous extract;
(2) Herba Inulae, Rhizoma Pinelliae Preparata, Poria, RADIX PUERARIAE, Rhizoma Zingiberis Recens, Cortex Albiziae, Radix Scutellariae are mixed, decoct with water 2-3 time, after removing slag with step (1) in Pericarpium Citri Reticulatae, Herba Pogostemonis aqueous extract be mixed to get medicinal liquid, then medicinal liquid is concentrated into the 2-8 of medical material gross weight doubly, obtain concentrated solution;
(3) volatile oil extracting in step (1) is mixed with surfactant, after mixing, join in the concentrated solution of step (2), stir, finally add antiseptic, subpackage, sealing.
Usage: the previous day or the same day in poultry transportation add in drinking-water, have drunk in 2-4 hour, and long-distance transport can on the way be drunk water to add and be drunk, and drinks continuously 2 days to destination again, and it is normal that poultry recover substantially.
Consumption: 50kg-200kg poultry/100mL.
Chinese medicine is thought " excessive fright leading to disturbance of QI ", " dizziness must be caused by phlegm ", " calm do not do dizzy ", " dizziness must be due to deficiency ".Poultry transport stress reaction, how because of mechanism of qi disorder, raw expectorant, raw wind, light a fire due to, show as the abnormal and gastrointestinal reaction of spirit more.For this paathogenic factor, calm the nerves when regulating the flow of vital energy, invigorating the spleen and regulating the stomach.
Herba Inulae claims again HERBA INULAE, is the stem and leaf of catananche's Flos Inulae or Inula britannica, and the function of its regulating functional activities of qi is better than flower, and for this disease, mechanism of qi is normal again, and disturbance of QI can be determined, dizzy stopping.It is wet and reduce phlegm turbidly that Rhizoma Pinelliae Preparata is usually used in dry spleen, falls gastric qi and preventing or arresting vomiting is told.Pericarpium Citri Reticulatae is the good merchantable brand of regulating qi-flowing for strengthening spleen, action temperature and, again can dampness.Herba Pogostemonis fragrance is amusing, removing dampness preventing or arresting vomiting.Poria replenishing QI to invigorate the spleen, mind tranquilizing and the heart calming.RADIX PUERARIAE can inspire the gas of the clear sun of taste to rise, and can give birth to again Jian and quench the thirst, yang invigorating antidiarrheal.Cortex Albiziae settling five organs, and will, resolving stagnation for tranquilization, is happy heart and tranquilizing mind key medicine.The kind damp-heat in upper-JIAO pathogenic fire of letting out clearly of Radix Scutellariae, solution breast gastral cavity painful abdominal mass is vexed.Rhizoma Zingiberis Recens stomach warming preventing or arresting vomiting, and middle sending down the abnormal ascending QI, and can restrict the toxicity of the Rhizoma Pinelliae.
Compared with the prior art, beneficial effect of the present invention is as follows:
The present invention adopts above-mentioned drug matching, is prepared into Chinese medicine drinking agent, can make frightened disorderly termination, and ataraxy, mechanism of qi is adjusted suitable, the strong fortune of taste.Before and after poultry transportation, use, by regulating function, adjust smooth QI and blood, enhancing immunity, improve the tolerance of poultry to transportation, in the middle of long-distance transport, adds in drinking-water, also can tranquillizing and allaying excitement, adjust along the gas of gastrointestinal, fragrance is evacuated, to prevent wind, cold, summer-heat, the exopathogen invasion and attack such as wet.The present invention adopts Chinese medicine ingredients, and drug residue free, safe without toxic side effect are prepared into drinking agent form, easy to use, to poultry without scaring, and fragrant odour of the present invention, poultry happiness drink.
 
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1:
A Chinese medicine drinking agent for anti-poultry transport stress reaction, is made up of the raw material of following weight portion: 2 parts of Herba Inulae, 3 parts of Rhizoma Pinelliae Preparata, 3 parts of Pericarpium Citri Reticulataes, 2 parts of Herba Pogostemonis, 3 parts, Poria, 4 parts of RADIX PUERARIAE, 1 part, Rhizoma Zingiberis Recens, 3 parts of Cortex Albiziaes, 2 parts of Radix Scutellariaes; 0.08 part of adjuvant used: Tween20,0.05 part of sodium benzoate.
Preparation method:
(1) adopt respectively steam distillation to extract volatile oil Pericarpium Citri Reticulatae, Herba Pogostemonis by above-mentioned weight ratio, the airtight preservation of volatile oil of extracting, remaining decocting part is taken out medicinal residues and is obtained water, medicinal residues add decocting once again, remove slag, then the water obtaining with steam distillation merges, and obtains aqueous extract;
(2) Herba Inulae, Rhizoma Pinelliae Preparata, Poria, RADIX PUERARIAE, Rhizoma Zingiberis Recens, Cortex Albiziae, Radix Scutellariae are mixed, decoct with water 3 times, after removing slag with step (1) in Pericarpium Citri Reticulatae, Herba Pogostemonis aqueous extract be mixed to get medicinal liquid, then medicinal liquid is concentrated into 5 times of medical material gross weight, obtain concentrated solution;
(3) volatile oil extracting in step (1) is mixed with Tween20, after mixing, join in the concentrated solution of step (2), stir, finally add sodium benzoate, subpackage, sealing.
Usage and dosage: added in drinking-water the same day of poultry transportation by 100kg poultry/100mL, and drunk in 3 hours, and drank continuously again 2 days to destination.
Embodiment 2:
A Chinese medicine drinking agent for anti-poultry transport stress reaction, is made up of the raw material of following weight portion: 3 parts of Herba Inulae, 4 parts of Rhizoma Pinelliae Preparata, 3 parts of Pericarpium Citri Reticulataes, 3 parts of Herba Pogostemonis, 4 parts, Poria, 5 parts of RADIX PUERARIAE, 2 parts, Rhizoma Zingiberis Recens, 4 parts of Cortex Albiziaes, 3 parts of Radix Scutellariaes; 1.2 parts of adjuvant used: Tween40,0.08 part of ethyl hydroxybenzoate, 0.03 part of methyl hydroxybenzoate.
Preparation method:
(1) adopt respectively steam distillation to extract volatile oil Pericarpium Citri Reticulatae, Herba Pogostemonis by above-mentioned weight ratio, the airtight preservation of volatile oil of extracting, remaining decocting part is taken out medicinal residues and is obtained water, medicinal residues add decocting once again, remove slag, then the water obtaining with steam distillation merges, and obtains aqueous extract;
(2) Herba Inulae, Rhizoma Pinelliae Preparata, Poria, RADIX PUERARIAE, Rhizoma Zingiberis Recens, Cortex Albiziae, Radix Scutellariae are mixed, decoct with water 3 times, after removing slag with step (1) in Pericarpium Citri Reticulatae, Herba Pogostemonis aqueous extract be mixed to get medicinal liquid, then medicinal liquid is concentrated into 8 times of medical material gross weight, obtain concentrated solution;
(3) volatile oil extracting in step (1) is mixed with Tween40, after mixing, join in the concentrated solution of step (2), stir, finally add ethyl hydroxybenzoate, methyl hydroxybenzoate, subpackage, sealing.
Usage and dosage: add in drinking-water the previous day of poultry transportation by 80kg poultry/100mL, drunk in 2 hours, long-distance transport can on the way be drunk water to add and be drunk, and drinks continuously 2 days to destination again.
Embodiment 3:
A Chinese medicine drinking agent for anti-poultry transport stress reaction, is made up of the raw material of following weight portion: 5 parts of Herba Inulae, 8 parts of Rhizoma Pinelliae Preparata, 5 parts of Pericarpium Citri Reticulataes, 5 parts of Herba Pogostemonis, 6 parts, Poria, 10 parts of RADIX PUERARIAE, 3 parts, Rhizoma Zingiberis Recens, 6 parts of Cortex Albiziaes, 5 parts of Radix Scutellariaes; 0.2 part of adjuvant used: Tween80,0.8 part of methyl hydroxybenzoate, 1.2 parts of potassium sorbate.
Preparation method:
(1) adopt respectively steam distillation to extract volatile oil Pericarpium Citri Reticulatae, Herba Pogostemonis by above-mentioned weight ratio, the airtight preservation of volatile oil of extracting, remaining decocting part is taken out medicinal residues and is obtained water, medicinal residues add decocting once again, remove slag, then the water obtaining with steam distillation merges, and obtains aqueous extract;
(2) Herba Inulae, Rhizoma Pinelliae Preparata, Poria, RADIX PUERARIAE, Rhizoma Zingiberis Recens, Cortex Albiziae, Radix Scutellariae are mixed, decoct with water 3 times, after removing slag with step (1) in Pericarpium Citri Reticulatae, Herba Pogostemonis aqueous extract be mixed to get medicinal liquid, then medicinal liquid is concentrated into 4 times of medical material gross weight, obtain concentrated solution;
(3) volatile oil extracting in step (1) is mixed with surfactant, after mixing, join in the concentrated solution of step (2), stir, finally add antiseptic, subpackage, sealing.
Usage and dosage: add in drinking-water the previous day of poultry transportation by 200kg poultry/100mL, drunk in 3 hours, long-distance transport can on the way be drunk water to add and be drunk, and drinks continuously 2 days to destination again.
Test example:
(1), from 200 chickens of Luoyang buying, to Hefei, be divided at random two groups through Automobile Transportation, matched group and of the present invention group, 100 every group, male and female half and half.Matched group is all identical with drinking-water with of the present invention group of feedstuff, matched group does not give any medicine and bio-occlusion drinking water just, and of the present invention group is set out in Luoyang and add the previous day in drinking water, and consumption is by every 100kg/100ml, in transportation, also drink once, arrive Hefei and continue again to drink 2 days.The chicken number that records transport stress symptoms such as occurring lethargy, crop swelling, anorexia, have loose bowels, lose weight in process of the test, calculates its incidence rate; And record is because transport stress causes ill chicken number, calculates prevalence.Result is as following table 1:
Table 1:
Figure 2014100613941100002DEST_PATH_IMAGE002
As shown in Table 1, in the present invention, chicken transport stress symptom incidence rate and the prevalence that causes because of transport stress are all starkly lower than matched group, show that the present invention can resist the reaction of chicken transport stress.
(2), from 100 pigs of Weifang, Shandong buying, to Hefei, be divided at random two groups through Automobile Transportation, matched group and of the present invention group, 50 every group, male and female half and half.Matched group is all identical with drinking-water with of the present invention group of feedstuff, matched group does not give any medicine and bio-occlusion drinking water just, and of the present invention group is set out in Weifang and added the same day in drinking water, and consumption is by every 200kg/100ml, in transportation, also drink once, arrive Hefei and continue again to drink 2 days.In process of the test, record occurs that spirit is depressed or uneasy, accelerated breathing, and inappetence, fervescence, the whole-body muscle pig number of transport stress symptom such as tremble, calculates its incidence rate; And record is because transport stress causes ill pig number, calculates prevalence.Result is as following table 2:
Table 2:
Figure 2014100613941100002DEST_PATH_IMAGE004
As shown in Table 2, in the present invention, pig transport stress symptom incidence rate and the prevalence that causes because of transport stress are all starkly lower than matched group, show that the present invention can resist the reaction of pig transport stress.
In addition, also, through multiple fowl poultry kind test and test of many times, all obtain satisfied result.

Claims (5)

1.一种抗畜禽运输应激反应的中药饮水剂,其特征在于:由下列重量份的原料制成:金沸草1-5份、制半夏2-8份、陈皮2-5份、广藿香2-5份、茯苓2-6份、粉葛根3-10份、生姜1-3份、合欢皮3-6份、黄芩1-5份; 1. A traditional Chinese medicine drinking water preparation for resisting livestock and poultry transportation stress response, characterized in that: it is made of the following raw materials in parts by weight: 1-5 parts of Golden Boiled Grass, 2-8 parts of pinellia chinensis, 2-5 parts of tangerine peel , 2-5 parts of patchouli, 2-6 parts of poria cocos, 3-10 parts of kudzu root, 1-3 parts of ginger, 3-6 parts of Albizia juniper, 1-5 parts of scutellaria baicalensis; 所用辅料:表面活性剂0.05-0.2份、防腐剂0.02-0.2份。 Excipients used: 0.05-0.2 part of surfactant, 0.02-0.2 part of preservative. 2.根据权利要求1所述的抗畜禽运输应激反应的中药饮水剂,其特征在于:由下列重量份的原料制成:金沸草2份、制半夏3份、陈皮3份、广藿香2份、茯苓3份、粉葛根4份、生姜1份、合欢皮3份、黄芩2份; 2. The traditional Chinese medicine drinking water agent for resisting the stress response of livestock and poultry transportation according to claim 1, characterized in that: it is made of the following raw materials in parts by weight: 2 parts of Jinbocao, 3 parts of pinellia, 3 parts of tangerine peel, 2 parts of patchouli, 3 parts of poria cocos, 4 parts of kudzu root, 1 part of ginger, 3 parts of acacia bark, 2 parts of scutellaria baicalensis; 所用辅料:表面活性剂0.08份、防腐剂0.05份。 Excipients used: 0.08 part of surfactant, 0.05 part of preservative. 3.根据权利要求1所述的抗畜禽运输应激反应的中药饮水剂,其特征在于:所述表面活性剂为Tween20、Tween40、Tween80中的一种。 3. The traditional Chinese medicine drinking water agent for resisting livestock and poultry transportation stress according to claim 1, characterized in that: the surfactant is one of Tween20, Tween40, and Tween80. 4.根据权利要求1所述的抗畜禽运输应激反应的中药饮水剂,其特征在于:所述防腐剂为苯甲酸钠、尼泊金乙酯、尼泊金甲酯、山梨酸钾中的一种或几种。 4. the Chinese medicine drinking water agent of anti-livestock and poultry transportation stress response according to claim 1, is characterized in that: described preservative is sodium benzoate, ethylparaben, methylparaben, potassium sorbate one or several. 5.根据权利要求1所述的抗畜禽运输应激反应的中药饮水剂的制备方法,其特征在于:包括以下制备步骤: 5. the preparation method of the Chinese medicine drinking-water preparation of anti-livestock and poultry transportation stress response according to claim 1, is characterized in that: comprise following preparation steps: (1)按上述重量份比例将陈皮、广藿香分别采用水蒸汽蒸馏法提取挥发油,提取的挥发油密闭保存,剩下的水煎部分取出药渣得水相,药渣再加水煎一次,去渣,然后与水蒸汽蒸馏法得到的水相合并,得到水提取液; (1) Extract the volatile oils from tangerine peel and patchouli respectively by steam distillation according to the above weight ratio, and store the extracted volatile oils in airtight storage. The remaining decocted parts are taken out of the dregs to obtain the water phase, and the dregs are decocted once more to remove the volatile oils. The slag is then combined with the water phase obtained by steam distillation to obtain a water extract; (2)将金沸草、制半夏、茯苓、粉葛根、生姜、合欢皮、黄芩混合,加水煎煮2-3次,去渣后与步骤(1)中的陈皮、广藿香水提取液混合得到药液,然后将药液浓缩至药材总重量的2-8倍,得浓缩液; (2) Mix Jinboicao, Zhipinellia, Poria cocos, Pueraria puerariae, ginger, Albizia juniper, and Scutellaria baicalensis, add water and decoct for 2-3 times, remove the slag and mix with the tangerine peel and patchouli perfume extract in step (1) mixing to obtain the medicinal solution, and then concentrating the medicinal solution to 2-8 times the total weight of the medicinal materials to obtain a concentrated solution; (3)将步骤(1)中提取的挥发油与表面活性剂混合,混匀后加入到步骤(2)的浓缩液中,搅拌均匀,最后加入防腐剂,分装、密封。 (3) Mix the volatile oil extracted in step (1) with the surfactant, mix well, add to the concentrated solution in step (2), stir evenly, and finally add preservative, pack and seal.
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